10/12/12 Page of 

INITIAL REVIEW EXPOSURE REPORT (IRExR) 

 Chemical ID: P-12-0566 Reviewer: Wong/AG 

 

 

Results Table: Dose, Concentration, and Days Exceeded Results Summary 

Exposure 

Scenario1 

 Water Landfill Stack Air Fugitive Air 

Drinking Water Fish Ingestion 

ADR LADD ADR LADD 7Q104 

CC = 3 

PDM 

Days 

Exceede

d 

LADD ADR LADD ADR LADD 

Release 

activity(ies)2

; exposure 

calculation(s)

3 

mg/kg/day mg/kg/day mg/kg/day mg/kg/day μg/l # Days mg/kg/day mg/kg/day mg/kg/day mg/kg/day mg/kg/day

PROC1: Max 

ADR: max 

acute eco 

1.16E05 --- 7 .78E-07 --- 2.30E-01 --- --- --- --- --- --- 

PROC1: 

PDM1 

--- --- --- --- 2.30E-01 --- --- --- --- --- 

PROC1: Max 

LADD 

--- 9 .51E-08 --- 3.96E-09 --- --- --- --- --- --- --- 

PROC2: Max 

ADR: max 

acute eco 

2.79E04 --- 1 .02E-05 --- 6.10E+00 --- --- --- --- --- --- 

PROC2: 

PDM1 

--- --- --- --- 2.50E-01 --- --- --- --- --- 

PROC2: Max 

LADD 

--- 1 .11E-07 --- 4.64E-09 --- --- --- --- --- --- --- 

1 Exposure scenario titles consist of release activity followed by exposure calculation abbreviation. 

2 Release activities are from engineering report's Manufacturing (Mfg), Processing (Proc) and Use release 

activity labels. Multiple release activities are combined in one exposure scenario if their releases occur at 

same location. 

3 Exposure calculations are Acute Dose Rate (ADR), Lifetime Average Daily Dose (LADD), and 

Probabilistic Dilution Model (PDM). There may be one, two, or all three exposure calculations per exposure 

scenario. CC is the aquatic concentration of concern. 

4 This column displays concentration values for the 7Q10 streamflow, which is defined as the average daily 

streamflow of the seven consecutive days of lowest flow within a ten year period. 

Remarks: 
10/12/12 Page of 

Results Table: Consumer Exposure Results Summary 

 Water (DtD) Dermal Inhalation 

Drinking Water Fish Ingestion 

ADR LADD ADR LADD 7Q10 PDM 

Days 

Exceed

ed 

ADR LADD ADR LADD 

Scenario mg/kg/day mg/kg/day mg/kg/day mg/kg/day μg/l # Days mg/kg/day mg/kg/day mg/kg/day mg/kg/day 

CEM2, 

General 

Purpose 

--- --- --- --- --- --- 5.44E-04 3.40E-04 1.72E-04 1.38E-03 

CEM2, 

Laundry 

detergen

t 

--- --- --- --- --- --- 1.73E-04 1.87E-05 2.79E-05 4.65E-06 

1 Down-the-Drain Module within NCEM2 model. 

2 Consumer Exposure Module within NCEM2 model.
10/12/12 Page of 

 INITIAL REVIEW EXPOSURE REPORT 

Chemical ID: P-12-0566 Assessor: Wong/AG 

ENVIRONMENTAL RELEASES 

 Scenario#:1 Number of Release Sites: 

 Release Activity: PROC1: Max ADR 

 Release Description: WATER LANDFILL 

Non-sludge/Sludge 

STACK FUGITIVE 

Total Releases: 

 (kg/yr) (kg/yr) (kg/yr) (kg/yr) 

 

 Non-sludge/Sludge 

Release Days/yr: 

Per Site Release: 

 (kg/site/day) (kg/site/day) (kg/site/day) (kg/site/day) 

Remarks: 
10/12/12 Page of 

INITIAL REVIEW EXPOSURE REPORT 

 Chemical ID: P-12-0566 

SITE-SPECIFIC HUMAN AND AQUATIC EXPOSURES TO SURFACE WATER RELEASES 

SCENARIO NUMBER:1 RELEASE ACTIVITY: PROC1: Max ADR 

FACILITY NAME: 

FACILITY LOCATION: 

RECEIVING WATER NAME: 

REACH NUMBER: FACILITY ON REACH: DISCHARGE TYPE: 

NPDES PERMIT #: EXPOSED POPULATION: Adult 

WWT 

REMOVAL 

(%) 

RELEASE 

DAYS 

PRETREATMENT 

RELEASE 

(kg/site/day) 

POSTTREATMENT 

RELEASE 

(kg/site/day) 

DWT 

(%) BCF 

(L/kg) 

 0.00 9.73 

AQUATIC EXPOSURE ESTIMATES - SURFACE WATER 

FLOW DESCRIPTOR Harmonic Mean 30Q5 7Q10 1Q10 PLANT 

FLOW (MLD) 

CONCENTRATION (μg/L) 4.45E-02 0.14 0.23 0.28 NA 

DRINKING WATER INGESTION AND FISH INGESTION EXPOSURE ESTIMATES 

Exposure Units 

Drinking Water 

Results 

Drinking Water 

Units 

Fish Ingestion 

Results 

Fish Ingestion 

Units 

Cancer 

LADDpot 9.51E-08 mg/kg/day 3.96E-09 mg/kg/day 

LADCpot 4.88E-06 mg/L 4.74E-05 mg/kg 

Acute 

ADRpot 1.16E-05 mg/kg/day 7.78E-07 mg/kg/day 

Surface Water Comments: 
10/12/12 Page of 

 INITIAL REVIEW EXPOSURE REPORT 

Chemical ID: P-12-0566 Assessor: Wong/AG 

ENVIRONMENTAL RELEASES 

 Scenario#:2 Number of Release Sites: 

 Release Activity: PROC1: PDM1 

 Release Description: WATER LANDFILL 

Non-sludge/Sludge 

STACK FUGITIVE 

Total Releases: 

 (kg/yr) (kg/yr) (kg/yr) (kg/yr) 

 

 Non-sludge/Sludge 

Release Days/yr: 

Per Site Release: 

 (kg/site/day) (kg/site/day) (kg/site/day) (kg/site/day) 

Remarks: 
10/12/12 Page of 

INITIAL REVIEW EXPOSURE REPORT 

 Chemical ID: P-12-0566 

SITE-SPECIFIC HUMAN AND AQUATIC EXPOSURES TO SURFACE WATER RELEASES 

SCENARIO NUMBER:2 RELEASE ACTIVITY: PROC1: PDM1 

FACILITY NAME: 

FACILITY LOCATION: 

RECEIVING WATER NAME: 

REACH NUMBER: FACILITY ON REACH: DISCHARGE TYPE: 

NPDES PERMIT #: EXPOSED POPULATION: Adult 

WWT 

REMOVAL 

(%) 

RELEASE 

DAYS 

PRETREATMENT 

RELEASE 

(kg/site/day) 

POSTTREATMENT 

RELEASE 

(kg/site/day) 

DWT 

(%) BCF 

(L/kg) 

 0.00 9.73 

AQUATIC EXPOSURE ESTIMATES - SURFACE WATER 

FLOW DESCRIPTOR Harmonic Mean 30Q5 7Q10 1Q10 PLANT 

FLOW (MLD) 

CONCENTRATION (μg/L) 4.45E-02 0.14 0.23 0.28 NA 

DRINKING WATER INGESTION AND FISH INGESTION EXPOSURE ESTIMATES 

Exposure Units 

Drinking Water 

Results 

Drinking Water 

Units 

Fish Ingestion 

Results 

Fish Ingestion 

Units 

Cancer 

LADDpot 9.51E-08 mg/kg/day 3.96E-09 mg/kg/day 

LADCpot 4.88E-06 mg/L 4.74E-05 mg/kg 

Acute 

ADRpot 1.16E-05 mg/kg/day 7.78E-07 mg/kg/day 

Surface Water Comments: 
10/12/12 Page of 

INITIAL REVIEW EXPOSURE REPORT 

 Chemical ID: P-12-0566 

SITE-SPECIFIC HUMAN AND AQUATIC EXPOSURES TO SURFACE WATER RELEASES 

SCENARIO NUMBER: 2 RELEASE ACTIVITY: PROC1: PDM1 

FACILITY NAME: 

FACILITY LOCATION: 

RECEIVING STREAM NAME: 

REACH NUMBER: FACILITY ON REACH: DISCHARGE TYPE: 

NPDES PERMIT NUMBER: GAGING STATION ID: 

GAGING STATION 

PERIOD OF RECORD:

GAGING STATION 

NUMBER OF 

OBSERVATIONS: 

NUMBER OF STATIONS ON 

REACH: 

MEAN FLOW (MLD): 7q10 FLOW (MLD): EFFLUENT FLOW (MLD)

 

RESULTS 

COC (μg/L) 

Percent of Year 

COC Exceeded 

Number of Days 

COC Exceeded 

Release 

days/year 

Pre-treatment 

Loading 

(kg/site/day) 

Waste Water 

Treatment (%) 

3.00 
10/12/12 Page of 

 INITIAL REVIEW EXPOSURE REPORT 

Chemical ID: P-12-0566 Assessor: Wong/AG 

ENVIRONMENTAL RELEASES 

 Scenario#:3 Number of Release Sites: 

 Release Activity: PROC1: Max LADD 

 Release Description: WATER LANDFILL 

Non-sludge/Sludge 

STACK FUGITIVE 

Total Releases: 

 (kg/yr) (kg/yr) (kg/yr) (kg/yr) 

 

 Non-sludge/Sludge 

Release Days/yr: 

Per Site Release: 

 (kg/site/day) (kg/site/day) (kg/site/day) (kg/site/day) 

Remarks: 
10/12/12 Page of 

INITIAL REVIEW EXPOSURE REPORT 

 Chemical ID: P-12-0566 

SITE-SPECIFIC HUMAN AND AQUATIC EXPOSURES TO SURFACE WATER RELEASES 

SCENARIO NUMBER:3 RELEASE ACTIVITY: PROC1: Max LADD 

FACILITY NAME: 

FACILITY LOCATION: 

RECEIVING WATER NAME: 

REACH NUMBER: FACILITY ON REACH: DISCHARGE TYPE: 

NPDES PERMIT #: EXPOSED POPULATION: Adult 

WWT 

REMOVAL 

(%) 

RELEASE 

DAYS 

PRETREATMENT 

RELEASE 

(kg/site/day) 

POSTTREATMENT 

RELEASE 

(kg/site/day) 

DWT 

(%) BCF 

(L/kg) 

 0.00 9.73 

AQUATIC EXPOSURE ESTIMATES - SURFACE WATER 

FLOW DESCRIPTOR Harmonic Mean 30Q5 7Q10 1Q10 PLANT 

FLOW (MLD) 

CONCENTRATION (μg/L) N/A N/A N/A N/A NA 

DRINKING WATER INGESTION AND FISH INGESTION EXPOSURE ESTIMATES 

Exposure Units 

Drinking Water 

Results 

Drinking Water 

Units 

Fish Ingestion 

Results 

Fish Ingestion 

Units 

Cancer 

LADDpot 9.51E-08 mg/kg/day 3.96E-09 mg/kg/day 

LADCpot 4.88E-06 mg/L 4.74E-05 mg/kg 

Acute 

ADRpot N/A mg/kg/day N/A mg/kg/day 

Surface Water Comments: 
10/12/12 Page of 

 INITIAL REVIEW EXPOSURE REPORT 

Chemical ID: P-12-0566 Assessor: Wong/AG 

ENVIRONMENTAL RELEASES 

 Scenario#:4 Number of Release Sites: 

 Release Activity: PROC2: Max ADR 

 Release Description: WATER LANDFILL 

Non-sludge/Sludge 

STACK FUGITIVE 

Total Releases: 

 (kg/yr) (kg/yr) (kg/yr) (kg/yr) 

 

 Non-sludge/Sludge 

Release Days/yr: 

Per Site Release: 

 (kg/site/day) (kg/site/day) (kg/site/day) (kg/site/day) 

Remarks: 
10/12/12 Page of 

INITIAL REVIEW EXPOSURE REPORT 

 Chemical ID: P-12-0566 

SIC-CODE BASED HUMAN AND AQUATIC EXPOSURES TO SURFACE WATER RELEASES 

SCENARIO #: 4 Number of Sites: RELEASE ACTIVITY:PROC2: 

Max ADR 

SIC-CODE DESCRIPTION: POTW's (All facilities) 

SIC-CODE (S): 4952 EXPOSED POPULATION: Adult 

WWT 

REMOVAL 

(%) 

RELEASE 

DAYS 

PRETREATMENT 

RELEASE 

(kg/site/day) 

POSTTREATMENT 

RELEASE 

(kg/site/day) 

DWT 

(%) BCF 

(L/kg) 

 0.00 9.73 

AQUATIC EXPOSURE ESTIMATES - SURFACE WATER 

PLANT 

TYPE 

% ILE 

FACILITY 

STREAM FLOW (MLD) STREAM CONC. (μg/l) 

Harmonic 

Mean 30Q5 7Q10 1Q10 

Harmonic 

Mean 30Q5 7Q10 1Q10 

ALL 50 125.56 44.02 26.80 22.53 5.15E-02 0.15 0.24 0.29 

ALL 10 11.11 1.94 1.06 0.96 0.58 3.34 6.10 6.74 

DRINKING WATER AND FISH INGESTION EXPOSURE ESTIMATES 

Exposure Units 

Drinking Water Results Drinking 

Water Units Fish Ingestion Results 

Fish 

Ingestion 

Units 

50% 10% 50% 10% 

Cancer 

LADDpot 5.51E-09 6.22E-08 mg/kg/day 2.30E-10 2.59E-09 mg/kg/day 

LADCpot 2.82E-07 3.19E-06 mg/L 2.75E-06 3.10E-05 mg/kg 

Acute 

ADRpot 1.23E-05 2.79E-04 mg/kg/day 9.01E-07 1.02E-05 mg/kg/day 

SIC Code Comments: 
10/12/12 Page of 

 INITIAL REVIEW EXPOSURE REPORT 

Chemical ID: P-12-0566 Assessor: Wong/AG 

ENVIRONMENTAL RELEASES 

 Scenario#:5 Number of Release Sites: 

 Release Activity: PROC2: PDM1 

 Release Description: WATER LANDFILL 

Non-sludge/Sludge 

STACK FUGITIVE 

Total Releases: 

 (kg/yr) (kg/yr) (kg/yr) (kg/yr) 

 

 Non-sludge/Sludge 

Release Days/yr: 

Per Site Release: 

 (kg/site/day) (kg/site/day) (kg/site/day) (kg/site/day) 

Remarks: 
10/12/12 Page of 

INITIAL REVIEW EXPOSURE REPORT 

 Chemical ID: P-12-0566 

SIC-CODE BASED HUMAN AND AQUATIC EXPOSURES TO SURFACE WATER RELEASES 

SCENARIO #: 5 Number of Sites: RELEASE ACTIVITY:PROC2: 

PDM1 

SIC-CODE DESCRIPTION: POTW's (All facilities) 

SIC-CODE (S): 4952 EXPOSED POPULATION: Adult 

WWT 

REMOVAL 

(%) 

RELEASE 

DAYS 

PRETREATMENT 

RELEASE 

(kg/site/day) 

POSTTREATMENT 

RELEASE 

(kg/site/day) 

DWT 

(%) BCF 

(L/kg) 

 0.00 9.73 

AQUATIC EXPOSURE ESTIMATES - SURFACE WATER 

PLANT 

TYPE 

% ILE 

FACILITY 

STREAM FLOW (MLD) STREAM CONC. (μg/l) 

Harmonic 

Mean 30Q5 7Q10 1Q10 

Harmonic 

Mean 30Q5 7Q10 1Q10 

ALL 50 125.56 44.02 26.80 22.53 2.13E-03 6.09E-03 1.00E-02 1.19E-02

ALL 10 11.11 1.94 1.06 0.96 2.41E-02 0.14 0.25 0.28 

DRINKING WATER AND FISH INGESTION EXPOSURE ESTIMATES 

Exposure Units 

Drinking Water Results Drinking 

Water Units Fish Ingestion Results 

Fish 

Ingestion 

Units 

50% 10% 50% 10% 

Cancer 

LADDpot 4.56E-09 5.15E-08 mg/kg/day 1.90E-10 2.15E-09 mg/kg/day 

LADCpot 2.34E-07 2.64E-06 mg/L 2.28E-06 2.57E-05 mg/kg 

Acute 

ADRpot 5.09E-07 1.15E-05 mg/kg/day 3.73E-08 4.22E-07 mg/kg/day 

SIC Code Comments: 
10/12/12 Page of 

INITIAL REVIEW EXPOSURE REPORT 

 Chemical ID: P-12-0566 

SIC CODE EXPOSURES TO SURFACE WATER RELEASES 

SCENARIO #: 5 RELEASE ACTIVITY: PROC2: PDM1 

SIC CODE DESCRIPTION: POTW's (All facilities) 

ASSOCIATED SIC CODES: 4952 

SIC CODE RESULTS 

COC (μg/L) 

Percent of 

Year COC 

Exceeded 

Number of 

Days COC 

Exceeded 

Release 

days/year 

Loading 

(kg/site/day) 

Waste Water 

Treatment (%) 

High/Avg 

Analysis 

3.00 High 
10/12/12 Page of 

 INITIAL REVIEW EXPOSURE REPORT 

Chemical ID: P-12-0566 Assessor: Wong/AG 

ENVIRONMENTAL RELEASES 

 Scenario#:6 Number of Release Sites: 

 Release Activity: PROC2: Max LADD 

 Release Description: WATER LANDFILL 

Non-sludge/Sludge 

STACK FUGITIVE 

Total Releases: 

 (kg/yr) (kg/yr) (kg/yr) (kg/yr) 

 

 Non-sludge/Sludge 

Release Days/yr: 

Per Site Release: 

 (kg/site/day) (kg/site/day) (kg/site/day) (kg/site/day) 

Remarks: 
10/12/12 Page of 

INITIAL REVIEW EXPOSURE REPORT 

 Chemical ID: P-12-0566 

SIC-CODE BASED HUMAN AND AQUATIC EXPOSURES TO SURFACE WATER RELEASES 

SCENARIO #: 6 Number of Sites: RELEASE ACTIVITY:PROC2: 

Max LADD 

SIC-CODE DESCRIPTION: POTW's (All facilities) 

SIC-CODE (S): 4952 EXPOSED POPULATION: Adult 

WWT 

REMOVAL 

(%) 

RELEASE 

DAYS 

PRETREATMENT 

RELEASE 

(kg/site/day) 

POSTTREATMENT 

RELEASE 

(kg/site/day) 

DWT 

(%) BCF 

(L/kg) 

 0.00 9.73 

AQUATIC EXPOSURE ESTIMATES - SURFACE WATER 

PLANT 

TYPE 

% ILE 

FACILITY 

STREAM FLOW (MLD) STREAM CONC. (μg/l) 

Harmonic 

Mean 30Q5 7Q10 1Q10 

Harmonic 

Mean 30Q5 7Q10 1Q10 

ALL 50 125.56 44.02 26.80 22.53 N/A N/A N/A N/A 

ALL 10 11.11 1.94 1.06 0.96 N/A N/A N/A N/A 

DRINKING WATER AND FISH INGESTION EXPOSURE ESTIMATES 

Exposure Units 

Drinking Water Results Drinking 

Water Units Fish Ingestion Results 

Fish 

Ingestion 

Units 

50% 10% 50% 10% 

Cancer 

LADDpot 9.84E-09 1.11E-07 mg/kg/day 4.10E-10 4.64E-09 mg/kg/day 

LADCpot 5.04E-07 5.70E-06 mg/L 4.91E-06 5.55E-05 mg/kg 

Acute 

ADRpot N/A N/A mg/kg/day N/A N/A mg/kg/day 

SIC Code Comments: 
10/12/12 Page of 

CEM Inputs ID Number: P-12-0566,7 

Product: unknown Chemical Name: P-12-0566 

Scenario: General Purpose Cleaner Population: Adult 

Molecular Weight (g/mole): 162 Vapor Pressure (torr) 0.00041 

Consumer Product Weight Fraction - 

Central Tendency (unitless): 

0.001 Consumer Product Weight Fraction - HighEnd (unitless): 0.001 

Inhalation Inputs 

Frequency of Use (chronic) (events/yr): 300 Exposure Duration (chronic) (years): 57 

Frequency of Use (acute) (events/day): 1 Exposure Duration (acute) (days): 1 

Mass of Product Used per Event - Central 

Tendency (g): 

61.5 Mass of Product Used per Event - High-End 

(g): 

123 

Inhalation Rate During Use (m3/hr): 1.1 Duration of Event - Central Tendency 

(hours/event): 

0.667 

Inhalation Rate After Use (m3/hr): 0.55 Duration of Event - High-End 

(hours/event): 

1.42 

Zone 1 Volume (m3): 20 Whole House Volume (m3): 369 

Air Exchange Rate (air exchanges/hr): 0.45 Body Weight (kg): 71.8 

 

Activity Patterns (Note: 1=Bedroom 2= Kitchen 3=Bathroom 4=Living Room 

 5=Utility Room 6=Car 7=Out) 

User: 1 1 1 1 1 1 1 2 2 1 5 4 2 4 6 7 4 2 2 7 4 4 4 1 

Non-User: 1 1 1 1 1 1 1 1 3 2 4 4 2 4 7 7 4 2 2 7 4 4 4 1 

Hour: 0 6 12 18 

Start Time: 7 Room of Use: 2. Kitchen 

Dermal Inputs 

Frequency of Use (chronic) (events/yr): 300 SA/BW (cm2/kg): 15.6 

Frequency of Use (acute) (events/day): 1 

 Exposure Duration (chronic) (years): 57 

Amount Retained / Absorbed to Skin 

(g/cm2-event): 

3.49e-05 Exposure Duration (acute) (days): 1 

 

 
10/12/12 Page of 

 

Averaging Time (chronic) (days): 2.74e+04 Averaging Time (acute) (days) : 1 

 

 
10/12/12 Page of 

CEM Inhalation Exposure Estimates 

 ID Number: P-12-0566,7 

 Scenario: General Purpose Cleaner Population: Adult 

 Exposure Duration (years) chronic: 57 Exposure Duration (days) acute: 1 

 

Exposure Units Result AT (days) 

 Chronic Cancer 

 LADDpot (mg/kg-day) 1.38e-03 2.74e+04 

 LADCpot (mg/m3) 7.47e-03 2.74e+04 

 Acute 

 ADRpot (mg/kg-day) 1.72e-04 1 

 Cppot (mg/m3) 2.30e-03 NA 

 LADD - Lifetime Average Daily Dose (mg/kg-day) LADC - Lifetime Average Daily Concentration (mg/m3) 

 ADR - Acute Dose Rate (mg/kg-day) Cp - Peak Concentration (mg/m3) 

 

Note: 75 years = 2.738e+04 days pot - potential dose 

Note: The general Agency guidance for assessing short-term, infrequent events (for most chemicals, an exposure of less than 24 

hours that occurs no more frequently than monthly) is to treat such events as independent, acute exposures rather than 

as chronic exposure. (Methods for Exposure-Response Analysis for Acute Inhalation Exposure to Chemicals (External 

Review Draft). EPA/600/R-98/051. April 1998)
10/12/12 Page of 

CEM Dermal Exposure Estimates 

 ID Number: P-12-0566,7 

 Scenario: General Purpose Cleaner Population: Adult 

 Exposure Duration (chronic) (years): 57 Exposure Duration (acute) (days): 1 

 

Exposure Units Result AT (days) 

Chronic Cancer 

 LADDpot (mg/kg-day) 3.40e-04 2.74e+04 

Acute 

 ADRpot (mg/kg-day) 5.44e-04 1 

 LADD - Lifetime Average Daily Dose (mg/kg-day) 

 ADR - Acute Dose Rate (mg/kg-day) 

 
10/12/12 Page of 

CEM Inputs ID Number: P-12-0566,8 

Product: unknown Chemical Name: P-12-0566 

Scenario: Laundry Detergent Population: Adult 

Molecular Weight (g/mole): 162 Vapor Pressure (torr) 0.00041 

Consumer Product Weight Fraction - 

Central Tendency (unitless): 

0.001 Consumer Product Weight Fraction - HighEnd (unitless): 0.001 

Inhalation Inputs 

Frequency of Use (chronic) (events/yr): 312 Exposure Duration (chronic) (years): 57 

Frequency of Use (acute) (events/day): 1 Exposure Duration (acute) (days): 1 

Mass of Product Used per Event - Central 

Tendency (g): 

200 Mass of Product Used per Event - High-End 

(g): 

400 

Inhalation Rate During Use (m3/hr): 1.1 Duration of Event - Central Tendency 

(hours/event): 

0.333 

Inhalation Rate After Use (m3/hr): 0.55 Duration of Event - High-End 

(hours/event): 

0.667 

Zone 1 Volume (m3): 20 Whole House Volume (m3): 369 

Air Exchange Rate (air exchanges/hr): 0.45 Body Weight (kg): 71.8 

 

Activity Patterns (Note: 1=Bedroom 2= Kitchen 3=Bathroom 4=Living Room 

 5=Utility Room 6=Car 7=Out) 

User: 1 1 1 1 1 1 1 2 3 5 5 4 2 4 6 7 4 2 2 7 4 4 4 1 

Non-User: 1 1 1 1 1 1 1 1 3 2 4 4 2 4 7 7 4 2 2 7 4 4 4 1 

Hour: 0 6 12 18 

Start Time: 9 Room of Use: 5. Utility Room 

Dermal Inputs 

Frequency of Use (chronic) (events/yr): 52 SA/BW (cm2/kg): 15.6 

Frequency of Use (acute) (events/day): 1 

 Exposure Duration (chronic) (years): 57 

Amount Retained / Absorbed to Skin 

(g/cm2-event): 

1.11e-05 Exposure Duration (acute) (days): 1 

 

 

 
10/12/12 Page of 

Averaging Time (chronic) (days): 2.74e+04 Averaging Time (acute) (days) : 1 

 

 
10/12/12 Page of 

CEM Inhalation Exposure Estimates 

 ID Number: P-12-0566,8 

 Scenario: Laundry Detergent (Machine Washing) Population: Adult 

 Exposure Duration (years) chronic: 57 Exposure Duration (days) acute: 1 

 

Exposure Units Result AT (days) 

 Chronic Cancer 

 LADDpot (mg/kg-day) 4.65e-06 2.74e+04 

 LADCpot (mg/m3) 1.45e-05 2.74e+04 

 Acute 

 ADRpot (mg/kg-day) 2.79e-05 1 

 Cppot (mg/m3) 2.29e-03 NA 

 LADD - Lifetime Average Daily Dose (mg/kg-day) LADC - Lifetime Average Daily Concentration (mg/m3) 

 ADR - Acute Dose Rate (mg/kg-day) Cp - Peak Concentration (mg/m3) 

 

Note: 75 years = 2.738e+04 days pot - potential dose 

Note: The general Agency guidance for assessing short-term, infrequent events (for most chemicals, an exposure of less than 24 

hours that occurs no more frequently than monthly) is to treat such events as independent, acute exposures rather than 

as chronic exposure. (Methods for Exposure-Response Analysis for Acute Inhalation Exposure to Chemicals (External 

Review Draft). EPA/600/R-98/051. April 1998)
10/12/12 Page of 

CEM Dermal Exposure Estimates 

 ID Number: P-12-0566,8 

 Scenario: Laundry Detergent (Hand 

Washing) 

 Population: Adult 

 Exposure Duration (chronic) (years): 57 Exposure Duration (acute) (days): 1 

 

Exposure Units Result AT (days) 

Chronic Cancer 

 LADDpot (mg/kg-day) 1.87e-05 2.74e+04 

Acute 

 ADRpot (mg/kg-day) 1.73e-04 1 

 LADD - Lifetime Average Daily Dose (mg/kg-day) 

 ADR - Acute Dose Rate (mg/kg-day)