Exhibit






FOURTH AMENDMENT TO LEASE DATED JUNE 29, 2018


Nancy Ridge Technology Center, L.P., a California limited partnership (“Lessor”), and Cidara Therapeutics, Inc., a Delaware corporation, (“Lessee”), hereby amend the Lease dated June 9, 2014 (as previously amended, the “Lease”), for Suites #101 through #105 at 6310 Nancy Ridge Drive, San Diego, CA 92121 (“Premises”) as follows:


		
	1)
	Expiration Date:  The Lease Term is hereby extended and the Expiration Date shall be December 31, 2021.  Lessee continues to have the right to exercise the options to extend the term of the Lease pursuant to the terms and conditions of Paragraph 57 of the addendum to the Lease.




		
	2)
	Increase in Base Rent:  On January 1, 2019 the Base Rent shall increase to $69,649.30 per month.  On January 1, 2020, and every twelve (12) months thereafter, the Base Rent shall increase three percent (3%).




		
	3)
	HVAC:  Provided (a) Lessee has not modified the HVAC system, (b) Lessee has properly maintained the HVAC system, and (c) Lessor has reasonably approved the repair in advance of such repair being done, then, for each repair or replacement of a HVAC unit that is over twelve (12) years old, Lessee shall be responsible for the first $500 of the required repair or replacement, and Lessor shall be responsible any amount over $500 until after the HVAC unit is replaced with a new HVAC unit, at which time Lessee shall be responsible for all repair and replacement costs for the new HVAC unit.  Notwithstanding the foregoing, Lessor shall continue to have the obligation to replace, when needed and without any reimbursement from Lessee, the HVAC units described in Paragraph 4 of the Third Amendment to Lease.  A schedule of the HVAC units is attached as Exhibit A hereto.  Except as provided in this paragraph, Lessor's and Lessee's obligations with respect to maintenance, repair, and replacement of HVAC units that service the Premises remain unchanged, including, (1) all maintenance costs for all HVAC units shall remain Lessee’s sole responsibility and (2) Lessor's and Lessee's obligations described in Paragraph 4 of the Third Amendment to Lease are not amended by this paragraph.




		
	4)
	Tenant Improvements:  Lessor waives any restoration rights as to tenant improvements approved by Lessor prior to the date of this Amendment, and specifically Lessee shall not be required to restore the offices removed at the rear of Suite #103 to create rooms #307, #309, #310 and #316.




		
	5)
	Option to Expand: Provided Lessee has not Defaulted (whether subsequently cured or not) under any of the terms of the Lease, then, subject to any existing rights of any other tenants of the Project, Lessee shall have the option to lease any vacant space controlled by Lessor in 6310 or 6330 Nancy Ridge Drive in its as-is condition without warranty at the same terms and conditions in the Lease (as amended by this Amendment), including the same rate of Base Rent/sf, Base Rent increases, and Expiration Date; however, Lessee's Share shall be increased based upon the added area of the Expansion Space (defined below).  To exercise the option, Lessee must, on or before September 30, 2019, deliver to Lessor written notice that states (1) Lessee is exercising the option, (2) the vacant space that Lessee desires to lease, which space must be (i) one or more full suites and (ii) fully demised from other spaces in the building (such space described in the notice is herein referred to as "the Expansion Space"), and (3) the date Lessee wants to take possession of the Expansion Space, which date shall not be later than 15 days after 











the date of Lessee's notice.  All provisions of the Lease, including Lessee's obligation to pay Rent, shall apply to the Expansion Space commencing on the earlier of (1) the date Lessee takes possession of the Expansion Space or (2) the date specified in Lessee's notice.  Lessee's option under this paragraph shall not apply to any vacant space with respect to which Lessor has received an acceptable letter of intent to lease prior to the date Lessee delivers Lessee's notice exercising Lessee's option.


		
	6)
	Special Option re 6330 Nancy Ridge Drive, Suite 104.  This paragraph is agreed to by Lessor and Lessee with reference to the following facts:  (1) the premises commonly known as 6330 Nancy Ridge Drive, Suite 104 (the "IVS Space") is currently occupied by IVS Technologies, Inc., pursuant to a lease (the "IVS Lease") between Lessor and IVS Technologies, Inc., (2) IVS is actively attempting to sublease the IVS Space, and (3) Lessee may desire to sublease the IVS Space for the remaining term of the IVS Lease, provided that Lessor agrees to a direct lease with Lessee for the IVS Space for the period commencing on the expiration date of the IVS Lease and ending on the Expiration Date of the Lease.  Based upon such facts, Lessor and Lessee agree, if prior to July 31, 2018 ("the Special Option Expiration Date"), Lessee and IVS Technologies, Inc. enter into a sublease for the IVS Space, then (1) Lessor shall not unreasonably withhold Lessor's consent to such sublease and (2) Lessee shall have the option to lease the IVS Space in its as-is condition without warranty at the same terms and conditions in the Lease (as amended by this Amendment), including the same rate of Base Rent/sf, Base Rent increases, and Expiration Date; however, (1) the terms of the Lease, including the obligation to pay Rent, shall apply to the IVS Space commencing upon expiration or earlier termination the IVS Lease and (2) Lessee's Share shall be increased based upon the added area of the IVS Space.  To exercise the option, Lessee must, on or before July 31, 2018, (1) enter into a sublease with IVS Technologies, Inc. pertaining to the IVS Space, (2) have received Lessor's consent to such sublease, and (3) deliver to Lessor written notice that states Lessee is exercising the option.  Lessor agrees that, if prior to the Special Option Expiration Date Lessor receives from IVS Technologies, Inc., a written request for Lessor to consent to a sublease of the IVS Space with anyone other than Lessee, Lessor shall promptly after receiving such request advise Lessee that Lessor has received such request; however, Lessor shall not be obligated to provide to Lessee any information concerning the terms and conditions of such proposed sublease.




		
	7)
	Confidentiality: The terms of the Lease are confidential.  No party to the Lease shall disclose any of the terms of the Lease to any other party, provided that Lessee may disclose such terms to Lessee's employees, directors, officers, agents and proposed transferees.




		
	8)
	No Default: To each party's knowledge, neither party is currently in Default or Breach of any of the terms or conditions of the Lease.




		
	9)
	Authority to Execute: Each person executing this Amendment represents and warrants to all parties that he or she is duly authorized to execute and deliver this Amendment on behalf of that party.




All other terms and conditions of the Lease shall remain in full force and effect.  All capitalized terms used herein but not defined herein shall have the meanings ascribed thereto in the Lease.













		
	Lessor:
	Nancy Ridge Technology Center, L.P., a California Limited Partnership


		
	By:
	Nancy Ridge Technology Center, LLC, a California Limited Liability Company, 


its General Partner


By:                                
Chris Loughridge, its Manager    




Lessee:        Cidara Therapeutics, Inc., a Delaware corporation 


By:                                


Printed:    Matthew Onaitis


Title:    CFO & General Counsel











Schedule of Exhibits


Exhibit A--Schedule of HVAC Units









Exhibit A--HVAC SCHEDULE
	
							
	HVAC UNITS  (3/28/18)

	 
	 
	 
	 
	 
	 
	 

	HVAC COVERED BY LEASE

	Unit number
	# on unit
	model number
	serial number
	manufacturer
	year of man.
	age

	 
	 
	 
	 
	 
	 
	 

	101-1
	101-1
	50EZ-A24-30
	2614C13907
	Carrier
	2014
	4 years

	101-2
	101-2
	RQPL-B042CK  000
	F231700029
	Rheem
	2017
	1 year

	101-3
	101-3
	50TCQD12A2A5A0A0A0A0
	3812G50170
	Carrier
	2012
	6 years

	101-4
	101-4
	50EZ-A48-50
	2814C41445
	Carrier
	2014
	4 years

	101-5
	101-5
	unknown
	unknown
	Carrier
	1987
	31 years

	101-6
	101-6
	50TCQDU8A2A5A0A0A0
	2616P97919
	Carrier
	2016
	2 years

	101-7
	101-7
	50TJQ009-501
	4498G30498
	Carrier
	1998
	20 years

	102-1
	102-1
	50TCQD09A2A5A0A0A0
	0716P60797
	Carrier
	2016
	2 years

	102-2
	102-2
	YHJD60S43S5A
	W1K4091677
	York
	2014
	4 years

	102-3
	102-3
	B1HA024A06B
	(s) NHHM110673
	York
	1999
	19 years

	102-4
	102-4
	B3CH060A25ECC
	(s) NMHM159010
	York
	1999
	19 years

	102-5
	102-5
	B3CH120A25ECB
	(s) NLHM144215
	York
	1999
	19 years

	102-6
	102-6
	B3CH090A25ECB
	(s) NMHM161575
	York
	1999
	19 years

	103 new
	103-3
	50VT-B24-30TP
	2715C12842
	Carrier
	2015
	3 years

	103-4
	103-4
	50EZ-A24-30
	4311C15143
	Carrier
	2011
	7 years

	103-5
	103-5
	50TCQA04A2A5A0A0A0
	4111C59853
	Carrier
	2011
	7 years

	103-6
	103-6
	50TCQA05A2A5A0A0A0
	3511C57334
	Carrier
	2011
	7 years

	103-7
	103-7
	WCC024F100BB
	L393RY42H
	Trane
	1996
	22 years

	103-8
	103-8
	out of service
	 
	 
	 
	 

	old
	103-9
	WCG036F100BB
	391PLWH
	Trane
	1999
	19 years

	old
	103-10
	WCC024F100BB
	3925BM2H
	Trane
	1996
	22 years

	104-1
	104-1
	CPH060XXX3BXXXBA
	1007418928
	Goodman
	2010
	8 years

	104-2
	104-2
	CPH060XXX3BXXXBA
	1007418931
	Goodman
	2010
	8 years

	104-3
	104-3
	RQKA-A030JK 000
	5616F519712489
	Rheem
	1997
	21 years

	105-11
	105-11
	50TCQA04A2A5A0A0A0
	0415C55917
	Carrier
	2015
	3 years

	105-12
	105-12
	38AYC048320
	1700E00271
	Carrier
	2000
	8 years

	105-13
	105-13
	RQKA-A030JK 000
	6516F429706089
	Rheem
	1997
	21 years

	105-14
	105-14
	48GS-060090501
	0700G10083
	Carrier
	2000
	8 years

	105-5
	105-15
	48TCDD12AZA5A0A0A0
	1115P62329
	Carrier
	2015
	3 years

	105-6
	105-16
	48TCDD12A2A5A0A0A0
	1615P42764
	Carrier
	2015
	3 years

	 
	 
	 
	 
	 
	 
	 

	HVAC 6330 NRD

	suite 104 1st. Fl
	AC-3
	 
	3311C56083
	Carrier
	2011
	7 years

	suite 104 1st. Fl
	AC-4
	 
	1012C66081
	Carrier
	2012
	6 years

	suite 104 1st. Fl
	AC-5
	 
	1212C85580
	Carrier
	2012
	6 years