United States Department of Agriculture

Agricultural Marketing Service, Science & Technology

Pesticide Data Program

SOP No.: PDP-QC Page 1 of 47

Title: Chemical Compounds, PDP Commodity Grouping, Method Validation and Quality Control

Revision: 12 Replaces: 09/01/2021 Effective: 06/01/2023

1. Purpose:

To provide a reference of PDP required compounds, a listing of available marker pesticides and 

process controls, specification of PDP commodity groupings, requirements for method validation 

and continuing quality control (QC) for Monitoring Programs Division (MPD) Pesticide Data 

Program (PDP) samples.

2. Scope:

This standard operating procedure (SOP) shall be followed by all analytical laboratories conducting 

pesticide residue studies for PDP, including support laboratories conducting stability or other types 

of studies that may impact the program. 

3. Outline of Procedure:

5. Specific Procedures

5.1 Required Compounds 

5.2 Standards 

5.3 Method Validation Background 

5.4 General Method Validation Requirements 

5.5 Method Validation Evaluation Guidelines 

5.6 Method Validation Scenarios 

5.7 Marker Pesticides 

5.8 Process Control Compounds 

5.9 PDP Commodity Groupings 

5.10 Establishment of LODs and LOQs 

5.11 Verification of LODs/LOQs 

5.12 Changing LODs 

5.13 Determination of Method Range 

5.14 Precision and Accuracy Data Collection 

5.15 Method Evaluation Reporting 

5.16 Method Validation Evaluation by MPD 

5.17 Blanks and Spikes Required Per Set and Continuing QC 

5.18 Criteria for Method Validation and Continuing QC 

5.19 Proficiency Testing 

5.20 Measurement Uncertainty 
United States Department of Agriculture

Agricultural Marketing Service, Science & Technology

Pesticide Data Program

SOP No.: PDP-QC Page 2 of 47

Title: Chemical Compounds, PDP Commodity Grouping, Method Validation and Quality Control

Revision: 12 Replaces: 09/01/2021 Effective: 06/01/2023

Attachment 1. Method Evaluation Flowchart

Attachment 2. PDP Compound Groups, Pesticide Codes and Multi-residue Compound 

Groupings for Fruit and Vegetables

Attachment 3. EPA, Codex, and Food and Drug Administration (FDA) Pesticide Analytical 

Manual (PAM) Commodity Groupings

Attachment 4. FDA Information for percent fat, water, sugar and pH content for Commodity 

Groupings

Attachment 5. Method Evaluation Reporting Forms [LOD Verification, Determination of 

Method Range, Precision and Accuracy Data Collection]

Attachment 6. Process Control and Spike Recovery Acceptability Flowchart

4. References:

• Association of Official Analytical Chemists (AOAC), Quality Assurance Principles for 

Analytical Laboratories, 1991, pp. 91-94

• Avramides, The Stability of Pure Standards and Stock Standard Solutions for Pesticide Residue 

Determination Using Gas Chromatography, 5th European Pesticide Residue Workshop, 

Stockholm, Sweden, June 13-16, 2004

• Codex Alimentarius Commission, Codex Pesticides Residues in Food Online Database, 

http://www.fao.org/fao-who-codexalimentarius/codex-texts/dbs/pestres/en/

• De Kok et. al., The Stability of Pesticide Standards and Solutions, 5th European Pesticide 

Residue Workshop, Stockholm, Sweden, June 13-16, 2004

• Federal Register, Rules and Regulations, Volume 49, Number 209, October 26, 1984, 

https://www.govinfo.gov/app/details/FR-1984-10-26

• Garfield, F., Quality Assurance Principles for Analytical Laboratories, AOAC, 1991

• Horwitz, W., Evaluation of Analytical Methods Used for Regulation of Foods and Drugs, 

Analytical Chemistry, Vol. 54, No. 1, pp. 67A-76A, 1982, 

https://pubs.acs.org/toc/ancham/54/1#

• National Environmental Laboratory Accreditation Conference (NELAC), Standards, Appendix 

D, Section D.1.1.2.1, Laboratory Control Samples (LCS), June 5, 2003, https://nelacinstitute.org/docs/2003nelacstandard.pdf

• Taylor, J.T., Quality Assurance of Chemical Measurements, Lewis Publishers, 1989
United States Department of Agriculture

Agricultural Marketing Service, Science & Technology

Pesticide Data Program

SOP No.: PDP-QC Page 3 of 47

Title: Chemical Compounds, PDP Commodity Grouping, Method Validation and Quality Control

Revision: 12 Replaces: 09/01/2021 Effective: 06/01/2023

U.S. Environmental Protection Agency (EPA), Facilities for Handling Test, Control, and 

Reference Substances, 40 CFR 160.47, https://www.ecfr.gov/cgi-bin/textidx?SID=2b73966e9fe66d367433350be5f9cf87&mc=true&node=se40.26.160_147&rgn=div8

• U.S. EPA, Mixtures of substances with carriers, 40 CFR 160.113, https://www.ecfr.gov/cgibin/textidx?SID=46e8ce3ae343b54c18065bd0f61a366c&mc=true&node=se40.26.160_1113&rgn=div

8

• U.S. EPA, Pesticide Use Index - Index of pesticide use sites: Corresponding Major Use 

Pattern(s) and Crop Group, 

https://www.epa.gov/sites/production/files/2014-06/documents/terrestrial-food.pdf

• U.S. EPA, Reagents and Solutions, 40 CFR 160.83, https://www.ecfr.gov/cgi-bin/textidx?SID=46e8ce3ae343b54c18065bd0f61a366c&mc=true&node=se40.26.160_183&rgn=div8

• U.S. EPA, Standard Operating Procedures, 40 CFR part 160.81, https://www.ecfr.gov/cgibin/textidx?SID=46e8ce3ae343b54c18065bd0f61a366c&mc=true&node=se40.26.160_181&rgn=div8

• U.S. EPA, Test, Control, and Reference Substance Characterization, 40 CFR 160.105, 

https://www.ecfr.gov/cgi-bin/textidx?SID=46e8ce3ae343b54c18065bd0f61a366c&mc=true&node=se40.26.160_1105&rgn=div

8

• U.S. EPA, Test, Control, and Reference Substance Handling, 40 CFR 160.107, 

https://www.ecfr.gov/cgi-bin/textidx?SID=46e8ce3ae343b54c18065bd0f61a366c&mc=true&node=se40.26.160_1107&rgn=div

8

• U.S. FDA, Approximate pH of Foods and Food Products,

http://www.webpal.org/SAFE/aaarecovery/2_food_storage/Processing/lacf-phs.htm

• U.S. FDA, Pesticide Analytical Manual Volume I (PAM) 3rd Edition, Chapter 2,

 https://www.fda.gov/media/74477/download

• U.S. FDA, Standard Operating Procedures for the Total Diet Study, KCM TD G2, revision 0,

Quality Assurance, January 1993

• Vieth et. al, Storage Stability of Stock Solutions and Solid Pesticide Standards, 5th European 

Pesticide Residue Workshop, Stockholm, Sweden, June 13-16, 2004

Note: References consulted in the preparation of this SOP document.
United States Department of Agriculture

Agricultural Marketing Service, Science & Technology

Pesticide Data Program

SOP No.: PDP-QC Page 4 of 47

Title: Chemical Compounds, PDP Commodity Grouping, Method Validation and Quality Control

Revision: 12 Replaces: 09/01/2021 Effective: 06/01/2023

5. Specific Procedures:

This SOP represents minimum PDP requirements and is presented as a general guideline. Each 

laboratory shall have written procedures that provide specific details concerning how the procedure 

has been implemented in that laboratory.

5.1 Required Compounds

5.1.1 Refer to applicable commodity/compound-specific memorandum for commodity 

specific testing profiles.

5.1.2 Priority Levels

5.1.2.1 Each analyte of interest for each assigned commodity shall be designated with a 

priority level by the MPD. Priority levels for the individual compounds in the commodityspecific memorandum distributed to the analyzing laboratories are based on data needs 

identified by data users/stakeholders (e.g., U.S. Environmental Protection Agency (EPA), 

U.S. Food and Drug Administration (FDA), grower groups, industry, 

consumer/environmental groups), current tolerances and Action Levels (ALs), and 

national/international Maximum Residue Levels (MRLs). In addition, compounds that may 

not have tolerances in the U.S., but are known to be used in countries that export food to the 

U.S. are included; these compounds are comprised of compounds identified by EPA as 

having a high probability of consumption in selected imported products, and analytes 

identified by FDA or USDA Foreign Agricultural Service (FAS) as of interest in selected 

imported products, where applicable to a given commodity. It is recognized that not all 

compounds/metabolites on a given list are amenable to multiresidue testing and final 

screening lists will be determined based on method validation and ongoing testing results.

5.1.2.2 In the various commodity-specific memoranda (separate documents distributed 

to analyzing laboratories), compounds identified as Priority 1 compounds are the most 

critical and those identified as Priority 3 are the least critical. The priority level is a 

combination of data needs and expected feasibility of current methods to recover a given 

compound. General priority levels are assigned according to the following protocol:

5.1.2.2.1 Priority 1 compounds are selected multiresidue-amenable pyrethroids, 

organophosphates, and carbamates and their associated metabolites, as well as specific 
United States Department of Agriculture

Agricultural Marketing Service, Science & Technology

Pesticide Data Program

SOP No.: PDP-QC Page 5 of 47

Title: Chemical Compounds, PDP Commodity Grouping, Method Validation and Quality Control

Revision: 12 Replaces: 09/01/2021 Effective: 06/01/2023

compounds identified as high priority by data users/stakeholders. Priority 1 compounds 

are required for all commodities. 

5.1.2.2.2 Priority 2 compounds include other analytes with tolerances (including food 

handling establishment tolerances) or ALs (e.g., environmental contaminants/extraneous 

residues – aldrin, BHC, chlordane, chlordecone, DDD, DDE, DDT, dicofol, dieldrin, 

ethylene dibromide, heptachlor, heptachlor epoxide, lindane, and mirex) for the given 

commodity and are routinely analyzed by multiresidue methods. Priority 2 compounds 

may also include chemicals used in other countries, dependent upon their anticipated 

method behavior. Priority 2 may also include specific compounds identified by data 

users/stakeholders.

5.1.2.2.3 Priority 3 compounds include pesticides that have current tolerances, but

likely require single analyte methods (e.g., glyphosate/AMPA, paraquat/diquat, 

EBDCs). Priority 3 compounds may also include chemicals used in other countries, 

dependent upon their anticipated method behavior.

5.1.2.3 Laboratories should include all Priority 1 compounds, as many Priority 2 

compounds as possible, and Priority 3 compounds only when requested by MPD or as 

feasible with existing methods.

5.1.2.4 In some cases, PDP will authorize the development of new methods to detect certain 

compounds (e.g., triazole metabolites, phenoxies, formetanate hydrochloride).

5.2 Standards

 5.2.1 Ordering Analytical Standards

5.2.1.1 Standards may be obtained from the EPA Repository, registrants, or commercial 

vendors. When requesting standards from the Repository, identify your laboratory as a PDP 

laboratory in the comment section of the order form so that the Repository staff will know 

that the order takes precedence. If the request is urgent, note that in the Comment section of 

the order form as well.

The EPA repository is located at:
United States Department of Agriculture

Agricultural Marketing Service, Science & Technology

Pesticide Data Program

SOP No.: PDP-QC Page 6 of 47

Title: Chemical Compounds, PDP Commodity Grouping, Method Validation and Quality Control

Revision: 12 Replaces: 09/01/2021 Effective: 06/01/2023

EPA National Pesticide Standard Repository

Environmental Science Center

701 Mapes Road

Fort Meade, MD 20755-5350

Phone: (410) 305-2931

FAX: (410) 305-2999

https://www.epa.gov/pesticide-analytical-methods/national-pesticide-standard-repository

5.2.1.2 Procurement of standards from all sources must meet the following minimum 

requirements:

Availability of a current and valid “Certificate of Analysis” (CoA) (as a minimum 

requirement the certification shall identify the substance, its purity, and the production lot), 

traceability, and current expiration date. 

An exemption for CoA and current expiration date is allowed for extraneous environmental 

contaminants that are covered by FDA Action Levels and compounds that have been revoked 

and no longer have existing U.S. registrations. Extraneous environmental contaminants 

include aldrin, BHC, chlordane, chlordecone, DDD, DDE, DDT, dicofol, dieldrin, ethylene 

dibromide, heptachlor, heptachlor epoxide, lindane, and mirex. Examples of revoked 

compounds that no longer have existing U.S. registrations include parathion ethyl, 

chlorfenvinphos, and fenchlorphos.

For all other analytical standards, in some cases, a current and valid CoA may not accompany 

the analytical standard. In this case, the laboratory shall contact the vendor to determine if 

one is available; if one is not available, the laboratory shall document the lack of a current 

and valid CoA, as well as all information that is available from the vendor for the purpose 

of traceability and audit. 

5.2.2 Receipt of Analytical Standards

Custody of a standard begins when the standard is received in the laboratory. Each standard 

shall be given a code that uniquely identifies the standard from neat material to final dilutions. 

Receipt of standards shall be documented, and each standard shall be traceable. Records shall 
United States Department of Agriculture

Agricultural Marketing Service, Science & Technology

Pesticide Data Program

SOP No.: PDP-QC Page 7 of 47

Title: Chemical Compounds, PDP Commodity Grouping, Method Validation and Quality Control

Revision: 12 Replaces: 09/01/2021 Effective: 06/01/2023

include name, unique code, purity, lot number, date received, and expiration date (see 5.2.1.2 

for exemption).

5.2.3 Storage of Analytical Standards

5.2.3.1 Neat standards shall be kept in a separate standards freezer, preferably at 

approximately -20°C or lower unless degradation occurs at such temperatures. In these 

cases, neat standards shall be stored at the recommended temperature.

5.2.3.2 Stock standards and dilutions, including mixed standards, shall be kept in 

refrigerators or freezers separate from those used for samples. Stock standards and dilutions 

shall be stored in teflon-lined, screw-capped, glass bottles or sealed glass ampules.

5.2.3.3 Access to the freezers and refrigerators shall be controlled and standards usage 

documented through the use of appropriate records (e.g., log books). 

5.2.3.4 Refrigerator and freezer temperatures shall be checked either by taking readings 

each working day or by automatic temperature recording devices.

5.2.3.5 When a neat standard is removed from freezer storage, the standard should be stored 

in a desiccator while it is brought to room temperature to minimize the potential for 

hydrolysis.

5.2.4 Preparation of Stock Standard Solutions

Stock standard solutions shall be prepared in a separate standard preparation area to avoid 

contamination of samples with pesticide standards. Each stock standard shall be given a unique 

identifying code and shall be labeled with a minimum of: pesticide name, concentration, solvent, 

date of preparation, initials of preparer, and expiration date of solution. Written SOPs for stock 

standard preparation shall include the method for preparing standards, calculations used in 

standard preparation, documentation that provides for standard traceability, and safety 

guidelines. 

5.2.5 Preparation of Intermediate Dilutions

Intermediate dilutions, including mixed standards, shall be prepared in a separate standard 

preparation area. Each standard shall be given a unique identifying code and shall be labeled 
United States Department of Agriculture

Agricultural Marketing Service, Science & Technology

Pesticide Data Program

SOP No.: PDP-QC Page 8 of 47

Title: Chemical Compounds, PDP Commodity Grouping, Method Validation and Quality Control

Revision: 12 Replaces: 09/01/2021 Effective: 06/01/2023

with pesticide name, concentration, solvent, date of preparation, initials of preparer, and 

expiration date of solutions. Written SOPs shall include the method for standard preparation 

and documentation that provides for standard traceability.

5.2.6 Standard Checking

5.2.6.1 Stock solutions of neat pesticide standards not previously prepared or not currently 

in use in the laboratory shall be prepared in duplicate and the two standards compared to 

each other. Responses for standards of comparable concentrations must match within 15% 

relative percent difference (RPD):

RPD =

|RF1 − RF2|

[

RF1 + RF2

2

]

× 100

where RF1 is the response factor1 of the first analytical standard and RF2 is the response 

factor of the second standard. If standards do not match, potential sources of variation should 

be reviewed, and a third standard shall be made and compared. This process shall be 

continued until two matching standards are prepared.

5.2.6.2 New stock solutions that are prepared from neat pesticides currently used in the 

laboratory shall be compared to the old stock solution. The two standards must match within 

15% RPD. If the two standards do not match, the problem must be identified and solved 

before the standard is used for quantitation. A suggested approach is to make new dilutions 

of both the old and new standards to check for dilution errors. If no dilution errors are found, 

a second stock dilution should be made to determine whether an error was made in the 

original preparation from neat material. If these two stocks match, then the standard may be 

used. If they do not match, a third stock solution should be made. Whenever possible, 

duplicate injections shall be used.

5.2.6.3 Documentation of the standard checking process shall be kept through appropriate 

records (i.e. logs). Chromatograms of all standards shall be kept indicating the standard 

comparisons of old and new standards and the calculated difference. 

1 Area or height of each standard divided by the concentration of that standard.
United States Department of Agriculture

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Pesticide Data Program

SOP No.: PDP-QC Page 9 of 47

Title: Chemical Compounds, PDP Commodity Grouping, Method Validation and Quality Control

Revision: 12 Replaces: 09/01/2021 Effective: 06/01/2023

5.2.7 Expired Standard Verification

If a laboratory has an expired neat analytical standard and cannot obtain a replacement with a 

valid expiration date from an approved PDP vendor or the EPA National Pesticide Standard 

Repository, with a deviation from MPD on file, the laboratory may proceed with validation and 

analysis of samples using the expired standard under the following conditions:

5.2.7.1 If the standard is recertified by the vendor and new documentation is obtained, it 

shall be recorded in the laboratory’s standard records.

5.2.7.2 If the standard is not recertified, it shall be compared to an unexpired neat when one 

is available to verify its integrity.

5.2.7.2.1 If the two standards’ response factors are within 15%, the expired standard 

being used shall be considered fit for purpose and this data shall be recorded in the 

laboratory’s records.

5.2.7.2.2 If the two standards’ response factors are not within 15%, MPD shall be 

contacted.

5.2.7.2.2.1 If there are residues, MPD and the laboratory’s Technical Program 

Manager (TPM) and Quality Assurance Officer (QAO) shall develop an agreement 

on how to proceed with samples containing residues (e.g., re-extract and analyze with 

unexpired standard, code data as estimates, change to “unable to analyze,” etc.). The 

agreement shall be documented and recorded in the laboratory’s records. MPD will 

update any transmitted data in the MPD database.

5.2.7.2.2.2 If there are non-detects and the expired standard produces a response 

less than the response of the unexpired standard, the LOD shall be raised (consult 

with MPD to determine the level) and this information shall be recorded in the 

laboratory’s records. MPD will update any transmitted data in the MPD database. 

The expired standard being used shall be considered fit for purpose for qualitative 

analysis only and this declaration shall be recorded in the laboratory’s records.

5.2.7.3 If neither the requirements of 5.2.7.1 nor 5.2.7.2 can be met, then MPD must be 

contacted to discuss whether there is sufficient evidence of the integrity of the standard to 

warrant a deviation on a case-by-case basis.
United States Department of Agriculture

Agricultural Marketing Service, Science & Technology

Pesticide Data Program

SOP No.: PDP-QC Page 10 of 47

Title: Chemical Compounds, PDP Commodity Grouping, Method Validation and Quality Control

Revision: 12 Replaces: 09/01/2021 Effective: 06/01/2023

5.2.8 Working Dilutions/Mixed Standards

5.2.8.1 Working dilutions and mixed standards shall be checked to ensure integrity of the 

solutions. These solutions should be made as frequently as necessary to ensure that 

concentrations do not change and/or individual pesticides do not degrade. Each laboratory 

shall determine the frequency of remaking dilutions/mixed standards. Documentation 

supporting this decision shall be maintained. A suggested guideline is six months for stock 

mixed standards and one month for working dilutions. Some pesticides may require more 

frequent dilution from the stock.

5.2.8.2 An archive file of all old mixed standards shall be kept and the dates the standards 

were used shall be indicated. The archive file shall be maintained a minimum of five years.

5.2.8.3 All working/mixed standards shall be identified by a unique and traceable code. 

Working/mixed standard records shall contain a minimum of pesticide name, solvent, date 

of preparation, expiration date, and preparer. 

5.2.9 Detector Profiles

Standard retention time and response shall be characterized by analysis on the detectors used in 

each laboratory. These include but are not limited to: GC-MS/MS and LC-MS/MS. Libraries 

of all standards shall be developed for confirmatory instruments (GC-MS and LC-MS systems). 

5.2.10 Disposal of Analytical Standards

Each laboratory shall establish the proper procedures for disposal (e.g., disposal by a licensed 

contractor) of expired analytical standards (both neat standards and dilutions). Disposal shall 

be in accordance with the laboratory's Chemical Hygiene Plan and shall be documented.

5.3 Method Validation Background

5.3.1 Marker compounds and commodity groups were created to facilitate the validation 

and ongoing QC of the enormous number of combinations of pesticides and commodities 

included in PDP. Each concept seeks to group pesticides or commodities by common properties 

and exploits these common properties to reduce the possible combinations to a manageable 
United States Department of Agriculture

Agricultural Marketing Service, Science & Technology

Pesticide Data Program

SOP No.: PDP-QC Page 11 of 47

Title: Chemical Compounds, PDP Commodity Grouping, Method Validation and Quality Control

Revision: 12 Replaces: 09/01/2021 Effective: 06/01/2023

number. 

5.3.2 This method evaluation framework makes the following assumptions:

5.3.2.1 Commodities are grouped in such a way that assessment of method performance in 

one commodity in the group can be extended to apply to all commodities in the group. 

5.3.2.2 Marker pesticides are chosen to be representative of a broad range of similar 

pesticides. The assessment of method performance for these pesticides can be extended to 

apply to similar pesticides.

5.3.2.3 LOD is specific to a pesticide-commodity pair and must be evaluated for every 

pesticide-commodity pair.

5.3.2.4 Although a method may be extended to other commodities and pesticides, a 

minimum amount of LOD verification and recovery data must be obtained to confirm this 

assumption.

5.3.3 This SOP details various scenarios and their corresponding method validation 

requirements.

5.3.4 When problems occur, such as instrument reproducibility and/or linearity, an 

investigation of causes shall be conducted. A flow diagram is attached (see Attachment 1 –

Method Evaluation Flowchart) which further clarifies these concepts.

5.4 General Method Validation Requirements

5.4.1 Methods selected for use by PDP laboratories, and significant changes to approved 

methods, particularly those that will impact results, are subject to prior approval by MPD before 

commodity sampling begins. If significant changes are being considered during the course of 

testing, then the MPD approval should be sought prior to implementation. 

5.4.2 The laboratory shall complete all required method validation modules, with the 

exception of precision and accuracy data collection (extracted, analyzed, and reviewed), prior to 

the extraction of any routine analytical sample sets.
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SOP No.: PDP-QC Page 12 of 47

Title: Chemical Compounds, PDP Commodity Grouping, Method Validation and Quality Control

Revision: 12 Replaces: 09/01/2021 Effective: 06/01/2023

5.4.3 An extraction/detection system includes the whole method: extraction, clean-up, 

chromatography, and analytical technique. 

5.5 Method Validation Evaluation Guidelines

5.5.1 The following possible scenarios shall be followed for validation of new methods or 

changes/additions to existing methods:

5.5.1.1 Implementing a new method (5.6.1)

5.5.1.2 Changing an analytical method (5.6.2)

5.5.1.2.1 Extraction (5.6.2.1)

5.5.1.2.2 Post-extraction/pre-instrumentation (5.6.2.2)

5.5.1.2.3 Instrumentation - new Limit of Detection (LOD) (5.6.2.3)

5.5.1.2.4 Minor Modifications (5.6.2.4)

5.5.1.3 Adding a new commodity grouping (5.6.3)

5.5.1.4 Adding a raw agricultural commodity or a processed commodity to an existing 

commodity group. (5.6.4)

5.5.1.5 Adding pesticides related to marker pesticide groups to an existing commodity 

group (5.6.5) (see Attachment 2 – PDP Compound Groups, Pesticide Codes and Multiresidue Compound Groupings for Fruit and Vegetables).

5.5.1.6 Adding a new pesticide that is not related to marker pesticide groups to an existing 

commodity group. (5.6.6)

5.5.2 Evaluation takes place through the performance of method evaluation modules. 

These modules are chosen to meet the requirements of each scenario. The modules are:

• Establishment of LODs and Limits of Quantitation (LOQs) (5.10)

• Verification of LODs/LOQs (5.11)

• Determination of Method Range (from 1xLOQ to 10xLOQ) (5.13)
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SOP No.: PDP-QC Page 13 of 47

Title: Chemical Compounds, PDP Commodity Grouping, Method Validation and Quality Control

Revision: 12 Replaces: 09/01/2021 Effective: 06/01/2023

• Precision and Accuracy Data Collection at 2xLOQ (5.14)

• Method Evaluation Reporting (5.15)

5.5.3 Section 5.6 of this SOP lists each scenario and the modules that must be performed 

in that scenario. Sections 5.10 through 5.15 outline the detailed procedures to be followed for 

each module.

5.6 Method Validation Scenarios

The TPM and QAO will determine which scenario described in the following subsections applies 

for the analytes/commodities/methods pairings (see Attachment 2 – PDP Compound Groups, 

Pesticide Codes and Multi-residue Compound Groupings for Fruit and Vegetables). If local 

agreement cannot be reached, the MPD Director shall be contacted to determine which modules 

should be performed.

5.6.1 New method implementation – Proceed with:

• Establishment of LODs and (LOQs) (5.10)

• Verification of LODs/LOQs for all compounds (5.11)

• Determination of Method Range for marker compounds (5.13)

• Precision and Accuracy Data Collection for all compounds (5.14)

• Method Evaluation Reporting (5.15)

5.6.2 Method changes

5.6.2.1 Major Extraction Change - Examples would be using a different solvent, solid phase 

extraction (SPE) sorbent bed, or a new technique. Proceed with:

• Establishment of LODs and (LOQs) (5.10)

• Verification of LODs/LOQs for all compounds (5.11) 

• Determination of Method Range for marker compounds (5.13)

• Precision and Accuracy Data Collection for all compounds (5.14) 

• Method Evaluation Reporting (5.15)

5.6.2.2 Major changes in post-extraction/pre-instrumentation procedures (cleanup) -

Proceed with:

• Verification of LODs/LOQs for all compounds (5.11)
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SOP No.: PDP-QC Page 14 of 47

Title: Chemical Compounds, PDP Commodity Grouping, Method Validation and Quality Control

Revision: 12 Replaces: 09/01/2021 Effective: 06/01/2023

• Determination of Method Range for marker compounds (5.13)

• Precision and Accuracy Data Collection for all compounds (5.14)

• Method Evaluation Reporting (5.15) 

5.6.2.3 Instrumentation Changes - The TPM and QAO will determine if the instrument 

change warrants completion of the following sections. This is dependent upon the extent of 

modification. If local agreement cannot be reached, the MPD Director shall be contacted 

for further resolution.

For new LOD - Proceed with:

• Establishment of LODs/LOQs for all compounds (5.10)

• Verification of LODs/LOQs for all compounds (5.11)

• Method Evaluation Reporting (5.15)

The laboratory shall use best professional judgment to determine if Precision and Accuracy 

Data Collection (subsection 5.14) is necessary.

5.6.2.4 Minor modifications of existing method - The TPM and QAO will determine which 

portions of the following sections will be completed. This is dependent upon the extent of 

modification. If local agreement cannot be reached, the MPD Director shall be contacted 

to determine which sections should be performed. 

• Establishment of LODs and LOQs of affected analytes (5.10)

• Verification of LODs/LOQs of affected analytes (5.11)

• Determination of Method Range of affected markers (5.13) 

• Precision and Accuracy Data Collection of affected analytes (5.14)

• Method Evaluation Reporting (5.15)

5.6.3 Adding a new commodity group (see Section 5.9) - Proceed with:

• Verification of established LODs/LOQs for all required pesticides in the new 

commodity (5.11)

• Determination of Method Range for the marker pesticides (5.13) 

• Precision and Accuracy Data Collection for all required analytes (5.14)

• Method Evaluation Reporting (5.15)

5.6.4 Adding a raw agricultural commodity or processed commodity (i.e., 
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Title: Chemical Compounds, PDP Commodity Grouping, Method Validation and Quality Control

Revision: 12 Replaces: 09/01/2021 Effective: 06/01/2023

canned/frozen/dried/ juice) to an existing commodity group (see Section 5.9) - Proceed with:

• Verification of established LODs/LOQs for all required pesticides (5.11)

• Precision and Accuracy Data Collection for all required pesticides (5.14)

• Method Evaluation Reporting (5.15)

The laboratory shall use best professional judgment to determine if additional validation is 

necessary based on matrix behavior.

5.6.5 Adding pesticides related to the marker pesticide groups to an existing commodity 

group (see Section 5.9) – Proceed with:

• Establishment of LODs and LOQs for each pesticide added (5.10)

• Verification of LODs/LOQs for each pesticide added (5.11)

• Precision and Accuracy Data Collection for each pesticide added (5.14)

• Method Evaluation Reporting (5.15)

5.6.6 Adding pesticides that are not related to the marker pesticide groups to an existing

commodity group (see Section 5.9) - (For example, the addition of imidacloprid analyzed by the 

same multiresidue procedure. The new pesticide may then become a marker pesticide for similar 

pesticides that are later added.) - Proceed with:

• Establishment of LODs and LOQs for each pesticide added (5.10)

• Verification of LODs/LOQs for each pesticide added (5.11)

• Determination of Method Range for compound(s) that is/are to become marker(s) 

(5.13)

• Precision and Accuracy Data Collection for each pesticide added (5.14)

• Method Evaluation Reporting (5.15)
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Title: Chemical Compounds, PDP Commodity Grouping, Method Validation and Quality Control

Revision: 12 Replaces: 09/01/2021 Effective: 06/01/2023

Table Summarizing Section 5.6 – Method Validation Scenarios Establish LODs/LOQs (5.10)

Verify LODs/LOQs (5.11)Determine Method Range (5.13)Precision and Accuracy (5.14)Method Evaluation Reporting (5.15)

New Method Implementation (5.6.1) X X X X X

Major Change – Major Extraction Change (5.6.1.2) X X X X X

Major Change – Post Extraction Change (5.6.2.2) X X X X X

Major Change – Instrumentation Change (5.6.2.3) X X * X

Minor Change of Existing Method (5.6.2.4) * * * * *

New Commodity Group (5.6.3) X X X X

Add Commodity to Commodity Group (5.6.4) X X X

Add Pesticides related to Markers to Commodity 

Group (5.6.5) X X X X

Add Pesticides not related to Markers to Commodity 

Groups (5.6.6) X X X X X

* Laboratory shall use best professional judgment to determine if necessary. Consult MDP Director 

as needed.

5.7 Marker Pesticides 

5.7.1 Assigning Compounds to Marker Groups

5.7.1.1 Compounds are placed into marker groups based on a combination of analyte 

chemistry and method performance behavior when requested by a laboratory. Initial 

compound designations are made by the Technical Advisory Group (TAG), with applicable 

analytical laboratory input based on known method behavior, if those data are available. For 

new compounds, behavior data may not be available.
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Title: Chemical Compounds, PDP Commodity Grouping, Method Validation and Quality Control

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5.7.1.2 Final marker group assignment, and any marker group assignment changes, are based 

on laboratory experience. MPD maintains an “Effective Date” field that tracks initial group 

assignment as well as any changes in that initial assignment.

5.7.2 Multi-residue Screening

5.7.2.1 A laboratory may choose to use marker groups, rotate spike mixtures between 

analytical sets, or spike all compounds analyzed, as long as each extraction/detection 

system is adequately represented within each set.

5.7.2.2 For laboratories using marker groups, each laboratory shall select at least one 

compound from each applicable group (see Attachment 2 – PDP Compound Groups, 

Pesticide Codes and Multi-residue Compound Groupings for Fruit and Vegetables) to serve 

as a marker pesticide. Applicable groups are those that contain at least one compound 

analyzed by that laboratory for that commodity. For each applicable group, a marker 

pesticide shall be included for each extraction/detection system used to analyze that group. 

Marker groups are only added to Attachment 2 when requested. 

5.7.2.3 For laboratories rotating spike mixtures between analytical sets, each laboratory 

shall ensure that each extraction/detection system is adequately represented within each 

set.

5.7.2.4 For laboratories analyzing multiple commodities, a single list of marker compounds 

may be specified to represent all commodities. The lists of required compounds for 

commodities analyzed should be combined and at least one compound from each applicable 

group chosen to serve as a marker compound.2

5.7.3 Selected/single analyte residue studies utilize the selected analyte as the marker 

pesticide.

5.7.4 “Marginal Performing Analytes” are analytes that do not meet linearity, calibration 

integrity, ion ratio, recovery (individual or mean), or precision and accuracy criteria during 

method validation or continuing quality control (QC) as specified in Section 5.18. Marginal 

2 For laboratories analyzing multiple commodities, compounds in single groupings only need apply to that required 

commodity.
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Title: Chemical Compounds, PDP Commodity Grouping, Method Validation and Quality Control

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performing analytes are determined in conjunction with MPD.

5.8 Process Control Compounds

Samples analyzed by each extraction/detection system shall include the analysis of a process control

compound. More than one process control may be required. The laboratory shall make every effort 

to choose a compound that is not expected to be an incurred residue.

5.9 PDP Commodity Groupings

Fruits and Vegetables: Apples (AP), Apple Juice (AJ), Applesauce (AC), Asparagus (AS), Avocado 

(AV), Baby Foods (see Attachment 3 for corresponding codes), Bananas (BN), Basil (BS),

Blackberries (BK), Blueberries (BB), Broccoli (BR), Cabbage (CG), Canned Beans (BC), Canned 

Beets (BT), Canned Cranberries (RC), Canned Garbanzo Beans (ZB), Canned Olives (OL), Canned 

Peaches (CC), Canned Peas (SD), Canned Pineapples (NC), Canned Spinach (SC), Canned Sweet 

Corn (CD), Canned Tomatoes (TC), Cantaloupe (CN), Carrots (CR), Cauliflower (CF), Celery (CE),

Cherries (CH), Cherry Tomatoes (CT), Cilantro (CL), Collard Greens (GL), Cranberries (CA), 

Cucumbers (CU), Dried Garbanzo Beans (ZD), Dried Plums/Prunes (PD), Eggplant (EP), Frozen 

Blueberries (BZ), Frozen Peaches (HZ), Frozen Peas (PS), Frozen Raspberries (RZ), Frozen 

Spinach (SF), Frozen Strawberries (SZ), Frozen Sweet Corn (CS), Frozen Winter Squash (WZ), 

Grapefruit (GF), Grapes (GR), Grape Juice (GJ), Green Beans (GB), Green Onions (GO), Greens 

(GS), Honeydew Melons (HD), Hot Peppers (HP), Kale (GK), Kiwi (KW), Lettuce (LT), Mangoes 

(MA), Mushrooms (MU), Mustard Greens (MG), Nectarines (NE), Onions (ON), Oranges (OG), 

Orange Juice (OJ), Papaya (YA), Peaches (PC), Pears (PE), Pear Juice (PJ), Pineapples (PN), Plums 

(PU), Potatoes (PO), Radish (RD), Raspberries (RS), Snap Peas (SN), Spinach (SP), Strawberries 

(ST), Summer Squash (SS), Sweet Bell Peppers (PP), Sweet Cherries (CH), Sweet Corn (CB), Sweet 

Potatoes (SW), Tangerines (TA), Tomatillos (TT), Tomatoes (TO), Tomato Paste (TP), Watermelon 

(WM), Winter Squash (WS)

Cereal Grains (Low Oil): Barley (BY), Corn Grain (CO), Oats (OA), Rice (RI), Wheat (WH), 

Wheat Flour (WF)

Cereal Grains (High Oil): Almonds (AL), Peanut Butter (PB), Soybeans (SY)
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Title: Chemical Compounds, PDP Commodity Grouping, Method Validation and Quality Control

Revision: 12 Replaces: 09/01/2021 Effective: 06/01/2023

Animal Tissue/High Protein: Beef (adipose – BA, liver – BL, muscle – BM), Catfish (FC), Eggs 

(EG), Pork (adipose – KA, muscle – KM), Poultry (adipose – PA, liver – PL, muscle – PM, breast 

– PR, thigh – PT), Salmon (FS)

Dairy Products: Butter (BU), Heavy Cream (CM), Milk (MK)

Water: Untreated Drinking Water (WU), Treated Drinking Water (WR), Bottled Water (WB), 

Groundwater (WG)

Single Commodities: For example, Corn Syrup (CY), Dairy-based Infant Formula (DF), Raisins 

(RA), Soy-based Infant Formula (YF), Honey (HY).

5.9.1 Based on their experience with a commodity, laboratories may request changes to 

the assigned commodity groupings from the MPD Director.

5.9.2 Environmental Protection Agency (EPA), Codex, and Food and Drug Administration 

(FDA) Pesticide Analytical Manual (PAM) commodity grouping information and the FDA 

Information for percent fat, water, sugar and pH content for Commodity Groupings can be found 

in Attachments 3 and 4 of this SOP.

5.10 Establishment of LODs and LOQs

5.10.1 Method Noise

5.10.1.1 Method noise is the combination of instrument noise and the matrix noise 

contributions.

5.10.1.2 Method noise determination must be completed for all required PDP analytes.

5.10.1.3 Method noise will be determined utilizing instruments and operating conditions, 

which are routinely used for the analysis of samples. Noise for the LOD and LOQ 

calculations will be determined by examining chromatograms of the blank commodity in the 

chromatographic time segment of the pesticides of interest.

5.10.2 Establishment of LOD
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5.10.2.1 LOD may be estimated by whatever means the laboratory chooses to employ, but 

the response shall be at least 3x signal to noise.

For MS systems, ions used for quantitation and for qualitative analysis/confirmation shall 

meet the 3x signal to noise requirement.

For example: 1) take two equal portions from the same matrix blank extract; 2) spike one 

aliquot with a known amount of the analyte of interest; 3) inject both aliquots under the same 

conditions; 4) magnify the baseline of the unfortified blank at the analyte retention time 

window of interest to obtain the instrument response for the tallest (height) or the broadest 

(area) noise; and 5) convert the response into concentration (ppm, ppb, or ppt) from the 

known concentration of the spiked extract. Compare the two concentrations (blank vs. 

spiked) to estimate the LOD.

5.10.2.2 LODs may be established at a level greater than 3x noise.

5.10.2.3 In addition to signal-to-noise considerations, LODs estimated for zero noise 

instruments (e.g. triple quadrupoles) may also include consideration of replication injection 

data (e.g. injecting an LOD standard 10x).

5.10.2.4 The reported LOD shall be the highest value obtained using the validated 

method. For instance, for dual column systems, the confirmatory column LOD must be AT 

LEAST that of the primary/quantitative column.

5.10.2.5 For multi-peak compounds, such as many of the pyrethroids, the laboratory 

may base the LOD on the largest peak if a mass spectrometry system is used for both 

quantitation and confirmation. If other systems are used for quantitation, the laboratory may 

base the LOD on the larger peak if the smaller peak is <20% of the total response.

5.10.2.6 LOD is method dependent and shall be experimentally verified in matrix as 

detailed in Section 5.10.1.

5.10.3 Establishment of LOQ

5.10.3.1 LOQ will be calculated/determined for each analyte in each commodity 
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tested following the establishment of LOD. LOQ is typically equal to LOD, but this is not 

required. 

5.10.3.2 For all detection systems other than mass spectrometry, LOQ will be 

established by multiplying the response of method noise level by at least ten and then 

converting the total response into concentration (i.e., ppm, ppb, or ppt), or by multiplying 

the LOD by no less than ten/thirds (10/3) if the LOD is established above 3x method noise. 

5.10.3.3 For mass spectrometric systems, ions to be used for qualitative 

analysis/confirmation shall be at least 3x signal to method noise. Ions to be used for 

quantitation shall be at least 10x signal to method noise. 

5.10.3.3.1 In order to maximize the number of compounds screened by MS systems 

while maximizing the number of scans per second and dwell times, it may be desirable 

to perform the initial identification and quantitation using fewer than three ions for 

some or all of the compounds. Presumptive-positive samples shall be re-injected or 

data reprocessed to meet all MS confirmation criteria.

5.10.3.4 The reported LOQ shall be the highest value obtained using the validated 

 method. During method validation, if LOQs have increased by 50% from previous

 validations, or if more than one previously validated Priority 1 compound is unvalidated,

 then the laboratory shall consult MPD. MPD will compare increased LOQs to the tolerance

for the pesticide/commodity pair.

5.11 Verification of LODs/LOQs

5.11.1 During method validation, all calculated or established LODs must be verified by 

fortifying duplicate blank commodities at approximately the LOD level and subjecting them to 

the analytical method for each extraction/detection system used in the analysis of PDP samples. 

In the instance where the LOD equals LOQ, this verification suffices for the LOD and LOQ. If

LOD does not equal LOQ, LOD verification is required and the LOQ established as specified 

in section 5.10.3 is sufficient. If method range (see subsection 5.13) is performed when LOD

equals LOQ, then section 5.11 is not required for those compounds where method range was 

performed. If method range (see subsection 5.13) is performed when LOD does not equal LOQ,

then section 5.11 shall be performed to verify LODs for those compounds where method range 
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Title: Chemical Compounds, PDP Commodity Grouping, Method Validation and Quality Control

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was performed.

5.11.2 Verification consists of the observation of detectable peaks in the chromatogram at 

3x the current noise level (run within the last three months). Variability is expected to be high. 

Therefore, recoveries can be reported as present or not present. If detectable peaks are not 

observed, the LOD must be re-estimated and the verification repeated.

5.11.3 Prepare summary form(s) of the acquired data for all systems and all columns used 

for analysis and/or confirmation (see Attachment 5 - Method Evaluation Reporting Forms).

5.11.4 For water only, the LOD for each reported compound shall be verified, at least every 

two years, by extraction of a single LOD spike. Reporting these results to MPD is optional. If 

the LOD Verification Form in Attachment 5 is used, then recording only one LOD spike is 

required.

5.12 Changing LODs 

5.12.1 LODs may be raised for analytes in an individual sample set at the discretion of the 

TPM.

5.12.2 LODs may not be lowered without verification subject to the analytical method, TPM 

approval, and QAO review. 

5.13 Determination of Method Range

5.13.1 During method validation, samples fortified with marker compounds (only marker 

compounds are required, however, other compounds may be used in addition to the markers, if 

desired) are to be run through the entire analytical method on the primary analytical system. If 

more than one type of chromatography/detector system GC-MS/MS versus LC-MS/MS are to 

be used for quantification, they must be likewise evaluated.

5.13.2 Fortify samples in triplicate at approximately 1xLOQ, 5xLOQ, and 10xLOQ for each 

marker or compound being validated. Process these fortified samples through the entire 

analytical method. A reagent and matrix blank shall be subjected to the analytical method along 

with the fortified samples.
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Title: Chemical Compounds, PDP Commodity Grouping, Method Validation and Quality Control

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5.13.3 For each data point, calculate the Percent Recovery compared to known standards to 

three significant figures if greater than 100% or to two significant figures if less than 100%.

5.13.4 Calculate the mean Percent Recovery (%R) and Coefficient of Variation (%CV) for 

each level. A definition of Horwitz expected intralaboratory and interlaboratory %CVs may be 

found in SOP PDP-Glossary. The appropriate values may be used as a guideline when evaluating 

data.

5.13.5 Prepare summary form(s) of the acquired data by analyte, level, and commodity 

group (see Attachment 5 - Method Evaluation Reporting Forms).

5.13.6 Method Range Extension

If more than 20 findings per life of the commodity for a particular analyte/commodity pair 

exceed the highest validated spiking level, then in order to verify the ability of the method to 

extract the analyte at the higher level, the laboratory shall fortify at least one spike at or above 

the level of the highest finding. Reagent and matrix blanks shall accompany these spikes. If the 

matrix spike recoveries do not meet QC criteria (per section 5.18), any affected findings shall 

be coded (or recoded) as estimates. Method range extension spikes may be reported via the 

Remote Data Entry (RDE) tool as “other” spikes. Marker pesticide spikes may be used to 

represent other compounds in that group. Method range extension for a given commodity can

represent another commodity in that group. Laboratories may perform the range extension at 

various times: 

• preemptively during initial validation (based on intelligence or experience with the 

commodity),

• in subsequent batches following the high finding,

• periodically (e.g. annually) to conserve resources, or

• internal blind check samples may be used for this purpose.

Method range extension results should be reported to MPD following QA review. MPD expects 

any coding changes for calendar year samples to be submitted by May 31st following the end of 

the calendar year. This does not remove the requirement to report all data sets for the calendar 

year by March 31st of the following calendar year.

5.14 Precision and Accuracy Data Collection
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Title: Chemical Compounds, PDP Commodity Grouping, Method Validation and Quality Control

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5.14.1 The precision and accuracy data collection shall be compiled from each 

commodity. Each marker, single analysis, new or other required PDP analyte shall be spiked 

at 2xLOQ and evaluated using a minimum of seven data points.

5.14.2 The required data points shall be obtained from:

• 2xLOQ data points completed after Determination of Method Range

and/or

• data points from matrix spikes analyzed concurrently with samples.

These two options provide slightly different data. The second option is preferable since it 

provides information about the repeatability of the method over time. The first option is 

permitted when running concurrent spikes would extend the data collection over more than six 

months and/or concurrent spikes would make the size of sample sets unmanageable. For each 

commodity, the labs are to report all seven precision and accuracy data points with the validation 

data.

5.14.3 For each data point, calculate the Percent Recovery compared to known standards to 

three significant figures if greater than 100% or to two significant figures if less than 100%.

5.14.4 Calculate the mean Percent Recovery (%R) and Coefficient of Variation (%CV) for 

each pesticide using the seven data points. A definition of Horwitz expected intralaboratory 

and interlaboratory %CVs may be found in SOP PDP-Glossary. The appropriate values may 

be used as a guideline when evaluating data and/or determining whether analytes should be 

considered a Marginal Performing Analyte. In addition, Marginal Performing Analytes may 

be determined based on linearity, calibration integrity, or individual recovery values.

5.14.5 Prepare summary form(s) of the acquired data (see Attachment 5 - Method 

Evaluation Reporting Forms). Refer to Sections 5.17 for PDP acceptance criteria.

5.15 Method Evaluation Reporting

5.15.1 The methodology, method evaluation records, summary form(s), chromatograms, 

and any other supporting data generated during method evaluation shall be maintained by the 

laboratory.
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5.15.2 Local Approval

5.15.2.1 Any request for a written modification of an approved analytical method 

shall be reviewed and approved by the QAO and TPM.

5.15.2.2 All validation documentation shall be reviewed and approved by the QAO 

and TPM.

5.15.3 Letter of Intent

5.15.3.1 Once the Verification of LODs and LOQs and Determination of Method 

Range has been completed, reviewed, and approved by the QAO and TPM, a Letter of Intent 

shall be submitted to the MPD Director with copies to the Method Validation Coordinator 

and the assigned MPD laboratory liaison stating that these modules have been completed, 

reviewed, and approved and will be submitted at a later date with the Precision and Accuracy 

Data. 

5.15.3.2 This letter shall also include a list of commodity(ies) and analyte(s) with their 

LOD(s) that the laboratory intends to analyze and shall be submitted within 90 days of the 

applicable commodity entering the program. 

5.15.3.3 The Letter of Intent is not required if all required method validation data will 

be/is submitted within 90 days of the commodity entering the program.

5.15.3.4 MPD will perform a brief preliminary review and, upon laboratory request, 

will issue a provisional letter of concurrence allowing the laboratory to transmit data to their 

MPD laboratory liaison for review while the full method validation package undergoes a 

multi-level review by MPD. Data may be changed, in consultation with the lab, based on the 

results from the full method validation package review.

5.15.4 Upon conclusion of the Precision and Accuracy Data Collection module, summary 

form(s) of validation documentation, and a brief narrative shall be sent by email to the MPD 

Director with copies to the Method Validation Coordinator and the assigned MPD laboratory 

liaison with a cover memo detailing the submission stating which version of the PDP-QC SOP

(PDP-QC SOP version X) was followed to determine the scenario(s) and module(s) that the 
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submission is intended to represent. 

5.15.5 A narrative accompanying the validation documentation shall include the following.

5.15.5.1 Description of the method.

5.15.5.2 Identification of any data that is only intended to be used for confirmation. 

Otherwise, MPD will evaluate the data as if quantitation will be performed on the 

instrument/analyte combination. 

5.15.5.3 Requests for designation of any analytes as Marginal Performing Analytes -

if MPD agrees to consider any analytes as Marginal Performing Analytes, that designation 

will be documented in the Letter of Concurrence.

5.15.5.4 Identification of previous method validation data used. The laboratory shall 

be responsible for clearly identifying the data used and the rationale for their use. For 

example, if a previously validated commodity returns and the laboratory has not made any 

method changes and will be using the same instrumentation, the laboratory shall submit a 

letter to MPD explaining how the previous validation data will be used.

Example narrative for a data package:

Enclosed is the complete method validation summary of all compounds we are screening for in 

commodity “y” to support the addition of the commodity to the 2022 PDP program. The method 

validation was performed according to the requirements of PDP-QC SOP version X. The 

specific scenario used in validation was 5.6.1, New Method Implementation. Required modules 

included establishment and verification of LODs and LOQs, determination of method range, 

precision and accuracy data collection, method evaluation reporting for GC/MSD, GC/FPD, 

GC/XSD, and LC/MS/MS instrumentation. For compound “a”, GC/FPD is the primary 

detection system and LC/MS/MS data is intended for confirmation purposes only. The 

following analytes were dropped during method development due to difficulty in analysis (e.g., 

solubility, poor chromatography, sensitivity, and/or loss in SPE cleanup): compound “b”, 

compound “c”, and compound “d”. Due to problems with recovery, the following analytes 

should be considered Marginal Performing Analytes and, if it is agreed, will be coded as such 

in reporting: compound “e”, compound “f”, and compound “g”. If there are questions about this 
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submission please contact: XXXXXX. All references to this submission should use QA# ###-

####.

Example narrative for a previously validated returning commodity with no method, analyte, or 

instrumentation changes:

In 2022, commodity “y” returned to the 2022 PDP program. This commodity was previously 

validated in 2017 and there have been no changes to the method, target analytes, and 

instrumentation since then. Therefore, the 2017 validation data submitted on Month/Day/Year, 

is still applicable. If there are questions about this submission, please contact: XXXXXX. All 

references to this submission should use QA# ###-####.

An example format for the submission follows:

Title

Summary to include purpose, results, data anomalies.

Methods

Sample Preparation (example):

• 50g homogenized sample extracted with 100 ml ACN by gently mixing

• 5ml extract purified by a C-18 SPE cartridge, eluted with MeOH, and concentrated to 5ml

• 1 ml eluate further purified by florisil SPE and eluted with 5 ml 50:50 hexane/acetone

• Eluate dried down to 0.5 ml, re-suspended in acetone, and filtered

• Derivatizaton accomplished by reaction with dansyl chloride.

Analysis (example):

• Instrument GC/HPLC/detector

• Column (DB-)

• Post-column derivatization (where applicable).

5.16 Method Validation Evaluation by MPD

5.16.1 Letter of Intent

5.16.1.1 Letters of Intent shall be tracked and maintained in centralized files by the 

Method Validation Coordinator.
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5.16.1.2 The MPD laboratory liaison assigned to that facility submitting a Letter of 

Intent shall review the letter and verify the submitted LOD/LOQ values against 

electronically submitted data (upon availability) and, upon laboratory request, issue a 

provisional letter of concurrence (see Section 5.15.3).

5.16.2 Method Validation Data Packages

5.16.2.1 After receipt by the MPD Director, Method Validation coordinator, and

MPD laboratory liaison, method validation data packages undergo a multi-tiered review by 

MPD. Details of this review process are specified in SOP PDP-ADMIN. 

5.16.2.2 The method validation package is reviewed to ascertain the physical presence 

and completeness of data submitted for method validation and to determine whether these 

data adhere to PDP criteria and are to be considered validated.

5.16.2.3 Data that do not meet PDP criteria for linearity, calibration integrity, ion 

ratios, individual or mean recovery (50-150%) or reproducibility (%CV values within the 

expected Horwitz intralaboratory values) shall be reported to MPD. MPD and the 

laboratory shall use scientific judgment to determine whether the compound shall be 

considered validated, designated as a Marginal Performing Analyte, or designated as 

unvalidated for that pesticide/commodity pair. 

Note: The Horwitz values are used as guidelines only and do not preclude a compound from 

being considered validated.

5.16.2.4 Once the MPD review of the method validation package has been completed, 

the laboratory TPM and QAO will receive a Letter of Concurrence that identifies the status 

of the instrument/detector results for the commodity/analyte pairing (e.g., validated, not 

validated, Marginal Performing Analyte, incomplete). If the data are deemed incomplete by 

MPD, the Letter of Concurrence will identify the deficiency and include a request for the 

remaining data (e.g., monitoring of daily matrix fortifications or addition of a spike 

compound with the same functional group to the fortification profile).

5.16.2.5 Once a compound is designated as a Marginal Performing Analyte, that 

designation shall not be changed unless approved by the MPD Director.
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5.17 Blanks and Spikes Required Per Set and Continuing QC

5.17.1 Sample set

A sample set is a group of unknown samples, which are spiked individually with the designated 

process control(s), extracted with the required QC samples, and analyzed with the applicable 

required QC samples. Each set shall not exceed 35 unknown samples. Required QC samples 

per set consist of a reagent blank, matrix blank, and matrix spike(s).

Each laboratory is given the option of combining two or more small sets into a larger set (e.g., 

peaches month A + peaches month B or apples month A + peaches month A). If the larger set 

contains two commodities, then the set shall contain a matrix blank of each commodity and a 

matrix spike(s) in at least one of the commodities.

5.17.2 Reagent Blank

A reagent blank is intended to demonstrate glassware cleanliness and total system integrity. It 

shall be prepared by subjecting an amount of distilled water equivalent to that contained in an 

average sample to the entire analytical process. For consistency in the preparation of the reagent 

blank, it shall be assumed that an “average” (includes fresh, canned, or frozen) fruit or vegetable 

sample contains 80% water. If contamination or interferences in the retention time window of 

the pesticide of interest is present in excess of the calculated LOQ, appropriate action must be 

taken and documented.

5.17.3 Matrix Blank

A matrix blank is intended to demonstrate the behavior of a substrate within an analytical 

system. Ideally, a matrix blank should be void of any compounds of interest. A matrix blank 

may be a previously characterized sample of the same commodity. If a suitable sample is not 

available, a portion of one of the samples may be randomly selected and used as a matrix blank. 

If an incurred residue is found in the matrix blank, which has been chosen from the sample set, 

determine if the same residue is incurred in the actual sample and is not present in other samples 

in the same set. If this condition cannot be met, appropriate action must be taken, such as 

reviewing reagent blank information. 

5.17.4 Matrix Spike
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A matrix spike is intended to reflect the behavior of a chemical in a substrate within an analytical 

system. The matrix spike indicates the behavior of the chemical for the entire sample set.

Analysis of a matrix spike provides valuable information on matrix interference effects as a 

result of the co-eluted matrix components, affecting the accuracy or detection capability for the 

analytes of interest.

5.17.4.1 A second portion of the same material used for the matrix blank shall be used 

for the matrix spike(s). Laboratories may design their QC spiking schemes to meet their 

needs. A laboratory may choose to use marker groups as defined in Section 5.7 of this SOP, 

rotate spike mixtures between analytical sets, or spike all compounds analyzed, as long as 

each extraction/detection system is adequately represented within each set and the minimum 

requirement of all compounds reported by the laboratory to be spiked at least quarterly in 

each commodity is met. 

5.17.4.2 The spike shall be added prior to extraction at approximately 2x LOQ (or 

less). Additional spikes may be added to satisfy the quarterly spiking of each commodity 

with all reported compounds, as part of a validation study, or to familiarize a laboratory with 

pesticides that have not been previously analyzed. More than one matrix spike shall be 

required if necessary for all spiked compounds to be separated during the chromatographic 

process. If a laboratory has combined commodities within a set, then the QA/QC Recovery 

Form shall indicate which commodity was used for the matrix spikes. Results for all spiked 

compounds shall be reported to MPD through normal RDE procedures.

5.17.4.3 The matrix spike(s) shall meet the criteria requirements specified in section

5.18.2. All reported compounds (markers, required, and any other compound reported by 

that laboratory) shall be spiked at least quarterly for each commodity. All components of 

sample sets shall be subject to the same analytical process as detailed in the method SOPs.

5.17.4.4 Recoveries for compounds designated as Marginal Performing Analytes shall 

be coded with a “P” (Marginal Performing Analyte) in the Exception field of the QA/QC 

Recovery form.

5.17.4.5 If reported, recoveries for unvalidated compounds shall be coded with a “U” 

(Unvalidated Residue) in the Exception field of the QA/QC Recovery form.

5.17.4.6 Incurred residue levels may be subtracted from the spike recovered prior to 
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calculating the percent recovery if the conditions specified in SOP PDP-DATA are met.

5.17.5 Reporting Fortification Recoveries

5.17.5.1 “Fresh” spikes are matrix spikes fortified, extracted, and analyzed with that 

set of analytical samples. Fresh values reported may be the original, re-injected, realiquoted, or re-extracted (from homogenate) determination value. The results reported may 

be the value from primary detection system or the averaged value (e.g., dual column results 

averaged).

5.17.5.2 “Other” spikes are additional fortifications reported by the laboratory. The 

laboratory can request that MPD adds a new spike type code as needed. Examples of “other 

spike” types are freezer, storage, failed fresh values, or “extra” QA spikes performed by the 

laboratory.

5.17.6 Quarterly 2xLOQ Spikes

5.17.6.1 All reported compounds (markers, required, and any other compounds 

reported by the laboratory) shall be spiked at least quarterly at 2x LOQ (or less) for each 

commodity.

5.17.6.2 The laboratory may choose to rotate spikes on a regular basis as long as the 

requirements in Subsection 5.17.4.1 are met. 

5.17.6.3 The spike results shall be reported to MPD via RDE (the preferred option) or 

in Excel spreadsheets. Results shall also be addressed in the semi-annual QA Reports 

submitted to MPD.

5.17.7 Process Control Spikes

A process control spike is intended to assure the integrity of a particular sample within an 

analytical system.

5.17.7.1 Each sample set component, except the reagent and matrix blanks, shall be 

spiked with a process control at approximately 5x the Limit of Quantitation (LOQ) prior to 
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the extraction step of the analytical procedure. However, if the intent of the process control 

is to monitor the percent recovery of a clean-up step, or of a derivatization, then the process 

control shall be added to the extract before the clean-up or derivatization step. 

5.17.7.2 The laboratory shall make an effort to choose a compound that is not expected 

to be an incurred residue. The value reported as “percent recovery” may be the original, reinjected, re-aliquoted, or re-extracted (from homogenate) determination value [either value 

from primary detection system or averaged value (e.g., dual column results averaged)].

5.17.8 QA/QC Recovery Form Codes

The following codes shall be entered in the Exception field of the QA/QC Recovery form. See 

Section 5.17.4 for additional details.

Code QA Spike Exception

E Estimated

I Incurred Residue

M Matrix Interference

N Not Recovered

P Marginal Performing Analyte

S Incurred Residue Subtracted

U Unvalidated Residue

5.18 Criteria for Method Validation and Continuing QC

5.18.1 Method Validation Criteria

5.18.1.1 PDP criteria for percent recovery for determination of method range and 

precision and accuracy data collection is 50-150%; however, it is expected to be as close to 

100% as feasible. 

5.18.1.2 Horwitz intralaboratory values are used as a guideline for determining 

reproducibility acceptability. The laboratory shall indicate any compounds that they feel are 

not acceptable and/or those that should be classified as Marginal Performing Analytes. 
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These laboratory recommendations are subject to approval by MPD.

5.18.1.3 Analytes that do not meet method validation criteria for linearity, calibration 

integrity, ion ratios, recovery (individual or mean), or precision (%CV) shall be reported to 

MPD with the method validation. Rather than not including them in the laboratory's 

screening list, MPD and the laboratory may decide that marginal data are preferable to no 

data. These compounds shall be designated as Marginal Performing Analytes. Details on 

MPD review of method validation data can be found in Section 5.15.

5.18.2 Matrix Spike Criteria

5.18.2.1 All spiked compounds shall have recoveries between 50 and 150%, within 

the statistically calculated range, or within a range agreed upon with MPD.

5.18.2.2 If a large number of analytes are in the spike, it becomes statistically likely 

that a few will be outside control limits. This may not indicate that the system is out of 

control. The laboratory shall have written criteria for when corrective action(s) will be 

necessary.

5.18.2.2.1 Some analytes may not be optimally recovered during method validation 

trials. Recoveries may be low and/or erratic and rather than not including them in the 

laboratory's screening list, the laboratory may consult with MPD to determine if marginal 

data may be preferable to no data. If reported by the laboratory, the codes for Marginal 

Performing Analytes shall be utilized. MPD will note the use of Marginal Performing 

Analytes in the Letter of Concurrence and the use of marginal performer codes for 

particular analyte/commodity pairs. Once a compound is designated as a Marginal 

Performing Analyte, that designation shall not be changed unless approved by the MPD 

Director.

5.18.2.2.2 Some analytes that behave acceptably during method validation may behave 

unacceptably during the analysis of routine batches. This may be due to the fact there is 

more commodity variability among actual samples than there is in the limited matrix 

utilized for method validation batches. As above, rather than dropping these analytes 

from the screening list, the laboratory should consult with MPD to determine if they 

should be reclassified as Marginal Performing Analytes. If a compound is reclassified 

as a Marginal Performing Analyte, an e-mail notification to the MPD Director, with a 
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Title: Chemical Compounds, PDP Commodity Grouping, Method Validation and Quality Control

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copy to the MPD laboratory liaison, shall be sent and approved/acknowledged by MPD, 

and that designation shall not be changed unless an e-mail communication is sent by the 

MPD Director reversing the previous approval.

5.18.3 Response To Failure To Meet Matrix Spike Criteria Range

If a spike analyte fails, even after re-injection/re-aliquoting, it can and should be reported, 

because the recovery may reflect normal random variation inherent to pesticide residue analysis. 

For high recoveries, this practice is defensible. For low recoveries, best professional judgment 

should be used, although if recovery is 0%, that analyte should be reported as unable to detect 

in samples. 

When a spiked pesticide recovery falls outside the range criteria, any one of the following 

options, or combination thereof, may be chosen by the TPM or designee. (See Attachment 6 –

Process Control and Spike Recovery Acceptability Flowchart.)

5.18.3.1 The original extract may be re-injected or re-aliquoted. If the spiked pesticide 

recovery falls within the range criteria, then the results from the re-injected extract shall be 

reported.

5.18.3.2 The sample set may be re-extracted from the frozen homogenate. If the spiked 

pesticide recovery falls within the range criteria, the rerun results shall be reported.

5.18.3.3 The original results may be reported with an explanation (e.g., recovery 

exceed 150% but all samples in the set are non-detects for that analyte; wrong mix spiked; 

spike spilled but process controls in samples are acceptable; control charts indicate a 

recurrent analyte/matrix; etc.). The TPM and QAO shall ensure that reported data is not 

compromised and the explanation shall be conveyed to headquarters (e.g., note in RDE, 

email message to MPD laboratory liaison and MPD Director).

5.18.3.4 Other options may be acceptable depending on the outcome of investigations 

and/or consultations with MPD. An explanation shall be conveyed to headquarters. 

5.18.4 Process Control Criteria
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Each laboratory shall decide whether to use the Absolute Range Criteria or the Statistically 

Calculated Range Criteria. A laboratory may choose different Range Criteria for different 

test types, but it is intended that a laboratory stay with the chosen criteria unless approved 

by the laboratory QAO.

5.18.4.1 Absolute Range

Each process control recovery shall fall between 50-150% for all detection systems used to 

calculate sample data.

5.18.4.2 Statistically Calculated Range

The mean recovery for a sample set’s process control shall be calculated. Each process 

control recovery shall fall within its acceptance recovery range, which is the mean recovery 

plus and minus three standard deviations.

5.18.5 Response To Failure To Meet Chosen Process Control Criteria Range

If a process control fails, even after re-injection/re-aliquoting/re-extraction, the results may be 

reported, based on best professional judgment. 

When a process control falls outside the chosen range criteria, any one of the following options, 

or combination thereof, may be chosen by the TPM or designee. (See Attachment 6 – Process 

Control and Spike Recovery Acceptability Flowchart.)

5.18.5.1 The original extract may be re-injected or re-aliquoted. If the process control 

recovery falls within the chosen range criteria, then the results from the re-injected or realiquoted extract shall be reported.

5.18.5.2 The sample may be re-extracted from the frozen homogenate. If the process 

control recovery falls within the chosen range criteria, the re-run results shall be reported.

5.18.5.3 The original results may be reported with an explanation (e.g., pipette error, 

the process control recovery exceeds 150% but all analytes in the sample are non-detects, 

etc.). The TPM and QAO shall ensure that reported data is not compromised and the 
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explanation shall be conveyed to headquarters (e.g., note in RDE, email message to MPD 

laboratory liaison and MPD Director).

5.18.5.4 Other options may be acceptable depending on the outcome of investigations 

and/or consultations with MPD. An explanation shall be conveyed to headquarters.

5.18.6 Evaluation of Recoveries

Laboratories shall use control charting or other appropriate statistical tools to evaluate recoveries 

on a set-to-set basis and monitor trends over time.

5.19 Proficiency Testing

5.19.1 PDP Proficiency Testing (PT) Program Overview

5.19.1.1 PDP Fiscal Year (FY) PT program schedules are posted to the PDP 

SharePoint site and are referenced in the applicable PDP Semi-Annual Program Plans.

5.19.1.2 General multi-residue method samples for fruit and vegetables will be 

supplied by the Food Analysis Performance Assessment Scheme (FAPAS) and the 

California Department of Food and Agriculture (CDFA).

5.19.1.3 Rounds for commodities other than fruit and vegetables (e.g., meat, milk and 

dairy products, fish, grains, nuts, etc.) shall be supplied by CDFA. Additionally, applicable 

FAPAS rounds may be scheduled.

5.19.1.4 PT samples received may be significantly larger than the analytical portion 

required by the laboratory for analysis. In cases where the PT sample is more than twice 

the analytical weight needed, the laboratory may subsample duplicate portions for 

extraction and analysis as described below, due to the uncertainty regarding homogeneity 

of samples. Sample results that meet the QC criteria shall be averaged for reporting.

5.19.1.5.1 Samples shall be mixed in the container they came in, taking care to not 

spill any sample prior to subsampling.

5.19.1.5.2 Two sub-samples shall be weighed out for extraction and extracted as 
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separate samples.

5.19.1.5.3 Each extract shall be analyzed as an individual sample.

5.19.2 Reporting PT Results

5.19.2.1 For FAPAS, lists of potentially spiked pesticides are available from the 

provider websites. Rounds issued by CDFA are designed to focus only on those compounds 

validated by the applicable laboratory(ies). For all rounds, participants shall only be 

evaluated for those residues validated by their laboratory and not declared as Marginal 

Performing Analytes. The report provided will clearly identify these pesticides. Reporting 

of the Marginal Performing Analytes shall be optional.

5.19.2.2 For FAPAS and CDFA, it is recognized that a laboratory may not have 

validated the commodity scheduled for that specific round. Standards used in routine 

analyses of assigned commodities should be used. Efforts will be made to provide a matrix 

blank for each round.

5.19.2.3 Report results according to provider instructions and requirements. 

Reporting to MPD via RDE is optional.

5.19.2.4 For FAPAS and CDFA, LOD/LOQ and recovery values reported may be 

values obtained from previous routine batches of the laboratory’s usual commodity(ies). 

5.19.2.5 Reports for each round shall be posted to the PDP SharePoint site within 10 

working days of receipt by MPD.

5.19.3 Laboratory Response

5.19.3.1 Upon receipt of PDP PT results, laboratories shall review results and initiate 

corrective actions when they are considered unacceptable by the PT scheme provider. 

5.19.3.2 Where FAPAS is the provider, z-scores whose absolute values are greater 

than 3 are unsatisfactory. 
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Note: FAPAS’ assigned/target value is the consensus value of the submitted results (with 

appropriate exclusions as noted in the FAPAS reports) and the target standard deviation is 

determined based on Horwitz.

5.19.3.3 For rounds provided by CDFA, unacceptable results shall be defined as those 

outside 50-150% recovery, or outside the statistically calculated range defined as ± 3xSD of 

the mean of last 20 data points of the laboratory’s spike recovery for the compound, or 

outside a range agreed upon with MPD. Unvalidated or Marginal Performing Analytes need 

not meet these criteria, but should be addressed in the PT section of the semi-annual QA 

report.

5.19.3.4 If any corrective actions are initiated due to the results, MPD shall be 

informed within 30 days. Refer to SOP PDP-ADMIN for notification details.

5.20 Measurement Uncertainty

Measurement uncertainty shall be determined on an annual (calendar year) basis by MPD. MPD 

will calculate each year’s value using 2x the standard deviation of program recovery data reported 

with each analytical data set. For example, during calendar year 2021, the mean program matrix 

spike recovery was 95% and the standard deviation was +/- 20.1%. Measurement uncertainty for 

2021 results would be expressed as “value ± 40.2%.” MPD will be responsible for communicating 

program measurement uncertainty values to data users.

MPD does not require individual PDP laboratories to report their measurement uncertainty along 

with sample results.
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Title: Chemical Compounds, PDP Commodity Grouping, Method Validation and Quality Control

Revision: 12 Replaces: 09/01/2021 Effective: 06/01/2023

Revised By: Sitra Abubeker Date

PDP Chemist, Monitoring Programs Division

1400 Independence Ave, SW

Washington, DC 20250

(202) 572-8175

Reviewed By: Sarvamangala Balachandra Date

Presiding Member of PDP Technical Advisory Group

California Department of Food and Agriculture

Center for Analytical Chemistry

3292 Meadowview Road

Sacramento, California 95832

(916) 228-6857

Approved By: Brenda Foos Date

MPD Director, Monitoring Programs Division

1400 Independence Ave, SW

Washington, DC 20250

(202) 572-8167

Original signed by Brenda Foos 5/30/2023

Original signed by Sarva Balachandra 5/30/2023

Original signed by Sitra Abubeker 5/30/2023
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Title: Chemical Compounds, PDP Commodity Grouping, Method Validation and Quality Control

Revision: 12 Replaces: 09/01/2021 Effective: 06/01/2023

Revision 12 June 2023 Monitoring Programs Division

• Changed USDA/AMS/MPD to MPD throughout the document

• Updated laboratory liaison to MPD laboratory liaison throughout the document

• Updated priority compound designation in section 5.1.2.2

• Updated priority requirements in section 5.1.2.3

• Renumbered sections 5.1.2.2.2 through 5.1.2.2.4

• Updated list of environmental contaminants for consistency in sections 5.1.2.2.3 and 5.2.1.2

• Updated logbook requirements for storage of analytical standards in section 5.2.3.3

• Added clarification to deviation requirements for standard recertification in sections 5.2.7.3

• Updated the detector profiles listed in section 5.2.9 and 5.13.1

• Updated section 5.4.1 for MPD notification if significant method changes occur 

• Added Method Validation Scenario table in section 5.6 for quick reference

• Added marker addition to attachment 2 upon request to section 5.7.2.2.

• Added Blackberries, Frozen Peaches and Tomatillos to section 5.9 and attachment 3. Added LOD can 

equal LOQ but is not a requirement in section 5.10.3.1

• Added request for MPD notification for increase in LOQs during method validation or changes in

status of previously validated priority 1 compounds in section 5.10.3.4.

• Updated LOD/LOD verification requirement when LOD does not equal LOQ in section 5.11.1

• Defined RDE in section 5.13.6

• Updated P&A collection requirements for each commodity in section 5.14

• Updated year in narrative for data package in section 5.15.5

• Added clarification to sample set definition 5.17.1

• Elaborated on method range, precision and accuracy data collection criteria in section 5.18.1.1

• Defined PC as process control in section 5.18.5.3

• Defined PT as proficiency testing in section 5.19.1

• Updated sections 5.19.2.2 and 5.19.2.4 to include CDFA proficiency testing

• Updated section 5.20 with the 2021 program measurement uncertainty

• Updated “Reviewed by” signature line

• Added the following compounds: amisulbrom, flazasulfuron, mandestrobin, 

mefentrifluconazole and tetraniliprole to attachment 2 

Revision 11 September 2021 Monitoring Programs Division

• Updated formatting of list of attachments in section 3

• Updated section 4 with weblinks, and organized references alphabetically and by order of appearance 

in CFR
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Title: Chemical Compounds, PDP Commodity Grouping, Method Validation and Quality Control

Revision: 12 Replaces: 09/01/2021 Effective: 06/01/2023

• Changed sections 5.1.2.1 and 5.1.2.2 to replace “posted to the PDP Extranet” with “distributed to 

analyzing laboratories”

• Updated section 5.1.2.1 with EPA acronym

• Added “as well as specific compounds identified as high priority by data users/stakeholders and 

reviewed by the MPD Director” to section 5.1.2.2.1

• Removed the word “highly” in section 5.1.2.2.2

• Updated list of environmental contaminants for consistency in sections 5.1.2.2.3 and 5.2.1.2

• Updated formatting of “see section 5.9” in section 5.6.3

• Updated section 5.9 to move Tomato Paste (TP) from the Single Commodities list to the Fruits and 

Vegetables list

• Added Frozen Blueberries to section 5.9

• Updated section 5.15.4 to now request the PDP-QC SOP version be included in cover memo

• Updated section 5.15.5.4 to include PDP-QC SOP version in example narrative for data package

• Changed USDA/AMS Extranet to PDP SharePoint site throughout the document

• Updated “revised by PDP Chemist” signature line

• Updated attachment 2 by adding the following compounds: 2,4-dichlorobenzophenone, 4,4-

dichlorobenzophenone, Demeton-S sulfoxide, Dicofol Total, Fluazifop-P-butyl, Hydroxy Acequinocyl, 

Imidacloprid Desnitro, Prothioconazole Desthio, Pyriofenone, S-Bioallethrin, and Valifenalate

• Updated attachment 3 to remove the Single Commodities reference for Tomato Paste (TP) in the PDP 

Commodity Group column

Revision 10 September 2020 Monitoring Programs Division

• Changed USDA/AMS to USDA/AMS/MPD throughout the document for clarification

• Added cross-referencing throughout the document

• Updated attachment 6 title in sections 3, 5.18.3 and 5.18.5

• Updated published date for the Federal Register and the Codex Alimentarius Commission web link 

and included a note indicating references were consulted in the preparation of the SOP in section 4

• Updated section 5.1.2.2.1 for priority 1 compound identification

• Updated section 5.2.1.2 with documenting standards that do not have a COA available

• Updated duplicate language in section 5.5.1

• Added section 5.6.2 to section 5.5.1.2 for cross reference

• Added reference to section 5.9 in sections 5.6.3, 5.6.4, 5.6.5 and 5.6.6

• Updated compounds being placed in marker groups per lab request in section 5.7.1.1

• Added collard greens to section 5.9

• Updated PDP Program years in example narrative for data package in section 5.15.5
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Title: Chemical Compounds, PDP Commodity Grouping, Method Validation and Quality Control

Revision: 12 Replaces: 09/01/2021 Effective: 06/01/2023

• Updated sections 5.16.2.3 and 5.18.1.3 for reporting analytes that do not meet method validation 

requirements

• Renumbered sections 5.19.1.4 and 5.19.1.5 to 5.19.1.3 and 5.19.1.4

• Updated measurement uncertainty results with 2018 survey data in section 5.20

• Changed PDP Technical Director reference to MPD Director in attachment 1

• Added the following compounds: afidopyropen, flutianil, isoxaben, pyrifluquinazon to 

attachment 2 

• Updated collard green code (GS) to code (GL) in attachment 3

• Added prunes to attachment 4 

Revision 9 September 2019 Monitoring Programs Division

• Updated Attachment 2 by adding the following compounds: Benzoyindiflupyr, cyclaniliprole, 

ethaboxam, fenpicoxamid, isopyrazam, kinoprene, mancozeb, oxathiapiprolin, pydiflumetofen, thiram 

and tridemorph

• Updated CAS# for azinphos methyl oxygen analog in Attachment 2

• Updated Attachment 3 with new commodities: basil, mustard greens and radishes. Added commodity 

codes for dried garbanzo beans, canned cranberry, canned peas, canned sweet corn, frozen spinach and 

frozen sweet corn. Changed vegetable peas to frozen peas and fresh sweet corn code (CS) to code (CB)

• Updated Attachment 4 with new commodities: basil, mustard greens and radishes

• Updated Attachment 4 heading in section 3

• Added reference to U.S.FDA, Approximate pH of Foods and Food products in section 4

• Updated U.S. EPA, Pesticide Use Index, U.S. FDA, Pesticide Analytical Manual Volume 1 (PAM) 3rd

Edition, Chapter 2 and Codex, Pesticide Residues in Food and Feed web links in section 4

• Updated the webpage for EPA Repository in section 5.2.1.1

• Added clarification to standard checking in section 5.2.6.1 

• Rearranged commodities in alphabetical order, changed peas (PS) to frozen peas (PS), changed fresh 

sweet corn code (CS) to code (CB), added basil, canned cranberries, canned peas, canned spinach, 
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canned sweet corn, cherries, dried garbanzo beans, frozen raspberries, frozen spinach, frozen 

strawberries, frozen sweet corn, frozen winter squash, kiwi, mustard greens and radishes to section 5.9.

• Updated reference to Attachment 4 in section 5.9.2

• Changed MP to USDA/AMS in section 5.11.4

• In section 5.15.4 removed the requirement to send a hard copy of the method evaluation to 

USDA/AMS by mail

• Changed PDP Technical Director to MPD Director throughout the document

• Changed USDA/AMS liaison and USDA/AMS liaison chemist to USDA/AMS laboratory liaison 

throughout the document

• Added USDA/AMS laboratory liaison to section 5.16.2.1

• Clarified section 5.17.4.3 by adding reference to section 5.18.2, matrix spike criteria

Revision 8 February 2018 Monitoring Programs Division

• Updated the heading for section 5.11 throughout the document

• Updated guidance to section 5.11 for LOQ verification

• In section 5.13.2 replaced “single PDP analyte” with “compound being validated”

• Updated Attachment 2 by adding the following compounds: aspon, aclonifen, anilofos, 

atraton, beflubutamid, bioallethrin, bromophos ethyl, chlordimeform, chlorthiophos, 

desmetryn, dichlofenthion, dimepiperate, dipropetryn, ditalimfos, diphacinone, dithiopyr,

dioxacarb, etrimfos, famphur, fluensulfone, flazasulfuron, flucythrinate, fluorodifen, 

iprobenfos, isoprothiolane, mephosfolan, methacrifos, mefenacet, simetryn, prodiamine, 

pretilachlor, pyraclofos, pyridaphenthion, terbutryn, trichloronate

• Added commodity codes for canned tomatoes, canned garbanzo beans, canned peaches, dried 

plum/prunes and honey to section 5.9

• Updated attachment 3 with new commodities: canned peaches and dried plum/prunes

 

Revision 7 February 2017 Monitoring Programs Division

• Updated Attachment 2 by adding the following compounds: 1,3 dichloropropene, 2,6 DIPN, 5-(4-

chlorophenyl) oxazole-2-propionic acid (CPOPA), acetamide, allidochlor, amicarbazone, aminopyralid, 

asulam, barban, chlorpyrifos methyl O-analog, cloquintocet methyl, cloquintocet mexyl, cumyluron. 

cyclanilide, dinocap, ethephon, flumetralin, flupyradifurone, glufosinate, hexaflumuron, isofetamid, 

kasugamycin, melamine, merphos, metrafenone, niclosamide, oxythioquinox, perthane, piperalin, 
United States Department of Agriculture

Agricultural Marketing Service, Science & Technology

Pesticide Data Program

SOP No.: PDP-QC Page 44 of 47

Title: Chemical Compounds, PDP Commodity Grouping, Method Validation and Quality Control

Revision: 12 Replaces: 09/01/2021 Effective: 06/01/2023

prohexadione calcium, propoxycarbazone, proquinazid, prothioconazole, quinchlorac, thidiazuron, 

thiencarbazone methyl

• Removed oxytetracycline from Attachment 2

• Added commodity codes for canned olives, kale, canned pineapple to section 5.9

• Updated section 4: link to Codex Alimentarius Commission, Pesticide Residues in Food and Feed

• Updated attachment 3 with new commodities: canned pineapples and canned olives

• Updated attachment 4 with new commodity: canned olives

Revision 6 February 2016 Monitoring Programs Division

• Updated Attachment 2 by adding the following compounds: acequinocyl, ametoctradin, benalaxyl, 

benazolin, BHC-delta, BHC-epsilon, bifenox, carbophenothion methyl, chlorobenzilate, cloransulam 

methyl, cyantraniliprole, cyflufenamid, cyflumetofen, cyprosulfamide, dichlormid, diclosulam, 

diethofencarb, diniconazole, EPN, ethiofencarb sulfone, ethiofencarb sulfoxide, ethiprole, ethylan, 

etofenprox, fenoxycarb, fenpropidin, fenpyrazamine, fenthion sulfone, fenthion sulfoxide, fluazifop, 

flufenpyr ethyl, flumiclorac pentyl, fluopyram, fluthiacet methyl, fomesafen, furalaxyl, heptenophos, 

imazosulfuron, ipconazole, isocarbophos, isofenphos methyl, isoprocarb, isoproturon, isoxadifen ethyl, 

mecarbam, mefenpyr diethyl, mesotrione, metolcarb, monolinuron, nitrofen, penflufen, phorate OA 

sulfone, phorate OA sulfoxide, picoxystrobin, profluralin, profoxydim, pyraflufen, pyroxasulfone, 

quizalofop, rotenone, sedaxane, sulfallate, sulfoxaflor, terbufos OA sulfone, terbufos sulfoxide, 

thionazin, tolfenpyrad, topramezone, and tricyclazole
United States Department of Agriculture

Agricultural Marketing Service, Science & Technology

Pesticide Data Program

SOP No.: PDP-QC Page 45 of 47

Title: Chemical Compounds, PDP Commodity Grouping, Method Validation and Quality Control

Revision: 12 Replaces: 09/01/2021 Effective: 06/01/2023

• Included additional matrix spike language to sections 5.17.4 and 5.18.2

• Removed references to AOAC PTs in section 5.19

Revision 5 August 2014 Monitoring Programs Division

• Updated references to USDA/AMS throughout document

• Updated prioritization protocols in sections 5.1.2.1, 5.1.2.2.2, 5.1.2.2.3, and 5.1.2.2.4

• Changed standard checking requirement to 15% RPD in sections 5.2.6, 5.2.6.2, 5.2.7.2.1, and 5.2.7.2.2

• Combined laboratory Letter of Intent requirements into section 5.15.3

• Updated USDA/AMS address in section 5.15.4

• Updated USDA/AMS Letter of Intent procedures in section 5.16.1

Revision 4 July 2013 Monitoring Programs Division

• Updated references to USDA/AMS throughout document

• Added commodity codes for avocado, catfish, dairy-based infant formula, raspberries, salmon, and soybased infant formula to section 5.9

• Added procedures for subsampling PT samples to section 5.19.1.5

• Updated Attachment 2 by adding the following compounds: acrinathrin, AMPA, aviglycine HCl, 

bromopropylate, bupirimate, butocarboxim, butocarboxim sulfone, butocarboxim sulfoxide, 

chlorsulfuron, chlozolinate, clethodim 5 hydroxy sulfone, clethodim sulfone, clethodim sulfoxide, 

clofencet, crotoxyphos, crufomate, demeton-S, demeton-S sulfone, dichlofluanid, DMST,fenbutatin 

oxide, fenchlorphos, fenpropimorph, fensulfothion, fenthion o-analog, fipronil sulfone, 

fluquinconazole, flusilazole, flutriafol, fluxapyroxad, glyphosate, haloxyfop, iodosulfuron methyl, 

lenacil, lufenuron, mesosulfuron methyl, metaflumizole, methiocarb sulfone, methiocarb sulfoxide, 

oxytetracyline, paclobutrazol, penconazole, pencyuron, penthiopyrad, phoxim, pirimicarb desmethyl, 

primisulfuron, propaquizafop, prosulfuron, prothiofos, pyrazaophos, quizalofop ethyl, sethoxydim 
United States Department of Agriculture

Agricultural Marketing Service, Science & Technology

Pesticide Data Program

SOP No.: PDP-QC Page 46 of 47

Title: Chemical Compounds, PDP Commodity Grouping, Method Validation and Quality Control

Revision: 12 Replaces: 09/01/2021 Effective: 06/01/2023

sulfoxide, spiroxamine, sulfosulfuron, tebufenpyrad, teflubenzuron, terbuthylazine, thifensulfuron 

methyl, thymol, toxaphene, and tribenuron methyl 

• Updated Attachments 3 and 4 for the following commodities: avocado, catfish, infant formula (dairybased and soy based), raspberries, and salmon

Revision 3 March 2012 Monitoring Programs Division

• Updated prioritization rationale in section 5.1.2

• Added exemption for CoA and current expiration date for revoked compounds to section 5.2.1.2

• Defined extraction/detection system in section 5.4.3

• Clarified process control compound requirements in section 5.8

• Combined PDP Commodity Groupings in section 5.9

• Added guidance for LOD establishment for zero noise instruments in section 5.10.2.2

• Changed multi-peak compound LOD requirements in section 5.10.2.5

• Changed LOD verification requirements in section 5.11.4

• Specified PT samples larger than routine analytical samples may be run in duplicate in section 5.19.1.5

• Clarified what constitutes unacceptable PT scores in section 5.19.3.2

• Updated Attachment 2 by adding the following compounds: 2,4-DMPF, DEET, Dialofos, Dioxathion, 

Endothall, Indaziflam, Leptophos o-analog, Metconazole, Quinalphos, Saflufencil, Triazophos

Revision 2 July 2011 Monitoring Programs Division

• Updated the entire SOP with the new program’s name Monitoring Programs Division or MP instead of 

MPO

• Updated the Reference list.

• Removed the word “Note” in sections 5.2.1.2; 5.6.2.3; 5.6.4; 5.10.2; 5.20 leaving the paragraphs as 

instructions

• Updated section 5.2.7 by renumbering the subsections

• Added new commodities (Baby Foods, Papaya, Tangerines, Cherry Tomatoes, Snap Peas, Canned Beets) 

to 5.9

• Updated sections 5.15.5.3, 5.16.2.5 about approving MPAs

• Added the E code in section 5.17.8

• Updated requirements for section 5.18.2 by eliminating subsection 5.18.2.1

• Updated sections 5.18.2.2.1, 5.18.2.2.2 about MPAs (re)designation, replacing the letter of deviation with 

e-mail communication

• Updated section 5.18.2.2.2 by replacing the letter of deviation requirement with an e-mail communication

• Updated sections 5.19.1 and 5.19.2, by replacing “Ultra/GLEC” with “Ultra” 

• Updated section 5.19.3.1 with new FAPAS requirements regarding z-scores
United States Department of Agriculture

Agricultural Marketing Service, Science & Technology

Pesticide Data Program

SOP No.: PDP-QC Page 47 of 47

Title: Chemical Compounds, PDP Commodity Grouping, Method Validation and Quality Control

Revision: 12 Replaces: 09/01/2021 Effective: 06/01/2023

• In section 5.19.1.3 replaced “collected by GLEC” with “provided by MP”

• Updated Attachment 2 by adding a Group 4, Benzothiazoles/triazolones, to ‘PDP Compound Groups for 

Fruit and Vegetables’ list

• Updated Attachment 2 by adding the following compounds: Fosthiazate, Iprovalicarb, Rimsulfuron, 

Trifloxysulfuron, Uniconazole to PDP Pesticides Codes list

• Updated Attachment 3, 4 with new commodities: Baby Foods, Papaya, Tangerines, Cherry Tomatoes, 

Snap Peas, Canned Beets

Revision 1 July 2010 Monitoring Programs Office

• Renumbered the entire SOP replacing the sections’ letters with numbers.

• Redefined Priority 1-4 compounds.

• Updated section 5.2.8 for Working Dilutions/Mixed Standards.

• Changed and updated section 5.5 Method Validation Evaluation Guidelines.

• Changed and updated section 5.6 Method Validation Scenarios.

• Updated section 5.7 Marker Pesticides to remove mandatory markers.

• Updated section 5.9 PDP Commodity Groupings.

• Removed section 5.12 LOD Check.

• Added section 5.13.6 Method Range Extension.

• Updated section 5.15.3 as part of Method Evaluation Reporting.

• Removed section 5.16.e.4

• Removed section 5.18.d.1.b

• Updated section 5.19.c (now 5.18.2) Matrix Spike Criteria.

• Updated section 5.19.e (now 5.18.3) Response to Failure To Meet Matrix Spike Criteria Range.

• Updated section 5.19.d (now 5.18.5) Response to Failure To Meet Chosen Process Control Criteria 

Range.

• Updated Attachment 1.

• Updated Attachment 2, by adding the following new compounds: Avermectin B1, Bensulide oxygen 

analog, Cyhalofop butyl, Dimethipin, Disulfoton oxygen analog, Disulfoton oxygen analog sulfone, 

Disulfoton oxygen analog sulfoxide, Eprinomectin, Fenobucarb (BPMC), Flubendiamine, Flufenoxuron, 

Fluopicolide, Imidacloprid urea, Mandipropamid, Metaldehyde, Milbemectin, Pinoxaden, Promecarb, 

Prothioconazole, Pyrasulfotole, Pyridalyl, Tepraloxydim.

• Updated Attachments 3, 4 and 5.
Method Evaluation Flowchart

P

Major Extraction

Change? (5.6.2.1)

Major Post Extraction Sample 

Prep. Change? (5.6.2.2)

Instrument Change? 

(5.6.2.3)

Method Change? (5.6.2)

Consult the laboratory Technical Program Manager (TPM) and 

Quality Assurance Officer. Apply the appropriate module(s) to 

each segment of the method , for affected compounds, as 

needed. If local agreement cannot be reached, contact the MPD 

Director. 

Adding a New Commodity 

Group? (5.6.3)

5.11 Verify LODs/LOQs

5.13 Method Range (markers only)

5.14 Precision & Accuracy

5.15 Method Evaluation Reporting

Adding a Raw Agricultural 

Commodity or Processed 

Commodity to an Existing 

Group? (5.6.4)

5.11 Verify LODs/LOQs

5.14 Precision & Accuracy (2 pts)

5.15 Method Evaluation Reporting

Adding a New Pesticide, 

Related to the Marker 

Compound Groups, to an 

Existing Commodity Group? 

(5.6.5)

5.10 Establish LODs/LOQs

5.11 Verify LODs/LOQs

5.14 Precision & Accuracy

5.15 Method Evaluation Reporting

Adding a New Pesticide, NOT 

Related to the Marker 

Compound Groups, to an 

Existing Commodity Group? 

(5.6.6)

5.10 Establish LODs/LOQs

5.11 Verify LODs/LOQs

5.13 Method Range (for those that will 

become markers)

5.14 Precision & Accuracy

5.15 Method Evaluation Reporting

No

No

Yes

Yes

Yes

Yes

Yes

Yes

Minor Change? 

(5.6.2.4)

Yes

5.10 Establish LODs/LOQs

5.11 Verify LODs/LOQs

5.13 Method Range (markers only)

5.14 Precision & Accuracy

5.15 Method Evaluation Reporting

5.11 Verify LODs/LOQs

5.13 Method Range (markers only)

5.14 Precision & Accuracy

5.15 Method Evaluation Reporting

5.10 Establish LODs/LOQs

5.11 Verify LODs/LOQs

5.13 Method Range (markers only)

5.14 Precision & Accuracy

5.15 Method Evaluation Reporting

Yes

New LOD? 

Yes

5.10 Establish LODs/LOQs

5.11 Verify LOD/LOQs

5.15 Method Evaluation Reporting

Yes

No

New Method? (5.6.1)

No

Yes 5.10 Establish LODs/LOQs

5.11 Verify LODs/LOQs

5.13 Method Range (markers only)

5.14 Precision & Accuracy

5.15 Method Evaluation Reporting

No

Yes

USDA/AMS Science Technology

Monitoring Programs Division

PDP QC Attachment 1

Revision 12 - Effective June 1, 2023
PDP Compound Groups for Fruit and Vegetables

Group Description

1 Phthalimides, conazoles and metabolites, carbamaldehydes, phenyl pyrroles, methoxy-acetamides, and neonicotinyls

2 Cyano/nitrile group(s) attached to double bond

3 Halogenated aromatics and chlorinated cyclics/cyclodienes

4 Benzothiazoles/triazolones

7 Dinitroanilines

8 Pyrethroids and metabolites and synergists

9 Triazines

11 Organophosphates and metabolites

14 Carbamates, thiocarbamates and metabolites

16 Uracils/ureas, imidazolinones, diacylhydrazines, and sulfonyl ureas

17 Nitrogenous heterocyclics

20 Phenoxy acids, ethanesulfonic acids (ESA), and oxanilic acids(OA) 

21 Oxyhydrocarbons

22 Strobilurins

27 Tetronic acids

28 Cyclohexenone oxime

29 Macrocyclic lactones

99 Single

Note: Missing group numbers are attributed to the consolidation of groups. For example, Group 15, Thiocarbamates, was consolidated into 

Group 14, Carbamates.

USDA/AMS Science and Technology

Monitoring Programs Division 1

PDP QC Attachment 2

Revision 12 - Effective June 1, 2023
PDP Pesticide Codes and Multi-residue Compound Groupings for Fruit and Vegetables

Compound Name CAS# Molecular Formula Chemical Family Group Pesticide 

Code

1-naphthol 90-15-3 C10H8O carbamate metabolite 14 382

1,2,4-triazole 288-88-0 C2H3N3 triazole metabolite 1 A68

1,3-dichloropropene 542-75-6 C3H4Cl2 fumigant nematicide 251

2,4-DB 94-82-6 C10H10Cl2O3 phenoxy acid 20 317

2,4-D 94-75-7 C8H6Cl2O3 phenoxy acid 20 026

2,4-dimethylphenyl formamide (DMPF) 60397-77-5 C9H11NO amidine 2 AGR

2,4,5-T 93-76-5 C8H5Cl3O3 phenoxy acid 20 312

2,6-DIPN 24157-81-1 C16H20 substituted naphthalene 99 AFZ

3-hydroxycarbofuran 16655-82-6 C12H15NO4 carbamate metabolite 14 512

4-dimethylaminosulphotoluidide (DMST); 

tolylfluanid metabolite 66840-71-9 C9H14N2O2S phenylsulfamidemetabolite 1 AJU

5-hydroxythiabendazole 948-71-0 C10H8N3OS carbamate 1 B28

Abamectin 71751-41-2 C48H72O14 + C47H70O14 avermectin (macrocyclic lactone) 29 948

Acephate 30560-19-1 C4H10NO3PS phosphoramidothioic acid 11 204

Acequinocyl 57960-19-7 C24H32O4 unclassified acaricides 99 AKS

Acetamide 60-35-5 C2H5NO amide 1 AAT

Acetamiprid 160430-64-8 C10H11ClN4 neonicotinyls 1 B80

Acetochlor 34256-82-1 C14H20ClNO2 chloroacetanilide 1 807

Acetochlor ethanesulfonic acid 187022-11-3 C8H21NO5S chloroacetanilide metabolite 20 ABN

Acetochlor oxanilic acid 194992-44-4 C14H19NO4 chloroacetanilide metabolite 20 ABO

Acibenzolar-S-methyl 135158-54-2 C8H6N2OS2 thiadiazole 1 B51

Acifluorfen 50594-66-6 C14H21NO5S diphenyl ether 3 727

Aclonifen 74070-46-5 C12H9ClN2O3 nitrophenyl ether 3 D58

Acrinathrin 103833-18-7 C26H21F6NO5 pyrethroid 8 A03

Afidopyropen 915972-17-7 C33H39NO9 Nitrogenous heterocyclics 17 F87

Alachlor 15972-60-80 C14H20ClNO2 acetamide 1 227

Alachlor ethanesulfonic acid 142363-53-9 C8H21NO5S chloroacetanilide metabolite 20 ABP

Alachlor oxanilic acid 171262-17-2 C14H19NO4 chloroacetanilide metabolite 20 ABQ

Aldicarb 116-06-3 C7H14N2O2S carbamate 14 167

USDA/AMS Sceince and Technology 2

PDP QC Attachment 2

Revision 12 - Effective June 1, 2023
PDP Pesticide Codes and Multi-residue Compound Groupings for Fruit and Vegetables

Compound Name CAS# Molecular Formula Chemical Family Group Pesticide 

Code

Aldicarb sulfone 1646-88-4 C7H14N2O4S carbamate 14 168

Aldicarb sulfoxide 1646-87-3 C7H14N2O3S carbamate 14 169

Aldrin 309-00-2 C12H8Cl6 cyclodiene 3 001

Allethrin 584-79-2 C19H26O3 pyrethroid 8 002

Allidochlor 93-71-0 C8H12ClNO amide 1 768

Ametoctradin 865318-97-4 C15H25N5 triazolopyrimidine fungicides 1 AKC

Ametryn 834-12-8 C9H17N5S triazine 9 156

Amicarbazone 129909-90-6 C10H19N5O2 triazolone 4 AGK

Aminomethylphosphonic acid (AMPA) 1066-51-9 CH6NO3P organophosphate metabolite 99 957

Aminopyralid 150114-71-9 C6H4Cl2N2O2 pyradine 20 AGO

Amitraz 33089-61-1 C19H23N3 amidine 2 233

Amisulbrom 348635-87-0 C13H13BrFN5O4S2 sulfonamide/bromoindoles 14 AMN

Anilazine 101-05-3 C9H5Cl3N4 triazine 9 033

Anilofos 64249-01-0 C13H19ClNO3PS2 organophosphate 11 D62

Aspon 3244-90-4 C12H28O5P2S2 organophosphate 11 816

Asulam 3337-71-1 C8H10N2O4S sulfonamide 14 ANG

Atraton 1610-17-9 C9H17N5O methoxytriazine 9 D64

Atrazine 1912-24-9 C8H14ClN5 triazine 9 305

Avermectin B1 71751-41-2

C48H72O14 (avermectin B1a) + 

C47H70O14 (avermectin B1b) macrocyclic lactone 29 AHQ

Aviglycine HCl 55720-26-8 C6H12N2O3 ethylene inhibitors 99 AKT

Azinphos ethyl 2642-71-9 C12H16N3O3PS2 organophosphate 11 547

Azinphos methyl 86-50-0 C10H12N3O3PS2 benzotriazine 11 042

Azinphos methyl oxygen analog 961-22-8 C10H12N3O4PS oxon 11 769

Azoxystrobin 997888-88-8 C22H17N3O5 strobilurin 22 B48

Barban 101-27-9 C11H9Cl2NO2 carbanilate 14 716

USDA/AMS Sceince and Technology 3

PDP QC Attachment 2

Revision 12 - Effective June 1, 2023
PDP Pesticide Codes and Multi-residue Compound Groupings for Fruit and Vegetables

Compound Name CAS# Molecular Formula Chemical Family Group Pesticide 

Code

Benalaxyl 71626-11-4 C20H23NO3 anilide fungicides 1 B45

Benazolin 3813-05-6 C9H6ClNO3S benzothiazole herbicides 4 832

Bendiocarb 22781-23-3 C11H13NO4 carbamate 14 658

Beflubutamid 113614-08-7 C18H17F4NO2 amide 1 D69

Benfluralin 1861-40-1 C13H16F3N3O4 dinitroaniline 7 191

Benomyl 17804-35-2 C14H18N4O3 benzimidazole 14 192

Benoxacor 98730-04-2 C11H11Cl2NO2 benzoxazine 1 A05

Bensulfuron methyl 83055-99-6 C16H18N4O7S sulfonyl urea 16 ABR

Bensulide 741-58-2 C14H24NO4PS3 organophosphate 11 239

Bensulide oxygen analog 20243-81-6 C14H24NO4PS3 organophosphate 11 740

Bentazon 25057-89-0 C10H12N2O3S thiadiazinone dioxide 17 758

Benthiavalicarb-isopropyl 177406-68-7 C15H18FN3O3S benzothiazole 4 AGP

Benzovindiflupyr 1072957-71-1 C18H15Cl2F2N3O pyrazole 1 F53

BHC alpha 319-84-6 C6H6Cl6 hexane ring 3 903

BHC beta 319-85-7 C6H6Cl6 hexane ring 3 904

BHC, delta 319-86-8 C6H6Cl6 hexane ring 3 905

BHC, epsilon 6108-10-7 C6H6Cl6 hexane ring 3 ALH

Bifenazate 149877-41-8 C17H20N2O3 hydrazine carboxylate 14 B82

Bifenox 42576-02-3 C14H9Cl2NO5 nirophenyl ether herbicides 3 728

Bifenthrin 82657-04-3 C23H22ClF3O2 pyrethroid 8 930

Bioallethrin 260359-57-7 C19H26O3 pyrethroid 8 ANP

Bitertanol 55179-31-2 C20H23N3O2 triazole 1 850

Boscalid 188425-85-6 C18H12Cl2N2O anilide/pyridine 1 B75

Bromacil 314-40-9 C9H13BrN2O2 uracil 16 153

Bromophos ethyl 4824-78-6 C8H8BrCl2O3PS organophosphate 11 602

Bromopropylate 18181-80-1 C17H16Br2O3 bridged diphenyl 3 523

Bromoxynil 1689-84-5 C7H3Br2NO phenol 20 729

Bromuconazole-46 NA[2] C13H12BrCl2N3O conazole 1 ADU

USDA/AMS Sceince and Technology 4

PDP QC Attachment 2

Revision 12 - Effective June 1, 2023
PDP Pesticide Codes and Multi-residue Compound Groupings for Fruit and Vegetables

Compound Name CAS# Molecular Formula Chemical Family Group Pesticide 

Code

Bromuconazole-47 NA[2] C13H12BrCl2N3O conazole 1 ADV

Bupirimate 41483-43-6 C13H24N4O3S pyrimidine 17 or 3 872

Buprofezin 69327-76-0 C16H23N3OS thiadiazinone 17 B52

Butachlor 23184-66-9 C17H26ClNO2 chloroacetanilide 1 806

Butocarboxim 34681-10-2 C7H14N2O2S oxime carbamate 14 857

Butocarboxim sulfone NA[2] C7H14N2O4S oxime carbamate metabolite 14 AKN

Butocarboxim sulfoxide 34681-24-8 C7H14N2O3S oxime carbamate metabolite 14 AKO

Butylate 2008-41-5 C11H23NOS thiocarbamate 14 783

Cadusafos 95465-99-9 C10HOPS2 phosphorodithionate 11 953

Captafol 2939-80-2 C10H9Cl4NO2S phthalimide 1 174

Captan 133-06-2 C9H8Cl3NO2S phthalimide 1 011

Carbaryl 63-25-2 C12H11NO2 carbamate 14 102

Carbendazim 10605-21-7 C9H9N3O2 benzimidazole 14 666

Carbofuran 1563-66-2 C12H15NO3 carbamate 14 180

Carbophenothion 786-19-6 C11H16ClO2PS3 organophosphate 11 202

Carbophenothion methyl 953-17-3 C9H12ClO2PS3 organophosphate 11 AGZ

Carboxin 5234-68-4 C12H13NO2S carboxamide 1 210

Carfentrazone ethyl 128639-02-1 C15H14Cl2F3N3O3 fluorophenyl triazole 4 B21

Chloramben 133-90-4 C7H5Cl2NO2 benzoic acid 20 952

Chlorantraniliprole 500008-45-7 C18H14BrCl2N5O2 diamide; pyrazole 1 AGW

Chlordane cis 5103-71-9 C10H6Cl8 cyclodiene 3 173

Chlordane trans 5103-74-2 C10H6Cl8 cyclodiene 3 172

Chlordimeform 6164-98-3 C10H13ClN2 formamidine 3 278

Chlorethoxyfos 54593-83-8 C6H11Cl4O3PS phosphorothioate 11 A15

Chlorfenapyr 122453-73-0 C15H11BrClF3N2O pyrrole 1 B13

Chlorfenvinphos total 470-90-6 C12H14Cl3O4P organophosphate 11 AAK

Chlorimuron ethyl 90982-32-4 C15H15ClN4O6S sulfonyl urea 16 717

Chlorobenzilate 510-15-6 C16H14Cl2O3 bridged dipehnyl 3 015

USDA/AMS Sceince and Technology 5

PDP QC Attachment 2

Revision 12 - Effective June 1, 2023
PDP Pesticide Codes and Multi-residue Compound Groupings for Fruit and Vegetables

Compound Name CAS# Molecular Formula Chemical Family Group Pesticide 

Code

Chloroneb 2675-77-6 C8H8Cl2O2 chlorobenzene 3 196

Chlorothalonil 1897-45-6 C8Cl4N2 phthalimide 2 164

Chlorpropham 101-21-3 C10H12ClNO2 carbamate 14 114

Chlorpyrifos 2921-88-2 C9H11Cl3NO3PS phosphorothionic acid 11 160

Chlorpyrifos methyl 5598-13-0 C7H7Cl3NO3PS phosphorothionic 11 235

Chlorpyrifos methyl O-analog 5598-52-7 C7H7Cl3NO4P oxon 11 AAZ

Chlorpyrifos oxygen analog 5598-15-2 C9H11Cl3NO4P oxon 11 772

Chlorsulfuron 64902-72-3 C12H12ClN5O4S triazinylsulfonyl urea 16 718

Chlorthiophos 60238-56-4 C11H15Cl2O3PS2 organophosphate 3 545

Chlozolinate 84332-86-5 C13H11Cl2NO5 dichlorophenyl dicarboxamide; oxazole 1 AJS

Clethodim 99129-21-2 C17H26ClNO3S cyclohexene oxime 28 AER

Clethodim 5-hydroxy sulfone 111031-11-9 C17H26ClNO6S cyclohexene oxime metabolite 28 AJM

Clethodim sulfone 111031-17-5 C17H26ClNO5S cyclohexene oxime metabolite 28 AJN

Clethodim sulfoxide 111031-14-2 C17H26ClNO4S cyclohexene oxime metabolite 28 AJO

Clodinafop propargyl 105512-06-9 C17H13ClFNO4 aryloxyphenoxypropionic acid 20 B38

Clofencet 129025-54-3 C13H11ClN2O3 unclassified 99 AET

Clofentezine 74115-24-5 C14H8Cl2N4 tetrazine 99 699

Clomazone 81777-89-1 C12H14ClNO2 pyridazone 17 719

Clopyralid 1702-17-6 C6H3Cl2NO2 pyridinecarboxylic acid 20 B46

Cloquintocet methyl 99607-70-2 C18H22ClNO3 herbicide safener 1 AKE

Cloquintocet mexyl 99607-70-2 C18H22ClNO3 herbicide safener 1 B39

Cloransulam methyl 147150-35-4 C15H13ClFN5O5S triazolopyrimidine herbicides 1 ALP

Clothianidin 210880-92-5 C6H8ClN5O2S neonicotinyl 1 AEP

Coumaphos 56-72-4 C14H16ClO5PS phosphorothioate 11 124

Coumaphos oxygen analog 321-54-0 C14H16ClO6P oxon 11 614

CPOPA (5-(4-Chlorophenyl)oxazole-2-

propionic Acid) 23464-95-1 C12H10ClNO3 propionic acid 20 ALQ

Crotoxyphos 7700-17-6 C14H19O6P organophosphate 11 267

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PDP Pesticide Codes and Multi-residue Compound Groupings for Fruit and Vegetables

Compound Name CAS# Molecular Formula Chemical Family Group Pesticide 

Code

Crufomate 299-86-5 C12H19ClNO3P phosphoramidate 11 667

Cumyluron 99485-76-4 C17H19ClN2O Urea 16 ANJ

Cyanazine 21725-46-2 C9H13ClN6 triazine 9 228

Cyantraniliprole 736994-63-1 C19H14BrClN6O2 pyrazole 1 AMB

Cyazofamid 120116-88-3 C13H13ClN4O2S imidazole 1 AGA

Cyclanilide 113136-77-9 C11H9Cl2NO3 unclassified plant growth regulator 1 A81

Cyclaniliprole 1031756-98-5 C21H17Br2Cl2N5O2 pyrazole 1 F40

Cycloate 1134-23-2 C11H21NOS thiocarbamate 14 232

Cyflufenamid 180409-60-3 C20H17F5N2O2 amide 1 AKU

Cyflumetofen 400882-07-7 C24H24F3NO4 bridged dipehnyl 3 AMC

Cyfluthrin 68359-37-5 C22H18Cl2FNO3 pyrethroid 8 781

Cyhalofop butyl 122008-85-9 C20H20FNO4 aryloxyphenoxypropionic herbicide 17 B59

Cyhalothrin (lambda) 91465-08-6 C23H19ClF3NO3 pyrethroid 8 AEM

Cyhalothrin (lambda epimer R157836) 68085-85-8 C23H19ClF3NO3 pyrethroid 8 AEN

Cyhalothrin total (L-cyhalothrin + R157836 epim 68085-85-8 C23H19ClF3NO3 pyrethroid 8 AEL

Cymoxanil 57966-95-7 C7H10N4O3 cyanoacetamide 2 877

Cypermethrin 52315-07-8 C22H19Cl2NO3 pyrethroid 8 597

Cyphenothrin 39515-40-7 C24H25NO3 pyrethroid 8 ADH

Cyproconazole 94361-06-5 C15H18ClN3O conazole 1 A22

Cyprodinil 121552-61-2 C14H15N3 anilinopyrimidine 17 B22

Cyprosulfamide 221667-31-8 C18H18N2O5S herbicide safeners 1 AMD

Cyromazine 66215-27-8 C6H10N6 triazine 9 255

DCPA 1861-32-1 C10H6Cl4O4 phthalic acid 3 134

DCPA mono acid 887-54-7 C9H4Cl4O4 dicarboxylic acid 20 ABV

DDD o,p' 53-19-0 C14H10Cl4 bridged biphenyl 3 909

DDD p,p' 72-54-8 C14H10Cl4 bridged biphenyl 3 908

DDE o,p' 3424-82-6 C14H8Cl4 bridged biphenyl 3 911

DDE p,p' 72-55-9 C14H8Cl4 bridged biphenyl 3 910

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PDP Pesticide Codes and Multi-residue Compound Groupings for Fruit and Vegetables

Compound Name CAS# Molecular Formula Chemical Family Group Pesticide 

Code

DDT o,p' 789-02-6 C14H9Cl5 bridged biphenyl 3 907

DDT p,p' 50-29-3 C14H9Cl5 bridged biphenyl 3 906

DEET (N,N-diethyl-m-toluamide) 134-62-3 C12H17NO amide 2 PBS

DEF (Tribufos) 78-48-8 C12H27OPS3 organophosphate 11 217

Deltamethrin (includes parent Tralomethrin) 52918-63-5 C22H19Br2NO3 pyrethroid 8 612

Demeton 8065-48-3 C8H19O3PS2 phosphorothioate 11 023

Demeton-S 126-75-0 C8H19O3PS2 organothiophosphate 11 558

Demeton-S sulfone 2496-91-5 C8H19O5PS2 organothiophosphate metabolite 11 226

Demeton-S sulfoxide 2496-92-6 C8H19O4PS2 organothiophosphate metabolite 11 A24

Desethyl atrazine 6190-65-4 C6H10ClN5 triazine metabolite 9 964

Desethyl-desisopropyl atrazine 3397-62-4 C3H4ClN5 triazine metabolite 9 784

Desisopropyl atrazine 1007-28-9 C5H8ClN5 triazine metabolite 9 785

Desmedipham 13684-56-5 C16H16N2O4 carbamate 14 786

Desmetryn 1014-69-3 C8H15N5S methylthiotriazine 9 A88

Dialifos 10311-84-9 C14H17ClNO4PS2 organothiophosphate 11 244

Diazinon 333-41-5 C12H21N2O3PS phosphorothioate 11 024

Diazinon oxygen analog 962-58-3 C12H21N2O4P oxon 11 395

Dicamba 1918-00-9 C8H6Cl2O3 benzoic acid 20 155

Dichlobenil 1194-65-6 C7H3Cl2N nitrile 2 324

Dichlofenthion 97-17-6 C10H13Cl2O3PS phenylorganothiophosphate 11 664

Dichlofluanid 1085-98-9 C9H11Cl2FN2O2S2 phenylsulfamide 1 588

Dichlormid 37764-25-3 C8H11Cl2NO herbicide safeners 1 A43

Dichlorobenzophenone o,p' 85-29-0 C13H8Cl2O 707

Dichlorobenzophenone p,p' 90-98-2 C13H8Cl2O 507

Dichlorprop 120-36-5 C9H8Cl2O3 phenoxy acid 20 A25

Dichlorvos (DDVP) 62-73-7 C4H7Cl2O4P phosphoric acid 11 338

Diclofop methyl 51338-27-3 C16H14Cl2O4 aryloxyphenoxypropionic acid 20 299

Dicloran 99-30-9 C6H4Cl2N2O2 nitroaniline 7 144

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PDP Pesticide Codes and Multi-residue Compound Groupings for Fruit and Vegetables

Compound Name CAS# Molecular Formula Chemical Family Group Pesticide 

Code

Diclosulam 145701-21-9 C13H10Cl2FN5O3S triazolopyrimidine herbicides 1 ALU

Dicofol o,p' 10606-46-9 C14H9Cl5O bridged biphenyl 3 253

Dicofol p,p' 115-32-2 C14H9Cl5O bridged biphenyl 3 254

Dicofol Total 115-32-2 C14H9Cl5O bridged biphenyl 3 047

Dicrotophos 141-66-2 C8H16NO5P organophosphate 11 209

Dieldrin 60-57-1 C12H8Cl6O cyclodiene 3 028

Diethofencarb 87130-20-9 C14H21NO4 carbanilite fungicides 22 B62

Difenoconazole 119446-68-3 C19H17Cl2N3O3 triazole 1 B58

Diflubenzuron 35367-38-5 C14H9ClF2N2O2 urea 16 651

Diflufenzopyr 109293-97-2 C15H12F2N4O3 urea 16 AFY

Dimepiperate 61432-55-1 C15H21NOS unclassified 99 E13

Dimethenamid 87674-68-8 C12H18ClNO2S acetamide 1 ADD

Dimethenamid ethanesulfonic acid 205939-58-8 C12H19NO5S2 acetamide metabolite 20 AEX

Dimethenamid oxanilic acid NA[2] C12H17NO4S acetamide metabolite 20 AEY

Dimethenamid P 87674-68-8 C12H18ClNO2S amide 1 AEB

Dimethipin 55290-64-7 C6H10O4S2 urea 16 787

Dimethoate 60-51-5 C5H12NO3PS2 phosphorodithionic acid 11 171

Dimethomorph 110488-70-5 C21H22ClNO4 chlorophenyl morpholine 3 B77

Diniconazole 83657-24-3 C15H17Cl2N3O conazole 1 AFN

Dinocap 131-72-6 C18H24N2O6 dinitrophenol 20 315

Dinoseb 88-85-7 C10H12N2O5 phenol 20 031

Dinotefuran 165252-70-0 C7H14N4O3 neonicotinyl 1 AFO

Dioxacarb 6988-21-2 C11H13NO4 phenylmethyl carbamate 14 656

Dioxathion 78-34-2 C12H26O6P2S4 organothiophosphate 11 103

Diphacinone 82-66-6 C23H16O3 indandione 99 B99

Diphenamid 957-51-7 C16H17NO acetamide 1 330

Diphenylamine (DPA) 122-39-4 C12H11N amine 3 125

Dipropetryn 4147-51-7 C11H21N5S triazine 9 735

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PDP Pesticide Codes and Multi-residue Compound Groupings for Fruit and Vegetables

Compound Name CAS# Molecular Formula Chemical Family Group Pesticide 

Code

Disulfoton 298-04-4 C8H19O2PS3 phosphorodithioate 11 117

Disulfoton oxygen analog NA[2] C8H19O3PS2 organophosphate 11 AHN

Disulfoton oxygen analog sulfone NA[2] C6H15O5PS2 organophosphate 11 AHV

Disulfoton oxygen analog sulfoxide NA[2] C6H15O4PS2 organophosphate 11 AHW

Disulfoton sulfone 2497-06-5 C8H19O4PS sulfone 11 216

Disulfoton sulfoxide 2497-07-6 C8H19O3PS3 sulfoxide 11 706

Ditalimfos 5131-24-8 C12H14NO4PS organophosphorus 11 E22

Dithianon 3347-22-6 C14H4N2O2S2 quinine 17 AHO

Dithiopyr 97886-45-8 C15H16F5NO2S2 pyridine 20 E24

Diuron 330-54-1 C9H10Cl2N2O urea 16 032

Dodine 2439-10-3 C15H33N3O2 aliphatic nitrogenous fungicide 2 104

Emamectin benzoate 155569-91-8 C49H75NO13 + C48H73NO13 avermectin (macrocyclic lactone) 29 AGH

Endosulfan I 959-98-8 C9H6Cl6O3S cyclodiene 3 900

Endosulfan II 33213-65-9 C9H6Cl6O3S cyclodiene 3 901

Endosulfan sulfate 1031-07-8 C9H6Cl6O4S cyclodiene 3 902

Endrin 72-20-8 C12H8Cl6O cyclodiene 3 034

Endothall 145-73-3 C8H10O5 dicarboxylic acid 21 AKV

Epoxiconazole 135319-73-2 C17H13ClFN3O conazole 1 B53

Eprinomectin 123997-26-2

C50H75NO14 (eprinomectin B1a) + 

C49H73NO14 (eprinomectin B1b) macrocyclic lactone 29 AHR

EPN 2104-64-5 C14H14NO4PS phenyl phenylphosphonothioate 

insecticides 11 035

EPTC 759-94-4 C9H19NOS thiocarbamate 14 200

Esfenvalerate 66230-04-4 C25H22ClNO3 pyrethroid 8 714

Ethaboxam 162650-77-3 C14H16N4OS2 amide 1 C90

Ethalfluralin 55283-68-6 C13H14F3N3O4 dinitroaniline 7 721

Ethephon 16672-87-0 C2H6ClO3P plant growth regulator 11 730

Ethiofencarb 29973-13-5 C11H15NO2S carbamate 14 858

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PDP Pesticide Codes and Multi-residue Compound Groupings for Fruit and Vegetables

Compound Name CAS# Molecular Formula Chemical Family Group Pesticide 

Code

Ethiofencarb sulfone 53380-23-7 C11H15NO4S carbamate 14 AMX

Ethiofencarb sulfoxide 53380-22-6 C11H15NO3S carbamate 14 AMY

Ethion 563-12-2 C9H22O4P2S4 phosphorodithioic acid 11 107

Ethion di oxon 22756-17-8 C9H22O6P2S2 oxon 11 538

Ethion mono oxon 17356-42-2 C9H22O5P2S3 oxon 11 AAX

Ethiprole 181587-01-9 C13H9Cl2F3N4OS phenylpyrazole 1 AME

Ethofumesate 26225-79-6 C13H18O5S benzofuranyl alkylsulfonate 11 945

Ethoprop 13194-48-4 C8H19O2PS2 dipropyl phosphorodithioate 11 175

Ethoxyquin 91-53-2 C14H19NO quinoline 99 111

Ethylan 72-56-0 C18H20Cl2 organochlorine 3 066

Etofenprox 80844-07-1 C25H28O3 pyrethroid ether 8 ADI

Etoxazole 1532333-91-1 C21H23F2NO2 oxazole 1 B84

Etridiazole 2593-15-9 C5H5Cl3N2OS thiadiazole 1 722

Etrimfos 38260-54-7 C10H17N2O4PS pyrimidine organothiophosphate 11 293

Famoxadone 131807-57-3 C22H18N2O4 dicarboximide/oxazole 1 AEW

Famphur 52-85-7 C10H16NO5PS2 phenylorganothiophosphate 11 603

Fenamidone 161326-34-7 C17H17N3OS imidazole 1 B64

Fenamiphos 22224-92-6 C13H22NO3PS phosphoramidate 11 236

Fenamiphos sulfone 31972-44-8 C13H22NO5PS sulfone 11 745

Fenamiphos sulfoxide 31972-43-7 C13H22NO4PS sulfoxide 11 746

Fenarimol 60168-88-9 C17H12Cl2N2O pyrimidine 3 271

Fenazaquin 120928-09-8 C20H22N2O unclassified acaricide 27 B73

Fenbuconazole 114369-43-6 C19H17ClN4 conazole 1 A30

Fenbutatin oxide 13356-08-6 C60H28OSn2 organotin acaride 99 639

Fenchlorphos (ronnel) 299-84-3 C8H8Cl3O3PS phenyl organothiophosphate 11 105

Fenhexamid 126833-17-8 C14H17Cl2NO2 chlorocarboximide 1 B41

Fenitrothion 122-14-5 C9H12NO5PS phosphorothioate 11 391

Fenitrothion oxygen analog 2255-17-6 C9H12NO6P oxon 11 648

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PDP Pesticide Codes and Multi-residue Compound Groupings for Fruit and Vegetables

Compound Name CAS# Molecular Formula Chemical Family Group Pesticide 

Code

Fenobucarb (BPMC) 3766-81-2 C12H17NO2 phenyl methylcarbamate 14 856

Fenoxaprop ethyl 66441-23-4 C18H16ClNO5 aryloxyphenoxypropionic acid 20 777

Fenoxycarb 72490-01-8 C17H19NO4 carbamate 14 811

Fenpicoxamid 517875-34-2 C31H38N2O11 amide 1 F92

Fenpropathrin 39515-41-8 C22H23NO3 pyrethroid 8 808

Fenpropidin 67306-00-7 C19H31N nitrogenous hetercyclic 17 AMF

Fenpropimorph 67564-91-4 C20H33NO morpholine 3 886

Fenpyrazamine 473798-59-3 C17H21N3O2S pyrazole 1 AMG

Fenpyroximate 111812-58-9 C24H27N3O4 phenoxypyrazol 1 AFS

Fensulfothion 115-90-2 C11H17O4PS2 phenyl organothiophosphate 11 243

Fenthion 55-38-9 C10H15O3PS2 phosphorothioate 11 177

Fenthion oxygen analog 6552-12-1 C10H15O4PS oxon 11 691

Fenthion sulfone 3761-42-0 C10H15O5PS2 organophosphate 11 660

Fenthion sulfoxide 3761-41-9 C10H15O4PS2 organophosphate 11 AKP

Fenuron 101-42-8 C9H12N2O urea 16 840

Fenvalerate 51630-58-1 C25H22ClNO3 pyrethroid 8 546

Fipronil 120068-37-3 C12H4Cl2F6N4OS phenyl pyrazole 1 A82

Fipronil sulfone 120068-36-2 C12H4Cl2F6N4O2S phenylpyrazole 1 A84

Flazasulfuron 104040-78-0 C13H12F3N5O5S pyridiminyl sulfonylurea 16 G38

Flonicamid 158062-67-0 C9H6F3N3O nicotinoid 1 AGG

Fluazifop 69335-91-7 C15H12F3NO4 pyridine 17 ALW

Fluazifop butyl 69806-50-4 C15H12F3NO4 pyridine 17 292

Fluazifop-P-butyl 79241-46-6 C19H20F3NO4 pyridine 17 E40

Fluazinam 79622-59-6 C13H4Cl2F6N4O4 pyridine 17 B54

Flubendiamide 272451-65-7 C23H22F7IN2O4S diamide 17 or 1 AHS

Flucythrinate 70124-77-5 C26H23F2NO4 pyrethroid 8 229

Fludioxonil 131341-86-1 C12H6F2N2O2 phenyl pyrrole 1 B23

Fluensulfone 318290-98-1 C7H5ClF3NO2S2 unclassified nematicide 99 ANK

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PDP Pesticide Codes and Multi-residue Compound Groupings for Fruit and Vegetables

Compound Name CAS# Molecular Formula Chemical Family Group Pesticide 

Code

Flufenacet 142459-58-3 C14H13F4N3O2S anilide 1 B30

Flufenacet ethanesulfonic acid NA[2] C11H14FNO4S anilide metabolite 20 AFH

Flufenacet oxanilic acid 201668-31-7 C11H12FNO3 anilide metabolite 20 AEZ

Flufenoxuron 101463-69-8 C21H11ClF6N2O3 urea 16 AHG

Flufenpyr ethyl 188489-07-8 C16H13ClF4N2O4 pyridazinone 17 ALR

Flumetralin 62924-70-3 C16H12ClF4N3O4 growth inhibitor 7 834

Flumetsulam 98967-40-9 C12H9F2N5O2S pyrimidine 1 AAU

Flumiclorac pentyl 87546-18-7 C21H23ClFNO5 dicarboximide 1 AAV

Flumioxazin 103361-09-7 C19H15FN2O2 N-phenylphthalimide 1 AFF

Fluometuron 2164-17-2 C10H11F3N2O urea 16 701

Fluopicolide 239110-15-7 C14H8Cl3F3N2O pyridine 17 or 1 AHT

Fluopyram 658066-35-4 C16H11ClF6N2O benzamide 1 AKG

Fluorodifen 15457-05-3 C13H7F3N2O5 nitrophenyl ether 3 836

Fluoxastrobin 361377-29-9 C21H16ClFN4O5 strobilurin 22 AGJ

Flupyradifurone 951659-40-8 C12H11ClF2N2O2 unclassified 1 ANE

Fluquinconazole 136426-54-5 C16H8Cl2FN5O aryloxyphenoxypropionic acid 1 B78

Fluridone 59756-60-4 C19H14F3NO pyridine 17 736

Fluroxapyr-1-methylheptyl ester 81406-37-3 C15H22Cl2FN2O3 pyridine 17 ADJ

Flusilazole 85509-19-9 C16H15F2N3Si conazole 1 950

Fluthiacet methyl 117337-19-6 C15H15ClFN3O3S2 phenylpyrazole 1 AGM

Flutianil 958647-10-4 C19H14F4N2OS2 thiazolidine fungicide 1 F96

Flutolanil 66332-96-5 C17H16F3NO2 caboxamide 1 B63

Flutriafol 76674-21-0 C16H13F2N3O conazole 1 AFM

Fluvalinate 69409-94-5 C26H22ClF3N2O3 pyrethroid 8 297

Fluxapyroxad 907204-31-3 C18H12F5N3O anilide; pyrazole 22 AKW

Folpet 133-07-3 C9H4Cl3NO2S phthalimide 1 126

Fomesafen 72178-02-0 C15H10ClF3N2O6S amide or nitrophenyl ether herbicide 1 or 3 ALX

Fonofos 944-22-9 C10H15OPS2 phosphorodithioic acid 11 163

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PDP Pesticide Codes and Multi-residue Compound Groupings for Fruit and Vegetables

Compound Name CAS# Molecular Formula Chemical Family Group Pesticide 

Code

Fonofos oxygen analog 944-21-8 C10H15O2PS oxon 11 692

Forchlorfenuron 68157-60-8 C12H10ClN3O phenyl urea 16 B32

Formetanate hydrochloride 23422-53-9 C11H15N3O2 formamidine 1 723

Fosthiazate 98886-44-3 C9H18NO3PS2 organothiophosphate 11 B09

Furalaxyl 57646-30-7 C17H19NO4 furanilide 1 AMZ

Furathiocarb 65907-30-4 C18H26N2O5S benzofurayl methyl carbamate 14 AMR

Glufosinate 77182-82-2 C5H12NO4P quaternary ammonium 99 AJL

Glyphosate 1071-83-6 C3H8NO5P organophosphate 99 653

Halosulfuron 135397-30-7 C12H13ClN6O7S sulfonyl urea 16 AFK

Halosulfuron methyl 100784-20-1 C12H13ClN6O7S sulfonyl urea 16 AEH

Haloxyfop 69806-34-4 C15H11ClF3NO4 aryloxyphenoxypropionic acid 20 798

Heptachlor 76-44-8 C10H5Cl7 cyclodiene 3 044

Heptachlor epoxide 1024-57-3 C10H5Cl7O cyclodiene 3 143

Heptenophos 23560-59-0 C9H12ClO4P organophosphate 11 841

Hexachlorobenzene (HCB) 118-74-1 C6Cl6 benzene ring 3 321

Hexaconazole 79983-71-4 C14H17Cl2N3O conazole 1 954

Hexaflumuron 86479-06-3 C16H8Cl2F6N2O3 benzoylphenylurea chitin synthesis inhib 16 AMA

Hexazinone 51235-04-2 C12H20N4O2 triazine 9 633

Hexythiazox 78587-05-0 C17H21ClN2O2S thiazolidine carboxamide 1 B10

Hydroprene 41096-46-2 C17H30O2 oxyhydrocarbon 21 AEC

Hydroxy Acequinocyl 57960-31-3 C22H30O3 unclassified acaricide 99 AOH

Hydroxy atrazine 2163-68-0 C8H15N5O triazine metabolite 9 AED

Imazalil 35554-44-0 C14H14Cl2N2O conazole 1 604

Imazamethabenz acid NA[2] C15H18N2O3 imidazolinone 16 AEE

Imazamethabenz methyl 81405-85-8 C16H20N2O3 imidazolinone 16 753

Imazamox 114311-32-9 C15H19N3O4 imidazolinone 16 ACA

Imazapic 104098-48-8 C14H17N3O3 imidazolinone 16 ACZ

Imazapyr 81334-34-1 C13H15N3O3 imidazolinone 16 ACB

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PDP Pesticide Codes and Multi-residue Compound Groupings for Fruit and Vegetables

Compound Name CAS# Molecular Formula Chemical Family Group Pesticide 

Code

Imazaquin 81335-37-7 C17H17N3O3 imidazolinone 16 ACC

Imazethapyr 81335-77-5 C15H19N3O3 imidazolinone 16 ACD

Imazosulfuron 122548-33-8 C14H13ClN6O5S sulfonyl urea 16 AMK

Imidacloprid 138261-41-3 C9H10ClN5O2 neonicotinyl 1 967

Imidacloprid desnitro 127202-53-3 C9H11ClN4 neonicotinyl metabolite 1 AOG

Imidacloprid urea 120868-66-8 C9H10ClN3O neonicotinyl metabolite 1 AHF

Imiprothrin 72963-72-5 C17H22N2O4 pyrethroid 8 ADK

Indaziflam 950782-86-2 C16H20FN5 triazine 9 AJP

Indoxacarb 173584-44-6 C22H17ClF3N3O7 carbamate 14 ADG

Iodosulfuron methyl 144550-36-7 C14H14IN5O6S triazinylsulfonyl urea 16 AKB

Ipconazole 125225-28-7 C18H24ClN3O conazole 1 AHY

Iprobenfos 26087-47-8 C13H21O3PS organophosphate 11 867

Iprodione 36734-19-7 C13H13Cl2N3O3 dicarboximide 1 626

Iprodione metabolite isomer 63637-89-8 C13H13Cl2N3O3 dicarboximide 1 231

Iprovalicarb 140923-17-7 C18H28N2O3 carbamates 14 AGE

Isocarbophos 24353-61-5 C11H16NO4PS phosphoramidothioate 11 ALE

Isofenphos 25311-71-1 C15H24NO4PS organophosphate 11 258

Isofenphos methyl 99675-03-3 C14H22NO4PS phosphoramidothioate 11 ANA

Isofenphos oxygen analog 31120-85-1 C15H24NO5P oxon 11 655

Isofetamid 875915-78-9 C20H25NO3S amide/thiophene 1 ANH

Isoprocarb 2631-40-5 C11H15NO2 carbamate 14 637

Isoprothiolane 50512-35-1 C12H18O4S2 unclassified 99 855

Isoproturon 34123-59-6 C12H18N2O phenyl urea 16 843

Isopyrazam 881685-58-1 C20H23F2N3O pyrazole 1 AKX

Isoxaben 82558-50-7 C18H24N2O4 amide herbicide 1 B14

Isoxadifen ethyl 163520-33-0 C18H17NO3 herbicide safeners 1 AGL

Isoxaflutole 141112-29-0 C15H12F3NO4S cyclopropylisoxazole 17 B15

Kasugamycin 6980-18-3 C14H25N3O9 bactericide 99 AKY

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PDP Pesticide Codes and Multi-residue Compound Groupings for Fruit and Vegetables

Compound Name CAS# Molecular Formula Chemical Family Group Pesticide 

Code

Kinoprene 42588-37-4 C18H28O2 oxyhydrocarbon 21 E66

Kresoxim methyl 143390-89-0 C18H19NO4 strobilurin 22 B42

Lactofen 77501-63-4 C19H15ClF3NO7 flurodiphenyl ether 3 A38

Leptophos oxygen analog 25006-32-0 C13H10BrCl2O3P oxon 11 A40

Lenacil 2164-08-1 C13H18N2O2 uracil 16 859

Lindane (BHC gamma) 58-89-9 C6H6Cl6 hexane ring 3 050

Linuron 330-55-2 C9H10Cl2N2O2 urea 16 129

Lufenuron 103055-07-8 C17H8Cl2F8N2O3 benzoylphenylurea 16 AJV

Malathion 121-75-5 C10H19O6PS2 phosphorodithioate 11 052

Malathion oxygen analog 1634-78-2 C10H19O7PS oxon 11 208

Mancozeb 8018-01-07 C8H12MnN4S8Zn dithiocarbamate 99 128

Mandestrobin 173662-97-0 C19H23NO3 strobilurin 22 F41

Mandipropamid 374726-62-2 C23H22ClNO4 amide 1 AGX

MCPA 94-74-6 C9H9ClO3 phenoxy 20 318

MCPB 94-81-5 C11H13ClO3 phenoxy acid 20 620

Mecarbam 2595-54-2 C10H20NO5PS2 organophosphate 11 662

Mecoprop (MCPP) 7085-19-0 C10H11ClO3 phenoxy acid 20 A42

Mefenacet 73250-68-7 C16H14N2O2S anilide 1 D21

Mefenpyr diethyl 135590-91-9 C16H18Cl2N2O4 herbicide safeners 1 AKH

Mefentrifluconazole 1417782-03-6 C18H15ClF3N3O2 triazole 1 G21

Melamine 108-78-1 C3H6N6 trimer of cyanamide 9 260

Mepanipyrim 1102335-47-7 C14H13N3 pyrimidine 17 AGF

Mephosfolan 950-10-7 C8H16NO3PS2 phosphoramidate 11 242

Merphos 150-50-5 C12H27PS3 plant growth regulator 11 121

Mesosulfuron methyl 208465-21-8 C17H21N5O9S2 pyrimidinylsulfonyl urea 16 AKJ

Mesotrione 104206-82-8 C14H13NO7S benzoylcyclohexanedione 1 AJA

Metaflumizone 139968-49-3 C24H16F6N4O2 unclassified 1 AJW

Metalaxyl 57837-19-1 C15H21NO4 acylalanine 1 607

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PDP Pesticide Codes and Multi-residue Compound Groupings for Fruit and Vegetables

Compound Name CAS# Molecular Formula Chemical Family Group Pesticide 

Code

Metaldehyde 108-62-3 C8H16O4 polyaldehyde 99 B07

Metconazole 125116-23-6 C17H22ClN3O conazole 1 AHX

Metolcarb 1129-41-5 C9H11NO2 carbamate 14 860

Metrafenone 220899-03-6 C19H21BrO5 arylphenylketone 3 ANF

Methamidophos 10265-92-6 C2H8NO2PS phosphoramidothioic acid 11 170

Methacrifos 62610-77-9 C7H13O5PS organothiophosphate 11 E74

Methidathion 950-37-8 C6H11N2O4PS3 phosphorodithioate 11 197

Methidathion oxygen analog 39856-16-1 C6H11N2O5PS2 oxon 11 ACE

Methiocarb 2032-65-7 C11H15NO2S carbamate 14 195

Methiocarb sulfone 2179-25-1 C11H15NO4S carbamate metabolilte 14 634

Methiocarb sulfoxide 2635-10-1 C11H15NO3S carbamate metabolilte 14 256

Methomyl 16752-77-5 C5H10N2O2S carbamate 14 159

Methoprene 40596-69-8 C19H34O3 oxyhydrocarbon 21 ACV

Methoxychlor olefin 2132-70-9 C16H14Cl2O2 bridged biphenyl 3 276

Methoxychlor p,p' 72-43-5 C16H15Cl3O2 bridged biphenyl 3 275

Methoxychlor Total 72-43-5 C16H15Cl3O2 bridged biphenyl 3 055

Methoxyfenozide 161050-58-4 C22H28N2O3 diacylhydrazine 16 AES

Methyl pentachlorophenyl sulfide (MPCPS) 1825-19-0 C7H3Cl5S benzene ring 3 388

Metolachlor 51218-45-2 C15H22ClNO2 acetamide 1 283

Metolachlor ethanesulfonic acid NA[2] C15H23NO5S chloroacetanilide metabolite 20 ACG

Metolachlor oxanilic acid 152019-73-3 C15H21NO4 chloroacetanilide metabolite 20 ACH

Metribuzin 21087-64-9 C8H14N4OS triazines 9 181

Metsulfuron methyl 74223-64-6 C14H15N5O6S sulfonyl urea 16 ACI

Mevinphos E/Z 298-01-1 C7H13O6P butenoic acid 11 579

MGK-264 113-48-4 C17H25NO2 synergist 8 058

MGK-326 (Dipropyl isocinchomeronate) 136-45-8 C13H17NO4 synergist 8 ADL

Milbemectin 51596-10-2

C31H44O7 (milbemycin A3) + 

C32H46O7 (milbemycin A4) macrocyclic lactone 29 AHP

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PDP Pesticide Codes and Multi-residue Compound Groupings for Fruit and Vegetables

Compound Name CAS# Molecular Formula Chemical Family Group Pesticide 

Code

Mirex 2385-85-5 C10Cl12 cyclodiene 3 352

Molinate 2212-67-1 C9H17NO5 thiocarbamate 14 778

Monocrotophos 6923-22-4 C7H14NO5P phosphoric acid 11 343

Monolinuron 1746-81-2 C9H11ClN2O2 phenyl urea 16 682

Monuron 150-68-5 C9H11ClN2O urea 16 046

Myclobutanil 88671-89-0 C15H17ClN4 triazole 1 679

Naled 300-76-5 C4H7Br2Cl2O4P organophosphate 11 303

Napropamide 15299-99-7 C17H21NO2 amide 1 594

Naptalam (Alanap) 132-66-1 C18H13NO3 amide 1 B18

Neburon 555-37-3 C12H16Cl2N2O urea 16 061

Niclosamide 50-65-7 C13H8Cl2N2O4 molluscicide 3 ACL

Nicosulfuron 111991-09-4 C15H18N6O6S sulfonyl urea 16 ACM

Nitrapyrin 1929-82-4 C6H3Cl4N pyridine 17 725

Nitrofen 1836-75-5 C12H7Cl2NO3 nitrophenyl ether herbicides 3 158

Norflurazon 27314-13-2 C12H9ClF3N3O pyridazinone 17 596

Norflurazon desmethyl 23576-24-1 C11H7ClF3N3O pyridazinone 17 720

Novaluron 116714-46-6 C17H9ClF8N2O4 benzoyl urea 16 AFX

Omethoate 1113-02-6 C5H12NO4PS phosphorothioate 11 178

o-Phenylphenol 90-43-7 C12H10O biphenyl 3 083

Oryzalin 19044-88-3 C12H18N4O6S dinitroaniline 7 737

Oxadiazon 19666-30-9 C15H18Cl2N2O3 oxadiazon 1 625

Oxadixyl 77732-09-3 C14H18N2O4 oxazolidine 1 A46

Oxamyl 23135-22-0 C7H13N3O3S carbamate 14 537

Oxamyl oxime 30558-43-1 C5H10N2O2S carbamate 14 A47

Oxathiapiprolin 1003318-67-9 C24H22F5N5O2S pyrazole 1 F56

Oxychlordane 27304-13-8 C10H4Cl8O cyclodiene 3 349

Oxydemeton methyl 301-12-2 C6H15O4PS2 organophosphate 11 219

Oxydemeton methyl sulfone 17040-19-6 C6H15O5PS2 phosphorothioate 11 245

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Compound Name CAS# Molecular Formula Chemical Family Group Pesticide 

Code

Oxyfluorfen 42874-03-3 C15H11ClF3NO4 diphenyl ether 3 713

Oxythioquinox 2439-01-2 C10H6N2OS2 quionoxaline 17 246

Paclobutrazol 76738-62-0 C15H20ClN3O growth inhibitor 1 A48

Parathion ethyl 56-38-2 C10H14NO5PS phosphorothionic acid 11 065

Parathion ethyl oxygen analog NA[2] C10H14NO6P oxon 11 370

Parathion methyl 298-00-0 C8H10NO5PS phosphorothionic acid 11 057

Parathion methyl oxygen analog 950-35-6 C8H10NO6P oxon 11 779

Pebulate 1114-71-2 C10H21NOS thiocarbamate 14 161

Penconazole 66246-88-6 C13H15Cl2N3 conazole 1 956

Pencycuron 66063-05-6 C19H21ClN2O urea 16 AJX

Pendimethalin 40487-42-1 C13H19N3O4 dinitroaniline 7 230

Penflufen 494793-67-8 C18H24FN3O pyrazole 1 AKZ

Penoxsulam 219714-96-2 C16H14F5N5O5S triazolpyrimidine 1 AMS

Pentachloroaniline (PCA) 527-20-8 C6H2Cl5N aniline 3 351

Pentachlorobenzene (PCB) 608-93-5 C6HCl5 benzene ring 3 387

Penthiopyrad 183675-82-3 C16H20F3N3OS pyridazinone 22 AKD

Permethrin cis 61949-76-6 C21H20Cl2O3 pyrethroid 8 222

Permethrin total 52645-53-1 C21H20Cl2O3 pyrethroid 8 539

Permethrin trans 61949-77-7 C21H20Cl2O3 pyrethroid 8 223

Perthane 72-56-0 C18H20Cl2 organochlorine 3 AGN

Phenmedipham 13684-63-4 C16H16N2O4 carbamate 14 791

Phenothrin 26002-80-2 C23H26O3 pyrethroid 8 848

Phenthoate 2597-03-7 C12H17O4PS2 organophosphate 11 377

Phorate 298-02-2 C7H17O2PS3 phosphorodithionic acid 11 148

Phorate oxygen analog 2600-69-3 C7H17O3PS2 oxon 11 928

Phorate oxygen analog sulfone 2588-06-9 C7H17O5PS2 organophosphate 11 966

Phorate oxygen analog sulfoxide 2588-05-8 C7H17O4PS2 organophosphate 11 951

Phorate sulfone 2588-04-7 C7H17O4PS3 sulfone 11 189

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PDP Pesticide Codes and Multi-residue Compound Groupings for Fruit and Vegetables

Compound Name CAS# Molecular Formula Chemical Family Group Pesticide 

Code

Phorate sulfoxide 2588-03-6 C7H17O3PS2 sulfoxide 11 190

Phosalone 2310-17-0 C12H15ClNO4PS2 phosphorodithionic acid 11 166

Phosalone oxygen analog 2275-06-1 C12H15ClNO5PS oxon 11 929

Phosmet 732-11-6 C11H12NO4PS2 phosphorodithionic acid 11 165

Phosmet oxygen analog 3735-33-9 C11H12NO5PS oxon 11 237

Phosphamidon 13171-21-6 C10H19ClNO5P dimethyl phosphate 11 203

Phoxim 14816-18-3 C12H15N2O3PS organothiophosphate 11 247

Picloram 1918-02-1 C6H3Cl3N2O2 carboxylic acid 20 329

Picoxystrobin 117428-22-5 C18H16F3NO4 strobilurin 22 ALA

Pinoxaden 243973-20-8 C23H32N2O4 phenylpyrazole 22 AHH

Piperalin 3478-94-2 C16H21Cl2NO2 unclassified 99 AGV

Piperonyl butoxide 51-03-6 C19H30O5 benzodioxole 8 070

Pirimicarb 23103-98-2 C11H18N4O2 carbamate 14 580

Pirimicarb desmethyl 30614-22-3 C10H16N4O2 dimethylcarbamate metabolite 14 873

Pirimiphos methyl 29232-93-7 C11H20N3O3PS phosphorothioate 11 562

Prallethrin 23031-36-9 C19H24O3 pyrethroid 8 ADC

Pretilachlor 51218-49-6 C17H26ClNO2 chloroacetanilide 1 892

Primisulfuron 113036-87-6 C14H10F4N4O7S pyrimidinylsulfonyl urea 16 AHA

Prochloraz 67747-09-5 C15H16Cl3N3O2 imidazole 9 833

Procymidone 32809-16-8 C13H11Cl2NO2 dicarboximide 1 593

Prodiamine 29091-21-2 C13H17F3N4O4 dinitroaniline 7 814

Profenofos 41198-08-7 C11H15BrClO3PS phosphorothioate 11 224

Profluralin 26399-36-0 C14H16F3N3O4 dinitroaniline 7 A53

Profoxydim 139001-49-3 C24H32ClNO4S cyclohexene oxime 28 ANB

Prohexadione calcium 127277-53-6 C20H22CaO10 unclassified plant growth regulator 99 ALO

Promecarb 2631-37-0 C12H17NO2 phenyl methylcarbamate 14 385

Prometon 1610-18-0 C10H19N5O triazine 9 942

Prometryn 7287-19-6 C10H19N5S triazine 9 249

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PDP Pesticide Codes and Multi-residue Compound Groupings for Fruit and Vegetables

Compound Name CAS# Molecular Formula Chemical Family Group Pesticide 

Code

Pronamide (propyzamide) 23950-58-5 C12H11Cl2NO amide 1 540

Propachlor 1918-16-7 C11H14ClNO chloroacetanilide 1 675

Propachlor oxanilic acid 70628-36-3 C11H13NO3 chloroacetanilide metabolite 20 AFA

Propamocarb hydrochloride 25606-41-1 C9H20N2O2 carbamate 14 AFU

Propanil 709-98-8 C9H9Cl2NO anilide 1 341

Propaquizafop 111479-05-1 C22H22ClN3O5 aryloxyphenoxypropionic acid 17 ALK

Propargite 2312-35-8 C19H26O4S sulfite 1 623

Propazine 139-40-2 C9H16ClN5 triazine 9 333

Propetamphos 31218-83-4 C10H20NO4PS phosphorothioate 11 636

Propham 122-42-9 C10H13NO2 carbamate 14 310

Propiconazole 60207-90-1 C15H17Cl2N3O2 conazole 1 264

Propoxur 114-26-1 C11H15NO3 carbamate 14 162

Propoxycarbazone 145026-81-9 C15H18N4O7S triazolone 1 AKK

Proquinazid 189278-12-4 C14H17IN2O2 unclassified 17 AMM

Prosulfuron 94125-34-5 C15H16F3N5O4S triazinylsulfonyl urea 16 AEG

Prothioconazole 178928-70-6 C14H15Cl2N3OS conazole 1 AHJ

Prothioconazole desthio 120983-64-4 C14H15Cl2N3O conazole 1 F00

Prothiofos 34643-46-4 C11H15Cl2O2PS2 phenylorganothiophosphate 11 613

Pydiflumetofen 1228284-64-7 C16H16Cl3F2N3O2 pyrazole 1 G03

Pymetrozine 123312-89-0 C10H11N5O azomethine 9 ABF

Pyraclofos 77458-01-6 C14H18ClN2O3PS heterocyclic organothiophosphate 11 F01

Pyraclostrobin 175013-18-0 C19H18ClN3O4 strobilurin 22 B61

Pyraflufen 129630-17-7 C13H9Cl2F3N2O4 phenylpyrazole 1 ALY

Pyraflufen ethyl 129630-19-9 C15H13Cl2F3N2O4 phenoxypyrazole 1 AGB

Pyrasulfotole 365400-11-9 C14H13F3N2O4S benzoylpyrazole 1 AHK

Pyrazon (Chloridazon) 1698-60-8 C10H8ClN3O pyridazinone 17 595

Pyrazophos 13457-18-6 C14H20N3O5PS organophosphate 11 553

Pyrethrins 8003-34-7 C21H27O4 pyrethrum, botanical 8 075

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PDP Pesticide Codes and Multi-residue Compound Groupings for Fruit and Vegetables

Compound Name CAS# Molecular Formula Chemical Family Group Pesticide 

Code

Pyridaben 96489-71-3 C19H25ClN2OS pyridazinone 17 B56

Pyridalyl 179101-81-6 C18H14Cl4F3NO3 pyridine 17 AHU

Pyridaphenthion 119-12-0 C14H17N2O4PS organophosphate 11 961

Pyrifluquinazon 337458-27-2 C19H15F7N4O2 Nitrogenous heterocyclics 17 F08

Pyrimethanil 53112-28-0 C12H13N3 pyrimidine 17 B16

Pyriofenone 688046-61-9 C18H20ClNO5 arylphenylketone 3 F12

Pyriproxyfen 95737-68-1 C20H19NO3 pyridine 17 B24

Pyroxasulfone 447399-55-5 C12H14F5N3O4S pyrazole 1 AMO

Quinalphos 13593-03-8 C12H15N2O3PS organothiophosphate 11 661

Quinchlorac 84087-01-4 C10H5Cl2NO2 quinolinecarboxylic acid 20 B29

Quinoxyfen 124495-18-7 C15H8Cl2FNO pyridine 17 B57

Quintozene (PCNB) 82-68-8 C6Cl5NO2 benzene ring 3 304

Quizalofop 76578-12-6 C17H13ClN2O4 aryloxyphenoxypropionic hebicide 20 ALZ

Quizalofop ethyl 76578-14-8 C19H17ClN2O4 aryloxyphenoxypropionic acid 20 750

Resmethrin 10453-86-8 C22H26O3 pyrethroid 8 556

RH 9129 146887-38-9 C19H16N3ClO2 fenbuconazole metabolite 1 A54

RH 9130 146887-37-8 C19H16N3ClO2 fenbuconazole metabolite 1 A55

Rimsulfuron 122931-48-0 C14H17N5O7S2 sulfonyl urea 16 AJF

Rotenone 83-79-4 C23H22O6 botanical insecticide 8 020

S-(2-hydroxy)propyl EPTC 759-94-4 C9H19NOS thiocarbamate 14 ACO

S-Bioallethrin 28434-00-6 C19H26O3 pyrethroid 8 A57

Saflufenacil 372137-35-4 C17H17ClF4N4O5S urea 16 AHZ

Sedaxane 874967-67-6 C18H19F2N3O pyrazole 1 ALB

Sethoxydim 74051-80-2 C17H29NO3S cyclohexene oxime 28 AEV

Sethoxydim sulfoxide 114480-24-9 C17H29NO4S cyclohexene oxime 28 AJR

Siduron 1982-49-6 C14H20N2O urea 16 ACT

Simazine 122-34-9 C7H12ClN5 triazine 9 149

Simetryn 1014-70-6 C8H15N5S triazine 9 837

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PDP Pesticide Codes and Multi-residue Compound Groupings for Fruit and Vegetables

Compound Name CAS# Molecular Formula Chemical Family Group Pesticide 

Code

Spinetoram 187166-40-1 C42H69NO10 + C43H69NO10 spinosyn (macrocyclic lactone) 29 AGY

Spinosad 168316-95-8 C41H65NO10 + C42H67NO10 spinosyn (macrocyclic lactone) 29 ABB

Spirodiclofen 148477-71-8 C21H24Cl2O4 tetronic acid 27 B85

Spiromesifen 283594-90-1 C23H30O4 tetronic acid 27 AGT

Spiromesifen enol metabolite 148476-30-6 C17H20O3 tetronic acid metabolite 27 AGU

Spiromesifen, total (including enol metabolite) 283594-90-1 C23H30O4 + C17H20O3 tetronic acid 27 AFW

Spirotetramat 203313-25-1 C21H27NO5 tetramic acid insecticide 27 AHM

Spiroxamine 118134-30-8 C18H35NO2 unclassified 99 AJY

Sulfallate 95-06-7 C8H14ClNS2 thiocarbamate 14 323

Sulfentrazone 122836-35-5 C11H10Cl2F2N4O3S triazole sulfonamide 1 AAY

Sulfometuron methyl 74222-97-2 C15H16N4O5S sulfonyl urea 16 ACP

Sulfosulfuron 141776-32-1 C16H18N6O7S2 pyrimidinylsulfonyl urea 16 ADS

Sulfotep 3689-24-5 C8H20O5P2S2 organophosphate 11 311

Sulfoxaflor 946578-00-3 C10H10F3N3OS sulfoximine 99 ALS

Sulprofos 35400-43-2 C12H19O2PS3 organophosphate 11 609

Sulprofos oxygen analog 38527-90-1 C12H19O3PS2 oxon 11 ACQ

TCMTB 21564-17-0 C9H6N2S3 benzothiazole 17 793

Tebuconazole 107534-96-3 C16H23ClN3O conazole 1 A58

Tebufenozide 112410-23-8 C22H28N2O2 diacylhydrazine 16 ABG

Tebufenpyrad 119168-77-3 C18H24ClN3O pyrazole 1 AJZ

Tebupirimfos 96182-53-5 C13H23N2O3PS organophosphate 11 A59

Tebupirimfos oxygen analog NA[2] C13H23N2O4P oxon 11 ACR

Tebuthiuron 34014-18-1 C9H16N4OS urea 16 780

Tecnazene 117-18-0 C6HCl4NO2 nitrobenzene 3 147

Teflubenzuron 83121-18-0 C14H6Cl2F4N2O2 benzoylphenylurea 16 AKA

Tefluthrin 79538-32-2 C17H14ClF7O2 pyrethroid 8 B26

TEPP 107-49-3 C8H20O7P2 organophosphate 11 088

Tepraloxydim 149979-41-9 C17H24ClNO4 cyclohexene oxime 28 AHL

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PDP Pesticide Codes and Multi-residue Compound Groupings for Fruit and Vegetables

Compound Name CAS# Molecular Formula Chemical Family Group Pesticide 

Code

Terbacil 5902-51-2 C9H13ClN2O2 uracil 16 152

Terbufos 13071-79-9 C9H21O2PS3 phosphorothioate 11 205

Terbufos oxygen analog 56070-14-5 C9H21O3PS2 oxon 11 A60

Terbufos oxygen analog sulfone 56070-15-6 C9H21O5PS2 organophosphate 11 752

Terbufos sulfone 56070-16-7 C9H21O4PS3 sulfone 11 963

Terbufos Sulfoxide 10548-10-4 C9H21O4PS2 organophosphate 11 AMP

Terbutryn 886-50-0 C10H19N5S methylthiotriazine 9 738

Terbuthylazine 5915-41-3 C9H16ClN5 chlorotriazine 9 678

Tetrachlorvinphos 22248-79-9 C10H9Cl4O4P chlorethylene phosphate 11 176

Tetraconazole 112281-77-3 C13H11Cl2F4N3O conazole 1 B72

Tetradifon 116-29-0 C12H6Cl4O2S bridged biphenyl 3 108

Tetrahydrophthalimide (THPI)[1] 1469-48-3 C8H9NO2 phthalimide 1 624

Tetramethrin 7696-12-0 C19H25NO4 pyrethroid 8 947

Tetraniliprole 1229654-66-3 C22H16ClF3N10O2 diamide; pyrazole G27

Thiabendazole 148-79-8 C10H7N3S benzimidazole 1 157

Thiacloprid 111988-49-9 C10H9ClN4S neonicotinyl 1 B68

Thiamethoxam 153719-23-4 C8H10ClN5O3S neonicotinyl 1 B43

Thiazopyr 117718-60-2 C16H17F5N2O2S pyridine 17 B12

Thidiazuron 51707-55-2 C9H8N4OS plant growth regulator 16 794

Thiencarbazone methyl 317815-83-1 C12H14N4O7S2 triazolone 4 AKL

Thifensulfuron 79277-67-1 C11H11N5O6S2 sulfonyl urea 16 AEF

Thifensulfuron methyl 79227-27-3 C12H13N5O6S2 triazinylsulfonyl urea 16 AEQ

Thiobencarb 28249-77-6 C12H16ClNOS thiocarbamate 14 726

Thiodicarb 59669-26-0 C10H18N4O4S3 carbamate 14 943

Thionazin 297-97-2 C8H13N2O3PS organophosphate 11 250

Thiophanate methyl 23564-05-8 C12H14N4O4S2 carbamate 14 611

Thiram 137-26-8 C6H12N2S4 dithiocarbamate 99 089

Thymol 89-83-8 C10H14O phenol 3 ALG

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PDP Pesticide Codes and Multi-residue Compound Groupings for Fruit and Vegetables

Compound Name CAS# Molecular Formula Chemical Family Group Pesticide 

Code

Tolclofos methyl 57018-04-9 C9H11Cl2O3PS organophosphate 11 B70

Tolfenpyrad 129558-76-5 C21H22ClN3O2 pyrazole 1 ANC

Tolyfluanid 731-27-1 C10H13Cl2FN2O2S2 phenylsulfamide 1 649

Topramezone 210631-68-8 C16H17N3O5S benzoylpyrazole 1 AMO

Toxaphene 8001-35-2 C10H10Cl8 organochlorine 3 090

Tralomethrin 66841-25-6 C22H19Br4NO3 pyrethroid 8 755

Triadimefon 43121-43-3 C14H16ClN3O2 conazole 1 608

Triadimenol 55219-65-3 C14H18ClN3O2 conazole 1 638

Triallate 2303-17-5 C10H16Cl3NOS thiocarbamate 14 621

Triasulfuron 82097-50-5 C14H16ClN5O5S sulfonyl urea 16 ADP

Triazole acetic acid 28711-29-7 C4H6N3O2 triazole metabolite 1 ADX

Triazole alanine 86362-20-1 C5H8N4O2 triazole metabolite 1 ADW

Triazophos 24017-47-8 C12H16N3O3PS organothiophosphate 11 536

Tribenuron methyl 101200-48-0 C15H17N5O6S triazinylsulfonyl urea 16 ACS

Trichlorfon (as dichlorvos) 52-68-6 C4H8Cl3O4P phosphate 11 130

Trichloronate 327-98-0 C10H12Cl3O2PS organothiophosphate 11 569

Triclopyr 55335-06-3 C7H4Cl3NO3 acetic acid 20 731

Tricyclazole 41814-78-2 C9H7N3S benzothiazole 4 804

Tridemorph 24602-86-6 C19H39NO morpholine 3 795

Trifloxystrobin 221007-60-9 C20H19F3N2O4 strobilurin 22 B79

Trifloxysulfuron 145099-21-4 C14H14F3N5O6S sulfonyl urea 16 AJG

Triflumizole 68694-11-1 C15H15ClF3N3O conazole 1 A61

Trifluralin 1582-09-8 C13H16F3N3O4 dinitroaniline 7 151

Triforine 26644-46-2 C10H14Cl6N4O2 formamide 1 915

Triticonazole 131983-72-7 C17H20ClN3O conazole 1 ADR

Uniconazole 83657-22-1 C15H18ClN3O conazole 1 AJJ

Valifenalate 283159-90-0 C19H27ClN2O5 acylamino acid fungicides 14 F49

Vernolate 1929-77-7 C10H21NOS thiocarbamate 14 201

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PDP Pesticide Codes and Multi-residue Compound Groupings for Fruit and Vegetables

Compound Name CAS# Molecular Formula Chemical Family Group Pesticide 

Code

Vinclozolin 50471-44-8 C12H9Cl2NO3 dichloroanilide 1 529

Zoxamide 156052-68-5 C14H16Cl3NO2 benzamide 1 B44

[1] Metabolite of captan and captafol.

[2] Not available.

USDA/AMS Sceince and Technology 26

PDP QC Attachment 2

Revision 12 - Effective June 1, 2023
EPA, Codex, and Food and Drug Administration (FDA) Pesticide Analytical Manual (PAM) Commodity Groupings

PDP 

Code

PDP Commodity 

Group EPA Codex

AL Cereal Grains (High Oil) Tree nuts Tree nuts

Fruit AP Pome fruits Med. Sugar

Juice AJ Fruit juice Med. Sugar

Sauce AC Manufactured food single ingredient High Sugar

Baby Food IA Manufactured food single ingredient

Single serving AX Pome fruits Med. Sugar

AS Fruits and Vegetables Miscellaneous Stalk & stem vegs. Non-fatty Low Sugar

AV Fruits and Vegetables Miscellaneous Assorted tropical & sub-tropical fruits - 

inedible peel Fatty Low Sugar

BN Fruits and Vegetables Miscellaneous Assorted tropical & sub-tropical fruits - 

inedible peel Non-fatty High Sugar

BY Cereal Grains (Low Oil) Cereal grains Cereal grains Non-fatty Low Water

BS Fruits and Vegetables Herbs & Spices Herbs & Spices

Black BC Non-fatty Low Water

Garbanzo (Chick pea) ZB Fatty Low Sugar

Garbanzo (Chick pea) 

Dried ZD Fatty Low Sugar

Kidney BC Non-fatty Low Water

Beets BT Fruits and Vegetables Root & Tuber vegs. Root & tuber vegs. Non-fatty N/A

Adipose BA

Liver BL

Muscle BM

Blackberry Fresh BK Fruits and Vegetables Berry & Small Fruit Berries & other small fruits Non-fatty Med. Sugar

Fresh BB

Frozen BZ

BR Fruits and Vegetables Brassica leafy vegs. Brassica leafy vegs. Non-fatty Low Sugar

BU Dairy Products Dairy Derived milk products Fatty Low Water

CG Fruits and Vegetables Brassica leafy vegs. Brassica leafy vegs. Non-fatty Low Sugar

CN Fruits and Vegetables Cucurbits Cucurbits Non-fatty Med. Sugar

Fresh CR Root & tuber vegs.

Baby Food IC Manufactured food single ingredient

CF Fruits and Vegetables Brassica leafy vegs. Brassica leafy vegs. Non-fatty Low Sugar

CE Fruits and Vegetables Leafy vegs. Stalk & stem vegs. Non-fatty Low Sugar

CH Fruits and Vegetables Stone fruits Stone fruits Non-fatty Med. Sugar

CL Fruits and Vegetables Herbs & Spices Herbs & Spices

Fruits and Vegetables Med. Sugar

Med. Sugar

Legume vegs.

Non-fatty

Berry & Small Fruit Berries & other small fruits Non-fatty

N/A

PAM

N/A

Commodity

Asparagus

Fruits and Vegetables

N/A Animal Tissue/High 

Protein

Non-fatty

Almonds

Barley

Non-fatty

Bananas

Fruits and Vegetables

Pinto 

Meat Meat

BC

Beef

Apples Pome fruits

Beans, canned

Low Sugar

N/A

Legume vegs.

Avocado

Basil

Cilantro

Fruits and Vegetables Root & tuber vegs.

Celery

Carrots

Blueberry

Cherries, Sweet

Cauliflower

Cantaloupe

Butter

Cabbage

Broccoli 

USDA/AMS Science Technology

Monitoring Programs Division 1

PDP QC Attachment 3

Revision 12 - Effective June 1, 2023
EPA, Codex, and Food and Drug Administration (FDA) Pesticide Analytical Manual (PAM) Commodity Groupings

PDP 

Code

PDP Commodity 

Group Commodity EPA Codex PAM

Grain CO Cereal Grains (Low Oil) Cereal grains Fatty Low Water

Sweet, Fresh CB

Sweet, Frozen CS

Sweet, Canned CD

Syrup CY Single Commodities Derived edible plant products

Fresh/Frozen CA

Canned RC

CM Dairy Products Dairy Derived milk products Fatty Low Sugar

CU Fruits and Vegetables Cucurbits Cucurbits Non-fatty Low Sugar

EG Animal Tissue/High 

Protein Miscellaneous Poultry products Non-fatty N/A

EP Fruits and Vegetables Fruiting vegs. Fruiting vegs. Non-fatty Low Sugar

FC Single Commodities or Miscellaneous Aquatic animal products Fatty No sugar

FS Animal Tissue/High 

Protein Miscellaneous Aquatic animal products Fatty No sugar

GF Fruits and Vegetables Citrus fruits Citrus fruits Non-fatty Med. Sugar

Fruit GR Berries & other small fruits High Sugar

Juice GJ Fruit juice Med. Sugar

Raw, fresh GB Legume vegs.

Baby Food IG Manufactured food single ingredient

Collard GL

Kale GK

Mustard MG

HY Single Commodities Miscellaneous Non-fatty High Sugar

HD Fruits and Vegetables Cucurbits Cucurbits Non-fatty N/A

DF Single Commodities Manufactured food multiple ingredient N/A N/A

YF Single Commodities Manufactured food multiple ingredient N/A N/A

KW Fruits and Vegetables Berry & Small Fruit Assorted tropical & sub-tropical fruits - 

inedible peel Non-fatty Med. Sugar

LM Fruits and Vegetables Citrus fruits Citrus fruits Non-fatty Low Sugar

Bunch LT

Bagged LB

MA Fruits and Vegetables Miscellaneous Assorted tropical & sub-tropical fruits - 

inedible peel Non-fatty Med. Sugar

MK Dairy Products Dairy Milks Fatty Low Sugar

MU Fruits and Vegetables Edible fungi Fruiting vegs. Non-fatty Low Sugar

NE Fruits and Vegetables Stone fruits Stone fruits Non-fatty Med. Sugar

OA Cereal Grains (Low Oil) Cereal grains Cereal grains Fatty Low Water

Fruits and Vegetables

Fruits and Vegetables

Mushrooms

Nectarines

Honey

Kiwi Fruit, Fresh

Greens

Cucumbers

Grapefruit

Grapes

Lemons

Infant formula, soy-based

Cranberry

Fruits and Vegetables

Fruits and Vegetables

Oats

Leafy vegs.

Non-fatty

Non-fatty

Berry & Small Fruit Berries & other small fruits

Med. Sugar

Non-fatty

Non-fatty

N/A

Low Sugar

Cereal grains Non-fatty

Low Sugar

Non-fatty N/A

Berry & Small Fruit 

Leafy vegs.

Brassica leafy vegs. Leafy vegs. (including Brassica leafy 

vegs.)

Legume vegs.

Low Sugar

Mangoes

Fruits and Vegetables

Milk, whole

Fish, Salmon

Honey Dew Melon

Fruits and Vegetables

Cream, heavy

Corn

Green Beans

Lettuce

Infant formula, dairy-based

Egg

Cereal grains

Eggplant

Fish, Catfish

USDA/AMS Science Technology

Monitoring Programs Division 2

PDP QC Attachment 3

Revision 12 - Effective June 1, 2023
EPA, Codex, and Food and Drug Administration (FDA) Pesticide Analytical Manual (PAM) Commodity Groupings

PDP 

Code

PDP Commodity 

Group Commodity EPA Codex PAM

Bulb ON

Green GO

Fruit OG Citrus fruits

Juice OJ Fruit juice

Frozen HZ

Canned CC

Fruit PC

Single serving CX

Baby Food IH Manufactured food single ingredient

YA Fruits and Vegetables Miscellaneous Assorted tropical & sub-tropical fruits - 

inedible peel Non-fatty Med. Sugar

PB Cereal Grains (High Oil) Miscellaneous Manufactured food single ingredient Fatty Med. Sugar

Fruit PE Pome fruits Non-fatty Med. Sugar

Juice PJ Derived edible plant products

Canned CP

Single serving PX

Baby Food IP Manufactured food single ingredient

Frozen PS

Canned SD

Baby Food IE Manufactured food single ingredient

Bell PP

Hot HP

Fruit PN

Canned NC

Dried PD

Fruit PU

Adipose KA

Muscle KM

PO Fruits and Vegetables Root & tuber vegs. Root & tuber vegs. Non-fatty Low Sugar

Adipose PA

Breast PR

Liver PL

Muscle PM

Thigh PT

Peaches Fruits and Vegetables Stone fruits Stone fruits Non-fatty Med. Sugar

Fruits and Vegetables

N/A

Non-fatty Med. Sugar

Bulb vegs. Bulb vegs.

Citrus fruits

Tropical & sub-tropical fruits - edible 

peel

Non-fatty Low Sugar

Non-fatty

Meat

Assorted tropical & sub-tropical fruits - 

inedible peel

Poultry meat

Stone fruits

Non-fatty

Meat N/A

Legume vegs.

Non-fatty Low Sugar

Fruits and Vegetables Legume vegs.

Fruits and Vegetables Stone fruits

Pineapples

Fruits and Vegetables

Peas

Peanut Butter

Fruits and Vegetables

Pome fruits

Peppers Fruits and Vegetables Fruiting vegs. Fruiting vegs.

Meat

Low Sugar

N/A N/A

Non-fatty Med. Sugar

Fruits and Vegetables

Non-fatty Med. Sugar

Tropical & subtropical fruits - 

inedible peel

Tropical & subtropical fruits - 

N/A

Pears

Olives

Orange

Papaya

Med. Sugar

Animal Tissue/High 

Protein

Animal Tissue/High 

Protein

Plums

Potatoes

Poultry

Pork

Onions

Fruit OL

Fruits and Vegetables

Pome fruits

USDA/AMS Science Technology

Monitoring Programs Division 3

PDP QC Attachment 3

Revision 12 - Effective June 1, 2023
EPA, Codex, and Food and Drug Administration (FDA) Pesticide Analytical Manual (PAM) Commodity Groupings

PDP 

Code

PDP Commodity 

Group Commodity EPA Codex PAM

Fresh RS Berries & other small fruits

Frozen RZ

RA Single Commodities Berry & Small Fruit Dried fruits Non-fatty High sugar

RI Cereal Grains (Low Oil) Cereal grains Cereal grains Non-fatty Low Sugar

SN Fruits and Vegetables Legume vegs. Legume vegs. Non-fatty Low Sugar

SY Cereal Grains (High Oil) Legume vegs. Legume vegs. Fatty Med Sugar

Leafy SP

Frozen SF

Canned SC Manufactured food single ingredient

Summer SS

Winter WS

Winter, frozen WZ

Fresh ST

Frozen SZ

Raw, fresh SW Root & tuber vegs. Root & tuber vegs. Non-fatty Med. Sugar

Baby Food IS Manufactured food single ingredient Non-fatty Med. Sugar

TA Fruits and Vegetables Citrus fruits Citrus fruits

TT Fruits and Vegetables Fruiting vegs. Fruiting vegs. N/A N/A

Cherry/Grape CT

Fresh TO

Canned TC

Paste TP Manufactured food single ingredient

Bottled WB

Drinking WR

Ground WG

Untreated WU

WM Fruits and Vegetables Cucurbits Cucurbits Non-fatty Med. Sugar

Grain WH Cereal grains

Flour WF Cereal grains, milling fraction

Non-fatty

Low Sugar

N/A

Root & tuber vegs. Root & tuber vegs. Non-fatty

Fruits and Vegetables Leafy vegs. Leafy vegs.

Raisins

Soybeans, Grain

Fruits and Vegetables

Non-fatty

Med. Sugar

Non-fatty Low Sugar

Tomatoes Fruiting vegs.

Fruiting vegs.

Tomatillos

Squash Cucurbits

Fruits and Vegetables

Fruits and Vegetables

Tangerines

Spinach

Miscellaneous N/A N/A

Fruits and Vegetables

Fruits and Vegetables

N/A

Low Sugar

N/A

Low Sugar

Non-fatty

Cucurbits

Berries & other small fruits

Radish

Wheat Cereal grains N/A

Strawberries Berry & Small Fruit 

Water

Snap Peas

RD

Rice

Watermelon

Sweet 

Potatoes

Water

Cereal Grains (Low Oil)

Non-fatty

Raspberries Fruits and Vegetables Berry & Small Fruit 

USDA/AMS Science Technology

Monitoring Programs Division 4

PDP QC Attachment 3

Revision 12 - Effective June 1, 2023
Food and Drug Administration Information for Percent Fat, Water, Sugar and pH content for Commodity Groupings 

% Fat1 % Water1 % Sugar1

pH2

Fruit 0.36 83.93 11.5 3.30 -4.00

Juice 0.11 87.93 10.9 3.35-4.00

Sauce 0.18 79.58 16.5 3.10-3.60

0.22 92.25 2.1 6.00-6.70

8.87-17.33 72.56-79.73 0.9 6.27-6.58

0.48 74.26 18.4 4.50-5.20

1.16 10.09 5.19-5.32

Black 1.42 11.02 5.78-6.02

Garbanzo (Chick pea) 6.04 11.53 3.8 6.48-6.80

Kidney 1.06 11.75 5.40-6.00

Pinto 1.13 10.95

Baby Food 0.1 92.5

0.06 92.15 5.30-6.60

0.38 84.61 7.3 3.12-3.33

0.35 90.69 1.6 6.30-6.52

81.11 17.94

0.18 92.52 2.7 5.20-6.80

0.28 89.78 8.1 6.13-6.58

0.19 87.79 6.6 5.88-6.40

0.18 92.26 2.2 5.60

0.14 94.64 1 5.70-6.00

0.96 80.76 14.6 4.01-4.54

Grain 2.08 10

Sweet 1.18 75.96 5.4 5.90-7.30

Syrup

0.2 86.54

37 57.71 2.8 6.50-6.68

0.13 96.05 2.3 5.12-5.78

0.1 91.93 3.4 5.50-6.50

4.26 76.39 0

3.4-10.44 68.5-76.35 0

0.1 90.89 6.2 3.00-3.75

Fruit 0.35 81.3 16.4 2.90-3.82

Juice 0.08 84.12 14.2

0.12 90.27 2.6 5.60

Collard 0.22 90.55

Kale 0.7 84.46 2.2 6.36-6.80

Mustard 0.2 90.8 0.8

0 17.2 81.9 3.70-4.20

0.1 89.66 6.00 - 6.67

Kiwi 0.44 83.05 8.9

0.19 95.89 1.8 5.80-6.15

0.27 81.71 14.8 3.40 - 4.80

3.66 87.69 4.9 6.40-6.80

0.42 91.81 1.8 6.00-6.70

0.46 86.28 8.5 3.92-4.18

6.9 8.22 5.9

Basil

Olives

Green Beans

Greens

Honey

Honey Dew Melon

Lettuce

Milk, whole

Mushrooms

Infant formula, dairy-based

Infant formula, soy-based

Nectarines

Oats

Mangoes

Eggplant

Fish, catfish

Grapefruit

Fish, salmon

Grapes

Corn

Cilantro

Cranberry

Cream, heavy

Cucumbers

Cantaloupe

Carrots

Cauliflower

Celery

Cherries, sweet

Blueberry

Broccoli 

Butter

Cabbage

Beets

Beans

Beef

Commodity

Almonds

Apples

Asparagus

Bananas

Barley

Avocado

USDA/AMS Science Technology

Monitoring Programs Division Page 1 of 2

PDP-QC Attachment 4

Revision 12 - Effective June 1, 2023
Food and Drug Administration Information for Percent Fat, Water, Sugar and pH content for Commodity Groupings 

% Fat1 % Water1 % Sugar1

pH2 Commodity

Bulb 0.16 89.68 4.1 5.30-5.85

Green 0.19 89.83 3.2 6.20

Fruit 0.12 86.75 8.9 3.60-4.34

Juice 0.2 88.3 10.2 3.30-4.19

0.14 88.83

0.09 87.66 8.7 3.30-4.05

49.98 1.42 7.8 6.28

Fruit 0.4 83.81 10.5 3.50-4.60

Juice 

0.4 78.86 4.5 5.70-6.70

Bell 0.19 92.19 2.5 5.20-5.93

Hot 0.2 87.74 4.65 - 5.45

0.43 86.5 11.9 3.20-4.00

0.62 85.2 7.5 2.80-4.30

 

0.1 78.96 1.0 5.40-5.90

Prunes

0.54 94.84 2.7 5.52-6.05

0.46 15.42 61.7 3.80-4.10

0.55 86.57 3.18-3.95

0.58 12.89 0.5 6.0.-6.70

19.94 8.54 6.6

0.35 91.58 0.4 5.50-6.80

Summer 0.21 93.68 2.2 5.79-6.10

Winter 0.23 88.72 2.2 5.18-6.49

0.37 91.57 5.7 3.00-3.90

0.3 72.84 5.0 5.30-5.60

0.19 87.6

Fresh 0.33 93.76 3.0 4.30-4.90

Paste 3.50-4.70

0.43 91.51 9 5.18-5.60

Grain

Flour 

1 = Pesticide Analytical Manual (PAM) data

2 = Center for Food Safety and Applied Nutrition data

Fatty (>2% fat)

Non-fatty (<2% fat)

Low H2O (<75%)

Low sugar (<5%)

Med sugar (5-15%)

Radishes

Pork

Potatoes

Poultry

Pears

Papaya

Onions

High sugar (>15%)

Spinach

Squash

Strawberries

Sweet Potatoes

Tomatoes

Watermelon

Data not avalilable

Tangerines

Rice

Soybeans

Wheat

Raspberries

Peas

Peppers

Pineapples

Plums

Raisins

Oranges

Peaches

Peanut Butter

USDA/AMS Science Technology

Monitoring Programs Division Page 2 of 2

PDP-QC Attachment 4

Revision 12 - Effective June 1, 2023
USDA, AMS Pesticide Data Program

Verification of Limits of Detection (LODs)

Commodity:

Date:

Lab:

Pesticide/Compound Amt Spk

Units = Spike 1 Spike 2

Note: During method validation, two spikes are 

required; if this form is used to record annual 

spike verification, only one spike is required.

LOD Spike Recovered 

USDA/AMS Science and Technology

Monitoring Programs Division

PDP QC Attachment 5

Revision 12 - Effective June 1, 2023
USDA, AMS Pesticide Data Program

Determination of Method Range

Commodity: Instrument/Detector:

Date: Column:

Lab:

1 X LOQ 5 X LOQ 10 X LOQ

Pesticide/Compound LOD LOQ Rep 1 Rep 2 Rep 3 Mean %CV Rep 1 Rep 2 Rep 3 Mean %CV Rep 1 Rep 2 Rep 3 Mean %CV

Units= Percent Recovery Percent Recovery Percent Recovery

USDA/AMS Science and Technology

Monitoring Programs Division

PDP QC Attachment 5

Revision 12 - Effective June 1, 2023
USDA, AMS Pesticide Data Program

Precision and Accuracy Data Collection

Commodity: Instrument/Detector:

Date: Column:

Lab:

2xLOQ Matrix Spikes

Pesticide/Compound LOD LOQ 1 2 3 4 5 6 7 Mean %CV Comments

Units= Percent Recovery %R

USDA/AMS Science and Technology

Monitoring Programs Division

PDP QC Attachment 5

Revision 12 - Effective June 1, 2023
Process Control and Spike Recovery Acceptability Flowchart

Failure to meet range

no

Investigate Problem: No further action taken

take action? at TPM's discretion;

provide explanation

yes

re-inject, re-aliquot, or re-extract?

re-extract

re-inject re-aliquot

pass

pass or fail? Report reinjection 

or re-aliquot result

fail

no

re-extract? Provide explanation of

any further action

yes

no

meet criteria? Provide explanation of

any further action

yes

Report both results

USDA/AMS Science Technology

Monitoring Programs Division

PDP QC Attachment 6

Revision 12 - Effective June 1, 2023