EXHIBIT
24.1




POWER
OF ATTORNEY




KNOW ALL
YE PERSONS BY THESE PRESENTS, that the undersigned does hereby make, constitute
and appoint Stephen R. Davis and Thomas Pitler, each his attorney-in-fact and
agent with full power of substitution and resubstitution for him and in his
name, place and stead, in any and all capacities, to execute for him and on his
behalf an Annual Report pursuant to Section 13 of the Securities and Exchange
Act of 1934, as amended, on Form 10-K relating to the fiscal year ended December
31, 2007, of Neurogen Corporation (the "Company"), and any and all amendments to
the foregoing Annual Report on Form 10-K, which amendments may make such changes
in the Annual Report on Form 10-K as such attorney-in-fact deems appropriate,
and any other documents and instruments incidental thereto, and to file the
same, with all exhibits thereto and all documents in connection therewith, with
the Securities and Exchange Commission and the National Association of
Securities Dealers, Inc., granting unto said attorney-in-fact and agent, full
power and authority to do and perform each and every act and thing requisite and
necessary to be done in and about the premises, as fully to all intents and
purposes as the undersigned might or could do in person, hereby ratifying and
confirming all that said attorney-in-fact and agent, or his substitute or
substitutes, may lawfully do or cause to be done by virtue hereof.




IN
WITNESS WHEREOF, the undersigned has executed this Power of Attorney this 14th
day of March, 2008.




/s/ FELIX
J. BAKER


----------------------------


Felix J.
Baker




EXHIBIT
24.1




POWER
OF ATTORNEY




KNOW ALL
YE PERSONS BY THESE PRESENTS, that the undersigned does hereby make, constitute
and appoint Stephen R. Davis and Thomas Pitler, each his attorney-in-fact and
agent with full power of substitution and resubstitution for him and in his
name, place and stead, in any and all capacities, to execute for him and on his
behalf an Annual Report pursuant to Section 13 of the Securities and Exchange
Act of 1934, as amended, on Form 10-K relating to the fiscal year ended December
31, 2007, of Neurogen Corporation (the "Company"), and any and all amendments to
the foregoing Annual Report on Form 10-K, which amendments may make such changes
in the Annual Report on Form 10-K as such attorney-in-fact deems appropriate,
and any other documents and instruments incidental thereto, and to file the
same, with all exhibits thereto and all documents in connection therewith, with
the Securities and Exchange Commission and the National Association of
Securities Dealers, Inc., granting unto said attorney-in-fact and agent, full
power and authority to do and perform each and every act and thing requisite and
necessary to be done in and about the premises, as fully to all intents and
purposes as the undersigned might or could do in person, hereby ratifying and
confirming all that said attorney-in-fact and agent, or his substitute or
substitutes, may lawfully do or cause to be done by virtue hereof.




IN
WITNESS WHEREOF, the undersigned has executed this Power of Attorney this 14th
day of March, 2008.




/s/
JULIAN C. BAKER


----------------------------


Julian C.
Baker




EXHIBIT
24.1




POWER
OF ATTORNEY




KNOW ALL
YE PERSONS BY THESE PRESENTS, that the undersigned does hereby make, constitute
and appoint Stephen R. Davis and Thomas Pitler, each his attorney-in-fact and
agent with full power of substitution and resubstitution for him and in his
name, place and stead, in any and all capacities, to execute for him and on his
behalf an Annual Report pursuant to Section 13 of the Securities and Exchange
Act of 1934, as amended, on Form 10-K relating to the fiscal year ended December
31, 2007, of Neurogen Corporation (the "Company"), and any and all amendments to
the foregoing Annual Report on Form 10-K, which amendments may make such changes
in the Annual Report on Form 10-K as such attorney-in-fact deems appropriate,
and any other documents and instruments incidental thereto, and to file the
same, with all exhibits thereto and all documents in connection therewith, with
the Securities and Exchange Commission and the National Association of
Securities Dealers, Inc., granting unto said attorney-in-fact and agent, full
power and authority to do and perform each and every act and thing requisite and
necessary to be done in and about the premises, as fully to all intents and
purposes as the undersigned might or could do in person, hereby ratifying and
confirming all that said attorney-in-fact and agent, or his substitute or
substitutes, may lawfully do or cause to be done by virtue hereof.




IN
WITNESS WHEREOF, the undersigned has executed this Power of Attorney this 14th
day of March, 2008.




/s/ ERAN
BROSHY


----------------------------


Eran
Broshy




EXHIBIT
24.1




POWER
OF ATTORNEY




KNOW ALL
YE PERSONS BY THESE PRESENTS, that the undersigned does hereby make, constitute
and appoint Stephen R. Davis and Thomas Pitler, each his attorney-in-fact and
agent with full power of substitution and resubstitution for him and in his
name, place and stead, in any and all capacities, to execute for him and on his
behalf an Annual Report pursuant to Section 13 of the Securities and Exchange
Act of 1934, as amended, on Form 10-K relating to the fiscal year ended December
31, 2007, of Neurogen Corporation (the "Company"), and any and all amendments to
the foregoing Annual Report on Form 10-K, which amendments may make such changes
in the Annual Report on Form 10-K as such attorney-in-fact deems appropriate,
and any other documents and instruments incidental thereto, and to file the
same, with all exhibits thereto and all documents in connection therewith, with
the Securities and Exchange Commission and the National Association of
Securities Dealers, Inc., granting unto said attorney-in-fact and agent, full
power and authority to do and perform each and every act and thing requisite and
necessary to be done in and about the premises, as fully to all intents and
purposes as the undersigned might or could do in person, hereby ratifying and
confirming all that said attorney-in-fact and agent, or his substitute or
substitutes, may lawfully do or cause to be done by virtue hereof.




IN
WITNESS WHEREOF, the undersigned has executed this Power of Attorney this 14th
day of March, 2008.




/s/
STEWART HEN


----------------------------


Stewart
Hen





EXHIBIT
24.1




POWER
OF ATTORNEY




KNOW ALL
YE PERSONS BY THESE PRESENTS, that the undersigned does hereby make, constitute
and appoint Stephen R. Davis and Thomas Pitler, each his attorney-in-fact and
agent with full power of substitution and resubstitution for him and in his
name, place and stead, in any and all capacities, to execute for him and on his
behalf an Annual Report pursuant to Section 13 of the Securities and Exchange
Act of 1934, as amended, on Form 10-K relating to the fiscal year ended December
31, 2007, of Neurogen Corporation (the "Company"), and any and all amendments to
the foregoing Annual Report on Form 10-K, which amendments may make such changes
in the Annual Report on Form 10-K as such attorney-in-fact deems appropriate,
and any other documents and instruments incidental thereto, and to file the
same, with all exhibits thereto and all documents in connection therewith, with
the Securities and Exchange Commission and the National Association of
Securities Dealers, Inc., granting unto said attorney-in-fact and agent, full
power and authority to do and perform each and every act and thing requisite and
necessary to be done in and about the premises, as fully to all intents and
purposes as the undersigned might or could do in person, hereby ratifying and
confirming all that said attorney-in-fact and agent, or his substitute or
substitutes, may lawfully do or cause to be done by virtue hereof.




IN
WITNESS WHEREOF, the undersigned has executed this Power of Attorney this 14th
day of March, 2008.




/s/
WILLIAM H. KOSTER


----------------------------


William
H. Koster





EXHIBIT
24.1




POWER
OF ATTORNEY




KNOW ALL
YE PERSONS BY THESE PRESENTS, that the undersigned does hereby make, constitute
and appoint Stephen R. Davis and Thomas Pitler, each his attorney-in-fact and
agent with full power of substitution and resubstitution for him and in his
name, place and stead, in any and all capacities, to execute for him and on his
behalf an Annual Report pursuant to Section 13 of the Securities and Exchange
Act of 1934, as amended, on Form 10-K relating to the fiscal year ended December
31, 2007, of Neurogen Corporation (the "Company"), and any and all amendments to
the foregoing Annual Report on Form 10-K, which amendments may make such changes
in the Annual Report on Form 10-K as such attorney-in-fact deems appropriate,
and any other documents and instruments incidental thereto, and to file the
same, with all exhibits thereto and all documents in connection therewith, with
the Securities and Exchange Commission and the National Association of
Securities Dealers, Inc., granting unto said attorney-in-fact and agent, full
power and authority to do and perform each and every act and thing requisite and
necessary to be done in and about the premises, as fully to all intents and
purposes as the undersigned might or could do in person, hereby ratifying and
confirming all that said attorney-in-fact and agent, or his substitute or
substitutes, may lawfully do or cause to be done by virtue hereof.




IN
WITNESS WHEREOF, the undersigned has executed this Power of Attorney this 14th
day of March, 2008.




/s/ JOHN
L. LAMATTINA


----------------------------------


John L.
LaMattina





EXHIBIT
24.1




POWER
OF ATTORNEY




KNOW ALL
YE PERSONS BY THESE PRESENTS, that the undersigned does hereby make, constitute
and appoint Stephen R. Davis and Thomas Pitler, each his attorney-in-fact and
agent with full power of substitution and resubstitution for him and in his
name, place and stead, in any and all capacities, to execute for him and on his
behalf an Annual Report pursuant to Section 13 of the Securities and Exchange
Act of 1934, as amended, on Form 10-K relating to the fiscal year ended December
31, 2007, of Neurogen Corporation (the "Company"), and any and all amendments to
the foregoing Annual Report on Form 10-K, which amendments may make such changes
in the Annual Report on Form 10-K as such attorney-in-fact deems appropriate,
and any other documents and instruments incidental thereto, and to file the
same, with all exhibits thereto and all documents in connection therewith, with
the Securities and Exchange Commission and the National Association of
Securities Dealers, Inc., granting unto said attorney-in-fact and agent, full
power and authority to do and perform each and every act and thing requisite and
necessary to be done in and about the premises, as fully to all intents and
purposes as the undersigned might or could do in person, hereby ratifying and
confirming all that said attorney-in-fact and agent, or his substitute or
substitutes, may lawfully do or cause to be done by virtue hereof.




IN WITNESS WHEREOF, the undersigned has
executed this Power of Attorney this 14th day of March, 2008.




/s/
JONATHAN S. LEFF


----------------------------


Jonathan
S. Leff






POWER
OF ATTORNEY




KNOW ALL
YE PERSONS BY THESE PRESENTS, that the undersigned does hereby make, constitute
and appoint Stephen R. Davis and Thomas Pitler, each his attorney-in-fact and
agent with full power of substitution and resubstitution for him and in his
name, place and stead, in any and all capacities, to execute for him and on his
behalf an Annual Report pursuant to Section 13 of the Securities and Exchange
Act of 1934, as amended, on Form 10-K relating to the fiscal year ended December
31, 2007, of Neurogen Corporation (the "Company"), and any and all amendments to
the foregoing Annual Report on Form 10-K, which amendments may make such changes
in the Annual Report on Form 10-K as such attorney-in-fact deems appropriate,
and any other documents and instruments incidental thereto, and to file the
same, with all exhibits thereto and all documents in connection therewith, with
the Securities and Exchange Commission and the National Association of
Securities Dealers, Inc., granting unto said attorney-in-fact and agent, full
power and authority to do and perform each and every act and thing requisite and
necessary to be done in and about the premises, as fully to all intents and
purposes as the undersigned might or could do in person, hereby ratifying and
confirming all that said attorney-in-fact and agent, or his substitute or
substitutes, may lawfully do or cause to be done by virtue hereof.




IN
WITNESS WHEREOF, the undersigned has executed this Power of Attorney this 14th
day of March, 2008.




/s/ CRAIG
SAXTON


----------------------------


Craig
Saxton




EXHIBIT
24.1




POWER
OF ATTORNEY




KNOW ALL
YE PERSONS BY THESE PRESENTS, that the undersigned does hereby make, constitute
and appoint Stephen R. Davis and Thomas Pitler, each his attorney-in-fact and
agent with full power of substitution and resubstitution for him and in his
name, place and stead, in any and all capacities, to execute for him and on his
behalf an Annual Report pursuant to Section 13 of the Securities and Exchange
Act of 1934, as amended, on Form 10-K relating to the fiscal year ended December
31, 2007, of Neurogen Corporation (the "Company"), and any and all amendments to
the foregoing Annual Report on Form 10-K, which amendments may make such changes
in the Annual Report on Form 10-K as such attorney-in-fact deems appropriate,
and any other documents and instruments incidental thereto, and to file the
same, with all exhibits thereto and all documents in connection therewith, with
the Securities and Exchange Commission and the National Association of
Securities Dealers, Inc., granting unto said attorney-in-fact and agent, full
power and authority to do and perform each and every act and thing requisite and
necessary to be done in and about the premises, as fully to all intents and
purposes as the undersigned might or could do in person, hereby ratifying and
confirming all that said attorney-in-fact and agent, or his substitute or
substitutes, may lawfully do or cause to be done by virtue hereof.




IN
WITNESS WHEREOF, the undersigned has executed this Power of Attorney this 14th
day of March, 2008.




/s/ JOHN
SIMON


----------------------------


John
Simon