**EXHIBIT
        24.1**




**POWER
      OF ATTORNEY**




KNOW
      ALL
      YE PERSONS BY THESE PRESENTS, that the undersigned does hereby make, constitute
      and appoint William H. Koster and Stephen R. Davis, each his attorney-in-fact
      and agent with full power of substitution and resubstitution for him and in
      his
      name, place and stead, in any and all capacities, to execute for him and on
      his
      behalf an Annual Report pursuant to Section 13 of the Securities and Exchange
      Act of 1934, as amended, on Form 10-K relating to the fiscal year ended December
      31, 2006, of Neurogen Corporation (the "Company"), and any and all amendments
      to
      the foregoing Annual Report on Form 10-K, which amendments may make such changes
      in the Annual Report on Form 10-K as such attorney-in-fact deems appropriate,
      and any other documents and instruments incidental thereto, and to file the
      same, with all exhibits thereto and all documents in connection therewith,
      with
      the Securities and Exchange Commission and the National Association of
      Securities Dealers, Inc., granting unto said attorney-in-fact and agent, full
      power and authority to do and perform each and every act and thing requisite
      and
      necessary to be done in and about the premises, as fully to all intents and
      purposes as the undersigned might or could do in person, hereby ratifying and
      confirming all that said attorney-in-fact and agent, or his substitute or
      substitutes, may lawfully do or cause to be done by virtue hereof.




IN
      WITNESS WHEREOF, the undersigned has executed this Power of Attorney this 13th
      day of March, 2007.




/s/
      FELIX
      J. BAKER


----------------------------


Felix
      J.
      Baker




**EXHIBIT
      24.1**




**POWER
      OF ATTORNEY**




KNOW
      ALL
      YE PERSONS BY THESE PRESENTS, that the undersigned does hereby make, constitute
      and appoint William H. Koster and Stephen R. Davis, each his attorney-in-fact
      and agent with full power of substitution and resubstitution for him and in
      his
      name, place and stead, in any and all capacities, to execute for him and on
      his
      behalf an Annual Report pursuant to Section 13 of the Securities and Exchange
      Act of 1934, as amended, on Form 10-K relating to the fiscal year ended December
      31, 2006, of Neurogen Corporation (the "Company"), and any and all amendments
      to
      the foregoing Annual Report on Form 10-K, which amendments may make such changes
      in the Annual Report on Form 10-K as such attorney-in-fact deems appropriate,
      and any other documents and instruments incidental thereto, and to file the
      same, with all exhibits thereto and all documents in connection therewith,
      with
      the Securities and Exchange Commission and the National Association of
      Securities Dealers, Inc., granting unto said attorney-in-fact and agent, full
      power and authority to do and perform each and every act and thing requisite
      and
      necessary to be done in and about the premises, as fully to all intents and
      purposes as the undersigned might or could do in person, hereby ratifying and
      confirming all that said attorney-in-fact and agent, or his substitute or
      substitutes, may lawfully do or cause to be done by virtue hereof.




IN
      WITNESS WHEREOF, the undersigned has executed this Power of Attorney this 13th
      day of March, 2007.




/s/
      JULIAN C. BAKER


----------------------------


Julian
      C.
      Baker




**EXHIBIT
      24.1**




**POWER
      OF ATTORNEY**




KNOW
      ALL
      YE PERSONS BY THESE PRESENTS, that the undersigned does hereby make, constitute
      and appoint William H. Koster and Stephen R. Davis, each his attorney-in-fact
      and agent with full power of substitution and resubstitution for him and in
      his
      name, place and stead, in any and all capacities, to execute for him and on
      his
      behalf an Annual Report pursuant to Section 13 of
      the
      Securities and Exchange Act of 1934, as amended, on Form 10-K relating to the
      fiscal year ended December 31, 2006, of Neurogen Corporation (the "Company"),
      and any and
      all
      amendments to the foregoing Annual Report on Form 10-K, which amendments may
      make such changes in the Annual Report on Form 10-K as such attorney-in-fact
      deems appropriate, and any other documents and instruments incidental thereto,
      and to file the same, with
      all
      exhibits thereto and all documents in connection








therewith,
      with the Securities and Exchange Commission and the National Association of
      Securities Dealers, Inc., granting unto said attorney-in-fact and agent, full
      power and authority to do and perform each and every act and thing requisite
      and
      necessary to be done in and about the premises, as fully to all intents and
      purposes as the undersigned might or could do in person, hereby ratifying and
      confirming all that said attorney-in-fact and agent, or his substitute or
      substitutes, may lawfully do or cause to be done by virtue hereof.





IN
      WITNESS WHEREOF, the undersigned has executed this Power of Attorney this 13th
      day of March, 2007.




/s/
      ERAN
      BROSHY


----------------------------


Eran
      Broshy




**EXHIBIT
      24.1**




**POWER
      OF ATTORNEY**




KNOW
      ALL
      YE PERSONS BY THESE PRESENTS, that the undersigned does hereby make, constitute
      and appoint William H. Koster and Stephen R. Davis, each his attorney-in-fact
      and agent with full power of substitution and resubstitution for him and in
      his
      name, place and stead, in any and all capacities, to execute for him and on
      his
      behalf an Annual Report pursuant to Section 13 of the Securities and Exchange
      Act of 1934, as amended, on Form 10-K relating to the fiscal year ended December
      31, 2006, of Neurogen Corporation (the "Company"), and any and all amendments
      to
      the foregoing Annual Report on Form 10-K, which amendments may make such changes
      in the Annual Report on Form 10-K as such attorney-in-fact deems appropriate,
      and any other documents and instruments incidental thereto, and to file the
      same, with all exhibits thereto and all documents in connection therewith,
      with
      the Securities and Exchange Commission and the National Association of
      Securities Dealers, Inc., granting unto said attorney-in-fact and agent, full
      power and authority to do and perform each and every act and thing requisite
      and
      necessary to be done in and about the premises, as fully to all intents and
      purposes as the undersigned might or could do in person, hereby ratifying and
      confirming all that said attorney-in-fact and agent, or his substitute or
      substitutes, may lawfully do or cause to be done by virtue hereof.




IN
      WITNESS WHEREOF, the undersigned has executed this Power of Attorney this 13th
      day of March, 2007.




/s/
      STEWART HEN


----------------------------


Stewart
      Hen





**EXHIBIT
      24.1**




**POWER
      OF ATTORNEY**




KNOW
      ALL
      YE PERSONS BY THESE PRESENTS, that the undersigned does hereby make, constitute
      and appoint William H. Koster and Stephen R. Davis, each his attorney-in-fact
      and agent with full power of substitution and resubstitution for him and in
      his
      name, place and stead, in any and all capacities, to execute for him and on
      his
      behalf an Annual Report pursuant to Section 13 of the Securities and Exchange
      Act of 1934, as amended, on Form 10-K relating to the fiscal year ended December
      31, 2006, of Neurogen Corporation (the "Company"), and any and all amendments
      to
      the foregoing Annual Report on Form 10-K, which amendments may make such changes
      in the Annual Report on Form 10-K as such attorney-in-fact deems appropriate,
      and any other documents and instruments incidental thereto, and to file the
      same, with all exhibits thereto and all documents in connection therewith,
      with
      the Securities and Exchange Commission and the National Association of
      Securities Dealers, Inc., granting unto said
      attorney-in-fact and agent, full power and authority to do and perform each
      and
      every act and thing requisite and necessary to be done in and about the
      premises, as fully to all intents and purposes as the undersigned might or
      could
      do in person, hereby ratifying and confirming all that said attorney-in-fact
      and
      agent, or his substitute or substitutes, may lawfully do or cause to be done
      by
      virtue hereof.








IN
      WITNESS WHEREOF, the undersigned has executed this Power of Attorney this 13th
      day of March, 2007.




/s/
      JONATHAN S. LEFF


----------------------------


Jonathan
      S. Leff




**EXHIBIT
        24.1**




**POWER
      OF ATTORNEY**




KNOW
      ALL
      YE PERSONS BY THESE PRESENTS, that the undersigned does hereby make, constitute
      and appoint William H. Koster and Stephen R. Davis, each his attorney-in-fact
      and agent with full power of substitution and resubstitution for him and in
      his
      name, place and stead, in any and all capacities, to execute for him and on
      his
      behalf an Annual Report pursuant to Section 13 of the Securities and Exchange
      Act of 1934, as amended, on Form 10-K relating to the fiscal year ended December
      31, 2006, of Neurogen Corporation (the "Company"), and any and all amendments
      to
      the


foregoing
      Annual Report on Form 10-K, which amendments may make such changes in the Annual
      Report on Form 10-K as such attorney-in-fact deems appropriate, and any other
      documents and instruments incidental thereto, and to file the same, with all
      exhibits thereto and all documents in connection therewith, with the Securities
      and Exchange Commission and the National Association of Securities Dealers,
      Inc., granting unto said attorney-in-fact and agent, full power and authority
      to
      do and perform each and every act and thing requisite and necessary to be done
      in and about the premises, as fully to all intents and purposes as the
      undersigned might or could do in person, hereby ratifying and confirming all
      that said attorney-in-fact and agent, or his substitute or substitutes, may
      lawfully do or cause to be done by virtue hereof.




IN
      WITNESS WHEREOF, the undersigned has executed this Power of Attorney this 13th
      day of March, 2007.




/s/
      CRAIG
      SAXTON


----------------------------


Craig
      Saxton




**EXHIBIT
      24.1**




**POWER
      OF ATTORNEY**




KNOW
      ALL
      YE PERSONS BY THESE PRESENTS, that the undersigned does hereby make, constitute
      and appoint William H. Koster and Stephen R. Davis, each his attorney-in-fact
      and agent with full power of substitution and resubstitution for him and in
      his
      name, place and stead, in any and all capacities, to execute for him and on
      his
      behalf an Annual Report pursuant to Section 13 of the Securities and Exchange
      Act of 1934, as amended, on Form 10-K relating to the fiscal year ended December
      31, 2006, of Neurogen Corporation (the "Company"), and any and all amendments
      to
      the foregoing Annual Report on Form 10-K, which amendments may make such changes
      in the Annual Report on Form 10-K as such attorney-in-fact deems appropriate,
      and any other documents and instruments incidental thereto, and to file the
      same, with all exhibits thereto and all documents in connection therewith,
      with
      the Securities and Exchange Commission and the National Association of
      Securities Dealers, Inc., granting unto said attorney-in-fact and agent, full
      power and authority to do and perform each and every act and thing requisite
      and
      necessary to be done in and about the premises, as fully to all intents and
      purposes as the undersigned might or could do in person, hereby ratifying and
      confirming all that said attorney-in-fact and agent, or his substitute or
      substitutes, may lawfully do or cause to be done by virtue hereof.




IN
      WITNESS WHEREOF, the undersigned has executed this Power of Attorney this 13th
      day of March, 2007.




/s/
      JOHN
      SIMON


----------------------------


John
      Simon