**Exhibit      31.1**

**Certification      Under Section 302**

|   |                      a) designed such disclosure controls and procedures, or caused such                disclosure controls and procedures to be designed under our supervision,                to ensure that material information relating to the registrant, including                its consolidated subsidiaries, is made known to us by others within                those                entities, particularly during the period in which this report is                being                prepared;    |
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|   |                      b) omitted paragraph pursuant to SEC Release Nos. 33-8238 and                34-47986;                                                                                                                                                                                                                                                                                                                                                                                                        |
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|   |                      c) evaluated the effectiveness of the registrant’s disclosure                controls and procedures and presented in this report our conclusions                about                the effectiveness of the disclosure controls and procedures, as of                the end                of the period covered by this report based on such                evaluation; and                                                                                                   |
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|   |                      d) disclosed in this report any change in the registrant’s internal                control over financial reporting that occurred during the registrant’s                most recent fiscal quarter (the registrant’s fourth fiscal quarter in the                case of an annual report) that has materially affected, or is reasonably                likely to materially affect, the registrant’s internal control over                financial reporting; and |

|   | a)                all significant deficiencies and material weakness in the design                or                operation of internal controls over financial reporting which are                reasonably likely to adversely affect the registrant’s ability to record,                process, summarize and report financial information;                and |
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|   | b)                any fraud, whether or not material, that involves management or other                employees who have a significant role in the registrant’s internal                controls over financial reporting. |
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| Date:                November 14, 2006  |   |   |   | By: |   | /s/                Noah                Berkowitz, M.D., Ph.D.  |
|                                         |   |   |   |   |   | Noah                Berkowitz, M.D., Ph.D.President                and Chief Executive Officer(principal                executive                officer) |