Federal Register / Vol. 77, No. 69 / Tuesday, April 10, 2012 / Notices 21573 

related to the priority area of Education 

and Community-Based Programs. 

Potential applicants may download a 

copy of Healthy People 2020, at http:// 

www.healthypeople.gov. 

Interested individuals are reminded 

that the list of eligible health and allied 

professions is effective for applicants for 

the 2012–2013 academic year. These 

priorities will remain in effect until 

superseded. Applicants who apply for 

health career categories not listed as 

priorities during the current scholarship 

cycle will not be considered for a 

scholarship award. 

Dated: April 4, 2012. 

Randy Grinnell, 

Deputy Director, Indian Health Service. 

[FR Doc. 2012–8517 Filed 4–9–12; 8:45 am] 

BILLING CODE 4165–16–P 

DEPARTMENT OF HEALTH AND 

HUMAN SERVICES 

National Institutes of Health 

Government-Owned Inventions; 

Availability for Licensing 

AGENCY: National Institutes of Health, 

Public Health Service, HHS. 

ACTION: Notice. 

SUMMARY: The inventions listed below 

are owned by an agency of the U.S. 

Government and are available for 

licensing in the U.S. in accordance with 

35 U.S.C. 207 to achieve expeditious 

commercialization of results of 

federally-funded research and 

development. Foreign patent 

applications are filed on selected 

inventions to extend market coverage 

for companies and may also be available 

for licensing. 

ADDRESSES: Licensing information and 

copies of the U.S. patent applications 

listed below may be obtained by writing 

to the indicated licensing contact at the 

Office of Technology Transfer, National 

Institutes of Health, 6011 Executive 

Boulevard, Suite 325, Rockville, 

Maryland 20852–3804; telephone: 301– 

496–7057; fax: 301–402–0220. A signed 

Confidential Disclosure Agreement will 

be required to receive copies of the 

patent applications. 

Nonpathogenic Bacteria, Paenibacillus 

alvei, Useful as a Natural Biocontrol 

Agent for Elimination of Food-borne 

Pathogenic Bacteria 

Description of Technology: This 

newly isolated non-pathogenic bacterial 

strain (TS–15) has shown the ability kill 

or inhibit a wide variety of harmful 

bacteria including many of the most 

common food-borne pathogens such as 

Salmonella, Escherichia, Listeria, 

Shigella, Enterobacter and 

Staphylococcus. The TS–15 strain may 

provide a natural low cost means to 

help protect the food supply. The strain 

may be used as a biocontrol agent in the 

form of a pesticide or pretreatment to 

soils in which fruits and vegetable are 

grown. Preventative use of the TS–15 

strain in biocontrol measures may 

prevent many of the millions of 

illnesses in the U.S. that are caused by 

food-borne pathogens each year. Such 

prevention may also reduce the 

associated costs of treatment for such 

illnesses. Furthermore, isolation and 

development of the antibiotic 

compounds produced by the TS–15 

strain may yield useful new 

compositions to help treat bacterial 

illness, including infections by some 

pathogens resistant to standard 

antibiotics. 

Potential Commercial Applications 

• Agriculture—pesticide. 

• Medicine—antibiotic. 

Competitive Advantages: Low cost 

natural means of prevention of many 

food-borne bacterial illnesses. 

Development Stage: Early-stage. 

Inventors: Eric Brown (FDA), Jie 

Zheng (FDA), and Alex Enurah. 

Intellectual Property: HHS Reference 

No. E–042–2011/0—U.S. Provisional 

Application No. 61/488,271 filed 20 

May 2011. 

Licensing Contact: Tedd Fenn; 301– 

435–5031; Tedd.Fenn@nih.gov. 

Collaborative Research Opportunity: 

The FDA Center for Food Safety and 

Applied Nutrition is seeking statements 

of capability or interest from parties 

interested in collaborative research to 

further develop, evaluate or 

commercialize Paenibacillus alvei (TS– 

15). For collaboration opportunities, 

please contact Alice Welch at 

alice.welch@fda.hhs.gov. 

Glass Capillary Arrays for Calibration, 

Validation, and Quality Assurance of 

Quantitative Measurements from 

Diffusion MRI Applications 

Description of Technology: NIH 

scientists have developed a tool for 

calibration and quality assurance for 

diffusion MRI applications. These Glass 

Capillary Arrays (GCAs) allow reliable 

means for instrument calibration and 

data measurement validation of various 

MRI scanning parameters. A variety of 

GCA conformations is available, so they 

have broad utility in MRI applications 

ranging from material sciences to 

clinical and biological MRI. 

Potential Commercial Applications 

• Calibration, quality assurance, and 

quality control for diffusion MRI 

applications using physics and 

mathematics algorithms combined with 

known GCA properties. 

• GCAs come in various diameters 

and thicknesses, so can be utilized in a 

wide range of sciences (material and 

biological). 

• Provides known standards for 

adjustment of various parameters, 

including magnetic field gradient, 

magnetic field homogeneity, and 

radiofrequency pulse. 

Competitive Advantages 

• Allows sufficient quality assurance 

and instrument calibration not 

previously available for advanced 

diffusion MRI. 

• GCAs are non-toxic and biologically 

and environmentally safe, so can be 

stored without special permits or 

requirements. 

Development Stage: Prototype. 

Inventors: Ferenc Horkey, et al. 

(NICHD). 

Intellectual Property: HHS Reference 

No. E–202–2010/0—U.S. Provisional 

Application No. 61/536,032 filed 18 Sep 

2011. 

Licensing Contact: John Stansberry, 

Ph.D.; 301–435–5236; 

stansbej@mail.nih.gov. 

Diffusion MRI of Beating Hearts and 

Other Moving Tissues in Live Patients 

Description of Technology: Diffusion 

Tensor Imaging (DTI) is an improved 

form of Magnetic Resonance Imaging 

(MRI) that provides microscopic details 

about tissue structure based on water 

diffusion. DTI is commonly used to 

visualize the brain when examining 

patients with neurological disorders or 

strokes. Currently, DTI faces technical 

limitations preventing imaging of 

moving tissues, such as the beating 

heart, spinal cord, and base of the brain. 

The NIH inventors have established an 

improved method allowing application 

of DTI to moving tissues. Using DTI to 

examine patients’ hearts will allow for 

better detection of location and severity 

of ischemia and for probing general 

muscle structure and integrity. This 

method can be applied to various 

diffusion models including Diffusion 

Weighted Imaging (DWI). 

Potential Commercial Applications 

• Heart disease diagnosis. 

• Evaluating new drugs for effects on 

heart. 

• Planning surgical procedures. 

• Imaging spinal cord, base of brain, 

and periventricular zones. 

• Enhanced imaging of other tissues. 


srobinson on DSK4SPTVN1PROD with NOTICES
21574 Federal Register / Vol. 77, No. 69 / Tuesday, April 10, 2012 / Notices 

Competitive Advantages 

• Application of state-of-the-art DTI 

to a wider range of tissues. 

• Works with multiple diffusion 

models including DWI. 

Development Stage: Early-stage. 

Inventor: Peter J. Basser (NICHD). 

Publication: Rohde G, et al. 

Comprehensive approach for correction 

of motion and distortion in diffusionweighted MRI. Magn Reson Med. 2004 

Jan;51(1):103–114. [PMID 14705050] 

Intellectual Property: HHS Reference 

No. E–168–2009/0—U.S. Provisional 

Application No. 61/523,108 filed 12 

Aug 2011. 

Related Technologies 

• HHS Reference No. E–203–1993/ 

0—U.S. Patent No. 5,539,310 issued 23 

Jul 1996; PCT Application No. PCT/ 

US94/08842 filed 05 Aug 1994. 

• HHS Reference No. E–079–2003/1 

—U.S. Application No. 12/114,713 filed 

02 May 2008. 

• HHS Reference No. E–079–2003/0 

—U.S. Patent No. 7,643,863 issued 05 

Jan 2010; PCT Application No. PCT/ 

US2004/22027 filed 08 Jul 2004. 

Licensing Contact: John Stansberry, 

Ph.D.; 301–435–5236; 

stansbej@mail.nih.gov. 

Dated: April 4, 2012. 

Richard U. Rodriguez, 

Director, Division of Technology Development 

and Transfer, Office of Technology Transfer, 

National Institutes of Health. 

[FR Doc. 2012–8577 Filed 4–9–12; 8:45 am] 

BILLING CODE 4140–01–P 

DEPARTMENT OF HEALTH AND 

HUMAN SERVICES 

National Institutes of Health 

Prospective Grant of Exclusive 

License: Method for Segmenting 

Medical Images and Detecting Surface 

Anomalies in Anatomical Structures 

AGENCY: National Institutes of Health, 

Public Health Service, HHS. 

ACTION: Notice. 

SUMMARY: This is notice, in accordance 

with 35 U.S.C. 209(c)(1) and 37 CFR 

404.7(a)(1)(i), that the National 

Institutes of Health (NIH), Department 

of Health and Human Services, is 

contemplating the grant of an exclusive 

license to practice the inventions 

embodied in U.S. Patents: 6,246,784 

filed August 18, 1998 and issued June 

12, 2001; 6,345,112 filed January 19, 

2001 and issued February 5, 2002; and 

6,556,696 filed February 5, 2002 and 

issued April 29, 2003; each entitled 

‘‘Method for segmenting medical images 

and detecting surface anomalies in 

anatomical structures,’’ by Ronald M. 

Summers et al., to iCAD, Inc. having a 

place of business in 98 Spit Brook Road, 

Suite 100, Nashua, NH 03062 USA. The 

patent rights in this invention have been 

assigned to the United States of 

America. 

DATES: Only written comments and/or 

application for a license that are 

received by the NIH Office of 

Technology Transfer on or before May 

10, 2012 will be considered. 

ADDRESSES: Requests for a copy of the 

patent application, inquiries, comments 

and other materials relating to the 

contemplated license should be directed 

to: Tedd Fenn, Office of Technology 

Transfer, National Institutes of Health, 

6011 Executive Boulevard, Suite 325, 

Rockville, MD 20852–3804; Email: 

Tedd.Fenn@mail.nih.gov; Telephone: 

301–435–5031; Facsimile: 301–402– 

0220. 

SUPPLEMENTARY INFORMATION: The 

invention relates to methods of 

processing medical image data to extract 

information about organ structure and 

reconstruct the anatomical image in a 

virtual 3D model to detect anomalies. 

The methods help solve imaging 

problems such as image ‘‘leakage,’’ 

which causes distortion, overloads 

datasets and slows the 3D modeling 

display. Once the image is assembled, 

additional processing methods can 

detect surface anomalies by comparing 

the curvature characteristics of anatomy 

to curvature characteristics anomalies. 

The anomalies in the image can be 

colorized or otherwise identified in the 

image to enhance detection. This is 

helpful to identify harmful features such 

as precancerous polyps or other 

anomalies. 

The field of use may be limited to 

‘‘computer aided detection in 

colonography.’’ 

The prospective worldwide exclusive 

license will be royalty bearing and will 

comply with the terms and conditions 

of 35 U.S.C. 209 and 37 CFR 404.7. The 

prospective exclusive license may be 

granted unless, within thirty (30) days 

from the date of this published Notice, 

NIH receives written evidence and 

argument that establishes that the grant 

of the license would not be consistent 

with the requirements of 35 U.S.C. 209 

and 37 CFR 404.7. 

Properly filed competing applications 

for a license filed in response to this 

notice will be treated as objections to 

the contemplated license. Comments 

and objections submitted in response to 

this notice will not be made available 

for public inspection, and, to the extent 

permitted by law, will not be released 

under the Freedom of Information Act, 

5 U.S.C. 552. 

Dated: April 4, 2012. 

Richard U. Rodriguez, 

Director, Division of Technology Development 

& Transfer, Office of Technology Transfer, 

National Institutes of Health. 

[FR Doc. 2012–8578 Filed 4–9–12; 8:45 am] 

BILLING CODE 4140–01–P 

DEPARTMENT OF HOMELAND 

SECURITY 

Federal Emergency Management 

Agency 

[Docket ID FEMA–2011–0039; OMB No. 

1660–0124] 

Agency Information Collection 

Activities: Submission for OMB 

Review; Comment Request, FEMA 

Preparedness Grants: Emergency 

Operations Center (EOC) Grant 

Program 

AGENCY: Federal Emergency 

Management Agency, DHS. 

ACTION: Notice. 

SUMMARY: The Federal Emergency 

Management Agency (FEMA) will 

submit the information collection 

abstracted below to the Office of 

Management and Budget for review and 

clearance in accordance with the 

requirements of the Paperwork 

Reduction Act of 1995. The submission 

will describe the nature of the 

information collection, the categories of 

respondents, the estimated burden (i.e., 

the time, effort and resources used by 

respondents to respond) and cost, and 

the actual data collection instruments 

FEMA will use. 

DATES: Comments must be submitted on 

or before May 10, 2012. 

ADDRESSES: Submit written comments 

on the proposed information collection 

to the Office of Information and 

Regulatory Affairs, Office of 

Management and Budget. Comments 

should be addressed to the Desk Officer 

for the Department of Homeland 

Security, Federal Emergency 

Management Agency, and sent via 

electronic mail to 

oira.submission@omb.eop.gov or faxed 

to (202) 395–5806. 

FOR FURTHER INFORMATION CONTACT: 

Requests for additional information or 

copies of the information collection 

should be made to Director, Records 

Management Division, 1800 South Bell 

Street, Arlington, VA 20598–3005, 

facsimile number (202) 646–3347, or 

email address FEMA–InformationCollections-Management@dhs.gov. 


srobinson on DSK4SPTVN1PROD with NOTICES