| 1.  | I have reviewed this quarterly report on Form 10-Q for the quarter ended March 31, 2011 of Medical Connections Holdings, Inc.; |
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| 2.  | Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact  necessary to make the statements made, in light of the  circumstances  under which such statements were made, not misleading with respect to the period covered by this report; |
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| 3.  | Based  on my  knowledge,  the  financial  statements,  and  other  financial information included in this report, fairly present in all material respects the financial condition,  results of operations and cash flows of the registrant as of, and for, the periods presented in this report; |
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| 4.  | The registrant’s other certifying officer(s) and I are responsible for establishing and maintaining  disclosure controls and procedures (as defined in Exchange  Act Rules  13a-15(e)  and  15d-15(e))  and  internal  control  over financial  reporting (as defined in Exchange Act Rules  13a-15(f) and 15d-15(f)) for the registrant and have: |
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| a)    | Designed  such  disclosure  controls  and  procedures,  or caused  such disclosure  controls and  procedures to be designed  under our  supervision,  to ensure  that  material  information  relating  to  the  registrant, including its  consolidated  subsidiaries,  is made known to us by others within those  entities,  particularly  during the period in which this  report is being prepared; |
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| b)    | Designed such internal control over financial reporting,  or caused such internal control over financial  reporting to be designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial  statements for external purposes in accordance with generally accepted accounting principles; |
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| c)    | Evaluated the  effectiveness of the registrant’s disclosure controls and procedures and presented in this report our  conclusions  about the effectiveness  of the disclosure  controls and procedures,  as of the end of the period covered by this report based on such evaluation; and |
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| d)    | Disclosed  in this  report  any change in the registrant’s internal  control  over  financial  reporting  that  occurred  during  the registrant’s most recent fiscal quarter (the registrant’s fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely to materially  affect, the registrant’s internal control over financial reporting; and |
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| 5.  | The registrant’s other certifying officer(s) and I have disclosed, based  on  our  most  recent  evaluation  of  internal  control  over  financial reporting,  to the registrant’s  auditors and the audit committee of the registrant’s  board of  directors  (or persons  performing  the equivalent functions): |
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| a)    | All significant  deficiencies  and material  weaknesses in the design or operation of internal  control over  financial  reporting  which are  reasonably likely to  adversely  affect  the registrant’s  ability  to record, process, summarize and report financial information; and |
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| b)    | Any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant’s internal control over financial reporting. |
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| Date:  May 13, 2011 |                                 |
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|                          |                                 |
| By:                           | /s/ Jeffrey Rosenfeld      |   |
|                          | Jeffrey Rosenfeld,                   |   |
|                          | Chief Executive Officer and Director |   |