UNITED STATES ENVIRONMENTAL PROTECTION AGENCY 

WASHINGTON, D.C. 20460 

MAR 31 2015 

OFFICE OF CHEMICAL SAFETY 

AND POLLUTION PREVENTION 

MEMORANDUM 

SUBJECT: 

FROM: 

THRU: 

BEAD Chemical Profile (BCP) for Registration Review: Bromuconazole 

(120503) 

Carl Chen, Plant Pathologist 

Biological Analysis Branch 

Rafael Prieto, Environmental Protection Specialist ~ l h, 1 0 ~ . P ,~"D Science Information and Analysis Branch V ""V II"''-" 

Stephen Smearman, Economist 

Economic 

Biological 

Analysis 

and Economic 

Branch 

Analysis 

~~ Division (7503P) 

Arnet Jones, Chief 

Biological Analysis Branch 

Diann 

Science 

Sims, 

Information 

Chief ~ and Analysis Branch 

Economic 

Timothy Kiely, 

Analysis 

Chief 

Branch Q: lA..-\_ ~ 

Biological and Economic Analysi ivision (75 P 

TO: James Parker, Chemical Review Manager 

Risk Management and Implementation Branch 3 

Pesticide Re-evaluatio,n Division (7508P) 

Office of Pesticide Programs (OPP) 

Product Review Panel date: March 25, 2015 

Page 1 
The Biological and Economic Analysis Division (BEAD) Chemical Profile (BCP) provides an 

overview of the pest management role and quantitative usage information available for a 

pesticide. Information provided in this BCP may be used by stakeholders (e.g., users and 

registrants), OPP risk and benefit assessors, OPP risk managers, and the general public during 

the Registration Review process ofbromuconazole. 

Bromuconazole was registered in the United States in 2002. It is a fungicide registered under 

Section 3 of the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) for use on roses in 

greenhouses. It has only one end-use product with an emulsifiable concentrate formulation 

containing 20% of the active ingredient bromuconazole. The fungicide is used as a foliar 

treatment applied in sufficient enough water to cover all above ground plant surfaces (EPA, 

2015). 

Bromuconazole belongs to the triazole chemical group. It is a DMI (DeMethylation Inhibitor) 

fungicide classified by the Fungicide Resistance Action Committee (FRAC) as a FRAC Group 3 

fungicide. DMI fungicides are sterol biosynthesis inhibitors (SBI) but have no cross resistance 

to other SBI classes. In general, Group 3 fungicides have a medium risk of resistance and the 

FRAC SBI Guidelines are available for resistance management (FRAC, 2014). 

Bromuconazole has a federal registration for prevention and control of certain diseases of rose 

such as black spot (Diplocarpon rosaea). However, the California state registration information 

is not found in the National Pesticide Information Retrieval System (NPIRS, 2015). The lack of 

a state registration could limit a pesticide's availability for use to control black spot on roses in 

greenhouses if a state registration is required for its use in a state. 

There have been no BEAD benefits assessments or FIFRA Section 18 emergency exemption 

requests for bromuconazole in the last 10 years. While an emergency exemption request may 

yield information about a chemical's importance or value that is not found in other EPA records, 

the lack of a FIFRA Section 18 assessment by BEAD does not specifically indicate the relative 

importance of this chemical. 

Quantitative usage information for bromuconazole is not available. Obtaining the following 

infonnation may improve future assessments related to the use and importance of 

bromuconazole: 1) total pounds of active ingredient applied per year on a national and/or 

regional basis; 2) percent crop/site treated; 3) application rates: typical and maximum; 4) 

frequency and intervals of application; and 5) efficacy infonnation/product perfonnance. 

REFERENCES 

EPA. 2015. EPA-approved bromuconazole technical and end-use labels. Accessed March 2015 

at http://ofmpub.epa.gov/apex/pesticides/f?p=PPLS: 1. 

FRAC. 2014. Fungicide Resistance Action Committee (FRAC)- 2014 FRAC Code List©. 

Accessed March 2015 at 

http://www.frac.info/frac/publication/anhang/2014 %20 FRA C%20Code%20 List. pdf. 

NPIRS. 2015. Bromuconazole federal/state registrations. National Pesticide Infonnation 

Retrieval System (NRIRS). Accessed March 2015 at http://npirs.ceris.purdue.edu. 

Page 2