# 1 UNITED STATES ENVIRONMENTAL PROTECTION AGENCY WASHINGTON, DC 20460

OFFICE OF PREVENTION, PESTICIDES AND TOXIC SUBSTANCES



# PC Code: 128997 DP Barcodes: DP362764 Date : 11/ 1 2 /2009

MEMORANDUM

Subject: Evaluation of Potential Ecological Risks from the Proposed New Use of Tebuconazole on Fruiting Vegetables (Crop Group 8).

To: Mary Waller, Risk Manager Tracy Keigwin , Risk Manager Reviewer Registration Division (7505P)

From: Christopher Koper , Chemist Anita Ullagaddi, Environmental Protection Specialist Joseph Chisholm, Environmental Protection Specialist Nancy Andrews, Chief Brian Anderson, RAPL Environmental Risk Branch I Environmental Fate and Effects Division (7507P)

Attached is the Environmental Fate and Effects Divisio n’s (EFED’s) ecological risk assessment for the proposed Section 3 registration for the use of the fungicide tebuconazole on fruiting vegetables (crop group 8, Eggplant, groundcherry, pepino, pepper, tomatillo, tomato)

.

# 2 1. Executive Summary

This asses sment evaluates the proposed use of tebuconazole on fruiting vegetables. The following commodities are included in the fruiting vegetables crop group :

Eggplant; groundcherry ( Physalis spp); pepino; pepper (includes bell pepper, chili pepper, cooking peppe r, pimento, sweet pepper); tomatillo; tomato

Previous Section 3 assessments on new uses of tebuconazole have identified direct risks to mammals, fish, terrestrial and aquatic plants, and saltwater invertebrates (DP 3 33331, 2007). The current assessment evaluates proposed uses of tebuconazole with equivalent application rates and seasonal loads as previous assessments

. The p roposed maximum single application
rate is 0.225 lbs a.i./Acre ; six applications are allowed with seven days between applications fo r a maximum seasonal application rate of 1.35 lbs a.i./Acre. Potential risks to non

- target organisms identified in this assessment are summarized in Table 1 and are similar to those identified in previous assessments, although chronic RQs for birds also ex ceeded the chronic LOC.

This assessment identified direct risks to fish, saltwater invertebrates, birds, mammals, and terrestrial plants and identified indirect risks to organisms that may depend on them for sustenance. These conclusions are similar to conclusions presented in previous assessments.

Table 1. Summary of LOC Exceedances for the Proposed New Uses of Tebuconazole Use on Fruiting Vegetables

Effect Taxonomic Group

Birds Mammals Terrest. Plants Terrest. Inverts FW and SW Fish FW Invert SW Invert Aquatic Plants

Direct Effect LOC Exceedance 

# √ √ √

-- √

-- √

--

Indirect Effect Potential 

# √ √ √ √ √ √ √ √



# Data Gaps S ince the 2007 assessment was conducted, submission of an acute oral toxicity study o n a passerine species was included in the P art 158 data requirements. Therefore, a data gap exist s for the acute oral study in a passerine species. In addition, EFED has identified issues with the terrestrial plant toxicity studies. A submitted Tier I seedling emergence and vegetative vigor study ( MRID 458213

- 01) was classified as supplemental because the product was not tested at the maximum (single application) label use rate. The concentration tested was 0.404 lb a.i./acre, while Folicur 3.6F is registered for use on dry bulb vegetables to contro l white rot at a maximum single application rate of 0.564 lb a.i./acre (EPA Reg. No. 265

- 752, stamped June 17, 2009)

. While this current action proposes a single application rate of 0.225 lb a.i./acre and, therefore, the aforementioned study would satisfy data requirements, EFED recognizes a Tier I seedling emergence and vegetative vigor study using the rate of 0.564 lb a.i./acre as a data gap for certain

# 3 uses that have already been registered. Pending the results of a new Tier I study, it may be possible t o upgrade the submitted Tier II studies (MRID 458213

- 02, 472992

- 01) to an acceptable
status.

2. Scope of Assessment

Tebuconazole is a sterol demethylation inhibitor (DMI) fungicide. It is systemic and shows activity against rusts, white rot, powdery mi ldew, and Cercospora leaf spot. Tebuconazole provides protective activity by preventing completion of the infection process. It is rapidly absorbed by plants and is translocated systemically in the young growing tissues.

T h e previous risk assessment ( D P 3 33331

, 2007

- brassica leafy vegetables, garden beets, green onions, dry bulb vegetables ) evaluated applications that are similar to those proposed for fruiting vegetables. A n abbreviated review was conducted by EFED for the following reasons :

**•** Proposed application rates, intervals, and seasonal loads are within the range of previously approved application rates; and

**•** No new exposure methods have been approved for standard risk assessments since the previous risk assessme nt was performed in 2007

.

A new te rrestrial plant seedling emergence toxicity study (OPPTS 850.4225) has been submitted and was reviewed for this assessment (MRID 472992

- 01). Results of this study were incorporated into the risk assessment. No other new data were reviewed for this assess ment.

3. Exposure Assessment

3.1 Proposed Tebuconazole Application Information

Table 2 shows the proposed application rate for fruiting vegetables based on the submitted label dated December 15, 2008

. The p rop osed Folicur ® 

# 3.6F use is labeled for foliar spray applications using aerial and ground equipment

. The proposed application rate is 6 application s of 0.225 lb a.i./acre applied at 7

- day intervals

. T his rate is equ ivalent to the highest appl ication
rate for previously registered pome and stone fruit uses (DP316942, 2006)

.

Table 2

. Proposed Tebuconazole Use

Proposed Label Use Method 1 

# Application Rate 2 

# (Interval)
Folicur ® 

# 3.6F Fruiting Vegetables ( Crop Group 8) Eggplant Groundcherry Pepino Pepper Tomatillo Tomato A

– foliar 6 apps @ 0.225 lb a .i./acre (7

- day interval)

G

– foliar 6 apps @ 0.225 lb a.i./acre (7

- day interval)

1 

# A = aerial application. G = ground application. All applications are liquid unless otherwise specified.

# 4 Table 2

. Proposed Tebuconazole Use

Proposed Label Use Method 1 

# Application Rate 2 

# (Interval)

2 

# (3.6 lbs. a.i./gallon ) ( gallon/128 fl. oz.)(8 fl. oz./acre) = 0.225 lbs. a.i./acre



# 3.2 Aquatic Exposure Modeling for Tebuconazole

The aquatic exposure concentrations presented in this assessment were solely based on modeling estimates . N o surface and limited (less than detection limit) groundwater monitoring data are available for tebuconazole . To simulate surface water exposure for the ecological risk

assessmen t, the Tier II PRZM/EXAMS model was used.

3.2.1 PRZM

- EXAMS Model

T he Pesticide Root Zone Model (PRZM, Carsel et al ., 1997) and the Exposure Analysis Modeling System (EXAMS, Burns, 1997) with the standard pond scenario were used to generate aquatic estimated environmental concentrations (EECs) . PRZM (v3.12.2, May 12, 2005 ) simulates fate and transport on the agricultural field whereas EXAMS ( v 2.98.04 .06, April 25, 2005 ) simulates the fate and resulting daily concentrations in the water body. Simulations are carried out with t he linkage program shell, PE5.pl (PE5, PE Version 5.0, November 15, 2006 ), which incorporates pepper and tomato scenarios developed by EFED. Simulations are run for multiple (usually 30) years, and the EECs represent peak values that are expected once every ten years based on the 30 years of daily values generated during the simulation. Additional information on these models can be found at: http://www.epa.gov/oppefed1/models/water/index.htm

. The aquatic exposure is estimated for the maximum application pattern to a 10

- ha field bordering a 1

- ha pond, 2

- m deep (20,000 m 3 

# ) with no outlet. Exposure estimates generated using this standard pond are intended to represent a wide variety of vulnerable water bodies that occur at the top of watersheds including prairie pot holes, playa lakes, wetlands, v ernal pools, man

- made and natural ponds, and intermittent and first

- order streams. As a group, there are factors that make these water bodies more or less vulnerable than the standard surrogate pond. Static water bodies that have larger ratios of pestici de

- treated drainage area to water body volume would be expected to have higher peak EECs than the standard pond. These water bodies will be either smaller in size or have large drainage areas. Smaller water bodies have limited storage capacity and thus m ay overflow and carry pesticide in the discharge, whereas the standard pond has no discharge. As watershed size increases beyond 10

- ha, it becomes increasingly unlikely that the entire watershed is planted with a non

- major single crop that is all treated simultaneously with the pesticide. For major crops like cereal grains, however, this may not be the case. Headwater streams can also have peak concentrations higher than the standard pond, but they likely persist for only short periods of time and are th en carried and dissipated downstream.

OPP standard PRZM crop scenarios, which consist of location

- specific soils, weather, and cropping practices, were used in the simulations to represent proposed labeled uses of tebuconazole . These scenarios were devel oped to represent high

- end exposure sites in terms of

# 5 vulnerability to runoff and erosion and subsequent off

- site transport of pesticide. Tebuconazole is being proposed for fruiting vegetables (crop group 8). OPP standard PRZM scenarios for the proposed uses that were modeled include Florida pepper and Florida, Pennsylvania, and California tomato . A summary of the input parameters used to estimate tebuconazole concentrations in the aquatic systems for ecological risk assessment are listed in Table 3

.

Ta ble 3. PRZM/EXAMS Input P arameters for Tebuconazole

. Input Parameter Value Comment Source

Scenario : Fruiting Vegetables (Crop Group 8): Pepper: FL Pepper Tomato: CA Tomato PA Tomato FL Tomato All ava ilable scenarios for e ach use N/A 1



# Maximum Single Application Rate: lbs a

. i./A (kg a.i./ha) F ruiting Vegetables (all scenarios ): 0.225 (0.253) 2 

# Product label states 3.6 lbs a.i./gallon and application rate as 8 fl. oz. per acre Product label: Folicur ® 

# 3.6F EPA Reg. No. 264

- 752

Maximum Number of Applications (season): F ruiting Vegetables (all scenarios ) : 6 Label specifies rates per season. If crops are ro tated with those on which tebuconazole is used, yearly

rates on a given field may be higher. Product label: Folic ur ® 

# 3.6F EPA Reg. No. 264

- 752

Application Interval (d ays ) F ruiting Vegetables (all scenarios ) : 7 Intervals were selected to reflect labeled application patterns. Product label: Folicur ® 

# 3.6F EPA Reg. No. 264

- 752 Application Method: Foliar : aerial ground Foliar application may be made using aerial and/or ground equipment Product label: Folicur ® 

# 3.6F EPA Reg. No. 264

- 752

Initial Application Date: (day

- month) Fruiting Vegetables: Pepper: FL Pepper: 20

- 10 Tomato: CA Tomato: 21

- 07 PA Tomato: 03

- 09 FL Tomato: 03

- 04 Initial application date based on the Pre

- h arvest Interval of 7 days and 6 applications (42 days before harvest) Crop Scenarios

CAM Input F ruiting Vegetables (all scenarios ) : 2 Foliar applications ( aerial/ground) P E5 User’s Manual

IPSCND Input F ruiting Vegetables (all scenarios ) : 3 R emaining pesticide on foliage is retained as surface residue and continues to decay. P E5 User’s Manual

Application Efficiency Aerial: 0.95 Ground: 0.99 Default value s for foliar spray Guidance for Selecting Input Parameters in Modeling the Environmental Fate and Transport of Pesticides; Feb 28, 2002 Spray Drift Fraction Aerial: 0. 05 Ground: 0.0 1 Default values for foliar spray Guidance for Selecting Input Parameter s in Modeling the Environmental Fate and Transport of Pesticides; Feb 28, 2002 Molecular Weight (g/mol) 308 Product c hemistry data N/A 1



# Henry’s Law Constant at 20 °C (atm

- m 3 

# /mol) 1.24 x 10 - 10 

# Calculated D269918

# 6 Ta ble 3. PRZM/EXAMS Input P arameters for Tebuconazole

. Input Parameter Value Comment Source Vapor Pressure at 20°C (mm Hg ) 1.3 x 10 - 8 

# Product chemistry data MRID (GLN 63

- 9)

Solubi lity in Water at 20 o 

# C (mg/L) 2 

# 32 Product chemistry data MRID (GLN 63

- 7)

Organic Carbon Partition Coefficient (K OC 

# ) ( mL/g ) 1023 Represents the average K OC 

# MRIDs: 40995922 and 40700960 (GLN 163

- 1) Hydrolysis: Half

- life (days) 0 (stable) Stable at pH 5, 7, 9 MRID 40700957 (GLN 161

- 1)

Aqueous Photolysis Half

- life at pH 7 (days) 590 C alculated MRID 40700958 (GLN 161

- 2)

Aerobic Aquatic Metabolism Half

- life (days) 1592 Assumed 2 x aerobic soil metabolism half

- li fe input value (MRID 40700959) because the compound is stable to hydrolysis and no aerobic aquatic metabolism data are available Guidance for Selecting Input Parameters in Modeling the Environmental Fate and Transport of Pesticides; Feb 28, 2002

Anaerobi c Aquatic Metabolism Half

- life (days) 2126 Assumed 2 x anaerobic soil metabolism half

- life input value (MRID 40700959) because the compound is stable to hydrolysis and no anaerobic aquatic metabolism data are available Guidance for Selecting Input Paramet ers in Modeling the Environmental Fate and Transport of Pesticides; Feb 28, 2002

Aerobic Soil Metabolism Half

- life (days) 796

-- MRID 40700959 (GLN 162

- 1)

Ana erobic Soil Metabolism Half

- life (days) 1063

-- MRID 40700959



# Foliar Dissipation Rate PLDK RT 0.078 Calculated
Foliar half

- lives ranged from 1.2 to 8.4 days. The upper confidence bound on the mean met abolism half

- life was 8.90 days. For calculation of PLDKRT input parameter refer to Appendix B

. MRID 46574201

1 

# N/A means not applicable

. 2 

# (3 .6 lbs. a.i./gallon)(gallon/128 fl. oz.)(8 fl. oz./acre) = 0.225 lbs. a.i./acre = 0.253 kg/ha 3 

# For modeling, the solubility value was multiplied by 10 for the input parameter.



# 3.2. 2 Model Outputs: Aquatic Exposure Estimates

Maximum 1

- in

- 10 year surface water EEC values derived from PRZM/EXAMS for each of the modeled crop scenarios are summarized in Table 4 . In general, aerial applications of tebuconazole resulted in higher EECs compared to grou nd applications for Folicur® 3.6F. Tebuconazole peak EEC leve ls for aeri al applications ranged from 19.48 ppb for the CA tomato scenario to 104.6 ppb for the FL Pepper scenario. For ground applications, peak EECs ranged from 5.49 ppb for the CA tomato scenario to 98.23 ppb for the FL Pepper scenario. PRZM/EXAMS ou tput files are provided in Appendix A for the parent tebuconazole

.

# 7 Table 4 . Tebuconazole Estimated Environmental Concentrations (EECs) for Surface Water based on selected Crop Scenarios

Proposed Label Use PRZM/EXAMS Scenario (first app date) Method 1 

# Ap plication Rate (interval between

applications) Peak EEC ( μg/L) 21

- day EEC ( μg/L) 60

- day EEC ( μg/L)

Folicur ® 

# 3.6F Fruiting Vegetables (Crop Group 8) FL Pepper (October 20

– foliar) A 6 app @ 0.225 lb a.i./acre (7 days) 104.60 102.63 98.24

G 98.23 96. 12 91.80

CA Tomato (July 21

– foliar) A 6 app @ 0.225 lb a.i./acre (7 days) 19.48 19.19 18.76

G 5.49 5.41 5.33

PA Tomato (September 03

– foliar) A 6 app @ 0.225 lb a.i./acre (7 days) 70.48 69.67 68.76

G 56.21 55.39 54.24

FL Tomato (April 03

– foliar) A 6 app @ 0.225 lb a.i./acre (7 days) 101.00 98.94 96.65

G 94.91 92.45 90.21 Bold value denotes highest Estimated Environmental Concentrations (EECs)

1 

# For foliar applications, A = aerial application, G = ground application. All appl ications are l iquid unless otherwise noted

.



# 3.3. Exposures to Terrestrial Organisms

Estimated residues on food items that may be consumed by bird and mammals were calculated using T

- REX, version 1.4.1. Inputs used in the modeling are presented in Table 5

. A foliar dissipation half

- life of 9.5 days was used based on available foliar dissipation data presented in Appendix B

. Estimated residue levels on potential food items are presented in Table 6 for birds and Table 7 for mammals

.

Table 5. Inputs U sed in T

- REX

Chemical Name: Tebuconazole

Use: Fruiting Vegetables Application Rate (lbs/A): 0.225

Half

- life (days): 9.5 (upper 95 th 

# percent confidence interval on the mean from values presented in Appendix B) Application Interval (days): 7

Num ber of Applications: 6

# 8 Table 6 . Avian Exposure Concentration Estimates for Tebuconazole A pplications to Fruiting Vegetables (6 applications at 0.225 lb a.i./acre)

Feeding Category Dietary

- based EECs (mg/kg

food item) Dose

- based EECs (mg/kg

- bw) Sma ll (20 g) Medium (100 g) Large (1000 g) Short grass 129 146.59 83.59 37.43 Tall grass 59 67.19 38.31 17.15 Broadleaf plants/small insects 72 82.46 47.02 21.05 Fruits/pods/seeds/large insects 8.0 9.16 5.22 2.34 Granivores

- 2.04 1.16 0.52



# Table 7 . Ma mmalian Exposure Concentration Estimates for Tebuconazole Applications to Fruiting Vegetables (6 applications at 0.225 lb a.i./acre )

Feeding Category Dietary

- based EECs (mg/kg

food item) Dose

- based EECs (mg/kg

- bw) Small (15 g) Medium (35 g) Large (1000 g) Short grass 129 122.72 84.82 19.66 Tall grass 59 56.25 38.87 9.01 Broadleaf plants/small insects 72 69.03 47.71 11.06 Fruits/pods/seeds/large insects 8.0 7.67 5.30 1.23 Granivores

- 1.70 1.18 0.27



# 4. Ecological Effects Summary

4.1. Submitted Ec otoxicity Studies

Toxicity data used to calculate RQs for tebuconazole are included in Table s 8 and 9

. A new toxicity study that evaluated the effects of tebuconazole on the seedling emergence of terrestrial plants (MRID 472992

- 01) was received and revie wed since the last assessment

. A seedling emergence endpoint for a dicot (tomato) from this newly submitted st udy is included in Table 9

, below

. All other toxicity data used in the current assessment has been previously reviewed and described (see D333331 for details)

.

# 9 Table 8 . Summary of Acute and Chronic Aquatic Toxicity Data Used in Risk Characterization

Species Acute Toxicity Chronic Toxicity

EC/LC 50 

# (μg ai/L) Acute Toxicity Classification (MRID) NOAEC / LOAEC (μg ai/L) Affected Endpoints

(MR ID)

Rainbow Trout Oncorhynchus mykiss 2270 Moderately toxic (469192

- 04) NOAEC = 12 LOAEC = 25 Early life stage test indicated reduced larval survival (407009

- 14)

Water flea Daphnia magna 2880 Moderately toxic (469192

- 05) NOAEC = 120 LOAEC = 230 R educed adult length, survival, and young and adult reproduction (407009

- 15)

Sheepshead minnow Cyprinodon variegatus 5900 Moderately toxic (409959

- 04) NOAEC = 21.9 LOAEC = 47.5 Reduced larval weight (420382

- 02)

Eastern Oyster Crassostrea virgi nica 2700 Moderately Toxic (409959

- 03) -- --

Mysid shrimp Americamysis bahia 490 Highly Toxic (409959

- 02) NOAEC = 35 LOAEC = 61 Reduced reproductive

success (42039201)

Duckweed Lemna gibba 151.5 NOAEC = 34.2 Frond Density (442469

- 01)

Green algae Scen edesmus subspicatus 1450 NOAEC = 320 Cell dry weight (409959

- 08)

# 10 Table 9 . Summary of Acute and Chronic Terrestrial Toxicity Data used in Risk Assessment

Species Acute Toxicity Chronic Toxicity

LD 50 

# Acute Oral Toxicity (MRID) LC 50 

# Subacute Di etary Toxicity (MRID) NOAEC / LOAEC Affected Endpoints

(MRID)

Bobwhite quail 1988 mg/kg bw Slightly Toxic 407009

- 05 NOAEC = 73.5 mg ai/kg

- diet

LOAEC = > 73.5 mg ai/kg

- diet No treatment related effects were observed at any test level (407009

- 10)

Mal lard duck > 4815 mg/kg diet Slightly to practically

non

- toxic 407009

- 07

Laboratory rat 1615 mg ai/kg

- bwt S lightly T oxic (420900

- 06)

Laboratory rat NOAEC = 300 mg ai/kg

- diet

LOAEC = 1000 mg ai/kg

- diet decreased maternal and pup body wei ght, decreased pup viability (407009

- 46)

Terrestrial Plants Seedling Emergence Monocot (wheat): EC 25 

# > 0.404 lb a.i./A, NOAEC < 0.404 lb a.i./A Dicot (tomato): EC 25 

# = 0.0 45 lb a.i./A, EC05 = 0.01 6 lb a.i./A * Vegetative Vigor Monocot (wheat): EC 25 

# > 0.404 lb a.i./A, NOAEC < 0.404 lb a.i./A Dicot (cucumber): EC 25 

# > 0.404 lb a.i./A, NOAEC < 0.404 lb a.i./A 458213

- 01 (Tier I) 458213

- 02 (Tier II) 472992

- 01 * (Tier II)

* The dicot endpoint is based on a study that was not previously used in risk assessment.



# Two studies that evaluated the acute risks to honeybees and earthworms are currently under review.

# 11 4.2. Review of Incident Data

Incident information from the Ecological Incident Information System (EIIS) database was available and indicated that se ven incidents occurred in conjunction with the use of tebuconazole. One of these incidents resulted in a fish kill while the other six reported damage to wheat

, soybean plants, and soybean seeds. Tebuconazole cannot be associated with these incidents wit h a great deal of certainty because environmental residue data were not reported at any of these sites. All events were rated “possible” on the certainty index as opposed to probable or highly probable and no residue analysis was available.

O ne aquatic incident (incident # I007892

- 003) was reported in compliance with 6(a)2 regulations about a fish kill in Minnesota on June 25, 1998. An undetermined number of fathead minnows were killed along a long stretch of a creek adjacent to two wheat fields that h ad been treated (one by aircraft) with Folicur. This incident was rated as “possible” because of the low acute toxicity of tebuconazole to fish. In addition, no data with regard to application rates was available.

Regarding the six incidents to terres trial plants, one was the result of a “misuse” situation (incident # I015152

- 001) where a formulator added tebuconazole to a 790 gallon lot of a mixture of quintozene, thiabendazol, and captan on March 12, 2004. This created a formulation of an unregister ed end

- use product for a soybean seed treatment which was used by about 10 commercial seed treating companies in IL, IN, OH, MI, and LA. Stunt ed growth was observed on May 21, 2004

, and growers were consequently instructed to destroy their crops. Damage t o about 1950 acres of soybeans from the use of tebuconazole in conjunction with unknown adjuvant(s) resulted plant stress and yellowing (incident # I016595

- 031, I0016595

- 032). Another incident with soybean occurred when damage was caused by high heat and the application of tebuconazole (incident # I0116737

- 021). Damage to spring wheat resulted from a reported “off label use” of tebuconazole (incident # I016662

- 021, I016662

- 022). Leaf and head malformation were observed.

5

. Ecological Risks Summary

5 .1. Terrestrial Organisms

RQs used to estimate potential risks to aquatic and terrestrial organisms are in Table s 10 to 14

. Dose

- based RQs exceeded LOCs for listed small birds consuming short grass for acute exposures (highest acute RQ = 0.10

, Table 10 ) and for l isted and n on

- listed small birds consuming short grass for chronic exposures (highest chronic RQ = 1. 75

, Table 12 ).

Dose

- based RQs did not exceed acute LOCs for any size class of mammal consuming any food item ( Table 13 ). However, t he chronic LOC was exceeded for small, medium, and large mammals consuming short grass and small and medium mammals consuming tall grass and broadleaf plants/small inesects (highest RQ = 3.7 2

, Table 1 4 ).

Reducing the number of applications to 2 (0.225 lbs a.i./Acre) wi th a 14

- day application interval reduces RQs to below the LOC for birds. However, RQs would remain above the LOC for mammals. A single application at rates of 0.14 lbs a.i/Acre and lower would not result in LOC

# 12 exceedances for mammals.

The LOC for li sted and non

- listed plants was also exceeded ( Table 1 5 ) with an RQ of 3.5 2 and 1. 25 , respectively, for listed and non

- listed species in semi

- aquatic environments

.

Table 10 . Upper Bound Kenaga, Acute Avian Dose

- Based Risk Quotients (6 Applications at 0 .225 lbs a.i./Acre, 7

- day Interval)

Size Class

(grams) Adjusted LD50 EECs and RQs

Short Grass Tall Grass Broadleaf Plants/ Small Insects Fruits/Pods/ Seeds/ Large Insects Granivore

EEC RQ EEC RQ EEC RQ EEC RQ EEC RQ

20 1432 146.59 0.10 * 67.19 0.05 82.46 0.06 9.16 0.01 2.04 <0.01

100 1823 83.59 0.05 38.31 0.02 47.02 0.03 5.22 <0.01 1.16 <0.01

1000 2575 37.43 0.01 17.15 0.01 21.05 0.01 2.34 <0.01 0.52 <0.01

*Exceeds acute ES LOC of 0.1 **Exceeds acute restricted use LOC of 0.2 ***Exceeds acute LOC of 0.5



# Table 11 . Upper Bound Kenaga, Subacute Avian Dietary Based Risk Quotients

LC50 EECs and RQs

Short Grass Tall Grass Broadleaf Plants/ Small Insects Fruits/Pods/ Seeds/ Large Insects

EEC RQ EEC RQ EEC RQ EEC RQ

4815 128.71 0.03 58.99 0.01 7 2.40 0.02 8.04 < 0.0 1



# Table 12 . Upper Bound Kenaga, Chronic Avian Dietary Based Risk Quotients

NOAEC (ppm) EECs and RQs

Short Grass Tall Grass Broadleaf Plants/ Small Insects Fruits/Pods/ Seeds/ Large Insects

EEC RQ EEC RQ EEC RQ EEC RQ

74 128.71 1.75 + 58.99 0.80 72.40 0.99 8.04 0.11

+Exceeds chronic LOC of 1.0

# 13 Table 13 . Upper Bound Kenaga, Acute Mammalian Dose

- Based Risk Quotients

Size Class

(grams) Adjusted LD 50 

# EECs and RQs

Short Grass Tall Grass Broadleaf Plants/ Small Insects Fruit s/Pods/ Seeds/ Large Insects Granivore

EEC RQ EEC RQ EEC RQ EEC RQ EEC RQ 15 3549.50 122.72 0.03 56.25 0.02 69.03 0.02 7.67 <0.01 1.70 <0.01 35 2871.92 84.82 0.03 38.87 0.01 47.71 0.02 5.30 <0.01 1.18 <0.01 1000 1242.19 19.66 0.02 9.01 0.01 11.06 0.0 1 1.23 <0.01 0.27 <0.01



# Table 14 . Upper Bound Kenaga, Chronic Mammalian Dose

- Based Risk Quotients

Size Class

(grams) Adjusted NOAEL EECs and RQs

Short Grass Tall Grass Broadleaf Plants/ Small Insects Fruits/Pods/ Seeds/ Large Insects Granivore

E EC RQ EEC RQ EEC RQ EEC RQ EEC RQ 15 32.97 122.72 3.72 + 56.25 1.71 + 69.03 2.09 + 7.67 0.23 1.70 0.05 35 26.67 84.82 3.18 + 38.87 1.46 + 47.71 1.79 + 5.30 0.20 1.18 0.04 1000 11.54 19.66 1.70 + 9.01 0.78 11.06 0.96 1.23 0.11 0.27 0.02 +Exceeds chronic LOC of 1.0



# Table 15 . RQ values for plants in dry and semi

- aquatic areas exposed to Tebuconazole through runoff and/or spray drift.* Plant Type Listed Status Dry Semi

- Aquatic Spray Drift

Monocot non

- listed <0.1 0.14 <0.1 Monocot listed <0.1 0.14 <0.1

Dico t non

- listed 0.35 1.25 * 0.25 Dicot listed 0.98 3.52 * 0.70
*Exceeds LOC of 1.0



# 5.2. Aquatic Organisms

Aquatic RQs are summarized in Tables 16 and 17

. Except for the aerial FL Pepper scenario freshwater fish acute RQ meeting the acute endangered spec ies LOC (0.05), a cute RQs did not exceed LOCs for freshwater or saltwater fish, aquatic plants, or freshwater invertebrates. However, acute RQs exceeded the acute restricted use LOC for saltwater invertebrates for all scenarios except both the ground and aerial CA Tomato scenario . C hronic RQ s exceeded the LOC of 1 .0 for all proposed uses for freshwater fish except the ground CA Tomato scenario

.

# 14 Chronic RQs exceeded the LOC for saltwater fish and invertebrates for all scenarios except both the ground and ae rial CA Tomato scenario.

Table 16

. Freshwater Organism RQs for Tebuconazole

Proposed Label Use PRZM/ EXAMS Scenario Method Acute RQs Chronic RQs

Peak EEC (μg/L) Fish RQ ( LC50 =

2270 ug/L ) Invert. RQ ( EC50 =

2880 ug/L ) Plant RQ ( EC50 = 150 ug/L ) 21

- day EEC (μg/L) 60

- day EEC (μg/L) Fish RQ ( NOAEC

= 12 ug/L ) Invert

. RQ ( NOAEC = 120 ug/L )

Fruiting Vegetables (Crop Group 8) FL Pepper A 104.60 0.0 5* 0.0 4 0.0 7 102.63 98.24 8.19 + 0.86

G 98.23 0.04 0.03 0.65 96.12 91.80 7.65 + 0.80

CA Tomato A 19.48 0.0 1 0.0 1 0.13 19.19 18.76 1.56 + 0.16 G 5.49 < 0.0 1 < 0.0 1 0.0 4 5.41 5.33 0.44 0.05 PA Tomato A 70.48 0.03 0.02 0.47 69.67 68.76 5.73 + 0.58 G 56.21 0.02 0.02 0.37 55.39 54.24 4.52 + 0.46 FL Tomato A 101.00 0.04 0.0 4 0.67 98.94 96.65 8.05 + 0.82 G 94.91 0.04 0.03 0.63 92.45 90.21 7.52 + 0.77 *Exceeds acute ES LOC of 0.05 +Exceeds chronic LOC of 1.0



# Table 17

. Saltwater Organism RQs for Tebuconazole

Proposed Label Use PRZM/ EXAMS Scenario Method Acute RQs Chronic RQs

Peak EEC (μg/L) Fish RQ ( LC50 =

5900 ug/L ) Invert. RQ ( EC50 =

490 ug/L ) Oyster RQ ( EC50 =

2700 ug/L ) 21

- day EEC (μg/L) 60

- day EEC (μg/L) Fish RQ ( NOAEC =

22 ug/L ) Invert

. RQ ( NOAEC =

35 ug/L )

Fruiting Vegetables (Crop Group 8) FL Pepper A 104.60 0.02 0.21 ** 0.04 102.63 98.24 4.47 + 2.81 +

G 98.23 0.02 0.20 ** 0.04 96.12 91.80 4.17 + 2.62 +

CA Tomato A 19.48 <0.01 0.04 0.01 19.19 18.76 0.85 0.54 G 5.49 <0.01 0.01 0.00 5.41 5.33 0.24 0.15 PA Tomato A 70.48 0.01 0.14 ** 0.03 69.67 68.76 3.13 + 1.96 + G 56.21 0.01 0.11 ** 0.02 55.39 54.24 2.47 + 1.55 + FL Tomato A 101.00 0.02 0.21 ** 0.04 98.94 96.65 4.39 + 2.76 + G 94.91 0.02 0.19 ** 0.04 92.45 90.21 4.10 + 2.58 + *Exceeds acute ES LOC of 0.05 **Exceeds acute restricted use LOC of 0.1 ***Exceeds acute LOC of 0.5 +Exceeds chronic LOC of 1.0

# 15 6. Data Gaps

S ince the 2007 assessment was conducted, submission of an acute oral toxicity study o n a passerine species was included in the Part 158 data requirements. Therefore, a data gap exist s for the acute oral study in a passerine sp ecies. In addition, EFED has identified issues with the terrestrial plant toxicity studies. A submitted Tier I seedling emergence and vegetative vigor study (MRID 458213

- 01) was classified as supplemental because the product was not tested at the maximum ( single application) label use rate. The concentration tested was 0.404 lb a.i./acre, while Folicur 3.6F is registered for use on dry bulb vegetables to control white rot at a maximum single application rate of 0.564 lb a.i./acre (EPA Reg. No. 265

- 752, stam ped June 17, 2009). While this current action proposes a single application rate of 0.225 lb a.i./acre and, therefore, the aforementioned study would satisfy data requirements, EFED recognizes a Tier I seedling emergence and vegetative vigor study using th e rate of 0.564 lb a.i./acre as a data gap for certain uses that have already been registered. Pending the results of a new Tier I study, it may be possible to upgrade the submitted Tier II studies (MRID 458213

- 02, 472992

- 01) to an acceptable
status.

7. Endangered and Threatened Species

T able 18 summarizes the conclusions of potential concerns for direct and indirect effects to federally

- listed threatened and endangered species (listed species). Also, LOCATES is used to identify listed species that may be located within the same county as the proposed new uses. Results of the LOCATES query are included in Appendix C

.

Table 18 . Potential Effects to Federally Listed Taxa

Listed Taxa Direct Effects Indirect Effects

Terrestrial and semi

- aquatic plant s

- monocots No Yes (risks to pollinators such as birds and mammals and other plants) Terrestrial and semi

- aquatic plants

- dicots Yes Terrestrial invertebrates No Yes (risks to terrestrial plants)

Birds Yes Yes (risks to terrestrial plants, fish, aqua tic invertebrates, birds and mammals) Terrestrial phase amphibians Yes Yes (risks to terrestrial plants, birds, and mammals)

Reptiles Yes Yes (risks to fish, aquatic invertebrates, terrestrial plants, birds, and mammals)

Mammals Yes Yes (risks to terr estrial plants, birds, aquatic invertebrates, birds, and other mammals) Aquatic vascular plants No Yes (risks to terrestrial plants, fish, and aquatic invertebrates)

Freshwater fish Yes Yes (risks to terrestrial plants, aquatic invertebrates, other fish) Aquatic phase amphibians Yes Yes (risks to terrestrial plants,

# 16 Table 18 . Potential Effects to Federally Listed Taxa

Listed Taxa Direct Effects Indirect Effects aquatic invertebrates, other fish)

Freshwater crustaceans Yes Yes (risks to terrestrial plants, fish, aquatic invertebrates)

Mollusks No Yes (risks to terrestrial plants, fish, aquatic i nvertebrates)

Marine/estuarine fish Yes Yes (risks to terrestrial plants, aquatic invertebrates, other fish)

Marine/estuarine invertebrates Yes Yes (risks to terrestrial plants, fish, aquatic invertebrates)

# 17 Appendix A : PRZM/EXAM Outputs

# 18 stored as FLpepper aerial eco.out Chemical: Tebuconazole PRZM environment: FLpeppersSTD.txt modified Tueday, 26 August 2008 at 06:16:37 EXAMS environment: pond298.exv modified Tueday, 26 August 2008 at 06:14:07 Metfile: w12844.dvf modified Tueday, 26 August 2008 at 06:14:21 Water segment concentrations (ppb)

Year Peak 96 hr 21 Day 60 Day 90 Day Yearly 1961 3.94 3.828 3.588 3.203 2.318 0.5716 1962 9.583 9.495 8.75 8.548 7.89 6.131 1963 22.25 17.18 15.05 14.08 12.9 10.79 1964 34.04 33.65 32.86 29.15 25.93 21.33 1965 37.44 37.15 36.75 35.87 33.01 28.84 1966 44.2 43.83 42.64 41.31 40.56 38.92 1967 43.29 43.1 42.49 42.12 41.77 41.12 1968 45.47 45.29 44.95 44.14 43.61 42.37 1969 54.07 53.78 53.16 51.98 49.82 47.22 1970 60.29 60.08 59.06 58.17 57.4 54.7 1971 68.56 67.91 66.4 63.82 60.09 55.04 1972 71.62 71.16 69.76 66.86 63.52 60.78 1973 65.85 65.66 65.3 64.91 64.57 62.45 1974 73.96 73.4 72.26 69.79 69 65.31 1975 67.05 66.88 66.26 65.28 64.76 63.06 1976 67.76 67.49 66.95 65.75 65.15 63.61 1977 79.62 79.1 77.31 72.39 69.78 67.59 1978 82.13 81.53 80.15 78.72 74.89 72.08 1979 80.73 80.5 79.51 77.94 77.15 75.51 1980 81.92 81.63 80.75 80.04 79.48 76.18 1981 79.97 79.18 78.43 76.68 75.13 73.7 1982 91.35 90.89 89.74 86.93 83.05 79.93 1983 92.84 92.39 91.34 89.9 88.89 84.72 1984 117 116 112 100 93.69 87.19 1985 101 101 99.32 97.29 96.75 93.92 1986 107 106 104 98.34 97.7 94.02 1987 105 105 103 100 99.68 95.81 1988 97.74 97.54 97.11 96.31 96.15 92.81 1989 91.99 91.76 90.98 89.39 88.82 86.48 1990 85.95 85.78 85.38 84.48 84.17 81.66

Sorted results Prob. Peak 96 hr 21 Day 60 Day 90 Day Yearly 0.03 117.00 116.00 112.00 100.00 99.68 95.81 0.06 107.00 106.00 104.00 100.00 97.70 94.02 0.10 105.00 105.00 103.00 98.34 96.75 93.92 0.13 101.00 101.00 99.32 97.29 96.15 92.81 0.16 97.74 97.54 97.11 96.31 93.69 87.19 0.19 92.84 92.39 91.34 89.90 88.89 86.48 0.23 91.99 91.76 90.98 89.39 88.82 84.72 0.26 91.35 90.89 89.74 86.93 84.17 81.66 0.29 85.95 85.78 85.38 84.48 83.05 79.93 0.32 82.13 81.63 80.75 80.04 79.48 76.18 0.35 81.92 81.53 80.15 78.72 77.15 75.51 0.39 80.73 80.50 79.51 77.94 75.13 73.70 0.42 79.97 79.18 78.43 76.68 74.89 72.08 0.45 79.62 79.10 77.31 72.39 69.78 67.59 0.48 73.96 73.40 72.26 69.79 69.00 65.31 0.52 71.62 71.16 69.76 66.86 65.15 63.61 0.55 68.56 67.91 66.95 65.75 64.76 63.06 0.58 67.76 67.49 66.40 65.28 64.57 62.45 0.61 67.05 66.88 66.26 64.91 63.52 60.78 0.65 65.85 65.66 65.30 63.82 60.09 55.04 0.68 60.29 60.08 59.06 58.17 57.40 54.70 0.71 54.07 53.78 53.16 51.98 49.82 47.22 0.74 45.47 45.29 44.95 44.14 43.61 42.37 0.77 44.20 43.83 42.64 42.12 41.77 41.12 0.81 43.29 43.10 42.49 41.31 40.56 38.92 0.84 37.44 37.15 36.75 35.87 33.01 28.84 0.87 34.04 33.65 32.86 29.15 25.93 21.33 0.90 22.25 17.18 15.05 14.08 12.90 10.79 0.94 9.58 9.50 8.75 8.55 7.89 6.13 0.97 3.94 3.83 3.59 3.20 2.32 0.57

0.10 104.60 104.60 102.63 98.24 96.69 93.81 Average of yea 60.79

Inputs generated by pe5.pl - Novemeber 2006

Data used for this run: Output File: FLpepper aerial eco Metfile: w12844.dvf PRZM scenario: FLpeppersSTD.txt EXAMS environment file: pond298.exv Chemical Name: Tebuconazole Description Variable Name Value Units Comments Molecular weight mwt 308 g/mol Henry's Law Const. henry 1.24E-10 atm-m^3/mol Vapor Pressure vapr 1.30E-08 torr Solubility sol 320 mg/L Kd Kd mg/L Koc Koc 1023 mg/L Photolysis half-life kdp 590 days Half-life Aerobic Aquatic Metabolism kbacw 1592 days Halfife Anaerobic Aquatic Metabolism kbacs 2126 days Halfife Aerobic Soil Metabolism asm 796 days Halfife Hydrolysis: pH 7 0 days Half-life Method: CAM 2 integer See PRZM manual Incorporation Depth: DEPI cm Application Rate: TAPP 0.253 kg/ha Application Efficiency: APPEFF 0.95 fraction Spray Drift DRFT 0.05 fraction of application rate applied to pond Application Date Date 20-10 dd/mm or dd/mmm or dd-mm or dd-mmm Interval 1 interval 7 days Set to 0 or delete line for single app. app. rate 1 apprate kg/ha Interval 2 interval 7 days Set to 0 or delete line for single app. app. rate 2 apprate kg/ha Interval 3 interval 7 days Set to 0 or delete line for single app. app. rate 3 apprate kg/ha Interval 4 interval 7 days Set to 0 or delete line for single app. app. rate 4 apprate kg/ha Interval 5 interval 7 days Set to 0 or delete line for single app. app. rate 5 apprate kg/ha Record 17: FILTRA IPSCND 3 UPTKF Record 18: PLVKRT PLDKRT 0.078 FEXTRC 0.5 Flag for Index Res. Run IR EPA Pond Flag for runoff calc. RUNOFF none none, monthly or total(average of entire run)

# 19 stored as FLpepper ground eco.out Chemical: Tebuconazole PRZM environment: FLpeppersSTD.txt modified Tueday, 26 August 2008 at 06:16:37 EXAMS environment: pond298.exv modified Tueday, 26 August 2008 at 06:14:07 Metfile: w12844.dvf modified Tueday, 26 August 2008 at 06:14:21 Water segment concentrations (ppb)

Year Peak 96 hr 21 Day 60 Day 90 Day Yearly 1961 1.713 1.652 1.627 1.529 1.091 0.269 1962 7.097 7.033 6.278 5.994 5.86 4.799 1963 19.37 14.07 11.72 10.64 9.912 8.557 1964 30.04 29.78 29.01 25.43 22.57 18.58 1965 33.9 33.55 32.85 31.66 29.16 25.56 1966 40.88 40.51 39.29 37.94 37.19 35.31 1967 39.22 39.03 38.5 38.09 37.76 36.94 1968 41.13 40.94 40.6 39.79 39.26 37.63 1969 47.66 47.42 47.01 45.99 44.21 42.14 1970 55.33 55.11 54.05 53.16 52.4 49.46 1971 62.89 62.26 60.27 57.54 54.12 49.42 1972 65.87 65.31 63.41 60.46 57.45 55.13 1973 59.8 59.62 59.31 58.95 58.67 56.62 1974 68.04 67.47 66.34 63.87 63.11 59.37 1975 60.45 60.29 59.74 58.86 58.4 56.81 1976 61.39 61.12 60.55 59.2 58.8 57.13 1977 72.65 72.15 70.33 65.09 62.87 61.06 1978 75.09 74.52 72.86 71.51 67.99 65.55 1979 74.11 73.82 72.88 71.59 70.83 68.97 1980 75.38 75.08 74.18 73.41 72.88 69.54 1981 72.68 72.08 70.86 69.01 68.18 66.84 1982 84.1 83.62 82.47 79.65 76.07 73.27 1983 86.32 85.87 84.8 83.4 82.41 78.2 1984 111 109 105 93.35 86.98 80.69 1985 94.53 94.14 92.79 90.81 90.35 87.63 1986 100 99.53 97.41 91.91 91.31 87.68 1987 98.64 98.17 96.49 94.02 93.32 89.54 1988 91.04 90.85 90.41 89.7 89.6 86.38 1989 85.55 85.32 84.53 82.95 82.24 79.8 1990 78.68 78.52 78.15 77.37 77.13 74.8

Sorted results Prob. Peak 96 hr 21 Day 60 Day 90 Day Yearly 0.03 111.00 109.00 105.00 94.02 93.32 89.54 0.06 100.00 99.53 97.41 93.35 91.31 87.68 0.10 98.64 98.17 96.49 91.91 90.35 87.63 0.13 94.53 94.14 92.79 90.81 89.60 86.38 0.16 91.04 90.85 90.41 89.70 86.98 80.69 0.19 86.32 85.87 84.80 83.40 82.41 79.80 0.23 85.55 85.32 84.53 82.95 82.24 78.20 0.26 84.10 83.62 82.47 79.65 77.13 74.80 0.29 78.68 78.52 78.15 77.37 76.07 73.27 0.32 75.38 75.08 74.18 73.41 72.88 69.54 0.35 75.09 74.52 72.88 71.59 70.83 68.97 0.39 74.11 73.82 72.86 71.51 68.18 66.84 0.42 72.68 72.15 70.86 69.01 67.99 65.55 0.45 72.65 72.08 70.33 65.09 63.11 61.06 0.48 68.04 67.47 66.34 63.87 62.87 59.37 0.52 65.87 65.31 63.41 60.46 58.80 57.13 0.55 62.89 62.26 60.55 59.20 58.67 56.81 0.58 61.39 61.12 60.27 58.95 58.40 56.62 0.61 60.45 60.29 59.74 58.86 57.45 55.13 0.65 59.80 59.62 59.31 57.54 54.12 49.46 0.68 55.33 55.11 54.05 53.16 52.40 49.42 0.71 47.66 47.42 47.01 45.99 44.21 42.14 0.74 41.13 40.94 40.60 39.79 39.26 37.63 0.77 40.88 40.51 39.29 38.09 37.76 36.94 0.81 39.22 39.03 38.50 37.94 37.19 35.31 0.84 33.90 33.55 32.85 31.66 29.16 25.56 0.87 30.04 29.78 29.01 25.43 22.57 18.58 0.90 19.37 14.07 11.72 10.64 9.91 8.56 0.94 7.10 7.03 6.28 5.99 5.86 4.80 0.97 1.71 1.65 1.63 1.53 1.09 0.27

0.10 98.23 97.77 96.12 91.80 90.28 87.51 Average of yea 55.46

Inputs generated by pe5.pl - Novemeber 2006

Data used for this run: Output File: FLpepper ground eco Metfile: w12844.dvf PRZM scenario: FLpeppersSTD.txt EXAMS environment file: pond298.exv Chemical Name: Tebuconazole Description Variable Name Value Units Comments Molecular weight mwt 308 g/mol Henry's Law Const. henry 1.24E-10 atm-m^3/mol Vapor Pressure vapr 1.30E-08 torr Solubility sol 320 mg/L Kd Kd mg/L Koc Koc 1023 mg/L Photolysis half-life kdp 590 days Half-life Aerobic Aquatic Metabolism kbacw 1592 days Halfife Anaerobic Aquatic Metabolism kbacs 2126 days Halfife Aerobic Soil Metabolism asm 796 days Halfife Hydrolysis: pH 7 0 days Half-life Method: CAM 2 integer See PRZM manual Incorporation Depth: DEPI cm Application Rate: TAPP 0.253 kg/ha Application Efficiency: APPEFF 0.99 fraction Spray Drift DRFT 0.01 fraction of application rate applied to pond Application Date Date 20-10 dd/mm or dd/mmm or dd-mm or dd-mmm Interval 1 interval 7 days Set to 0 or delete line for single app. app. rate 1 apprate kg/ha Interval 2 interval 7 days Set to 0 or delete line for single app. app. rate 2 apprate kg/ha Interval 3 interval 7 days Set to 0 or delete line for single app. app. rate 3 apprate kg/ha Interval 4 interval 7 days Set to 0 or delete line for single app. app. rate 4 apprate kg/ha Interval 5 interval 7 days Set to 0 or delete line for single app. app. rate 5 apprate kg/ha Record 17: FILTRA IPSCND 3 UPTKF Record 18: PLVKRT PLDKRT 0.078 FEXTRC 0.5 Flag for Index Res. Run IR EPA Pond Flag for runoff calc. RUNOFF none none, monthly or total(average of entire run)

# 20 stored as CAtomato aerial eco.out Chemical: Tebuconazole PRZM environment: CAtomato_WirrigSTD.txt modified Tueday, 26 August 2008 at 06:16:36 EXAMS environment: pond298.exv modified Tueday, 26 August 2008 at 06:14:07 Metfile: w93193.dvf modified Tueday, 26 August 2008 at 06:16:12 Water segment concentrations (ppb)

Year Peak 96 hr 21 Day 60 Day 90 Day Yearly 1961 2.907 2.821 2.556 2.235 2.068 0.8222 1962 4.532 4.444 4.179 3.851 3.681 2.471 1963 5.972 5.883 5.617 5.282 5.113 3.944 1964 7.236 7.146 6.88 6.544 6.392 5.268 1965 8.584 8.493 8.227 7.888 7.705 6.608 1966 9.596 9.504 9.236 8.889 8.703 7.654 1967 10.56 10.47 10.2 9.846 9.657 8.636 1968 11.37 11.28 11.01 10.66 10.49 9.482 1969 12.35 12.25 11.98 11.62 11.43 10.45 1970 13.11 13.02 12.75 12.39 12.2 11.26 1971 13.81 13.72 13.45 13.08 12.89 11.94 1972 14.36 14.26 13.99 13.63 13.44 12.57 1973 15.11 15.01 14.74 14.38 14.19 13.29 1974 15.59 15.5 15.22 14.84 14.65 13.77 1975 16.09 16 15.72 15.35 15.15 14.25 1976 16.84 16.77 16.52 16.34 16.26 15.17 1977 17.63 17.53 17.26 16.88 16.67 15.86 1978 17.86 17.77 17.62 17.3 17.09 16.18 1979 18.38 18.28 18.01 17.62 17.4 16.62 1980 18.51 18.41 18.14 17.76 17.55 16.74 1981 18.54 18.44 18.16 17.78 17.57 16.82 1982 18.72 18.62 18.34 18 17.82 17 1983 19.18 19.08 18.81 18.42 18.21 17.45 1984 19.13 19.03 18.75 18.36 18.13 17.43 1985 19.05 18.95 18.69 18.32 18.13 17.41 1986 19.37 19.27 18.99 18.62 18.41 17.69 1987 19.53 19.43 19.16 18.77 18.55 17.79 1988 19.48 19.38 19.11 18.72 18.5 17.75 1989 19.48 19.38 19.11 18.76 18.56 17.77 1990 19.65 19.55 19.27 18.89 18.67 17.93

Sorted results Prob. Peak 96 hr 21 Day 60 Day 90 Day Yearly 0.03 19.65 19.55 19.27 18.89 18.67 17.93 0.06 19.53 19.43 19.16 18.77 18.56 17.79 0.10 19.48 19.38 19.11 18.76 18.55 17.77 0.13 19.48 19.38 19.11 18.72 18.50 17.75 0.16 19.37 19.27 18.99 18.62 18.41 17.69 0.19 19.18 19.08 18.81 18.42 18.21 17.45 0.23 19.13 19.03 18.75 18.36 18.13 17.43 0.26 19.05 18.95 18.69 18.32 18.13 17.41 0.29 18.72 18.62 18.34 18.00 17.82 17.00 0.32 18.54 18.44 18.16 17.78 17.57 16.82 0.35 18.51 18.41 18.14 17.76 17.55 16.74 0.39 18.38 18.28 18.01 17.62 17.40 16.62 0.42 17.86 17.77 17.62 17.30 17.09 16.18 0.45 17.63 17.53 17.26 16.88 16.67 15.86 0.48 16.84 16.77 16.52 16.34 16.26 15.17 0.52 16.09 16.00 15.72 15.35 15.15 14.25 0.55 15.59 15.50 15.22 14.84 14.65 13.77 0.58 15.11 15.01 14.74 14.38 14.19 13.29 0.61 14.36 14.26 13.99 13.63 13.44 12.57 0.65 13.81 13.72 13.45 13.08 12.89 11.94 0.68 13.11 13.02 12.75 12.39 12.20 11.26 0.71 12.35 12.25 11.98 11.62 11.43 10.45 0.74 11.37 11.28 11.01 10.66 10.49 9.48 0.77 10.56 10.47 10.20 9.85 9.66 8.64 0.81 9.60 9.50 9.24 8.89 8.70 7.65 0.84 8.58 8.49 8.23 7.89 7.71 6.61 0.87 7.24 7.15 6.88 6.54 6.39 5.27 0.90 5.97 5.88 5.62 5.28 5.11 3.94 0.94 4.53 4.44 4.18 3.85 3.68 2.47 0.97 2.91 2.82 2.56 2.24 2.07 0.82

0.10 19.48 19.38 19.11 18.76 18.55 17.77 Average of yea 12.93

Inputs generated by pe5.pl - Novemeber 2006

Data used for this run: Output File: CAtomato aerial eco Metfile: w93193.dvf PRZM scenario: CAtomato_WirrigSTD.txt EXAMS environment file: pond298.exv Chemical Name: Tebuconazole Description Variable Name Value Units Comments Molecular weight mwt 308 g/mol Henry's Law Const. henry 1.24E-10 atm-m^3/mol Vapor Pressure vapr 1.30E-08 torr Solubility sol 320 mg/L Kd Kd mg/L Koc Koc 1023 mg/L Photolysis half-life kdp 590 days Half-life Aerobic Aquatic Metabolism kbacw 1592 days Halfife Anaerobic Aquatic Metabolism kbacs 2126 days Halfife Aerobic Soil Metabolism asm 796 days Halfife Hydrolysis: pH 7 0 days Half-life Method: CAM 2 integer See PRZM manual Incorporation Depth: DEPI cm Application Rate: TAPP 0.253 kg/ha Application Efficiency: APPEFF 0.95 fraction Spray Drift DRFT 0.05 fraction of application rate applied to pond Application Date Date 21-07 dd/mm or dd/mmm or dd-mm or dd-mmm Interval 1 interval 7 days Set to 0 or delete line for single app. app. rate 1 apprate kg/ha Interval 2 interval 7 days Set to 0 or delete line for single app. app. rate 2 apprate kg/ha Interval 3 interval 7 days Set to 0 or delete line for single app. app. rate 3 apprate kg/ha Interval 4 interval 7 days Set to 0 or delete line for single app. app. rate 4 apprate kg/ha Interval 5 interval 7 days Set to 0 or delete line for single app. app. rate 5 apprate kg/ha Record 17: FILTRA IPSCND 3 UPTKF Record 18: PLVKRT PLDKRT 0.078 FEXTRC 0.5 Flag for Index Res. Run IR EPA Pond Flag for runoff calc. RUNOFF none none, monthly or total(average of entire run)

# 21 stored as CAtomato ground eco.out Chemical: Tebuconazole PRZM environment: CAtomato_WirrigSTD.txt modified Tueday, 26 August 2008 at 06:16:36 EXAMS environment: pond298.exv modified Tueday, 26 August 2008 at 06:14:07 Metfile: w93193.dvf modified Tueday, 26 August 2008 at 06:16:12 Water segment concentrations (ppb)

Year Peak 96 hr 21 Day 60 Day 90 Day Yearly 1961 0.59 0.58 0.52 0.46 0.42 0.18 1962 1.07 1.05 1.00 0.93 0.90 0.66 1963 1.45 1.43 1.38 1.31 1.28 1.06 1964 1.83 1.82 1.78 1.74 1.67 1.39 1965 2.21 2.19 2.14 2.07 2.03 1.83 1966 2.42 2.40 2.35 2.27 2.23 2.05 1967 2.66 2.64 2.59 2.51 2.47 2.29 1968 2.81 2.79 2.74 2.67 2.66 2.47 1969 3.15 3.13 3.08 3.00 2.96 2.79 1970 3.37 3.35 3.30 3.22 3.18 3.03 1971 3.54 3.52 3.46 3.39 3.35 3.18 1972 3.80 3.78 3.72 3.62 3.53 3.31 1973 3.94 3.92 3.86 3.79 3.75 3.60 1974 4.03 4.01 3.95 3.87 3.84 3.70 1975 4.13 4.11 4.06 3.98 3.94 3.79 1976 5.42 5.37 5.20 5.00 4.93 4.32 1977 5.03 5.01 4.95 4.87 4.82 4.71 1978 5.42 5.39 5.28 5.12 5.07 4.83 1979 5.39 5.37 5.31 5.23 5.18 5.08 1980 5.34 5.32 5.26 5.18 5.13 5.01 1981 5.26 5.23 5.18 5.10 5.05 4.95 1982 5.27 5.26 5.21 5.18 5.14 4.94 1983 5.49 5.47 5.41 5.34 5.30 5.21 1984 5.43 5.41 5.35 5.27 5.22 5.13 1985 5.39 5.37 5.34 5.27 5.21 5.06 1986 5.57 5.55 5.49 5.41 5.36 5.28 1987 5.60 5.58 5.53 5.45 5.40 5.30 1988 5.47 5.45 5.39 5.31 5.26 5.16 1989 5.38 5.36 5.31 5.26 5.22 5.09 1990 5.46 5.44 5.38 5.30 5.25 5.15

Sorted results Prob. Peak 96 hr 21 Day 60 Day 90 Day Yearly 0.03 5.60 5.58 5.53 5.45 5.40 5.30 0.06 5.57 5.55 5.49 5.41 5.36 5.28 0.10 5.49 5.47 5.41 5.34 5.30 5.21 0.13 5.47 5.45 5.39 5.31 5.26 5.16 0.16 5.46 5.44 5.38 5.30 5.25 5.15 0.19 5.43 5.41 5.35 5.27 5.22 5.13 0.23 5.42 5.39 5.34 5.27 5.22 5.09 0.26 5.42 5.37 5.31 5.26 5.21 5.08 0.29 5.39 5.37 5.31 5.23 5.18 5.06 0.32 5.39 5.37 5.28 5.18 5.14 5.01 0.35 5.38 5.36 5.26 5.18 5.13 4.95 0.39 5.34 5.32 5.21 5.12 5.07 4.94 0.42 5.27 5.26 5.20 5.10 5.05 4.83 0.45 5.26 5.23 5.18 5.00 4.93 4.71 0.48 5.03 5.01 4.95 4.87 4.82 4.32 0.52 4.13 4.11 4.06 3.98 3.94 3.79 0.55 4.03 4.01 3.95 3.87 3.84 3.70 0.58 3.94 3.92 3.86 3.79 3.75 3.60 0.61 3.80 3.78 3.72 3.62 3.53 3.31 0.65 3.54 3.52 3.46 3.39 3.35 3.18 0.68 3.37 3.35 3.30 3.22 3.18 3.03 0.71 3.15 3.13 3.08 3.00 2.96 2.79 0.74 2.81 2.79 2.74 2.67 2.66 2.47 0.77 2.66 2.64 2.59 2.51 2.47 2.29 0.81 2.42 2.40 2.35 2.27 2.23 2.05 0.84 2.21 2.19 2.14 2.07 2.03 1.83 0.87 1.83 1.82 1.78 1.74 1.67 1.39 0.90 1.45 1.43 1.38 1.31 1.28 1.06 0.94 1.07 1.05 1.00 0.93 0.90 0.66 0.97 0.59 0.58 0.52 0.46 0.42 0.18

0.10 5.49 5.47 5.41 5.33 5.29 5.20 Average of y 3.68

Inputs generated by pe5.pl - Novemeber 2006

Data used for this run: Output File: CAtomato ground eco Metfile: w93193.dvf PRZM scenario: CAtomato_WirrigSTD.txt EXAMS environment file: pond298.exv Chemical Name: Tebuconazole Description Variable Nam Value Units Comments Molecular weight mwt 308 g/mol Henry's Law Const. henry 1.24E-10 atm-m^3/mol Vapor Pressure vapr 1.30E-08 torr Solubility sol 320 mg/L Kd Kd mg/L Koc Koc 1023 mg/L Photolysis half-life kdp 590 days Half-life Aerobic Aquatic Metabolism kbacw 1592 days Halfife Anaerobic Aquatic Metabolism kbacs 2126 days Halfife Aerobic Soil Metabolism asm 796 days Halfife Hydrolysis: pH 7 0 days Half-life Method: CAM 2 integer See PRZM manual Incorporation Depth: DEPI cm Application Rate: TAPP 0.253 kg/ha Application Efficiency: APPEFF 0.99 fraction Spray Drift DRFT 0.01 fraction of application rate applied to pond Application Date Date 21-07 dd/mm or dd/mmm or dd-mm or dd-mmm Interval 1 interval 7 days Set to 0 or delete line for single app. app. rate 1 apprate kg/ha Interval 2 interval 7 days Set to 0 or delete line for single app. app. rate 2 apprate kg/ha Interval 3 interval 7 days Set to 0 or delete line for single app. app. rate 3 apprate kg/ha Interval 4 interval 7 days Set to 0 or delete line for single app. app. rate 4 apprate kg/ha Interval 5 interval 7 days Set to 0 or delete line for single app. app. rate 5 apprate kg/ha Record 17: FILTRA IPSCND 3 UPTKF Record 18: PLVKRT PLDKRT 0.078 FEXTRC 0.5 Flag for Index Res. Run IR EPA Pond Flag for runoff calc. RUNOFF none none, monthly or total(average of entire run)

# 22 stored as PAtomato aerial eco.out Chemical: Tebuconazole PRZM environment: PAtomatoSTD.txt modified Tueday, 26 August 2008 at 06:16:42 EXAMS environment: pond298.exv modified Tueday, 26 August 2008 at 06:14:07 Metfile: w14751.dvf modified Tueday, 26 August 2008 at 06:14:59 Water segment concentrations (ppb)

Year Peak 96 hr 21 Day 60 Day 90 Day Yearly 1961 3.027 2.984 2.759 2.655 2.587 0.7529 1962 10.92 10.75 10.39 10.18 9.946 4.975 1963 14.8 14.69 14.51 13.9 13.25 10.26 1964 16.73 16.66 16.47 16.08 16.06 14.34 1965 20.32 20.18 19.74 19.12 18.86 17.24 1966 25.69 25.5 25.23 24.86 24.81 21.13 1967 28.74 28.61 28.33 28.11 27.76 25.35 1968 32.9 32.76 32.44 32.31 32.29 28.69 1969 34.69 34.6 34.37 33.63 33.46 31.64 1970 37 36.85 36.55 36.4 36.06 34.24 1971 39.47 39.38 39.11 37.99 37.52 35.95 1972 42.98 42.8 42.62 41.86 40.75 38.42 1973 46.68 46.53 45.3 44.48 44.33 41.57 1974 47.19 47.1 46.71 46.14 46.1 45.02 1975 64.39 63.66 61.81 59.21 58.04 48.94 1976 68.46 67.91 66.76 64.68 63.52 56.58 1977 63.45 63.36 63.04 62.71 62.56 61.23 1978 63 62.93 62.78 62.66 62.58 61.53 1979 66.87 66.66 66.29 65.51 65.15 63.06 1980 66.83 66.68 66.16 65.64 64.99 63.55 1981 66.66 66.51 66.01 65.61 65.4 64.53 1982 65.9 65.79 65.38 65.11 65.02 64.39 1983 67.72 67.58 67.17 66.23 65.8 64.4 1984 66.94 66.85 66.54 66.13 65.97 64.87 1985 67.48 67.38 67.25 66.65 66.7 64.81 1986 66.92 66.82 66.38 66.06 66.06 65.22 1987 70.65 70.46 69.81 68.81 68.4 65.78 1988 68.94 68.81 68.38 68.32 68.19 67.11 1989 72.33 72.06 71.12 70.04 69.29 67.1 1990 71.59 71.37 70.81 70.59 70 68.17

Sorted results Prob. Peak 96 hr 21 Day 60 Day 90 Day Yearly 0.03 72.33 72.06 71.12 70.59 70.00 68.17 0.06 71.59 71.37 70.81 70.04 69.29 67.11 0.10 70.65 70.46 69.81 68.81 68.40 67.10 0.13 68.94 68.81 68.38 68.32 68.19 65.78 0.16 68.46 67.91 67.25 66.65 66.70 65.22 0.19 67.72 67.58 67.17 66.23 66.06 64.87 0.23 67.48 67.38 66.76 66.13 65.97 64.81 0.26 66.94 66.85 66.54 66.06 65.80 64.53 0.29 66.92 66.82 66.38 65.64 65.40 64.40 0.32 66.87 66.68 66.29 65.61 65.15 64.39 0.35 66.83 66.66 66.16 65.51 65.02 63.55 0.39 66.66 66.51 66.01 65.11 64.99 63.06 0.42 65.90 65.79 65.38 64.68 63.52 61.53 0.45 64.39 63.66 63.04 62.71 62.58 61.23 0.48 63.45 63.36 62.78 62.66 62.56 56.58 0.52 63.00 62.93 61.81 59.21 58.04 48.94 0.55 47.19 47.10 46.71 46.14 46.10 45.02 0.58 46.68 46.53 45.30 44.48 44.33 41.57 0.61 42.98 42.80 42.62 41.86 40.75 38.42 0.65 39.47 39.38 39.11 37.99 37.52 35.95 0.68 37.00 36.85 36.55 36.40 36.06 34.24 0.71 34.69 34.60 34.37 33.63 33.46 31.64 0.74 32.90 32.76 32.44 32.31 32.29 28.69 0.77 28.74 28.61 28.33 28.11 27.76 25.35 0.81 25.69 25.50 25.23 24.86 24.81 21.13 0.84 20.32 20.18 19.74 19.12 18.86 17.24 0.87 16.73 16.66 16.47 16.08 16.06 14.34 0.90 14.80 14.69 14.51 13.90 13.25 10.26 0.94 10.92 10.75 10.39 10.18 9.95 4.98 0.97 3.03 2.98 2.76 2.66 2.59 0.75

0.10 70.48 70.30 69.67 68.76 68.38 66.97 Average of yea 45.36

Inputs generated by pe5.pl - Novemeber 2006

Data used for this run: Output File: PAtomato aerial eco Metfile: w14751.dvf PRZM scenario: PAtomatoSTD.txt EXAMS environment file: pond298.exv Chemical Name: Tebuconazole Description Variable Name Value Units Comments Molecular weight mwt 308 g/mol Henry's Law Const. henry 1.24E-10 atm-m^3/mol Vapor Pressure vapr 1.30E-08 torr Solubility sol 320 mg/L Kd Kd mg/L Koc Koc 1023 mg/L Photolysis half-life kdp 590 days Half-life Aerobic Aquatic Metabolism kbacw 1592 days Halfife Anaerobic Aquatic Metabolism kbacs 2126 days Halfife Aerobic Soil Metabolism asm 796 days Halfife Hydrolysis: pH 7 0 days Half-life Method: CAM 2 integer See PRZM manual Incorporation Depth: DEPI cm Application Rate: TAPP 0.253 kg/ha Application Efficiency: APPEFF 0.95 fraction Spray Drift DRFT 0.05 fraction of application rate applied to pond Application Date Date 3/9 dd/mm or dd/mmm or dd-mm or dd-mmm Interval 1 interval 7 days Set to 0 or delete line for single app. app. rate 1 apprate kg/ha Interval 2 interval 7 days Set to 0 or delete line for single app. app. rate 2 apprate kg/ha Interval 3 interval 7 days Set to 0 or delete line for single app. app. rate 3 apprate kg/ha Interval 4 interval 7 days Set to 0 or delete line for single app. app. rate 4 apprate kg/ha Interval 5 interval 7 days Set to 0 or delete line for single app. app. rate 5 apprate kg/ha Record 17: FILTRA IPSCND 3 UPTKF Record 18: PLVKRT PLDKRT 0.078 FEXTRC 0.5 Flag for Index Res. Run IR EPA Pond Flag for runoff calc. RUNOFF none none, monthly or total(average of entire run)

# 23 stored as PAtomato ground eco.out Chemical: Tebuconazole PRZM environment: PAtomatoSTD.txt modified Tueday, 26 August 2008 at 06:16:42 EXAMS environment: pond298.exv modified Tueday, 26 August 2008 at 06:14:07 Metfile: w14751.dvf modified Tueday, 26 August 2008 at 06:14:59 Water segment concentrations (ppb)

Year Peak 96 hr 21 Day 60 Day 90 Day Yearly 1961 1.731 1.693 1.462 1.238 0.9889 0.2668 1962 8.593 8.474 8.07 7.835 7.414 3.382 1963 11.56 11.45 11.26 10.55 9.69 7.687 1964 12.4 12.34 12.2 11.73 11.53 10.82 1965 14.22 14.15 13.93 13.61 13.44 12.79 1966 19.61 19.52 19.26 18.77 18.69 15.89 1967 21.93 21.86 21.67 21.39 20.89 19.37 1968 25.9 25.7 25.13 24.77 24.77 21.99 1969 26.8 26.71 26.49 25.6 25.23 24.26 1970 28.2 28.11 27.9 27.68 27.24 26.23 1971 30.38 30.3 30.03 28.78 28.1 27.34 1972 33.32 33.16 32.93 32.17 30.82 29.26 1973 36.77 36.62 35.31 34.32 33.97 31.93 1974 36.73 36.64 36.24 35.88 35.64 34.98 1975 53.71 53 50.71 48.21 47.15 38.52 1976 56.8 56.3 55.35 53.52 52.4 45.99 1977 52.21 52.12 51.79 51.3 51.01 50.35 1978 51.81 51.75 51.58 51.49 51.43 50.22 1979 54.05 53.88 53.48 52.96 52.74 51.39 1980 54.37 54.23 53.75 53.09 52.28 51.52 1981 54.22 54.13 53.84 53.45 53.25 52.18 1982 52.82 52.76 52.57 52.47 52.41 51.63 1983 54.34 54.2 53.8 52.68 52.03 51.3 1984 53.6 53.51 53.21 52.83 52.68 51.47 1985 53.35 53.28 53.11 52.5 52.31 51.1 1986 52.66 52.57 52.3 52.2 52.16 51.24 1987 56.19 56.01 55.39 54.27 53.64 51.59 1988 54.28 54.21 54.06 54.01 53.91 52.77 1989 56.89 56.66 55.86 54.97 54.13 52.53 1990 56.21 56.06 55.52 55.42 54.69 53.45

Sorted results Prob. Peak 96 hr 21 Day 60 Day 90 Day Yearly 0.03 56.89 56.66 55.86 55.42 54.69 53.45 0.06 56.80 56.30 55.52 54.97 54.13 52.77 0.10 56.21 56.06 55.39 54.27 53.91 52.53 0.13 56.19 56.01 55.35 54.01 53.64 52.18 0.16 54.37 54.23 54.06 53.52 53.25 51.63 0.19 54.34 54.21 53.84 53.45 52.74 51.59 0.23 54.28 54.20 53.80 53.09 52.68 51.52 0.26 54.22 54.13 53.75 52.96 52.41 51.47 0.29 54.05 53.88 53.48 52.83 52.40 51.39 0.32 53.71 53.51 53.21 52.68 52.31 51.30 0.35 53.60 53.28 53.11 52.50 52.28 51.24 0.39 53.35 53.00 52.57 52.47 52.16 51.10 0.42 52.82 52.76 52.30 52.20 52.03 50.35 0.45 52.66 52.57 51.79 51.49 51.43 50.22 0.48 52.21 52.12 51.58 51.30 51.01 45.99 0.52 51.81 51.75 50.71 48.21 47.15 38.52 0.55 36.77 36.64 36.24 35.88 35.64 34.98 0.58 36.73 36.62 35.31 34.32 33.97 31.93 0.61 33.32 33.16 32.93 32.17 30.82 29.26 0.65 30.38 30.30 30.03 28.78 28.10 27.34 0.68 28.20 28.11 27.90 27.68 27.24 26.23 0.71 26.80 26.71 26.49 25.60 25.23 24.26 0.74 25.90 25.70 25.13 24.77 24.77 21.99 0.77 21.93 21.86 21.67 21.39 20.89 19.37 0.81 19.61 19.52 19.26 18.77 18.69 15.89 0.84 14.22 14.15 13.93 13.61 13.44 12.79 0.87 12.40 12.34 12.20 11.73 11.53 10.82 0.90 11.56 11.45 11.26 10.55 9.69 7.69 0.94 8.59 8.47 8.07 7.84 7.41 3.38 0.97 1.73 1.69 1.46 1.24 0.99 0.27

0.10 56.21 56.06 55.39 54.24 53.88 52.50 Average of yea 35.78

Inputs generated by pe5.pl - Novemeber 2006

Data used for this run: Output File: PAtomato ground eco Metfile: w14751.dvf PRZM scenario: PAtomatoSTD.txt EXAMS environment file: pond298.exv Chemical Name: Tebuconazole Description Variable Name Value Units Comments Molecular weight mwt 308 g/mol Henry's Law Const. henry 1.24E-10 atm-m^3/mol Vapor Pressure vapr 1.30E-08 torr Solubility sol 320 mg/L Kd Kd mg/L Koc Koc 1023 mg/L Photolysis half-life kdp 590 days Half-life Aerobic Aquatic Metabolism kbacw 1592 days Halfife Anaerobic Aquatic Metabolism kbacs 2126 days Halfife Aerobic Soil Metabolism asm 796 days Halfife Hydrolysis: pH 7 0 days Half-life Method: CAM 2 integer See PRZM manual Incorporation Depth: DEPI cm Application Rate: TAPP 0.253 kg/ha Application Efficiency: APPEFF 0.99 fraction Spray Drift DRFT 0.01 fraction of application rate applied to pond Application Date Date 3/9 dd/mm or dd/mmm or dd-mm or dd-mmm Interval 1 interval 7 days Set to 0 or delete line for single app. app. rate 1 apprate kg/ha Interval 2 interval 7 days Set to 0 or delete line for single app. app. rate 2 apprate kg/ha Interval 3 interval 7 days Set to 0 or delete line for single app. app. rate 3 apprate kg/ha Interval 4 interval 7 days Set to 0 or delete line for single app. app. rate 4 apprate kg/ha Interval 5 interval 7 days Set to 0 or delete line for single app. app. rate 5 apprate kg/ha Record 17: FILTRA IPSCND 3 UPTKF Record 18: PLVKRT PLDKRT 0.078 FEXTRC 0.5 Flag for Index Res. Run IR EPA Pond Flag for runoff calc. RUNOFF none none, monthly or total(average of entire run)

# 24 stored as FLtomato aerial eco.out Chemical: Tebuconazole PRZM environment: FLtomatoSTD.txt modified Tueday, 26 August 2008 at 06:16:38 EXAMS environment: pond298.exv modified Tueday, 26 August 2008 at 06:14:07 Metfile: w12844.dvf modified Tueday, 26 August 2008 at 06:14:21 Water segment concentrations (ppb)

Year Peak 96 hr 21 Day 60 Day 90 Day Yearly 1961 6.38 6.28 6.03 5.65 5.54 3.42 1962 16.42 16.20 15.60 14.74 14.23 10.17 1963 25.77 25.30 24.11 22.02 21.09 17.33 1964 40.50 39.93 38.13 36.47 35.56 28.33 1965 45.28 44.87 43.60 42.25 41.61 35.87 1966 54.37 53.92 52.38 50.64 49.65 43.15 1967 53.66 53.40 52.83 51.50 50.84 46.86 1968 69.66 68.90 68.05 65.30 63.53 54.53 1969 68.79 68.31 67.06 65.10 64.22 59.51 1970 72.72 72.21 70.55 68.83 67.68 62.28 1971 74.82 74.37 73.52 71.43 71.12 65.50 1972 85.60 85.13 84.07 82.74 81.35 72.41 1973 80.70 80.47 79.75 78.87 78.23 73.80 1974 75.29 75.11 74.50 74.11 73.50 71.52 1975 75.77 75.49 74.85 74.36 73.63 69.95 1976 83.52 82.86 80.75 77.98 76.62 71.30 1977 96.75 96.30 94.46 90.67 88.87 79.08 1978 92.39 91.86 90.40 88.19 87.19 81.81 1979 101.00 100.00 98.10 96.51 95.74 87.61 1980 101.00 99.93 98.43 96.47 95.41 89.43 1981 93.74 93.46 92.87 91.74 91.04 88.09 1982 102.00 101.00 99.84 98.20 97.45 90.59 1983 101.00 99.95 99.00 96.66 95.40 89.87 1984 104.00 104.00 101.00 99.63 98.24 91.22 1985 96.77 96.47 95.54 94.37 93.66 90.32 1986 91.75 91.59 91.31 90.45 89.61 86.65 1987 90.77 90.44 89.54 87.91 87.87 84.22 1988 101.00 101.00 98.08 96.34 95.01 87.19 1989 89.46 89.18 88.75 87.66 87.45 85.09 1990 93.06 92.58 91.81 90.86 90.23 84.28

Sorted results Prob. Peak 96 hr 21 Day 60 Day 90 Day Yearly 0.03 104.00 104.00 101.00 99.63 98.24 91.22 0.06 102.00 101.00 99.84 98.20 97.45 90.59 0.10 101.00 101.00 99.00 96.66 95.74 90.32 0.13 101.00 100.00 98.43 96.51 95.41 89.87 0.16 101.00 99.95 98.10 96.47 95.40 89.43 0.19 101.00 99.93 98.08 96.34 95.01 88.09 0.23 96.77 96.47 95.54 94.37 93.66 87.61 0.26 96.75 96.30 94.46 91.74 91.04 87.19 0.29 93.74 93.46 92.87 90.86 90.23 86.65 0.32 93.06 92.58 91.81 90.67 89.61 85.09 0.35 92.39 91.86 91.31 90.45 88.87 84.28 0.39 91.75 91.59 90.40 88.19 87.87 84.22 0.42 90.77 90.44 89.54 87.91 87.45 81.81 0.45 89.46 89.18 88.75 87.66 87.19 79.08 0.48 85.60 85.13 84.07 82.74 81.35 73.80 0.52 83.52 82.86 80.75 78.87 78.23 72.41 0.55 80.70 80.47 79.75 77.98 76.62 71.52 0.58 75.77 75.49 74.85 74.36 73.63 71.30 0.61 75.29 75.11 74.50 74.11 73.50 69.95 0.65 74.82 74.37 73.52 71.43 71.12 65.50 0.68 72.72 72.21 70.55 68.83 67.68 62.28 0.71 69.66 68.90 68.05 65.30 64.22 59.51 0.74 68.79 68.31 67.06 65.10 63.53 54.53 0.77 54.37 53.92 52.83 51.50 50.84 46.86 0.81 53.66 53.40 52.38 50.64 49.65 43.15 0.84 45.28 44.87 43.60 42.25 41.61 35.87 0.87 40.50 39.93 38.13 36.47 35.56 28.33 0.90 25.77 25.30 24.11 22.02 21.09 17.33 0.94 16.42 16.20 15.60 14.74 14.23 10.17 0.97 6.38 6.28 6.03 5.65 5.54 3.42

0.10 101.00 100.90 98.94 96.65 95.71 90.28 Average of yea 66.71

Inputs generated by pe5.pl - Novemeber 2006

Data used for this run: Output File: FLtomato aerial eco Metfile: w12844.dvf PRZM scenario: FLtomatoSTD.txt EXAMS environment file: pond298.exv Chemical Name: Tebuconazole Description Variable Name Value Units Comments Molecular weight mwt 308 g/mol Henry's Law Const. henry 1.24E-10 atm-m^3/mol Vapor Pressure vapr 1.30E-08 torr Solubility sol 320 mg/L Kd Kd mg/L Koc Koc 1023 mg/L Photolysis half-life kdp 590 days Half-life Aerobic Aquatic Metabolism kbacw 1592 days Halfife Anaerobic Aquatic Metabolism kbacs 2126 days Halfife Aerobic Soil Metabolism asm 796 days Halfife Hydrolysis: pH 7 0 days Half-life Method: CAM 2 integer See PRZM manual Incorporation Depth: DEPI cm Application Rate: TAPP 0.253 kg/ha Application Efficiency: APPEFF 0.95 fraction Spray Drift DRFT 0.05 fraction of application rate applied to pond Application Date Date 3/4 dd/mm or dd/mmm or dd-mm or dd-mmm Interval 1 interval 7 days Set to 0 or delete line for single app. app. rate 1 apprate kg/ha Interval 2 interval 7 days Set to 0 or delete line for single app. app. rate 2 apprate kg/ha Interval 3 interval 7 days Set to 0 or delete line for single app. app. rate 3 apprate kg/ha Interval 4 interval 7 days Set to 0 or delete line for single app. app. rate 4 apprate kg/ha Interval 5 interval 7 days Set to 0 or delete line for single app. app. rate 5 apprate kg/ha Record 17: FILTRA IPSCND 3 UPTKF Record 18: PLVKRT PLDKRT 0.078 FEXTRC 0.5 Flag for Index Res. Run IR EPA Pond Flag for runoff calc. RUNOFF none none, monthly or total(average of entire run)

# 25 stored as FLtomato ground eco.out Chemical: Tebuconazole PRZM environment: FLtomatoSTD.txt modified Tueday, 26 August 2008 at 06:16:38 EXAMS environment: pond298.exv modified Tueday, 26 August 2008 at 06:14:07 Metfile: w12844.dvf modified Tueday, 26 August 2008 at 06:14:21 Water segment concentrations (ppb)

Year Peak 96 hr 21 Day 60 Day 90 Day Yearly 1961 5.347 5.238 4.996 4.619 4.516 2.531 1962 14.57 14.35 13.7 12.87 12.39 8.418 1963 22.63 22.17 20.8 18.94 18.13 14.88 1964 37.41 36.83 35.06 33.37 32.49 25.45 1965 42.02 41.6 40.31 38.83 38.21 32.53 1966 50.66 50.2 48.66 46.81 45.86 39.42 1967 49.17 48.92 48.41 47.16 46.52 42.66 1968 65.04 64.29 63.52 60.77 59.03 50.09 1969 63.88 63.4 62.19 60.24 59.34 54.78 1970 67.42 66.92 65.22 63.55 62.45 57.23 1971 69.44 68.99 68.16 65.94 65.53 60.23 1972 80.11 79.66 78.52 77.16 75.75 67.18 1973 75.09 74.86 74.15 73.37 72.7 68.4 1974 69.46 69.32 68.73 68.28 67.69 65.81 1975 69.53 69.26 68.66 68.07 67.42 63.98 1976 76.94 76.3 74.23 71.58 70.29 65.15 1977 90.48 90.03 88.26 84.33 82.56 73.05 1978 86.22 85.68 84.25 82.09 80.99 75.73 1979 94.94 94.04 91.35 89.91 89.31 81.63 1980 93.98 93.34 91.95 90.12 89.14 83.4 1981 87.2 86.84 86.27 85.15 84.56 81.9 1982 95.27 94.76 93.6 91.81 90.81 84.45 1983 94.03 93.46 92.5 90.22 89.04 83.65 1984 97.44 96.96 94.76 93.2 91.89 84.97 1985 90.42 90.12 89.19 87.93 87.13 83.96 1986 84.99 84.68 84.48 83.74 82.87 80.1 1987 83.88 83.56 82.69 81.07 80.73 77.57 1988 94.65 93.85 91.35 89.72 88.39 80.63 1989 82.33 82.09 81.46 80.19 80.1 78.46 1990 86.34 85.86 85.14 83.94 83.43 77.64

Sorted results Prob. Peak 96 hr 21 Day 60 Day 90 Day Yearly 0.03 97.44 96.96 94.76 93.20 91.89 84.97 0.06 95.27 94.76 93.60 91.81 90.81 84.45 0.10 94.94 94.04 92.50 90.22 89.31 83.96 0.13 94.65 93.85 91.95 90.12 89.14 83.65 0.16 94.03 93.46 91.35 89.91 89.04 83.40 0.19 93.98 93.34 91.35 89.72 88.39 81.90 0.23 90.48 90.12 89.19 87.93 87.13 81.63 0.26 90.42 90.03 88.26 85.15 84.56 80.63 0.29 87.20 86.84 86.27 84.33 83.43 80.10 0.32 86.34 85.86 85.14 83.94 82.87 78.46 0.35 86.22 85.68 84.48 83.74 82.56 77.64 0.39 84.99 84.68 84.25 82.09 80.99 77.57 0.42 83.88 83.56 82.69 81.07 80.73 75.73 0.45 82.33 82.09 81.46 80.19 80.10 73.05 0.48 80.11 79.66 78.52 77.16 75.75 68.40 0.52 76.94 76.30 74.23 73.37 72.70 67.18 0.55 75.09 74.86 74.15 71.58 70.29 65.81 0.58 69.53 69.32 68.73 68.28 67.69 65.15 0.61 69.46 69.26 68.66 68.07 67.42 63.98 0.65 69.44 68.99 68.16 65.94 65.53 60.23 0.68 67.42 66.92 65.22 63.55 62.45 57.23 0.71 65.04 64.29 63.52 60.77 59.34 54.78 0.74 63.88 63.40 62.19 60.24 59.03 50.09 0.77 50.66 50.20 48.66 47.16 46.52 42.66 0.81 49.17 48.92 48.41 46.81 45.86 39.42 0.84 42.02 41.60 40.31 38.83 38.21 32.53 0.87 37.41 36.83 35.06 33.37 32.49 25.45 0.90 22.63 22.17 20.80 18.94 18.13 14.88 0.94 14.57 14.35 13.70 12.87 12.39 8.42 0.97 5.35 5.24 5.00 4.62 4.52 2.53

0.10 94.91 94.02 92.45 90.21 89.29 83.93 Average of yea 61.53

Inputs generated by pe5.pl - Novemeber 2006

Data used for this run: Output File: FLtomato ground eco Metfile: w12844.dvf PRZM scenario: FLtomatoSTD.txt EXAMS environment file: pond298.exv Chemical Name: Tebuconazole Description Variable Name Value Units Comments Molecular weight mwt 308 g/mol Henry's Law Const. henry 1.24E-10 atm-m^3/mol Vapor Pressure vapr 1.30E-08 torr Solubility sol 320 mg/L Kd Kd mg/L Koc Koc 1023 mg/L Photolysis half-life kdp 590 days Half-life Aerobic Aquatic Metabolism kbacw 1592 days Halfife Anaerobic Aquatic Metabolism kbacs 2126 days Halfife Aerobic Soil Metabolism asm 796 days Halfife Hydrolysis: pH 7 0 days Half-life Method: CAM 2 integer See PRZM manual Incorporation Depth: DEPI cm Application Rate: TAPP 0.253 kg/ha Application Efficiency: APPEFF 0.99 fraction Spray Drift DRFT 0.01 fraction of application rate applied to pond Application Date Date 3/4 dd/mm or dd/mmm or dd-mm or dd-mmm Interval 1 interval 7 days Set to 0 or delete line for single app. app. rate 1 apprate kg/ha Interval 2 interval 7 days Set to 0 or delete line for single app. app. rate 2 apprate kg/ha Interval 3 interval 7 days Set to 0 or delete line for single app. app. rate 3 apprate kg/ha Interval 4 interval 7 days Set to 0 or delete line for single app. app. rate 4 apprate kg/ha Interval 5 interval 7 days Set to 0 or delete line for single app. app. rate 5 apprate kg/ha Record 17: FILTRA IPSCND 3 UPTKF Record 18: PLVKRT PLDKRT 0.078 FEXTRC 0.5 Flag for Index Res. Run IR EPA Pond Flag for runoff calc. RUNOFF none none, monthly or total(average of entire run)

# 26 APPENDIX B :

Tebuconazole foliar half

- lives. 

# Crop Half

- life 1 

# (days) Location/Formulation MRID Number Wheat Forage 2 

# 1.2 3.6 F/North Dakota 46574201 Soybean Forage 2 

# 8.4 3.6 F/Illinois Soybean Hay 2 

# 5.3 3.6 F Cherries 3 

# 11.6 1.8 5.8 1.2 45 DF/Oregon Washington New York Wisconsin 42763901

17.3 4.3 6.9 45 DF/California Michigan Michigan 42763902

1



# – Presents valid half

- lives; data sets met the criteria (trials with Day 0 values) for calculating a half

- life, and the results of the regression were sta tistically valid (Power ≥ 0.80). Wheat hay and barley dissipation data had a weak fit to the model with the value of power below 0.80, therefore, were excluded.

2



# – Used for calculation of PLDKRT input parameter. The upper confidence bound on the mean me tabolism half

life was 8.90 days (wheat forage, soybean hay, and soybean forage).

PLDKRT input parameter = ln (0.5)/90% upper confidence bound (8.90) = 0.078