Powdered Corn Cobs (Cellulose) DP Number: 402046, 402312

PC Code: 100154 EPA File Symbol No.: 84889
- E Ty pe of Review: Product Chemistry , Toxicology 

### 1

OFFICE OF CHEMICAL SAFETY AND POLLUTION PREVENTION **UNITED ST AT**  **ES ENVIRONMENT AL**  **PROTECTION A GENCY** 

WA SHINGTON, D.C. 20460


### MEMORANDUM **DATE:** October 3 , 2012 **SUBJECT** : Science Review in Suppo rt of Rode
- Trol , Containing 90.0% Powdered Corn Cobs

( 33.3 % Cellulose) As Its Active Ingredient. **Decision Number:** 447148 **DP Number:** 402046, 402312 **EPA File Symbol Number:** 84889
- E **Chemical Class:** B iochemical **PC Code:** 100154 **CAS Number:** 9004
- 34
- 6 (cellulose) **Active Ingredient Tolerance Exe**  **mptions:** Nonfood
- use **MRID Numbers** 

### : 48433501
- 4843350 3 

### , 48433506, 48533801
- 48533802 , 48824701*not all MRIDs are associated with the DP numbers. 

### FROM: Angela L. Gonzales, Biologist

Biochemical Pesticides Branch Biopesticides & Pollution Prevention Division (7511P ) **TO :**  Leonard Cole, Senior Regulatory Specialist Biochemical Pesticides Branch Biopesticides & Pollution Prevention Division (7511P ) **ACTION REQUESTED** On behalf of Rode
- Trol, LLC, E x

### ponent, Inc. requests registration of Rode
- Trol , an end
- use product (E P) containing powdered corn cobs (33.3 % cellulose)
. The chemical is a new biochemical active ingredient
. The proposed E P is intended for use as a rodenticide in commercial and residential indoor sett ings. In support of the proposed E P, the registrant submitted a proposed product label, Confidential Statement of Formula s (CSF s) dated 7/12/11 , product chemistry data and information in MRIDs 484335 01
- 4843340 2, 48533801 and 48824701 and mammalian toxicology data and information in MRIDs 48433503, 48433506 and 48533802
. **RECOMMENDATIONS AND CONCLUSION**

### 1. The product chemistry submission is **ACCEPTABLE pending resolution of the deficiencies** 

**discussed below. MRID**  **484335 0**  **1 -**  **UPGRADEABLE MRID 48**  **4335 02**  **- UPGRADEABLE**  **MRID 48 533801**  **- ACCEPTABLE**  **MRID 48824701 -**  **ACCEPTABLE** 

### a. Refer to the Confidential Appendix (CA) below. b. Refer to the CA below. c. The active ingredient statement on the label must be revised as follows: **ACTIVE INGREDIENT:** Powdered Corn Cobs*...............................90% **OTHER INGREDIENT(S):**
...................... 10% TOTAL : 100% *Contains 33.3% w/w Cellulose d. Refer to the CA below.
e . The bulk density of the MP was provided to fulfill the density data requirement for the EP
. Density data for the EP should be provided and listed in box 7 on the CSF. f . The rationale provided to satisfy the storage stability

(OCSPP 830.6317) and corrosion characteristics (OCSPP 830.6320) is inadequate. Additional scientifically
- sound rationale supported by references must be submitted or studies must be conducted. **2. The mammalian toxicology submission is ACCEPTABLE.**  **MRID 4843350 3**  **- UPGRADEABLE**  **MRID 484335 06**  **- ACCEPTABLE**  **MRID 48 533802**  **- ACCEPTABLE**  

### 3. Nontarget toxicology data are not required for the EP at this time. NOTE TO RAL: 1. Inthe “Ingredients” row on the data matrix dated 7/12/11, the applicant listed the active ingredient as mono - and di
- potassium salts of phosphorous acid which must be revised. 2. Efficacy

data were submitted to support registration of the EP but were re viewed b y another science reviewer. Refer to the memoranda from C. Fuentes for more information.

**STUDY SUMMARIES Product Chemistry (MRIDs 48433501**  **- 48433502, 48533801**  **and 48824701 )** Powdered Corn Cobs (Cellulose) DP Number: 402046, 402312

PC Code: 100154 EPA File Symbol No.: 84889
- E Ty pe of Review: Product C hemistry, Toxicology 

### 3
All data requirements have been satisfied with the exception of storage stability and corrosion characteristics. Physical and chemical properties data for the EP are summarized in Table 1 below. Data Evaluation Records (DERs) were not created for the submitted MRIDs
. Refer to the CA below for more product chemistry information
. **TABLE 1 . Physical and Chemical Properties of**  **Rode -**  **Trol (40 CFR § 158.2030)**  **OCSPP Guideline**  **Property Description of Result**  **(PC 38 -**  **DD) MRID**  830.6302 Color Light
- brown/beige 48433502 830.6303 Phy sical State Solid pellet 48433502 830.6304 Odor Characteristic of hay 48433502 830.6313 Stability to Normal and

E levated Tem

peratures, Metals and Metal I ons Not required for EP 830.6315 Flammability Flash point: 388oF (open cup); 396 oF (closed cup) (data are bridged from TGAI; inert components not expected to contribute significantly to flammability) 48433502
830.6317 Storage Stability **Rationale is inadequate** 48433502 830.6319 Miscibility N/A: not an emulsifiable liquid that will be diluted with petroleum solvents. 48433502 830.6320 Corrosion Characteristics **Rationale is inadequate** 48433502 830.7000 pH N/A: test substance is not soluble or dispersible in water 48433502 830.7050 UV/Visible Light

Absorption Not required for EP 830.7100 Viscosity N/A: product is a solid 48433502 830.7200 Melting Point/Range Not required for EP 830.7220 Boiling Point/Range Not required for EP 830.7300 Bulk Density **28.0 lb/ft 3**  **(data are for the MP and should be sub**  **mitted for the EP)** 48433502 830.7520 Particle Size, Fiber Length and

Diameter Distribution Not required for EP 830.7550 830.7560 830.7570 Partition Coefficient (n
Octanol/Water) Not required for EP 830.7840 Water Solubility Not required for EP 830.7950 Vapor Pressure Not required for EP 

### Mammalian Toxicology (MRIDs **48433503, 48433506 and 48533802)**