1

Prometon Focus Meeting Summary

November 7, 2012 

1:00 – 2:00 pm

Attendees

MANA: Kristen Knox and (via conference line) Elliot Gordon

Control Solutions, Inc.(via conference line): Anne Turnbough

Environmental Protection Agency (EPA or Agency): Kaitlin Keller (PRD), Tracy Perry 

(PRD), William Irwin (HED), Robin Sternberg (EFED), Steve Wente (EFED), Sujatha Sankula 

(EFED), Cynthia Doucoure (BEAD), John Faulkner (BEAD)

Objective

The purpose of the meeting was for members of the EPA’s Pesticide Re-evaluation Division 

(PRD), Environmental Fate and Effects Division (EFED), Biological and Economic Analysis 

Division (BEAD), and Health Effects Division (HED) to meet with Mahkteshim Agan of North 

America (MANA), the technical registrant for prometon, for the following reasons: 1) discuss 

usage information needed for the registration review ecological risk assessments, and 2) discuss 

anticipated ecotoxicity and environmental fate data requirements and information that could be 

submitted to fulfill these data gaps. 

Discussion

Use/Usage Information

CSI provided usage information in terms of amounts used in pounds per year, noting that this 

information can be broken down by product and will be submitted to the Agency with a complete 

summary of labels and use sites. MANA confirmed that all residential use products have been 

cancelled, as required by the Reregistration Eligibility Decision (RED). EPA has also received a 

FIFRA 6(f) request from MANA, dated October 4, 2012, to cancel all residential uses of 

prometon on October 3, 2012, which will be published with a 30-day comment period in the 

Federal Register in December 2012. EPA requested additional information on typical rates for 

each use scenario and the size of a typical spot treatment for various use sites, such as highway 

medians, fencerows, and airports. EPA noted that this information could help reduce 

conservative assumptions in the ecological risk assessments. 

Environmental Fate and Effects Information

EPA requested additional information on the degradates of prometon, specifically how long they 

take to break down and any toxicity effects in the environment and/or any laboratory toxicity 

studies. MANA committed to reviewing their database and providing any available information.

EPA also discussed a list of anticipated data gaps and explained some of the conservative 

methods, such as the acute-to-chronic ratio, that would be used if no additional data were 

submitted. MANA stated that European Union (EU) data is not available for this chemical and 

all available studies have already been submitted for the RED assessment. EPA suggested 
2

reviewing open literature and MANA’s database for information on other triazine herbicides, 

such as atrazine and simazine, for information which may be useful. EPA agreed to review any 

proposals or waiver requests based on a rationale of low toxicity and/or bridging data used for 

other triazine class herbicides. EPA requested any water monitoring data available. MANA was 

not aware of this information but agreed to submit any water monitoring data that they may find.

Follow-up

• EPA will inform MANA when the 6(f) voluntary cancellation request for all prometon 

residential uses publishes in the Federal Register.

• MANA and CSI will submit use/usage and market share information, as well as typical 

use rates and size of typical spot treatments.

• MANA will review their scientific database and open literature sources for information 

that could fulfill current data gaps and respond to EPA with this information within three 

weeks.