|  [X] | QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 |
|-----------|-----------------------------------------------------------------------------------------|

|   | For the quarterly period ended September 30, 2012 |
|--------|---------------------------------------------------|

|  [  ] | TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 |
|-----------------|------------------------------------------------------------------------------------------|

|   | For the transition period from _____ to _____ |
|--------|-----------------------------------------------|

|                                                                               |
|------------------------------------------------------------------------------------|
| Tengion, Inc.                                                                      |
| (Exact name of registrant as specified in its charter)                             |
|  Delaware                                                                     |   | 20-0214813 |
| (State or other jurisdiction ofincorporation or organization)                      |   | (I.R.S. Employer Identification No.) |
|  3929 Westpoint Boulevard, Suite GWinston-Salem, NC 27103                     |   | (336) 722-5855 |
| (Address of principal executive offices)                                           |   | (Registrant’s telephone number,including area code) |
|  Not Applicable                                                               |
| (Former name, former address and former fiscal year, if changed since last report) |
|                                                                               |   |   |

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| EXPLANATORY NOTE                  | 1      |
|-----------------------------------|--------|
|                              |   |
| PART II – OTHER INFORMATION |   |
| Item 6.  Exhibits       | 2      |
|                              |   |
| SIGNATURES                        | 3      |

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EXPLANATORY 

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PART 

| Exhibit No. | Description                                                                                                                                                                                                   |
|-------------|---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
|        |                                                                                                                                                                                                          |
| 31.1        | Certification of John L. Miclot, President and Chief Executive Officer of the Registrant, pursuant to Section 302 of the Sarbanes-Oxley Act of 2002 (Rule 13a-14(a)/15d-14(a) certification).                 |
|        |                                                                                                                                                                                                          |
| 31.2        | Certification of A. Brian Davis, Chief Financial Officer and Vice President of Finance of the Registrant, pursuant to Section 302 of the Sarbanes-Oxley Act of 2002 (Rule 13a-14(a)/15d-14(a) certification). |

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SIGNATURES

|                             |   | TENGION, INC. |
|----------------------------------|--------|---------------|
|                             |   |          |   |   |
|                             |   |          |   |   |
| Date:  January 9, 2013 |   | By:           | /s/ John L. Miclot |
|                             |   |          |   | John L. MiclotPresident and Chief Executive Officer(Principal Executive Officer) |
|                             |   |          |   |   |
|                             |   |          |   |   |
| Date:  January 9, 2013 |   | By:           | /s/ A. Brian Davis |
|                             |   |          |   | A. Brian DavisChief Financial Officer and Vice President, Finance(Principal Financial and Accounting Officer) |
|                             |   |          |   |   |

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