UNITED STATES
SECURITIES AND EXCHANGE COMMISSIONWashington, D.C. 20549

---

FORM 10-QSB

---

|ý                                                             | QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 
|------------------------------------------------------------- | ----------------------------------------------------------------------------------------
|FOR THE PERIOD ENDED SEPTEMBER 30, 2007                      
|OR                                                           
|o                                                             | TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934
|FOR THE TRANSITION PERIOD
FROM                             TO

COMMISSION FILE NUMBER 0-50295

---

ADVANCED CELL TECHNOLOGY, INC.(EXACT NAME OF SMALL BUSINESS ISSUER AS SPECIFIED IN ITS CHARTER)

|DELAWARE(STATE OR OTHER JURISDICTION OF
INCORPORATION OR ORGANIZATION)                                          |  | 87-0656515(I.R.S. EMPLOYER IDENTIFICATION NO.)
|--------------------------------------------------------------------------------------------------------------- |  | ----------------------------------------------
|1201 HARBOR BAY PARKWAY, ALAMEDA, CALIFORNIA 94502(ADDRESS, INCLUDING ZIP CODE, OF PRINCIPAL EXECUTIVE OFFICES)
|REGISTRANT'S TELEPHONE NUMBER, INCLUDING AREA CODE:(510) 748-4900                                              

SECURITIES
REGISTERED PURSUANT TO SECTION 12(b) OF THE ACT:None

SECURITIES
REGISTERED PURSUANT TO SECTION 12(g) OF THE ACT: Common Stock, $0.001 par value per share

Indicate by check mark whether the small business issuer (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities
Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the small business issuer was required to file such reports), and (2) has been subject to such filing
requirements for the past 90 days.

Yes ý    No o

Indicate the number of shares outstanding of each of the issuer's classes of common stock, as of the latest practicable date.

|Class:                                   |  | Outstanding at November 1, 2007:
|---------------------------------------- |  | --------------------------------
|Common Stock, $0.001 par value per share |  | 81,333,064 shares               

Transitional
Small Business Disclosure format (check one)

Yes o    No ý



---





ADVANCED CELL TECHNOLOGY, INC.    INDEX

|PART I. FINANCIAL INFORMATION |                                                                     | 
|----------------------------- | ------------------------------------------------------------------- | 
|                              | ITEM 1. FINANCIAL STATEMENTS                                        | 
|                              | ITEM 2. MANAGEMENT'S DISCUSSION AND ANALYSIS OR PLAN OF OPERATION   | 
|                              | ITEM 3. CONTROLS AND PROCEDURES                                     | 
|PART II. OTHER INFORMATION    |                                                                     | 
|                              | ITEM 1. LEGAL PROCEEDINGS                                           | 
|                              | ITEM 2. UNREGISTERED SALES OF EQUITY SECURITIES AND USE OF PROCEEDS | 
|                              | ITEM 3. DEFAULTS UPON SENIOR SECURITIES                             | 
|                              | ITEM 4. SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS         | 
|                              | ITEM 5. OTHER INFORMATION                                           | 
|                              | ITEM 6. EXHIBITS                                                    | 
|SIGNATURE                     |                                                                     | 

CAUTIONARY NOTE REGARDING FORWARD-LOOKING STATEMENTS

This Quarterly Report on Form 10-QSB and the materials incorporated herein by reference contain forward-looking statements that involve risks
and uncertainties. We use words such as "may," "assumes," "forecasts," "positions," "predicts," "strategy," "will," "expects," "estimates," "anticipates," "believes," "projects," "intends," "plans,"
"budgets," "potential," "continue" and variations thereof, and other statements contained in quarterly report, and the exhibits hereto, regarding matters that are not historical facts and are
forward-looking statements. Because these
statements involve risks and uncertainties, as well as certain assumptions, actual results may differ materially from those expressed or implied by such forward-looking statements. Factors that could
cause actual results to differ materially include, but are not limited to risks inherent in: our early stage of development, including a lack of operating history, lack of profitable operations and
the need for additional capital; the development and commercialization of largely novel and unproven technologies and products; our ability to protect, maintain and defend our intellectual property
rights; uncertainties regarding our ability to obtain the capital resources needed to continue research and development operations and to conduct research, preclinical development and clinical trials
necessary for regulatory approvals; uncertainty regarding the outcome of clinical trials and our overall ability to compete effectively in a highly complex, rapidly developing, capital intensive and
competitive industry. See "RISK FACTORS THAT MAY AFFECT OUR BUSINESS" set forth on page 31 herein for a more complete discussion of these factors. Readers are cautioned not to place undue
reliance on these forward-looking statements, which speak only as of the date that they are made. We undertake no obligation to publicly update or revise any forward-looking statements, whether as a
result of new information, future events or otherwise.

Forward-looking
statements include our plans and objectives for future operations, including plans and objectives relating to our products and our future economic performance.
Assumptions relating to the foregoing involve judgments with respect to, among other things, future economic, competitive and market conditions, future business decisions, and the time and money
required to successfully complete development and commercialization of our technologies, all of which are difficult or impossible to predict accurately and many of which are beyond our control.
Although we believe that the assumptions underlying the forward-looking statements contained herein are reasonable, any of those assumptions could prove inaccurate and, therefore, we cannot assure you
that the results contemplated in any of the forward-looking statements contained herein will be realized. Based on the significant uncertainties inherent in the forward-looking statements included
herein, the inclusion of any such statement should not be regarded as a representation by us or any other person that our objectives or plans will be achieved.

2

---





PART I.    FINANCIAL INFORMATION

ADVANCED CELL TECHNOLOGY, INC. AND SUBSIDIARY        BALANCE SHEET

|                                                                          |                                                                                                                              | September 30,
2007 |             | December 31,
2006 |  
|------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------------------- | ------------------ | ----------- | ----------------- | -
|
|ASSETS                                                                    |                                                                                                                              |                    |             |                   |  
|Current assets:                                                           |                                                                                                                              |                    |             |                   |  
|                                                                          | Cash and cash equivalents                                                                                                    |                    | $           | 6,682,572         |  
|                                                                          | Accounts receivable, net of allowance for doubtful accounts of $0 and $236,399                                               |                    |             | 28,397            |  
|                                                                          | Prepaid expenses                                                                                                             |                    |             | 98,182            |  
|                                                                          | Deferred royalty fees, current portion                                                                                       |                    |             | 313,775           |  
|                                                                          |                                                                                                                              |                    |             |                   |  
|Total current assets                                                      |                                                                                                                              |                    | 7,122,925   |                   |  
|Property and equipment, net                                               |                                                                                                                              |                    | 1,237,759   |                   |  
|Deferred royalty fees, less current portion                               |                                                                                                                              |                    | 1,315,248   |                   |  
|Deposits                                                                  |                                                                                                                              |                    | 128,841     |                   |  
|Deferred issuance costs, net of amortization of $4,077,372 and $1,035,120 |                                                                                                                              |                    | 5,826,401   |                   |  
|                                                                          |                                                                                                                              |                    |             |                   |  
|Total assets                                                              |                                                                                                                              | $                  | 15,631,174  |                   | $
|                                                                          |                                                                                                                              |                    |             |                   |  
|LIABILITIES AND STOCKHOLDERS' DEFICIT                                     |                                                                                                                              |                    |             |                   |  
|Current liabilities:                                                      |                                                                                                                              |                    |             |                   |  
|                                                                          | Accounts payable                                                                                                             |                    | $           | 5,974,992         |  
|                                                                          | Accrued expenses                                                                                                             |                    |             | 1,151,524         |  
|                                                                          | Deferred revenue, current portion                                                                                            |                    |             | 497,374           |  
|                                                                          | Interest payable                                                                                                             |                    |             | 0                 |  
|                                                                          | Advances payableother                                                                                                       |                    |             | 130,000           |  
|                                                                          | 2005 Convertible debenture and embedded derivatives, net of discounts of $1,101,322 and $3,713,554                           |                    |             | 1,976,205         |  
|                                                                          | 2006 Convertible debenture and embedded derivatives (fair value $2,248,924 and $5,472,177)                                   |                    |             | 1,804,993         |  
|                                                                          | 2007 Convertible debenture and embedded derivative (fair value of $2,749,951)                                                |                    |             | 481,161           |  
|                                                                          | Warrant and Option Derivativescurrent portion                                                                               |                    |             | 595,169           |  
|                                                                          | Capital leasescurrent portion                                                                                               |                    |             | 51,095            |  
|                                                                          | Notes payableother                                                                                                          |                    |             | 468,425           |  
|                                                                          |                                                                                                                              |                    |             |                   |  
|                                                                          | Total current liabilities                                                                                                    |                    |             | 13,130,936        |  
|                                                                          | 2005 Convertible debenture and embedded derivatives, less current portion and net of discounts of $0 and $1,571,332          |                    |             | 0                 |  
|                                                                          | 2006 Convertible debenture and embedded derivatives, less current portion (fair value $7,389,322unaudited, and $12,768,413) |                    |             | 5,930,692         |  
|                                                                          | 2007 Convertible debenture and embedded derivative less current portion (fair value of $9,035,553)                           |                    |             | 1,580,958         |  
|                                                                          | Warrant and Option Derivatives, less current portion                                                                         |                    |             | 19,854,865        |  
|                                                                          | Capital leases, less current portion                                                                                         |                    |             | 0                 |  
|                                                                          | Deferred revenue, less current portion                                                                                       |                    |             | 1,658,829         |  
|                                                                          |                                                                                                                              |                    |             |                   |  
|Total liabilities                                                         |                                                                                                                              |                    | 42,156,280  |                   |  
|                                                                          |                                                                                                                              |                    |             |                   |  
|Commitments and contingencies                                             |                                                                                                                              |                    |            |                   |  
|Stockholders' deficit:                                                    |                                                                                                                              |                    |             |                   |  
|                                                                          | Preferred stock, $0.001 par value; 50,000,000 shares authorized, 0 issued and outstanding                                    |                    |             |                  |  
|                                                                          | Common stock, $0.001 par value; 500,000,000 shares authorized, 75,465,805 issued and outstanding                             |                    |             | 75,466            |  
|                                                                          | Additional paid-in capital                                                                                                   |                    |             | 32,185,904        |  
|                                                                          | Accumulated deficit                                                                                                          |                    |             | (58,786,476       | )
|                                                                          |                                                                                                                              |                    |             |                   |  
|Total stockholders' deficit                                               |                                                                                                                              |                    | (26,525,106 | )                 |  
|                                                                          |                                                                                                                              |                    |             |                   |  
|Total liabilities and stockholders' deficit                               |                                                                                                                              | $                  | 15,631,174  |                   | $
|                                                                          |                                                                                                                              |                    |             |                   |  

The accompanying notes are an integral part of these financial statements

3

---





ADVANCED CELL TECHNOLOGY, INC. AND SUBSIDIARY        STATEMENTS OF OPERATIONS        (UNAUDITED)

|                                                                  |                                                                        | Three months ended September 30, |            | Nine months ended September 30, |  
|----------------------------------------------------------------- | ---------------------------------------------------------------------- | -------------------------------- | ---------- | ------------------------------- | -
|
|Revenue:                                                          |                                                                        |                                  |            |                                 |  
|                                                                  | License fees and royalties                                             |                                  | $          | 124,337                         |  
|                                                                  | Cost of revenue                                                        |                                  |            | 85,319                          |  
|                                                                  |                                                                        |                                  |            |                                 |  
|                                                                  | Gross profit                                                           |                                  |            | 39,018                          |  
|                                                                  |                                                                        |                                  |            |                                 |  
|Operating expenses:                                               |                                                                        |                                  |            |                                 |  
|                                                                  | Research and development                                               |                                  |            | 2,987,420                       |  
|                                                                  | In process research and development                                    |                                  |            | 3,758,838                       |  
|                                                                  | Grant reimbursements                                                   |                                  |            |                                |  
|                                                                  | General and administrative                                             |                                  |            | 1,617,683                       |  
|                                                                  |                                                                        |                                  |            |                                 |  
|Total operating expenses                                          |                                                                        |                                  | 8,363,941  |                                 |  
|                                                                  |                                                                        |                                  |            |                                 |  
|Loss from operations                                              |                                                                        |                                  | (8,324,923 | )                               |  
|                                                                  |                                                                        |                                  |            |                                 |  
|Other income (expense):                                           |                                                                        |                                  |            |                                 |  
|                                                                  | Interest income                                                        |                                  |            | 20,042                          |  
|                                                                  | Gain on sale of asset                                                  |                                  |            |                                |  
|                                                                  | Loss on extinguishment of debt                                         |                                  |            |                                |  
|                                                                  | Gain on settlement of debt                                             |                                  |            |                                |  
|                                                                  | Interest expense and late fees                                         |                                  |            | (2,106,741                      | )
|                                                                  | Charges related to issuance of Convertible Debentures & Warrants       |                                  |            |                                |  
|                                                                  | Charges related to repricing of 2005 Convertible Debentures & Warrants |                                  |            |                                |  
|                                                                  | Adjustments to fair value of derivatives                               |                                  |            | 6,132,251                       |  
|                                                                  | Charges related to issuance of 2007 Convertible Debentures & Warrants  |                                  |            | (3,871,656                      | )
|                                                                  |                                                                        |                                  |            |                                 |  
|Total other income (expense)                                      |                                                                        |                                  | 173,896    |                                 |  
|                                                                  |                                                                        |                                  |            |                                 |  
|Net income/(Loss)                                                 |                                                                        | $                                | (8,151,027 | )                               | $
|                                                                  |                                                                        |                                  |            |                                 |  
|Basic earnings per share                                          |                                                                        | $                                | (0.17      | )                               | $
|                                                                  |                                                                        |                                  |            |                                 |  
|Weighted average shares used in computation of earnings per share |                                                                        |                                  |            |                                 |  
|                                                                  | Basic                                                                  |                                  |            | 47,109,090                      |  

The
accompanying notes are an integral part of these financial statements

4

---



ADVANCED CELL TECHNOLOGY, INC. AND SUBSIDIARY        STATEMENTS OF CASH FLOWS        (UNAUDITED)

|                                                                            |                                                       | For the Nine Months Ended September 30, |            
|--------------------------------------------------------------------------- | ----------------------------------------------------- | --------------------------------------- | -----------
|
|CASH FLOWS FROM OPERATING ACTIVITIES:                                       |                                                       |                                         |            
|Net loss                                                                    |                                                       | $                                       | (16,912,961
|Adjustments to reconcile net loss to net cash used in operating activities: |                                                       |                                         |            
|                                                                            | Depreciation and amortization                         |                                         |            
|                                                                            | Amortization of deferred charges                      |                                         |            
|                                                                            | Amortization of deferred revenue                      |                                         |            
|                                                                            | Stock based compensation                              |                                         |            
|                                                                            | Amortization of deferred issuance costs               |                                         |            
|                                                                            | Shares issued for services                            |                                         |            
|                                                                            | Warrants issued for services                          |                                         |            
|                                                                            | Amortization of deferred compensation                 |                                         |            
|                                                                            | Charges related to issuance of 2007 debentures        |                                         |            
|                                                                            | Amortization of discounts                             |                                         |            
|                                                                            | Gain on extinguishment of debt                        |                                         |            
|                                                                            | Adjustments to Fair Value of Derivatives              |                                         |            
|                                                                            | Repricing of 2005 Convertible Debentures and Warrants |                                         |            
|                                                                            | Issuance of Convertible Debentures                    |                                         |            
|                                                                            | Shares issued for legal services                      |                                         |            
|                                                                            | Shares issued for license fees                        |                                         |            
|                                                                            | Shares issued for board fees                          |                                         |            
|                                                                            | Warrants issued to consultants                        |                                         |            
|                                                                            | Shares issued to employees                            |                                         |            
|                                                                            | Changes in operating assets and liabilities:          |                                         |            
|(Increase) decrease in:                                                     |                                                       |                                         |            
|                                                                            | Accounts receivable                                   |                                         |            
|                                                                            | Prepaid expenses                                      |                                         |            
|                                                                            | Deferred charges                                      |                                         |            
|                                                                            | Deposits                                              |                                         |            
|Increase (decrease) in:                                                     |                                                       |                                         |            
|                                                                            | Accounts payable and accrued expenses                 |                                         |            
|                                                                            | Interest payable                                      |                                         |            
|                                                                            | Deferred revenue                                      |                                         |            
|                                                                            |                                                       |                                         |            
|Net cash used in operating activities                                       |                                                       |                                         | (14,205,837
|                                                                            |                                                       |                                         |            
|CASH FLOWS FROM INVESTING ACTIVITIES:                                       |                                                       |                                         |            
|Purchases of property and equipment                                         |                                                       |                                         | (45,123    
|Payment of deposits                                                         |                                                       |                                         | 5,000      
|Charges related to Mytogen acquisition                                      |                                                       |                                         | 3,758,838  
|                                                                            |                                                       |                                         |            
|Net cash used in investing activities                                       |                                                       |                                         | 3,718,735  
|                                                                            |                                                       |                                         |            
|CASH FLOWS FROM FINANCING ACTIVITIES:                                       |                                                       |                                         |            
|Proceeds from notes                                                         |                                                       |                                         |           
|Proceeds from exercise of warrants                                          |                                                       |                                         |           
|Payments on Convertible Debentures                                          |                                                       |                                         | (139,123   
|Proceeds from 2007 Convertible Debentures, net of costs of $1,151,800       |                                                       |                                         | 8,848,200  
|Payments on notes and leases                                                |                                                       |                                         | (58,470    
|Settlement payment                                                          |                                                       |                                         | (170,249   
|                                                                            |                                                       |                                         |            
|Net cash paid by financing activities                                       |                                                       |                                         | 8,480,358  
|                                                                            |                                                       |                                         |            
|Net increase / (decrease) in cash                                           |                                                       |                                         | (2,006,764 
|Cash and cash equivalents, beginning of period                              |                                                       |                                         | 8,689,336  
|                                                                            |                                                       |                                         |            
|Cash and cash equivalents, end of period                                    |                                                       |                                         | 6,682,572  
|                                                                            |                                                       |                                         |            
|Cash paid for:                                                              |                                                       |                                         |            
|                                                                            | Interest                                              |                                         | $          
|                                                                            | Income taxes                                          |                                         | $          

The accompanying notes are an integral part of these financial statements

5

---



Supplemental schedule of non-cash financing activities:

During the nine months ended September 30, 2007:

The Company issued approximately 10,189,994 shares of common stock in redemption of convertible debentures with a face value of approximately $5,073,000

The
Company issued approximately 16,457,315 shares of common stock in conversion of convertible debentures with a face value of approximately $8,343,000

The
Company issued approximately 36,000 shares of common stock in payment of board fees of approximately $21,000.

The
Company issued approximately 800,000 shares of common stock in payment of license fees of $608,000.

The
Company issued approximately 515,000 shares of common stock in payment of employee bonuses of $407,000.

The
Company issued approximately 85,000 shares of common stock in settlement of legal fees of approximately $68,000.

The
Company issued approximately 8,000,000 shares of common stock in acquisition of Mytogen.

6

---





ADVANCED CELL TECHNOLOGY, INC. AND SUBSIDIARY        STATEMENT OF STOCKHOLDERS' DEFICIT        FOR THE NINE MONTH PERIOD ENDED SEPTEMBER 30, 2007 (UNAUDITED)

|                                                      |  | Common Stock |  |   |        |  |   |            | 
|----------------------------------------------------- |  | ------------ |  | - | ------ |  | - | ---------- | 
|
|
|Balance at December 31, 2006                          |  | 39,318,070   |  | $ | 39,318 |  | $ | 12,291,873 | 
|Convertible Debenture Redemption                      |  | 10,189,994   |  |   | 10,190 |  |   | 4,923,575  | 
|Convertible Debenture Conversion                      |  | 16,457,315   |  |   | 16,457 |  |   | 11,009,009 | 
|Issuance of stock in payment of board fees            |  | 35,909       |  |   | 36     |  |   | 20,716     | 
|Stock based compensation                              |  |             |  |   |       |  |   | 447,990    | 
|Issuance of stock in payment of license fees          |  | 800,000      |  |   | 800    |  |   | 607,200    | 
|Issuance of stock in payment of employee bonuses      |  | 515,000      |  |   | 515    |  |   | 406,335    | 
|Issuance of stock in payment of legal fees            |  | 85,000       |  |   | 85     |  |   | 67,915     | 
|Issuance of stock in acquisition of Mytogen           |  | 8,064,517    |  |   | 8,064  |  |   | 2,411,291  | 
|Net loss for the nine months ended September 30, 2007 |  |             |  |   |       |  |   | 0          | 
|                                                      |  |              |  |   |        |  |   |            | 
|Balance at September 30, 2007                         |  | 75,465,805   |  | $ | 75,466 |  | $ | 32,185,904 | 
|                                                      |  |              |  |   |        |  |   |            | 

The
accompanying notes are an integral part of these financial statements

7

---





ADVANCED CELL TECHNOLOGY, INC. AND SUBSIDIARY        NOTES TO FINANCIAL STATEMENTS        September 30, 2007        (unaudited)

1. ORGANIZATIONAL MATTERS

Organization

On January 31, 2005, Advanced Cell Technology, Inc. (formerly known as A.C.T. Holdings, Inc.) (the "Company") completed a merger with
Advanced Cell, Inc. (formerly known as Advanced Cell Technology, Inc.), a Delaware corporation ("ACT"), pursuant to which a wholly-owned subsidiary of the Company merged with and into
ACT, with ACT remaining as the surviving corporation and a wholly-owned subsidiary of the Company. Upon the completion of the merger, the Company ceased all of its pre-merger operations
and adopted the business of ACT.

Prior
to the merger, the Company had minimal business, operations, revenues and assets, and had been involved in an industry entirely unrelated to the business of ACT. Therefore, the
acquisition of ACT by the Company represented a complete change in the nature of the Company's business and operations, and changed the nature of any prior investment in the Company.

The
transaction has been accounted for as a recapitalization of ACT, the accounting acquirer. The historical financial statements presented for periods prior to the merger are those of
ACT.

On
November 18, 2005, a majority of the Company's stockholders approved the reincorporation of the Company from the state of Nevada to the state of Delaware pursuant to a merger
of the Company with and into a newly formed Delaware corporation, followed by a "roll up" merger to combine the operating subsidiary with the Company.

Nature of Business

The Company is a biotechnology company focused on developing and commercializing human embryonic and adult stem cell technology in the emerging field of
regenerative medicine. Principal activities to date have included obtaining financing, securing operating facilities and conducting research and development. The Company has no therapeutic products
currently available for sale and does not expect to have any therapeutic products commercially available for sale for a period of years, if at all. These factors indicate that the Company's ability to
continue its research and development activities is dependent upon the ability of management to obtain additional financing as required.

Going Concern

As reflected in the accompanying financial statements, the Company has losses from operations, negative cash flows from operations, a substantial stockholders'
deficit and current liabilities exceed current assets. The Company will thus not be able to continue as a going concern and fund cash requirements for operations through June 30, 2008 with
current cash reserves. As more fully described in Note 3Convertible Debentures2007, the Company was able to raise cash in the quarter ended September 30, 2007.
Notwithstanding success in raising capital, there continues to be substantial doubt about the Company's ability to continue as a going concern.

In
view of the matters described in the preceding paragraph, recoverability of a major portion of the recorded asset amounts shown in the accompanying consolidated balance sheet is
dependent upon continued operations of the Company, which, in turn, is dependent upon the Company's ability to

8

---



continue
to raise capital and ultimately generate positive cash flows from operations. The financial statements do not include any adjustments relating to the recoverability and classification of
recorded asset amounts or amounts and classifications of liabilities that might be necessary should the Company be unable to continue its existence.

Over
the next nine months, management intends to take the following steps that it believes will be sufficient to provide the Company with the ability to continue in existence:



2. SIGNIFICANT ACCOUNTING POLICIES

Basis of PresentationThe accompanying interim condensed consolidated financial statements are
unaudited and have been prepared in accordance with accounting principles generally accepted in the United States of America ("GAAP") including those for interim financial information and with the
instructions for Form 10-QSB and Article 10 of Regulation S-X issued by the Securities and Exchange Commission ("SEC"). Accordingly, they do not include all of the
information and note disclosures required by GAAP for complete financial statements. In the opinion of management, all adjustments (consisting of normal recurring adjustments) considered necessary for
a fair presentation have been reflected in these interim financial statements. These financial statements should be read in conjunction with the audited financial statements and notes for the year
ended December 31, 2006 included in the Company's Annual Report on Form 10-KSB filed with the SEC on March 19, 2007.

Use of EstimatesThese condensed consolidated financial statements have been prepared in accordance
with accounting principles generally accepted in the United States and, accordingly, require management to make estimates and assumptions that affect the reported amounts of assets and liabilities at
the date of the financial statements and the reported amounts of revenues and expenses during the reporting period. Specifically, our management has estimated variables used to calculate the Black
Scholes and binomial lattice model calculations used to value derivative instruments discussed below under "Valuation of Derivative Instruments". In addition, management has estimated the expected
economic life and value of our licensed technology, our net operating loss for tax purposes, share-based payments to compensation to employees, directors, consultants and investment banks, the

9

---



useful
lives of our fixed assets and our allowance for bad debts. Actual results could differ from those estimates.

ReclassificationsCertain prior year financial statement balances have been reclassified to conform to
the current year presentation. These reclassifications have no effect on the recorded net loss.

Valuation of Derivative InstrumentsFAS 133, "Accounting for Derivative Instruments and Hedging
Activities" requires bifurcation of embedded derivative instruments and measurement of fair value for accounting purposes. In addition, FAS 155, "Accounting for Certain Hybrid Financial
Instruments" requires measurement of fair values of hybrid financial instruments for accounting purposes. We applied the accounting proscribed in FAS 155 to account for the 2006 Convertible
Debentures described below in Note 4Convertible Debentures 2006. In determining the appropriate fair value, the Company uses a variety of valuation techniques including Black
Scholes models, Binomial Option Pricing models, Standard Put Option Binomial models and net present value of certain penalty amounts. Derivative liabilities are adjusted to reflect fair value at each
period end, with any increase or decrease in the fair value being recorded in results of operations as Adjustments to Fair Value of Derivatives. The effects of interactions between embedded
derivatives are calculated and accounted for in arriving at the overall fair value of the financial instruments. In addition, the fair values of freestanding derivative instruments such as warrant
derivatives are valued using Black Scholes models.

Revenue RecognitionOur revenues are generated from license and research agreements with
collaborators. Licensing revenue is recognized on a straight-line basis over the shorter of the life of the license or the estimated economic life of the patents related to the license.
Deferred revenue represents the portion of the license and other payments received that has not been earned. Costs associated with the license revenue are deferred and recognized over same term as the
revenue. Reimbursements of research expense pursuant to grants are recorded in the period during which collection of the reimbursement becomes assured, because the reimbursements are subject to
approval.

Net Loss Per ShareWe use FAS No. 128, "Earnings Per Share" for calculating the basic and
diluted loss per share. We compute basic loss per share by dividing net loss and net loss attributable to common shareholders by the weighted average number of common shares outstanding. Diluted loss
per share is computed similar to basic loss per share except that the denominator is increased to include the number of additional common shares that would have been outstanding if the potential
shares had been issued and if the additional shares were dilutive. Common equivalent shares are excluded from the computation of net loss per share if their effect is anti-dilutive.

For
the three months ended September 30, 2007, approximately 58,000,000 potentially dilutive shares were excluded from the shares used to calculate diluted earnings per share as
their inclusion would be anti-dilutive. There were 23,000,000 potentially dilutive shares at September 30, 2006.

Income TaxesDeferred income taxes are provided using the liability method whereby deferred tax assets
are recognized for deductible temporary differences and operating loss and tax credit carryforwards and deferred tax liabilities are recognized for taxable temporary differences. Temporary differences
are the differences between the reported amounts of assets and liabilities and their tax bases. Deferred tax assets are reduced by a valuation allowance when, in the opinion of management, it

10

---



is
more likely than not that some portion or all of the deferred tax assets will not be realized. Deferred tax assets and liabilities are adjusted for the effects of the changes in tax laws and rates
of the date of enactment.

When
tax returns are filed, it is highly certain that some positions taken would be sustained upon examination by the taxing authorities, while others are subject to uncertainty about
the merits of the position taken or the amount of the position that would be ultimately sustained. The benefit of a tax position is recognized in the financial statements in the period during which,
based on all available evidence, management believes it is more likely than not that the position will be sustained upon examination, including the resolution of appeals or litigation processes, if
any. Tax positions taken are not offset or aggregated with other positions. Tax positions that meet the more-likely-than-not recognition threshold are measured
as the largest amount of tax benefit that is more than 50 percent likely of being realized upon settlement with the applicable taxing authority. The portion of the benefits associated with tax
positions taken that exceeds the amount measured as described above is reflected as a liability for unrecognized tax benefits in the accompanying balance sheet along with any associated interest and
penalties that would be payable to the taxing authorities upon examination.

Interest
and penalties associated with unrecognized tax benefits are classified as additional income taxes in the statement of income.

Recent Accounting Pronouncements

Effective January 1, 2007, the Company adopted FSP No. FIN 48-1, "Definition of Settlement in FASB Interpretation No. 48," (FSP FIN
48-1), which was issued on May 2, 2007. FSP FIN 48-1 amends FIN 48 to provide guidance on how an entity should determine whether a tax position is effectively settled
for the purpose of recognizing previously unrecognized tax benefits. The term "effectively settled" replaces the term "ultimately settled" when used to describe recognition, and the terms "settlement"
or "settled" replace the terms "ultimate settlement" or "ultimately settled" when used to describe measurement of a tax position under FIN 48. FSP FIN 48-1 clarifies that a tax position
can be effectively settled upon the completion of an examination by a taxing authority without being legally extinguished. For tax positions considered effectively settled, an entity would recognize
the full amount of tax benefit, even if the tax position is not considered more likely than not to be sustained based solely on the basis of its technical merits and the statute of limitations remains
open. The adoption of FSP FIN 48-1 did not have an impact on the accompanying financial statements.

3. CONVERTIBLE DEBENTURES2007

On August 31, 2007 we entered into a Securities Purchase Agreement with accredited investors for the issuance of an aggregate of $12,550,000 principal
amount of convertible debentures with an original issue discount of $2,550,000 representing approximately 20.3%. In connection with the closing of the sale of the debentures, we received gross
proceeds of $10,000,000. The convertible debentures are convertible at the option of the holders into 36,911,765 shares of Common Stock at a fixed conversion price of $0.34 per share, subject to
anti-dilution and other customary adjustments. In connection with the Securities Purchase Agreement, we also issued warrants to purchase an aggregate of 43,240,655

11

---



shares
of our Common Stock. The term of the warrants is five years and the exercise price is $0.38 per share, subject to anti-dilution and other customary adjustments. The investors have
contractually agreed to restrict their ability to convert the convertible debentures, exercise the warrants and exercise the additional investment right and receive shares of our Common Stock such
that the number of shares of our Common Stock held by them and their affiliates after such conversion or exercise does not exceed 4.99% of our then issued and outstanding shares of our Common Stock.

The
agreements entered into provide that the Company will pay certain cash amounts as liquidated damages in the event that the Company does not maintain an effective registration
statement, or if the Company fails to timely execute stock trading activity.

Under
the terms of the agreements, principal amounts owed under the debentures become due and payable commencing six months following closing of the transaction. At that time. And each
month thereafter, the Company is required to either repay 1/30 of the outstanding balance owed in common stock at the lesser of $0.34 per share or 80% of the prior ten day's average closing stock
price, immediately preceeding the redemption. The agreements also provide that the Company may force conversion of outstanding amounts owed under the debentures into comoon stock, if the Company has
met certain conditions and milestones, and additionally, has a stock price for 20 consecutive trading days that exceeds 200% of the conversion price.

The
agreement included a number of other embedded derivative instruments, and the Company has complied with the provisions of FAS 155 "Accounting for Certain Hybrid Financial
Instruments", and recorded the fair value of the convertible debentures, and related embedded derivatives, as of August 31, 2007. The fair value of the debentures and related derivative
instruments was valued using a combination of Binomial and Black Scholes models, resulting in a fair value of $11,875,539. The excess of this value over the face value of the Convertible Debentures
was recorded through the results of operations as a debit to Discount on 2007 Convertible Debentures.

The
2007 Convertible debentures and related embedded derivatives outstanding at September 30, 2007 were again valued at fair value using a combination of Binomial and Black
Scholes models, resulting in a decrease in the fair value of the liability of approximately $2,120,000 which was recorded through the results of operations as a credit to Adjustments to Fair Value of
Derivatives.

In
connection with this financing, we paid cash fees to a broker-dealer of $1,001,800 and issued a warrant to purchase 6,328,890 shares of Common Stock at an exercise price of $0.38 per
share. The initial fair value of the warrant was estimated at approximately $2,025,000 using the Black Scholes pricing model. The assumptions used in the Black Scholes model are as follows:
(1) dividend yield of 0%; (2) expected volatility of 151%, (3) risk-free interest rate of 4.25%, and (4) expected life of 5 years. Cash fees paid, and
the initial fair value of the warrant, have been capitalized as debt issuance costs and are being amortized over 36 months, and as redemptions occur the Company writes off the proportional
amount of the original deferred issuance cost to interest expense. During the three months ended September 30, 2007 a decrease in the fair value of the embedded derivative amounts of
approximately $9,000 was recorded through results of operations as a credit to Adjustment to Fair Value of Derivatives.

12

---



For
financial reporting purposes, this acquisition is being recorded in accordance with FAS 155, and is subject to two discounts: the discount related to the issuance of warrants in
conjunction with the financing and the Original Issue Discount (OID), being the difference between the face value of the debentures issued and the $10,000,000 gross cash receipts from the issue. Due
to the large number of warrants issued, and the nature and size of the OID, the total value of the two discounts exceeded the value of the cash received by $4,425,539. This resulted in the unusual
situation where the debenture was reflected in the balance sheet as an asset. Notwithstanding that this treatment was in accordance with GAAP accounting, the Company felt that it did not give the
reader of the financial statements the clarity of understanding that would be desired.

As
result, the Company decided that the transaction is better reflected in the financial statements if the total value of Discounts related to the transaction which are carried forward
in the Balance Sheet and amortized over time are equal to or less than the total amount of cash received in the transaction. It was determined that the amount of the Discounts should be reduced to
$10,000,000. The Company has written off the excess of the total discounts over the dollar value of gross cash receipts through the statement of operations with a debit totaling $4,425,539 to "Charges
Related to the Issuance of 2007 Convertible Debenture & Warrants."

The
following table summarizes the 2007 Convertible Debentures and discounts outstanding at September 30, 2007 (unaudited):

2007 Convertible debentures at fair value

$
11,785,504Warrant derivative discount


(7,295,798
)Original issue discount


(2,427,587
)Net convertible debentures


2,062,119Less current portion


(481,161
)2007 Convertible debentures and embedded derivatives-long term

$
1,580,958


As
of September 30, 2007, the outstanding principle amount for the 2007 Convertible Debentures is $12,550,000.

4. CONVERTIBLE DEBENTURES2006

On September 6, 2006, we entered into a Securities Purchase Agreement with accredited investors for the issuance of an aggregate of $10,981,250 principal
amount of convertible debentures with an original issue discount of $2,231,250 representing approximately 20.3%. In connection with the closing of the sale of the debentures, we received gross
proceeds of $8,750,000. The 2006 convertible debentures and related embedded derivatives outstanding at September 30, 2007 were again valued at fair value using a combination of Binomial and
Black Scholes models, resulting in a decrease in the fair value of the liability of approximately $2,348,000 which was recorded through the results of operations as a credit to Adjustments to Fair
Value of Derivatives.

13

---



The
following table summarizes the 2006 Convertible Debentures and discounts outstanding at September 30, 2007 (unaudited):

2006 Convertible debentures at fair value

$
9,638,246Warrant derivative discount


(1,299,620
)Original issue discount


(602,941
)Net convertible debentures


7,735,685Less current portion


(1,804,993
)2006 Convertible debentures and embedded derivatives-long term

$
5,930,692


As
of September 30, 2007, the outstanding principle amount for the 2006 Convertible Debentures is $7,419,574.

5. CONVERTIBLE DEBENTURES2005

On September 15, 2005, we entered into a Securities Purchase Agreement with accredited investors for the issuance of an aggregate of $22,276,250 principal
amount of convertible debentures with an original issue discount of $4,526,250 representing approximately 20.3%. In connection with the closing of the sale of the debentures, we received gross
proceeds of $17,750,000.

The
agreement included a number of embedded derivative instruments that required separate valuation in accordance with the requirements of FAS 133, EITF 05-04 and
related accounting literature. The following summarizes the fair values of embedded derivatives at December 31, 2006 and September 30, 2007, followed by a description of the valuation
methodology utilized to determine fair values:

Embedded Derivative Liability (Asset)

Fair value
December 31, 2006

Fair value
September 30, 2007
(unaudited)Conversion Feature

$
1,104,414

$
279,107Anti-dilution protection


2,107,767


130,209Default provisions


46,692


5,042Right to provide future financing


0


0Company right to force conversion


(185,091
)

(6,484
)$
3,070,782

$
407,874


The
fair value of the derivative for the conversion feature was valued as an American call option using the Binomial Option Pricing Model with the following inputs: (1) closing
stock price of $0.30 at September 30, 2007 (2) exercise price equal to the $0.34 conversion price (3) volatility between 106.64% to 201.55% based upon the Company's stock trading
(4) Treasury note rates with terms commensurate with the remaining term of the Notes between 4.05% to 4.19%, and (5) duration of the note as an amortizing debenture ranging from
approximately 0.15 to 0.17 years, based upon present values.

14

---



The
fair value of the derivative for anti-dilution protection was valued using a standard put option binomial model, adjusted for the probability of subsequent financing at
prices below the principal's conversion option with the following inputs: (1) closing stock price as of the valuation date of $0.30 (2) exercise price equal to the $0.34 conversion price
(3) volatility between 106.64% to 201.55% based upon the Company's stock trading (4) Treasury note rates with terms commensurate with the
remaining term of the Notes between 4.05% to 4.19% and (5) duration of the note as an amortizing debenture ranging from approximately 0.15 to 0.17 years based upon present values.

The
fair value of the derivative for contractual default provisions was determined by taking the monthly amortization schedule, and multiplying the result by the contractual penalty of
120%. The present value of this penalty was then adjusted by the estimated probability of default for each valuation date.

The
fair value of the derivative asset related to the Company's right to force conversion was based upon a binomial option pricing model with the following inputs: (1) closing
stock price at the valuation date of $0.30 (2) exercise price of $0.34 per share which is required for the forced conversion (3) volatility between 106.64% to 201.55% based upon the
Company's stock trading (4) Treasury note rate with terms commensurate with the remaining term of the Notes between 4.05% to 4.19% and (5) duration of the note as an amortizing debenture
ranging from approximately 0.15 to 0.17 years based upon present values.

During
the three months ended September 30, 2007 a decrease in the fair value of the embedded derivative amounts of approximately $1,319,000 was recorded through results of
operations as a credit to Adjustment to Fair Value of Derivatives.

During
the three months ended September 30, 2007 the Company recorded approximately $400,000 as Interest Expense for amortization of discounts for original issue discount,
discount for warrant derivative, and other embedded derivatives identified above.

In
connection with this financing, we paid cash fees to a broker-dealer of $1,065,000 and issued a warrant to purchase 1,162,239 shares of Common Stock at an exercise price of $2.53 per
share. The initial fair value of the warrant was estimated at approximately $1,379,000 using the Black Scholes pricing model. The assumptions used in the Black Scholes model are as follows:
(1) dividend yield of 0%; (2) expected volatility of 64%, (3) risk-free interest rate of 3.99%, and (4) expected life of 5 years. Cash fees paid, and the
initial fair value of the warrant, have been capitalized as debt issuance costs and are being amortized over 36 months under the effective interest rate method. Interest expense for the three
months ended September 30, 2007 was approximately $110,000.

In
January 2007, the Company's Board of Directors agreed to reduce the exercise price of the warrants issued in connection with the 2005 debentures to $0.95 per share and to
reduce the conversion price of the debentures to $0.90 per share.

15

---



The Company has considered the impact of Emerging Issue Task Force statements, or EITFs 96-19Debtor's Accounting for a Modification or
Exchange of Debt Instruments, 02-4Determining Whether a Debtor's Modification or Exchange of Debt Instruments is Within the Scope of FASB No. 15, and
05-7Accounting for Modifications to conversion Options Embedded in Debt Instruments and Related Issueson the accounting treatment of the change in
conversion price of the 2005 Convertible Debentures described in the paragraph above. EITF 96-19 states that a transaction resulting in a significant change in the nature of a debt
instrument should be accounted for as an extinguishment of debt. The Company has concluded that the change in conversion price does not constitute a significant change in the nature of the debt and
that the transaction should not be treated as an extinguishment of that debt.

The
following table summarizes the 2005 Convertible Debentures and embedded derivatives outstanding at September 30, 2007:

2005 Convertible debentures at $0.90 at face

$
2,669,656Discounts on debentures:Original issue discount


(265,244
)Conversion feature derivative


(458,594
)Warrant derivative


(359,994
)Other derivatives


(17,493
)Net convertible debentures


1,568,234Embedded derivatives


407,8742005 Convertible debentures and embedded derivatives


1,976,205Less current portion


(1,976,205
)2005 Convertible debentures and embedded derivatives- long term

$
0


6. WARRANT AND OPTION DERIVATIVES

At September 30, 2007 the fair value of each instrument was computed under a Black Scholes model with the following assumptions: (1) dividend yield
of 0% (2) expected volatility of 149% (3) risk-free interest rate of approximately 4.13% and (4) expected life and exercise prices consistent with each individual
instrument. These calculations resulted in an aggregate value of derivative instruments of approximately $8,291,000. As a result, for the three months ended September, 2007 the Company recorded
approximately $1,807,000 as a credit to Adjustment to Fair Value of Derivatives.

The
Company has considered the impact of Emerging Issue Task Force statements, or EITFs 96-19Debtor's Accounting for a Modification or
Exchange of Debt Instruments, 02-4Determining Whether a Debtor's Modification or Exchange of Debt Instruments is Within the Scope of FASB No. 15, and
05-7Accounting for Modifications to conversion Options Embedded in Debt Instruments and Related Issueson the accounting treatment of the change in
conversion price of the 2005 Convertible Debentures described in the paragraph above. EITF 96-19 states that a transaction resulting in a significant change in the nature of a debt
instrument should be accounted for as an extinguishment of debt. The Company has concluded that the change in conversion price does not constitute a significant change in the nature of the debt and
that the transaction should not be treated as an extinguishment of that debt.

The
carrying value of the remaining 2005 debenture warrant derivatives at September 30, 2007 has been adjusted to reflect "fair value" of approximately $548,000 based upon a Black
Scholes calculation as follows: (1) dividend yield of 0%; (2) expected volatility of 149%, (3) risk-free interest rate of 4.03%, and (4) expected remaining life
of 2.75 years. This resulted in an additional decrease in the fair value

16

---



of
the warrant derivative liability of approximately $222,000 which was recorded through results of operations as a credit to Adjustment to Fair Value of Derivatives.

The
carrying value of the replacement warrant derivatives at September 30, 2007 has been adjusted to reflect "fair value" of approximately $3,298,000 based upon a Black Scholes
calculation as follows: (1) dividend yield of 0%; (2) expected volatility of 149%, (3) risk-free interest rate of 4.13%, and (4) expected remaining life of
4.00. This resulted in an increase in the fair value of the warrant derivative liability of approximately $1,623,000 which was recorded as a debit to Adjustment to Fair Value of Derivatives in the
results of operations for the three months ended September 30, 2007.

The
carrying value of the January 2005 financing warrant derivatives at September 30, 2007 have been adjusted to reflect fair value of approximately $574,000 based upon a
Black Scholes calculation as follows: (1) dividend yield of 0%, (2) expected volatility of 149%, (3) risk-free interest rate of 4.05%, and (4) expected
remaining life of 1.25 years. This resulted in an additional decrease in the fair value of the warrant derivative liability of approximately $614,000 which was recorded through results of
operations as a credit to Adjustment to Fair Value of Derivatives.

The
carrying value of the broker dealer warrant derivatives at September 30, 2007 have been adjusted to reflect fair value of approximately $1,196,000 based upon a Black Scholes
calculation as follows: (1) dividend yield of 0%, (2) expected volatility of 149%, (3) risk-free interest rate of 4.13%, and (4) expected remaining life of
4.00 years. This resulted in a decrease in the fair value of the warrant derivative liability of approximately $605,000 which was recorded through results of operations as a credit to
Adjustment to Fair Value of Derivatives.

The
carrying value of the remaining warrant derivatives at September 30, 2007 have been adjusted to reflect fair value of approximately $1,494,000 based upon a Black Scholes
calculation as follows: (1) dividend yield of 0%, (2) expected volatility of 149%, (3) risk-free interest rate ranging from 3.43% to 4.13%, and (4) expected
remaining life ranging from .25 years to 4.0 years. This resulted in a decrease in the fair value of the warrant derivative liability of approximately $1,413,000, which was recorded through
results of operations as a credit to Adjustments to Fair Value of Derivatives.

7. ADJUSTMENT TO FAIR VALUE OF DERIVATIVES

The following table summarizes the components of the Adjustment to Fair Value of Derivatives which were recorded as charges to results of operations in the
quarter ended September 30, 2007. The table summarizes by category of derivative liability the impact from market changes during the quarter, impact of additional investments and repricing and
exercise of certain warrants.

Impact of Repricing
08.31.07

"Market"
Fair Value Adj

Total
Fair Value
AdjustmentPIPE Hybrid instrument 9.06



(1,747,993
)
(1,747,993
)Embedded PIPE derivatives 9.05

942,749

(1,319,393
)
(376,644
)Original Warrants PIPE 9.05



(222,322
)
(222,322
)Other Warrant derivatives



(3,785,292
)
(3,785,292
)942,749

(7,075,000
)
(6,132,251
)


8. STOCKHOLDERS' EQUITY TRANSACTIONS

We are authorized to issue two classes of capital stock, to be designated, respectively, Preferred Stock and Common Stock. The total number of shares of Preferred
Stock we are authorized to issue is

17

---



50,000,000
par value $0.001 per share. The total number of shares of Common Stock we are authorized to issue is 500,000,000, par value $0.001 per share. We had no Preferred Stock outstanding as of
September 30, 2007. We had 75,465,805 shares of Common Stock outstanding as of September 30, 2007.

In
January 2007, the Company issued 300,000 warrants to purchase common stock at $0.96 per share in connection with consulting services provided during the quarter. The warrants
were valued at approximately $225,000 using the Black Scholes pricing model with the following assumptions: (1) dividend yield of 0%; (2) expected volatility of 165%,
(3) risk-free interest rate of 4.90%, and (4) expected life of 4.0 years. This warrant is classified as a warrant derivative.

In
January 2007, the Company issued 35,909 fully vested shares of Common Stock as consideration for service on the Company's Board of Directors, Audit Committee and Compensation
Committee. These shares are valued at market price on date of grant.

In
January 2007, the Company issued 515,000 share of Common Stock, valued at $407,000, to employees. These shares are fully vested at issuance and are valued at fair market proce
on date of grant.

In
February 2007, the Company issued 800,000 shares of Common Stock, valued at $608,000 based upon the closing price per share on the date of issuance, to Infigen, Inc. in
connection with the execution of a Patent Assignment Agreement. The Company recorded the $608,000 as deferred royalty fees and will amortize over an estimated useful life of 10 years.

In
April 2007, the Company issued 85,000 shares of common stock in settlement of legal fees of approximately $68,000. The shares were valued at the closing price per share on the
date of issuance.

In
September 2007, the Company issued 8,064,507 shares of common stock with a value of approximately $2,419,000 for the acquisition of Mytogen. The shares were valued at the
closing price per share on the date of issuance.

9. STOCK-BASED COMPENSATION

Stock Plans

On August 12, 2004, the Company's Board of Directors approved the establishment of the 2004 Stock Option Plan (the "2004 Stock
Plan"). Stockholder approval was received on December 13, 2004. The total number of common shares available for grant and issuance under the plan may not exceed
2,800,000 shares, subject to adjustment in the event of certain recapitalizations, reorganizations and similar transactions. Common stock purchase options may be exercisable by the payment of cash or
by other means as authorized by the Board of Directors or a committee established by the Board of Directors. At September 30, 2006, ACT had granted 2,604,000 common share purchase options under
the plan.

On
December 13, 2004, the Company's Board of Directors and stockholders approved the establishment of the 2004 Stock Option Plan II (the "2004 Stock Plan
II"). The total number of common shares available for grant and issuance under the plan may not exceed 1,301,161 shares, subject to adjustment in the event of certain
recapitalizations, reorganizations and similar transactions. Common stock
purchase options may be exercisable by the payment of cash or by other means as authorized by the Board of Directors or a committee established by the Board of Directors.

On
January 31, 2005, the Company's Board of Directors approved the establishment of the 2005 Stock Incentive Plan (the "2005 Plan"), subject to approval of our shareholders. The
total number of

18

---



common
shares available for grant and issuance under the plan may not exceed 9 million shares, plus an annual increase on the first day of each of the Company's fiscal years beginning in 2006
equal to 5% of the number of shares of our common stock outstanding on the last day of the immediately preceding fiscal year, subject to adjustment in the event of certain recapitalizations,
reorganizations and similar transactions. Common stock purchase options may be exercisable by the payment of cash or by other means as authorized by the Board of Directors or a committee established
by the Board of Directors.

Pursuant
to the 2005 Plan, on February 5, 2007, we granted 1,300,000 common stock purchase options to employees. The options granted have an exercise price of $0.76 per share, the
market price of the Company's stock on the date of grant. The options vest monthly over a period of 4 years. The fair value of the options was estimated at $953,000 using the Black Scholes
option pricing model. The assumptions used in the Black Scholes model are as follows: (1) dividend yield of 0%; (2) expected volatility of 163%, (3) risk-free interest
rate of 4.80%, and (4) expected life of 6.25 years. The fair value was treated in accordance with FAS 123(R) and is being amortized over a period of four years. Since the Company
vests options on the graded method, the fair value is amortized on a straight line basis which approximates the vesting schedule.

The
assumptions used in the Black Scholes models referred to above are based upon the following data: (1) Expected dividends on the underlying shares over the remaining term of
the option are based upon historical dividend data (2) The expected volatility of the price of the underlying shares over the expected term of the option is based upon historical share price
data (3) The expected term of the option is estimated by considering the contractual term of the option, the vesting period of the option, the employees' expected exercise behavior and the
post-vesting employee turnover rate.

|                                 |  | Shares
Available
For Grant |   | Stock Options
Outstanding |  | Price Per
Share |            | Weighted
Average
Exercise
Price |   | Weighted
Average
Life |  | Aggregate
Intrinsic
Value
|-------------------------------- |  | -------------------------- | - | ------------------------- |  | --------------- | ---------- | ------------------------------- | - | --------------------- |  | -------------------------
|Balance at December 31, 2006     |  | 478,137                    |   | 13,656,976                |  | $               | 0.05-$2.48 |                                 | $ | 0.71                  |  | 8.2 years                
|Annual increase pursuant to plan |  | 1,965,963                  |   |                          |  |                 |           |                                 |   |                      |  |                         
|Options granted                  |  | (1,300,000                 | ) | 1,300,000                 |  | $               | 0.76       |                                 | $ | 0.76                  |  | 9.8 years                
|Stock Awards                     |  | (515,000                   | ) |                           |  | $               |           |                                 | $ |                      |  |                          
|Balance at September 30, 2007    |  | 629,100                    |   | 14,956,976                |  | $               | 0.05-$2.48 |                                 | $ | 0.74                  |  | 8.2 years                

Aggregate
option activity for the 2004 and 2005 stock option plans is as follows:

As
of September 30, 2007 and December 31, 2006, there were 8,985,585 and 7,503,665 exercisable options outstanding at a weighted average exercise price per share of $0.71
and $0.61, respectively, and with a weighted average life of 8.25 years and 8.40 years respectively.

During
the period, no options were forfeited or exercised. The aggregate intrinsic value of all options vested is approximately $1.6 million. All fully vested options in the
Company are exercisable.

The
fair value of all options vested during the year ended December 2006 and the nine months ended September 30, 2007 was $522,516 and $468,755 respectively.

The
above pro forma disclosures are provided for 2005 because employee stock options were not accounted for using the fair-value method during that period.

19

---





For the three and nine months ended                        and September 30,
2007, a charge of approximately $100,000 and $370,000 respectively was recorded through results of operations
as General and Administrative and Research and Development expense related to share based compensation. These amounts were calculated using a pre-vesting forfeiture rate of 13%, based on
historical employee turnover and forfeiture data.

A
summary of the status of unvested employee stock options as of September 30, 2007 and changes during the period then ended, is presented below:

Options

Weighted
Average
Grant Date
Fair Value
Per ShareUnvested at December 31, 2006

3,416,398

$
0.22Granted

1,300,000

$
0.69Vested

(1,689,009
)
$
0.92Unvested at September 30, 2007

3,027,389

$
0.40


As
of September 30, 2007, the total remaining unrecognized compensation cost related to unvested stock options amounted to $1.0 million, which will be amortized over the
weighted-average remaining requisite service period of 4.0 years.

10. COMMITMENTS AND CONTINGENCIES

The Company entered into a lease for office and laboratory space in Massachusetts commencing December 2004 and expiring September 2012 and for
office space in California commencing November 2005 and expiring May 2008. Annual minimum lease payments are as follows:

Year 1

$
1,221,515Year 2


1,176,844Year 3


1,110,009Year 4


998,850Year 5


1,033,009


During
2005, the Company entered into a lease for laboratory equipment commencing November 29, 2005 and expiring May 31, 2008. Annual minimum lease payments are as follows:

2007


26,9602008


36,65563,615Imputed interest


(12,520
)Net asset value


51,095Less current portion


(51,095
)Long-term commitment under capital lease

$
0


Rent
expense recorded in the financial statements for the three month and nine month period ended September 30, 2007 and 2006 was approximately $852,000, $1,503,870, $160,000 and
$577,000, respectively.

We
have entered into employment contracts with certain executives and research personnel. The contracts provide for salaries, bonuses and stock option grants, along with other employee
benefits. The employment contracts generally have no set term and can be terminated by either party. There is a

20

---



provision
for payments of three months to one year of annual salary as severance if we terminate a contract without cause, along with the acceleration of certain unvested stock option grants.

11. INCOME TAXES

The Company files income tax returns in the U.S. federal jurisdiction, and various states and foreign jurisdictions. With few exceptions, the Company is no longer
subject to U.S. federal, state and local income tax examinations by tax authorities for years before 2001.

The
Company adopted the provisions of FASB Interpretation No. 48,Accounting for Uncertainty in Income Taxes("FIN 48"), on
January 1, 2007. As a result of the implementation of FIN 48, the Company reduced its net operating loss carryforward by $1,550,000. This reduction of the net operating loss carryforward
translated into a reduction of the gross deferred tax asset of $658,500, with a corresponding reduction of the valuation allowance against that deferred tax asset. Due to the offsetting effect of the
reduction of the valuation allowance, the adoption of Interpretation No. 48 had no impact on the Company's balance sheets or statements of operations.

Included
in the balance at September 30, 2007, are tax positions for which the ultimate deductibility is highly certain but for which there is uncertainty about the timing of such
deductibility. Because of the
impact of deferred tax accounting, the disallowance of the shorter deductibility period would not affect the annual effective tax rate.

As
the Company has significant net operating loss carryforwards, even if certain of the Company's tax positions were disallowed, it is not foreseen that the Company would have to pay any
taxes in the near future. Consequently, the Company does not calculate the impact of interest or penalties on amounts that might be disallowed.

12. SUBSEQUENT EVENTS

In October 2007, the Company made its monthly redemptions of convertible debentures described in Notes 4 and 5. The terms of the agreement provide for
payment in cash or stock at the company's discretion. In connection with the October redemption, the Company issued approximately 1,528,289 shares of common stock and redeemed approximately $382,072
in 2005 Notes Payable, and issued approximately 1,547,835 shares of common stock and redeemed approximately $309,567 in 2006 Notes Payable.

In
November 2007, the Company made its monthly redemptions of convertible debentures described in Notes 4 and 5. In connection with the November redemptions, the Company issued
approximately 1,307,008 shares of common stock and redeemed approximately $339,822 in 2005 Notes Payable, and issued 1,474,127 shares of common stock and redeemed approximately $309,567 in 2006 Notes
Payable.

At
September 30, 2007, approximately 146,799 and 625,700 of the shares related to the October redemption had been preliminarily issued by the transfer agent in accordance with the
terms of the 2005 and 2006 debenture agreement, respectively. Such shares are not reflected as issued and outstanding by the company prior to finalizing share and cash payments in connection with the
redemption in October 2007.

13. MYTOGEN ACQUISITION

On July 31, 2007, the Company signed an agreement and plan of merger with Mytogen, Inc. ("Mytogen"). On September 20, 2007, the Company and a newly
formed subsidiary of the Company

21

---



merged
into Mytogen to effect a reorganization of Mytogen. As a result of the merger, the Company became the owner of 100% of the outstanding shares of Mytogen. The Company anticipates issuing up to
975,410 shares of common stock (including options exercisable into shares of common stock) of Mytogen to certain key employees, which such number represents less than 10 percent (10%) of
the outstanding shares of Mytogen. In order to account for the financial treatment of the Mytogen acquisition, the Company referred to EITF 98-3. The Company evaluated among several factors the
insolvency of Mytogen prior to the transaction, the lack of an operating business, and the fact that Mytogen was a development stage business. The Company concluded that the Mytogen transaction was an
asset purchase, and not a business combination. Therefore, the pro-forma and other disclosures required by SFAS No. 141 do not apply. As a result, it was further determined that Historical
financial information would not be required to be presented.

Mytogen
is a biotechnology company that has been performing research and development since its inception. It had no revenues and was a development stage enterprise.

The
consideration paid to the Mytogen shareholders to consummate the merger was 8,064,516 shares of the Company and 1,500,000 warrants to purchase the Company's stock with an exercise
price of $0.75 per share. The purchase price was calculated as follows.

Common stock

$
2,419,355


The
common stock was valued using $0.30 per share, the closing price on the date of the merger. The warrants were valued using the Black-Scholes valuation model with the following
assumptions.

Stock value on date of grant

$
0.30Expected life in years


5 YearsStock price volatility


150%Risk free interest rate


4.35%Dividends during term


None


In
conjunction with the merger, the Company assumed certain operating liabilities of Mytogen including approximately $925,000 of accrued rent payments for the Charleston facility.

The
Company has determined that there were no marketing, customer, artistic or contract-related intangible assets acquired in this transaction. The only types of intangible assets
obtained in the acquisition were technology-based intangible assets.

Within
the category of technology-based intangible assets, the Company acquired innovations and technical advances related to a specific cell-therapy product for which
Mytogen had completed the Phase I trial necessary for approval by the United States Food and Drug Administration. The Company is now allowed to proceed with Phase II trials on this product.

There
are certain patents associated with this product, however as they relate solely to this product, they cannot be separated from the product.

Therefore,
it was determined that there were no intangible assets other than in-process research and development. The Company obtained an independent valuation of the assets
and liabilities

22

---



purchased
from Mytogen, including the in-process research and development. Based on that valuation, the following represents the aggregate assets and liabilities purchased by the Company.

In-process research & development

$
3,408,864Fixed assets


396,834Liabilities


(1,736,317
)$
2,069,381


In
accordance with SFAS No. 2, "Accounting for Research and Development Costs" and SFAS No. 141, "Business Combinations," the costs associated with in-process
research and development were recorded as expense on the date of the merger.

The
difference between the purchase price and the fair value of the net assets acquired is as follows.

Purchase price

$
2,419,355Net assets acquired


2,069,381$
349,974


As
both the fair value of the net assets assumed and the consideration given for those assets can be reliably measured, the unidentified difference between the two has been recorded as
expense on the date of the merger in accordance with SFAS No. 141, "Business Combinations."

23

---



ITEM 2.    MANAGEMENT'S DISCUSSION AND ANALYSIS OR PLAN OF OPERATION

OVERVIEW

This Quarterly Report on Form 10-QSB contains forward-looking statements that involve risks and uncertainties. We use words such as "may,"
"assumes," "forecasts," "positions," "predicts," "strategy," "will," "expects," "estimates," "anticipates," "believes," "projects," "intends," "plans," "budgets," "potential," "continue" and
variations thereof, and other statements contained in quarterly report, and the exhibits hereto, regarding matters that are not historical facts and are forward-looking statements. Because these
statements involve risks and uncertainties, as well as certain assumptions, actual results may differ materially from those expressed or implied by such forward-looking statements. Factors that could
cause actual results to differ materially include, but are not limited to risks inherent in: our early stage of development, including a lack of operating history, lack of profitable operations and
the need for additional capital; the development and commercialization of largely novel and unproven technologies and products; our ability to protect, maintain, and defend our intellectual property
rights: uncertainties regarding our ability to obtain the capital resources needed to continue research and development operations and to conduct research, preclinical development and clinical trials
necessary for regulatory approvals; uncertainty regarding the outcome of clinical trials and our overall ability to compete effectively in a highly complex, rapidly developing, capital intensive and
competitive industry. See "RISK FACTORS THAT MAY AFFECT OUR BUSINESS" set forth below on page 30 for a more complete discussion of these factors. Readers are cautioned not to place undue
reliance on these forward-looking statements, which speak only as of the date that they are made. We undertake no obligation to publicly update or revise any forward-looking statements, whether as a
result of new information, future events or otherwise.

The
following discussion should be read in conjunction with the financial statements and notes thereto included in Part I, Item 1 of this Quarterly Report on
Form 10-QSB.

We
are a biotechnology company focused on developing and commercializing human embryonic and adult stem cell technology in the emerging field of regenerative medicine.

SIGNIFICANT ACCOUNTING POLICIES

Basis of PresentationThe accompanying consolidated financial statements have been prepared in
accordance with accounting principles generally accepted in the United States of America and to the rules and regulations of the Securities and Exchange Commission for Form 10-QSB.

Principles of ConsolidationThe accounts of the Company are included in the accompanying consolidated
financial statements for the period from January 1, 2005 to November 18, 2005, when the shareholders approved the roll-up merger to combine the two companies. During the
period from January 1, 2005 to November 18, 2005, all intercompany balances and transactions were eliminated in consolidation.

Use of EstimatesThese consolidated financial statements have been prepared in accordance with
accounting principles generally accepted in the United States and, accordingly, require management to make estimates and assumptions that affect the reported amounts of assets and liabilities at the
date of the financial statements and the reported amounts of revenues and expenses during the reporting period. Specifically, our management has estimated variables used to calculate the Black Scholes
and binomial lattice model calculations used to value derivative instruments discussed below under "Valuation of Derivative Instruments". In addition, management has estimated the expected economic
life and value of our licensed technology, our net operating loss for tax purposes, share-based payments

24

---



to
compensation to employees, directors, consultants and investment banks, the useful lives of our fixed assets and our allowance for bad debts. Actual results could differ from those estimates.

ReclassificationsCertain prior year financial statement balances have been reclassified to conform to
the current year presentation. These reclassifications have no effect on the recorded net loss.

Cash and Cash EquivalentsCash equivalents are comprised of certain highly liquid investments with
maturities of three months or less when purchased. We maintain our cash in bank deposit accounts, which at times, may exceed federally insured limits. We have not experienced any losses related to
this concentration of risk.

Accounts ReceivableWe periodically assess our accounts receivable for collectibility on a specific
identification basis. If collectibility of an account becomes unlikely, we record an allowance for that doubtful account. Once we have exhausted efforts to collect, we write off the account receivable
against the allowance we have already created. We do not require collateral for our trade accounts receivable.

EquipmentWe record our equipment at historical cost. We expense maintenance and repairs as incurred.
Depreciation is provided for on the straight-line method over three to six years. Upon disposition of equipment, the gross cost and accumulated depreciation are written off and the
difference between the proceeds and the net book value is recorded as a gain or loss on sale of assets. In the case of certain assets acquired under Capital Leases, the assets are recorded net of
imputed interest, based upon the net present value of future payments. Assets under capital lease are pledged as collateral for the related lease.

Deferred Issuance CostsPayments, either in cash or share-based payments, made in connection with the
sale of debentures are recorded as deferred debt issuance costs and amortized using the effective interest method over the lives of the related debentures. The weighted average amortization period for
deferred debt issuance costs is 36 months.

Intangible and Long-Lived AssetsWe follow Statement of Financial Accounting Standards
("FAS") No. 144, "Accounting for Impairment of Disposal of Long-Lived Assets," which established a "primary asset" approach to determine the cash flow estimation period for a group
of assets and liabilities that represents the unit of accounting for a long-lived asset to be held and used. Long-lived assets to be held and used are reviewed for impairment
whenever events or changes in circumstances indicate that the carrying amount of an asset may not be recoverable. The carrying amount of a long-lived asset is not recoverable if it exceeds
the sum of the undiscounted cash flows expected to result from the use and eventual disposition of the asset. Long-lived assets to be disposed of are reported at the lower of carrying
amount or fair value less cost to sell. During the years ended December 31, 2006 and 2005, no impairment loss was recognized.

Fair Value of Financial InstrumentsFor certain of our financial instruments, including accounts
receivable, account payable, accrued expenses, interest payable, bank overdraft, advances
payable and notes payable, the carrying amounts approximate fair value due to their relatively short maturities.

Valuation of Derivative InstrumentsFAS 133, "Accounting for Derivative Instruments and Hedging
Activities" requires bifurcation of embedded derivative instruments and measurement of fair value for accounting purposes. In addition, FAS 155, "Accounting for Certain Hybrid Financial
Instruments" requires measurement of fair values of hybrid financial instruments for accounting purposes. We applied the accounting proscribed in FAS 155 to account for the 2006 Convertible
Debentures described above in Note 4Convertible Debentures2006. In determining the appropriate fair value, the Company uses a variety of valuation techniques including
Black Scholes models, Binomial Option

25

---



Pricing
models, Standard Put Option Binomial models and net present value of certain penalty amounts. Derivative liabilities are adjusted to reflect fair value at each period end, with any increase or
decrease in the fair value being recorded in results of operations as Adjustments to Fair Value of Derivatives. The effects of interactions between embedded derivatives are calculated and accounted
for in arriving at the overall fair value of the financial instruments. In addition, the fair values of freestanding derivative instruments such as warrant derivatives are valued using Black Scholes
models.

Revenue RecognitionOur revenues are generated from license and research agreements with
collaborators. Licensing revenue is recognized on a straight-line basis over the shorter of the life of the license or the estimated economic life of the patents related to the license.
Deferred revenue represents the portion of the license and other payments received that has not been earned. Costs associated with the license revenue are deferred and recognized over same term as the
revenue. Reimbursements of research expense pursuant to grants are recorded in the period during which collection of the reimbursement becomes assured, because the reimbursements are subject to
approval.

Research and Development CostsResearch and development costs consist of expenditures for the research
and development of patents and technology, which are not capitalizable. Our research and development costs consist mainly of payroll and payroll related expenses, research supplies and research
grants. Reimbursements of research expense pursuant to grants are recorded in the period during which collection of the reimbursement becomes assured, because the reimbursements are subject to
approval. Research and development costs are expensed as incurred.

Stock Based CompensationAt September 30, 2007 we had two stock-based employee compensation
plans, which are described more fully in Note 9Stock Based Compensation.

Prior
to the January 1, 2006 adoption of the FAS No. 123(R), "Share-Based Payment," the Company accounted for stock-based compensation using the intrinsic value method
prescribed in Accounting Principles Board ("APB") Opinion No. 25, "Accounting for Stock Issued to Employees," and related interpretations. Because the stock option grant price equaled the
market price on the date of grant, no compensation expense was recognized by the Company for stock-based compensation. As permitted by SFAS No. 123, "Accounting for Stock-Based Compensation"
("SFAS 123") stock-based compensation was included as a pro forma disclosure in the notes to the consolidated financial statements.

Effective
January 1, 2006, the Company adopted the fair value recognition provisions of SFAS 123R, using the modified prospective transition method. Under this transition
method, stock-based compensation expense is recognized in the consolidated financial statements for granted, modified or settled stock options based on estimated fair values. Results for prior periods
have not been restated, as provided for under the modified prospective transition method.

Prior
to the adoption of SFAS 123R, the Company presented all tax benefits resulting from the exercise of stock options as operating cash inflows in the consolidated statements of
cash flows, in accordance with the provisions of the Emerging Issues Task Force ("EITF") Issue No. 00-15, "Classification in the Statement of Cash Flows of the Income Tax Benefit
Received by a Company upon Exercise of a Nonqualified Employee Stock Option." SFAS 123R requires the benefits of tax deductions in excess of the compensation cost recognized for those options
to be classified as financing cash inflows rather than operating cash inflows, on a prospective basis. The impact of this change was not material to the Company.

26

---



Net Loss Per ShareWe use FAS No. 128, "Earnings Per Share" for calculating the basic and
diluted loss per share. We compute basic loss per share by dividing net loss and net loss attributable to common shareholders by the weighted average number of common shares outstanding. Diluted loss
per share is computed similar to basic loss per share except that the denominator is increased to include the number of additional common shares that would have been outstanding if the potential
shares had been issued and if the additional shares were dilutive. Common equivalent shares are excluded from the computation of net loss per share if their effect is anti-dilutive.

For
the three months ended September 30, 2007, approximately 58,000,000 potentially dilutive shares were excluded from the shares used to calculate diluted earnings per share as
their inclusion would be anti-dilutive. There were 23,000,000 potentially dilutive shares at September 30, 2006.

Concentrations and Other RisksCurrently, the Company's revenues and accounts receivable are
concentrated on one customer. There is also a geographic concentration of the Company's primary activities in Northern California and Massachusetts. Other risks include the uncertainty of the
regulatory environment and the effect of future regulations on the Company's business activities. As we are a biotechnology research and development company, there is also the attendant risk that
someone could commence legal proceedings over our discoveries. Acts of God could also adversely affect our business.

Income TaxesDeferred income taxes are provided using the liability method whereby deferred tax assets
are recognized for deductible temporary differences and operating loss and tax credit carryforwards and deferred tax liabilities are recognized for taxable temporary differences. Temporary differences
are the differences between the reported amounts of assets and liabilities and their tax bases. Deferred tax assets are reduced by a valuation allowance when, in the opinion of management, it is more
likely than not that some portion or all of the deferred tax assets will not be realized. Deferred tax assets and liabilities are adjusted for the effects of the changes in tax laws and rates of the
date of enactment.

When
tax returns are filed, it is highly certain that some positions taken would be sustained upon examination by the taxing authorities, while others are subject to uncertainty about
the merits of the position taken or the amount of the position that would be ultimately sustained. The benefit of a tax position is recognized in the financial statements in the period during which,
based on all available evidence, management believes it is more likely than not that the position will be sustained upon examination, including the resolution of appeals or litigation processes, if
any. Tax positions taken are not offset or aggregated with other positions. Tax positions that meet the more-likely-than-not recognition threshold are measured as
the largest amount of tax benefit that is more than 50 percent likely of being realized upon
settlement with the applicable taxing authority. The portion of the benefits associated with tax positions taken that exceeds the amount measured as described above is reflected as a liability for
unrecognized tax benefits in the accompanying balance sheet or a reduction in deferred tax amounts along with any associated interest and penalties that would be payable to the taxing authorities upon
examination.

Interest
and penalties associated with unrecognized tax benefits are classified as additional income taxes in the statement of income.

Recent Accounting Pronouncements

On February 15, 2007, the Financial Accounting Standards Board, or FASB, issued FAS No. 159, "The Fair Value Option for Financial Assets and
LiabilitiesIncluding an Amendment of FAS 115." This standard permits an entity to choose to measure many financial instruments and certain other items at fair value. This option is
available to all entities. Most of the provisions in FAS 159 are elective; however, an amendment to FAS 115 "Accounting for Certain Investments in Debt and Equity Securities" applies to
all entities with available for sale or trading securities. Some requirements apply

27

---



differently
to entities that do not report net income. FAS 159 is effective as of the beginning of an entities first fiscal year that begins after November 15, 2007. Early adoption is
permitted as of the beginning of the previous fiscal year provided that the entity makes that choice in the first 120 days of that fiscal year and also elects to apply the provisions of
FAS 157 "Fair Value Measurements." We will adopt FAS 159 beginning January 1, 2008 and we are currently evaluating the potential impact the adoption of this pronouncement will
have on our financial statements.

Effective
January 1, 2007, Advanced Cell Technology adopted FSP No. FIN 48-1, "Definition of Settlement in FASB Interpretation No. 48," (FSP FIN
48-1), which was issued on May 2, 2007. FSP FIN 48-1 amends FIN 48 to provide guidance on how an entity should determine whether a tax position is effectively settled
for the purpose of recognizing previously unrecognized tax benefits. The term "effectively settled" replaces the term "ultimately settled" when used to describe recognition, and the terms "settlement"
or "settled" replace the terms "ultimate settlement" or "ultimately settled" when used to describe measurement of a tax position under FIN 48. FSP FIN 48-1 clarifies that a tax position
can be effectively settled upon the completion of an examination by a taxing authority without being legally extinguished. For tax positions considered effectively settled, an entity would recognize
the full amount of tax benefit, even if the tax position is not considered more likely than not to be sustained based solely on the basis of its technical merits and the statute of limitations remains
open. The adoption of FSP FIN 48-1 did not have an impact on the accompanying Financial Statements.

RESULTS OF OPERATIONS

Revenues

Revenues for the three and nine months ended September 30, 2007 and 2006 were approximately $124,000, $523,000, $129,000, and $333,000 respectively. These
amounts relate primarily to license fees and royalties collected that are being amortized over the period of the license granted. The increase in revenue in current periods was due to new licenses
being granted.

Research and Development Expenses and Grant Reimbursements

Research and development expenses for the three and nine months ended September 30, 2007 and 2006 were approximately $2,987,000, $9,465,350, $2,586,000,
and $7,012,000, respectively. The increase in expenses in the current periods, which consist mainly of facility costs, payroll and payroll related expenses, research supplies and costs incurred in
connection with specific research grants, relate principally to increased staffing and spending for scientific research.

Our
research and development expenses consist primarily of costs associated with basic and pre-clinical research exclusively in the field of human stem cell therapies and
regenerative medicine, with focus on development of our technologies in cellular reprogramming, reduced complexity applications, and stem cell differentiation. These expenses represent both
pre-clinical development costs and costs associated with non-clinical support activities such as quality control and regulatory processes. The cost of our research and
development personnel is the most significant category of expense; however, we also incur expenses with third parties, including license agreements, sponsored research programs and consulting
expenses.

We
do not segregate research and development costs by project because our research is focused exclusively on stem cell therapies as a unitary field of study. Although we have three
principal areas of focus for our research, these areas are completely intertwined and have not yet matured to the point where they are separate and distinct projects. The intellectual property,
scientists and other resources dedicated to these efforts are not separately allocated to individual projects, but rather are conducting our research on an integrated basis.

28

---



We
expect that research and development expenses will continue to increase in the foreseeable future as we add personnel, expand our pre-clinical research, begin clinical
trial activities, and increase our regulatory compliance capabilities. The amount of these increases is difficult to predict due to the uncertainty inherent in the timing and extent of progress in our
research programs, and initiation of clinical trials. In addition, the results from our basic research and pre-clinical trials, as well as the results of trials of similar therapeutics
under development by others, will influence the number, size and duration of planned and unplanned trials. As our research efforts mature, we will continue to review the direction of our research
based on an assessment of the value of possible commercial applications emerging from these efforts. Based on this continuing review, we expect to establish discrete research programs and evaluate the
cost and potential for cash inflows from commercializing products, partnering with others in the biotechnology or pharmaceutical industry, or licensing the technologies associated with these programs
to third parties.

We
believe that it is not possible at this stage to provide a meaningful estimate of the total cost to complete our ongoing projects and bring any proposed products to market. The use of
human embryonic stem cells as a therapy is an emerging area of medicine, and it is not known what clinical trials will be required by the FDA in order to gain marketing approval. Costs to complete
could vary substantially depending upon the projects selected for development, the number of clinical trials required and the number of patients needed for each study. It is possible that the
completion of these studies could be delayed for a variety of reasons, including difficulties in enrolling patients, delays in manufacturing, incomplete or inconsistent data from the
pre-clinical or clinical trials, and difficulties evaluating the trial results. Any delay in completion of a trial would increase the cost of that trial, which would harm our results of
operations. Due to these uncertainties, we cannot reasonably estimate the size, nature nor timing of the costs to complete, or the amount or timing of the net cash inflows from our current activities.
Until we obtain further relevant pre-clinical and clinical data, we will not be able to estimate our future expenses related to these programs or when, if ever, and to what extent we will
receive cash inflows from resulting products.

Grant
reimbursements for the three and nine months ended September 30, 2007 and 2006 were approximately $0, $67,000, $6,000 and $369,000 respectively. The 2006 amounts represent
approved reimbursements pursuant the grant from National Institutes of Science and Technology. This grant expired in May 2006. The 2007 grant amount is from the Small Business Technology
Transfer Program.

General and Administrative Expenses

General and administrative expenses for the three and nine months ended September 30, 2007 and 2006 were approximately $1,618,000, $4,605,000, $1,337,000
and $5,845,000 respectively. Expenses for the three month period versus the same period last year have decreased primarily as a result of decreased general and administrative infrastructure costs and
legal fees.

Other Income (Expense)

Other income (expense) for the three and nine months ended September 30, 2007 and 2006 were approximately $174,000, $583,000, $(26,758,000) and
$(4,130,000), respectively. The increase in other expense in the three months ended September 30, 2007, compared to other income in the prior periods, relates primarily to adjustments to fair
value of derivatives related to the Convertible Debenture financing and the charges related to issuance of Convertible Debentures. The increase in interest expense in the nine months ended
September 2007, compared to interest expense in the prior periods relates primarily to interest recorded in connection with the convertible debentures.

29

---



Net Income (Loss)

Net income (loss) for the three and nine months ended September 30, 2007and 2006 was approximately $(8,151,000), $(16,913,000), $(30,614,000), and
$(16,506,000) respectively. The decrease in loss in the current period is the result of changes to the fair value of derivatives, interest charges related to convertible debentures and charges related
to issuance of Convertible Debentures along with increased general and administrative and research and development expenses, as well as decreased grant reimbursements.

LIQUIDITY AND CAPITAL RESOURCES

We are financing our operations primarily with $10,000,000 of proceeds of convertible debentures issued in August, 2007 and described in our Current Report on
Form 8-K filed with the Securities and Exchange Commission and above in Note 3Convertible Debentures 2007.
To a substantially lesser degree, financing of our operations is provided through grant funding, payments received under license agreements, and interest earned on cash and cash equivalents.

With
the exception of 2002, when we sold certain assets of a subsidiary resulting in a gain for the year, we have incurred substantial net losses each year since inception as a result of
research and development and general and administrative expenses in support of our operations. We anticipate incurring substantial net losses in the future.

Cash
and cash equivalents at September 30, 2007 and December 31, 2006 were approximately $6,683,000 and $8,689,000, respectively. The decrease in the current period is
primarily the result of operational cash expenditures.

Our
cash and cash equivalents are limited. We expect to require substantial additional funding. Our future cash requirements will depend on many factors, including the pace and scope of
our research and development programs, the costs involved in filing, prosecuting, maintaining and enforcing patents and other costs associated with commercializing our potential products. We intend to
seek additional funding primarily through public or private financing transactions, and, to a lesser degree, new licensing or scientific collaborations, grants from governmental or other institutions,
and other related transactions. If we are unable to raise additional funds, we will be forced to either scale back our business efforts or curtail our business activities entirely. We anticipate that
our available cash and expected income will be sufficient to finance most of our current activities for at least twelve months from the date of the financial statements, although certain of these
activities and related personnel may need to be reduced. We cannot assure you that public or private financing or grants will be available on acceptable terms, if at all. Several factors will affect
our ability to raise additional funding, including, but not limited to, the volatility of our Common Stock.

30

---





RISK FACTORS THAT MAY AFFECT OUR BUSINESS

Our business is subject to various risks, included but not limited to those described below. You should carefully consider these factors,
together with all the other information disclosed in this Quarterly Report on Form 10-QSB. Any of these risks could materially adversely affect our business, operating results and
financial condition.

Risks Relating to Our Early Stage of Development

We have a limited operating history on which potential investors may evaluate our operations and prospects for profitable
operations.We have a limited operating history on which a potential investor may base an evaluation of us and our prospects. If we are unable to begin and sustain
profitable operations, investors may lose their entire investment in us. Our human embryonic stem cell programs are in the pre-clinical stage, and our adult stem cell myoblast program has
completed Phase I and Ib Food and Drug Administration, or FDA, clinical trials. Our prospects must be considered speculative in light of the risks, expenses and difficulties frequently encountered by
companies in their early stages of development, particularly in light of the uncertainties relating to the new, competitive and rapidly evolving markets in which we anticipate we will operate. To
attempt to address these risks, we must, among other things, further develop our technologies, products and services, successfully implement our research, development, marketing and commercialization
strategies, respond to competitive developments and attract, retain and motivate qualified personnel. A substantial risk is involved in investing in us because, as an early stage company,



These
difficulties are compounded by our heavy dependence on emerging and sometimes unproven technologies. In addition, some of our significant potential revenue sources involve
ethically sensitive and controversial issues which could become the subject of legislation or regulations that could materially restrict our operations and, therefore, harm our financial condition,
operating results and prospects for bringing our investors a return on their investment.

We have a history of operating losses, and we cannot assure you that we will achieve future revenues or operating profits.We
have generated modest revenue to date from our operations. Historically, we have had net operating losses each year since our inception. We have limited current potential sources of revenue from
license fees and product development revenues, and we cannot assure you that we will be able to develop such revenue sources or that our operations will become profitable, even if we are able to
commercialize our technologies or any products or services developed from those technologies. If we continue to suffer losses as we have in the past, investors may not receive any return on their
investment and may lose their entire investment.

Although
we have revenues from license fees and royalties, we have no commercially marketable products and no immediate ability to generate revenue from commercial products, nor any
assurance of being able to develop our technologies for commercial applications. As a result, we may never be able to operate profitably. We are just beginning to identify products available for
pre-clinical trials and may not receive significant revenues from commercial sales of our products for the next several years, if at all, although we do generate revenues from licensing
activities. We have marketed only a limited amount of services based on our technologies and have little experience in doing so. Our technologies and any potential products or services that we may
develop will require significant additional effort and investment prior to material commercialization and, in the case of any biomedical products, pre-clinical and clinical testing and
regulatory approvals. We cannot assure you that we will be able to develop any

31

---



such
technologies or any products or services, or that such technologies, products or services will prove to be safe and efficacious in clinical trials, meet applicable regulatory standards, be
capable of being produced in commercial quantities at acceptable costs or be successfully marketed. For that reason, we may not be able to generate revenues from commercial production or operate
profitably.

We
have sold the agricultural portion of our business in order to finance operations. The agricultural applications of our technology generally have a more rapid realization of revenues
due to more limited regulatory requirements and testing. Our ability to generate revenue from any agricultural applications of our technology is limited to existing license royalties, if any.

We will require substantial additional funds to continue operating which may not be available on acceptable terms, if at
all.We have losses from operations, negative cash flows from operations and a substantial stockholders' deficit that raise substantial doubt about our ability to
continue as a going concern. We do not believe that our cash from all sources, including cash, cash equivalents and anticipated revenue stream from licensing fees and sponsored research contracts is
sufficient for us to continue operations beyond June 30, 2008 without raising additional financing.

Management
continues to evaluate alternatives and sources for additional funding, which may include public or private investors, strategic partners, and grant programs available through
specific states or foundations, although there is no assurance that such sources will result in raising additional capital. Lack of necessary funds may require us to delay, scale back or eliminate
some or all of our research and product development programs and/or our capital expenditures, to license our potential products or technologies to third parties, to consider business combinations
related to ongoing business operations, or shut down some, or all, of our operations.

In
addition, our cash requirements may vary materially from those now planned because of results of research and development, potential relationships with strategic partners, changes in
the focus and direction of our research and development programs, competition, litigation required to protect our technology, technological advances, the cost of pre-clinical and clinical
testing, the regulatory process of the FDA, and foreign regulators, whether any of our products become approved or the market acceptance of any such products and other factors. Our current cash
reserves are not sufficient to fund our operations through the commercialization of our first products or services.

We have limited clinical testing, regulatory, manufacturing, marketing, distribution and sales capabilities which may limit our ability to generate
revenues.Because of the relatively early stage of our research and development programs, we have not yet invested significantly in regulatory, manufacturing,
marketing, distribution or product sales resources. We cannot assure you that we will be able to develop any such resources successfully or as quickly as may be necessary. The inability to do so may
harm our ability to generate revenues or operate profitably.

Risks Relating to Competition

Our competition includes both public and private organizations and collaborations among academic institutions and large pharmaceutical companies, most of which
have significantly greater experience and financial resources than we do.The biotechnology and pharmaceutical industries are characterized by intense competition.
We compete against numerous companies, both domestic and foreign, many of which have substantially greater experience and financial and other resources than we have. Several such enterprises have
initiated cell therapy research programs and/or efforts to treat the same diseases targeted by us. Companies such as Geron Corporation, Genzyme Corporation, StemCells, Inc., Aastrom
Biosciences, Inc. and Viacell, Inc., as well as others, many of which have substantially greater resources and experience in our fields than we do, are well situated to effectively
compete with us. Any of the world's largest pharmaceutical companies represents a significant actual or potential competitor with vastly greater resources than ours.

32

---



These
companies hold licenses to genetic selection technologies and other technologies that are competitive with our technologies. These and other competitive enterprises have devoted,
and will continue to devote, substantial resources to the development of technologies and products in competition with us.

Private
and public academic and research institutions also compete with us in the research and development of therapeutic products based on human embryonic and adult stem cell
technologies. In the past several years, the pharmaceutical industry has selectively entered into collaborations with both public and private organizations to explore the possibilities that stem cell
therapies may present for substantive breakthroughs in the fight against disease.

In
addition, many of our competitors have significantly greater experience than we have in the development, pre-clinical testing and human clinical trials of biotechnology
and pharmaceutical products, in obtaining FDA and other regulatory approvals of such products and in manufacturing and marketing such products. Accordingly our competitors may succeed in obtaining FDA
approval for products more rapidly or effectively than we can. Our competitors may also be the first to discover and obtain a valid patent to a particular stem cell technology which may effectively
block all others from doing so. It will be important for us or our collaborators to be the first to discover any stem cell technology that we are seeking to discover. Failure to be the first could
prevent us from commercializing all of our research and development affected by that discovery. Additionally, if we commence commercial sales of any products, we will also be competing with respect to
manufacturing efficiency and sales and marketing capabilities, areas in which we have no experience.

The
United States is encountering tremendous competition from many foreign countries that are providing an environment more attractive for stem cell research. The governments of numerous
foreign countries are investing in stem cell research, providing facilities, personnel and legal environments intended to attract biotechnology companies and encourage stem cell research and
development of stem cell-related technologies.

These
efforts by foreign countries may make it more difficult to effectively compete in our industry and may generate competitors with substantially greater resources than ours.

Risks Relating to Our Technology

We rely on nuclear transfer and embryonic stem cell technologies that we may not be able to successfully develop, which will prevent us from generating revenues,
operating profitably or providing investors any return on their investment.We have concentrated our research on our nuclear transfer, embryonic stem cell and
myoblast technologies, and our ability to operate profitably will depend on being able to successfully develop these technologies for human applications. These are emerging technologies with, as yet,
limited human applications. We cannot guarantee that we will be able to successfully develop our nuclear transfer, embryonic stem cell or myoblast technologies or that such development will result in
products or services with any significant commercial utility. We anticipate that the commercial sale of such products or services, and royalty/licensing fees related to our technology, would be our
primary sources of revenues. If we are unable to develop our technologies, investors will likely lose their entire investment in us.

The
outcome of pre-clinical, clinical and product testing of our products is uncertain, and if we are unable to satisfactorily complete such testing, or if such testing
yields unsatisfactory results, we will be unable to commercially produce our proposed products. Before obtaining regulatory approvals for the commercial sale of any potential human products, our
products will be subjected to extensive pre-clinical and clinical testing to demonstrate their safety and efficacy in humans. We cannot assure you that the clinical trials of our products,
or those of our licensees or collaborators, will demonstrate the safety and efficacy of such products at all, or to the extent necessary to obtain appropriate regulatory approvals, or that the testing
of such products will be completed in a timely manner, if at all,

33

---



or
without significant increases in costs, program delays or both, all of which could harm our ability to generate revenues. In addition, our prospective products may not prove to be more effective
for treating disease or injury than current therapies. Accordingly, we may have to delay or abandon efforts to research, develop or obtain regulatory approval to market our prospective products. Many
companies involved in biotechnology research and development have suffered significant setbacks in advanced clinical trials, even after promising results in earlier trials. The failure to adequately
demonstrate the safety and efficacy of a therapeutic product under development could delay or prevent regulatory approval of the product and could harm our ability to generate revenues, operate
profitably or produce any return on an investment in us.

While
the marketing of cloned or transgenic animals does not currently require regulatory approval, such approval may be required in the future. We cannot assure you that we would obtain
such approvals or that our licensees' products would be accepted in the marketplace. This lack of approval could reduce or preclude any royalty revenues we might receive from our licensees in that
field.

We may not be able to commercially develop our technologies and proposed product lines, which, in turn, would significantly harm our ability to earn revenues and
result in a loss of investment.Our ability to commercially develop our technologies will be dictated in large part by forces outside our control which cannot be
predicted, including, but not limited to, general economic conditions, the success of our research and pre-clinical and field testing, the availability of collaborative partners to finance
our work in pursuing applications of nuclear transfer technology and technological or other developments in the biomedical field which, due to efficiencies, technological breakthroughs or greater
acceptance in the biomedical industry, may render one or more areas of commercialization more attractive, obsolete or competitively unattractive. It is possible that one or more areas of
commercialization will not be pursued at all if a collaborative partner or entity willing to fund research and development cannot be located. Our decisions regarding the ultimate products and/or
services we pursue could have a significant adverse affect on our ability to earn revenue if we misinterpret trends, underestimate development costs and/or pursue wrong products or services. Any of
these factors either alone or in concert could materially harm our ability to earn revenues and could result in a loss of any investment in us.

If we are unable to keep up with rapid technological changes in our field or compete effectively, we will be unable to operate
profitably.We are engaged in activities in the biotechnology field, which is characterized by extensive research efforts and rapid technological progress. If we
fail to anticipate or respond adequately to technological developments, our ability to operate profitably could suffer. We cannot assure you that research and discoveries by other biotechnology,
agricultural, pharmaceutical or other companies will not render our technologies or potential products or services uneconomical or result in products superior to those we develop or that any
technologies, products or services we develop will be preferred to any existing or newly-developed technologies, products or services.

We may not be able to protect our proprietary technology, which could harm our ability to operate profitably.The
biotechnology and pharmaceutical industries place considerable importance on obtaining patent and trade secret protection for new technologies, products and processes. Our success will depend, to a
substantial degree, on our ability to obtain and enforce patent protection for our products, preserve any trade secrets and operate without infringing the proprietary rights of others. We cannot
assure you that:



34

---





We
are aware of certain patents that have been granted to others and certain patent applications that have been filed by others with respect to nuclear transfer technologies. The fields
in which we operate have been characterized by significant efforts by competitors to establish dominant or blocking patent rights to gain a competitive advantage, and by considerable differences of
opinion as to the value and legal legitimacy of competitors' purported patent rights and the technologies they actually utilize in their businesses.

Our business is highly dependent upon maintaining licenses with respect to key technology.Several of the key patents we
utilize are licensed to us by third parties. These licenses are subject to termination under certain circumstances (including, for example, our failure to make minimum royalty payments or to timely
achieve development and commercialization benchmarks). The loss of any of such licenses, or the conversion of such licenses to non-exclusive licenses, could harm our operations and/or
enhance the prospects of our competitors.

Certain
of these licenses also contain restrictions, such as limitations on our ability to grant sublicenses that could materially interfere with our ability to generate revenue through
the licensing or sale to third parties of important and valuable technologies that we have, for strategic reasons, elected not to pursue directly. The possibility exists that in the future we will
require further licenses to complete and/or commercialize our proposed products. We cannot assure you that we will be able to acquire any such licenses on a commercially viable basis.

We may not be able to adequately protect against piracy of intellectual property in foreign jurisdictions.Considerable
research in the areas of stem cells, cell therapeutics and regenerative medicine is being performed in countries outside of the United States, and a number of our competitors are located in those
countries. The laws protecting intellectual property in some of those
countries may not provide protection for our trade secrets and intellectual property adequate to prevent our competitors from misappropriating our trade secrets or intellectual property. If our trade
secrets or intellectual property are misappropriated in those countries, we may be without adequate remedies to address the issue.

Certain of our technology is not protectable by patent.Certain parts of our know-how and technology are not
patentable. To protect our proprietary position in such know-how and technology, we intend to require all employees, consultants, advisors and collaborators to enter into confidentiality
and invention ownership agreements with us. We cannot assure you, however, that these agreements will provide meaningful protection for our trade secrets, know-how or other proprietary
information in the event of any unauthorized use or disclosure. Further, in the absence of patent protection, competitors who independently develop substantially equivalent technology may harm our
business.

Patent litigation presents an ongoing threat to our business with respect to both outcomes and costs.We have previously
been involved in patent interference litigation, and it is possible that further litigation over patent matters with one or more competitors could arise. We could incur substantial litigation or
interference costs in defending ourselves against suits brought against us or in suits in which we may assert our patents against others. If the outcome of any such litigation is unfavorable, our
business could be materially adversely affected. To determine the priority of inventions, we may also have to participate in interference proceedings declared by the United States Patent and Trademark
Office, which could result in substantial cost to us. Without additional capital, we may not have the resources to adequately defend or pursue this litigation.

35

---



Risks Related to Product Development

Limited experience in conducting and managing preclinical development activities, clinical trials and the application process necessary to obtain regulatory
approvals.Our limited experience in conducting and managing preclinical development activities, clinical trials and the application process necessary to obtain
regulatory approvals might prevent us from successfully designing or implementing a preclinical study or clinical trial. If we do not succeed in conducting and managing our preclinical development
activities or clinical trials, or in obtaining regulatory approvals, we might not be able to commercialize our product candidates, or might be significantly delayed in doing so, which will materially
harm our business.

None
of the products that we are currently developing has been approved by the FDA or any similar regulatory authority in any foreign country. Our ability to generate revenues from any
of our product candidates will depend on a number of factors, including our ability to successfully complete clinical trials, obtain necessary regulatory approvals and implement our commercialization
strategy. In addition, even if we are successful in obtaining necessary regulatory approvals and bringing one or more product candidates to market, we will be subject to the risk that the marketplace
will not accept those products. We may, and anticipate that we will need to, transition from a company with a research and development focus to a company capable of supporting commercial activities
and we may not succeed in such a transition.

Because
of the numerous risks and uncertainties associated with our product development and commercialization efforts, we are unable to predict the extent of our future losses or when or
if we will become profitable. Our failure to successfully commercialize our product candidates or to become and remain profitable could depress the market price of our common stock and impair our
ability to raise capital, expand our business, diversify our product offerings and continue our operations.

Our approach of using cell-based therapy for the treatment of heart damage is risky and unproven and no products using this approach have received
regulatory approval in the United States or Europe.We believe that no company has yet been successful in its efforts to obtain regulatory approval in the United
States or Europe of a cell-based therapy product for the treatment of heart disease in humans. Cell-based therapy products, in general, may be susceptible to various risks,
including undesirable and unintended side effects, unintended immune system responses, inadequate therapeutic efficacy or other characteristics that may prevent or limit their approval by regulators
or commercial use. Many companies in the industry have suffered significant setbacks in advanced clinical trials, despite promising results in earlier trials.

If our clinical trials are unsuccessful or significantly delayed, or if we do not complete our clinical trials, we will not receive regulatory approval for or be
able to commercialize our product candidates.Our lead product candidate, our myoblast program, is still in clinical testing and has not yet received approval
from the FDA or any similar foreign regulatory authority for any indication. Although this product candidate has received positive results in Phase I and Ib clinical trials, it may never receive
regulatory approval or be commercialized in the United States or other countries.

We
cannot market any product candidate until regulatory agencies grant approval or licensure. In order to obtain regulatory approval for the sale of any product candidate, we must, among
other requirements, provide the FDA and similar foreign regulatory authorities with preclinical and clinical data that demonstrate to the satisfaction of regulatory authorities that our product
candidates are safe and effective for each indication under the applicable standards relating to such product candidate. The preclinical studies and clinical trials of any product candidates must
comply with the regulations of the FDA and other governmental authorities in the United States and similar agencies in other countries.

Even
though we have achieved positive interim results in clinical trials, these results do not necessarily predict final results, and positive results in early trials may not be
indicative of success in

36

---



later
trials. For example, our myoblast program has been studied in a limited number of patients to date. Even though our early data has been promising, we have not yet completed any large-scale
pivotal trials to establish the safety and efficacy of this therapy. There is a risk that safety concerns relating to our product candidates or cell-based therapies in general will result
in the suspension or termination of our clinical trials.

We
may experience numerous unforeseen events during, or as a result of, the clinical trial process that could delay or prevent regulatory approval and/or commercialization of our product
candidates, including the following:



We depend on third parties to assist us in the conduct of our preclinical studies and clinical trials, and any failure of those parties to fulfill their
obligations could result in costs and delays and prevent us from obtaining regulatory approval or successfully commercializing our product candidates on a timely basis, if at
all.We engage consultants and contract research organizations to help design, and to assist us in conducting, our preclinical studies and clinical trials and to
collect and analyze data from those studies and trials. The consultants and contract research organizations we engage interact with clinical investigators to enroll patients in our clinical trials. As
a result, we depend on these consultants and contract research organizations to perform the studies and trials in accordance with the investigational plan and protocol for each product candidate and
in compliance with regulations and standards, commonly referred to as "good clinical practice", for conducting, recording and reporting results of clinical trials to assure that the data and results
are credible and accurate and the trial participants are adequately protected, as required by the FDA and foreign regulatory agencies. We may face delays in our regulatory approval process if these
parties do not perform their obligations in a timely or competent fashion or if we are forced to change service providers.

37

---



We must comply with extensive government regulations in order to obtain and maintain marketing approval for our products in the United States and abroad. If we do
not obtain regulatory approval for our product candidates, we may be forced to cease our operations.Our product candidates are subject to extensive regulation in
the United States and in every other country where they will be tested or used. These regulations are wide-ranging and govern, among other things:



We
cannot market our product candidates until we receive regulatory approval. The process of obtaining regulatory approval is lengthy, expensive and uncertain. Any difficulties that we
encounter in obtaining regulatory approval may have a substantial adverse impact on our business and cause our stock price to significantly decline.

In
the United States, the FDA imposes substantial requirements on the introduction of biological products and many medical devices through lengthy and detailed laboratory and clinical
testing procedures, sampling activities and other costly and time-consuming procedures. Satisfaction of these requirements typically takes several years and the time required to do so may
vary substantially based upon the type and complexity of the biological product or medical device.

In
addition, product candidates that we believe should be classified as medical devices for purposes of the FDA regulatory pathway may be determined by the FDA to be biologic products
subject to the satisfaction of significantly more stringent requirements for FDA approval.

The
requirements governing the conduct of clinical trials and cell culturing and marketing of our product candidates outside the United States vary widely from country to country.
Foreign approvals may take longer to obtain than FDA approvals and can require, among other things, additional testing and different clinical trial designs. Foreign regulatory approval processes
generally include all of the risks associated with the FDA approval processes. Some foreign regulatory agencies also must approve prices of the products. Regulatory approval in one country does not
ensure regulatory approval in another, but a failure or delay in obtaining regulatory approval in one country may negatively impact the regulatory process in others. We may not be able to file for
regulatory approvals and may not receive necessary approvals to market our product candidates in any foreign country. If we fail to comply with these regulatory requirements or fail to obtain and
maintain required approvals in any foreign country, we will not be able to sell our product candidates in that country and our ability to generate revenue will be adversely affected.

We
cannot assure you that we will obtain FDA or foreign regulatory approval to market any of our product candidates for any indication in a timely manner or at all. If we fail to obtain
regulatory approval of any of our product candidates for at least one indication, we will not be permitted to market our product candidates and may be forced to cease our operations.

38

---



Even if some of our product candidates receive regulatory approval, these approvals may be subject to conditions, and we and our third party
manufacturers will in
any event be subject to significant ongoing regulatory obligations and oversight.Even if any of our product candidates receives regulatory approval, the
manufacturing, marketing and sale of our product candidates will be subject to stringent and ongoing government regulation. Conditions of approval, such as limiting the category of patients who can
use the product, may significantly impact our ability to commercialize the product and may make it difficult or impossible for us to market a product profitably. Changes we may desire to make to an
approved product, such as cell culturing changes or revised labeling, may require further regulatory review and approval, which could prevent us from updating or otherwise changing an approved
product. If our product candidates are approved by the FDA or other regulatory authorities for the treatment of any indications, regulatory labeling may specify that our product candidates be used in
conjunction with other therapies.

Once
obtained, regulatory approvals may be withdrawn for a number of reasons, including the later discovery of previously unknown problems with the product. Regulatory approval may also
require costly post-marketing follow-up studies, and failure of our product candidates to demonstrate sufficient efficacy and safety in these studies may result in either
withdrawal of marketing approval or severe limitations on permitted product usage. In addition, numerous additional regulatory requirements relating to, among other processes, the labeling, packaging,
adverse event reporting, storage, advertising, promotion and record-keeping will also apply. Furthermore, regulatory agencies subject a marketed product, its manufacturer and the manufacturer's
facilities to continual review and periodic inspections. Compliance with these regulatory requirements are time consuming and require the expenditure of substantial resources.

If
any of our product candidates is approved, we will be required to report certain adverse events involving our products to the FDA, to provide updated safety and efficacy information
and to comply with requirements concerning the advertisement and promotional labeling of our products. As a result, even if we obtain necessary regulatory approvals to market our product candidates
for any indication, any adverse results, circumstances or events that are subsequently discovered, could require that we cease marketing the product for that indication or expend money, time and
effort to ensure full compliance, which could have a material adverse effect on our business.

Any
failure by us, or by any third parties that may manufacture or market our products, to comply with the law, including statutes and regulations administered by the FDA or other U.S.
or foreign regulatory authorities, could result in, among other things, warning letters, fines and other civil penalties, suspension of regulatory approvals and the resulting requirement that we
suspend sales of our products, refusal to approve pending applications or supplements to approved applications, export or import restrictions, interruption of production, operating restrictions,
closure of the facilities used by us or third parties to manufacture our product candidates, injunctions or criminal prosecution. Any of the foregoing actions could have a material adverse effect on
our business.

The
healthcare community has relatively little experience with therapies based on cellular medicine and, accordingly, if our product candidates do not become widely accepted by
physicians, patients, third party payors or the healthcare community, we may be unable to generate significant revenue, if any.

We
are developing cell-based therapy product candidates for the treatment of heart damage that represent novel and unproven treatments and, if approved, will compete with a
number of more conventional products and therapies manufactured and marketed by others, including major pharmaceutical companies. We cannot predict or guarantee that physicians, patients, healthcare
insurers, third party payors or health maintenance organizations, or the healthcare community in general, will accept or utilize any of our product candidates. We anticipate that, if approved, we will
market our myoblast product primarily to interventional cardiologists, who are generally not the primary care physicians for patients who may be eligible for treatment with MyoCell. Accordingly, our

39

---



commercial
success may be dependent on third party physicians referring their patients to interventional cardiologists for MyoCell treatment.

If we are successful in obtaining regulatory approval for any of our product candidates, the degree of market acceptance of those products will depend on many
factors, including:



Failure
to achieve market acceptance would limit our ability to generate revenue and would have a material adverse effect on our business. In addition, if any of our product candidates
achieve market acceptance, we may not be able to maintain that market acceptance over time if competing products or technologies are introduced that are received more favorably or are more
cost-effective.

Risks Relating to the September 2005, September 2006, and August 2007 Financings

If we are required for any reason to repay our outstanding debentures we would be required to deplete our working capital, if available, or raise additional
funds. Our failure to repay the convertible debentures, if required, could result in legal action against us, which could require the sale of substantial
assets.We have outstanding, as of September 1, 2007, $23,479,420 aggregate original
principal amount of convertible debentures with an original issue discount of 20.3187% with $12,550,000 in 2007 Debentures, $8,259,767 in 2006 Debentures, and $2,669,653 in 2005 Debentures. We are
required to redeem on a monthly basis, by payment, at our option, with cash or with shares of our common stock, 1/30th of the aggregate original principal amount of the debentures.

The
2005 Debentures are due and payable on September 14, 2008, unless sooner converted into shares of our common stock, the 2006 Debentures are due and payable on
February 28, 2010, and the 2007 Debentures are due and payable on August 31, 2010, unless sooner converted into shares of our common stock. Any event of default could require the early
repayment of the convertible debentures, including the accruing of interest on the outstanding principal balance of the debentures if the default is not cured with the specified grace period. We
anticipate that the full amount of the convertible debentures will be converted into shares of our common stock, in accordance with the terms of the convertible debentures; however no assurance can be
provided that any amount of debentures will be converted. If, prior to the maturity date, we are required to repay the convertible debentures in full, we would be required to use our limited working
capital and raise additional funds. If we were unable to

40

---



repay
the notes when required, the debenture holders could commence legal action against us to recover the amounts due. Any such action could require us to curtail or cease operations.

There are a large number of shares underlying our convertible debentures in full, and warrants that are registered and available for sale and the sale of these
shares may depress the market price of our common stock.As of September 1, 2007, we had:



Sales
of a substantial number of shares of our common stock in the public market could adversely affect the market price for our common stock and make it more difficult for you to sell
shares of our common stock at times and prices that you feel are appropriate.

The issuance of shares upon conversion of the convertible debentures and exercise of outstanding warrants will cause immediate and substantial dilution to our
existing stockholders.The issuance of shares upon conversion of the convertible debentures and exercise of warrants, including the replacement warrants, will
result in substantial dilution to the interests of other stockholders since the selling security holders may ultimately convert and sell the full amount issuable on conversion. Although no single
selling security holder may convert its convertible debentures and/or exercise its warrants if such conversion or exercise would cause it to own more than 4.99% of our outstanding common stock, this
restriction does not prevent each selling security holder from converting and/or exercising some of its holdings and then converting the rest of its holdings. In this way, each selling security holder
could sell more than this limit while never holding more than this limit. There is no upper limit on the number of shares that may be issued which will have the effect of further diluting the
proportionate equity interest and voting power of holders of our common stock, including investors in this offering. In addition, the issuance of the 2007 Debentures and the 2007 Warrants triggered
certain anti-dilution rights for certain third parties currently holding our securities resulting in substantial dilution to the interests of other stockholders.

Payment of mandatory monthly redemptions in shares of common stock will result in substantial dilution.We expect to satisfy
all or a significant portion of our obligation to redeem 1/30th of the aggregate original principal amount of debentures per month through issuance of additional shares of our common stock. This
approach will result in substantial dilution to the interests of other stockholders. In addition, many of our outstanding securities contain anti-dilution protections that will result in
further dilution in the event the redemption prices associated with the monthly redemptions are below $.25 per share of our common stock.

41

---



If we fail to effect and maintain registration of the common stock issued or issuable pursuant to conversion of our debentures, or upon exercise of our warrants,
we may be obligated to pay the investors of those securities liquidated damages.We have various obligations to file and obtain the effectiveness of certain
registration statements which include certain outstanding common stock and common stock underlying outstanding debentures and common stock underlying the warrants. If we fail to meet any obligations
we have to have effective and current registration statements available (including the current registration statement related to the common stock underlying our debentures and warrants), we may become
obligated to pay liquidated damages to investors to the extent they may be entitled to such damages. In addition, to the filing of registration statements in connection with the 2007 Financing
pursuant to the amendments to the 2005 and 2006 financing documents described above, we are contractually obligated to file additional registration statements at various times in the future. Because
of the SEC's recent interpretation of Rule 415, we cannot offer any assurances that we will be able to obtain the effectiveness of any registration statement or post-effective
amendments that we may file.

Our
outstanding indebtedness on our 2005, 2006 and 2007 Debentures imposes certain restrictions on how we conduct our business. In addition, all of our assets, including our intellectual
property, are pledged to secure this indebtedness. If we fail to meet our obligations under the Debentures, our payment obligations may be accelerated and the collateral securing the debt may be sold
to satisfy these obligations.

The
Debentures and related agreements contain various provisions that restrict our operating flexibility. Pursuant to the agreement, we may not, among other things:



These
provisions could have important consequences for us, including (i) making it more difficult for us to obtain additional debt financing from another lender, or obtain new
debt financing on terms favorable to us, (ii) causing us to use a portion of our available cash for debt repayment and service

42

---



rather
than other perceived needs and/or (iii) impacting our ability to take advantage of significant, perceived business opportunities.

Our obligations under the Securities Purchase Agreement are secured by substantially all of our assets.Our obligations under
the security agreement, executed in connection with the 2007 Financing, with the holders of the debentures and warrants are secured by substantially all of our assets. As a result, if we default under
the terms of the security agreement, such holders could foreclose on their security interest and liquidate all of our assets. This would cause operations to cease.

Risks Relating to Government Regulation

Companies such as ours engaged in research using nuclear transfer and embryonic stem cells are currently subject to strict government regulations, and our
operations could be harmed by any legislative or administrative efforts impacting the use of nuclear transfer technology or human embryonic material.Our business
is focused on human cell therapy, which includes the production of human differentiated cells from stem cells and involves the use of nuclear transfer technology, human oocytes, and embryonic material
as well as adult stem cells. Nuclear transfer technology, commonly known as therapeutic cloning, and research utilizing embryonic stem cells are controversial subjects, and are currently subject to
intense scrutiny, both in the United States, the United Nations and throughout the world, particularly in the area of nuclear transfer of human cells and the use of human embryonic material.

We
cannot assure you that our operations will not be harmed by any legislative or administrative efforts by politicians or groups opposed to the development of nuclear transfer
technology generally or the use of nuclear transfer for therapeutic cloning of human cells specifically. Further, we cannot assure you that legislative or administrative restrictions directly or
indirectly delaying, limiting or preventing the use of nuclear transfer technology or human embryonic material or the sale, manufacture or use of products or services derived from nuclear transfer
technology or human embryonic material will not be adopted in the future.

Restrictions on the use of human embryonic stem cells, and the ethical, legal and social implications of that research, could prevent us from developing or
gaining acceptance for commercially viable products in these areas.Some of our most important programs involve the use of stem cells that are derived from human
embryos. The use of human embryonic stem cells gives rise to ethical, legal and social issues regarding the appropriate use of these cells. In the event that our research related to human embryonic
stem cells becomes the subject of adverse commentary or publicity, the market price for our common stock could be significantly harmed. Some political and religious groups have voiced opposition to
our technology and practices. We use stem cells derived from human embryos that have been created for in vitro fertilization procedures but are no longer desired or suitable for that use and are
donated with appropriate informed consent for research use. Many research institutions, including some of our scientific collaborators, have adopted policies regarding the ethical use of human
embryonic tissue. These policies may have the effect of limiting the scope of research conducted using human embryonic stem cells, thereby impairing our ability to conduct research in this field.

Potential
and actual legislation and regulation at the federal or state level related to our technology could limit our activities and ability to develop products for commercial sales,
depriving us of our anticipated source of future revenues. Legislative bills could be introduced in the future aiming to prohibit the use or commercialization of somatic cell nuclear transfer
technology or of any products resulting from it, including those related to human therapeutic cloning and regenerative medicine. Such legislation could have a significant influence on our ability to
pursue our research, development and commercialization plans in the United States.

43

---



Any
future or additional government-imposed restrictions in these or other jurisdictions with respect to use of embryos or human embryonic stem cells in research and development could
have a material adverse effect on us, by, among other things:



Because we or our collaborators must obtain regulatory approval to market our products in the United States and other countries, we cannot predict whether or when
we will be permitted to commercialize our products.Federal, state and local governments in the United States and governments in other countries have significant
regulations in place that govern many of our activities. We are or may become subject to various federal, state and local laws, regulations and recommendations relating to safe working conditions,
laboratory and manufacturing practices, the experimental use of animals and the use and disposal of hazardous or potentially hazardous substances used in connection with our research and development
work. The preclinical testing and clinical trials of the products that we or our collaborators develop are subject to extensive government regulation that may prevent us from creating commercially
viable products from our discoveries. In addition, the sale by us or our collaborators of any commercially viable product will be subject to government regulation from several standpoints, including
manufacturing, advertising and promoting, selling and marketing, labeling, and distributing.

If,
and to the extent that, we are unable to comply with these regulations, our ability to earn revenues will be materially and negatively impacted. The regulatory process, particularly
in the biotechnology field, is uncertain, can take many years and requires the expenditure of substantial resources. Biological drugs and non-biological drugs are rigorously regulated. In
particular, proposed human pharmaceutical therapeutic product candidates are subject to rigorous preclinical and clinical testing and other requirements by the FDA in the United States and similar
health authorities in other countries in order to demonstrate safety and efficacy. We may never obtain regulatory approval to market our proposed products. For additional information about
governmental regulations that will affect our planned and intended business operations, see the Company's Annual Report on Form 10-KSB filed with the SEC on March 19, 2007
under the heading "DESCRIPTION OF BUSINESSGovernment Regulation".

Our
products may not receive FDA approval, which would prevent us from commercially marketing our products and producing revenues. The FDA and comparable government agencies in foreign
countries impose substantial regulations on the manufacture and marketing of pharmaceutical products through lengthy and detailed laboratory, pre-clinical and clinical testing procedures,
sampling activities and other costly and time-consuming procedures. Satisfaction of these regulations typically takes several years or more and varies substantially based upon the type,
complexity and novelty of the proposed product. We cannot assure you that FDA approvals for any products developed by us will be granted on a timely basis, if at all. Any such delay in obtaining, or
failure to obtain, such approvals could have a material adverse effect on the marketing of our products and our ability to generate product revenue. For additional information about governmental
regulations that will affect our planned and intended business operations, see see the Company's Annual Report on Form 10-KSB filed with the SEC on March 19, 2007 under the
heading "DESCRIPTION OF BUSINESSGovernment Regulation".

For-profit entities may be prohibited from benefiting from grant funding.There has been much publicity about
grant resources for stem cell research, including Proposition 71 in California, which is described more fully under the heading "DESCRIPTION OF BUSINESSCalifornia
Proposition 71"

44

---



in
the Company's Annual Report on Form 10-KSB filed with the SEC on March 19, 2007. Rules and regulations related to any funding that may ultimately be provided, the type of
entity that will be eligible for funding, the science to be funded, and funding details have not been finalized. As a result of these uncertainties regarding Proposition 71, we cannot assure you that
funding, if any, will be available to us, or any for-profit entity.

The government maintains certain rights in technology that we develop using government grant money and we may lose the revenues from such technology if we do not
commercialize and utilize the technology pursuant to established government guidelines.Certain of our and our licensors' research has been or is being funded in
part by government grants. In connection with certain grants, the U.S. government retains rights in the technology developed with the grant. These rights could restrict our ability to fully capitalize
upon the value of this research.

Risks Relating to Our Reliance on Third Parties

We depend on our collaborators to help us develop and test our proposed products, and our ability to develop and commercialize products may be impaired or delayed
if collaborations are unsuccessful.Our strategy for the development, clinical testing and commercialization of our proposed products requires that we enter into
collaborations with corporate partners, licensors, licensees and others. We are dependent upon the subsequent success of these other parties in performing their respective responsibilities and the
continued cooperation of our partners. Our collaborators may not cooperate with us or perform their obligations under our agreements with them. We cannot control the amount and timing of our
collaborators' resources that will be devoted to our research and development activities related to our collaborative agreements with them. Our collaborators may choose to pursue existing or
alternative technologies in preference to those being developed in collaboration with us.

Under
agreements with collaborators, we may rely significantly on such collaborators to, among other things:



The
development and commercialization of potential products will be delayed if collaborators fail to conduct these activities in a timely manner or at all. In addition, our collaborators
could terminate their agreements with us and we may not receive any development or milestone payments. If we do not achieve milestones set forth in the agreements, or if our collaborators breach or
terminate their collaborative agreements with us, our business may be materially harmed.

Our reliance on the activities of our non-employee consultants, research institutions, and scientific contractors, whose activities are not wholly
within our control, may lead to delays in development of our proposed products.We rely extensively upon and have relationships with scientific consultants at
academic and other institutions, some of whom conduct research at our request, and other consultants with expertise in clinical development strategy or other matters. These consultants are not our
employees and may have commitments to, or consulting or advisory contracts with, other entities that may limit their availability to us. We have limited control over the activities of these
consultants and, except as otherwise required by our collaboration and consulting agreements to the extent they exist, can expect only limited amounts of their time to be dedicated to our activities.

In
addition, we have formed research collaborations with academic and other research institutions throughout the world. These research facilities may have commitments to other commercial
and

45

---



non-commercial
entities. We have limited control over the operations of these laboratories and can expect only limited amounts of time to be dedicated to our research goals.

We
also rely on other companies for certain process development or other technical scientific work. We have contracts with these companies that specify the work to be done and results to
be achieved, but we do not have direct control over their personnel or operations. If any of these third parties are
unable or refuse to contribute to projects on which we need their help, our ability to generate advances in our technologies and develop our products could be significantly harmed.

General Risks Relating to Our Business

We may be subject to litigation that will be costly to defend or pursue and uncertain in its outcome.Our business may bring
us into conflict with our licensees, licensors, or others with whom we have contractual or other business relationships, or with our competitors or others whose interests differ from ours. If we are
unable to resolve those conflicts on terms that are satisfactory to all parties, we may become involved in litigation brought by or against us. That litigation is likely to be expensive and may
require a significant amount of management's time and attention, at the expense of other aspects of our business. The outcome of litigation is always uncertain, and in some cases could include
judgments against us that require us to pay damages, enjoin us from certain activities, or otherwise affect our legal or contractual rights, which could have a significant adverse effect on our
business.

We may not be able to obtain third-party patient reimbursement or favorable product pricing, which would reduce our ability to operate
profitably.Our ability to successfully commercialize certain of our proposed products in the human therapeutic field may depend to a significant degree on patient
reimbursement of the costs of such products and related treatments at acceptable levels from government authorities, private health insurers and other organizations, such as health maintenance
organizations. We cannot assure you that reimbursement in the United States or foreign countries will be available for any products we may develop or, if available, will not be decreased in the
future, or that reimbursement amounts will not reduce the demand for, or the price of, our products with a consequent harm to our business. We cannot predict what additional regulation or legislation
relating to the health care industry or third-party coverage and reimbursement may be enacted in the future or what effect such regulation or legislation may have on our business. If additional
regulations are overly onerous or expensive, or if health care related legislation makes our business more expensive or burdensome than originally anticipated, we may be forced to significantly
downsize our business plans or completely abandon our business model.

Our products are likely to be expensive to manufacture, and they may not be profitable if we are unable to control the costs to manufacture
them.Our products are likely to be significantly more expensive to manufacture than most other drugs currently on the market today. Our present manufacturing
processes produce modest quantities of product intended for use in our ongoing research activities, and we have not developed processes, procedures and capability to produce commercial volumes of
product. We hope to substantially reduce manufacturing costs through process improvements, development of new science, increases in manufacturing scale and outsourcing to experienced manufacturers. If
we are not able to make these or other improvements, and depending on the pricing of the product, our profit margins may be significantly less than that of most drugs on the market today. In addition,
we may not be able to charge a high enough price for any cell therapy product we develop, even if they are safe and effective, to make a profit. If we are unable to realize significant profits from
our potential product candidates, our business would be materially harmed.

46

---





To be successful, our proposed products must be accepted by the health care community, which can be very slow to adopt or unreceptive to new technologies and
products.Our proposed products and those developed by our collaborative partners, if approved for marketing, may not achieve market acceptance since hospitals,
physicians, patients or the medical community in general may decide not to accept and utilize these products. The products that we are attempting to develop represent substantial departures from
established treatment methods and will compete with a number of more conventional drugs and therapies manufactured and marketed by major pharmaceutical companies. The degree of market acceptance of
any of our developed products will depend on a number of factors, including:



If
the health care community does not accept our products for any of the foregoing reasons, or for any other reason, our business would be materially harmed.

Our current source of revenues depends on the stability and performance of our sublicensees.Our ability to collect royalties
on product sales from our sublicensees will depend on the financial and operational success of the companies operating under a sublicense. Revenues from those licensees will depend upon the financial
and operational success of those third parties. We cannot assure you that these licensees will be successful in obtaining requisite financing or in developing and successfully marketing their
products. These licensees may experience unanticipated obstacles including regulatory
hurdles, and scientific or technical challenges, which could have the effect of reducing their ability to generate revenues and pay us royalties.

We depend on key personnel for our continued operations and future success, and a loss of certain key personnel could significantly hinder our ability to move
forward with our business plan.Because of the specialized nature of our business, we are highly dependent on our ability to identify, hire, train and retain
highly qualified scientific and technical personnel for the research and development activities we conduct or sponsor. The loss of one or more certain key executive officers, or scientific officers,
would be significantly detrimental to us. In addition, recruiting and retaining qualified scientific personnel to perform research and development work is critical to our success. Our anticipated
growth and expansion into areas and activities requiring additional expertise, such as clinical testing, regulatory compliance, manufacturing and marketing, will require the addition of new management
personnel and the development of additional expertise by existing management personnel. There is intense competition for qualified personnel in the areas of our present and planned activities, and
there can be no assurance that we will be able to continue to attract and retain the qualified personnel necessary for the development of our business. The failure to attract and retain such personnel
or to develop such expertise would adversely affect our business.

Our credibility as a business operating in the field of human embryonic stem cells is largely dependent upon the support of our Ethics Advisory
Board.Because the use of human embryonic stem cells gives rise to ethical, legal and social issues, we have instituted an Ethics Advisory Board. Our Ethics
Advisory Board is made up of highly qualified individuals with expertise in the field of human embryonic stem cells. We cannot assure you that these members will continue to serve on our Ethics
Advisory Board, and the loss of any such member may affect the credibility and effectiveness of the Board. As a result, our business may be materially harmed in the event of any such loss.

47

---



Our insurance policies may be inadequate and potentially expose us to unrecoverable risks.We have limited director and
officer insurance and commercial insurance policies. Any significant insurance claims would have a material adverse effect on our business, financial condition and results of operations. Insurance
availability, coverage terms and pricing continue to vary with market conditions. We endeavor to obtain appropriate insurance coverage for insurable risks that we identify, however, we may fail to
correctly anticipate or quantify insurable risks, we may not be able to obtain appropriate insurance coverage, and insurers may not respond as we intend to cover insurable events that may occur. We
have observed rapidly changing conditions in the insurance markets relating to nearly all areas of traditional corporate insurance. Such conditions have resulted in higher premium costs, higher policy
deductibles, and lower coverage limits. For some risks, we may not have or maintain insurance coverage because of cost or availability.

We have no product liability insurance, which may leave us vulnerable to future claims we will be unable to satisfy.The
testing, manufacturing, marketing and sale of human therapeutic products entail an inherent risk of product liability claims, and we cannot assure you that substantial product liability
claims will not be asserted against us. We have no product liability insurance. In the event we are forced to expend significant funds on defending product liability actions, and in the event those
funds come from operating capital, we will be required to reduce our business activities, which could lead to significant losses.

We
cannot assure you that adequate insurance coverage will be available in the future on acceptable terms, if at all, or that, if available, we will be able to maintain any such
insurance at sufficient levels of coverage or that any such insurance will provide adequate protection against potential liabilities. Whether or not a product liability insurance policy is obtained or
maintained in the future, any product liability claim could harm our business or financial condition.

We presently have members of management and other key employees located in various locations throughout the country which adds complexities to the operation of
the business.Presently, we have members of management and other key employees located in both California and Massachusetts, which adds complexities to the
operation of our business. We intend to maintain our research facilities in Massachusetts and we have established corporate offices and an additional research facility in California. We will likely
continue to incur significant costs associated with maintaining multiple locations.

We face risks related to compliance with corporate governance laws and financial reporting standards.The Sarbanes-Oxley Act
of 2002, as well as related new rules and regulations implemented by the Securities and Exchange Commission and the Public Company Accounting Oversight Board, require changes in the corporate
governance practices and financial reporting standards for public companies. These new laws, rules and regulations, including compliance with Section 404 of the Sarbanes-Oxley Act of 2002
relating to internal control over financial reporting, referred to as Section 404, have materially increased our legal and financial compliance costs and made some activities more
time-consuming and more burdensome. Section 404 requires that by 2007 our management assess our internal control over financial reporting annually and include a report on its
assessment in our annual report. In 2008 our independent registered public accounting firm may be required to audit both the design and operating effectiveness of our internal controls and
management's assessment of the design and the operating effectiveness of our internal control over financial reporting.

Risks Relating to Our Common Stock

Stock prices for biotechnology companies have historically tended to be very volatile.Stock prices and trading volumes for
many biotechnology companies fluctuate widely for a number of reasons,

48

---



including
but not limited to the following factors, some of which may be unrelated to their businesses or results of operations:



This
market volatility, as well as general domestic or international economic, market and political conditions, could materially and adversely affect the market price of our common stock
and the return on your investment.

A significant number of shares of our common stock have become available for sale and their sale could depress the price of our common
stock.On September 15, 2007, a significant number of our outstanding securities (including the 2005 Debentures, the 2005 Warrants and the shares of common
stock underlying such securities) that were previously restricted became eligible for sale under Rule 144(k) of the Securities Act, and their sale will not be subject to any volume limitations.

Not
including the shares of common stock underlying the 2005 Debentures, the 2005 Warrants, the 2006 Debentures, the 2006 Warrants, the replacement warrants, the 2007 Debentures, and the
2007 Warrants, there are presently approximately 92,169,478 outstanding options, warrants and other securities convertible or exercisable into shares of our common stock.

We
may also sell a substantial number of additional shares of our common stock in connection with a private placement or public offering of shares of our common stock (or other series or
class of capital stock to be designated in the future). The terms of any such private placement would likely require us to register the resale of any shares of capital stock issued or issuable in the
transaction. We have also issued common stock to certain parties, such as vendors and service providers, as payment for products and services. Under these arrangements, we may agree to register the
shares for resale soon after their issuance. We may also continue to pay for certain goods and services with equity, which would dilute your interest in the company.

Sales
of a substantial number of shares of our common stock under any of the circumstances described above could adversely affect the market price for our common stock and make it more
difficult for you to sell shares of our common stock at times and prices that you feel are appropriate.

We do not intend to pay cash dividends on our common stock in the foreseeable future.Any payment of cash dividends will
depend upon our financial condition, results of operations, capital requirements and other factors and will be at the discretion of our board of directors. We do not anticipate paying cash dividends
on our common stock in the foreseeable future. Furthermore, we may incur additional indebtedness that may severely restrict or prohibit the payment of dividends.

49

---



Our securities are quoted on the OTC Bulletin Board, which may limit the liquidity and price of our securities more than if our securities were quoted or listed
on the Nasdaq Stock Market or a national exchange.Our securities are currently quoted on the OTC Bulletin Board, an NASD-sponsored and operated
inter-dealer automated quotation system for equity securities not included in the Nasdaq Stock Market. Quotation of our securities on the OTC Bulletin Board may limit the liquidity and price of our
securities more than if our securities were quoted or listed on The Nasdaq Stock Market or a national exchange. Some investors may perceive our securities to be less attractive because they are traded
in the over-the-counter market. In addition, as an OTC Bulletin Board listed company, we do not attract the extensive analyst coverage that accompanies companies listed on
Nasdaq or any other regional or national exchange. Further, institutional and other investors may have investment guidelines that restrict or prohibit investing in securities traded in the
over-the-counter market. These factors may have an adverse impact on the trading and price of our securities.

Our common stock is subject to "penny stock" regulations and restrictions on initial and secondary broker-dealer sales.The
Securities and Exchange Commission has adopted regulations which generally define "penny stock" to be any listed, trading equity security that has a market price less than $5.00 per share or an
exercise price of less than $5.00 per share, subject to certain exemptions. Penny stocks are subject to certain additional oversight and regulatory requirements. Brokers and dealers affecting
transactions in our common stock in many circumstances must obtain the written consent of a customer prior to purchasing our common stock, must obtain information from the customer and must provide
disclosures to the customer. These requirements may restrict the ability of broker-dealers to sell our common stock and may affect your ability to sell your shares of our common stock in the secondary
market.

ITEM 3.    CONTROLS AND PROCEDURES



At
the end of 2007, Section 404 of the Sarbanes-Oxley Act will require our management to provide an assessment of the effectiveness of our internal control over financial
reporting, and at the end of 2008, our independent registered public accountants will be required to audit management's assessment. We are in the process of performing the system and process
documentation, evaluation and testing required for management to make this assessment and for its independent registered public accountants to provide their attestation report. We have not completed
this process or its assessment, and this process will require significant amounts of management time and resources. In the course of evaluation and testing, management may identify deficiencies that
will need to be addressed and remediated.

50

---



PART II. OTHER INFORMATION

ITEM 1.    LEGAL PROCEEDINGS

None.

ITEM 2.    UNREGISTERED SALES OF EQUITY SECURITIES AND USE OF PROCEEDS

The issuances of the equity securities described below were made in reliance upon the exemption from registration under Section 4(2) of the Securities Act
of 1933, as amended, relating to sales by an issuer not involving a public offering, and/or pursuant to the requirements of one or more of the safe harbors provided in Regulation D under the
Securities Act or, in the case of equity compensation to employees, directors and eligible consultants, Rule 701 therewith.

In
connection with our merger with Mytogen, Inc. which closed on September 20, 2007, we issued the following securities to the former stockholders of Mytogen in exchange
for all of their shares of that company: (i) 8,064,517 shares of our common stock having an aggregate value of $5,000,000 based on a per share price of $0.62, and/or (ii) warrants to
purchase an aggregate of 1,500,000 shares of our common stock at an exercise price of $0.75 per share. Of the 8,064,517 shares of our common stock issued in connection with the closing, fifteen
percent (15%) or 1,209,675, of such shares were issued to Mellon Trust of New England, N.A., as escrow agent, and will be held in escrow for a period of eighteen (18) months in accordance with
the terms of the escrow agreement executed in connection with the closing of the transaction.

On
September 20, 2007, we issued to GenVec, Inc. a warrant to purchase an aggregate of 150,000 shares of common stock of the Company to at an exercise price of $0.75.

On
August 31, 2007, as described in our Current Report on Form 8-K filed with the Securities and Exchange Commission on September 7, 2006, we issued to
certain accredited investors an aggregate of $12,550,000 principal amount senior secured convertible debentures with an original issue discount of 20.3187%. In connection with the closing of the
issuance and sale of convertible
debentures, we received gross proceeds of $10,000,000. The convertible debentures are due and payable three years from the date of issuance, unless sooner converted into shares of our common stock.
The conversion price of the debentures is $0.34, subject to anti-dilution and other customary adjustments. In connection with the securities purchase agreement, we also issued warrants to
purchase an aggregate of 36,911,765 shares of our common stock. The term of the warrants is five years and the exercise price is $0.38 per share, subject to anti-dilution and other
customary adjustments.

On
September 7, 2007, in connection with the closing of the 2007 financing described in our Current Report on Form 8-K filed with the Securities and Exchange
Commission on September 7, 2007, we issued warrants to purchase an aggregate of 6,328,890 shares of common stock of the Company at an exercise price of $0.38 to the following placement agents:
T.R. Winston & Company, LLC, Burrill Merchant Advisors Group, LLC, Rodman & Renshaw, Perrin Holding & Davenport Capital Corp.

On
August 14, 2007, in connection with an interim bridge financing arrangement as described in our Current Report on Form 8-K filed with the Securities and
Exchange Commission on August 20, 2006, we issued a convertible promissory note to PDP I, LLC, a Delaware limited liability company, in the principal amount of up to $600,000. The note provided
for an interest rate of 9%. The entire principal and interest on the note was either (1) due and payable on September 30, 2007 or (ii) convertible at the Company's discretion into
the securities issued in connection with the consummation of the Company's next equity or debt financing. The entire principal amount of the note was converted in connection into convertible
debentures and warrants in connection with the 2007 debenture and warrant financing described above.

51

---



On
July 1, 2007, we issued a warrant to purchase 650,000 shares of common stock at an exercise price of $0.38 per share to William Woodward in connection with consulting services
provided to us.

ITEM 3.    DEFAULTS UPON SENIOR SECURITIES

None.

ITEM 4.    SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS

None.

ITEM 5.    OTHER INFORMATION

None.

52

---



ITEM 6.    EXHIBITS

|Exhibit No. |  | Exhibit Description                                                                                                                                                                                                                                                                                                                                                      
|----------- |  | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
|10.1        |  | Agreement and Plan of Merger by and among Advanced Cell Technology, Inc., ACT Acquisition Sub, Inc., Mytogen, Inc. and certain shareholders of Mytogen, Inc., dated as of July 31, 2007 (previously filed as Exhibit 10.101 to the Registrant's
Registration Statement on Form SB-2 filed on October 1, 2007 (File No. 000-50295) and incorporated by reference herein). 
|10.2        |  | Escrow Agreement by and among Advanced Cell Technology, Inc. and certain former shareholders of Mytogen, Inc., dated as of September 20, 2007 (previously filed as Exhibit 10.102 to the Registrant's Registration Statement on Form SB-2 filed on October
1, 2007 (File No. 000-50295) and incorporated by reference herein).                                           
|10.3        |  | Securities Purchase Agreement dated August 31, 2007 (previously filed as Exhibit 10.1 to the Registrant's Current Report on Form 8-K filed on September 7, 2007 (File No. 000-50295) and incorporated by reference herein).                                                                                                                                              
|10.4        |  | Registration Rights Agreement dated August 31, 2007 (previously filed as Exhibit 10.2 to the Registrant's Current Report on Form 8-K filed on September 7, 2007 (File No. 000-50295) and incorporated by reference herein).                                                                                                                                              
|10.5        |  | Form of Common Stock Purchase Warrant (previously filed as Exhibit 10.3 to the Registrant's Current Report on Form 8-K filed on September 7, 2007 (File No. 000-50295) and incorporated by reference herein).                                                                                                                                                            
|10.6        |  | Form of Amortizing Convertible Debenture (previously filed as Exhibit 10.4 to the Registrant's Current Report on Form 8-K filed on September 7, 2007 (File No. 000-50295) and incorporated by reference herein).                                                                                                                                                         
|10.7        |  | Form of Security Agreement dated August 31, 2007 (previously filed as Exhibit 10.5 to the Registrant's Current Report on Form 8-K filed on September 7, 2007 (File No. 000-50295) and incorporated by reference herein).                                                                                                                                                 
|10.8        |  | Form of Subsidiary Guaranty dated August 31, 2007 (previously filed as Exhibit 10.6 to the Registrant's Current Report on Form 8-K filed on September 7, 2007 (File No. 000-50295) and incorporated by reference herein).                                                                                                                                                
|10.9        |  | Form of Lock-up Agreement (previously filed as Exhibit 10.7 to the Registrant's Current Report on Form 8-K filed on September 7, 2007 (File No. 000-50295) and incorporated by reference herein).                                                                                                                                                                        
|10.10       |  | Amended and Restated Consulting Agreement, dated as of September 19, 2007 by and between Advanced Cell Technology, Inc., through its wholly owned subsidiary Mytogen, Inc., and Dib, LLC (previously filed as Exhibit 10.110 to the Registrant's
Registration Statement on Form SB-2 filed on October 1, 2007 (File No. 000-50295) and incorporated by reference herein).
|10.11       |  | Employment Agreement, dated as of September 20, 2007, by and between Advanced Cell Technology, Inc., and Jonathan Dinsmore (previously filed as Exhibit 10.111 to the Registrant's Registration Statement on Form SB-2 filed on
October 1, 2007 (File No. 000-50295) and incorporated by reference herein).                                                              
|            |  |                                                                                                                                                                                                                                                                                                                                                                          

53

---



|10.12 |  | Nomination Agreement, dated September 20, 2007, by and between Advanced Cell Technology, Inc. and Anthem Ventures Fund, L.P. (previously filed as Exhibit 10.112 to the Registrant's Registration Statement on Form SB-2 filed on October 1,
2007 (File No. 000-50295) and incorporated by reference herein).                                            
|----- |  | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
|10.13 |  | Patent Assignment and Security Agreement by and between Mytogen, Inc. and GenVec Inc. dated as of December 28, 2005, as amended pursuant to that certain Addendum to Patent Assignment and Security Agreement by and between Mytogen, Inc.
and GenVec Inc. dated as of July 31, 2007.*                                                                   
|10.14 |  | Patent License Agreement by and between Diacrin, Inc. and Cardion Pharmaceuticals, Inc. dated as of September 30, 2002, and subsequently assigned to Mytogen, Inc. on December 28, 2005.*                                                                                                                                                                
|10.15 |  | Lease Agreement by and between Mytogen, Inc. and ARE-79/96 Charlestown Navy Yard, LLC dated as of November 7, 2006, as amended pursuant to that certain Assignment and Assumption of, and First Amendment to, Lease by and among Advanced Cell
Technology, Inc., Mytogen, Inc., and ARE-79/96 Charlestown Navy Yard, LLC dated as of September 20, 2007.*
|10.16 |  | Consulting Agreement, dated as of September 14, 2007 by and between Advanced Cell Technology, Inc. and Robert Peabody.*                                                                                                                                                                                                                                  
|10.17 |  | Convertible Promissory Note issued by Advanced Cell Technology, Inc. in favor of PDP I, LLC, dated as of August 14, 2007.*                                                                                                                                                                                                                               
|31.1  |  | Section 302 Certification of Chief Executive Officer*                                                                                                                                                                                                                                                                                                    
|31.2  |  | Section 302 Certification of Chief Accounting Officer*                                                                                                                                                                                                                                                                                                   
|32.1  |  | Certification of Chief Executive Officer pursuant to 18 U.S.C. Section 1350*                                                                                                                                                                                                                                                                             
|32.2  |  | Certification of Chief Accounting Officer pursuant to 18 U.S.C. Section 1350*                                                                                                                                                                                                                                                                            
|99.1  |  | Press Release dated September 4, 2007 (previously filed as Exhibit 99.1 to the Registrant's Current Report on Form 8-K filed on September 7, 2007 (File No. 000-50295) and incorporated by reference herein).                                                                                                                                            

---

54

---





SIGNATURE

Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned
hereunto duly authorized.

|                         |  | ADVANCED CELL TECHNOLOGY, INC.
|------------------------ |  | ------------------------------
|                         |  | By:                           
|Dated: November 14, 2007 |  |                               

55

---





Exhibit Index

|Exhibit No. |  | Exhibit Description                                                                                                                                                                                                                                                                                                                                                      
|----------- |  | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
|10.1        |  | Agreement and Plan of Merger by and among Advanced Cell Technology, Inc., ACT Acquisition Sub, Inc., Mytogen, Inc. and certain shareholders of Mytogen, Inc., dated as of July 31, 2007 (previously filed as Exhibit 10.101 to the Registrant's
Registration Statement on Form SB-2 filed on October 1, 2007 (File No. 000-50295) and incorporated by reference herein). 
|10.2        |  | Escrow Agreement by and among Advanced Cell Technology, Inc. and certain former shareholders of Mytogen, Inc., dated as of September 20, 2007 (previously filed as Exhibit 10.102 to the Registrant's Registration Statement on Form SB-2
filed on October 1, 2007 (File No. 000-50295) and incorporated by reference herein).                                           
|10.3        |  | Securities Purchase Agreement dated August 31, 2007 (previously filed as Exhibit 10.1 to the Registrant's Current Report on Form 8-K filed on September 7, 2007 (File No. 000-50295) and incorporated by reference herein).                                                                                                                                              
|10.4        |  | Registration Rights Agreement dated August 31, 2007 (previously filed as Exhibit 10.2 to the Registrant's Current Report on Form 8-K filed on September 7, 2007 (File No. 000-50295) and incorporated by reference herein).                                                                                                                                              
|10.5        |  | Form of Common Stock Purchase Warrant (previously filed as Exhibit 10.3 to the Registrant's Current Report on Form 8-K filed on September 7, 2007 (File No. 000-50295) and incorporated by reference herein).                                                                                                                                                            
|10.6        |  | Form of Amortizing Convertible Debenture (previously filed as Exhibit 10.4 to the Registrant's Current Report on Form 8-K filed on September 7, 2007 (File No. 000-50295) and incorporated by reference herein).                                                                                                                                                         
|10.7        |  | Form of Security Agreement dated August 31, 2007 (previously filed as Exhibit 10.5 to the Registrant's Current Report on Form 8-K filed on September 7, 2007 (File No. 000-50295) and incorporated by reference herein).                                                                                                                                                 
|10.8        |  | Form of Subsidiary Guaranty dated August 31, 2007 (previously filed as Exhibit 10.6 to the Registrant's Current Report on Form 8-K filed on September 7, 2007 (File No. 000-50295) and incorporated by reference herein).                                                                                                                                                
|10.9        |  | Form of Lock-up Agreement (previously filed as Exhibit 10.7 to the Registrant's Current Report on Form 8-K filed on September 7, 2007 (File No. 000-50295) and incorporated by reference herein).                                                                                                                                                                        
|10.10       |  | Amended and Restated Consulting Agreement, dated as of September 19, 2007 by and between Advanced Cell Technology, Inc., through its wholly owned subsidiary Mytogen, Inc., and Dib, LLC (previously filed as Exhibit 10.110 to the Registrant's
Registration Statement on Form SB-2 filed on October 1, 2007 (File No. 000-50295) and incorporated by reference herein).
|10.11       |  | Employment Agreement, dated as of September 20, 2007, by and between Advanced Cell Technology, Inc., and Jonathan Dinsmore (previously filed as Exhibit 10.111 to the Registrant's Registration Statement on Form SB-2 filed on October 1, 2007 (File No.
000-50295) and incorporated by reference herein).                                                              
|            |  |                                                                                                                                                                                                                                                                                                                                                                          

56

---



|10.12 |  | Nomination Agreement, dated September 20, 2007, by and between Advanced Cell Technology, Inc. and Anthem Ventures Fund, L.P. (previously filed as Exhibit 10.112 to the Registrant's Registration Statement on Form SB-2 filed on October 1, 2007 (File
No. 000-50295) and incorporated by reference herein).                                            
|----- |  | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
|10.13 |  | Patent Assignment and Security Agreement by and between Mytogen, Inc. and GenVec Inc. dated as of December 28, 2005, as amended pursuant to that certain Addendum to Patent Assignment and Security Agreement by and between Mytogen, Inc.
and GenVec Inc. dated as of July 31, 2007.*                                                                   
|10.14 |  | Patent License Agreement by and between Diacrin, Inc. and Cardion Pharmaceuticals, Inc. dated as of September 30, 2002, and subsequently assigned to Mytogen, Inc. on December 28, 2005.*                                                                                                                                                                
|10.15 |  | Lease Agreement by and between Mytogen, Inc. and ARE-79/96 Charlestown Navy Yard, LLC dated as of November 7, 2006, as amended pursuant to that certain Assignment and Assumption of, and First Amendment to, Lease by and among Advanced Cell
Technology, Inc., Mytogen, Inc., and ARE-79/96 Charlestown Navy Yard, LLC dated as of September 20, 2007.*
|10.16 |  | Consulting Agreement, dated as of September 14, 2007 by and between Advanced Cell Technology, Inc. and Robert Peabody.*                                                                                                                                                                                                                                  
|10.17 |  | Convertible Promissory Note issued by Advanced Cell Technology, Inc. in favor of PDP I, LLC, dated as of August 14, 2007.*                                                                                                                                                                                                                               
|31.1  |  | Section 302 Certification of Chief Executive Officer*                                                                                                                                                                                                                                                                                                    
|31.2  |  | Section 302 Certification of Chief Accounting Officer*                                                                                                                                                                                                                                                                                                   
|32.1  |  | Certification of Chief Executive Officer pursuant to 18 U.S.C. Section 1350*                                                                                                                                                                                                                                                                             
|32.2  |  | Certification of Chief Accounting Officer pursuant to 18 U.S.C. Section 1350*                                                                                                                                                                                                                                                                            
|99.1  |  | Press Release dated September 4, 2007 (previously filed as Exhibit 99.1 to the Registrant's Current Report on Form 8-K filed on September 7, 2007 (File No. 000-50295) and incorporated by reference herein).                                                                                                                                            

---

57

---



QuickLinks