U.S. ENVIRONMENTAL PROTECTION ,-\GENCY 

Office of Chemical Safety and Pollution Prevention 

O ffice of Pesticide Programs 

Registration Division (7 504P) 

1200 Pennsylvania .\ve., N .\\'. 

Washington, DC 20460 

NOTICE OF PESTICIDE: 

X Registration 

Reregistration 

(Under FIFRA, as amended) 

Name and Address of Registrant (include ZIP Code): 

Arysta LifeScience North America 

15401 Weston Parkway, Suite 150 

Cary, NC 27513 

Attn: 

Rodney Akers 

EPA Reg. Date of Issuance: 

66330-404 ... SEP- 8 2014 

Date of Expiration: 

12/31/18 

Term of Issuance: 

Unconditional 

Name of Pesticide Product: 

Kasumin 2L 

Note: Changes in labeling differing in substance from that accepted in connection with this registration must be submitted to and 

accepted by the Registration Division prior to use of the label in commerce. In any correspondence on this product always refer 

to the above EPA registration number. 

On the basis of information furnished by the registrant, the above named pesticide is hereby registered 

Iunder the Federal Insecticide, Fungicide and Rodenticide Act. Registration is in no way to be 

construed as an endorsement or recommendation of this product by the Agency. In order to protect 

!health and the environment, the Administrator, on his motion, may at any time suspend or cancel the 

!registration of a pesticide in accordance with the A~t. The acceptance of any name in connection with 

the registration of a product under this Act is not to be construed as giving the registrant a right to 

exclusive use of the name or to its use if it has been covered by others. 

[This product is unconditionally registered in accordance with FIFRA section 3(c)(S), with an 

expiration date of 12/31/18, provided that you: 

1. Submit and/ or cite all data required for registration/ reregistration/ registration review of your 

product when the Agency requires all registrants of similar products to submit such data. 

2. On page 1 of the label, change the product registration number to "EPA Reg. No. 

66330-404". Also complete the Net Contents section. 

Continued on page 2 

Signature of Approving Official: Dare: 

!Hope 

~~ Johnson, Product Manager 21 

SEP- 8 20M 

Fun{!icide Branch Recistration Division (7505P) 

EPA Form 8570-6 
Notice of Pesticide Registration 

Kasumin 2L 

EPA Reg. No. 66330-404 

Page 2 of 2 

3. Submit a qualitative summary addressing release, exposure, consequence assessments and an 

overall risk estimation with regard to adverse public health effects resulting from the approved 

pome fruit registration. The qualitative summary must be submitted no earlier than six months 

before the registration expiration date and be reflective of cumulative use of kasugamycin on 

pome fruits in all states where kasugamycin is registered and used during the time-limited 

registration period. 

4. As required under FIFRA Section 6(a)(2), you are required to report information concerning 

unreasonable adverse effects, which includes information regarding resistance detection and 

misuse information to the Agency. 

5. Submit one copy of the revised final printed label for the record before you release the product 

for shipment. 

If these conditions are not complied with, the registration will be subject to cancellation in 

accordance with FIFRA section 6(e). Your release for shipment of the product constitutes 

acceptance of these conditions. Submit one copy of the revised final printed label for the 

record before the product is released for shipment. 

This registration will expire, without hearing rights, on December 31, 2018, unless the registrant 

submits an amendment to remove the time limitation. Submission of the qualitative summary 

required above in paragraph 3 is important to the Agency's evaluation an amendment to remove the 

time limitation. Thus the Agency recommends submitting such an amendment at the same time as 

the required summary and not before. Upon receipt of an amendment request, the Agency will 

review all available information and will re-evaluate:whether the registrant's product increases the 

risk of unreasonable adverse effects on public health. The Agency will attempt to issue its decision 

on the amendment request no later than the expiration date of the registration. If the Agency fails 

to make a determination on the amendment by the expiration date, the registration will remain in 

effect until the Agency makes such a determination. 

The basic CSF dated 2/23/2012 is acceptable and will be added to the regulatory file. A copy 

of the label stamped "Accepted" is enclosed for your records. If you have any questions, please 

contact Shaunta Hill at 703-347-8961 I hill.shaunta@epa.gov or Hope Johnson at 703-305-5410/ 

johnson.hope@epa.gov. ~ ~ 

Enclosures 

Hope Johnson 

Product Manager 21 

Fungicide Branch 

Registration Division (7505P) 

2 
!GROUP fjiFUNGICIDEi 

KASUMIN 2L 

For Agricultural Use Only 

For Control of Fireblight in Pome Fruit 

INGREDIENTS 

Active Ingredient 

*Kasugamycin Hydrochloride 

Hydrate ................. ..... ............. ...... ......... .... : ....... ... ........ . 

Inert Ingredients ..... .............. .............. ............ ....................... . 

Total ....... ............. ............. .................................................. . 

*(Equivalent to 2.0% kasugamycin) 

Contains 0.168 pounds kasugamycin per gallon 

KEEP OUT OF REACH OF CHILDREN 

CAUTION 

See First Aid and Additional Precautionary Statements 

For Product Information Call: 1-866-761-9397 

Bywt. 

2.3% 

97.7% 

100.0% 

EPA Reg. No. 66330-XXXXX 

Produced for: 

EPA EST. No. 075703-JPN-001 

Arysta LifeScience North America, LLC 

15401 Weston Parkway, Suite 150 

Cary, NC 27513 

AD 

NE.-:::: T--:C--:0:-:-N-:TENTS: _____ _ ACCEPTED 

SEP 0 8 2014 

Under the ederallnse~t!cide, Fungicide, and RodentJC!<i;e Act, 

as an1ended, for the p~st1c1de 

registered under 

EPA Reg No. CDt>330"' 'IC~ 

Page 1 of7 
FIRST AID 

If in eyes • Hold eye open and rinse slowly and gently with water for 15-20 

minutes. 

• Remove contact lenses, if present, after the first 5 minutes, then 

continue rinsing eye. 

• Call a poison control center or doctor for treatment advice . 

If on skin or • Take off contaminated clothing . 

clothing • Rinse skin immediately with plenty of water for 15-20 minutes . 

• Call a poison control center or doctor for treatment advice . 

If inhaled • Move person to fresh air . 

• If person is not breathing, call 911 or an ambulance, then give 

artificial respiration, preferably by mouth-to-mouth, if possible. 

• Call a poison control center or doctor for further treatment advice . 

If swallowed • Call poison control center or doctor immediately for treatment 

advice. 

• Have person sip a glass of water if able to swallow . 

• Do not induce vomiting unless told to do so by the poison control 

center or doctor. 

• Do not give anything by mouth to an unconscious person . 

Have the product container or label with you when calling a poison control center or doctor, 

or going for treatment. 

FPR 24-HOUR EMERGENCY MEDICAL ASSISTANCE: 

Call PROSAR at 1-866-303-6952 or 

1-651-632-8946 if calling from outside of the U.S. 

FOR 24-HOUR CHEMICAL EMERGENCY: Spill, leak, fire, exposure or accident, call 

CHEMTREC 1-800-424-9300 or 1-703-527-3887 if calling from outside of the U.S. 

FOR 24-HOUR EMERGENCY MEDICAL ASSISTANCE: 

CALL 1-866-303-6952 

FOR 24-HOUR CHEMICAL EMERGENCY (Spill, Leak, Fire or Accident) 

ASSISTANCE: 

CALL CHEMTREC 1-800-424-9300 

PRECAUTIONARY STATEMENTS 

HAZARDS TO HUMANS AND DOMESTIC ANIMALS 

CAUTION. Causes moderate eye irritation.· Avoid contact with eyes or clothing. Wash 

thoroughly with soap and water after handling and before eating, drinking, chewing 

gum, using tobacco or using the toilet. 

ENVIRONMENTAL HAZARDS 

For terrestrial uses: Do not apply directly to water, or to areas where surface water is 

present or to intertidal areas below the mean high water mark. Do not contaminate 

water when cleaning equipment .or disposing of equipment wash waters. 

Page 2 of7 
PERSONAL PROTECTIVE EQUIPMENT (PPE) 

Applicators and other handlers must wear long-sleeved shirt and long pants, chemical 

resistant gloves, socks and shoes. Follow the manufacturer's instructions for 

cleaning/maintaining PPE. If no such instructions for washables are available, use 

detergent and hot water. Keep and wash PPE separately from other laundry. 

USER SAFETY RECOMMENDATIONS 

Users should: 

• Wash hands before eating, drinking, chewing gum, using tobacco or using the 

toilet. 

• Remove clothing/PPE immediately if pesticide gets inside. Then wash 

thoroughly and put on clean clothing. 

• Remove PPE immediately after handling this product. Wash the outside of 

gloves before removing. As soon as possible, wash thoroughly and change 

into clean clothing. 

PRODUCT INFORMATION 

Kasumin 2L is a liquid formulation containing 2 percent kasugamycin . Kasugamycin is a 

bactericide that controls bacteria such as Erwinia amylovora, which causes fire blight in 

pome fruit. 

Resistance Management: 

Kasumin 2L (kasugamycin) is a Group 24 fungicide. The mode of action for Kasumin 2L 

is the inhibition of protein synthesis. This product should be used to treat or prevent 

infections that are proven or strongly to be caused by the indicated target bacteria. To 

reduce the likelihood of bacteria developing resistance to kasugamycin, follow the crop 

specific resistance management and use direction information present on this labeling. 

Use of this product should conform to resistance management practices I strategies 

established for the crop and use area, (for example the use of I PM, disease forecasting 

models, resistant crop varieties, etc.). Consult your local extension/crop consultant or 

State agricultural authority if reduced efficacy is suspected. 

Page 3 of 7 
AGRICULTURAL USE REQUIREMENTS 

Use this product only in accordance with its labeling and with the Worker Protection 

Standard, 40 CFR Part 170. This standard contains requirements for the protection of 

agricultural workers on farms, forests, nurseries, and greenhouses, and handlers of 

agricultural pesticides. It contains requirements for training, decontamination, 

notification, and emergency ·assistance. It also contains specific instructions and 

exceptions pertaining to the statements on the label about personal protective 

equipment (PPE) and notification to workers 

Do not enter or allow worker entry into treated areas during the restricted-entry interval 

(REI) of 12 hours. 

For early entry to treated areas that is permitted under the Worker Protection Standard 

and that involves contact with anything that has been treated , such as plants, soil, or 

water wear; coveralls, shoes, socks, and chemical resistant gloves made of any 

waterproof material, such as nitrile, butyl, neoprene, and/or barrier laminate. 

DIRECTIONS FOR USE 

It is a violation of Federal Law to use this product in a manner inconsistent with its 

labeling. 

Do not apply this product in a way that will contact workers or other persons, either 

directly or through drift. Only protected handlers may be in the area during application. 

For any requirements specific to your State or Tribe, consult the State or Tribal agency 

responsible for pesticide regulation. 

Kasumin 2L must be applied using properly calibrated , conventional ground application 

equipment appropriate for the type of crop treated. Use sufficient water volume to obtain 

thorough uniform coverage of all plant surfaces, especially open blooms. 

Additives: The addition of a wetting agent or spreader/sticker may enhance efficacy of 

Kasumin 2L. 

Page 4 of7 
POME FRUIT (APPLE AND PEAR) 

Disease 

Control 

Fire Blight 

(Erwinia 

amylovora) 

Application 

Rate to 

Use 

64 fl ozJA 

Application Timing and Resistance Management 

• Apply at a rate of 64 fl ozlA in 100 gal of water. 

Spray volume must be su.fficient to provide good 

coverage of treated foliage. 

• . Reduced spray volumes may be utilized for small 

trees where complete coverage can be obtained 

with a less than 100 gal of water/A. 

• Begin applications during bloom when conditions 

favor disease development. 

• Repeat applications at 3-6 day intervals or when 

conditions favor disease development. 

RESTRICTIONS AND OTHER INFORMATION: 

• Do not make more than 4 applications of Kasumin 2L per year 

• Do not make more than two consecutive applications of Kasumin 2 L. If 

additional antibiotic applications are needed, utilize an alternate product 

registered for this use. Two more consecutive Kasumin 2L applications 

may be made subsequent to use of the alternate registered product. 

• Do not apply more than 256 fl oz of Kasumin 2L per acre per year. 

• Do not use alternate tree-row application method 

• Do not apply more than 64 fl oz/A in a single application. 

• Do not apply after petal fall. 

• Do not apply Kasumin 2L within 90 days of harvest. 

• PHI= 90 days. 

• Do not apply kasugamycin in orchards in which the soil has been fertilized 

with animal waste/manure. 

• Animal grazing in treated areas is prohibited . The public must be notified by 

posting restriction signs along the perimeter of the treatment area. 

• Use only the specified and full strength application rates. 

Page 5 of7 
STORAGE AND DISPOSAL 

Offer for recycling if available. Do not contaminate water, food or feed by storage 

or disposal. 

PESTICIDE STORAGE: Store in a dry place away from excessive heat. Do not 

store near food or feed. Store in original container only. 

PESTICIDE DISPOSAL: Wastes resulting from the use of this product may be 

disposed of on site or at an approved waste disposal facility. 

CONTAINER HANDLING: Non-refillable container. Do not reuse or refill this 

container. 

Triple rinse container (or equivalent) promptly after emptying. Triple rinse as 

follows: Empty the remaining contents into application equipment or a mix tank 

and drain for 10 seconds after the flow begins to drip. Fill the container X full with 

water and recap. Shake for 10 seconds. Pour rinsate into application equipment 

or a mix tank or store rinsate for later use or disposal. Drain for 1 0 seconds after 

the flow begins to drip. Repeat this procedure two more times. Then offer for 

recycling or puncture and dispose of in a sanitary landfill, or (if allowed by State 

and local authorities) by burning. If burned, stay out of smoke. 

Page 6 of7 
WARRANTY AND DISCLAIMER STATEMENT 

The directions for use of this product are believed to be adequate and must be foll9wed 

carefully. However, it is impossible to eliminate all risks associated with the use of this 

product. Such risks may arise from weather conditions, . soil factors, off-target 

movement, unconventional farming techniques, the presence of other materials, the 

manner of use or application, or other unknown factors, all of which are beyond the 

control of Arysta LifeScience North America, LLC ("Arysta"), and can cause crop injury, 

injury to non-target crops or plants, ineffectiveness of the product, or other unintended 

consequences. All such risks shall be assumed by the user or buyer. 

· Arysta warrants that this product conforms to the chemical description on the label and 

is reasonably fit for the purposes stated in the Directions for Use, subject to the inherent 

risks described above, when used in accordance with the Directions for Use under 

normal conditions. This warranty does not extend to the use of this product contrary to 

label instructions or under conditions not. reasonably foreseeable to Arysta, and is 

subject to the inherent risks described above. 

TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, ARYSTA DISCLAIMS 

ALL OTHER WARRANTIES, EXPRESS OR IMPLIED, INCLUDING ANY WARRANTY 

OF MERCHANT ABILITY OR FITNESS FOR A PARTICULAR PURPOSE. TO THE 

EXTENT CONSISTENT WITH APPLICABLE LAW, ARYSTA, MANUFACTURER, 

AND SELLER DISCLAIM AND SHALL NOT BE LIABLE FOR ANY SPECIAL, 

INCIDENTAL, INDIRECT, OR CONSEQUENTIAL DAMAGES RESULTING FROM 

THE USE, HANDLING, APPLICATION, STORAGE, OR DISPOSAL OF THIS 

PRODUCT OR FOR DAMAGES IN THE NATURE OF PENAL TIES, AND THE USER 

AND BUYER WAIVE ANY RIGHT THAT THEY MAY HAVE TO SUCH DAMAGES. NO 

AGENT, REPRESENTATIVE OR EMPLOYEE OF ARYSTA IS AUTHORIZED TO 

MAKE ANY WARRANTY, GUARANTEE OR REPRESENTATION BEYOND THOSE 

CONTAINED HEREIN OR TO MODIFY THE WARRANTIES CONTAINED HEREIN. 

TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, THE EXCLUSIVE 

REMEDY OF THE USER OR BUYER, AND THE TOTAL LIABILITY OF ARYSTA, 

MANUFACTURER, AND SELLER, SHALL BE LIMITED TO THE PURCHASE PRICE 

PAID, OR AT ARYSTA'S ELECTION, THE REPLACEMENT OF THE PRODUCT. 

KASUMIN 2L (PENDING) 12/02/13, RESUBMITTED 04/16/14, RESUBMITTED 07/02/14, 

RESUBMITTED 07/21/14 RESUBMITTED 09/03/14 

Page 7 of7