UNITED STATES ENVIRONMENTAL PROTECTION AGENCY WASHINGTON , D
.C

. 20460 

## MAR 31 2015

OFFICE OF CHEMICAL SAFETY AND POLLUTION PREVENTION MEMORANDUM
SUBJECT:
FROM:

THRU: BEAD Chemical Profile (BCP) for Registration Review: Bromuconazole (120503) Carl Chen, Plant Pathologist Biological Analysis Branch Rafael Prieto, Environmental Protection Specialist

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# P**,~"D** Science Information and Analysis Branch 

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# ""V II"''-" Stephen Smearman, Economist Economic Analysis Branch

# ~~ Biological and Economic Analysis Division (7503P) Arnet Jones, Chief Biological Analysis Branch Diann Sims, Chief

# ~ Science Information and Analysis Branch Timothy Kiely, Chief 

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### lA..-\_ Biological and Economic Analysi ivision (75 P TO: James Parker, Chemical Review Manager Risk Management and Implementation Branch 3 Pesticide Re-evaluatio, n Division (7508P) Office ofPesticide Programs (OPP)
Product Review Panel date: March 25, 2015

Page 1The Biological and Economic Analysis Division (BEAD) Chemical Profile (BCP) provides an overview ofthe pest management role and quantitative usage information available for a pesticide. Information provided in this BCP may be used by stakeholders (e.g., users and registrants), OPP risk and benefit assessors, OPP risk managers, and the general public during the Registration Reviewprocess ofbromuconazole. Bromuconazole was registered in the United States in2002. It is a fungicide registered under Section 3 ofthe Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) for use on roses in greenhouses. Ithas only one end-use product with an emulsifiable concentrate formulation containing 20% ofthe active ingredient bromuconazole. The fungicide is used as a foliar treatment applied in sufficient enough water to cover all above ground plant surfaces (EPA, 2015). Bromuconazole belongs to the triazole chemical group. It is a DMI (DeMethylation Inhibitor) fungicide classified bythe Fungicide Resistance Action Committee (FRAC) as a FRAC Group 3 fungicide. DMI fungicides are sterol biosynthesis inhibitors (SBI) but have no cross resistance to other SBI classes. In general, Group 3 fungicides have a mediumrisk ofresistance and the FRAC SBI Guidelines are available for resistance management (FRAC, 2014). Bromuconazole has a federal registration for prevention and control ofcertain diseases ofrose such as black spot (Diplocarpon rosaea). However, the California state registration information is not found inthe National Pesticide Information Retrieval System (NPIRS, 2015). The lack of a state registration could limit a pesticide's availability for use to control black spot onroses in greenhouses ifa state registration is required for its use in a state. There have been no BEAD benefits assessments or FIFRA Section 18 emergency exemption requests for bromuconazole in the last 10 years. While an emergency exemptionrequest may yield information about a chemical's importance or value that is not found in other EPA records, the lack ofa FIFRA Section 18 assessment by BEAD does not specifically indicate the relative importance ofthis chemical. Quantitative usage information for bromuconazole is not available. Obtaining the following infonnation may improve future assessments related to the use and importance of bromuconazole: 1) total pounds ofactive ingredient applied per year on a national and/or regional basis; 2) percent crop/site treated; 3) application rates: typical and maximum; 4) frequency and intervals ofapplication; and 5) efficacy infonnation/product perfonnance. REFERENCES EPA. 2015. EPA-approved bromuconazole technical and end-use labels. Accessed March 2015 at http://ofmpub.epa
.gov/apex/pesticides/f?p=PPLS: 1
. FRAC. 2014. Fungicide Resistance Action Committee (FRAC)- 2014 FRAC Code List©. Accessed March 2015 at http://www.frac.info/frac/publication/anhang/2014%20FRAC%20Code%20List.pdf
. NPIRS. 2015. Bromuconazole federal/state registrations. National Pesticide Infonnation Retrieval System (NRIRS). Accessed March 2015 at http://npirs.ceris.purdue.edu
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