Acetamiprid Dietary Exposure Assessment DP No.: 372890

PC Code: 099050

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UNITED STATES ENVIRONMENTAL PROTECTION AGENCY

WASHINGTON, D.C. 20460

OFFICE OF 

PREVENTION, PESTICIDES

AND TOXIC SUBSTANCES 

MEMORANDUM

DATE: Jan 14, 2010

SUBJECT: Acetamiprid. Revised Acute and Chronic Dietary Exposure Assessments (Food 

and Drinking Water) to Support Section 3 Registration of Uses on Clover, Small 

Vine Climbing Fruits, except Fuzzy Kiwifruit, Subgroup 13-07F, Greenhouse

Grown Tomatoes and Tea.

PC Code: 099050 DP Barcode: D372890

Decision No.: 408298 Registration Nos.: 8033-23, 8033-36, 8033-94

Petition No.: 9E7544 Regulatory Action: Amended Section 3

Risk Assessment Type: Single Chemical 

Aggregate, Dietary

Case No.: N/A

TXR No.: N/A CAS No.: 135410-20-7

MRID Nos.: N/A 40 CFR: §180.578

REVIEWER: Dennis McNeilly, Chemist

Registration Action Branch 2

Health Effects Division (7509P)

THROUGH: Julie Van Alstine, MPH, Environmental Health Scientist

Douglas Dotson, Ph.D., Chemist

Dietary Exposure Science Advisory Council (DESAC)

Health Effects Division (7509P)

TO: Laura Nollen, Risk Manager Reviewer

Barbara Madden, Team Leader (RM Team 5)

RIMUERB/Registration Division (RD) (7505P)

Executive Summary

Acute and chronic dietary (food + drinking water) risk assessments were conducted using the 

Dietary Exposure Evaluation Model (DEEM-FCIDTM, Version 2.03) which uses food 
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consumption data from the USDA’s Continuing Surveys of Food Intakes by Individuals (CSFII, 

1994-1996 and 1998). Analyses were previously performed to support the requested Section 3 

registration of acetamiprid on clover, small vine climbing fruits, except kiwifruit, subgroup 13-

07F (amending grape use); green house grown tomatoes; and tea (D369019, D. McNeilly, 

12/1/2009). RD has requested that HED redo the analyses using 100% percent crop treated for 

all amended commodities, i.e., grapes and other subgroup 13-07F commodities, and tomatoes.

Acute Dietary (Food and Drinking Water) Exposure Results and Characterization

The probabilistic acute dietary exposure assessment included tolerance level residues, anticipated 

residues from field residue trials, processing factors, maximum percent crop treated (%CT)

estimates (for existing uses only) generated by the Biological and Economic Analysis Division 

(BEAD), and the modeled peak concentration of acetamiprid residues in surface and 

groundwater water sources of drinking water. Although the acute assessment has been refined, 

the resulting exposure estimates are still considered to be conservative since field trial data were 

the basis for the anticipated residues, and because a conservative drinking water model (FIRST) 

was used to estimate residues in drinking water.

Acute dietary exposure estimates at the 99.9th percentile are below HED’s level of concern for 

the general US population and all other population subgroups. For the US population, the 

estimated exposure of 0.024 mg/kg/day corresponds to 24% aPAD; for children 1-2 years old, 

the estimated exposure of 0.043 mg/kg/day corresponds to an acute dietary risk of 43% aPAD.

Chronic Dietary (Food and Drinking Water) Exposure Results and Characterization

For the chronic analysis, tolerance-level residues were assumed for all food commodities with 

existing and proposed acetamiprid tolerances. Percent crop treated was used for many 

commodities as detailed in Table 3. The chronic analysis also included the modeled surface 

water annual average residue in drinking water. Even though %CT information was used in the 

chronic analysis, the exposure and risk estimates are still conservative since tolerance level 

residues were used, because 100 %CT was assumed for crops where percent crop treated 

information was not available, and because a conservative drinking water model (FIRST) was 

used.

Chronic dietary exposure to acetamiprid, including existing and proposed uses, is below HED’s 

level of concern for the US population and all other population subgroups. For the general US 

population, an estimated exposure of 0.0028 mg/kg/day corresponds to 4% of the chronic 

population adjusted dose (cPAD); children 1-2 years old was the highest exposed population 

subgroup, with an estimate of 0.010 mg/kg/day, or 15% cPAD. Risks for all population 

subgroups are less than 100% cPAD, and are not of concern.

I. Introduction

Dietary risk assessment incorporates both exposure and toxicity of a given pesticide. For acute 
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and chronic assessments, the risk is expressed as a percentage of a maximum acceptable dose 

(i.e., the dose which HED has concluded will result in no unreasonable adverse health effects). 

This dose is referred to as the population adjusted dose (PAD). The PAD is equivalent to a point 

of departure (POD, NOAEL, LOAEL, e.g.) divided by the required uncertainty or safety factors.

For acute and non-cancer chronic exposures, HED is concerned when estimated dietary risk 

exceeds 100% of the PAD. References which discuss the acute and chronic risk assessments in 

more detail are available on the EPA/pesticides web site: “Available Information on Assessing 

Exposure from Pesticides, A User’s Guide,” 6/21/2000, web link: 

http://www.epa.gov/fedrgstr/EPA-PEST/2000/July/Day-12/6061.pdf ; or see SOP 99.6 (8/20/99).

The most recent dietary risk assessment for acetamiprid was conducted by D. McNeilly

(D369019, 12/1/09) which included proposed uses on clover, small vine climbing fruits, except 

kiwifruit, subgroup 13-07F (amending grape use); green house grown tomatoes; and tea. RD has 

requested that HED redo the analyses using 100% percent crop treated for all amended 

commodities, i.e., grapes and other subgroup 13-07F commodities, and tomatoes.

II. Residue Information

Tolerances are established for residues of the insecticide acetamiprid [40 CFR §180.578(a)], N1-

[(6-chloro-3-pyridyl)methyl]-N2-cyano-N1- methylacetamidine, in or on numerous agricultural 

commodities ranging from 0.01 ppm on mustard and canola seed to 20 ppm in or on cotton, gin 

byproducts. Tolerances are established for the combined residues of the insecticide acetamiprid, 

N1-[(6-chloro-3-pyridyl)methyl]-N2-cyano-N1- methylacetamidine, and its metabolite N1-[(6-

chloro-3-pyridyl)methyl]-N2-cyano- acetamidine [40 CFR §180.578(b)] in or on fat and meat of 

cattle, goat, hog, horse and sheep, 0.1 ppm; meat by-products of cattle, goat, hog horse and 

sheep, 0.2 ppm; milk, 0.1 ppm; poultry meat and fat, 0.01 ppm; poultry liver, 0.05 ppm; and egg, 

0.01 ppm.

The current acute and chronic dietary exposure assessments include existing uses and the 

tolerances proposed by the Interregional Research Project Number 4 (IR-4). IR-4 has submitted 

amended Section 3 registration requests for new uses of acetamiprid on clover grown for seed, 

small vine climbing fruits, except kiwifruit, subgroup 13-07F (amending established grape uses),

greenhouse-grown tomatoes, and tea.

Table 1. Recommended Tolerances

Crop Group or Commodity Recommended Tol. (ppm)

Clover, forage* 0.10*

* Tolerances with regional restrictions [i.e., 40 CFR §180.578(c)].

Clover, hay* 0.10*

* Tolerances with regional restrictions [i.e., 40 CFR §180.578(c)].

Fruit, small, vine climbing, subgroup 13-07F, 

except fuzzy kiwifruit 

0.35
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Table 1. Recommended Tolerances

Crop Group or Commodity Recommended Tol. (ppm)

Tea 50.0

Tomatoes (greenhouse grown) Note: No change is needed to the current tolerance in fruiting vegetables 

(Crop Group 8) at 0.2 ppm.

Acute Dietary Exposure Assessment

The acute dietary assessment was conducted using anticipated residues from field trials [apples; 

broccoli; cabbage, celery; grapefruit; grapes; lettuce; oranges; pears; peppers; spinach; tomatoes; 

stone fruit (crop group 12); and cucurbits (crop group 9)]. For each of the above-listed 

commodities, the individual field trial residue values (from trials reflecting the 1X application rate 

and labeled PHI, or shorter) were incorporated into a residue distribution file (RDF) for the 

probabilistic acute dietary exposure assessment. For field trial residues below the limit of 

quantification (LOQ) of 0.01 ppm, a residue value of 1⁄2 LOQ, or 0.005 ppm was assumed. For 

cabbage and head lettuce, residues in the RDF were for the raw agricultural commodity (RAC)

without wrapper leaves. For commodities with %CT data available, the RDF includes an 

indication of the number of zeroes assumed for the percent of the commodity not treated. 

Tolerance level or HED-recommended tolerance level residues were used for tree nuts, nectarines, 

collards, cauliflower, legumes, berries, bulb vegetables and for livestock commodities. For tea, 

the HED-recommended tolerance of 50 ppm was used.

A summary of the RDFs is included in Attachment 1. The orange RDF was translated to 

grapefruit, using the higher percent crop treated estimate of 5% for oranges (grapefruit was 

<2.5%). The plum RDF was translated to apricots and assumes 100% CT. These translations are 

appropriate since the field trials were conducted on the representative crops, and cover potential 

residues in the related crops, and since either no adjustment for %CT was made (plums and 

apricots) or a conservative estimate of %CT was made in these RDFs. 100% crop treated was 

assumed for grapes and tomatoes because the use patterns are being amended for these 

commodities and projected crop treated estimates are not available.

Chronic Dietary Exposure Assessment

For the chronic dietary exposure assessment, current and recommended tolerance-level residues 

were used, for all RACs and livestock commodities. Percent crop treated estimates were used for 

apple (20%), broccoli (5%), cabbage (5%), cauliflower (10%), celery (25%), cotton (5%), 

grapefruit (2.5%), lemon (5%), lettuce (10%), orange (2.5%), peach (1%), pear (35%), pepper 

(2.5%), potato (2.5%), pumpkin (1%), spinach (5%), and squash (2.5%). 100% crop treated was 

assumed for grapes and tomatoes because the use patterns are being amended for these 

commodities and projected crop treated estimates are not available.
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Processing Factors

The acute dietary exposure assessment was refined with processing factors for apple juice, orange 

juice, grapefruit juice, raisins, dried prunes, tomato paste and tomato puree. The processing 

factors were reviewed in conjunction with residue data used to determine if separate tolerances 

were needed for processed commodities. For all other commodities, the DEEMTM Version 7.81

default processing factors were used. Processing factors from study data were incorporated into 

the acute dietary assessment as follows (Table 2):

Table 2. Summary of Processing Studies Conducted with Acetamiprid.

RAC Processed Commodity Processing Factor Comments

Apple Juice 0.88 Also used for pear juice

Citrus Juice <0.16 0.16X used for both orange and grapefruit juice

Grape Juice 1 Study data showed RAC tolerance would cover 

residues in juice.

Raisins 0.9 0.9X used in assessment

Tomato Puree 1.4 1.4X used for puree in assessment

Paste 3.0 3.0X used for paste in acute assessment.

Plum Prune, dried 2.9X 2.0X used for dried prunes used in acute assessment. 

The drying factor was translated to dried apricots and 

dried peaches in the acute dietary assessment.

For the chronic dietary exposure assessment, the DEEMTM Version 7.81 default processing 

factors were used for all commodities for which they are available, with the exception of grape 

juice, and raisins (dried prunes and tomato paste have separate tolerances).

Usage Data

In order to refine the dietary exposure estimates for acetamiprid, HED requested a Screening 

Level Usage Analysis (SLUA), which was conducted by the Biological and Economic Analysis 

Division (BEAD), 6/11/09. The SLUA includes estimates of maximum %CT for the acute 

assessment and average %CT for determining chronic exposure. Commodities with the most 

significant acetamiprid usage in terms of maximum %CT include pears (60%), apples (30%), 

celery (45%), and lettuce (20%). Commodities with the most significant usage in terms of lbs ai 

applied include apples (10,000), cotton (20,000), and pears (5,000). The SLUA is included as 

Attachment 3.

Table 3. Percent Crop Treated Data Used in DEEM

Commodity Avg Max

Apples 20 30

Broccoli 5 15
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Table 3. Percent Crop Treated Data Used in DEEM

Commodity Avg Max

Cabbage 5 10

Cauliflower 10 15

Celery 25 45

Cotton 5 5

Grapefruit 2.5 5

1

Lemons 5 100

Lettuce 10 20

Oranges 2.5 5

Peaches 1 2.5

Pears 35 60

Peppers 2.5 5

Potatoes 2.5 2.5

Pumpkins 1 2.5

Spinach 5 15

Squash 2.5 2.5

1 - The residue distribution file for oranges which used 5% CT was also used for grapefruit. This was higher 

than the 2.5% CT for grapefruit estimated by BEAD and is more conservative.

For the acute analysis, maximum %CT was incorporated into RDFs for the commodities in the 

above table. For the chronic analysis, average %CT was included (as adjustment factor 2) for the 

commodities listed in the table above.

Incorporation of Potential Residues in Drinking Water

In a memo dated 6/10/09 [D. Lieu, D364248], EFED notified RD that new drinking water 

estimates would not be provided for the proposed use on red clover (grown for seed only), grape, 

and tomato (greenhouse) because the drinking water estimates derived from the uses on citrus and 

tree nuts reflect the maximum use patterns for acetamiprid.

In conjunction with the uses on citrus and tree nuts, the Environmental Fate and Effects Division 

(EFED) prepared an estimate of potential residues in drinking water [G. Orrick, Tier I Drinking 

Water Exposure Assessment for Acetamiprid on Cucurbit, Stone Fruit and Tree Nut Crop Groups, 

6/21/05, D303582]. EFED stated in a June 10, 2009 memorandum (D364248, D. Lieu) that this 

assessment was still valid and should be used to assess the proposed uses on red clover (grown for 

seed), grape, and tomato (greenhouses). Estimated drinking water concentrations for acetamiprid 

in surface water were generated using the FIRST (FQPA Index Reservoir Screening Tool, v. 1.0) 

Model. The results of the model reflect potential residues in a small drinking water reservoir 

surrounded by a runoff-prone watershed, assuming maximum pesticide application rates and no

buffer between the reservoir and treated fields. Acetamiprid residues in ground water sources of 
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drinking water were estimated using the screening regression model SCI-GROW (Screening 

Concentration In Ground Water, v. 2.3). The SCI-GROW residue estimate is based on 

environmental fate properties of the pesticide, maximum application rates, and existing data from 

small-scale prospective ground-water monitoring studies in vulnerable sites.

For surface water, the maximum application rate for the existing use of acetamiprid on citrus was 

used to provide model estimates of drinking water concentrations; for ground water, the proposed 

use on tree nut crops was used. However, since modeled surface water residues were 

considerably higher than ground water residues, only the surface water residues were used 

quantitatively in the dietary (food + water) assessment.

Table 4. Tier I Analysis

1-in-10-year EDWCs in surface water and ground water for acetamiprid.

Drinking Water 

Source

Maximum Use Pattern Exposure EDWC

Surface water Citrus fruit Peak 20.1 ppb

Annual average 4.9 ppb

Ground water Tree nut Peak & annual 

average

 1.6 ppt

For the acute assessment, an estimated drinking water concentration of 20.1 ppb was entered into 

the DEEMTM-FCID Model for “water, direct, all sources” and “water, indirect, all sources.” For 

the chronic assessment, the value of 4.9 ppb was used. The ground water estimate of 1.6 ppt was 

much lower than surface water residues; therefore, dietary exposure and risk calculated using 

surface water residues are considered protective of potential exposure through ground water.

III. Exposure Model and Consumption Information

Acetamiprid acute and chronic dietary exposure assessments were conducted using the Dietary

Exposure Evaluation Model software with the Food Commodity Intake Database DEEMFCIDTM,Version 2.03 which incorporates consumption data from USDA’s Continuing Surveys of 

Food Intakes by Individuals (CSFII), 1994-1996 and 1998. The 1994-96, 98 data are based on the 

reported consumption of more than 20,000 individuals over two non-consecutive survey days. 

Foods “as consumed” (e.g., apple pie) are linked to EPA-defined food commodities (e.g. apples, 

peeled fruit - cooked; fresh or N/S; baked; or wheat flour - cooked; fresh or N/S, baked) using 

publicly available recipe translation files developed jointly by USDA/ARS and EPA. For chronic 

exposure assessment, consumption data are averaged for the entire U.S. population and within 

population subgroups, but for acute exposure assessment are retained as individual consumption 

events. Based on analysis of the 1994-96, 98 CSFII consumption data, which took into account 

dietary patterns and survey respondents, HED concluded that it is most appropriate to report risk 

for the following population subgroups: the general U.S. population, all infants (<1 year old), 

children 1-2, children 3-5, children 6-12, youth 13-19, adults 20-49, females 13-49, and adults 
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50+ years old.

For chronic dietary exposure assessment, an estimate of the residue level in each food or foodform (e.g., orange or orange juice) on the food commodity residue list is multiplied by the average 

daily consumption estimate for that food/food form to produce a residue intake estimate. The 

resulting residue intake estimate for each food/food form is summed with the residue intake 

estimates for all other food/food forms on the commodity residue list to arrive at the total average 

estimated exposure. Exposure is expressed in mg/kg body weight/day and as a percent of the 

cPAD. This procedure is performed for each population subgroup.

For acute exposure assessments, individual one-day food consumption data are used on an 

individual-by-individual basis. The reported consumption amounts of each food item can be 

multiplied by a residue point estimate and summed to obtain a total daily pesticide exposure for a 

deterministic exposure assessment, or “matched” in multiple random pairings with residue values 

and then summed in a probabilistic assessment. The resulting distribution of exposures is 

expressed as a percentage of the aPAD on both a user (i.e., only those who reported eating 

relevant commodities/food forms) and a per-capita (i.e., those who reported eating the relevant 

commodities as well as those who did not) basis. In accordance with HED policy, per capita 

exposure and risk are reported for all tiers of analysis. However, for tiers 1 and 2, any significant 

differences in user vs. per capita exposure and risk are specifically identified and noted in the risk 

assessment.

IV. Toxicological Information

Doses and endpoints selected for acute and chronic dietary exposure and risk assessments are 

summarized as shown in Table 5, below. Details regarding hazard characterization and endpoint 

selection can be found in the risk assessment associated with the proposed uses [D369474, Dennis 

McNeilly, Dec 1, 2009].

Table 5. Acetamiprid Toxicological Doses/Endpoints for Dietary Risk Assessment.

Exposure 

Scenario

Point of 

Departure

Uncertainty/FQPA 

Safety Factors

RfD, PAD, Level of 

Concern 

Study and Toxicological 

Effects

Acute Dietary

[All Populations]

NOAEL=10.0

mg/kg/day

UFA= 10x

UFH= 10x

FQPA SF= 1x

Acute RfD = 0.10

mg/kg/day

aPAD = 0.10

mg/kg/day

Developmental Neurotox., Rat

LOAEL = 45.0 mg/kg/day 

based on decreased startle 

response on PND20/60 in males

Co Critical study -

Acute Neurotox., Rat

LOAEL = 30 mg/kg/day based 

on reduced locomotor activity in 

males.
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Table 5. Acetamiprid Toxicological Doses/Endpoints for Dietary Risk Assessment.

Exposure 

Scenario

Point of 

Departure

Uncertainty/FQPA 

Safety Factors

RfD, PAD, Level of 

Concern 

Study and Toxicological 

Effects

Chronic Dietary

[all populations]

NOAEL = 7.1 

mg/kg/day

UFA= 10x

UFH= 10x

FQPA SF= 1x

Chronic RfD =

0.071 mg/kg/day

cPAD = 0.071 

mg/kg/day

Chronic/oncogenicity, Rat

LOAEL= 17.5 mg/kg/day based 

on reduced body weight and 

body weight gain (♀) and 

hepatocellular vacuolation (♂).

Cancer (All 

routes)

Not likely to be a human carcinogen.

V. Results/Discussion

As stated above, for acute and chronic assessments, HED is concerned when dietary risk exceeds 

100% of the PAD. For both the acute and chronic analyses, the estimated dietary exposures are 

below HED’s level of concern for all population subgroups; the most highly exposed population 

subgroup for both acute and chronic durations is children 1-2 years old.

Acute dietary exposure estimates at the 99.9th percentile are below HED’s level of concern for the 

general US population and all other population subgroups. For the US population, the estimated 

exposure of 0.024 mg/kg/day corresponds to 24% aPAD; for children 1-2 years old, the estimated 

exposure of 0.043 mg/kg/day corresponds to an acute dietary risk of 43% aPAD.

Chronic dietary exposure to acetamiprid is below HED’s level of concern for the US population 

and all other population subgroups. For the general US population, an estimated exposure of 

0.0028 mg/kg/day corresponds to 4% of the chronic population adjusted dose (cPAD); children 1-

2 years old were the highest exposed population subgroup, with an estimate of 0.010 mg/kg/day, 

or 15 % cPAD. Risks for all population subgroups are less than 100 % cPAD, and are not of 

concern.

The results of the acute and chronic analyses are shown in Tables 6 and 7.

Table 6. Results of Acetamiprid Acute Dietary (Food + Water) Exposure Analysis.

Population Subgroup aPAD 

(mg/kg/day)

95th Percentile 99th Percentile 99.9th Percentile

Exposure 

(mg/kg/day) % aPAD Exposure (mg/kg/day) % aPAD Exposure (mg/kg/day) % aPAD

General U.S. Population 0.10 0.006752 6.8 0.012367 12 0.023768 24

All Infants (< 1 year old) 0.10 0.012043 12 0.020075 20 0.031227 31

Children 1-2 years old 0.10 0.016770 17 0.025337 25 0.042928 43

Children 3-5 years old 0.10 0.012277 12 0.020279 20 0.034282 34

Children 6-12 years old 0.10 0.007509 7.5 0.013299 13 0.024123 24
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Table 6. Results of Acetamiprid Acute Dietary (Food + Water) Exposure Analysis.

Population Subgroup aPAD 

(mg/kg/day)

95th Percentile 99th Percentile 99.9th Percentile

Exposure 

(mg/kg/day) % aPAD Exposure (mg/kg/day) % aPAD Exposure (mg/kg/day) % aPAD

Youth 13-19 years old 0.10 0.004686 4.7 0.007810 7.8 0.017682 18

Adults 20-49 years old 0.10 0.004600 4.6 0.007685 7.7 0.015543 16

Adults 50+ years old 0.10 0.004671 4.7 0.007822 7.8 0.013291 13

Females 13-49 years old 0.10 0.004632 4.6 0.007277 7.3 0.013133 13

Table 7. Summary of Dietary (Food + Water) Exposure and Risk for Acetamiprid

Population Subgroup

Acute Dietary

(99.9th Percentile) Chronic Dietary

Dietary Exposure 

(mg/kg/day) % aPAD Dietary Exposure (mg/kg/day) % cPAD

General U.S. Population 0.023768 24 0.002835 4.0

All Infants (< 1 year old) 0.031227 31 0.005206 7.3

Children 1-2 years old 0.042928 43 0.010358 15

Children 3-5 years old 0.034282 34 0.007296 10

Children 6-12 years old 0.024123 24 0.004055 5.7

Youth 13-19 years old 0.017682 18 0.002170 3.1

Adults 20-49 years old 0.015543 16 0.002031 2.9

Adults 50+ years old 0.013291 13 0.002130 3.0

Females 13-49 years old 0.013133 13 0.002057 2.9

VI. Characterization of Inputs/Outputs

The acute dietary exposure assessment for acetamiprid is somewhat refined, since field trial 

residue distributions were used in the probabilistic assessment, and percent crop treated 

information was incorporated for some commodities. In addition, empirical processing factors for 

various processed commodities, especially juices, provided an additional measure of refinement. 

However, the assessment is still somewhat conservative because tolerance-level residues were 

used for proposed uses and some of the existing uses, as well as livestock commodities. 

Additional refinements could be made to the assessment with the use of additional field trial 

residue data. Even though the acute probabilistic assessment has not been completely refined, 

acute dietary exposure and risk estimates for acetamiprid are below HED’s level of concern of 

100 % aPAD.

The chronic dietary exposure assessment is unrefined, with the exception of the use of %CT data 

cited in Table 3. For all commodities, tolerance level residues were used, and DEEM 7.81 default 
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processing factors were applied. Further refinements are possible in the future, including the use 

of average field trial residues, empirical processing factors and additional %CT refinements.

VII. Conclusions

Acute and chronic dietary (food + water) risks for acetamiprid are below HED’s level of concern 

for dietary exposure and risk. Children 1-2 years old are the most highly exposed population 

subgroup, with risks of 43% aPAD for acute and 15% cPAD for chronic. Risks were lower for all 

other population subgroups, including the general US population. The acute and chronic dietary

exposure assessments support the new uses proposed for acetamiprid.

VIII. List of Attachments

Attachment 1. Acetamiprid Residue Distribution Files

Attachment 2. Acetamiprid Screening Level Usage Analysis (SLUA)

Attachment 4. Acute Residue Input Files

Attachment 5 Summary of Acute Results

Attachment 6. Chronic Residue Input File

Attachment 7. Summary of Chronic Results
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Attachment 1. Acetamiprid Residue Distribution Files

Acetamiprid/Apple

TOTALZ=149

Est. Max. %CT = 30

MRID No. 44988626

0.15, 0.16, 0.59, 0.59 0.25

0.29, 0.11, 0.16, 0.12, 0.12

0.24, 0.32, 0.17, 0.18, 0.20

0.23, 0.13, 0.14, 0.21, 0.28

0.09, 0.15, 0.24, 0.28, 0.22

0.39, 0.17, 0.20, 0.45, 0.64

0.22, 0.28, 0.23, 0.23, 0.21

0.25, 0.30, 0.30, 0.25, 0.26

0.26, 0.36, 0.14, 0.16, 0.23

0.27, 0.08, 0.10, 0.30, 0.34

0.25, 0.29, 0.08 0.10, 0.10

0.23, 0.18, 0.21, 0.61, 0.71

0.34, 0.35, 0.21, 0.24

Acetamiprid/Broccoli

Estimated max %CT = 15

TOTALZ=130

MRID No. 44988631

0.02, 0.04, 0.04, 0.05, 0.01

0.01, 0.005, 0.02, 0.01, 0.02

0.005, 0.01, 0.07, 0.11, 0.18

0.25, 0.02, 0.097, 0.10, 0.080

0.092, 0.081, 0.10

Acetamiprid/Cabbage

w/out wrapper leaves, 10 %CT

TOTALZ=180

MRID No. 44988631

0.005, 0.02, 0.005, 0.01, 0.005

0.005, 0.005, 0.005, 0.03, 0.03

0.005, 0.005, 0.01, 0.02, 0.02

0.02, 0.05, 0.05, 0.03, 0.03

Acetamiprid/Celery

Estimated Max. %CT = 45

TOTALZ=20

MRID No. 44988603

0.775, 0.780, 0.167, 0.182

0.396, 0.426, 0.287, 0.352

0.250, 0.290, 0.255, 0.281

0.499, 0.517, 0.068, 0.084

Acetamiprid/Cucurbit

Assume 100%CT

MRID No. 46265701

0.024, 0.038, 0.015, 0.026

0.024, 0.030, 0.038, 0.045

0.082, 0.091, 0.017, 0.019

0.070, 0.090, 0.035, 0.076

0.011, 0.026, 0.011, 0.021

0.035, 0.037, 0.065, 0.142, 

0.091, 0.094, 0.075, 0.136

0.053, 0.068, 0.166, 0.221

0.004, 0.075

Acetamiprid/Grape

Assume 100% CT

TOTALZ=0

MRID No. 47716902

0.05, 0.05, 0.03, 0.03, 0.01, 

0.01, 0.08, 0.08, 0.17, 0.15, 

0.08, 0.09, 0.08, 0.08, 0.2,

0.21, 0.24, 0.25, 0.1, 0.11,

0.06, 0.06, 0.22, 0.22, 0.04, 

0.04, 0.07, 0.06, 0.04, 0.03, 

0.15, 0.15, 0.24, 0.22, 0.13,

0.13

Acetamiprid/Head Lettuce

MRID No. 44988603

Estimated Max. %CT = 20%

TOTALZ=72

0.155, 0.184, 0.253, 0.294, 

0.017, 0.018, 0.047, 0.057

0.005, 0.005, 0.060, 0.061

0.014, 0.014, 0.010, 0.010

0.074, 0.14

Acetamiprid/Leaf Lettuce

Estimated Maximum %CT=20

TOTALZ=80

MRID No. 44988603

0.716, 1.02, 0.108, 0.123

0.565, 0.646, 0.265, 0.330

0.374, 0.449, 0.848, 1.07

0.098, 0.114, 0.435, 0.479

0.12, 0.18, 0.074, 0.14

Acetamiprid/Orange

TOTALZ=1235

Est. max %CT=5

MRID No. 4498611

0.14, 0.15, 0.11, 0.12, 0.09

0.13, 0.19, 0.29, 0.18, 0.21

0.29, 0.097, 0.11, 0.15, 0.21

0.20, 0.20, 0.058, 0.084, 0.088

0.15, 0.11, 0.15, 0.094, 0.12

0.19, 0.20, 0.19, 0.21, 0.26

0.29, 0.21, 0.23, 0.025, 0.025

0.13, 0.14, 0.081, 0.12, 0.14

0.14, 0.083, 0.12, 0.025, 0.025, 

0.025, 0.025, 0.025, 0.098

0.23, 0.27, 0.12, 0.14, 0.079

0.096, 0.087, 0.12, 0.12, 0.16

0.31, 0.37, 0.16, 0.31, 0.26

0.39

Acetamiprid/Peach

Assume 2.5%CT

TOTALZ=1014

MRID No. 46265702

0.294, 0.344, 0.311, 0.565

0.184, 0.225, 0.163, 0.188

0.182, 0.223, 0.117, 0.138

0.153, 0.166, 0.283, 0.387

0.205, 0.233, 0.192, 0.240

0.211, 0.242, 0.0927, 0.133

0.186, 0.199

Acetamiprid/Pear

TOTALZ=42

Est. Max. %CT = 60

MRID No. 44988626

0.15, 0.16, 0.59, 0.59 0.25

0.29, 0.11, 0.16, 0.12, 0.12

0.24, 0.32, 0.17, 0.18, 0.20

0.23, 0.13, 0.14, 0.21, 0.28

0.09, 0.15, 0.24, 0.28, 0.22

0.39, 0.17, 0.20, 0.45, 0.64

0.22, 0.28, 0.23, 0.23, 0.21

0.25, 0.30, 0.30, 0.25, 0.26

0.26, 0.36, 0.14, 0.16, 0.23

0.27, 0.08, 0.10, 0.30, 0.34

0.25, 0.29, 0.08 0.10, 0.10

0.23, 0.18, 0.21, 0.61, 0.71

0.34, 0.35, 0.21, 0.24

Acetamiprid/Peppers

Estimated Max. %CT = 5

TOTALZ=570

MRID No. 44988616

0.005, 0.005, 0.01, 0.02, 0.01

0.01, 0.03, 0.05, 0.03, 0.04

0.01, 0.01, 0.02, 0.03, 0.02

0.02, 0.08, 0.09, 0.03, 0.03

0.06, 0.07, 0.04, 0.07, 0.05

0.06, 0.12, 0.16, 0.08, 0.08
Acetamiprid Dietary Exposure and Risk Assessment DP No.: 372890

PC Code: 099050

Page 13 of 28

Acetamiprid/Plum

Assume 100%CT

TOTALZ=0

MRID No. 46265702

0.108, 0.116, 0.0648, 0.119

0.0139, 0.0238, 0.0103, 0.0154

0.0515, 0.0624, 0.0401, 0.0429

0.0305, 0.0458, 0.0258, 0.0392

Acetamiprid/Spinach

Assume 15%CT

TOTALZ=125

MRID No. 44988603

0.034, 0.037, 0.184, 0.238

0.026, 0.036, 1.06, 1.20, 2.46

2.58, 0.516, 0.588, 1.95, 2.22

0.463, 0.466, 0.15, 0.23, 0.18

0.18, 0.19, 0.22

Acetamiprid/Tomatoes

Assume %CT=100

TOTALZ=0

MRIDs 44988616/47716903

0.01, 0.01, 0.005, 0.005, 0.005, 

0.005, 0.01, 0.04, 0.08, 0.11

0.005, 0.01, 0.07, 0.08, 0.06

0.11, 0.02, 0.03, 0.02, 0.04

0.02, 0.02, 0.03, 0.03, 0.05

0.07, 0.03, 0.05, 0.06, 0.06

0.03, 0.05, 0.02, 0.02, 0.005

0.005, 0.047, 0.052, 0.005

0.005, 0.026, 0.028

Summary of Residue Distribution Files (RDF) listed in C:\Documents and Settings\Dmcneill\My 

Documents\Acetamiprid\PRIAacetamiprid_acuteAR.r98

RDF File N residues N residues N Zeros

 # Name w freq's w/o freq's 

---- ------------ ---------- ---------- -------

 1 orange.RDF 0 65 1297

 2 Apple.RDF 0 64 149

 3 spinach.rdf 0 22 124

 4 cabbage.RDF 0 20 180 

 5 peach.RDF 0 26 1114

 6 Plum.RDF 0 16 0 

 7 Pear.RDF 0 64 43

 8 Broccoli.RDF 0 23 130

 9 Celery.RDF 0 16 20

 10 HeadLettuce.RDF 0 18 72

 11 LeafLettuce.RDF 0 20 80 

 12 cucurbit.RDF 0 34 0 

 13 Grapes.RDF 0 36 0

 14 Peppers.RDF 0 30 570

 15 Tomatoes.RDF 0 42 0
Acetamiprid Dietary Exposure and Risk Assessment DP No.: 372890

PC Code: 099050

Page 14 of 28

Attachment 2. Acetamiprid Screening Level Usage Analysis (SLUA)
Acetamiprid Dietary Exposure and Risk Assessment DP No.: 372890

PC Code: 099050

Page 15 of 28
Acetamiprid Dietary Exposure and Risk Assessment DP No.: 372890

PC Code: 099050

Page 16 of 28

Attachment 3. DEEM-FCIDTM Acute Residue Input File

U.S. Environmental Protection Agency Ver. 2.02

DEEM-FCID Acute analysis for ACETAMIPRID

Residue file name: C:\Documents and Settings\dmcneill\My 

Documents\Actemidprid\PRIAacetamiprid_acuteAR_2010.R98

Analysis Date 01-14-2010 Residue file dated: 01-14-2010/06:49:51/8

Reference dose: aRfD = 0.1 mg/kg bw/day NOEL = 10 mg/kg bw/day

Comment: Acute/Chronic - UFs = 100

--------------------------------------------------------------------------------

RDL indices and parameters for Monte Carlo Analysis:

Index Dist Parameter #1 Param #2 Param #3 Comment

 # Code 

----- ---- ------------ ----------- ----------- ----------

 1 6 orange.RDF

 2 6 Apple.RDF

 3 6 spinach.rdf

 4 6 cabbage.RDF

 5 6 peach.RDF

 6 6 Plum.RDF

 7 6 Pear.RDF

 8 6 Broccoli.RDF

 9 6 Celery.RDF

 10 6 HeadLettuce.RDF

 11 6 LeafLettuce.RDF

 12 6 cucurbit.RDF

 13 6 Grapes.RDF

 14 6 Peppers.RDF

 15 6 Tomatoes.RDF

 EPA Crop Food Name Def Res Adj.Factors RDL Comment

 Code Grp (ppm) #1 #2 Pntr

-------- ---- ------------------------------- ---------- ------ ------ --- -------

14000030 14 Almond 0.100000 1.000 1.000 

14000031 14 Almond-babyfood 0.100000 1.000 1.000 

14000040 14 Almond, oil 0.100000 1.000 1.000 

14000041 14 Almond, oil-babyfood 0.100000 1.000 1.000 

04010050 4A Amaranth, leafy 3.000000 1.000 1.000 

11000070 11 Apple, fruit with peel 1.000000 1.000 1.000 2 

11000080 11 Apple, peeled fruit 1.000000 1.000 1.000 2 

11000081 11 Apple, peeled fruit-babyfood 1.000000 1.000 1.000 2 

11000090 11 Apple, dried 1.000000 8.000 1.000 2 

11000091 11 Apple, dried-babyfood 1.000000 8.000 1.000 2 

11000100 11 Apple, juice 1.000000 0.880 1.000 2 

11000101 11 Apple, juice-babyfood 1.000000 0.880 1.000 2 

11000110 11 Apple, sauce 1.000000 1.000 1.000 2 

11000111 11 Apple, sauce-babyfood 1.000000 1.000 1.000 2 

12000120 12 Apricot 1.200000 1.000 1.000 6 

12000121 12 Apricot-babyfood 1.200000 1.000 1.000 6 

12000130 12 Apricot, dried 1.200000 2.900 1.000 6 

12000140 12 Apricot, juice 1.200000 1.000 1.000 6 

12000141 12 Apricot, juice-babyfood 1.200000 1.000 1.000 6 

01030150 1CD Arrowroot, flour 0.010000 1.000 1.000 

01030151 1CD Arrowroot, flour-babyfood 0.010000 1.000 1.000 

01030170 1CD Artichoke, Jerusalem 0.010000 1.000 1.000 

04010180 4A Arugula 3.000000 1.000 1.000 

09020210 9B Balsam pear 0.500000 1.000 1.000 

06020310 6B Bean, broad, succulent 0.400000 1.000 1.000 

06020330 6B Bean, cowpea, succulent 0.400000 1.000 1.000 

06020370 6B Bean, lima, succulent 0.400000 1.000 1.000 

06010430 6A Bean, snap, succulent 0.600000 1.000 1.000 

06010431 6A Bean, snap, succulent-babyfood 0.600000 1.000 1.000 

21000440 M Beef, meat 0.100000 1.000 1.000 

21000441 M Beef, meat-babyfood 0.100000 1.000 1.000 

21000450 M Beef, meat, dried 0.100000 1.920 1.000 

21000460 M Beef, meat byproducts 0.200000 1.000 1.000 

21000461 M Beef, meat byproducts-babyfood 0.200000 1.000 1.000 
Acetamiprid Dietary Exposure and Risk Assessment DP No.: 372890

PC Code: 099050

Page 17 of 28

21000470 M Beef, fat 0.100000 1.000 1.000 

21000471 M Beef,fat-babyfood 0.100000 1.000 1.000 

21000480 M Beef, kidney 0.200000 1.000 1.000 

21000490 M Beef, liver 0.200000 1.000 1.000 

21000491 M Beef, liver-babyfood 0.200000 1.000 1.000 

13010550 13A Blackberry 1.600000 1.000 1.000 

13010560 13A Blackberry, juice 1.600000 1.000 1.000 

13010561 13A Blackberry, juice-babyfood 1.600000 1.000 1.000 

13020570 13B Blueberry 1.600000 1.000 1.000 

13020571 13B Blueberry-babyfood 1.600000 1.000 1.000 

13010580 13A Boysenberry 1.600000 1.000 1.000 

14000590 14 Brazil nut 0.100000 1.000 1.000 

05010610 5A Broccoli 1.200000 1.000 1.000 8 

05010611 5A Broccoli-babyfood 1.200000 1.000 1.000 8 

05010620 5A Broccoli, Chinese 1.200000 1.000 1.000 8 

05020630 5B Broccoli raab 1.200000 1.000 1.000 

05010640 5A Brussels sprouts 1.200000 1.000 1.000 

14000680 14 Butternut 0.100000 1.000 1.000 

05010690 5A Cabbage 1.200000 1.000 1.000 4 

05020700 5B Cabbage, Chinese, bok choy 1.200000 1.000 1.000 

05010710 5A Cabbage, Chinese, napa 1.200000 1.000 1.000 

05010720 5A Cabbage, Chinese, mustard 1.200000 1.000 1.000 

09010750 9A Cantaloupe 0.500000 1.000 1.000 

04020760 4B Cardoon 3.000000 1.000 1.000 

09010800 9A Casaba 0.500000 1.000 1.000 

14000810 14 Cashew 0.100000 1.000 1.000 

01030820 1CD Cassava 0.010000 1.000 1.000 

01030821 1CD Cassava-babyfood 0.010000 1.000 1.000 

05010830 5A Cauliflower 1.200000 1.000 1.000 

04020850 4B Celery 3.000000 1.000 1.000 9 

04020851 4B Celery-babyfood 3.000000 1.000 1.000 9 

04020860 4B Celery, juice 3.000000 1.000 1.000 9 

04020870 4B Celtuce 3.000000 1.000 1.000 

09020880 9B Chayote, fruit 0.500000 1.000 1.000 

12000900 12 Cherry 1.200000 1.000 1.000 

12000901 12 Cherry-babyfood 1.200000 1.000 1.000 

12000910 12 Cherry, juice 1.200000 1.500 1.000 

12000911 12 Cherry, juice-babyfood 1.200000 1.500 1.000 

14000920 14 Chestnut 0.100000 1.000 1.000 

40000930 P Chicken, meat 0.010000 1.000 1.000 

40000931 P Chicken, meat-babyfood 0.010000 1.000 1.000 

40000940 P Chicken, liver 0.050000 1.000 1.000 

40000950 P Chicken, meat byproducts 0.050000 1.000 1.000 

40000951 P Chicken, meat byproducts-babyfoo 0.050000 1.000 1.000 

40000960 P Chicken, fat 0.010000 1.000 1.000 

40000961 P Chicken, fat-babyfood 0.010000 1.000 1.000 

40000970 P Chicken, skin 0.010000 1.000 1.000 

40000971 P Chicken, skin-babyfood 0.010000 1.000 1.000 

09021020 9B Chinese waxgourd 0.500000 1.000 1.000 

19011030 19A Chive 4.500000 1.000 1.000 

04011040 4A Chrysanthemum, garland 3.000000 1.000 1.000 

10001060 10 Citrus citron 0.500000 1.000 1.000 

10001070 10 Citrus hybrids 0.500000 1.000 1.000 

10001080 10 Citrus, oil 0.500000 1.000 1.000 

05021170 5B Collards 1.200000 1.000 1.000 

95001280 O Cottonseed, oil 0.600000 1.000 1.000 

95001281 O Cottonseed, oil-babyfood 0.600000 1.000 1.000 

11001290 11 Crabapple 1.000000 1.000 1.000 

95001300 O Cranberry 0.600000 1.000 1.000 

95001301 O Cranberry-babyfood 0.600000 1.000 1.000 

95001310 O Cranberry, dried 0.600000 1.000 1.000 

95001320 O Cranberry, juice 0.600000 1.100 1.000 

95001321 O Cranberry, juice-babyfood 0.600000 1.100 1.000 

04011330 4A Cress, garden 3.000000 1.000 1.000 

04011340 4A Cress, upland 3.000000 1.000 1.000 

09021350 9B Cucumber 0.500000 1.000 1.000 12 

13021360 13B Currant 1.600000 1.000 1.000 

13021370 13B Currant, dried 1.600000 1.000 1.000 
Acetamiprid Dietary Exposure and Risk Assessment DP No.: 372890

PC Code: 099050

Page 18 of 28

04011380 4A Dandelion, leaves 3.000000 1.000 1.000 

01031390 1CD Dasheen, corm 0.010000 1.000 1.000 

13011420 13A Dewberry 1.600000 1.000 1.000 

70001450 P Egg, whole 0.010000 1.000 1.000 

70001451 P Egg, whole-babyfood 0.010000 1.000 1.000 

70001460 P Egg, white 0.010000 1.000 1.000 

70001461 P Egg, white (solids)-babyfood 0.010000 1.000 1.000 

70001470 P Egg, yolk 0.010000 1.000 1.000 

70001471 P Egg, yolk-babyfood 0.010000 1.000 1.000 

08001480 8 Eggplant 0.200000 1.000 1.000 

13021490 13B Elderberry 1.600000 1.000 1.000 

04011500 4A Endive 3.000000 1.000 1.000 

04021520 4B Fennel, Florence 3.000000 1.000 1.000 

14001550 14 Filbert 0.100000 1.000 1.000 

14001560 14 Filbert, oil 0.100000 1.000 1.000 

03001640 3 Garlic 0.020000 1.000 1.000 

03001650 3 Garlic, dried 0.020000 1.000 1.000 

03001651 3 Garlic, dried-babyfood 0.020000 1.000 1.000 

01031660 1CD Ginger 0.010000 1.000 1.000 

01031661 1CD Ginger-babyfood 0.010000 1.000 1.000 

01031670 1CD Ginger, dried 0.010000 1.000 1.000 

23001690 M Goat, meat 0.100000 1.000 1.000 

23001700 M Goat, meat byproducts 0.200000 1.000 1.000 

23001710 M Goat, fat 0.100000 1.000 1.000 

23001720 M Goat, kidney 0.200000 1.000 1.000 

23001730 M Goat, liver 0.200000 1.000 1.000 

13021740 13B Gooseberry 1.600000 1.000 1.000 

95001750 O Grape 0.350000 1.000 1.000 13 

95001760 O Grape, juice 0.350000 1.000 1.000 13 

95001761 O Grape, juice-babyfood 0.350000 1.000 1.000 13 

95001770 O Grape, leaves 0.350000 1.000 1.000 13 

95001780 O Grape, raisin 0.350000 0.900 1.000 13 

95001790 O Grape, wine and sherry 0.350000 1.000 1.000 13 

10001800 10 Grapefruit 0.500000 1.000 1.000 1 

10001810 10 Grapefruit, juice 0.500000 0.160 1.000 1 

14001850 14 Hickory nut 0.100000 1.000 1.000 

09011870 9A Honeydew melon 0.500000 1.000 1.000 

24001890 M Horse, meat 0.100000 1.000 1.000 

13021910 13B Huckleberry 1.600000 1.000 1.000 

05021940 5B Kale 1.200000 1.000 1.000 

95001950 O Kiwifruit 0.350000 1.000 1.000 

05011960 5A Kohlrabi 1.200000 1.000 1.000 

10001970 10 Kumquat 0.500000 1.000 1.000 

03001980 3 Leek 4.500000 1.000 1.000 

10001990 10 Lemon 0.500000 1.000 1.000 

10002000 10 Lemon, juice 0.500000 2.000 1.000 

10002001 10 Lemon, juice-babyfood 0.500000 2.000 1.000 

10002010 10 Lemon, peel 0.500000 1.000 1.000 

04012040 4A Lettuce, head 3.000000 1.000 1.000 10 

04012050 4A Lettuce, leaf 3.000000 1.000 1.000 11 

10002060 10 Lime 0.500000 1.000 1.000 

10002070 10 Lime, juice 0.500000 2.000 1.000 

10002071 10 Lime, juice-babyfood 0.500000 2.000 1.000 

13012080 13A Loganberry 1.600000 1.000 1.000 

11002100 11 Loquat 1.000000 1.000 1.000 

14002130 14 Macadamia nut 0.100000 1.000 1.000 

28002210 M Meat, game 0.100000 1.000 1.000 

27002220 D Milk, fat 0.100000 1.000 1.000 

27002221 D Milk, fat - baby food/infant for 0.100000 1.000 1.000 

27012230 D Milk, nonfat solids 0.100000 1.000 1.000 

27012231 D Milk, nonfat solids-baby food/in 0.100000 1.000 1.000 

27022240 D Milk, water 0.100000 1.000 1.000 

27022241 D Milk, water-babyfood/infant form 0.100000 1.000 1.000 

27032251 D Milk, sugar (lactose)-baby food/ 0.100000 1.000 1.000 

05022290 5B Mustard greens 1.200000 1.000 1.000 

12002300 12 Nectarine 1.200000 1.000 1.000 5 

08002340 8 Okra 0.200000 1.000 1.000 

03002370 3 Onion, dry bulb 0.020000 1.000 1.000 
Acetamiprid Dietary Exposure and Risk Assessment DP No.: 372890

PC Code: 099050

Page 19 of 28

03002371 3 Onion, dry bulb-babyfood 0.020000 1.000 1.000 

03002380 3 Onion, dry bulb, dried 0.020000 9.000 1.000 

03002381 3 Onion, dry bulb, dried-babyfood 0.020000 9.000 1.000 

03002390 3 Onion, green 4.500000 1.000 1.000 

10002400 10 Orange 0.500000 1.000 1.000 1 

10002410 10 Orange, juice 0.500000 0.160 1.000 1 

10002411 10 Orange, juice-babyfood 0.500000 0.160 1.000 1 

10002420 10 Orange, peel 0.500000 1.000 1.000 1 

04012480 4A Parsley, leaves 3.000000 1.000 1.000 

06022550 6B Pea, succulent 0.400000 1.000 1.000 

06022551 6B Pea, succulent-babyfood 0.400000 1.000 1.000 

06012570 6A Pea, edible podded, succulent 0.600000 1.000 1.000 

06022590 6B Pea, pigeon, succulent 0.400000 1.000 1.000 

12002600 12 Peach 1.200000 1.000 1.000 5 

12002601 12 Peach-babyfood 1.200000 1.000 1.000 5 

12002610 12 Peach, dried 1.200000 2.900 1.000 5 

12002611 12 Peach, dried-babyfood 1.200000 2.900 1.000 5 

12002620 12 Peach, juice 1.200000 1.000 1.000 5 

12002621 12 Peach, juice-babyfood 1.200000 1.000 1.000 5 

11002660 11 Pear 1.000000 1.000 1.000 7 

11002661 11 Pear-babyfood 1.000000 1.000 1.000 7 

11002670 11 Pear, dried 1.000000 6.250 1.000 7 

11002680 11 Pear, juice 1.000000 0.880 1.000 7 

11002681 11 Pear, juice-babyfood 1.000000 0.880 1.000 7 

14002690 14 Pecan 0.100000 1.000 1.000 

08002700 8 Pepper, bell 0.200000 1.000 1.000 14 

08002701 8 Pepper, bell-babyfood 0.200000 1.000 1.000 14 

08002710 8 Pepper, bell, dried 0.200000 1.000 1.000 14 

08002711 8 Pepper, bell, dried-babyfood 0.200000 1.000 1.000 14 

08002720 8 Pepper, nonbell 0.200000 1.000 1.000 14 

08002721 8 Pepper, nonbell-babyfood 0.200000 1.000 1.000 14 

08002730 8 Pepper, nonbell, dried 0.200000 1.000 1.000 14 

14002820 14 Pistachio 0.100000 1.000 1.000 

12002850 12 Plum 1.200000 1.000 1.000 6 

12002851 12 Plum-babyfood 1.200000 1.000 1.000 6 

12002860 12 Plum, prune, fresh 0.200000 1.000 1.000 6 

12002861 12 Plum, prune, fresh-babyfood 0.200000 1.000 1.000 6 

12002870 12 Plum, prune, dried 0.400000 2.900 1.000 6 

12002871 12 Plum, prune, dried-babyfood 0.400000 2.900 1.000 6 

12002880 12 Plum, prune, juice 0.200000 1.400 1.000 6 

12002881 12 Plum, prune, juice-babyfood 0.200000 1.400 1.000 6 

25002900 M Pork, meat 0.100000 1.000 1.000 

25002901 M Pork, meat-babyfood 0.100000 1.000 1.000 

25002910 M Pork, skin 0.100000 1.000 1.000 

25002920 M Pork, meat byproducts 0.200000 1.000 1.000 

25002921 M Pork, meat byproducts-babyfood 0.200000 1.000 1.000 

25002930 M Pork, fat 0.100000 1.000 1.000 

25002931 M Pork, fat-babyfood 0.100000 1.000 1.000 

25002940 M Pork, kidney 0.200000 1.000 1.000 

25002950 M Pork, liver 0.200000 1.000 1.000 

01032960 1C Potato, chips 0.010000 1.000 1.000 

01032970 1C Potato, dry (granules/ flakes) 0.010000 6.500 1.000 

01032971 1C Potato, dry (granules/ flakes)-b 0.010000 6.500 1.000 

01032980 1C Potato, flour 0.010000 6.500 1.000 

01032981 1C Potato, flour-babyfood 0.010000 6.500 1.000 

01032990 1C Potato, tuber, w/peel 0.010000 1.000 1.000 

01032991 1C Potato, tuber, w/peel-babyfood 0.010000 1.000 1.000 

01033000 1C Potato, tuber, w/o peel 0.010000 1.000 1.000 

01033001 1C Potato, tuber, w/o peel-babyfood 0.010000 1.000 1.000 

60003010 P Poultry, other, meat 0.010000 1.000 1.000 

60003020 P Poultry, other, liver 0.050000 1.000 1.000 

60003030 P Poultry, other, meat byproducts 0.050000 1.000 1.000 

60003040 P Poultry, other, fat 0.010000 1.000 1.000 

60003050 P Poultry, other, skin 0.010000 1.000 1.000 

10003070 10 Pummelo 0.500000 1.000 1.000 

09023080 9B Pumpkin 0.500000 1.000 1.000 

09023090 9B Pumpkin, seed 0.500000 1.000 1.000 

11003100 11 Quince 1.000000 1.000 1.000 
Acetamiprid Dietary Exposure and Risk Assessment DP No.: 372890

PC Code: 099050

Page 20 of 28

29003120 M Rabbit, meat 0.100000 1.000 1.000 

04013130 4A Radicchio 3.000000 1.000 1.000 

05023180 5B Rape greens 1.200000 1.000 1.000 

20003190 20 Rapeseed, oil 0.010000 1.000 1.000 

20003191 20 Rapeseed, oil-babyfood 0.010000 1.000 1.000 

13013200 13A Raspberry 1.600000 1.000 1.000 

13013201 13A Raspberry-babyfood 1.600000 1.000 1.000 

13013210 13A Raspberry, juice 1.600000 1.000 1.000 

13013211 13A Raspberry, juice-babyfood 1.600000 1.000 1.000 

04023220 4B Rhubarb 3.000000 1.000 1.000 

03003380 3 Shallot 0.020000 1.000 1.000 

26003390 M Sheep, meat 0.100000 1.000 1.000 

26003391 M Sheep, meat-babyfood 0.100000 1.000 1.000 

26003400 M Sheep, meat byproducts 0.200000 1.000 1.000 

26003410 M Sheep, fat 0.100000 1.000 1.000 

26003411 M Sheep, fat-babyfood 0.100000 1.000 1.000 

26003420 M Sheep, kidney 0.200000 1.000 1.000 

26003430 M Sheep, liver 0.200000 1.000 1.000 

19023540 19B Spices, other 0.010000 1.000 1.000 

19023541 19B Spices, other-babyfood 0.010000 1.000 1.000 

04013550 4A Spinach 3.000000 1.000 1.000 3 

04013551 4A Spinach-babyfood 3.000000 1.000 1.000 3 

09023560 9B Squash, summer 0.500000 1.000 1.000 12 

09023561 9B Squash, summer-babyfood 0.500000 1.000 1.000 12 

09023570 9B Squash, winter 0.500000 1.000 1.000 12 

09023571 9B Squash, winter-babyfood 0.500000 1.000 1.000 12 

95003590 O Strawberry 0.600000 1.000 1.000 

95003591 O Strawberry-babyfood 0.600000 1.000 1.000 

95003600 O Strawberry, juice 0.600000 1.000 1.000 

95003601 O Strawberry, juice-babyfood 0.600000 1.000 1.000 

01033660 1CD Sweet potato 0.010000 1.000 1.000 

01033661 1CD Sweet potato-babyfood 0.010000 1.000 1.000 

04023670 4B Swiss chard 3.000000 1.000 1.000 

10003690 10 Tangerine 0.500000 1.000 1.000 

10003700 10 Tangerine, juice 0.500000 2.300 1.000 

01033710 1CD Tanier, corm 0.010000 1.000 1.000 

95003720 O Tea, dried 50.000000 1.000 1.000 

95003730 O Tea, instant 50.000000 1.000 1.000 

08003740 8 Tomatillo 0.200000 1.000 1.000 15 

08003750 8 Tomato 0.200000 1.000 1.000 15 

08003751 8 Tomato-babyfood 0.200000 1.000 1.000 15 

08003760 8 Tomato, paste 0.400000 3.000 1.000 15 

08003761 8 Tomato, paste-babyfood 0.400000 3.000 1.000 15 

08003770 8 Tomato, puree 0.200000 1.400 1.000 15 

08003771 8 Tomato, puree-babyfood 0.200000 1.400 1.000 15 

08003780 8 Tomato, dried 0.200000 14.300 1.000 15 

08003781 8 Tomato, dried-babyfood 0.200000 14.300 1.000 15 

08003790 8 Tomato, juice 0.200000 1.500 1.000 15 

50003820 P Turkey, meat 0.010000 1.000 1.000 

50003821 P Turkey, meat-babyfood 0.010000 1.000 1.000 

50003830 P Turkey, liver 0.050000 1.000 1.000 

50003831 P Turkey, liver-babyfood 0.050000 1.000 1.000 

50003840 P Turkey, meat byproducts 0.050000 1.000 1.000 

50003841 P Turkey, meat byproducts-babyfood 0.050000 1.000 1.000 

50003850 P Turkey, fat 0.010000 1.000 1.000 

50003851 P Turkey, fat-babyfood 0.010000 1.000 1.000 

50003860 P Turkey, skin 0.010000 1.000 1.000 

50003861 P Turkey, skin-babyfood 0.010000 1.000 1.000 

01033870 1CD Turmeric 0.010000 1.000 1.000 

05023890 5B Turnip, greens 1.200000 1.000 1.000 

14003910 14 Walnut 0.100000 1.000 1.000 

86010000 O Water, direct, all sources 0.020100 1.000 1.000 

86020000 O Water, indirect, all sources 0.020100 1.000 1.000 

09013990 9A Watermelon 0.500000 1.000 1.000 

09014000 9A Watermelon, juice 0.500000 1.000 1.000 

01034060 1CD Yam, true 0.010000 1.000 1.000 

01034070 1CD Yam bean 0.010000 1.000 1.000 
Acetamiprid Dietary Exposure and Risk Assessment DP No.: 372890

PC Code: 099050

Page 21 of 28
Acetamiprid Dietary Exposure and Risk Assessment DP No.: 372890

PC Code: 099050

Page 22 of 28

Attachment 4. Summary of DEEM-FCIDTM Acute Results

U.S. Environmental Protection Agency Ver. 2.02

DEEM-FCID ACUTE Analysis for ACETAMIPRID (1994-98 data)

Residue file: PRIAacetamiprid_acuteAR_2010.R98 Adjustment factor #2 NOT used.

Analysis Date: 01-14-2010/06:56:20 Residue file dated: 01-14-2010/06:49:51/8

NOEL (Acute) = 10.000000 mg/kg body-wt/day

Daily totals for food and foodform consumption used.

MC iterations = 1000 MC list in residue file MC seed = 10

Run Comment: "Acute/Chronic - UFs = 100"

===============================================================================

Summary calculations (per capita):

 95th Percentile 99th Percentile 99.9th Percentile

Exposure % aRfD MOE Exposure % aRfD MOE Exposure % aRfD MOE 

---------- ------- -------- ---------- ------- -------- ---------- ------- --------

U.S. Population:

 0.006752 6.75 1480 0.012367 12.37 808 0.023768 23.77 420 

All infants:

 0.012043 12.04 830 0.020075 20.08 498 0.031227 31.23 320 

Children 1-2 yrs:

 0.016770 16.77 596 0.025337 25.34 394 0.042928 42.93 232 

Children 3-5 yrs:

 0.012277 12.28 814 0.020279 20.28 493 0.034282 34.28 291 

Children 6-12 yrs:

 0.007509 7.51 1331 0.013299 13.30 751 0.024123 24.12 414 

Youth 13-19 yrs:

 0.004686 4.69 2133 0.007810 7.81 1280 0.017682 17.68 565 

Adults 20-49 yrs:

 0.004600 4.60 2173 0.007685 7.69 1301 0.015543 15.54 643 

Adults 50+ yrs:

 0.004671 4.67 2140 0.007822 7.82 1278 0.013291 13.29 752 

Females 13-49 yrs:

 0.004632 4.63 2158 0.007277 7.28 1374 0.013133 13.13 761 
Acetamiprid Dietary Exposure and Risk Assessment DP No.: 372890

PC Code: 099050

Page 23 of 28

Attachment 5. DEEM-FCIDTM Chronic Residue Input File

U.S. Environmental Protection Agency Ver. 2.00

DEEM-FCID Chronic analysis for ACETAMIPRID 1994-98 data

Residue file: C:\Documents and Settings\dmcneill\My 

Documents\Actemidprid\PRIADNTacetamipridCT_chronic.R98

 Adjust. #2 used

Analysis Date 01-12-2010 Residue file dated: 01-12-2010/08:15:02/8

Reference dose (RfD) = 0.071 mg/kg bw/day

Comment:Acute/Chronic - UFs = 100

--------------------------------------------------------------------------------

Food Crop Residue Adj.Factors Comment

EPA Code Grp Food Name (ppm) 

 #1 #2 

-------- ---- ------------------------------- ---------- ------ ------ -------

14000030 14 Almond 0.100000 1.000 1.000 

14000031 14 Almond-babyfood 0.100000 1.000 1.000 

14000040 14 Almond, oil 0.100000 1.000 1.000 

14000041 14 Almond, oil-babyfood 0.100000 1.000 1.000 

04010050 4A Amaranth, leafy 3.000000 1.000 1.000 

11000070 11 Apple, fruit with peel 1.000000 1.000 0.200 

11000080 11 Apple, peeled fruit 1.000000 1.000 0.200 

11000081 11 Apple, peeled fruit-babyfood 1.000000 1.000 0.200 

11000090 11 Apple, dried 1.000000 8.000 0.200 

11000091 11 Apple, dried-babyfood 1.000000 8.000 0.200 

11000100 11 Apple, juice 1.000000 1.300 0.200 

11000101 11 Apple, juice-babyfood 1.000000 1.300 0.200 

11000110 11 Apple, sauce 1.000000 1.000 0.200 

11000111 11 Apple, sauce-babyfood 1.000000 1.000 0.200 

12000120 12 Apricot 1.200000 1.000 1.000 

12000121 12 Apricot-babyfood 1.200000 1.000 1.000 

12000130 12 Apricot, dried 1.200000 6.000 1.000 

12000140 12 Apricot, juice 1.200000 1.000 1.000 

12000141 12 Apricot, juice-babyfood 1.200000 1.000 1.000 

01030150 1CD Arrowroot, flour 0.010000 1.000 1.000 

01030151 1CD Arrowroot, flour-babyfood 0.010000 1.000 1.000 

01030170 1CD Artichoke, Jerusalem 0.010000 1.000 1.000 

04010180 4A Arugula 3.000000 1.000 1.000 

09020210 9B Balsam pear 0.500000 1.000 1.000 

06020310 6B Bean, broad, succulent 0.400000 1.000 1.000 

06020330 6B Bean, cowpea, succulent 0.400000 1.000 1.000 

06020370 6B Bean, lima, succulent 0.400000 1.000 1.000 

06010430 6A Bean, snap, succulent 0.600000 1.000 1.000 

06010431 6A Bean, snap, succulent-babyfood 0.600000 1.000 1.000 

21000440 M Beef, meat 0.100000 1.000 1.000 

21000441 M Beef, meat-babyfood 0.100000 1.000 1.000 

21000450 M Beef, meat, dried 0.100000 1.920 1.000 

21000460 M Beef, meat byproducts 0.200000 1.000 1.000 

21000461 M Beef, meat byproducts-babyfood 0.200000 1.000 1.000 

21000470 M Beef, fat 0.100000 1.000 1.000 

21000471 M Beef,fat-babyfood 0.100000 1.000 1.000 

21000480 M Beef, kidney 0.200000 1.000 1.000 

21000490 M Beef, liver 0.200000 1.000 1.000 

21000491 M Beef, liver-babyfood 0.200000 1.000 1.000 

13010550 13A Blackberry 1.600000 1.000 1.000 

13010560 13A Blackberry, juice 1.600000 1.000 1.000 

13010561 13A Blackberry, juice-babyfood 1.600000 1.000 1.000 

13020570 13B Blueberry 1.600000 1.000 1.000 

13020571 13B Blueberry-babyfood 1.600000 1.000 1.000 

13010580 13A Boysenberry 1.600000 1.000 1.000 

14000590 14 Brazil nut 0.100000 1.000 1.000 

05010610 5A Broccoli 1.200000 1.000 0.050 

05010611 5A Broccoli-babyfood 1.200000 1.000 0.050 

05010620 5A Broccoli, Chinese 1.200000 1.000 1.000 

05020630 5B Broccoli raab 1.200000 1.000 1.000 

05010640 5A Brussels sprouts 1.200000 1.000 1.000 

14000680 14 Butternut 0.100000 1.000 1.000 
Acetamiprid Dietary Exposure and Risk Assessment DP No.: 372890

PC Code: 099050

Page 24 of 28

05010690 5A Cabbage 1.200000 1.000 0.050 

05020700 5B Cabbage, Chinese, bok choy 1.200000 1.000 1.000 

05010710 5A Cabbage, Chinese, napa 1.200000 1.000 1.000 

05010720 5A Cabbage, Chinese, mustard 1.200000 1.000 1.000 

09010750 9A Cantaloupe 0.500000 1.000 1.000 

04020760 4B Cardoon 3.000000 1.000 1.000 

09010800 9A Casaba 0.500000 1.000 1.000 

14000810 14 Cashew 0.100000 1.000 1.000 

01030820 1CD Cassava 0.010000 1.000 1.000 

01030821 1CD Cassava-babyfood 0.010000 1.000 1.000 

05010830 5A Cauliflower 1.200000 1.000 0.100 

04020850 4B Celery 3.000000 1.000 0.250 

04020851 4B Celery-babyfood 3.000000 1.000 0.250 

04020860 4B Celery, juice 3.000000 1.000 0.250 

04020870 4B Celtuce 3.000000 1.000 1.000 

09020880 9B Chayote, fruit 0.500000 1.000 1.000 

12000900 12 Cherry 1.200000 1.000 1.000 

12000901 12 Cherry-babyfood 1.200000 1.000 1.000 

12000910 12 Cherry, juice 1.200000 1.500 1.000 

12000911 12 Cherry, juice-babyfood 1.200000 1.500 1.000 

14000920 14 Chestnut 0.100000 1.000 1.000 

40000930 P Chicken, meat 0.010000 1.000 1.000 

40000931 P Chicken, meat-babyfood 0.010000 1.000 1.000 

40000940 P Chicken, liver 0.050000 1.000 1.000 

40000950 P Chicken, meat byproducts 0.050000 1.000 1.000 

40000951 P Chicken, meat byproducts-babyfoo 0.050000 1.000 1.000 

40000960 P Chicken, fat 0.010000 1.000 1.000 

40000961 P Chicken, fat-babyfood 0.010000 1.000 1.000 

40000970 P Chicken, skin 0.010000 1.000 1.000 

40000971 P Chicken, skin-babyfood 0.010000 1.000 1.000 

09021020 9B Chinese waxgourd 0.500000 1.000 1.000 

19011030 19A Chive 4.500000 1.000 1.000 

04011040 4A Chrysanthemum, garland 3.000000 1.000 1.000 

10001060 10 Citrus citron 0.500000 1.000 1.000 

10001070 10 Citrus hybrids 0.500000 1.000 1.000 

10001080 10 Citrus, oil 0.500000 1.000 1.000 

05021170 5B Collards 1.200000 1.000 1.000 

95001280 O Cottonseed, oil 0.600000 1.000 0.050 

95001281 O Cottonseed, oil-babyfood 0.600000 1.000 0.050 

11001290 11 Crabapple 1.000000 1.000 1.000 

95001300 O Cranberry 0.600000 1.000 1.000 

95001301 O Cranberry-babyfood 0.600000 1.000 1.000 

95001310 O Cranberry, dried 0.600000 1.000 1.000 

95001320 O Cranberry, juice 0.600000 1.100 1.000 

95001321 O Cranberry, juice-babyfood 0.600000 1.100 1.000 

04011330 4A Cress, garden 3.000000 1.000 1.000 

04011340 4A Cress, upland 3.000000 1.000 1.000 

09021350 9B Cucumber 0.500000 1.000 1.000 

13021360 13B Currant 1.600000 1.000 1.000 

13021370 13B Currant, dried 1.600000 1.000 1.000 

04011380 4A Dandelion, leaves 3.000000 1.000 1.000 

01031390 1CD Dasheen, corm 0.010000 1.000 1.000 

13011420 13A Dewberry 1.600000 1.000 1.000 

70001450 P Egg, whole 0.010000 1.000 1.000 

70001451 P Egg, whole-babyfood 0.010000 1.000 1.000 

70001460 P Egg, white 0.010000 1.000 1.000 

70001461 P Egg, white (solids)-babyfood 0.010000 1.000 1.000 

70001470 P Egg, yolk 0.010000 1.000 1.000 

70001471 P Egg, yolk-babyfood 0.010000 1.000 1.000 

08001480 8 Eggplant 0.200000 1.000 1.000 

13021490 13B Elderberry 1.600000 1.000 1.000 

04011500 4A Endive 3.000000 1.000 1.000 

04021520 4B Fennel, Florence 3.000000 1.000 1.000 

14001550 14 Filbert 0.100000 1.000 1.000 

14001560 14 Filbert, oil 0.100000 1.000 1.000 

03001640 3 Garlic 0.020000 1.000 1.000 

03001650 3 Garlic, dried 0.020000 1.000 1.000 

03001651 3 Garlic, dried-babyfood 0.020000 1.000 1.000 
Acetamiprid Dietary Exposure and Risk Assessment DP No.: 372890

PC Code: 099050

Page 25 of 28

01031660 1CD Ginger 0.010000 1.000 1.000 

01031661 1CD Ginger-babyfood 0.010000 1.000 1.000 

01031670 1CD Ginger, dried 0.010000 1.000 1.000 

23001690 M Goat, meat 0.100000 1.000 1.000 

23001700 M Goat, meat byproducts 0.200000 1.000 1.000 

23001710 M Goat, fat 0.100000 1.000 1.000 

23001720 M Goat, kidney 0.200000 1.000 1.000 

23001730 M Goat, liver 0.200000 1.000 1.000 

13021740 13B Gooseberry 1.600000 1.000 1.000 

95001750 O Grape 0.350000 1.000 1.000 

95001760 O Grape, juice 0.350000 1.000 1.000 

95001761 O Grape, juice-babyfood 0.350000 1.000 1.000 

95001770 O Grape, leaves 0.350000 1.000 1.000 

95001780 O Grape, raisin 0.350000 0.900 1.000 

95001790 O Grape, wine and sherry 0.350000 1.000 1.000 

10001800 10 Grapefruit 0.500000 1.000 0.025 

10001810 10 Grapefruit, juice 0.500000 2.100 0.025 

14001850 14 Hickory nut 0.100000 1.000 1.000 

09011870 9A Honeydew melon 0.500000 1.000 1.000 

24001890 M Horse, meat 0.100000 1.000 1.000 

13021910 13B Huckleberry 1.600000 1.000 1.000 

05021940 5B Kale 1.200000 1.000 1.000 

95001950 O Kiwifruit 0.350000 1.000 1.000 

05011960 5A Kohlrabi 1.200000 1.000 1.000 

10001970 10 Kumquat 0.500000 1.000 1.000 

10001990 10 Lemon 0.500000 1.000 0.050 

10002000 10 Lemon, juice 0.500000 2.000 0.050 

10002001 10 Lemon, juice-babyfood 0.500000 2.000 0.050 

10002010 10 Lemon, peel 0.500000 1.000 0.050 

04012040 4A Lettuce, head 3.000000 1.000 0.100 

04012050 4A Lettuce, leaf 3.000000 1.000 0.100 

10002060 10 Lime 0.500000 1.000 1.000 

10002070 10 Lime, juice 0.500000 2.000 1.000 

10002071 10 Lime, juice-babyfood 0.500000 2.000 1.000 

13012080 13A Loganberry 1.600000 1.000 1.000 

11002100 11 Loquat 1.000000 1.000 1.000 

14002130 14 Macadamia nut 0.100000 1.000 1.000 

28002210 M Meat, game 0.100000 1.000 1.000 

27002220 D Milk, fat 0.100000 1.000 1.000 

27002221 D Milk, fat - baby food/infant for 0.100000 1.000 1.000 

27012230 D Milk, nonfat solids 0.100000 1.000 1.000 

27012231 D Milk, nonfat solids-baby food/in 0.100000 1.000 1.000 

27022240 D Milk, water 0.100000 1.000 1.000 

27022241 D Milk, water-babyfood/infant form 0.100000 1.000 1.000 

27032251 D Milk, sugar (lactose)-baby food/ 0.100000 1.000 1.000 

05022290 5B Mustard greens 1.200000 1.000 1.000 

12002300 12 Nectarine 1.200000 1.000 1.000 

08002340 8 Okra 0.200000 1.000 1.000 

03002370 3 Onion, dry bulb 0.020000 1.000 1.000 

03002371 3 Onion, dry bulb-babyfood 0.020000 1.000 1.000 

03002380 3 Onion, dry bulb, dried 0.020000 9.000 1.000 

03002381 3 Onion, dry bulb, dried-babyfood 0.020000 9.000 1.000 

03002390 3 Onion, green 4.500000 1.000 1.000 

10002400 10 Orange 0.500000 1.000 0.025 

10002410 10 Orange, juice 0.500000 1.800 0.025 

10002411 10 Orange, juice-babyfood 0.500000 1.800 0.025 

10002420 10 Orange, peel 0.500000 1.000 0.025 

04012480 4A Parsley, leaves 3.000000 1.000 1.000 

06022550 6B Pea, succulent 0.400000 1.000 1.000 

06022551 6B Pea, succulent-babyfood 0.400000 1.000 1.000 

06012570 6A Pea, edible podded, succulent 0.600000 1.000 1.000 

06022590 6B Pea, pigeon, succulent 0.400000 1.000 1.000 

12002600 12 Peach 1.200000 1.000 0.010 

12002601 12 Peach-babyfood 1.200000 1.000 0.010 

12002610 12 Peach, dried 1.200000 7.000 0.010 

12002611 12 Peach, dried-babyfood 1.200000 7.000 0.010 

12002620 12 Peach, juice 1.200000 1.000 0.010 

12002621 12 Peach, juice-babyfood 1.200000 1.000 0.010 
Acetamiprid Dietary Exposure and Risk Assessment DP No.: 372890

PC Code: 099050

Page 26 of 28

11002660 11 Pear 1.000000 1.000 0.350 

11002661 11 Pear-babyfood 1.000000 1.000 0.350 

11002670 11 Pear, dried 1.000000 6.250 0.350 

11002680 11 Pear, juice 1.000000 1.000 0.350 

11002681 11 Pear, juice-babyfood 1.000000 1.000 0.350 

14002690 14 Pecan 0.100000 1.000 1.000 

08002700 8 Pepper, bell 0.200000 1.000 0.025 

08002701 8 Pepper, bell-babyfood 0.200000 1.000 0.025 

08002710 8 Pepper, bell, dried 0.200000 1.000 0.025 

08002711 8 Pepper, bell, dried-babyfood 0.200000 1.000 0.025 

08002720 8 Pepper, nonbell 0.200000 1.000 0.025 

08002721 8 Pepper, nonbell-babyfood 0.200000 1.000 0.025 

08002730 8 Pepper, nonbell, dried 0.200000 1.000 0.025 

14002820 14 Pistachio 0.100000 1.000 1.000 

12002850 12 Plum 1.200000 1.000 1.000 

12002851 12 Plum-babyfood 1.200000 1.000 1.000 

12002860 12 Plum, prune, fresh 0.200000 1.000 1.000 

12002861 12 Plum, prune, fresh-babyfood 0.200000 1.000 1.000 

12002870 12 Plum, prune, dried 0.400000 1.000 1.000 

12002871 12 Plum, prune, dried-babyfood 0.400000 1.000 1.000 

12002880 12 Plum, prune, juice 0.200000 1.400 1.000 

12002881 12 Plum, prune, juice-babyfood 0.200000 1.400 1.000 

25002900 M Pork, meat 0.100000 1.000 1.000 

25002901 M Pork, meat-babyfood 0.100000 1.000 1.000 

25002910 M Pork, skin 0.100000 1.000 1.000 

25002920 M Pork, meat byproducts 0.200000 1.000 1.000 

25002921 M Pork, meat byproducts-babyfood 0.200000 1.000 1.000 

25002930 M Pork, fat 0.100000 1.000 1.000 

25002931 M Pork, fat-babyfood 0.100000 1.000 1.000 

25002940 M Pork, kidney 0.200000 1.000 1.000 

25002950 M Pork, liver 0.200000 1.000 1.000 

01032960 1C Potato, chips 0.010000 1.000 0.025 

01032970 1C Potato, dry (granules/ flakes) 0.010000 6.500 0.025 

01032971 1C Potato, dry (granules/ flakes)-b 0.010000 6.500 0.025 

01032980 1C Potato, flour 0.010000 6.500 0.025 

01032981 1C Potato, flour-babyfood 0.010000 6.500 0.025 

01032990 1C Potato, tuber, w/peel 0.010000 1.000 0.025 

01032991 1C Potato, tuber, w/peel-babyfood 0.010000 1.000 0.025 

01033000 1C Potato, tuber, w/o peel 0.010000 1.000 0.025 

01033001 1C Potato, tuber, w/o peel-babyfood 0.010000 1.000 0.025 

60003010 P Poultry, other, meat 0.010000 1.000 1.000 

60003020 P Poultry, other, liver 0.050000 1.000 1.000 

60003030 P Poultry, other, meat byproducts 0.050000 1.000 1.000 

60003040 P Poultry, other, fat 0.010000 1.000 1.000 

60003050 P Poultry, other, skin 0.010000 1.000 1.000 

10003070 10 Pummelo 0.500000 1.000 1.000 

09023080 9B Pumpkin 0.500000 1.000 0.010 

09023090 9B Pumpkin, seed 0.500000 1.000 0.010 

11003100 11 Quince 1.000000 1.000 1.000 

29003120 M Rabbit, meat 0.100000 1.000 1.000 

04013130 4A Radicchio 3.000000 1.000 1.000 

05023180 5B Rape greens 1.200000 1.000 1.000 

20003190 20 Rapeseed, oil 0.010000 1.000 1.000 

20003191 20 Rapeseed, oil-babyfood 0.010000 1.000 1.000 

13013200 13A Raspberry 1.600000 1.000 1.000 

13013201 13A Raspberry-babyfood 1.600000 1.000 1.000 

13013210 13A Raspberry, juice 1.600000 1.000 1.000 

13013211 13A Raspberry, juice-babyfood 1.600000 1.000 1.000 

04023220 4B Rhubarb 3.000000 1.000 1.000 

03003380 3 Shallot 0.020000 1.000 1.000 

26003390 M Sheep, meat 0.100000 1.000 1.000 

26003391 M Sheep, meat-babyfood 0.100000 1.000 1.000 

26003400 M Sheep, meat byproducts 0.200000 1.000 1.000 

26003410 M Sheep, fat 0.100000 1.000 1.000 

26003411 M Sheep, fat-babyfood 0.100000 1.000 1.000 

26003420 M Sheep, kidney 0.200000 1.000 1.000 

26003430 M Sheep, liver 0.200000 1.000 1.000 

19023540 19B Spices, other 0.010000 1.000 1.000 
Acetamiprid Dietary Exposure and Risk Assessment DP No.: 372890

PC Code: 099050

Page 27 of 28

19023541 19B Spices, other-babyfood 0.010000 1.000 1.000 

04013550 4A Spinach 3.000000 1.000 0.050 

04013551 4A Spinach-babyfood 3.000000 1.000 0.050 

09023560 9B Squash, summer 0.500000 1.000 0.025 

09023561 9B Squash, summer-babyfood 0.500000 1.000 0.025 

09023570 9B Squash, winter 0.500000 1.000 0.025 

09023571 9B Squash, winter-babyfood 0.500000 1.000 0.025 

95003590 O Strawberry 0.600000 1.000 1.000 

95003591 O Strawberry-babyfood 0.600000 1.000 1.000 

95003600 O Strawberry, juice 0.600000 1.000 1.000 

95003601 O Strawberry, juice-babyfood 0.600000 1.000 1.000 

01033660 1CD Sweet potato 0.010000 1.000 1.000 

01033661 1CD Sweet potato-babyfood 0.010000 1.000 1.000 

04023670 4B Swiss chard 3.000000 1.000 1.000 

10003690 10 Tangerine 0.500000 1.000 1.000 

10003700 10 Tangerine, juice 0.500000 2.300 1.000 

01033710 1CD Tanier, corm 0.010000 1.000 1.000 

95003720 O Tea, dried 50.000000 1.000 1.000 

95003730 O Tea, instant 50.000000 1.000 1.000 

08003740 8 Tomatillo 0.200000 1.000 1.000 

08003750 8 Tomato 0.200000 1.000 1.000 

08003751 8 Tomato-babyfood 0.200000 1.000 1.000 

08003760 8 Tomato, paste 0.400000 1.000 1.000 

08003761 8 Tomato, paste-babyfood 0.400000 1.000 1.000 

08003770 8 Tomato, puree 0.200000 3.300 1.000 

08003771 8 Tomato, puree-babyfood 0.200000 3.300 1.000 

08003780 8 Tomato, dried 0.200000 14.300 1.000 

08003781 8 Tomato, dried-babyfood 0.200000 14.300 1.000 

08003790 8 Tomato, juice 0.200000 1.500 1.000 

50003820 P Turkey, meat 0.010000 1.000 1.000 

50003821 P Turkey, meat-babyfood 0.010000 1.000 1.000 

50003830 P Turkey, liver 0.050000 1.000 1.000 

50003831 P Turkey, liver-babyfood 0.050000 1.000 1.000 

50003840 P Turkey, meat byproducts 0.050000 1.000 1.000 

50003841 P Turkey, meat byproducts-babyfood 0.050000 1.000 1.000 

50003850 P Turkey, fat 0.010000 1.000 1.000 

50003851 P Turkey, fat-babyfood 0.010000 1.000 1.000 

50003860 P Turkey, skin 0.010000 1.000 1.000 

50003861 P Turkey, skin-babyfood 0.010000 1.000 1.000 

01033870 1CD Turmeric 0.010000 1.000 1.000 

05023890 5B Turnip, greens 1.200000 1.000 1.000 

14003910 14 Walnut 0.100000 1.000 1.000 

86010000 O Water, direct, all sources 0.005000 1.000 1.000 

86020000 O Water, indirect, all sources 0.005000 1.000 1.000 

09013990 9A Watermelon 0.500000 1.000 1.000 

09014000 9A Watermelon, juice 0.500000 1.000 1.000 

01034060 1CD Yam, true 0.010000 1.000 1.000 

01034070 1CD Yam bean 0.010000 1.000 1.000 

Attachment 6. Summary of DEEM-FCIDTM Chronic Results

U.S. Environmental Protection Agency Ver. 2.00

DEEM-FCID Chronic analysis for ACETAMIPRID (1994-98 data)

Residue file name: C:\Documents and Settings\dmcneill\My 

Documents\Actemidprid\PRIADNTacetamipridCT_chronic.R98

 Adjustment factor #2 used.

Analysis Date 01-12-2010/08:15:46 Residue file dated: 01-12-2010/08:15:02/8

Reference dose (RfD, Chronic) = .071 mg/kg bw/day

COMMENT 1: Acute/Chronic - UFs = 100

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 Total exposure by population subgroup

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 Total Exposure

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 Population mg/kg Percent of 

 Subgroup body wt/day Rfd 
Acetamiprid Dietary Exposure and Risk Assessment DP No.: 372890

PC Code: 099050

Page 28 of 28

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U.S. Population (total) 0.002835 4.0%

U.S. Population (spring season) 0.002861 4.0%

U.S. Population (summer season) 0.003114 4.4%

U.S. Population (autumn season) 0.002700 3.8%

U.S. Population (winter season) 0.002660 3.7%

Northeast region 0.002940 4.1%

Midwest region 0.002864 4.0%

Southern region 0.002639 3.7%

Western region 0.003022 4.3%

Hispanics 0.002916 4.1%

Non-hispanic whites 0.002817 4.0%

Non-hispanic blacks 0.002589 3.6%

Non-hisp/non-white/non-black 0.003635 5.1%

All infants (< 1 year) 0.005206 7.3%

Nursing infants 0.002502 3.5%

Non-nursing infants 0.006232 8.8%

Children 1-6 yrs 0.008045 11.3%

Children 7-12 yrs 0.003764 5.3%

Females 13-19 (not preg or nursing) 0.002017 2.8%

Females 20+ (not preg or nursing) 0.002107 3.0%

Females 13-50 yrs 0.002212 3.1%

Females 13+ (preg/not nursing) 0.002362 3.3%

Females 13+ (nursing) 0.002580 3.6%

Males 13-19 yrs 0.002313 3.3%

Males 20+ yrs 0.002013 2.8%

Seniors 55+ 0.002162 3.0%

Children 1-2 yrs 0.010358 14.6%

Children 3-5 yrs 0.007296 10.3%

Children 6-12 yrs 0.004055 5.7%

Youth 13-19 yrs 0.002170 3.1%

Adults 20-49 yrs 0.002031 2.9%

Adults 50+ yrs 0.002130 3.0%

Females 13-49 yrs 0.002057 2.9%

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