Product Name: GREAT STUFF(TM) Gaps & Cracks Insulating 

Foam Sealant 12oz HC ES

Issue Date: 11/11/2011 

Print Date: 14 Nov 2011

®(TM)*Trademark

 Page 1 of 14

The Dow Chemical Company encourages and expects you to read and understand the entire (M)SDS, 

as there is important information throughout the document. We expect you to follow the precautions 

identified in this document unless your use conditions would necessitate other appropriate methods or 

actions. 

1. Product and Company Identification 

Product Name

GREAT STUFF(TM) Gaps & Cracks Insulating Foam Sealant 12oz HC ES

COMPANY IDENTIFICATION

The Dow Chemical Company 

2030 Willard H. Dow Center 

Midland, MI 48674 

USA 

Customer Information Number: 800-258-2436

EMERGENCY TELEPHONE NUMBER

24-Hour Emergency Contact: 989-636-4400 

Local Emergency Contact: 989-636-4400 

2. Hazards Identification 

Emergency Overview

Color: Yellow 

Physical State: Foam 

Odor: Mild 

Hazards of product:

DANGER! Flammable gas - May cause flash fire. May cause allergic skin reaction. 

May cause allergic respiratory reaction. May cause eye irritation. May cause skin 

irritation. Vapor reduces oxygen available for breathing. May cause anesthetic 

effects. May cause respiratory tract irritation. Vapors may travel a long distance; 

ignition and/or flash back may occur. May cause lung injury. May be harmful if 

swallowed. Evacuate area. Keep upwind of spill. Stay out of low areas. Aerosol cans 

exposed to fire can rupture becoming flaming projectiles. Elevated temperatures can 

cause hazardous polymerization. Toxic fumes may be released in fire situations. 

Containers are under high pressure. Avoid temperatures above 50°C (122°F) 

OSHA Hazard Communication Standard

Material Safety Data Sheet

The Dow Chemical Company
Product Name: GREAT STUFF(TM) Gaps & Cracks Insulating 

Foam Sealant 12oz HC ES

Issue Date: 11/11/2011 

Page 2 of 14

This product is a "Hazardous Chemical" as defined by the OSHA Hazard Communication Standard, 29 

CFR 1910.1200. 

Potential Health Effects

Eye Contact: May cause eye irritation. May cause slight temporary corneal injury. 

Skin Contact: Prolonged contact may cause moderate skin irritation with local redness. Material may 

stick to skin causing irritation upon removal. May stain skin. 

Skin Absorption: Prolonged skin contact is unlikely to result in absorption of harmful amounts. 

Skin Sensitization: Skin contact may cause an allergic skin reaction. Animal studies have shown that 

skin contact with isocyanates may play a role in respiratory sensitization. 

Inhalation: In confined or poorly ventilated areas, vapor can easily accumulate and can cause 

unconsciousness and death due to displacement of oxygen. Excessive exposure may cause irritation 

to upper respiratory tract (nose and throat) and lungs. May cause pulmonary edema (fluid in the 

lungs.) Effects may be delayed. May cause central nervous system depression. Symptoms of 

excessive exposure may be anesthetic or narcotic effects; dizziness and drowsiness may be 

observed. Excessive exposure may increase sensitivity to epinephrine and increase myocardial 

irritability (irregular heartbeats). Decreased lung function has been associated with overexposure to 

isocyanates. 

Respiratory Sensitization: May cause allergic respiratory response. MDI concentrations below the 

exposure guidelines may cause allergic respiratory reactions in individuals already sensitized. 

Asthma-like symptoms may include coughing, difficult breathing and a feeling of tightness in the chest. 

Occasionally, breathing difficulties may be life threatening. 

Ingestion: Low toxicity if swallowed. Small amounts swallowed incidentally as a result of normal 

handling operations are not likely to cause injury; however, swallowing larger amounts may cause 

injury. Observations in animals include: Gastrointestinal irritation. 

Aspiration hazard: Based on physical properties, not likely to be an aspiration hazard. 

Effects of Repeated Exposure: Tissue injury in the upper respiratory tract and lungs has been 

observed in laboratory animals after repeated excessive exposures to MDI/polymeric MDI aerosols. 

Excessive exposure may produce organophosphate type cholinesterase inhibition. Signs and 

symptoms of excessive exposure may be headache, dizziness, incoordination, muscle twitching, 

tremors, nausea, abdominal cramps, diarrhea, sweating, pinpoint pupils, blurred vision, salivation, 

tearing, tightness in chest, excessive urination, convulsions. 

Cancer Information: Lung tumors have been observed in laboratory animals exposed to respirable 

aerosol droplets of MDI/Polymeric MDI (6 mg/m3) for their lifetime. Tumors occurred concurrently with 

respiratory irritation and lung injury. Current exposure guidelines are expected to protect against these 

effects reported for MDI. 

Birth Defects/Developmental Effects: In laboratory animals, MDI/polymeric MDI did not cause birth 

defects; other fetal effects occurred only at high doses which were toxic to the mother. 

Component CAS # Amount 

Methyl ether 115-10-6 >= 1.0 - <= 5.0 %

Propane 74-98-6 >= 1.0 - <= 5.0 %

Paraffin waxes and Hydrocarbon waxes, chlorinated 63449-39-8 >= 5.0 - <= 10.0 %

Isobutane 75-28-5 >= 7.0 - <= 13.0 %

Isocyanic acid, polymethylenepolyphenylene ester, 

polymer with .alpha.,.alpha.',.alpha.''-1,2,3-

propanetriyltris[.omega.-hydroxypoly

57029-46-6 >= 30.0 - <= 60.0 %

Polymethylenepolyphenyl polyisocyanate, 

polypropyleneglycol copolymer

53862-89-8 >= 10.0 - <= 30.0 %

Diphenylmethane Diisocyanate, isomers and homologues 9016-87-9 >= 10.0 - <= 30.0 %

Tris(1-chloro-2-propyl) phosphate 13674-84-5 >= 5.0 - <= 10.0 %

4,4' -Methylenediphenyl diisocyanate 101-68-8 >= 5.0 - <= 10.0 %

Note: CAS 101-68-8 is an MDI isomer that is part of CAS 9016-87-9. 

3. Composition Information
Product Name: GREAT STUFF(TM) Gaps & Cracks Insulating 

Foam Sealant 12oz HC ES

Issue Date: 11/11/2011 

Page 3 of 14

4. First-aid measures 

Description of first aid measures

General advice: First Aid responders should pay attention to self-protection and use the 

recommended protective clothing (chemical resistant gloves, splash protection). If potential for 

exposure exists refer to Section 8 for specific personal protective equipment. 

Inhalation: Move person to fresh air. If not breathing, give artificial respiration; if by mouth to mouth 

use rescuer protection (pocket mask, etc). If breathing is difficult, oxygen should be administered by 

qualified personnel. Call a physician or transport to a medical facility. 

Skin Contact: Remove material from skin immediately by washing with soap and plenty of water. 

Remove contaminated clothing and shoes while washing. Seek medical attention if irritation persists. 

Wash clothing before reuse. An MDI skin decontamination study demonstrated that cleaning very 

soon after exposure is important, and that a polyglycol-based skin cleanser or corn oil may be more 

effective than soap and water. Discard items which cannot be decontaminated, including leather 

articles such as shoes, belts and watchbands. Suitable emergency safety shower facility should be 

available in work area. 

Eye Contact: Immediately flush eyes with water; remove contact lenses, if present, after the first 5 

minutes, then continue flushing eyes for at least 15 minutes. Obtain medical attention without delay, 

preferably from an ophthalmologist. Suitable emergency eye wash facility should be immediately 

available. 

Ingestion: If swallowed, seek medical attention. Do not induce vomiting unless directed to do so by 

medical personnel. 

Most important symptoms and effects, both acute and delayed

Aside from the information found under Description of first aid measures (above) and Indication of 

immediate medical attention and special treatment needed (below), no additional symptoms and 

effects are anticipated.

Indication of immediate medical attention and special treatment needed

Maintain adequate ventilation and oxygenation of the patient. May cause respiratory sensitization or 

asthma-like symptoms. Bronchodilators, expectorants and antitussives may be of help. Treat 

bronchospasm with inhaled beta2 agonist and oral or parenteral corticosteroids. Respiratory 

symptoms, including pulmonary edema, may be delayed. Persons receiving significant exposure 

should be observed 24-48 hours for signs of respiratory distress. Exposure may increase "myocardial 

irritability". Do not administer sympathomimetic drugs such as epinephrine unless absolutely 

necessary. If you are sensitized to diisocyanates, consult your physician regarding working with other 

respiratory irritants or sensitizers. Although cholinesterase depression has been reported with this 

material, it is not of benefit in determining exposure and need not be considered in the treatment of 

persons exposed to the material. Treatment of exposure should be directed at the control of 

symptoms and the clinical condition of the patient. 

Excessive exposure may aggravate preexisting asthma and other respiratory disorders (e.g. 

emphysema, bronchitis, reactive airways dysfunction syndrome). Repeated excessive exposure may 

aggravate preexisting lung disease. 

5. Fire Fighting Measures 

Suitable extinguishing media

Water fog or fine spray. Dry chemical fire extinguishers. Carbon dioxide fire extinguishers. Foam. 

Alcohol resistant foams (ATC type) are preferred. General purpose synthetic foams (including AFFF) 

or protein foams may function, but will be less effective. 

Extinguishing Media to Avoid: Do not use direct water stream. Straight or direct water streams may 

not be effective to extinguish fire. 

Special hazards arising from the substance or mixture
Product Name: GREAT STUFF(TM) Gaps & Cracks Insulating 

Foam Sealant 12oz HC ES

Issue Date: 11/11/2011 

Page 4 of 14

Hazardous Combustion Products: During a fire, smoke may contain the original material in addition 

to combustion products of varying composition which may be toxic and/or irritating. Combustion 

products may include and are not limited to: Nitrogen oxides. Isocyanates. Hydrogen chloride. 

Carbon monoxide. Carbon dioxide. Hydrogen cyanide. 

Unusual Fire and Explosion Hazards: Contains flammable propellant. Aerosol cans exposed to fire 

can rupture and become flaming projectiles. Propellant release may result in a fireball. Vapors are 

heavier than air and may travel a long distance and accumulate in low lying areas. Ignition and/or flash 

back may occur. Dense smoke is produced when product burns. 

Advice for firefighters

Fire Fighting Procedures: Keep people away. Isolate fire and deny unnecessary entry. Stay 

upwind. Keep out of low areas where gases (fumes) can accumulate. Water may not be effective in 

extinguishing fire. Do not use direct water stream. May spread fire. Fight fire from protected location 

or safe distance. Consider the use of unmanned hose holders or monitor nozzles. Eliminate ignition 

sources. Move container from fire area if this is possible without hazard. Use water spray to cool fireexposed containers and fire-affected zone until fire is out. 

Special Protective Equipment for Firefighters: Wear positive-pressure self-contained breathing 

apparatus (SCBA) and protective fire fighting clothing (includes fire fighting helmet, coat, trousers, 

boots, and gloves). Avoid contact with this material during fire fighting operations. If contact is likely, 

change to full chemical resistant fire fighting clothing with self-contained breathing apparatus. If this is 

not available, wear full chemical resistant clothing with self-contained breathing apparatus and fight fire 

from a remote location. For protective equipment in post-fire or non-fire clean-up situations, refer to 

the relevant sections. 

6. Accidental Release Measures 

Personal precautions, protective equipment and emergency procedures: Evacuate area. Only 

trained and properly protected personnel must be involved in clean-up operations. Keep personnel out 

of low areas. Keep personnel out of confined or poorly ventilated areas. Keep upwind of spill. 

Ventilate area of leak or spill. No smoking in area. For large spills, warn public of downwind explosion 

hazard. Check area with combustible gas detector before reentering area. Ground and bond all 

containers and handling equipment. Eliminate all sources of ignition in vicinity of spill or released 

vapor to avoid fire or explosion. Vapor explosion hazard. Keep out of sewers. See Section 10 for 

more specific information. Use appropriate safety equipment. For additional information, refer to 

Section 8, Exposure Controls and Personal Protection. Refer to Section 7, Handling, for additional 

precautionary measures. 

Environmental precautions: Prevent from entering into soil, ditches, sewers, waterways and/or 

groundwater. See Section 12, Ecological Information. 

Methods and materials for containment and cleaning up: Contain spilled material if possible. 

Ground and bond all containers and handling equipment. Isolate area until gas has dispersed. Use 

non-sparking tools in cleanup operations. Eliminate all sources of ignition in vicinity of spill or released 

vapor to avoid fire or explosion. Check area with combustible gas detector before reentering area. 

Ground and bond all containers and handling equipment. Collect in suitable and properly labeled 

containers. Absorb with materials such as: Clay. Dirt. Milsorb®. Sand. Sawdust. Vermiculite. See 

Section 10 for more specific information. See Section 13, Disposal Considerations, for additional 

information. 

7. Handling and Storage 

Handling 

General Handling: Keep away from heat, sparks and flame. Avoid contact with eyes. Avoid contact 

with skin and clothing. Avoid prolonged or repeated contact with skin. Avoid breathing vapor. Wash 

thoroughly after handling. Keep container closed. Use only with adequate ventilation. Keep out of 
Product Name: GREAT STUFF(TM) Gaps & Cracks Insulating 

Foam Sealant 12oz HC ES

Issue Date: 11/11/2011 

Page 5 of 14

reach of children. No smoking, open flames or sources of ignition in handling and storage area. 

Vapors are heavier than air and may travel a long distance and accumulate in low lying areas. Ignition 

and/or flash back may occur. Contents under pressure. Do not puncture or incinerate container. 

Containers, even those that have been emptied, can contain vapors. Do not cut, drill, grind, weld, or 

perform similar operations on or near empty containers. Do not enter confined spaces unless 

adequately ventilated. Never use air pressure for transferring product. Use of non-sparking or 

explosion-proof equipment may be necessary, depending upon the type of operation. See Section 8, 

EXPOSURE CONTROLS AND PERSONAL PROTECTION. 

Storage 

Minimize sources of ignition, such as static build-up, heat, spark or flame. Store in a dry place. See 

Section 10 for more specific information. 

Shelf life: Use within Storage temperature: 

12 Months 20 - 30 °C 

8. Exposure Controls / Personal Protection 

Exposure Limits

Component List Type Value |

4,4' -Methylenediphenyl 

diisocyanate

ACGIH TWA 0.005 ppm 

OSHA Table 

Z-1

Ceiling 0.2 mg/m3 0.02 ppm 

|

Diphenylmethane 

Diisocyanate, isomers and 

homologues

ACGIH TWA 0.005 ppm 

OSHA Table 

Z-1

Ceiling 0.2 mg/m3 0.02 ppm 

|

Methyl ether AIHA WEEL TWA 1,880 mg/m3 1,000 ppm |

Isobutane ACGIH TWA 1,000 ppm |

Propane OSHA Table 

Z-1

PEL 1,800 mg/m3 1,000 ppm 

ACGIH TWA 1,000 ppm |

Personal Protection

Eye/Face Protection: Use safety glasses (with side shields). 

Skin Protection: Use protective clothing chemically resistant to this material. Selection of specific 

items such as face shield, boots, apron, or full body suit will depend on the task. 

Hand protection: Use gloves chemically resistant to this material. Examples of preferred 

glove barrier materials include: Butyl rubber. Chlorinated polyethylene. Polyethylene. Ethyl 

vinyl alcohol laminate ("EVAL"). Examples of acceptable glove barrier materials include: 

Neoprene. Nitrile/butadiene rubber ("nitrile" or "NBR"). Viton. Polyvinyl chloride ("PVC" or 

"vinyl"). NOTICE: The selection of a specific glove for a particular application and duration of 

use in a workplace should also take into account all relevant workplace factors such as, but 

not limited to: Other chemicals which may be handled, physical requirements (cut/puncture 

protection, dexterity, thermal protection), potential body reactions to glove materials, as well as 

the instructions/specifications provided by the glove supplier. 

Respiratory Protection: Atmospheric levels should be maintained below the exposure guideline. 

When atmospheric levels may exceed the exposure guideline, use an approved air-purifying respirator 

equipped with an organic vapor sorbent and a particle filter. For situations where the atmospheric 

levels may exceed the level for which an air-purifying respirator is effective, use a positive-pressure 

air-supplying respirator (air line or self-contained breathing apparatus). For emergency response or 

for situations where the atmospheric level is unknown, use an approved positive-pressure selfcontained breathing apparatus or positive-pressure air line with auxiliary self-contained air supply. In 
Product Name: GREAT STUFF(TM) Gaps & Cracks Insulating 

Foam Sealant 12oz HC ES

Issue Date: 11/11/2011 

Page 6 of 14

confined or poorly ventilated areas, use an approved self-contained breathing apparatus or positive 

pressure air line with auxiliary self-contained air supply. The following should be effective types of airpurifying respirators: Organic vapor cartridge with a particulate pre-filter. 

Ingestion: Use good personal hygiene. Do not consume or store food in the work area. Wash hands 

before smoking or eating. 

Engineering Controls

Ventilation: Use only with adequate ventilation. Local exhaust ventilation may be necessary for some 

operations. Provide general and/or local exhaust ventilation to control airborne levels below the 

exposure guidelines. Exhaust systems should be designed to move the air away from the source of 

vapor/aerosol generation and people working at this point. The odor and irritancy of this material are 

inadequate to warn of excessive exposure. Lethal concentrations may exist in areas with poor 

ventilation. 

9. Physical and Chemical Properties 

Appearance

 Physical State Foam 

 Color Yellow 

Odor Mild 

Odor Threshold No test data available

pH Not applicable

Melting Point No test data available

Freezing Point No test data available

Boiling Point (760 mmHg) Not applicable. 

Flash Point - Closed Cup -104 °C (-155 °F) Calculated 

Evaporation Rate (Butyl 

Acetate = 1)

No test data available

Flammability (solid, gas) No 

Flammable Limits In Air Lower: No test data available 

Upper: No test data available 

Vapor Pressure 1,151 kPa @ 55 °C Container is under pressure. 

Vapor Density (air = 1) No test data available

Specific Gravity (H2O = 1) 1.06 Estimated. 

Solubility in water (by 

weight)

Insoluble

Partition coefficient, noctanol/water (log Pow)

No data available for this product. See Section 12 for individual 

component data.

Autoignition Temperature No test data available

Decomposition 

Temperature

No test data available

Kinematic Viscosity Not applicable

Explosive properties Not explosive 

Oxidizing properties No 

10. Stability and Reactivity 

Reactivity

No dangerous reaction known under conditions of normal use.

Chemical stability

Stable under recommended storage conditions. See Storage, Section 7. Unstable at elevated 

temperatures. 

Possibility of hazardous reactions

Can occur. Elevated temperatures can cause hazardous polymerization. 
Product Name: GREAT STUFF(TM) Gaps & Cracks Insulating 

Foam Sealant 12oz HC ES

Issue Date: 11/11/2011 

Page 7 of 14

Conditions to Avoid: Avoid temperatures above 50 °C (122 °F). Elevated temperatures can cause 

container to vent and/or rupture. Exposure to elevated temperatures can cause product to 

decompose. 

Incompatible Materials: Avoid contact with: Acids. Alcohols. Amines. Ammonia. Bases. Metal 

compounds. Strong oxidizers. Products based on diisocyanates like TDI and MDI react with many 

materials to release heat. The reaction rate increases with temperature as well as with increased 

contact; these reactions can become violent. Contact is increased by stirring or if the other material 

acts as a solvent. Products based on diisocyanates such as TDI and MDI are not soluble in water and 

will sink to the bottom, but react slowly at the interface. The reaction forms carbon dioxide gas and a 

layer of solid polyurea. Reaction with water will generate carbon dioxide and heat. 

Hazardous decomposition products

Decomposition products depend upon temperature, air supply and the presence of other materials. 

Toxic gases are released during decomposition. 

11. Toxicological Information 

Acute Toxicity 

Ingestion 

As product: Single dose oral LD50 has not been determined. 

Estimated. LD50, rat > 2,000 mg/kg

Dermal 

As product: The dermal LD50 has not been determined. 

Estimated. LD50, rabbit > 2,000 mg/kg

Inhalation 

As product: The LC50 has not been determined. 

Eye damage/eye irritation

May cause eye irritation. May cause slight temporary corneal injury. 

Skin corrosion/irritation

Prolonged contact may cause moderate skin irritation with local redness. Material may stick to skin 

causing irritation upon removal. May stain skin. 

Sensitization

Skin 

Skin contact may cause an allergic skin reaction. Animal studies have shown that skin contact with 

isocyanates may play a role in respiratory sensitization. 

Respiratory

May cause allergic respiratory response. MDI concentrations below the exposure guidelines may 

cause allergic respiratory reactions in individuals already sensitized. Asthma-like symptoms may 

include coughing, difficult breathing and a feeling of tightness in the chest. Occasionally, breathing 

difficulties may be life threatening. 

Repeated Dose Toxicity

Tissue injury in the upper respiratory tract and lungs has been observed in laboratory animals after 

repeated excessive exposures to MDI/polymeric MDI aerosols. Excessive exposure may produce 

organophosphate type cholinesterase inhibition. Signs and symptoms of excessive exposure may be 

headache, dizziness, incoordination, muscle twitching, tremors, nausea, abdominal cramps, diarrhea, 

sweating, pinpoint pupils, blurred vision, salivation, tearing, tightness in chest, excessive urination, 

convulsions. 

Chronic Toxicity and Carcinogenicity 

Lung tumors have been observed in laboratory animals exposed to respirable aerosol droplets of 

MDI/Polymeric MDI (6 mg/m3) for their lifetime. Tumors occurred concurrently with respiratory 

irritation and lung injury. Current exposure guidelines are expected to protect against these effects 

reported for MDI. 

Developmental Toxicity

In laboratory animals, MDI/polymeric MDI did not cause birth defects; other fetal effects occurred only 

at high doses which were toxic to the mother. 

Reproductive Toxicity

No relevant information found. 
Product Name: GREAT STUFF(TM) Gaps & Cracks Insulating 

Foam Sealant 12oz HC ES

Issue Date: 11/11/2011 

Page 8 of 14

Genetic Toxicology 

In vitro genetic toxicity studies were negative for component(s) tested. Genetic toxicity data on MDI 

are inconclusive. MDI was weakly positive in some in vitro studies; other in vitro studies were negative. 

Animal mutagenicity studies were predominantly negative. 

12. Ecological Information 

Toxicity

Data for Component: Methyl ether

Material is practically non-toxic to aquatic organisms on an acute basis 

(LC50/EC50/EL50/LL50 >100 mg/L in the most sensitive species tested). 

Fish Acute & Prolonged Toxicity 

LC50, guppy (Poecilia reticulata), semi-static test, 96 h: > 4,000 mg/l

Aquatic Invertebrate Acute Toxicity 

LC50, water flea Daphnia magna, 48 h, immobilization: > 4,000 mg/l 

Data for Component: Propane

No relevant data found. 

Data for Component: Paraffin waxes and Hydrocarbon waxes, chlorinated

Material is very highly toxic to aquatic organisms on an acute basis (LC50/EC50 <0.1 mg/L in 

the most sensitive species). 

Fish Acute & Prolonged Toxicity 

LC50, rainbow trout (Oncorhynchus mykiss), static, 96 h: > 100 mg/l

Aquatic Invertebrate Acute Toxicity 

EC50, water flea Daphnia magna, static test, 48 h, immobilization: 0.037 mg/l 

Data for Component: Isobutane

No relevant data found. 

Data for Component: Isocyanic acid, polymethylenepolyphenylene ester, polymer with 

.alpha.,.alpha.',.alpha.''-1,2,3-propanetriyltris[.omega.-hydroxypoly

Not expected to be acutely toxic to aquatic organisms. 

Data for Component: Polymethylenepolyphenyl polyisocyanate, polypropyleneglycol copolymer

Not expected to be acutely toxic to aquatic organisms. 

Data for Component: Diphenylmethane Diisocyanate, isomers and homologues

The measured ecotoxicity is that of the hydrolyzed product, generally under conditions 

maximizing production of soluble species. Material is practically non-toxic to aquatic 

organisms on an acute basis (LC50/EC50/EL50/LL50 >100 mg/L in the most sensitive species 

tested). 

Fish Acute & Prolonged Toxicity 

Based on information for a similar material: LC50, Danio rerio (zebra fish), static, 96 h: > 

1,000 mg/l

Aquatic Invertebrate Acute Toxicity 

Based on information for a similar material: EC50, water flea Daphnia magna, static test, 24 

h: > 1,000 mg/l

Aquatic Plant Toxicity 

Based on information for a similar material: NOEC, Scenedesmus subspicatus (new name: 

Desmodesmus subspicatus), static test, Growth rate inhibition, 72 h: 1,640 mg/l

Toxicity to Micro-organisms 

Based on information for a similar material: EC50; activated sludge, static, 3 h: > 100 mg/l

Toxicity to Soil Dwelling Organisms 

EC50, Eisenia fetida (earthworms), 14 d: > 1,000 mg/kg 

Data for Component: Tris(1-chloro-2-propyl) phosphate

Material is not classified as dangerous to aquatic organisms. 
Product Name: GREAT STUFF(TM) Gaps & Cracks Insulating 

Foam Sealant 12oz HC ES

Issue Date: 11/11/2011 

Page 9 of 14

Fish Acute & Prolonged Toxicity 

LC50, Lepomis macrochirus (Bluegill sunfish), static, 96 h: 84 mg/l

Aquatic Invertebrate Acute Toxicity 

EC50, water flea Daphnia magna, 48 h, immobilization: 131 mg/l

Aquatic Plant Toxicity 

ErC50, Pseudokirchneriella subcapitata (green algae), static test, Growth rate inhibition, 96 h: 

82 mg/l

Toxicity to Micro-organisms 

EC50, OECD 209 Test; activated sludge, Respiration inhibition, 3 h: 784 mg/l

Aquatic Invertebrates Chronic Toxicity Value 

water flea Daphnia magna, semi-static test, 21 d, number of offspring, NOEC: 32 mg/l 

Data for Component: 4,4' -Methylenediphenyl diisocyanate

The measured ecotoxicity is that of the hydrolyzed product, generally under conditions 

maximizing production of soluble species. Material is practically non-toxic to aquatic 

organisms on an acute basis (LC50/EC50/EL50/LL50 >100 mg/L in the most sensitive species 

tested). 

Fish Acute & Prolonged Toxicity 

Based on information for a similar material: LC50, Danio rerio (zebra fish), static, 96 h: > 

1,000 mg/l

Aquatic Invertebrate Acute Toxicity 

Based on information for a similar material: EC50, water flea Daphnia magna, static test, 24 

h: > 1,000 mg/l

Aquatic Plant Toxicity 

Based on information for a similar material: NOEC, Scenedesmus subspicatus (new name: 

Desmodesmus subspicatus), static test, Growth rate inhibition, 72 h: 1,640 mg/l

Toxicity to Micro-organisms 

Based on information for a similar material: EC50; activated sludge, static, 3 h: > 100 mg/l

Toxicity to Soil Dwelling Organisms 

EC50, Eisenia fetida (earthworms), 14 d: > 1,000 mg/kg 

Persistence and Degradability 

Data for Component: Methyl ether

Material is expected to biodegrade only very slowly (in the environment). Fails to pass 

OECD/EEC tests for ready biodegradability. 

OECD Biodegradation Tests: 

Biodegradation Exposure Time Method 10 Day Window

5 % 28 d OECD 301A Test fail

Indirect Photodegradation with OH Radicals

Rate Constant Atmospheric Half-life Method

1.66E-12 cm3/s 6.4 d Estimated.

Theoretical Oxygen Demand: 2.08 mg/mg

Data for Component: Propane

No relevant data found. 

Indirect Photodegradation with OH Radicals

Rate Constant Atmospheric Half-life Method

1.27E-12 cm3/s 8.4 d Estimated.

Theoretical Oxygen Demand: 3.64 mg/mg

Data for Component: Paraffin waxes and Hydrocarbon waxes, chlorinated

Expected to degrade only slowly in the environment. 

Theoretical Oxygen Demand: 2.89 mg/mg

Data for Component: Isobutane

Biodegradation may occur under aerobic conditions (in the presence of oxygen). 

Indirect Photodegradation with OH Radicals
Product Name: GREAT STUFF(TM) Gaps & Cracks Insulating 

Foam Sealant 12oz HC ES

Issue Date: 11/11/2011 

Page 10 of 14

Rate Constant Atmospheric Half-life Method

2.44E-12 cm3/s 4.4 d Estimated.

Theoretical Oxygen Demand: 3.58 mg/mg

Data for Component: Isocyanic acid, polymethylenepolyphenylene ester, polymer with 

.alpha.,.alpha.',.alpha.''-1,2,3-propanetriyltris[.omega.-hydroxypoly

Expected to degrade only slowly in the environment. 

Data for Component: Polymethylenepolyphenyl polyisocyanate, polypropyleneglycol copolymer

Expected to degrade only slowly in the environment. 

Data for Component: Diphenylmethane Diisocyanate, isomers and homologues

In the aquatic and terrestrial environment, material reacts with water forming predominantly 

insoluble polyureas which appear to be stable. In the atmospheric environment, material is 

expected to have a short tropospheric half-life, based on calculations and by analogy with 

related diisocyanates. 

OECD Biodegradation Tests: Based on information for a similar material: 

Biodegradation Exposure Time Method 10 Day Window

0 % 28 d OECD 302C Test Not applicable

Data for Component: Tris(1-chloro-2-propyl) phosphate

Material is expected to biodegrade only very slowly (in the environment). Fails to pass 

OECD/EEC tests for ready biodegradability. 

OECD Biodegradation Tests: 

Biodegradation Exposure Time Method 10 Day Window

14 % 28 d OECD 301E Test fail

95 % 64 d OECD 302A Test

Indirect Photodegradation with OH Radicals

Rate Constant Atmospheric Half-life Method

4.47E-11 cm3/s 0.24 d Estimated.

Theoretical Oxygen Demand: 1.17 mg/mg

Data for Component: 4,4' -Methylenediphenyl diisocyanate

In the aquatic and terrestrial environment, material reacts with water forming predominantly 

insoluble polyureas which appear to be stable. In the atmospheric environment, material is 

expected to have a short tropospheric half-life, based on calculations and by analogy with 

related diisocyanates. 

OECD Biodegradation Tests: Based on information for a similar material: 

Biodegradation Exposure Time Method 10 Day Window

0 % 28 d OECD 302C Test Not applicable

Bioaccumulative potential 

Data for Component: Methyl ether

Bioaccumulation: Bioconcentration potential is low (BCF < 100 or Log Pow < 3). 

Partition coefficient, n-octanol/water (log Pow): 0.10 Measured 

Data for Component: Propane

Bioaccumulation: Bioconcentration potential is low (BCF < 100 or Log Pow < 3). 

Partition coefficient, n-octanol/water (log Pow): 2.36 Measured 

Data for Component: Paraffin waxes and Hydrocarbon waxes, chlorinated

Bioaccumulation: Bioconcentration potential is low (BCF less than 100 or log Pow greater 

than 7). 

Partition coefficient, n-octanol/water (log Pow): 7.4 Estimated. 

Data for Component: Isobutane

Bioaccumulation: Bioconcentration potential is low (BCF < 100 or Log Pow < 3). 

Partition coefficient, n-octanol/water (log Pow): 2.76 Measured 
Product Name: GREAT STUFF(TM) Gaps & Cracks Insulating 

Foam Sealant 12oz HC ES

Issue Date: 11/11/2011 

Page 11 of 14

Data for Component: Isocyanic acid, polymethylenepolyphenylene ester, polymer with 

.alpha.,.alpha.',.alpha.''-1,2,3-propanetriyltris[.omega.-hydroxypoly

Bioaccumulation: In the aquatic and terrestrial environment, movement is expected to be 

limited by its reaction with water forming predominantly insoluble polyureas. 

Data for Component: Polymethylenepolyphenyl polyisocyanate, polypropyleneglycol copolymer

Bioaccumulation: In the aquatic and terrestrial environment, movement is expected to be 

limited by its reaction with water forming predominantly insoluble polyureas. 

Data for Component: Diphenylmethane Diisocyanate, isomers and homologues

Bioaccumulation: In the aquatic and terrestrial environment, movement is expected to be 

limited by its reaction with water forming predominantly insoluble polyureas. 

Data for Component: Tris(1-chloro-2-propyl) phosphate

Bioaccumulation: Bioconcentration potential is low (BCF < 100 or Log Pow < 3). 

Partition coefficient, n-octanol/water (log Pow): 2.59 Measured 

Bioconcentration Factor (BCF): 0.8 - 4.6; common carp (Cyprinus carpio); Measured 

Data for Component: 4,4' -Methylenediphenyl diisocyanate

Bioaccumulation: In the aquatic and terrestrial environment, movement is expected to be 

limited by its reaction with water forming predominantly insoluble polyureas. 

Mobility in soil 

Data for Component: Methyl ether

Mobility in soil: Potential for mobility in soil is very high (Koc between 0 and 50). 

Partition coefficient, soil organic carbon/water (Koc): 1.29 - 14 Estimated.

Henry's Law Constant (H): 9.78E-04 atm*m3/mole; 25 °C Measured 

Data for Component: Propane

Mobility in soil: Potential for mobility in soil is very high (Koc between 0 and 50). 

Partition coefficient, soil organic carbon/water (Koc): 24 - 460 Estimated.

Henry's Law Constant (H): 7.07E-01 atm*m3/mole; 25 °C Measured 

Distribution in Environment: Mackay Level 1 Fugacity Model: 

Air Water. Biota Soil Sediment

100 % 0 % 0 % 0 % 0 %

Data for Component: Paraffin waxes and Hydrocarbon waxes, chlorinated

Mobility in soil: Given its very low Henry's constant, volatilization from natural bodies of water 

or moist soil is not expected to be an important fate process., Expected to be relatively 

immobile in soil (Koc > 5000). 

Partition coefficient, soil organic carbon/water (Koc): > 5,000 Estimated.

Henry's Law Constant (H): < 1.0E-07 atm*m3/mole; 25 °C Estimated. 

Data for Component: Isobutane

Mobility in soil: Potential for mobility in soil is very high (Koc between 0 and 50). 

Partition coefficient, soil organic carbon/water (Koc): 35 Estimated.

Henry's Law Constant (H): 1.19E+00 atm*m3/mole; 25 °C Measured 

Distribution in Environment: Mackay Level 1 Fugacity Model: 

Air Water. Biota Soil Sediment

100 % 0 % 0 % 0 % 0 %

Data for Component: Isocyanic acid, polymethylenepolyphenylene ester, polymer with 

.alpha.,.alpha.',.alpha.''-1,2,3-propanetriyltris[.omega.-hydroxypoly

Mobility in soil: In the aquatic and terrestrial environment, movement is expected to be 

limited by its reaction with water forming predominantly insoluble polyureas. 

Data for Component: Polymethylenepolyphenyl polyisocyanate, polypropyleneglycol copolymer

Mobility in soil: In the aquatic and terrestrial environment, movement is expected to be 

limited by its reaction with water forming predominantly insoluble polyureas. 

Data for Component: Diphenylmethane Diisocyanate, isomers and homologues

Mobility in soil: In the aquatic and terrestrial environment, movement is expected to be 

limited by its reaction with water forming predominantly insoluble polyureas. 

Data for Component: Tris(1-chloro-2-propyl) phosphate

Mobility in soil: Potential for mobility in soil is slight (Koc between 2000 and 5000). 

Partition coefficient, soil organic carbon/water (Koc): 1,300 Estimated.

Henry's Law Constant (H): < 1.35E-05 atm*m3/mole; 25 °C Estimated. 

Data for Component: 4,4' -Methylenediphenyl diisocyanate

Mobility in soil: In the aquatic and terrestrial environment, movement is expected to be 

limited by its reaction with water forming predominantly insoluble polyureas. 
Product Name: GREAT STUFF(TM) Gaps & Cracks Insulating 

Foam Sealant 12oz HC ES

Issue Date: 11/11/2011 

Page 12 of 14

13. Disposal Considerations 

DO NOT DUMP INTO ANY SEWERS, ON THE GROUND, OR INTO ANY BODY OF WATER. All 

disposal practices must be in compliance with all Federal, State/Provincial and local laws and 

regulations. Regulations may vary in different locations. Waste characterizations and compliance with 

applicable laws are the responsibility solely of the waste generator. AS YOUR SUPPLIER, WE HAVE 

NO CONTROL OVER THE MANAGEMENT PRACTICES OR MANUFACTURING PROCESSES OF 

PARTIES HANDLING OR USING THIS MATERIAL. THE INFORMATION PRESENTED HERE 

PERTAINS ONLY TO THE PRODUCT AS SHIPPED IN ITS INTENDED CONDITION AS 

DESCRIBED IN MSDS SECTION: Composition Information. FOR UNUSED & UNCONTAMINATED 

PRODUCT, the preferred options include sending to a licensed, permitted: Incinerator or other 

thermal destruction device. 

14. Transport Information 

DOT Non-Bulk

 

CONSUMER COMMODITY RECLASSIFIED AS ORM-D MATERIAL 

DOT Bulk

NOT AVAILABLE IN BULK CONTAINERS 

IMDG

Proper Shipping Name: AEROSOLS 

Hazard Class: 2.1 ID Number: UN1950 

EMS Number: F-D,S-U 

Marine pollutant.: Yes

 

LIMITED QUANTITY 

ICAO/IATA

Proper Shipping Name: AEROSOLS, FLAMMABLE 

Hazard Class: 2.1 ID Number: UN1950Cargo Packing Instruction: 203 

Passenger Packing Instruction: 203 

 

LIMITED QUANTITY 

Additional Information

 

MARINE POLLUTANT (Paraffin waxes and Hydrocarbon waxes, chlorinated) 

This information is not intended to convey all specific regulatory or operational 

requirements/information relating to this product. Additional transportation system information can be 

obtained through an authorized sales or customer service representative. It is the responsibility of the 

transporting organization to follow all applicable laws, regulations and rules relating to the 

transportation of the material. 

15. Regulatory Information 

OSHA Hazard Communication Standard

This product is a "Hazardous Chemical" as defined by the OSHA Hazard Communication Standard, 29 

CFR 1910.1200. 
Product Name: GREAT STUFF(TM) Gaps & Cracks Insulating 

Foam Sealant 12oz HC ES

Issue Date: 11/11/2011 

Page 13 of 14

Superfund Amendments and Reauthorization Act of 1986 Title III (Emergency Planning 

and Community Right-to-Know Act of 1986) Sections 311 and 312

Immediate (Acute) Health Hazard Yes 

Delayed (Chronic) Health Hazard Yes 

Fire Hazard Yes 

Reactive Hazard No 

Sudden Release of Pressure Hazard Yes 

Superfund Amendments and Reauthorization Act of 1986 Title III (Emergency Planning and 

Community Right-to-Know Act of 1986) Section 313

This product contains the following substances which are subject to the reporting requirements of 

Section 313 of Title III of the Superfund Amendments and Reauthorization Act of 1986 and which are 

listed in 40 CFR 372. 

Component CAS # Amount

4,4' -Methylenediphenyl diisocyanate 101-68-8 >= 5.0 - <= 10.0 %

Diphenylmethane Diisocyanate, isomers and 

homologues 

9016-87-9 >= 10.0 - <= 30.0 %

Pennsylvania (Worker and Community Right-To-Know Act): Pennsylvania Hazardous 

Substances List and/or Pennsylvania Environmental Hazardous Substance List:

The following product components are cited in the Pennsylvania Hazardous Substance List and/or the 

Pennsylvania Environmental Substance List, and are present at levels which require reporting. 

Component CAS # Amount

4,4' -Methylenediphenyl diisocyanate 101-68-8 >= 5.0 - <= 10.0 %

Methyl ether 115-10-6 >= 1.0 - <= 5.0 %

Propane 74-98-6 >= 1.0 - <= 5.0 %

Isobutane 75-28-5 >= 7.0 - <= 13.0 %

Pennsylvania (Worker and Community Right-To-Know Act): Pennsylvania Special Hazardous 

Substances List:

To the best of our knowledge, this product does not contain chemicals at levels which require reporting 

under this statute. 

California Proposition 65 (Safe Drinking Water and Toxic Enforcement Act of 1986)

This product contains no listed substances known to the State of California to cause cancer, birth 

defects or other reproductive harm, at levels which would require a warning under the statute. 

US. Toxic Substances Control Act

All components of this product are on the TSCA Inventory or are exempt from TSCA Inventory 

requirements under 40 CFR 720.30 

CEPA - Domestic Substances List (DSL)

All substances contained in this product are listed on the Canadian Domestic Substances List (DSL) or 

are not required to be listed. 

16. Other Information 

Recommended Uses and Restrictions

Identified uses 

Polyurethane foam. 

Revision 

Identification Number: 63953 / 0000 / Issue Date 11/11/2011 / Version: 4.0 

Most recent revision(s) are noted by the bold, double bars in left-hand margin throughout this 

document. 
Product Name: GREAT STUFF(TM) Gaps & Cracks Insulating 

Foam Sealant 12oz HC ES

Issue Date: 11/11/2011 

Page 14 of 14

Legend 

N/A Not available 

W/W Weight/Weight 

OEL Occupational Exposure Limit 

STEL Short Term Exposure Limit 

TWA Time Weighted Average 

ACGIH American Conference of Governmental Industrial Hygienists, Inc. 

DOW IHG Dow Industrial Hygiene Guideline 

WEEL Workplace Environmental Exposure Level 

HAZ_DES Hazard Designation 

Action Level A value set by OSHA that is lower than the PEL which will trigger the need for 

activities such as exposure monitoring and medical surveillance if exceeded. 

The Dow Chemical Company urges each customer or recipient of this (M)SDS to study it carefully and 

consult appropriate expertise, as necessary or appropriate, to become aware of and understand the 

data contained in this (M)SDS and any hazards associated with the product. The information herein is 

provided in good faith and believed to be accurate as of the effective date shown above. However, no 

warranty, express or implied, is given. Regulatory requirements are subject to change and may differ 

between various locations. It is the buyer's/user's responsibility to ensure that his activities comply with 

all federal, state, provincial or local laws. The information presented here pertains only to the product 

as shipped. Since conditions for use of the product are not under the control of the manufacturer, it is 

the buyer's/user's duty to determine the conditions necessary for the safe use of this product. Due to 

the proliferation of sources for information such as manufacturer-specific (M)SDSs, we are not and 

cannot be responsible for (M)SDSs obtained from any source other than ourselves. If you have 

obtained an (M)SDS from another source or if you are not sure that the (M)SDS you have is current, 

please contact us for the most current version.