Exhibit 4.1

    Form of Indenture

    MEDIWOUND LTD.

    and

    INDENTURE

    Dated as of ________, _____

     

    

    TABLE OF CONTENTS

     

    

    	
            ARTICLE I DEFINITIONS AND INCORPORATION BY REFERENCE

          	
            1

          
	 	 
	
            Section 1.01 Definitions

          	
            1

          
	
            Section 1.02 Other Definitions

          	
            4

          
	
            Section 1.03 Incorporation by Reference of Trust Indenture Act

          	
            4

          
	
            Section 1.04 Rules of Construction

          	
            4

          
	 	 
	
            ARTICLE II THE SECURITIES

          	
            5

          
	 	 
	
            Section 2.01 Issuable in Series

          	
            5

          
	
            Section 2.02 Establishment of Terms of Series of Securities

          	
            5

          
	
            Section 2.03 Execution and Authentication

          	
            6

          
	
            Section 2.04 Registrar and Paying Agent

          	
            7

          
	
            Section 2.05 Paying Agent to Hold Money in Trust

          	
            7

          
	
            Section 2.06 Holder Lists

          	
            7

          
	
            Section 2.07 Transfer and Exchange

          	
            7

          
	
            Section 2.08 Mutilated, Destroyed, Lost and Stolen Securities

          	
            7

          
	
            Section 2.09 Outstanding Securities

          	
            8

          
	
            Section 2.10 Treasury Securities

          	
            8

          
	
            Section 2.11 Temporary Securities

          	
            8

          
	
            Section 2.12 Cancellation

          	
            8

          
	
            Section 2.13 Defaulted Interest

          	
            8

          
	
            Section 2.14 Global Securities

          	
            9

          
	
            Section 2.15 CUSIP Numbers

          	
            9

          
	 	 
	
            ARTICLE III REDEMPTION

          	
            10

          
	 	 
	
            Section 3.01 Notice to Trustee

          	
            10

          
	
            Section 3.02 Selection of Securities to be Redeemed

          	
            10

          
	
            Section 3.03 Notice of Redemption

          	
            10

          
	
            Section 3.04 Effect of Notice of Redemption

          	
            10

          
	
            Section 3.05 Deposit of Redemption Price

          	
            11

          
	
            Section 3.06 Securities Redeemed in Part

          	
            11

          


     

    i

    

    
      
        


    

    

    	
            ARTICLE IV COVENANTS

          	
            11

          
	 	 
	
            Section 4.01 Payment of Principal and Interest

          	
            11

          
	
            Section 4.02 SEC Reports

          	
            11

          
	
            Section 4.03 Compliance Certificate

          	
            11

          
	
            Section 4.04 Stay, Extension and Usury Laws

          	
            11

          
	 	 
	
            ARTICLE V SUCCESSORS

          	
            12

          
	 	 
	
            Section 5.01 When Company May Merge, Etc.

          	
            12

            

          
	
            Section 5.02 Successor Corporation Substituted

          	
            12

          
	 	 
	
            ARTICLE VI DEFAULTS AND REMEDIES

          	 
	 	 
	
            Section 6.01 Events of Default

          	
            13

          
	
            Section 6.02 Acceleration of Maturity; Rescission and Annulment

          	
            13

          
	
            Section 6.03 Collection of Indebtedness and Suits for Enforcement by Trustee

          	
            14

          
	
            Section 6.04 Trustee May File Proofs of Claim

          	
            14

          
	
            Section 6.05 Trustee May Enforce Claims Without Possession of Securities

          	
            15

          
	
            Section 6.06 Application of Money Collected

          	
            15

          
	
            Section 6.07 Limitation on Suits

          	
            15

          
	
            Section 6.08 Unconditional Right of Holders to Receive Principal and Interest

          	
            16

          
	
            Section 6.09 Restoration of Rights and Remedies

          	
            16

          
	
            Section 6.10 Rights and Remedies Cumulative

          	
            16

          
	
            Section 6.11 Delay or Omission Not Waiver

          	
            16

          
	
            Section 6.12 Control by Holders

          	
            16

          
	
            Section 6.13 Waiver of Past Defaults

          	
            16

          
	
            Section 6.14 Undertaking for Costs

          	
            16

          
	 	 
	
            ARTICLE VII TRUSTEE

          	
            17

          
	 	 
	
            Section 7.01 Duties of Trustee

          	
            17

          
	
            Section 7.02 Rights of Trustee

          	
            18

          
	
            Section 7.03 Individual Rights of Trustee

          	
            18

          
	
            Section 7.04 Trustee’s Disclaimer

          	
            18

          
	
            Section 7.05 Notice of Defaults

          	
            18

          
	
            Section 7.06 Reports by Trustee to Holders

          	
            19

          
	
            Section 7.07 Compensation and Indemnity

          	
            19

          
	
            Section 7.08 Replacement of Trustee

          	
            19

          
	
            Section 7.09 Successor Trustee by Merger, etc.

          	
            19

          
	
            Section 7.10 Eligibility; Disqualification

          	
            19

          
	
            Section 7.11 Preferential Collection of Claims Against Company

          	
            19

          


    

    

    ii

    

    
      
        


    

    

    

    

    	 	 
	
            ARTICLE VIII SATISFACTION AND DISCHARGE; DEFEASANCE

          	
            20

            

          
	 	 
	
            Section 8.01 Satisfaction and Discharge of Indenture

          	
            20

            

          
	
            Section 8.02 Application of Trust Funds; Indemnification

          	
            20

            

          
	
            Section 8.03 Legal Defeasance of Securities of any Series

          	
            21

          
	
            Section 8.04 Covenant Defeasance

          	
            22

          
	
            Section 8.05 Repayment to Company

          	
            22

          
	
            Section 8.06 Reinstatement

          	
            22

          
	 	 
	
            ARTICLE IX AMENDMENTS AND WAIVERS

          	
            23

          
	 	 
	
            Section 9.01 Without Consent of Holders

          	
            23

          
	
            Section 9.02 With Consent of Holders

          	
            24

          
	
            Section 9.03 Limitations

          	
            24

          
	
            Section 9.04 Compliance with Trust Indenture Act

          	
            24

          
	
            Section 9.05 Revocation and Effect of Consents

          	
            24

          
	
            Section 9.06 Notation on or Exchange of Securities

          	
            24

          
	
            Section 9.07 Trustee Protected

             

            

          	
            24

          
	
            ARTICLE X MISCELLANEOUS

          	
            25

          
	 	 
	
            Section 10.01 Trust Indenture Act Controls

          	
            25

          
	
            Section 10.02 Notices.

          	
            25

          
	
            Section 10.03 Communication by Holders with Other Holders

          	
            25

          
	
            Section 10.04 Certificate and Opinion as to Conditions Precedent

          	
            25

          
	
            Section 10.05 Statements Required in Certificate or Opinion

          	
            26

          
	
            Section 10.06 Rules by Trustee and Agents

          	
            26

          
	
            Section 10.07 Legal Holidays

          	
            26

          
	
            Section 10.08 No Recourse Against Others

          	
            26

          
	
            Section 10.09 Counterparts

          	
            26

          
	
            Section 10.10 Governing Laws

          	
            26

          
	
            Section 10.11 No Adverse Interpretation of Other Agreements

          	
            26

          
	
            Section 10.12 Successors

          	
            26

          
	
            Section 10.13 Severability

          	
            26

          
	
            Section 10.14 Table of Contents, Headings, Etc.

          	
            26

          
	
            Section 10.15 Securities in a Foreign Currency

          	
            26

          
	
            Section 10.16 Judgment Currency

          	
            26

          
	 	 
	
            ARTICLE XI SINKING FUNDS

          	
            27

          
	 	 
	
            Section 11.01 Applicability of Article

          	
            27

          
	
            Section 11.02 Satisfaction of Sinking Fund Payments with Securities

          	
            27

          
	
            Section 11.03 Redemption of Securities for Sinking Fund

          	
            28

          


     

    iii

    

    
      
        


    

    

      

      

      MEDIWOUND LTD.

    Reconciliation and tie between Trust Indenture Act of 1939 and

    Indenture, dated as of_______, ____

     

    

    	
            Section 310

          	
            (a)(1)

          	
            7.10

          
	 	
            (a)(2)

          	
            7.10

          
	 	
            (a)(3)

          	
            NOT APPLICABLE

          
	 	
            (a)(4)

          	
            NOT APPLICABLE

          
	 	
            (a)(5)

          	
            7.10

          
	 	
            (b)

          	
            7.10

          
	
            Section 311

          	
            (a)

          	
            7.11

          
	 	
            (b)

          	
            7.11

          
	 	
            (c)

          	
            NOT APPLICABLE

          
	
            Section 312

          	
            (a)

          	
            2.06

          
	 	
            (b)

          	
            10.03

          
	 	
            (c)

          	
            10.03

          
	
            Section 313

          	
            (a)

          	
            7.06

          
	 	
            (b)

          	
            7.06

          
	 	
            (c)

          	
            7.06

          
	 	
            (d)

          	
            7.06

          
	
            Section 314

          	
            (a)

          	
            4.02

          
	 	
            (a)(4)

          	
            10.05

          
	 	
            (b)

          	
            NOT APPLICABLE

          
	 	
            (c)

          	
            NOT APPLICABLE

          
	 	
            (d)

          	
            NOT APPLICABLE

          
	 	
            (e)

          	
            10.05

          
	 	
            (f)

          	
            NOT APPLICABLE

          


     

    

    Indenture dated as of________,______ between MediWound Ltd., an Israeli company (“Company”), and_______, a_______ corporation, as trustee
      (“ Trustee ”).

     

    

    Each party agrees as follows for the benefit of the other party and for the equal and ratable benefit of the Holders of the Securities issued under this Indenture.

     

    iv

    

    
      
        


    

    
    

    

    

    ARTICLE I

    DEFINITIONS AND INCORPORATION BY REFERENCE

     

    

    Section 1.01 Definitions.

     

    

    
      “Additional Amounts” means any additional amounts which are required hereby or by any
        Security, under circumstances specified herein or therein, to be paid by the Company in respect of certain taxes imposed on Holders specified herein or therein and which are owing to such Holders.

       

      “Affiliate” of any specified person means any other person directly or indirectly
        controlling or controlled by or under direct or indirect common control with such specified person. For the purposes of this definition, “control” (including, with correlative meanings, the terms “controlled by” and “under common control with”), as
        used with respect to any person, shall mean the possession, directly or indirectly, of the power to direct or cause the direction of the management or policies of such person, whether through the ownership of voting securities or by agreement or
        otherwise.

       

      “Agent” means any Registrar, Paying Agent or Service Agent.

       

      “Applicable Procedures” means, with respect to any transfer or transaction involving a
        Global Security or beneficial interest therein, the rules and procedures of DTC or any successor Depositary, in each case to the extent applicable to such transaction and as in effect from time to time.

       

      “Authorized Newspaper” means a newspaper in an official language of the country of
        publication customarily published at least once a day for at least five days in each calendar week and of general circulation in the place in connection with which the term is used. If it shall be impractical in the opinion of the Trustee to make
        any publication of any notice required hereby in an Authorized Newspaper, any publication or other notice in lieu thereof that is made or given by the Trustee shall constitute a sufficient publication of such notice.

       

      “Bearer” means anyone in possession from time to time of a Bearer Security.

       

      “Bearer Security” means any Security, including any interest coupon appertaining thereto,
        that does not provide for the identification of the Holder thereof.

       

      “Board of Directors” means the Board of Directors of the Company or any duly authorized
        committee thereof.

       

      “Board Resolution” means a copy of a resolution certified by the Secretary or an
        Assistant Secretary of the Company to have been adopted by the Board of Directors or pursuant to authorization by the Board of Directors and to be in full force and effect on the date of the certificate and delivered to the Trustee.

       

      “Business Day” means, unless otherwise provided by Board Resolution, Officers’
        Certificate or supplemental indenture hereto for a particular Series, any day except a Saturday, Sunday or a legal holiday in The City of New York on which banking institutions are authorized or required by law, regulation or executive order to
        close.

       

      “Capital Interests” means any and all shares, interests, participations, rights or other
        equivalents (however designated) of capital stock, including, without limitation, with respect to partnerships, partnership interests (whether general or limited) and any other interest or participation that confers on a person the right to receive
        a share of the profits and losses of, or distributions of assets of, such partnership.

       

      

       

      
        1

        
          


      

       

      “Company” means the party named as such above until a successor replaces it and
        thereafter means the successor.

       

      “Company Order” means a written order signed in the name of the Company by two Officers,
        one of whom must be the Company’s principal executive officer, principal financial officer or principal accounting officer.

       

      “Company Request” means a written request signed in the name of the Company by its Chief
        Executive Officer, Chief Financial Officer or a Vice President, and by its Treasurer, an Assistant Treasurer, its Secretary or an Assistant Secretary, and delivered to the Trustee.

       

      “Corporate Trust Office” means the office of the Trustee at which at any particular time
        its corporate trust business shall be principally administered.

       

      “Default” means any event which is, or after notice or passage of time or both would be,
        an Event of Default.

       

      “Depository” means, with respect to the Securities of any Series issuable or issued in
        whole or part in the form of one or more Global Securities, the person designated as Depositary for such Series by the Company, which Depository shall be a clearing agency registered under the Exchange Act; and if at any time there is more than one
        such person, “Depository” as used with respect to the Securities of any Series shall mean the Depository with respect to the Securities of such Series.

       

      “Discount Security” means any Security that provides for an amount less than the stated
        principal amount thereof to be due and payable upon declaration of acceleration of the maturity thereof pursuant to Section 6.02.

       

      “Dollars” and “$” means the currency of The
        United States of America.

       

      “DTC” means the Depository Trust Company, a New York corporation.

       

      “Exchange Act” means the Securities Exchange Act of 1934, as amended, and the rules and
        regulations promulgated thereunder.

       

      “Foreign Currency” means any currency or currency unit issued by a government other than
        the government of The United States of America.

       

      “Foreign Government Obligations” means, with respect to Securities of any Series that are
        denominated in a Foreign Currency, (i) direct obligations of the government that issued or caused to be issued such currency for the payment of which obligations its full faith and credit is pledged or (ii) obligations of a person controlled or
        supervised by or acting as an agency or instrumentality of such government the timely payment of which is unconditionally guaranteed as a full faith and credit obligation by such government, which, in either case under clauses (i) or (ii), are not
        callable or redeemable at the option of the issuer thereof.

       

      “GAAP” means generally accepted accounting principles set forth in the opinions and
        pronouncements of the Accounting Principles Board of the American Standards Board or in such other statements by such other entity as have been approved by a significant segment of the accounting profession.

       

      “Global Security” or “Global Securities” means a
        Security or Securities, as the case may be, in the form established pursuant to Section 2.02 evidencing all or part of a Series of Securities, issued to the Depository for such Series or its nominee, and registered in the name of such Depository or
        nominee.

       

      “Holder” means a person in whose name a Security is registered or the holder of a Bearer
        Security.

       

      “Indenture” means this Indenture as amended or supplemented from time to time and shall
        include the form and terms of particular Series of Securities established as contemplated hereunder.

       

      “interest” with respect to any Discount Security which by its terms bears interest only
        after Maturity means interest payable after Maturity.

       

      “Maturity,” when used with respect to any Security or installment of principal thereof,
        means the date on which the principal of such Security or such installment of principal becomes due and payable as therein or herein provided, whether at the Stated Maturity or by declaration of acceleration, call for redemption or otherwise.

       

      “Officer” means the Chief Executive Officer, Chief Financial Officer, any Vice-President,
        the Treasurer, the Secretary, any Assistant Treasurer or any Assistant Secretary of the Company.

       

    

    
      2

      
        


    

    

       

      “Officers’ Certificate” means a certificate signed by two Officers, one of whom must be
        the Company’s principal executive officer, principal financial officer or principal accounting officer.

       

      “Opinion of Counsel” means a written opinion of legal counsel who is reasonably
        acceptable to the Trustee. The counsel may be an employee of or counsel to the Company.

       

      “Person” means any individual, corporation, partnership, joint venture, association,
        limited liability company, joint-stock company, trust, unincorporated organization or government or any agency or political subdivision thereof.

       

      “Principal” of a Security means the principal of the Security plus, when appropriate, the
        premium, if any, on, and any Additional Amounts in respect of, the Security.

       

      “Responsible Officer” means any officer of the Trustee in its Corporate Trust Office with
        direct responsibility for the administration of this Indenture and also means, with respect to a particular corporate trust matter, any other officer to whom any corporate trust matter is referred because of his or her knowledge of and familiarity
        with a particular subject.

       

      “SEC” means the Securities and Exchange Commission.

       

      “Securities” means the debentures, notes or other debt instruments of the Company of any
        Series authenticated and delivered under this Indenture.

       

      “Series” or “Series of Securities” means each
        series of debentures, notes or other debt instruments of the Company created pursuant to Sections 2.01 and 2.02 hereof.

       

      “Stated Maturity” means when used with respect to any Security or any installment of
        principal thereof or interest thereon, the date specified in such Security as the fixed date on which the principal of such Security or such installment of principal or interest is due and payable.

       

      “Subsidiary” means, with respect to any person, any corporation, association or other
        business entity of which more than 50% of the total voting power of shares of Capital Interests entitled (without regard to the occurrence of any contingency) to vote in the election of directors, managers or trustees thereof or, in the case of a
        partnership, more than 50% of the partners’ Capital Interests (considering all partners’ Capital Interests as a single class), is at the time owned or controlled, directly or indirectly, by such person or one or more of the other Subsidiaries of
        such person or combination thereof.

       

      “TIA” means the Trust Indenture Act of 1939 (15 U.S. Code Sections 77aaa-77bbbb) as in
        effect on the date of this Indenture and the rules and regulations promulgated thereunder; provided, however, that in the event the Trust Indenture Act of 1939 is amended after such date, “TIA” means, to the extent required by any such amendment,
        the Trust Indenture Act as so amended.

       

      “Trustee” means the person named as the “Trustee” in the first paragraph of this
        instrument until a successor Trustee shall have become such pursuant to the applicable provisions of this Indenture, and thereafter “Trustee” shall mean each person who is then a Trustee hereunder, and if at any time there is more than one such
        person, “Trustee” as used with respect to the Securities of any Series shall mean the Trustee with respect to Securities of that Series.

       

      “U.S. Government Obligations” means securities which are (i) direct obligations of The
        United States of America for the payment of which its full faith and credit is pledged or (ii) obligations of a person controlled or supervised by and acting as an agency or instrumentality of The United States of America the payment of which is
        unconditionally guaranteed as a full faith and credit obligation by The United States of America, and which are not callable or redeemable at the option of the issuer thereof, and shall also include a depository receipt issued by a bank or trust
        company as custodian with respect to any such U.S. Government Obligation or a specific payment of interest on or principal of any such U.S. Government Obligation held by such custodian for the account of the holder of a depository receipt, provided
        that (except as required by law) such custodian is not authorized to make any deduction from the amount payable to the holder of such depository receipt from any amount received by the custodian in respect of the U.S. Government Obligation
        evidenced by such depository receipt.

       

    

    
      3

      
        


    

    

       

      Section 1.02 Other Definitions.

       

      

      	
              TERM

            	 	
              DEFINED IN

              SECTION

            
	
              “Bankruptcy Law”

            	 	
              6.01

            
	
              “Custodian”

            	 	
              6.01

            
	
              “Event of Default”

            	 	
              6.01

            
	
              “Judgment Currency”

            	 	
              10.16

            
	
              “Legal Holiday”

            	 	
              10.07

            
	
              “mandatory sinking fund payment”

            	 	
              11.01

            
	
              “Market Exchange Rate”

            	 	
              10.15

            
	
              “New York Banking Day”

            	 	
              10.16

            
	
              “optional sinking fund payment”

            	 	
              11.01

            
	
              “Paying Agent”

            	 	
              2.04

            
	
              “Registrar”

            	 	
              2.04

            
	
              “Required Currency”

            	 	
              10.16

            
	
              “Service Agent”

            	 	
              2.04

            
	
              “successor person”

            	 	
              5.01

            


       

      Section 1.03 Incorporation by Reference of Trust Indenture Act.

       

      Whenever this Indenture refers to a provision of the TIA, the provision is incorporated by reference in and made a part of this
        Indenture. The following TIA terms used in this Indenture have the following meanings:

       

      “Commission” means the SEC.

       

      “indenture securities” means the Securities.

       

      “indenture security holder” means a Holder.

       

      “indenture to be qualified” means this Indenture.

       

      “indenture trustee” or “institutional trustee”
        means the Trustee.

       

      “obligor” on the indenture securities means the Company and any successor obligor upon
        the Securities.

       

      All other terms used in this Indenture that are defined by the TIA, defined by TIA reference to another statute or defined by SEC
        rule under the TIA and not otherwise defined herein are used herein as so defined.

       

      Section 1.04 Rules of Construction.

       

      Unless the context otherwise requires:

       

      (a) a term has the meaning assigned to it;

       

      (b) an accounting term not otherwise defined has the meaning assigned to it in accordance with generally accepted accounting
        principles;

       

      (c) references to “generally accepted accounting principles” and “GAAP” shall mean generally accepted accounting principles in
        effect as of the time when and for the period as to which such accounting principles are to be applied;

       

      (d) “or” is not exclusive;

       

      (e) words in the singular include the plural, and in the plural include the singular; and

       

      (f) provisions apply to successive events and transactions.

       

    

    
      4

      
        


    

    

       

      
      ARTICLE II

       

      THE SECURITIES

       

      Section 2.01 Issuable in Series. The aggregate principal amount of Securities that may be
        authenticated and delivered under this Indenture is unlimited. The Securities may be issued in one or more Series. All Securities of a Series shall be identical except as may be set forth or determined in the manner provided in a Board Resolution,
        supplemental indenture or Officers’ Certificate detailing the adoption of the terms thereof pursuant to authority granted under a Board Resolution. In the case of Securities of a Series to be issued from time to time, the Board Resolution,
        Officers’ Certificate or supplemental indenture detailing the adoption of the terms thereof pursuant to authority granted under a Board Resolution may provide for the method by which specified terms (such as interest rate, maturity date, record
        date or date from which interest shall accrue) are to be determined. Securities may differ between Series in respect of any matters, provided that all Series of Securities shall be equally and ratably entitled to the benefits of the Indenture.

       

      Section 2.02 Establishment of Terms of Series of Securities. At or prior to the issuance
        of any Securities within a Series, the following shall be established (as to the Series generally, in the case of Subsection 2.02(a) and either as to such Securities within the Series or as to the Series generally in the case of Subsections 2.02(b)
        through 2.02(s) by or pursuant to a Board Resolution, and set forth or determined in the manner provided in a Board Resolution, supplemental indenture or an Officers’ Certificate:

       

      (a) the form and title of the Series (which shall distinguish the Securities of that particular Series from the Securities of any
        other Series);

       

      (b) the price or prices (expressed as a percentage of the principal amount thereof) at which the Securities of the Series will be
        issued;

       

      (c) any limit upon the aggregate principal amount of the Securities of the Series which may be authenticated and delivered under
        this Indenture (except for Securities authenticated and delivered upon registration of transfer of, or in exchange for, or in lieu of, other Securities of the Series pursuant to Section 2.07, 2.08, 2.11, 3.06 or 9.06);

       

      (d) the date or dates on which the principal of the Securities of the Series is payable;

       

      (e) the rate or rates (which may be fixed or variable) per annum or, if applicable, the method used to determine such rate or
        rates (including, but not limited to, any commodity, commodity index, stock exchange index or financial index) at which the Securities of the Series shall bear interest, if any, the date or dates from which such interest, if any, shall accrue, the
        date or dates on which such interest, if any, shall commence and be payable and any regular record date for the interest payable on any interest payment date;

       

      (f) the place or places where the principal of and interest, if any, on the Securities of the Series shall be payable, where the
        Securities of such Series may be surrendered for registration of transfer or exchange and where notices and demands to or upon the Company in respect of the Securities of such Series and this Indenture may be served, and the method of such payment,
        if by wire transfer, mail or other means;

       

      (g) if applicable, the period or periods within which, the price or prices at which and the terms and conditions upon which the
        Securities of the Series may be redeemed, in whole or in part, at the option of the Company;

       

      (h) the obligation, if any, of the Company to redeem or purchase the Securities of the Series pursuant to any sinking fund or
        analogous provisions or at the option of a Holder thereof and the period or periods within which, the price or prices at which and the terms and conditions upon which Securities of the Series shall be redeemed or purchased, in whole or in part,
        pursuant to such obligation;

       

      (i) the dates, if any, on which and the price or prices at which the Securities of the Series will be repurchased by the Company
        at the option of the Holders thereof and other detailed terms and provisions of such repurchase obligations;

       

      (j) if other than denominations of $1,000 and any integral multiple thereof, the denominations in which the Securities of the
        Series shall be issuable;

       

      (k) if other than the principal amount thereof, the portion of the principal amount of the Securities of the Series that shall be
        payable upon declaration of acceleration of the maturity thereof pursuant to Section 6.02;

       

      (l) the currency of denomination of the Securities of the Series, which may be Dollars or any Foreign Currency, and the agency or
        organization, if any, responsible for overseeing such composite currency;

       

      (m) the provisions, if any, relating to any security provided for the Securities of the Series;

       

      
        5

        
          


      

       

      (n) any addition to or change in the Events of Default which applies to any Securities of the Series and any change in the right
        of the Trustee or the requisite Holders of such Securities to declare the principal amount thereof due and payable pursuant to Section 6.02;

       

      (o) any addition to or change in the covenants set forth in Articles IV or V which applies to Securities of the Series;

       

      (p) the provisions, if any, relating to conversion of any Securities of such Series, including, if applicable, the securities into
        which the Securities are convertible, the conversion price, the conversion period, provisions as to whether conversion will be mandatory, at the option of the Holders or at the option of the Company, the events requiring an adjustment of the
        conversion price and provisions affecting conversion if such Series of Securities are redeemed;

       

      (q) whether the Securities of such Series will be senior debt securities or subordinated debt securities and, if applicable, a
        description of the subordination terms thereof;

       

      (r) any depositaries, interest rate calculation agents, exchange rate calculation agents or other agents with respect to
        Securities of such Series if other than those appointed herein; and

       

      (s) any other terms of the Securities of the Series (which may modify or delete any provision of this Indenture insofar as it
        applies to such Series).

       

      All Securities of any one Series need not be issued at the same time and may be issued from time to time, consistent with the
        terms of this Indenture, if so provided by or pursuant to the Board Resolution, supplemental indenture hereto or Officers’ Certificate referred to above, and, unless otherwise provided in such Board Resolution, a Series may be reopened, without the
        consent of the Holders, for increases in the aggregate principal amount of such Series and issuances of additional Securities of such Series.

       

      Section 2.03 Execution and Authentication. Two Officers shall sign the Securities for the
        Company by manual or facsimile signature. If an Officer whose signature is on a Security no longer holds that office at the time the Security is authenticated, the Security shall nevertheless be valid. A Security shall not be valid until
        authenticated by the manual signature of the Trustee or an authenticating agent. The signature shall be conclusive evidence that the Security has been authenticated under this Indenture. The Trustee shall at any time, and from time to time,
        authenticate Securities for original issue in the principal amount provided in the Board Resolution, supplemental indenture hereto or Officers’ Certificate, upon receipt by the Trustee of a Company Order. Such Company Order may authorize
        authentication and delivery pursuant to oral or electronic instructions from the Company or its duly authorized agent or agents, which oral instructions shall be promptly confirmed in writing. Each Security shall be dated the date of its
        authentication unless otherwise provided by a Board Resolution, a supplemental indenture hereto or an Officers’ Certificate. The aggregate principal amount of Securities of any Series outstanding at any time may not exceed any limit upon the
        maximum principal amount for such Series set forth in the Board Resolution, supplemental indenture hereto or Officers’ Certificate delivered pursuant to Section 2.02, except as provided in Section 2.02 or 2.08. Prior to the issuance of Securities
        of any Series, the Trustee shall have received and (subject to Section 7.02) shall be fully protected in relying on: (a) the Board Resolution, supplemental indenture hereto or Officers’ Certificate establishing the form of the Securities of that
        Series or of Securities within that Series and the terms of the Securities of that Series or of Securities within that Series, (b) an Officers’ Certificate complying with Section 10.04 and (c) an Opinion of Counsel complying with Section 10.04. The
        Trustee shall have the right to decline to authenticate and deliver any Securities of such Series: (a) if the Trustee, being advised by counsel, determines that such action may not be taken lawfully; or (b) if the Trustee’s by its board of
        directors or trustees, executive committee or a trust committee of directors and/or vice-presidents shall determine in good faith that such action would expose the Trustee to personal liability to Holders of any then outstanding Series of
        Securities. The Trustee may appoint an authenticating agent acceptable to the Company to authenticate Securities. An authenticating agent may authenticate Securities whenever the Trustee may do so. Each reference in this Indenture to authentication
        by the Trustee includes authentication by such agent. An authenticating agent has the same rights as an Agent to deal with the Company or an Affiliate of the Company.

       

    

    
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      Section 2.04 Registrar and Paying Agent. The Company shall maintain, with respect to each
        Series of Securities, at the place or places specified with respect to such Series pursuant to Section 2.02, an office or agency where Securities of such Series may be presented or surrendered for payment (“Paying Agent”), where Securities of such
        Series may be surrendered for registration of transfer or exchange (“Registrar”) and where notices and demands to or upon the Company in respect of the Securities of such Series and this Indenture may be served (“Service Agent”). The Registrar
        shall keep a register with respect to each Series of Securities and to their transfer and exchange. The Company will give prompt written notice to the Trustee of the name and address, and any change in the name or address, of each Registrar, Paying
        Agent or Service Agent. If at any time the Company shall fail to maintain any such required Registrar, Paying Agent or Service Agent or shall fail to furnish the Trustee with the name and address thereof, such presentations, surrenders, notices and
        demands may be made or served at the Corporate Trust Office of the Trustee, and the Company hereby appoints the Trustee as its agent to receive all such presentations, surrenders, notices and demands. The Company may also from time to time
        designate one or more co-registrars, additional paying agents or additional service agents and may from time to time rescind such designations; provided, however, that no such designation or rescission shall in any manner relieve the Company of its
        obligations to maintain a Registrar, Paying Agent and Service Agent in each place so specified pursuant to Section 2.02 for Securities of any Series for such purposes. The Company will give prompt written notice to the Trustee of any such
        designation or rescission and of any change in the name or address of any such co-registrar, additional paying agent or additional service agent. The term “Registrar” includes any co-registrar; the term “Paying Agent” includes any additional paying
        agent; and the term “Service Agent” includes any additional service agent. The Company hereby appoints the Trustee the initial Registrar, Paying Agent and Service Agent for each Series unless another Registrar, Paying Agent or Service Agent, as the
        case may be, is appointed prior to the time Securities of that Series are first issued.

       

      Section 2.05 Paying Agent to Hold Money in Trust. The Company shall require each Paying
        Agent other than the Trustee to agree in writing that the Paying Agent will hold in trust, for the benefit of Holders of any Series of Securities, or the Trustee, all money held by the Paying Agent for the payment of principal of or interest on the
        Series of Securities, and will notify the Trustee of any default by the Company in making any such payment. While any such default continues, the Trustee may require a Paying Agent to pay all money held by it to the Trustee. The Company at any time
        may require a Paying Agent to pay all money held by it to the Trustee. Upon payment over to the Trustee, the Paying Agent (if other than the Company or a Subsidiary of the Company) shall have no further liability for the money. If the Company or a
        Subsidiary of the Company acts as Paying Agent, it shall segregate and hold in a separate trust fund for the benefit of Holders of any Series of Securities all money held by it as Paying Agent.

       

      Section 2.06 Holder Lists. The Trustee shall preserve in as current a form as is
        reasonably practicable the most recent list available to it of the names and addresses of Holders of each Series of Securities and shall otherwise comply with TIA Section 312(a). If the Trustee is not the Registrar, the Company shall furnish to the
        Trustee at least ten (10) days before each interest payment date and at such other times as the Trustee may request in writing a list, in such form and as of such date as the Trustee may reasonably require, of the names and addresses of Holders of
        each Series of Securities.

       

      Section 2.07 Transfer and Exchange. Where Securities of a Series are presented to the
        Registrar or a co-registrar with a request to register a transfer or to exchange them for an equal principal amount of Securities of the same Series, the Registrar shall register the transfer or make the exchange if its requirements for such
        transactions are met. To permit registrations of transfers and exchanges, the Trustee shall authenticate Securities at the Registrar’s request. No service charge shall be made for any registration of transfer or exchange (except as otherwise
        expressly permitted herein), but the Company may require payment of a sum sufficient to cover any transfer tax or similar governmental charge payable in connection therewith (other than any such transfer tax or similar governmental charge payable
        upon exchanges pursuant to Sections 2.11, 3.06 or 9.06). Neither the Company nor the Registrar shall be required (a) to issue, register the transfer of, or exchange Securities of any Series for the period beginning at the opening of business
        fifteen days immediately preceding the mailing of a notice of redemption of Securities of that Series selected for redemption and ending at the close of business on the day of such mailing, or (b) to register the transfer of or exchange Securities
        of any Series selected, called or being called for redemption as a whole or the portion being redeemed of any such Securities selected, called or being called for redemption in part.

       

      Section 2.08 Mutilated, Destroyed, Lost and Stolen Securities.

       

      (a) If any mutilated Security is surrendered to the Trustee, the Company shall execute and the Trustee shall authenticate and make
        available for delivery in exchange therefor a new Security of the same Series and of like tenor and principal amount and bearing a number not contemporaneously outstanding. If there shall be delivered to the Company and the Trustee (i) evidence to
        their satisfaction of the destruction, loss or theft of any Security and (ii) such security or indemnity as may be required by them to save each of them and any agent of either of them harmless, then, in the absence of notice to the Company or the
        Trustee that such Security has been acquired by a protected purchaser, the Company shall execute and upon its request the Trustee shall authenticate and make available for delivery, in lieu of any such destroyed, lost or stolen Security, a new
        Security of the same Series and of like tenor and principal amount and bearing a number not contemporaneously outstanding. In case any such mutilated, destroyed, lost or stolen Security has become or is about to become due and payable, the Company
        in its discretion may, instead of issuing a new Security, pay such Security.

       

    

    
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      (b) Upon the issuance of any new Security under this Section, the Company may require the payment of a sum sufficient to cover any
        tax or other governmental charge that may be imposed in relation thereto and any other expenses (including the fees and expenses of the Trustee) connected therewith. Every new Security of any Series issued pursuant to this Section in lieu of any
        destroyed, lost or stolen Security shall constitute an original additional contractual obligation of the Company, whether or not the destroyed, lost or stolen Security shall be at any time enforceable by anyone, and shall be entitled to all the
        benefits of this Indenture equally and proportionately with any and all other Securities of that Series duly issued hereunder. The provisions of this Section are exclusive and shall preclude (to the extent lawful) all other rights and remedies with
        respect to the replacement or payment of mutilated, destroyed, lost or stolen Securities.

       

      Section 2.09 Outstanding Securities. The Securities outstanding at any time are all the
        Securities authenticated by the Trustee except for those canceled by it, those delivered to it for cancellation, those reductions in the interest on a Global Security effected by the Trustee in accordance with the provisions hereof and those
        described in this Section as not outstanding. If a Security is replaced pursuant to Section 2.08, it ceases to be outstanding until the Trustee receives proof satisfactory to it that the replaced Security is held by a protected purchaser. If the
        Paying Agent (other than the Company, a Subsidiary of the Company or an Affiliate of the Company) holds on the Maturity of Securities of a Series money sufficient to pay such Securities payable on that date, then on and after that date such
        Securities of the Series cease to be outstanding and interest on them ceases to accrue. A Security does not cease to be outstanding because the Company or an Affiliate of the Company holds the Security. In determining whether the Holders of the
        requisite principal amount of outstanding Securities have given any request, demand, authorization, direction, notice, consent or waiver hereunder, the principal amount of a Discount Security that shall be deemed to be outstanding for such purposes
        shall be the amount of the principal thereof that would be due and payable as of the date of such determination upon a declaration of acceleration of the Maturity thereof pursuant to Section 6.02.

       

      Section 2.10 Treasury Securities. In determining whether the Holders of the required
        principal amount of Securities of a Series have concurred in any request, demand, authorization, direction, notice, consent or waiver, Securities of a Series owned by the Company shall be disregarded, except that for the purposes of determining
        whether the Trustee shall be protected in relying on any such request, demand, authorization, direction, notice, consent or waiver, only Securities of a Series that the Trustee knows are so owned shall be so disregarded.

       

      Section 2.11 Temporary Securities. Until definitive Securities are ready for delivery, the
        Company may prepare and the Trustee shall authenticate temporary Securities upon a Company Order. Temporary Securities shall be substantially in the form of definitive Securities but may have variations that the Company considers appropriate for
        temporary Securities. Without unreasonable delay, the Company shall prepare and the Trustee upon request shall authenticate definitive Securities of the same Series and date of maturity in exchange for temporary Securities. Until so exchanged,
        temporary securities shall have the same rights under this Indenture as the definitive Securities.

       

      Section 2.12 Cancellation. The Company at any time may deliver Securities to the Trustee
        for cancellation. The Registrar and the Paying Agent shall forward to the Trustee any Securities surrendered to them for registration of transfer, exchange or payment. The Trustee shall cancel all Securities surrendered for registration of
        transfer, exchange, payment, replacement or cancellation in accordance with its customary procedures and deliver such canceled Securities to the Company, unless the Company otherwise directs; provided that the Trustee shall not be required to
        destroy Securities. The Company may not issue new Securities to replace Securities that it has paid or delivered to the Trustee for cancellation.

       

      Section 2.13 Defaulted Interest. If the Company defaults in a payment of interest on a
        Series of Securities, it shall pay the defaulted interest, plus, to the extent permitted by law, any interest payable on the defaulted interest, to the persons who are Holders of the Series on a subsequent special record date. The Company shall fix
        the record date and payment date. At least ten (10) days before the record date, the Company shall mail to the Trustee and to each Holder of the Series a notice that states the record date, the payment date and the amount of interest to be paid.
        The Company may pay defaulted interest in any other lawful manner.

       

      
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      Section 2.14 Global Securities.

       

      (a) Terms of Securities. A Board Resolution, a supplemental indenture hereto or an Officers’ Certificate shall establish whether
        the Securities of a Series shall be issued in whole or in part in the form of one or more Global Securities and the Depository for such Global Security or Securities.

       

      (b) Transfer and Exchange. Notwithstanding any provisions to the contrary contained in Section 2.07 of the Indenture and in
        addition thereto, any Global Security shall be exchangeable pursuant to Section 2.07 of the Indenture for Securities registered in the names of Holders other than the Depository for such Security or its nominee only if (i) such Depository notifies
        the Company that it is unwilling or unable to continue as Depository for such Global Security or if at any time such Depository ceases to be a clearing agency registered under the Exchange Act, and, in either case, the Company fails to appoint a
        successor Depository registered as a clearing agency under the Exchange Act within 90 days of such event, (ii) the Company executes and delivers to the Trustee an Officers’ Certificate to the effect that such Global Security shall be so
        exchangeable or (iii) an Event of Default with respect to the Securities represented by such Global Security shall have happened and be continuing. Any Global Security that is exchangeable pursuant to the preceding sentence shall be exchangeable
        for Securities registered in such names as the Depository shall direct in writing in an aggregate principal amount equal to the principal amount of the Global Security with like tenor and terms.

       

      (c) Except as provided in Section 2.14(b), a Global Security may not be transferred except as a whole by the Depository with
        respect to such Global Security to a nominee of such Depository, by a nominee of such Depository to such Depository or another nominee of such Depository or by the Depository or any such nominee to a successor Depository or a nominee of such a
        successor Depository.

       

      (d) Legend. Any Global Security issued hereunder shall bear a legend in substantially the following form:

       

      “This Security is a Global Security within the meaning of the Indenture hereinafter referred to and is registered in the name of
        the Depository or a nominee of the Depository. This Security is exchangeable for Securities registered in the name of a person other than the Depository or its nominee only in the limited circumstances described in the Indenture, and may not be
        transferred except as a whole by the Depository to a nominee of the Depository, by a nominee of the Depository to the Depository or another nominee of the Depository or by the Depository or any such nominee to a successor Depository or a nominee of
        such a successor Depository.”

       

      (e) Acts of Holders. The Depository, as a Holder, may appoint agents and otherwise authorize participants to give or take any
        request, demand, authorization, direction, notice, consent, waiver or other action which a Holder is entitled to give or take under the Indenture.

       

      (f) Payments. Notwithstanding the other provisions of this Indenture, unless otherwise specified as contemplated by Section 2.02,
        payment of the principal of and interest, if any, on any Global Security shall be made to the Holder thereof.

       

      (g) Consents, Declaration and Directions. Except as provided in Section 2.14(h), the Company, the Trustee and any Agent shall
        treat a person as the Holder of such principal amount of outstanding Securities of such Series represented by a Global Security as shall be specified in a written statement of the Depository with respect to such Global Security, for purposes of
        obtaining any consents, declarations, waivers or directions required to be given by the Holders pursuant to this Indenture.

       

      (h) The Depository or its nominee, as registered owner of a Global Security, shall be the Holder of such Global Security for all
        purposes under the Indenture and the Securities, and owners of beneficial interests in a Global Security shall hold such interests pursuant to the Applicable Procedures. Accordingly, any such owner’s beneficial interest in a Global Security will be
        shown only on, and the transfer of such interest shall be effected only through, records maintained by the Depositary or its nominee and such owners of beneficial interests in a Global Security will not be considered the owners or holders thereof.

       

      Section 2.15 CUSIP Numbers. The Company in issuing the Securities may use “CUSIP” numbers
        (if then generally in use), and, if so, the Trustee shall use “CUSIP” numbers in notices of redemption as a convenience to Holders; provided that any such notice may state that no representation is made as to the correctness of such numbers either
        as printed on the Securities or as contained in any notice of a redemption and that reliance may be placed only on the other elements of identification printed on the Securities, and any such redemption shall not be affected by any defect in or
        omission of such numbers. The Company shall promptly notify the Trustee of any change in “CUSIP” numbers of which the Company becomes aware.

       

    

    
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      ARTICLE III

       

      REDEMPTION

       

      Section 3.01 Notice to Trustee. The Company may, with respect to any Series of Securities,
        reserve the right to redeem and pay the Series of Securities or may covenant to redeem and pay the Series of Securities or any part thereof prior to the Stated Maturity thereof at such time and on such terms as provided for in such Securities. If a
        Series of Securities is redeemable and the Company wants or is obligated to redeem prior to the Stated Maturity thereof all or part of the Series of Securities pursuant to the terms of such Securities, it shall notify the Trustee of the redemption
        date and the principal amount of Series of Securities to be redeemed.

       

      Section 3.02 Selection of Securities to be Redeemed. Unless otherwise indicated for a
        particular Series by a Board Resolution, a supplemental indenture or an Officers’ Certificate, if less than all the Securities of a Series are to be redeemed, the Trustee shall select the Securities of the Series to be redeemed in any manner that
        the Trustee deems fair and appropriate. The Trustee shall make the selection from Securities of the Series outstanding not previously called for redemption. The Trustee may select for redemption portions of the principal of Securities of the Series
        that have denominations larger than $1,000. Securities of the Series and portions of them it selects shall be in amounts of $1,000 or whole multiples of $1,000 or, with respect to Securities of any Series issuable in other denominations pursuant to
        Section 2.02(j), the minimum principal denomination for each Series and integral multiples thereof. Provisions of this Indenture that apply to Securities of a Series called for redemption also apply to portions of Securities of that Series called
        for redemption.

       

      Section 3.03 Notice of Redemption.

       

      (a) Unless otherwise indicated for a particular Series by Board Resolution, a supplemental indenture hereto or an Officers’
        Certificate, at least 30 days but not more than 60 days before a redemption date, the Company shall mail a notice of redemption by first-class mail to each Holder whose Securities are to be redeemed and, if any Bearer Securities are outstanding,
        publish on one occasion a notice in an Authorized Newspaper. The notice shall identify the Securities of the Series to be redeemed and shall state:

       

      (i) the redemption date;

       

      (ii) the redemption price;

       

      (iii) the name and address of the Paying Agent;

       

      (iv) that Securities of the Series called for redemption must be surrendered to the Paying Agent to collect
        the redemption price;

       

      (v) that interest on Securities of the Series called for redemption ceases to accrue on and after the
        redemption date;

       

      (vi) the CUSIP number, if any; and

       

      (vii) any other information as may be required by the terms of the particular Series or the Securities of a
        Series being redeemed.

       

      At the Company’s request, the Trustee shall give the notice of redemption in the Company’s name and at its expense.

       

      Section 3.04 Effect of Notice of Redemption. Once notice of redemption is mailed or
        published as provided in Section 3.03, Securities of a Series called for redemption become due and payable on the redemption date and at the redemption price. A notice of redemption may not be conditional. Upon surrender to the Paying Agent, such
        Securities shall be paid at the redemption price plus accrued interest to the redemption date; provided that installments of interest whose Stated Maturity is on or prior to the redemption date shall be payable to the Holders of such Securities (or
        one or more predecessor Securities) registered at the close of business on the relevant record date therefor according to their terms and the terms of this Indenture.

       

      
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      Section 3.05 Deposit of Redemption Price. On or before 10:00 a.m., New York City time, on
        the redemption date, the Company shall deposit with the Paying Agent money sufficient to pay the redemption price of and accrued interest, if any, on all Securities to be redeemed on that date.

       

      Section 3.06 Securities Redeemed in Part. Upon surrender of a Security that is redeemed in
        part, the Trustee shall authenticate for the Holder a new Security of the same Series and the same maturity equal in principal amount to the unredeemed portion of the Security surrendered.

       

      ARTICLE IV

       

      COVENANTS

       

      Section 4.01 Payment of Principal and Interest. The Company covenants and agrees for the
        benefit of the Holders of each Series of Securities that it will duly and punctually pay the principal of and interest, if any, on the Securities of that Series in accordance with the terms of such Securities and this Indenture.

       

      Section 4.02 SEC Reports. The Company shall, so long as any of the Securities are
        outstanding, electronically file with the Commission the annual, quarterly and other periodic reports that the Company is required to file (or would be otherwise required to file) with the Commission pursuant to Sections 13 and 15(d) of the
        Exchange Act. The Company also shall comply with the other provisions of TIA Section 314(a). Delivery of any reports, information and documents to the Trustee is for informational purposes only and the Trustee’s receipt of such shall not constitute
        constructive notice of any information contained therein or determinable from information contained therein, including the Company’s compliance with any of its covenants hereunder (as to which the Trustee is entitled to rely exclusively on an
        Officers’ Certificate).

       

      Section 4.03 Compliance Certificate. The Company shall, so long as any of the Securities
        are outstanding, deliver to the Trustee, within 120 days after the end of each fiscal year of the Company, an Officers’ Certificate stating whether or not to the knowledge of the signers thereof the Company is in default in the performance and
        observance of any of the terms, provisions and conditions hereof (without regard to any period of grace or requirement of notice provided hereunder), and if a Default or Event of Default shall have occurred, specifying all such Defaults or Events
        of Default and the nature and status thereof of which they may have knowledge. The Company shall, so long as any of the Securities are outstanding, deliver to the Trustee, within thirty (30) days after becoming aware of any Default or Event of
        Default, an Officers’ Certificate specifying such Default or Event of Default and what action the Company is taking or proposes to take with respect thereto.

       

      Section 4.04 Stay, Extension and Usury Laws. The Company covenants (to the extent that it
        may lawfully do so) that it will not at any time insist upon, plead or in any manner whatsoever claim or take the benefit or advantage of, any stay, extension or usury law wherever enacted, now or at any time hereafter in force, which may affect
        the covenants or the performance of this Indenture or the Securities and the Company (to the extent it may lawfully do so) hereby expressly waives all benefit or advantage of any such law and covenants that it will not, by resort to any such law,
        hinder, delay or impede the execution of any power herein granted to the Trustee, but will suffer and permit the execution of every such power as though no such law has been enacted.

       

      
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      ARTICLE V

       

      SUCCESSORS

       

      Section 5.01 When Company May Merge, Etc. The Company shall not consolidate with or merge
        with or into, or convey, transfer or lease all or substantially all of its properties and assets to, any person (a “successor person”) unless:

       

      (a) the Company is the surviving corporation or the successor person (if other than the Company) is organized and validly existing
        under the laws of Israel or any U.S. domestic jurisdiction and expressly assumes the Company’s obligations on the Securities and under this Indenture; and

       

      (b) immediately after giving effect to the transaction, no Default or Event of Default shall have occurred and be continuing.

       

      The Company shall deliver to the Trustee prior to the consummation of the proposed transaction an Officers’ Certificate to the
        foregoing effect and an Opinion of Counsel stating that the proposed transaction and any supplemental indenture comply with this Indenture.

       

      Section 5.02 Successor Corporation Substituted. Upon any consolidation or merger, or any
        sale, lease, conveyance or other disposition of all or substantially all of the assets of the Company in accordance with Section 5.01, the successor corporation formed by such consolidation or into or with which the Company is merged or to which
        such sale, lease, conveyance or other disposition is made shall succeed to, and be substituted for, and may exercise every right and power of, the Company under this Indenture with the same effect as if such successor person has been named as the
        Company herein; provided, however, that the predecessor Company in the case of a sale, conveyance or other disposition (other than a lease) shall be released from all obligations and covenants under this Indenture and the Securities.

       

      
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      ARTICLE VI

       

      DEFAULTS AND REMEDIES

       

      Section 6.01 Events of Default.

       

      “Event of Default,” wherever used herein with respect to Securities of any Series, means
        any one of the following events, unless in the establishing Board Resolution, supplemental indenture or Officers’ Certificate, it is provided that such Series shall not have the benefit of said Event of Default:

       

      (a) default in the payment of any interest on any Security of that Series when it becomes due and payable, and continuance of such
        default for a period of 30 days (unless the entire amount of such payment is deposited by the Company with the Trustee or with a Paying Agent prior to the expiration of such period of 30 days); or

       

      (b) default in the payment of principal of any Security of that Series at its Maturity; or

       

      (c) default in the performance or breach of any covenant or warranty of the Company in this Indenture (other than a covenant or
        warranty for which the consequences of nonperformance or breach are addressed elsewhere in this Section 6.01 and other than a covenant or warranty that has been included in this Indenture solely for the benefit of Series of Securities other than
        that Series), which default continues uncured for a period of 90 days after there has been given, by registered or certified mail, to the Company by the Trustee or to the Company and the Trustee by the Holders of not less than a majority in
        principal amount of the outstanding Securities of that Series a written notice specifying such default or breach and requiring it to be remedied and stating that such notice is a “Notice of Default” hereunder; or

       

      (d) the Company pursuant to or within the meaning of any Bankruptcy Law:

       

      (i) commences a voluntary case or proceeding;

       

      (ii) consents to the entry of an order for relief against it in an involuntary case,

       

      (iii) consents to the appointment of a Custodian of it or for all or substantially all of its property,

       

      (iv) makes a general assignment for the benefit of its creditors, or

       

      (v) makes an admission by writing that it is generally unable to pay its debts as the same become due; or

       

      (e) a court of competent jurisdiction enters an order or decree under any Bankruptcy Law that:

       

      (i) is for relief against the Company in an involuntary case,

       

      (ii) appoints a Custodian of the Company or for all or substantially all of its property, or

       

      (iii) orders the liquidation of the Company, and the order or decree remains unstayed and in effect for 90
        days; or

       

      (f) any other Event of Default provided with respect to Securities of that Series, which is specified in a Board Resolution, a
        supplemental indenture hereto or an Officers’ Certificate, in accordance with Section 2.02(n).

       

      
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      The term “Bankruptcy Law” means Title 11 of the U.S. Code or any similar federal or state
        law for the relief of debtors. The term “Custodian” means any receiver, trustee, assignee, liquidator or similar official under any Bankruptcy Law.

       

      Section 6.02 Acceleration of Maturity; Rescission and Annulment. If an Event of Default
        with respect to Securities of any Series at the time outstanding occurs and is continuing (other than an Event of Default referred to in Section 6.01(d) or (e)), then in every such case the Trustee or the Holders of not less than a majority in
        principal amount of the outstanding Securities of that Series may declare the principal amount (or, if any Securities of that Series are Discount Securities, such portion of the principal amount as may be specified in the terms of such Securities)
        of and accrued and unpaid interest, if any, on all of the Securities of that Series to be due and payable immediately, by a notice in writing to the Company (and to the Trustee if given by Holders), and upon any such declaration such principal
        amount (or specified amount) and accrued and unpaid interest, if any, shall become immediately due and payable. If an Event of Default specified in Section 6.01(d) or (e) shall occur, the principal amount (or specified amount) of and accrued and
        unpaid interest, if any, on all outstanding Securities shall ipso facto become and be immediately due and payable without any declaration or other act on the part of the Trustee or any Holder. At any time after such a declaration of acceleration
        with respect to any Series has been made and before a judgment or decree for payment of the money due has been obtained by the Trustee as hereinafter in this Article provided, the Holders of a majority in principal amount of the outstanding
        Securities of that Series, by written notice to the Company and the Trustee, may rescind and annul such declaration and its consequences if all Events of Default with respect to Securities of that Series, other than the non-payment of the principal
        and interest, if any, of Securities of that Series which have become due solely by such declaration of acceleration, have been cured or waived as provided in Section 6.13. No such rescission shall affect any subsequent Default or impair any right
        consequent thereon.

       

      Section 6.03 Collection of Indebtedness and Suits for Enforcement by Trustee.

       

      The Company covenants that if:

       

      (a) default is made in the payment of any interest on any Security when such interest becomes due and payable and such default
        continues for a period of 30 days, or

       

      (b) default is made in the payment of principal of any Security at the Maturity thereof,

       

      then the Company will, upon demand of the Trustee, pay to it, for the benefit of the Holders of such Securities, the whole amount
        then due and payable on such Securities for principal and interest and, to the extent that payment of such interest shall be legally enforceable, interest on any overdue principal and any overdue interest at the rate or rates prescribed therefor in
        such Securities and, in addition thereto, such further amount as shall be sufficient to cover the costs and expenses of collection, including the reasonable compensation, expenses, disbursements and advances of the Trustee, its agents and counsel.

       

      If the Company fails to pay such amounts forthwith upon such demand, the Trustee, in its own name and as trustee of an express
        trust, may institute a judicial proceeding for the collection of the sums so due and unpaid, may prosecute such proceeding to judgment or final decree and may enforce the same against the Company or any other obligor upon such Securities and
        collect the moneys adjudged or deemed to be payable in the manner provided by law out of the property of the Company or any other obligor upon such Securities, wherever situated.

       

      If an Event of Default with respect to any Securities of any Series occurs and is continuing, the Trustee may in its discretion
        proceed to protect and enforce its rights and the rights of the Holders of Securities of such Series by such appropriate judicial proceedings as the Trustee shall deem most effectual to protect and enforce any such rights, whether for the specific
        enforcement of any covenant or agreement in this Indenture or in aid of the exercise of any power granted herein, or to enforce any other proper remedy.

       

      Section 6.04 Trustee May File Proofs of Claim. In case of the pendency of any
        receivership, insolvency, liquidation, bankruptcy, reorganization, arrangement, adjustment, composition or other judicial proceeding relative to the Company or any other obligor upon the Securities or the property of the Company or of such other
        obligor or their creditors, the Trustee (irrespective of whether the principal of the Securities shall then be due and payable as therein expressed or by declaration or otherwise and irrespective of whether the Trustee shall have made any demand on
        the Company for the payment of overdue principal or interest) shall be entitled and empowered, by intervention in such proceeding or otherwise, (a) to file and prove a claim for the whole amount of principal and interest owing and unpaid in respect
        of the Securities and to file such other papers or documents as may be necessary or advisable in order to have the claims of the Trustee (including any claim for the reasonable compensation, expenses, disbursements and advances of the Trustee, its
        agents and counsel) and of the Holders allowed in such judicial proceeding, and (b) to collect and receive any moneys or other property payable or deliverable on any such claims and to distribute the same, and any custodian, receiver, assignee,
        trustee, liquidator, sequestrator or other similar official in any such judicial proceeding is hereby authorized by each Holder to make such payments to the Trustee and, in the event that the Trustee shall consent to the making of such payments
        directly to the Holders, to pay to the Trustee any amount due it for the reasonable compensation, expenses, disbursements and advances of the Trustee, its agents and counsel, and any other amounts due the Trustee under Section 7.07. Nothing herein
        contained shall be deemed to authorize the Trustee to authorize or consent to or accept or adopt on behalf of any Holder any plan of reorganization, arrangement, adjustment or composition affecting the Securities or the rights of any Holder thereof
        or to authorize the Trustee to vote in respect of the claim of any Holder in any such proceeding.

       

      
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      Section 6.05 Trustee May Enforce Claims Without Possession of Securities. All rights of
        action and claims under this Indenture or the Securities may be prosecuted and enforced by the Trustee without the possession of any of the Securities or the production thereof in any proceeding relating thereto, and any such proceeding instituted
        by the Trustee shall be brought in its own name as trustee of an express trust, and any recovery of judgment shall, after provision for the payment of the reasonable compensation, expenses, disbursements and advances of the Trustee, its agents and
        counsel, be for the ratable benefit of the Holders of the Securities in respect of which such judgment has been recovered.

       

      Section 6.06 Application of Money Collected.

       

      Any money collected by the Trustee pursuant to this Article shall be applied in the following order, at the date or dates fixed by
        the Trustee and, in case of the distribution of such money on account of principal or interest, upon presentation of the Securities and the notation thereon of the payment if only partially paid and upon surrender thereof if fully paid:

       

      First: To the payment of all amounts due the Trustee under Section 7.07; and

       

      Second: To the payment of the amounts then due and unpaid for principal of and interest on the Securities in respect of which or
        for the benefit of which such money has been collected, ratably, without preference or priority of any kind, according to the amounts due and payable on such Securities for principal and interest, respectively; and

       

      Third: To the Company.

       

      Section 6.07 Limitation on Suits. No Holder of any Security of any Series shall have any
        right to institute any proceeding, judicial or otherwise, with respect to this Indenture, or for the appointment of a receiver or trustee, or for any other remedy hereunder, unless:

       

      (a) such Holder has previously given written notice to the Trustee of a continuing Event of Default with respect to the Securities
        of that Series;

       

      (b) the Holders of at least a majority in principal amount of the outstanding Securities of that Series shall have made written
        request to the Trustee to institute proceedings in respect of such Event of Default in its own name as Trustee hereunder;

       

      (c) such Holder or Holders have offered to the Trustee reasonable indemnity against the costs, expenses and liabilities to be
        incurred in compliance with such request;

       

      (d) the Trustee for 60 days after its receipt of such notice, request and offer of indemnity has failed to institute any such
        proceeding; and

       

      (e) no direction inconsistent with such written request has been given to the Trustee during such 60-day period by the Holders of
        a majority in principal amount of the outstanding Securities of that Series;

       

      it being understood and intended that no one or more of such Holders shall have any right in any manner whatever by virtue of, or by availing of, any
        provision of this Indenture to affect, disturb or prejudice the rights of any other of such Holders, or to obtain or to seek to obtain priority or preference over any other of such Holders or to enforce any right under this Indenture, except in the
        manner herein provided and for the equal and ratable benefit of all such Holders.

       

    

    
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      Section 6.08 Unconditional Right of Holders to Receive Principal and Interest.
        Notwithstanding any other provision in this Indenture, the Holder of any Security shall have the right, which is absolute and unconditional, to receive payment of the principal of and interest, if any, on such Security on the Stated Maturity or
        Stated Maturities expressed in such Security (or, in the case of redemption, on the redemption date) and to institute suit for the enforcement of any such payment, and such rights shall not be impaired without the consent of such Holder.

       

      Section 6.09 Restoration of Rights and Remedies. If the Trustee or any Holder has
        instituted any proceeding to enforce any right or remedy under this Indenture and such proceeding has been discontinued or abandoned for any reason, or has been determined adversely to the Trustee or to such Holder, then and in every such case,
        subject to any determination in such proceeding, the Company, the Trustee and the Holders shall be restored severally and respectively to their former positions hereunder and thereafter all rights and remedies of the Trustee and the Holders shall
        continue as though no such proceeding had been instituted.

       

      Section 6.10 Rights and Remedies Cumulative. Except as otherwise provided with respect to
        the replacement or payment of mutilated, destroyed, lost or stolen Securities in Section 2.08, no right or remedy herein conferred upon or reserved to the Trustee or to the Holders is intended to be exclusive of any other right or remedy, and every
        right and remedy shall, to the extent permitted by law, be cumulative and in addition to every other right and remedy given hereunder or now or hereafter existing at law or in equity or otherwise. The assertion or employment of any right or remedy
        hereunder, or otherwise, shall not, to the extent permitted by law, prevent the concurrent assertion or employment of any other appropriate right or remedy.

       

      Section 6.11 Delay or Omission Not Waiver. No delay or omission of the Trustee or of any
        Holder of any Securities to exercise any right or remedy accruing upon any Event of Default shall impair any such right or remedy or constitute a waiver of any such Event of Default or an acquiescence therein. Every right and remedy given by this
        Article or by law to the Trustee or to the Holders may be exercised from time to time, and as often as may be deemed expedient, by the Trustee or by the Holders, as the case may be.

       

      Section 6.12 Control by Holders. The Holders of a majority in principal amount of the
        outstanding Securities of any Series shall have the right to direct the time, method and place of conducting any proceeding for any remedy available to the Trustee, or exercising any trust or power conferred on the Trustee, with respect to the
        Securities of such Series, provided that:

       

      (a) such direction shall not be in conflict with any rule of law or with this Indenture,

       

      (b) the Trustee may take any other action deemed proper by the Trustee which is not inconsistent with such direction, and

       

      (c) subject to the provisions of Section 6.01, the Trustee shall have the right to decline to follow any such direction if the
        Trustee in good faith shall, by a Responsible Officer of the Trustee, determine that the proceeding so directed would involve the Trustee in personal liability.

       

      Section 6.13 Waiver of Past Defaults. The Holders of not less than a majority in principal
        amount of the outstanding Securities of any Series may on behalf of the Holders of all the Securities of such Series waive any past Default hereunder with respect to such Series and its consequences, except a Default (i) in the payment of the
        principal of or interest on any Security of such Series (provided, however, that the Holders of a majority in principal amount of the outstanding Securities of any Series may rescind an acceleration and its consequences, including any related
        payment default that resulted from such acceleration) or (ii) in respect of a covenant or provision hereof which cannot be modified or amended without the consent of the Holder of each outstanding Security of such Series affected. Upon any such
        waiver, such Default shall cease to exist, and any Event of Default arising therefrom shall be deemed to have been cured, for every purpose of this Indenture; but no such waiver shall extend to any subsequent or other Default or impair any right
        consequent thereon.

       

      Section 6.14 Undertaking for Costs. All parties to this Indenture agree, and each Holder
        of any Security by his acceptance thereof shall be deemed to have agreed, that any court may in its discretion require, in any suit for the enforcement of any right or remedy under this Indenture, or in any suit against the Trustee for any action
        taken, suffered or omitted by it as Trustee, the filing by any party litigant in such suit of an undertaking to pay the costs of such suit, and that such court may in its discretion assess reasonable costs, including reasonable attorneys’ fees,
        against any party litigant in such suit, having due regard to the merits and good faith of the claims or defenses made by such party litigant; but the provisions of this Section shall not apply to any suit instituted by the Company, to any suit
        instituted by the Trustee, to any suit instituted by any Holder, or group of Holders, holding in the aggregate more than 10% in principal amount of the outstanding Securities of any Series, or to any suit instituted by any Holder for the
        enforcement of the payment of the principal of or interest on any Security on or after the Stated Maturity or Stated Maturities expressed in such Security (or, in the case of redemption, on the redemption date).

       

      

       

      
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      ARTICLE VII

       

      TRUSTEE

       

      Section 7.01 Duties of Trustee.

       

      (a) If an Event of Default has occurred and is continuing, the Trustee shall exercise the rights and powers vested in it by this
        Indenture and use the same degree of care and skill in their exercise as a prudent person would exercise or use under the circumstances in the conduct of such person’s own affairs.

       

      (b) Except during the continuance of an Event of Default:

       

      (i) The Trustee need perform only those duties that are specifically set forth in this Indenture and no
        others.

       

      (ii) In the absence of bad faith on its part, the Trustee may conclusively rely, as to the truth of the
        statements and the correctness of the opinions expressed therein, upon Officers’ Certificates or Opinions of Counsel furnished to the Trustee and conforming to the requirements of this Indenture; however, in the case of any such Officers’
        Certificates or Opinions of Counsel which by any provisions hereof are specifically required to be furnished to the Trustee, the Trustee shall examine such Officers’ Certificates and Opinions of Counsel to determine whether or not they conform to
        the requirements of this Indenture.

       

      (c) The Trustee may not be relieved from liability for its own negligent action, its own negligent failure to act or its own
        willful misconduct, except that:

       

      (i) This paragraph does not limit the effect of paragraph (b) of this Section.

       

      (ii) The Trustee shall not be liable for any error of judgment made in good faith by a Responsible Officer,
        unless it is proved that the Trustee was negligent in ascertaining the pertinent facts.

       

      (iii) The Trustee shall not be liable with respect to any action taken, suffered or omitted to be taken by it
        with respect to Securities of any Series in good faith in accordance with the direction of the Holders of a majority in principal amount of the outstanding Securities of such Series relating to the time, method and place of conducting any
        proceeding for any remedy available to the Trustee, or exercising any trust or power conferred upon the Trustee, under this Indenture with respect to the Securities of such Series.

       

      (d) Every provision of this Indenture that in any way relates to the Trustee is subject to paragraph (a), (b) and (c) of this
        Section.

       

      (e) The Trustee may refuse to perform any duty or exercise any right or power at the request or direction of any Holder unless it
        receives indemnity satisfactory to it against any loss, liability or expense.

       

      (f) The Trustee shall not be liable for interest on any money received by it except as the Trustee may agree in writing with the
        Company. Money held in trust by the Trustee need not be segregated from other funds except to the extent required by law.

       

      (g) No provision of this Indenture shall require the Trustee to risk its own funds or otherwise incur any financial liability in
        the performance of any of its duties, or in the exercise of any of its rights or powers, if it shall have reasonable grounds for believing that repayment of such funds or adequate indemnity against such risk is not reasonably assured to it.

       

      (h) The Paying Agent, the Registrar and any Service Agent or authenticating agent shall be entitled to the protections, immunities
        and standard of care as are set forth in paragraphs (a), (b) and (c) of this Section with respect to the Trustee.

       

    

    
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      Section 7.02 Rights of Trustee.

       

      (a) The Trustee may rely on and shall be protected in acting or refraining from acting upon any document believed by it to be
        genuine and to have been signed or presented by the proper person. The Trustee need not investigate any fact or matter stated in the document.

       

      (b) Before the Trustee acts or refrains from acting, it may require an Officers’ Certificate. The Trustee shall not be liable for
        any action it takes or omits to take in good faith in reliance on such Officers’ Certificate.

       

      (c) The Trustee may act through agents and shall not be responsible for the misconduct or negligence of any agent appointed with
        due care. No Depository shall be deemed an agent of the Trustee, and the Trustee shall not be responsible for any act or omission by any Depository.

       

      (d) The Trustee shall not be liable for any action it takes or omits to take in good faith which it believes to be authorized or
        within its rights or powers, provided that the Trustee’s conduct does not constitute negligence or bad faith.

       

      (e) The Trustee may consult with counsel, and the advice of such counsel or any Opinion of Counsel shall be full and complete
        authorization and protection in respect of any action taken, suffered or omitted by it hereunder without negligence and in good faith and in reliance thereon.

       

      (f) The Trustee shall be under no obligation to exercise any of the rights or powers vested in it by this Indenture at the request
        or direction of any of the Holders of Securities unless such Holders shall have offered to the Trustee reasonable security or indemnity against the costs, expenses and liabilities which might be incurred by it in compliance with such request or
        direction.

       

      (g) The Trustee shall not be bound to make any investigation into the facts or matters stated in any resolution, certificate,
        statement, instrument, opinion, report, notice, request, direction, consent, order, bond, debenture, note, other evidence of indebtedness or other paper or document, but the Trustee, in its discretion, may make such further inquiry or investigation
        into such facts or matters as it may see fit.

       

      (h) The Trustee shall not be deemed to have notice of any Default or Event of Default unless a Responsible Officer of the Trustee
        has actual knowledge thereof or unless written notice of any event which is in fact such a default is received by the Trustee at the Corporate Trust Office of the Trustee, and such notice references the Securities generally or the Securities of a
        particular Series and this Indenture.

       

      (i) The permissive rights of the Trustee enumerated herein shall not be construed as duties.

       

      Section 7.03 Individual Rights of Trustee. The Trustee in its individual or any other
        capacity may become the owner or pledgee of Securities and may otherwise deal with the Company or an Affiliate of the Company with the same rights it would have if it were not Trustee. Any Agent may do the same with like rights. The Trustee is also
        subject to Sections 7.10 and 7.11.

       

      Section 7.04 Trustee’s Disclaimer. The Trustee makes no representation as to the validity
        or adequacy of this Indenture or the Securities, it shall not be accountable for the Company’s use of the proceeds from the Securities, and it shall not be responsible for any statement in the Securities other than its authentication.

       

      Section 7.05 Notice of Defaults. If a Default or Event of Default occurs and is continuing
        with respect to the Securities of any Series and if it is known to a Responsible Officer of the Trustee, the Trustee shall mail to each Holder of the Securities of that Series and, if any Bearer Securities are outstanding, publish on one occasion
        in an Authorized Newspaper, notice of a Default or Event of Default within 90 days after it occurs or, if later, after a Responsible Officer of the Trustee has knowledge of such Default or Event of Default. Except in the case of a Default or Event
        of Default in payment of principal of or interest on any Security of any Series, the Trustee may withhold the notice if and so long as its corporate trust committee or a committee of its Responsible Officers in good faith determines that
        withholding the notice is in the interests of Holders of that Series.

       

    

    
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      Section 7.06 Reports by Trustee to Holders. Within 60 days after May 15 in each year, the
        Trustee shall transmit by mail to all Holders, as their names and addresses appear on the register kept by the Registrar and, if any Bearer Securities are outstanding, publish in an Authorized Newspaper, a brief report dated as of such May 15, in
        accordance with, and to the extent required under, TIA Section 313(a), (b), (c) and (d). A copy of each report at the time of its mailing to Holders of any Series shall be filed with the SEC and each stock exchange on which the Securities of that
        Series are listed. The Company shall promptly notify the Trustee when Securities of any Series are listed on any stock exchange.

       

      Section 7.07 Compensation and Indemnity. The Company shall pay to the Trustee from time to
        time compensation for its services as the Company and the Trustee shall from time to time agree upon in writing. The Trustee’s compensation shall not be limited by any law on compensation of a trustee of an express trust. The Company shall
        reimburse the Trustee upon request for all reasonable out-of-pocket expenses incurred by it. Such expenses shall include the reasonable compensation and expenses of the Trustee’s agents and counsel. The Company shall indemnify each of the Trustee
        and any predecessor Trustee (including the cost of defending itself) against any loss, liability or expense, including taxes (other than taxes based upon, measured by or determined by the income of the Trustee) incurred by it except as set forth in
        this Section 7.07 in the performance of its duties under this Indenture as Trustee or Agent. The Trustee shall notify the Company promptly of any claim for which it may seek indemnity. The Company shall defend the claim and the Trustee shall
        cooperate in the defense. The Trustee may have one separate counsel and the Company shall pay the reasonable fees and expenses of such counsel. The Company need not pay for any settlement made without its consent, which consent shall not be
        unreasonably withheld. This indemnification shall apply to officers, directors, employees, shareholders and agents of the Trustee. The Company need not reimburse any expense or indemnify against any loss or liability incurred by the Trustee or by
        any officer, director, employee, shareholder or agent of the Trustee through the negligence or bad faith of any such persons. To secure the Company’s payment obligations in this Section, the Trustee shall have a lien prior to the Securities of any
        Series on all money or property held or collected by the Trustee, except that held in trust to pay principal of and interest on particular Securities of that Series. When the Trustee incurs expenses or renders services after an Event of Default
        specified in Section 6.01(d) or (e) occurs, the expenses and the compensation for the services are intended to constitute expenses of administration under any Bankruptcy Law. The provisions of this Section shall survive the resignation or removal
        of the Trustee and the termination of this Indenture.

       

      Section 7.08 Replacement of Trustee. A resignation or removal of the Trustee and
        appointment of a successor Trustee shall become effective only upon the successor Trustee’s acceptance of appointment as provided in this Section. The Trustee may resign with respect to the Securities of one or more Series by so notifying the
        Company at least 30 days prior to the date of the proposed resignation. The Holders of a majority in principal amount of the Securities of any Series may remove the Trustee with respect to that Series by so notifying the Trustee and the Company.
        The Company may remove the Trustee with respect to Securities of one or more Series if:

       

      (a) the Trustee fails to comply with Section 7.10;

       

      (b) the Trustee is adjudged bankrupt or insolvent or an order for relief is entered with respect to the Trustee under any
        Bankruptcy Law;

       

      (c) a Custodian or public officer takes charge of the Trustee or its property; or

       

      (d) the Trustee becomes incapable of acting.

       

      If the Trustee resigns or is removed or if a vacancy exists in the office of Trustee for any reason, the Company shall promptly
        appoint a successor Trustee.

       

      If a successor Trustee with respect to the Securities of any one or more Series does not take office within 60 days after the
        retiring Trustee resigns or is removed, the retiring Trustee, the Company or the Holders of at least a majority in principal amount of the Securities of the applicable Series may petition any court of competent jurisdiction for the appointment of a
        successor Trustee.

       

      A successor Trustee shall deliver a written acceptance of its appointment to the retiring Trustee and to the Company. Immediately
        after that, the retiring Trustee shall transfer all property held by it as Trustee to the successor Trustee subject to the lien provided for in Section 7.07, the resignation or removal of the retiring Trustee shall become effective, and the
        successor Trustee shall have all the rights, powers and duties of the Trustee with respect to each Series of Securities for which it is acting as Trustee under this Indenture. A successor Trustee shall mail a notice of its succession to each Holder
        of each such Series and, if any Bearer Securities are outstanding, publish such notice on one occasion in an Authorized Newspaper. Notwithstanding replacement of the Trustee pursuant to this Section 7.08, the Company’s obligations under Section
        7.07 hereof shall continue for the benefit of the retiring Trustee with respect to expenses and liabilities incurred by it prior to the date of such replacement.

       

      Section 7.09 Successor Trustee by Merger, etc. If the Trustee consolidates with, merges or
        converts into, or transfers all or substantially all of its corporate trust business to, another corporation, the successor corporation without any further act shall be the successor Trustee.

       

      Section 7.10 Eligibility; Disqualification. This Indenture shall always have a Trustee who
        satisfies the requirements of TIA Section 310(a)(1), (2) and (5). The Trustee shall comply with TIA Section 310(b).

       

      Section 7.11 Preferential Collection of Claims Against Company. The Trustee is subject to
        TIA Section 311(a), excluding any creditor relationship listed in TIA Section 311(b). A Trustee who has resigned or been removed shall be subject to TIA Section 311(a) to the extent indicated.

       

      
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      ARTICLE VIII

       

      SATISFACTION AND DISCHARGE; DEFEASANCE

       

      Section 8.01 Satisfaction and Discharge of Indenture.

       

      This Indenture shall upon Company Order cease to be of further effect (except as hereinafter provided in this Section 8.01), and
        the Trustee, at the expense of the Company, shall execute proper instruments acknowledging satisfaction and discharge of this Indenture, when

       

      (a) any of the following shall have occurred:

       

      (i) no Securities have been issued hereunder;

       

      (ii) all Securities theretofore authenticated and delivered (other than Securities that have been destroyed,
        lost or stolen and that have been replaced or paid) have been delivered to the Trustee for cancellation; or

       

      (iii) all such Securities not theretofore delivered to the Trustee for cancellation (1) have become due and
        payable, or (2) will become due and payable at their Stated Maturity within one year, or (3) are to be called for redemption within one year under arrangements satisfactory to the Trustee for the giving of notice of redemption by the Trustee in the
        name, and at the expense, of the Company;

       

      and the Company has irrevocably deposited or caused to be deposited with the Trustee as trust funds in trust an amount sufficient
        for the purpose of paying and discharging the entire indebtedness on such Securities not theretofore delivered to the Trustee for cancellation, for principal and interest to the date of such deposit (in the case of Securities which have become due
        and payable on or prior to the date of such deposit) or to the Stated Maturity or redemption date, as the case may be;

       

      (b) the Company has paid or caused to be paid all other sums payable hereunder by the Company; and

       

      (c) the Company has delivered to the Trustee an Officers’ Certificate and an Opinion of Counsel, each stating that all conditions
        precedent herein provided for relating to the satisfaction and discharge of this Indenture have been complied with.

       

      Notwithstanding the satisfaction and discharge of this Indenture, the obligations of the Company to the Trustee under Section 7.07
        and, if money shall have been deposited with the Trustee pursuant to clause (a) of this Section, the provisions of Sections 2.04 , 2.05 , 2.07, 2.08, 8.01, 8.02 and 8.05 shall survive.

       

      Section 8.02 Application of Trust Funds; Indemnification.

       

      (a) Subject to the provisions of Section 8.05, all money deposited with the Trustee pursuant to Section 8.01, all money and U.S.
        Government Obligations or Foreign Government Obligations deposited with the Trustee pursuant to Section 8.03 or 8.04 and all money received by the Trustee in respect of U.S. Government Obligations or Foreign Government Obligations deposited with
        the Trustee pursuant to Section 8.03 or 8.04, shall be held in trust and applied by it, in accordance with the provisions of the Securities and this Indenture, to the payment, either directly or through any Paying Agent (other than the Company
        acting as its own Paying Agent) as the Trustee may determine, to the persons entitled thereto, of the principal and interest for whose payment such money has been deposited with or received by the Trustee or analogous payments as contemplated by
        Sections 8.03 or 8.04.

       

      
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      (b) The Company shall pay and shall indemnify the Trustee against any tax, fee or other charge imposed on or assessed against U.S.
        Government Obligations or Foreign Government Obligations deposited pursuant to Sections 8.03 or 8.04 or the interest and principal received in respect of such obligations other than any payable by or on behalf of Holders.

       

      (c) The Trustee shall deliver or pay to the Company from time to time upon Company Request any U.S. Government Obligations or
        Foreign Government Obligations or money held by it as provided in Sections 8.03 or 8.04 which, in the opinion of a nationally recognized firm of independent certified public accountants expressed in a written certification thereof delivered to the
        Trustee, are then in excess of the amount thereof which then would have been required to be deposited for the purpose for which such U.S. Government Obligations or Foreign Government Obligations or money were deposited or received. This provision
        shall not authorize the sale by the Trustee of any U.S. Government Obligations or Foreign Government Obligations held under this Indenture.

       

      Section 8.03 Legal Defeasance of Securities of any Series. Unless this Section 8.03 is
        otherwise specified, pursuant to Section 2.02(s), to be inapplicable to Securities of any Series, the Company shall be deemed to have paid and discharged the entire indebtedness on all the outstanding Securities of any Series on the 91st day after
        the date of the deposit referred to in subparagraph (d) hereof, and the provisions of this Indenture, as it relates to such outstanding Securities of such Series, shall no longer be in effect (and the Trustee, at the expense of the Company, shall,
        at Company Request, execute proper instruments acknowledging the same), except as to:

       

      (a) the rights of Holders of Securities of such Series to receive, from the trust funds described in subparagraph (d) hereof, (i)
        payment of the principal of and each installment of principal of and interest on the outstanding Securities of such Series on the Stated Maturity of such principal or installment of principal or interest, and (ii) the benefit of any mandatory
        sinking fund payments applicable to the Securities of such Series on the day on which such payments are due and payable in accordance with the terms of this Indenture and the Securities of such Series; and

       

      (b) the provisions of Sections 2.04, 2.05, 2.07, 2.08, 8.02, 8.03 and 8.05; and

       

      (c) the rights, powers, trust and immunities of the Trustee hereunder;

       

      provided that, the following conditions shall have been satisfied:

       

      (d) with reference to this Section 8.03, the Company shall have deposited or caused to be irrevocably deposited (except as
        provided in Section 8.02(c)) with the Trustee as trust funds in trust for the purpose of making the following payments, specifically pledged as security for and dedicated solely to the benefit of the Holders of such Securities (i) in the case of
        Securities of such Series denominated in Dollars, cash in Dollars and/or U.S. Government Obligations, or (ii) in the case of Securities of such Series denominated in a Foreign Currency (other than a composite currency), money and/or Foreign
        Government Obligations, which through the payment of interest and principal in respect thereof in accordance with their terms, will provide (and without reinvestment and assuming no tax liability will be imposed on such Trustee), not later than one
        day before the due date of any payment of money, an amount in cash, sufficient, in the opinion of a nationally recognized firm of independent public accountants expressed in a written certification thereof delivered to the Trustee, to pay and
        discharge each installment of principal of and interest, if any, on and any mandatory sinking fund payments in respect of all the Securities of such Series on the dates such installments of interest or principal and such sinking fund payments are
        due;

       

      (e) such deposit will not result in a breach or violation of, or constitute a default under, this Indenture or any other agreement
        or instrument to which the Company is a party or by which it is bound;

       

      (f) no Default or Event of Default with respect to the Securities of such Series shall have occurred and be continuing on the date
        of such deposit or during the period ending on the 91st day after such date;

       

      (g) the Company shall have delivered to the Trustee an Officers’ Certificate and an Opinion of Counsel to the effect that (i) the
        Company has received from, or there has been published by, the Internal Revenue Service a ruling, or (ii) since the date of execution of this Indenture, there has been a change in the applicable Federal income tax law, in either case to the effect
        that, and based thereon such Opinion of Counsel shall confirm that, the Holders of the Securities of such Series will not recognize income, gain or loss for Federal income tax purposes as a result of such deposit, defeasance and discharge and will
        be subject to Federal income tax on the same amounts and in the same manner and at the same times as would have been the case if such deposit, defeasance and discharge had not occurred;

       

    

    
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      (h) the Company shall have delivered to the Trustee an Officers’ Certificate stating that the deposit was not made by the Company
        with the intent of preferring the Holders of the Securities of such Series over any other creditors of the Company or with the intent of defeating, hindering, delaying or defrauding any other creditors of the Company;

       

      (i) the Company shall have delivered to the Trustee an Officers’ Certificate and an Opinion of Counsel, each stating that all
        conditions precedent provided for relating to the defeasance contemplated by this Section have been complied with; and

       

      (j) such defeasance shall not result in the trust arising from such deposit constituting an investment company within the meaning
        of the Investment Company Act of 1940, as amended, unless such trust shall be registered under such Act or exempt from registration thereunder.

       

      Section 8.04 Covenant Defeasance. Unless this Section 8.04 is otherwise specified,
        pursuant to Section 2.02(s), to be inapplicable to Securities of any Series, on and after the 91st day after the date of the deposit referred to in subparagraph (a) hereof, the Company may omit to comply with respect to the Securities of any Series
        with any term, provision or condition set forth under Sections 4.02, 4.03, and 5.01 as well as any additional covenants specified in a supplemental indenture for such Series of Securities or a Board Resolution or an Officers’ Certificate delivered
        pursuant to Section 2.02 (and the failure to comply with any such covenants shall not constitute a Default or Event of Default with respect to such Series under Section 6.01) and the occurrence of any event specified in a supplemental indenture for
        such Series of Securities or a Board Resolution or an Officers’ Certificate delivered pursuant to Section 2.02 and designated as an Event of Default shall not constitute a Default or Event of Default hereunder, with respect to the Securities of
        such Series, provided that the following conditions shall have been satisfied:

       

      (a) with reference to this Section 8.04, the Company has deposited or caused to be irrevocably deposited (except as provided in
        Section 8.02(c)) with the Trustee as trust funds in trust for the purpose of making the following payments specifically pledged as security for, and dedicated solely to, the benefit of the Holders of such Securities (i) in the case of Securities of
        such Series denominated in Dollars, cash in Dollars and/or U.S. Government Obligations, or (ii) in the case of Securities of such Series denominated in a Foreign Currency (other than a composite currency), money and/or Foreign Government
        Obligations, which through the payment of interest and principal in respect thereof in accordance with their terms, will provide (and without reinvestment and assuming no tax liability will be imposed on such Trustee), not later than one day before
        the due date of any payment of money, an amount in cash, sufficient, in the opinion of a nationally recognized firm of independent certified public accountants expressed in a written certification thereof delivered to the Trustee, to pay and
        discharge each installment of principal of and interest, if any, on and any mandatory sinking fund payments in respect of the Securities of such Series on the dates such installments of interest or principal and such sinking fund payments are due;

       

      (b) such deposit will not result in a breach or violation of, or constitute a default under, this Indenture or any other agreement
        or instrument to which the Company is a party or by which it is bound;

       

      (c) no Default or Event of Default with respect to the Securities of such Series shall have occurred and be continuing on the date
        of such deposit or during the period ending on the 91st day after such date;

       

      (d) the Company shall have delivered to the Trustee an Opinion of Counsel to the effect that Holders of the Securities of such
        Series will not recognize income, gain or loss for federal income tax purposes as a result of such deposit and covenant defeasance and will be subject to federal income tax on the same amounts, in the same manner and at the same times as would have
        been the case if such deposit and covenant defeasance had not occurred;

       

      (e) the Company shall have delivered to the Trustee an Officers’ Certificate and an Opinion of Counsel, each stating that all
        conditions precedent herein provided for relating to the covenant defeasance contemplated by this Section have been complied with; and

       

      (f) Such defeasance shall not result in the trust arising from such deposit constituting an investment company within the meaning
        of the Investment Company Act of 1940, as amended, unless such trust shall be registered under such Act or exempt from registration thereunder.

       

      Section 8.05 Repayment to Company. The Trustee and the Paying Agent shall pay to the
        Company upon written request any money held by them for the payment of principal and interest that remains unclaimed for two years, and after such time, Holders entitled to the money must look to the Company for payment as general creditors unless
        an applicable abandoned property law designates another person.

       

      Section 8.06 Reinstatement. If the Trustee or the Paying Agent is unable to apply any
        money deposited with respect to Securities of any series in accordance with Section 8.01 by reason of any legal proceeding or by reason of any order or judgment of any court or governmental authority enjoining, restraining or otherwise prohibiting
        such application, the obligations of the Company under this Indenture with respect to the Securities of such series and under the Securities of such series shall be revived and reinstated as though no deposit had occurred pursuant to Section 8.01
        until such time as the Trustee or the Paying Agent is permitted to apply all such money in accordance with Section 8.01; provided, however, that if the Company has made any payment of principal of, premium (if any) or interest on any Additional
        Amounts with respect to any Securities because of the reinstatement of its obligations, the Company shall be subrogated to the rights of the Holders of such Securities to receive such payment from the money held by the Trustee or the Paying Agent.

       

       

      

      
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      ARTICLE IX

       

      AMENDMENTS AND WAIVERS

       

      Section 9.01 Without Consent of Holders. The Company and the Trustee may amend or
        supplement this Indenture or the Securities of one or more Series without the consent of any Holder:

       

      (a) to evidence the succession of another person to the Company under this Indenture and the Securities and the assumption by any
        such successor person of the obligations of the Company hereunder and under the Securities;

       

      (b) to add or remove covenants of the Company for the benefit of the Holders of all or any series of Securities (and if such
        covenants are to be for the benefit of less than all series of Securities, stating that such covenants are expressly being included for the benefit of such series) or to surrender any right or power herein conferred upon the Company provided such
        action does not adversely affect the interests of the Company;

       

      (c) to add any additional Events of Default;

       

      (d) to add to or change any of the provisions of this Indenture to such extent as shall be necessary to permit or facilitate the
        issuance of Securities in bearer form, registrable or not registrable as to principal, and with or without interest coupons, or to permit or facilitate the issuance of Securities in uncertificated form;

       

      (e) to add to, change or eliminate any of the provisions of this Indenture in respect of one or more series of Securities,
        provided that any such addition, change or elimination (A) shall neither (i) apply to any Security of any series created prior to the execution of such supplemental indenture and entitled to the benefit of such provision nor (ii) modify the rights
        of the Holder of any such Security with respect to such provision or (B) shall become effective only when there is no such Security Outstanding;

       

      (f) to establish the forms or terms of the Securities of any series issued pursuant to the terms hereof;

       

      (g) to cure any ambiguity or correct any inconsistency in this Indenture;

       

      (h) to evidence and provide for the acceptance of appointment hereunder by a successor Trustee with respect to the Securities of
        one or more series and to add to or change any of the provisions of this Indenture as shall be necessary to provide for or facilitate the administration of the trusts hereunder by more than one Trustee;

       

      (i) to qualify this Indenture under the Trust Indenture Act;

       

      (j) to provide for uncertificated securities in addition to certificated securities;

       

      (k) to supplement any provisions of this Indenture necessary to permit or facilitate the defeasance and discharge of any series of
        Securities, provided that such action does not adversely affect the interests of the Holders of Securities of such series or any other series; and

       

      (l) to comply with the rules or regulations of any securities exchange or automated quotation system on which any of the
        Securities may be listed or traded.

       

      
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      Section 9.02 With Consent of Holders. The Company and the Trustee may enter into a
        supplemental indenture with the written consent of the Holders of at least a majority in principal amount of the outstanding Securities of each Series affected by such supplemental indenture (including consents obtained in connection with a tender
        offer or exchange offer for the Securities of such Series), for the purpose of adding any provisions to or changing in any manner or eliminating any of the provisions of this Indenture or of any supplemental indenture or of modifying in any manner
        the rights of the Holders of each such Series. Except as provided in Section 6.13, the Holders of at least a majority in principal amount of the outstanding Securities of any Series by notice to the Trustee (including consents obtained in
        connection with a tender offer or exchange offer for the Securities of such Series) may waive compliance by the Company with any provision of this Indenture or the Securities with respect to such Series. It shall not be necessary for the consent of
        the Holders of Securities under this Section 9.02 to approve the particular form of any proposed supplemental indenture or waiver, but it shall be sufficient if such consent approves the substance thereof. After a supplemental indenture or waiver
        under this section becomes effective, the Company shall mail to the Holders of Securities affected thereby and, if any Bearer Securities affected thereby are outstanding, publish on one occasion in an Authorized Newspaper, a notice briefly
        describing the supplemental indenture or waiver. Any failure by the Company to mail or publish such notice, or any defect therein, shall not, however, in any way impair or affect the validity of any such supplemental indenture or waiver.

       

      Section 9.03 Limitations. Without the consent of each Holder affected, an amendment or
        waiver may not:

       

      (a) reduce the amount of Securities whose Holders must consent to an amendment, supplement or waiver;

       

      (b) reduce the rate of or extend the time for payment of interest (including default interest) on any Security;

       

      (c) reduce the principal or change the Stated Maturity of any Security or reduce the amount of, or postpone the date fixed for,
        the payment of any sinking fund or analogous obligation;

       

      (d) reduce the principal amount of Discount Securities payable upon acceleration of the maturity thereof;

       

      (e) waive a Default or Event of Default in the payment of the principal of or interest, if any, on any Security (except a
        rescission of acceleration of the Securities of any Series by the Holders of at least a majority in principal amount of the outstanding Securities of such Series and a waiver of the payment default that resulted from such acceleration);

       

      (f) make the principal of or interest, if any, on any Security payable in any currency other than that stated in the Security;

       

      (g) make any change in Sections 6.08, 6.13, or 9.03; or

       

      (h) waive a redemption payment with respect to any Security.

       

      Section 9.04 Compliance with Trust Indenture Act. Every amendment to this Indenture or the
        Securities of one or more Series shall be set forth in a supplemental indenture hereto that complies with the TIA as then in effect.

       

      Section 9.05 Revocation and Effect of Consents. Until an amendment is set forth in a
        supplemental indenture or a waiver becomes effective, a consent to it by a Holder of a Security is a continuing consent by the Holder and every subsequent Holder of a Security or portion of a Security that evidences the same debt as the consenting
        Holder’s Security, even if notation of the consent is not made on any Security. However, any such Holder or subsequent Holder may revoke the consent as to his Security or portion of a Security if the Trustee receives the notice of revocation before
        the date of the supplemental indenture or the date the waiver becomes effective. Any amendment or waiver once effective shall bind every Holder of each Series affected by such amendment or waiver unless it is of the type described in any of clauses
        (a) through (h) of Section 9.03. In that case, the amendment or waiver shall bind each Holder of a Security who has consented to it and every subsequent Holder of a Security or portion of a Security that evidences the same debt as the consenting
        Holder’s Security.

       

      Section 9.06 Notation on or Exchange of Securities. The Trustee may place an appropriate
        notation about an amendment or waiver on any Security of any Series thereafter authenticated. The Company in exchange for Securities of that Series may issue and the Trustee shall authenticate upon request new Securities of that Series that reflect
        the amendment or waiver.

       

      Section 9.07 Trustee Protected. In executing, or accepting the additional trusts created
        by, any supplemental indenture permitted by this Article or the modifications thereby of the trusts created by this Indenture, the Trustee shall be entitled to receive, in addition to the documents required by Section 10.04, and (subject to Section
        7.01) shall be fully protected in relying upon, an Opinion of Counsel stating that the execution of such supplemental indenture is authorized or permitted by this Indenture. The Trustee shall sign all supplemental indentures, except that the
        Trustee need not sign any supplemental indenture that adversely affects its rights.

       

      
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      ARTICLE X

       

      MISCELLANEOUS

       

      Section 10.01 Trust Indenture Act Controls. If any provision of this Indenture limits,
        qualifies or conflicts with another provision which is required or deemed be included in this Indenture by the TIA, such required or deemed provision shall control.

       

      Section 10.02 Notices.

       

      (a) Any notice or communication by the Company or the Trustee to the other, or by a Holder to the Company or the Trustee, is duly
        given if in writing and delivered in person or mailed by first-class mail or sent by telecopier transmission addressed as follows:

       

      if to the Company:

       

      MediWound Ltd.

       

      42 Hayarkon Street

       

      Yavne 8122745, Israel

       

      Telephone: +972 (77) 971-4100

       

      if to the Trustee:

       

      [●]

       

      (b) The Company or the Trustee by notice to the other may designate additional or different addresses for subsequent notices or
        communications. Any notice or communication to a Holder shall be mailed by first-class mail to his address shown on the register kept by the Registrar and, if any Bearer Securities are outstanding, published in an Authorized Newspaper. Failure to
        mail a notice or communication to a Holder of any Series or any defect in it shall not affect its sufficiency with respect to other Holders of that or any other Series. If a notice or communication is mailed or published in the manner provided
        above, within the time prescribed, it is duly given, whether or not the Holder receives it. If the Company mails a notice or communication to Holders, it shall mail a copy to the Trustee and each Agent at the same time.

       

      (c) Any notice or demand that by any provision of this Indenture is required or permitted to be given or served by the Company
        may, at the Company’s written request received by the Trustee not fewer than five (5) Business Days prior (or such shorter period of time as may be acceptable to the Trustee) to the date on which such notice must be given or served, be given or
        served by the Trustee in the name of and at the expense of the Company.

       

      Section 10.03 Communication by Holders with Other Holders. Holders of any Series may
        communicate pursuant to TIA Section 312(b) with other Holders of that Series or any other Series with respect to their rights under this Indenture or the Securities of that Series or all Series. The Company, the Trustee, the Registrar and anyone
        else shall have the protection of TIA Section 312(c).

       

      Section 10.04 Certificate and Opinion as to Conditions Precedent. Upon any request or
        application by the Company to the Trustee to take any action under this Indenture, the Company shall furnish to the Trustee:

       

      (a) an Officers’ Certificate stating that, in the opinion of the signers, all conditions precedent, if any, provided for in this
        Indenture relating to the proposed action have been complied with; and

       

      (b) an Opinion of Counsel stating that, in the opinion of such counsel, all such conditions precedent have been complied with.

       

      
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      Section 10.05 Statements Required in Certificate or Opinion. Each certificate or opinion
        with respect to compliance with a condition or covenant provided for in this Indenture (other than a certificate provided pursuant to TIA Section 314(a)(4)) shall comply with the provisions of TIA Section 314(e) and shall include:

       

      (a) a statement that the person making such certificate or opinion has read such covenant or condition;

       

      (b) a brief statement as to the nature and scope of the examination or investigation upon which the statements or opinions
        contained in such certificate or opinion are based;

       

      (c) a statement that, in the opinion of such person, he has made such examination or investigation as is necessary to enable him
        to express an informed opinion as to whether or not such covenant or condition has been complied with; and

       

      (d) a statement as to whether or not, in the opinion of such person, such condition or covenant has been complied with.

       

      Section 10.06 Rules by Trustee and Agents. The Trustee may make reasonable rules for
        action by or a meeting of Holders of one or more Series. Any Agent may make reasonable rules and set reasonable requirements for its functions.

       

      Section 10.07 Legal Holidays. Unless otherwise provided by Board Resolution, Officers’
        Certificate or supplemental indenture hereto for a particular Series, a “Legal Holiday” is any day that is not a Business Day. If a payment date is a Legal Holiday at a place of payment, payment may be made at that place on the next succeeding day
        that is not a Legal Holiday, and no interest shall accrue for the intervening period.

       

      Section 10.08 No Recourse Against Others. A director, officer, employee or stockholder, as
        such, of the Company shall not have any liability for any obligations of the Company under the Securities or the Indenture or for any claim based on, in respect of or by reason of such obligations or their creation. Each Holder by accepting a
        Security waives and releases all such liability. The waiver and release are part of the consideration for the issue of the Securities.

       

      Section 10.09 Counterparts. This Indenture may be executed in any number of counterparts
        and by the parties hereto in separate counterparts, each of which when so executed shall be deemed to be an original and all of which taken together shall constitute one and the same agreement.

       

      Section 10.10 Governing Laws. This Indenture and the Securities will be governed by, and
        construed in accordance with, the internal laws of the State of New York, without regard to conflict of law principles that would result in the application of any law other than the laws of the State of New York.

       

      Section 10.11 No Adverse Interpretation of Other Agreements. This Indenture may not be
        used to interpret another indenture, loan or debt agreement of the Company or a Subsidiary of the Company. Any such indenture, loan or debt agreement may not be used to interpret this Indenture.

       

      Section 10.12 Successors. All agreements of the Company in this Indenture and the
        Securities shall bind its successor. All agreements of the Trustee in this Indenture shall bind its successor.

       

      Section 10.13 Severability. In case any provision in this Indenture or in the Securities
        shall be invalid, illegal or unenforceable, the validity, legality and enforceability of the remaining provisions shall not in any way be affected or impaired thereby.

       

      Section 10.14 Table of Contents, Headings, Etc. The Table of Contents, Cross-Reference
        Table, and headings of the Articles and Sections of this Indenture have been inserted for convenience of reference only, are not to be considered a part hereof, and shall in no way modify or restrict any of the terms or provisions hereof.

       

      Section 10.15 Securities in a Foreign Currency. Unless otherwise specified in a Board
        Resolution, a supplemental indenture hereto or an Officers’ Certificate delivered pursuant to Section 2.02 of this Indenture with respect to a particular Series of Securities, whenever for purposes of this Indenture any action may be taken by the
        Holders of a specified percentage in aggregate principal amount of Securities of all Series or all Series affected by a particular action at the time outstanding and, at such time, there are outstanding Securities of any Series which are
        denominated in a coin or currency other than Dollars, then the principal amount of Securities of such Series which shall be deemed to be outstanding for the purpose of taking such action shall be that amount of Dollars that could be obtained for
        such amount at the Market Exchange Rate at such time. For purposes of this Section 10.15, “Market Exchange Rate” shall mean the noon Dollar buying rate in New York City for cable transfers of that currency as published by the Federal Reserve Bank
        of New York. If such Market Exchange Rate is not available for any reason with respect to such currency, the Trustee shall use, in its sole discretion and without liability on its part, such quotation of the Federal Reserve Bank of New York as of
        the most recent available date, or quotations from one or more major banks in The City of New York or in the country of issue of the currency in question or such other quotations as the Trustee, upon consultation with the Company, shall deem
        appropriate. The provisions of this paragraph shall apply in determining the equivalent principal amount in respect of Securities of a Series denominated in currency other than Dollars in connection with any action taken by Holders of Securities
        pursuant to the terms of this Indenture. All decisions and determinations of the Trustee regarding the Market Exchange Rate or any alternative determination provided for in the preceding paragraph shall be in its sole discretion and shall, in the
        absence of manifest error, to the extent permitted by law, be conclusive for all purposes and irrevocably binding upon the Company and all Holders.

       

      
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      Section 10.16 Judgment Currency. The Company agrees, to the fullest extent that it may
        effectively do so under applicable law, that (a) if for the purpose of obtaining judgment in any court it is necessary to convert the sum due in respect of the principal of or interest or other amount on the Securities of any Series (the “Required
        Currency”) into a currency in which a judgment will be rendered (the “Judgment Currency”), the rate of exchange used shall be the rate at which in accordance with normal banking procedures the Trustee could purchase in The City of New York the
        Required Currency with the Judgment Currency on the day on which final unappealable judgment is entered, unless such day is not a New York Banking Day, then the rate of exchange used shall be the rate at which in accordance with normal banking
        procedures the Trustee could purchase in The City of New York the Required Currency with the Judgment Currency on the New York Banking Day preceding the day on which final unappealable judgment is entered and (b) its obligations under this
        Indenture to make payments in the Required Currency (i) shall not be discharged or satisfied by any tender, any recovery pursuant to any judgment (whether or not entered in accordance with subsection (a)), in any currency other than the Required
        Currency, except to the extent that such tender or recovery shall result in the actual receipt, by the payee, of the full amount of the Required Currency expressed to be payable in respect of such payments, (ii) shall be enforceable as an
        alternative or additional cause of action for the purpose of recovering in the Required Currency the amount, if any, by which such actual receipt shall fall short of the full amount of the Required Currency so expressed to be payable, and (iii)
        shall not be affected by judgment being obtained for any other sum due under this Indenture. For purposes of the foregoing, “New York Banking Day” means any day except a Saturday, Sunday or a legal holiday in The City of New York on which banking
        institutions are authorized or required by law, regulation or executive order to close.

       

      ARTICLE XI

       

      SINKING FUNDS

       

      Section 11.01 Applicability of Article. The provisions of this Article shall be applicable
        to any sinking fund for the retirement of the Securities of a Series, except as otherwise permitted or required by any form of Security of such Series issued pursuant to this Indenture. The minimum amount of any sinking fund payment provided for by
        the terms of the Securities of any Series is herein referred to as a “ mandatory sinking fund payment ” and any other amount provided for by the terms of Securities of such Series is herein referred to as an
        “ optional sinking fund payment .” If provided for by the terms of Securities of any Series, the cash amount of any sinking fund payment may be subject to reduction as provided in Section 11.02. Each sinking
        fund payment shall be applied to the redemption of Securities of any Series as provided for by the terms of the Securities of such Series.

       

      Section 11.02 Satisfaction of Sinking Fund Payments with Securities. The Company may, in
        satisfaction of all or any part of any sinking fund payment with respect to the Securities of any Series to be made pursuant to the terms of such Securities (1) deliver outstanding Securities of such Series to which such sinking fund payment is
        applicable (other than any of such Securities previously called for mandatory sinking fund redemption) and (2) apply as credit Securities of such Series to which such sinking fund payment is applicable and which have been repurchased by the Company
        or redeemed either at the election of the Company pursuant to the terms of such Series of Securities (except pursuant to any mandatory sinking fund) or through the application of permitted optional sinking fund payments or other optional
        redemptions pursuant to the terms of such Securities, provided that such Securities have not been previously so credited. Such Securities shall be received by the Trustee, together with an Officers’ Certificate with respect thereto, not later than
        15 days prior to the date on which the Trustee begins the process of selecting Securities for redemption, and shall be credited for such purpose by the Trustee at the price specified in such Securities for redemption through operation of the
        sinking fund and the amount of such sinking fund payment shall be reduced accordingly. If as a result of the delivery or credit of Securities in lieu of cash payments pursuant to this Section 11.02, the principal amount of Securities of such Series
        to be redeemed in order to exhaust the aforesaid cash payment shall be less than $100,000, the Trustee need not call Securities of such Series for redemption, except upon receipt of a Company Order that such action be taken, and such cash payment
        shall be held by the Trustee or a Paying Agent and applied to the next succeeding sinking fund payment, provided, however, that the Trustee or such Paying Agent shall from time to time upon receipt of a Company Order pay over and deliver to the
        Company any cash payment so being held by the Trustee or such Paying Agent upon delivery by the Company to the Trustee of Securities of that Series purchased by the Company having an unpaid principal amount equal to the cash payment required to be
        released to the Company.

       

      
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      Section 11.03 Redemption of Securities for Sinking Fund. Not less than 45 days (unless
        otherwise indicated in the Board Resolution, supplemental indenture or Officers’ Certificate in respect of a particular Series of Securities) prior to each sinking fund payment date for any Series of Securities, the Company will deliver to the
        Trustee an Officers’ Certificate specifying the amount of the next ensuing mandatory sinking fund payment for that Series pursuant to the terms of that Series, the portion thereof, if any, which is to be satisfied by payment of cash and the portion
        thereof, if any, which is to be satisfied by delivering and crediting of Securities of that Series pursuant to Section 11.02, and the optional amount, if any, to be added in cash to the next ensuing mandatory sinking fund payment, and the Company
        shall thereupon be obligated to pay the amount therein specified. Not less than 30 days (unless otherwise indicated in the Board Resolution, Officers’ Certificate or supplemental indenture in respect of a particular Series of Securities) before
        each such sinking fund payment date the Trustee shall select the Securities to be redeemed upon such sinking fund payment date in the manner specified in Section 3.02 and cause notice of the redemption thereof to be given in the name of and at the
        expense of the Company in the manner provided in Section 3.03. Such notice having been duly given, the redemption of such Securities shall be made upon the terms and in the manner stated in Sections 3.04, 3.05 and 3.06.

       

      IN WITNESS WHEREOF, the parties hereto have caused this Indenture to be duly executed and attested, all as of the day and year
        first above written.

       

      

      	
              MEDIWOUND LTD.

            	 
	
              By:

            	 	 
	
              Name:

            	 
	
              Title:

            	 
	 	 
	 	 
	
              as Trustee

            	 
	
              By:

            	 	 
	
              Name:

            	 
	
              Title:

            	 


       

      

      

       

    

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