INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form. Use additional sheet(s) if necessary.

1. Company Name and Address4. EPA ProductRegistration

United States Environmental Protection

Agency Washington, D.C. 20460

DATA CALL-IN RESPONSE

3. Date and Type of DCI 

GENERIC13-May-2010ID # GDCI-09990

2. Case # and Name

2475 OcthilinoneChemical # and Name 099901

Octhilinone

5. I wish to cancel this product registration voluntarily

6. Generic Data 7. Product Specific Data

7a. My product is an MUP andI agree to satisfy the MUP requirements on the attached form entitled "Requirements Status and Registrant's Response."

6a. I am claiming a GenericData Exemption because I obtain the active ingredient from the source EPA registration number listed below.

6b. I agree to satisfy Generic Data requirements as indicated on the attached form entitled "Requirements Status and Registrant's Response."

N.A. N.A. N.A. 

10. Name of Company 11. Phone Numb

9. Date 8. Certification I certify that the statements made on this form and all attachments are true, accurate, and complete. I acknowledge that any knowingly false or misleading statement may be punishable by fine, imprisonment or both under applicable law.

Signature and Title of Company's Authorized Representative__________________________________
Octhilinone

INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form. Use additional sheet(s) if necessary.

4. Guideline Requirement Number

5. Study Title

1. Company Name and Address

United States Environmental Protection

Agency Washington, D.C. 20460

REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE

3. Date and Type of DC

ID #GENERIC13-May-2010

GDCI-09990

2. Case # and Name

2475 Octhilinone

Chemical # and Name 099901

7. Test Substance

6. Use Pattern

P

R

O

T

O

C

O

L

Progress

Reports

1 2 3

Applicator Exposure Data Requirements (Antimicrobial)

875.1100 Dermal exposure--outdoor (29 ,30 ,31) BB, Y, X, Z 875.1200 Dermal exposure--Indoor (15 ,16 ,17) BB, Y, X, Z 875.1300 Inhalation exposure--outdoor (12 ,13 ,14) BB, Y, X, Z 

(18 ,19 ,20,21)

875.1400 Inhalation exposure--indoor BB, Y, X, Z 875.1600 Application exposure monitoring data reporting (1 ,22) BB, Y, X, Z 875.1700 Product Use Information (28) BB, Y, X, Z 

Post-Application Exposure Data Requirements (ConventionalChemical)

(24 ,25 ,26,27)

875.2500 Inhalation exposure BB, Y, X, Z 

Postapplication Exposure Data Requirements (Antimicrobial)

875.2800 Description of human activity (23) BB, Y, X, Z 875.2300 Indoor surface residue dissipation (32 ,33 ,34) BB, Y, X, Z 

12. Name of Company 13. Phone NumbSignature and Title of Company's Authorized Representative__________________________________10. Certification I certify that the statements made on this form and all attachments are true, accurate, and complete. I acknowledge that any knowingly false or misleading statement may be punishable by fine, imprisonment or both under applicable law

11. Date
Octhilinone

INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form. Use additional sheet(s) if necessary.

4. Guideline Requirement Number

5. Study Title

1. Company Name and Address

United States Environmental Protection

Agency Washington, D.C. 20460

REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE

3. Date and Type of DC

ID #GENERIC13-May-2010

GDCI-09990

2. Case # and Name

2475 Octhilinone

Chemical # and Name 099901

7. Test Substance

6. Use Pattern

P

R

O

T

O

C

O

L

Progress

Reports

1 2 3

875.2700 Product Use Information (35) BB, Y, X, Z 

Residue Chemistry Data Requirements (Antimicrobial)

860.1500 Crop field trials(HONEY) (36) BB, Y, X, Z TEP 860.1500 Crop field trials(HONEYCOMB) (37) BB, Y, X, Z TEP 

Toxicology Data Requirements (Antimicrobial)

870.3465 90-day inhalation toxicity (11) BB, Y, X, Z TGAI 850.3030 Honey bee toxicity of residues on foliage (4) BB, Y, X, Z 850.4225 Seedling emergence, Tier II (9) BB, Y, X, Z 850.4250 Vegetative vigor, Tier II (10) BB, Y, X, Z 850.5400 Algal toxicity, Tiers 1 and II (3 ,7 ,8) BB, Y, X, Z 870.3200 21/28-day dermal toxicity (5 ,6) BB, Y, X, Z 

Initial to indicate certification as to information on this page (fulltext of certification is on page one).

Date
Octhilinone

INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form. Use additional sheet(s) if necessary.

4. Guideline Requirement Number

5. Study Title

1. Company Name and Address

United States Environmental Protection

Agency Washington, D.C. 20460

REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE

3. Date and Type of DC

ID #GENERIC13-May-2010

GDCI-09990

2. Case # and Name

2475 Octhilinone

Chemical # and Name 099901

7. Test Substance

6. Use Pattern

P

R

O

T

O

C

O

L

Progress

Reports

1 2 3

SS-WoodLeach Wood leaching study (2) BB, Y, X, Z 

Initial to indicate certification as to information on this page (fulltext of certification is on page one).

Date
Case # and Name: 2475 Octhilinone

DCI Number: GDCI-099901-29707

Footnotes: [The following notes are referenced in column two (5. Study File) of the REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE form.]Key:

United States Environmental Protection

Agency Washington, D.C. 20460

FOOTNOTES AND KEY DEFINITIONS FOR GUIDELINE REQUIREMENTS

TEP = Typical End Use Product [TEP]; TGAI = Technical Grade Active Ingredient [TGAI]

Use Categories Key:

X - Y - Z - 

Materials preservativesIndustrial processes and water s

Industrial processes and water s

BB - Wood preservatives

1 This guideline is required for both dermal and inhalation exposure where applicable.2 Protocols must be submitted to the Agency for approval before initiating a study.3 Studies needed for 4 organisms: Freshwater Diatom, Marine Diatom, Blue-Green Cyanobacteria, and Freshwater Floating Macrophyte Duckweed.4 Data are required only when the formulation contains one or more active ingredients having an acute LD50 of <11 micrograms per bee as determined in 

the use pattern(s) indicate(s) that honey bees may be exposed to the pesticide.

5 Required for agricultural uses or if repeated human dermal exposure may occur. Not required if an acceptable 90?day dermal toxicity study is performed 

6 EP testing is required if the product, or any component of it, may increase dermal absorption of the active ingredient(s) as determined by testing using th

pharmacologic effects.

7 Not required for aquatic residential uses.8 Not required for known phytotoxicants.9 Please note that the OPPIN system for generating the Data Call-Ins has not incorporated changes made to 40 CFR Part 158 (revised as of July 1, 2009)

CFR Part 158 for this study titled "seedling emergence" replaced the guideline number 850.4225 4250 with guideline number 850.4100. However, the 8both) a Tier I or a Tier II study. For the purpose of this DCI, the study requested is for a Tier II study. For more information, see: 158.660 in the current 4

10 Please note that the OPPIN system for generating the Data Call-Ins has not incorporated changes made to 40 CFR Part 158 (revised as of July 1, 2009)

CFR Part 158 for this study titled "vegetative vigor" replaced the guideline number 850.4250 with guideline number 850.4150. However, the 850.4150 nor a Tier II study. For the purpose of this DCI, the study requested is for a Tier II study. For more information, see: 158.660 in the current 40 CFR.

11 Required if the active ingredient is a gas at room temperature or if the Agency determines that use of the product may result in repeated inhalation expos

regardless of whether the major route of exposure is inhalation.
Case # and Name: 2475 Octhilinone

DCI Number: GDCI-099901-29707

Footnotes: [The following notes are referenced in column two (5. Study File) of the REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE form.]Key:

United States Environmental Protection

Agency Washington, D.C. 20460

FOOTNOTES AND KEY DEFINITIONS FOR GUIDELINE REQUIREMENTS

TEP = Typical End Use Product [TEP]; TGAI = Technical Grade Active Ingredient [TGAI]

Use Categories Key:

X - Y - Z - 

Materials preservativesIndustrial processes and water s

Industrial processes and water s

BB - Wood preservatives

12 The Agency will require application exposure data beyond the required product use information (Guideline 875.1700) if at least one of the following expo

following toxicity criteria are met by the TEP, TGAI, or one of the pesticide's metabolites: (i) Exposure criteria. (A) Dermal exposure is likely to occur durto occur during use. (C) Adequate surrogate exposure data (e.g. PHED) to estimate the magnitude of exposure for a particular work activity with an acceunavailable. (ii) Toxicity criteria. (A) The acute dermal LD50 is less than or equal to 200 mg/kg (i.e., Toxicity Category I (Guideline 870.1200) as per 40 LC50 (Guideline 870.1300) is less than or equal to 0.05 mg/liter (i.e., 4-hour exposure, Toxicity Category I) and the TGAI has a vapor pressure greater thoutdoors or any indoor application regardless of the vapor pressure. (C) The pesticide is found to be a neurotoxicant (Guideline 870.6200). (D) The pesttoxicant (Guidelines 870.3700 and 870.6300). (E) The pesticide is found to be a carcinogen (Guideline 870.4200). (F) The pesticide shows potential adas 90-day oral (Guideline 870.3100), 21-day repeated dermal toxicity (Guideline 870.3200), 90-day dermal toxicity (Guideline 870.3250), 90-day inhalatand fertility effects (Guideline 870.3800), and chronic feeding (Guideline 870.4100). (G) The pesticide is found to be a mutagen (Guidelines 870.5100 to (Guideline 870.7800). (H) Epidemiological or poisoning incidence data indicate adverse effects from handling the pesticide.

13 Required for outdoor uses when that is the primary use or if outdoor uses are expected to result in greater exposure than indoor uses.14 Protocols must be submitted to the Agency for approval before initiating a study.15 The Agency will require application exposure data beyond the required product use information (Guideline 875.1700) if at least one of the following expo

following toxicity criteria are met by the TEP, TGAI, or one of the pesticide's metabolites: (i) Exposure criteria. (A) Dermal exposure is likely to occur durto occur during use. (C) Adequate surrogate exposure data (e.g. PHED) to estimate the magnitude of exposure for a particular work activity with an acceunavailable. (ii) Toxicity criteria. (A) The acute dermal LD50 is less than or equal to 200 mg/kg (i.e., Toxicity Category I (Guideline 870.1200) as per 40 LC50 (Guideline 870.1300) is less than or equal to 0.05 mg/liter (i.e., 4-hour exposure, Toxicity Category I) and the TGAI has a vapor pressure greater thoutdoors or any indoor application regardless of the vapor pressure. (C) The pesticide is found to be a neurotoxicant (Guideline 870.6200). (D) The pesttoxicant (Guidelines 870.3700 and 870.6300). (E) The pesticide is found to be a carcinogen (Guideline 870.4200). (F) The pesticide shows potential adas 90-day oral (Guideline 870.3100), 21-day repeated dermal toxicity (Guideline 870.3200), 90-day dermal toxicity (Guideline 870.3250), 90-day inhalatand fertility effects (Guideline 870.3800), and chronic feeding (Guideline 870.4100). (G) The pesticide is found to be a mutagen (Guidelines 870.5100 to (Guideline 870.7800). (H) Epidemiological or poisoning incidence data indicate adverse effects from handling the pesticide.

16 Protocols must be submitted to the Agency for approval before initiating a study.17 Required for indoor uses such as aquaria when the Agency determines such uses are likely to result in greater exposure than outdoor uses.
Case # and Name: 2475 Octhilinone

DCI Number: GDCI-099901-29707

Footnotes: [The following notes are referenced in column two (5. Study File) of the REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE form.]Key:

United States Environmental Protection

Agency Washington, D.C. 20460

FOOTNOTES AND KEY DEFINITIONS FOR GUIDELINE REQUIREMENTS

TEP = Typical End Use Product [TEP]; TGAI = Technical Grade Active Ingredient [TGAI]

Use Categories Key:

X - Y - Z - 

Materials preservativesIndustrial processes and water s

Industrial processes and water s

BB - Wood preservatives

18 The Agency will require application exposure data beyond the required product use information (Guideline 875.1700) if at least one of the following expo

following toxicity criteria are met by the TEP, TGAI, or one of the pesticide's metabolites: (i) Exposure criteria. (A) Dermal exposure is likely to occur durto occur during use. (C) Adequate surrogate exposure data (e.g. PHED) to estimate the magnitude of exposure for a particular work activity with an acceunavailable. (ii) Toxicity criteria. (A) The acute dermal LD50 is less than or equal to 200 mg/kg (i.e., Toxicity Category I (Guideline 870.1200) as per 40 LC50 (Guideline 870.1300) is less than or equal to 0.05 mg/liter (i.e., 4-hour exposure, Toxicity Category I) and the TGAI has a vapor pressure greater thoutdoors or any indoor application regardless of the vapor pressure. (C) The pesticide is found to be a neurotoxicant (Guideline 870.6200). (D) The pesttoxicant (Guidelines 870.3700 and 870.6300). (E) The pesticide is found to be a carcinogen (Guideline 870.4200). (F) The pesticide shows potential adas 90-day oral (Guideline 870.3100), 21-day repeated dermal toxicity (Guideline 870.3200), 90-day dermal toxicity (Guideline 870.3250), 90-day inhalatand fertility effects (Guideline 870.3800), and chronic feeding (Guideline 870.4100). (G) The pesticide is found to be a mutagen (Guidelines 870.5100 to (Guideline 870.7800). (H) Epidemiological or poisoning incidence data indicate adverse effects from handling the pesticide.

19 Required for outdoor uses when that is the primary use or if outdoor uses are expected to result in greater exposure than indoor uses.20 Protocols must be submitted to the Agency for approval before initiating a study.21 Required for indoor uses such as aquaria when the Agency determines such uses are likely to result in greater exposure than outdoor uses.22 Data reporting and calculations are required when exposure data are submitted.23 The required description of human activity data include data such as frequency and duration of exposure to evaluate the potential differences in exposur

and children), and to determine how specific postapplication activity patterns affect exposure levels.

24 The Agency will require postapplication exposure data beyond the required product use and human activity information by the appropriate route(s) of ex

exposure criteria and one of the following toxicity criteria are met by the TGAI or any of the pesticide's metabolites:(i) Exposure criteria. (A) Dermal expbystanders and residents, is likely to occur. (B) Inhalation exposure to workers upon reentry, or to bystanders and residents, is likely to occur. (C) The hpesticide use pattern (e.g. use in swimming pools and spas) can lead to potentially high exposures. (D) Surrogate exposure data that the Agency deemthe magnitude of exposure for a particular postapplication work activity, with an adequate degree of confidence, are unavailable.(ii) Toxicity criteria. (A) (Guideline 870.1200) is less than or equal to 2000 mg/kg (i.e., Toxicity Category I or II as per 40 CFR 156.10). (B) The acute inhalation LC50 of the TGAequal to 0.5 mg/liter (i.e., 4-hour exposure, Toxicity Category I or II) and the TGAI has a vapor pressure greater than 10-3 mm Hg at 25 degrees C if useregardless of the vapor pressure. (C) The acute oral LD50 of the TGAI (Guideline 870.1100) is less than 50 mg/kg (i.e., Toxicity Category I). (D) The pe(Guideline 870.6200). (E) The pesticide is found to be a developmental toxicant (Guidelines 870.3700 and 870.6300). (F) The pesticide is found to be a The pesticide shows potential adverse effects in subchronic studies such as the 90-day oral (Guideline 870.3100), 21-day repeated dose dermal toxicity toxicity (Guideline 870.3250), 90-day inhalation (Guideline 870.3465), reproduction a

25 Protocols must be submitted to the Agency for approval before initiating a study.
Case # and Name: 2475 Octhilinone

DCI Number: GDCI-099901-29707

Footnotes: [The following notes are referenced in column two (5. Study File) of the REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE form.]Key:

United States Environmental Protection

Agency Washington, D.C. 20460

FOOTNOTES AND KEY DEFINITIONS FOR GUIDELINE REQUIREMENTS

TEP = Typical End Use Product [TEP]; TGAI = Technical Grade Active Ingredient [TGAI]

Use Categories Key:

X - Y - Z - 

Materials preservativesIndustrial processes and water s

Industrial processes and water s

BB - Wood preservatives

26 For antifoulants, testing for postapplication exposure is required to evaluate exposure to persons removing antifoulants from treated surfaces, such as bo

OSHA regulations, and to evaluate bystander inhalation and dermal exposure following application of antifoulants.

27 In the aquatic areas use category, conditionally required for indoor aquaria or ornamental ponds only.28 Use information pertains to the methods of mixing, loading and applying the pesticide and associated work practices that will play an integral part in dete

pesticide handlers. Required product use information includes range and typical values for: Application rates; area treated per day and per year; timing aper year for private and professional handlers; exposure time per activity; types of handling equipment; type of clothing worn; geographical distribution of 

29 The Agency will require application exposure data beyond the required product use information (Guideline 875.1700) if at least one of the following expo

following toxicity criteria are met by the TEP, TGAI, or one of the pesticide's metabolites: (i) Exposure criteria. (A) Dermal exposure is likely to occur durto occur during use. (C) Adequate surrogate exposure data (e.g. PHED) to estimate the magnitude of exposure for a particular work activity with an acceunavailable. (ii) Toxicity criteria. (A) The acute dermal LD50 is less than or equal to 200 mg/kg (i.e., Toxicity Category I (Guideline 870.1200) as per 40 LC50 (Guideline 870.1300) is less than or equal to 0.05 mg/liter (i.e., 4-hour exposure, Toxicity Category I) and the TGAI has a vapor pressure greater thoutdoors or any indoor application regardless of the vapor pressure. (C) The pesticide is found to be a neurotoxicant (Guideline 870.6200). (D) The pesttoxicant (Guidelines 870.3700 and 870.6300). (E) The pesticide is found to be a carcinogen (Guideline 870.4200). (F) The pesticide shows potential adas 90-day oral (Guideline 870.3100), 21-day repeated dermal toxicity (Guideline 870.3200), 90-day dermal toxicity (Guideline 870.3250), 90-day inhalatand fertility effects (Guideline 870.3800), and chronic feeding (Guideline 870.4100). (G) The pesticide is found to be a mutagen (Guidelines 870.5100 to (Guideline 870.7800). (H) Epidemiological or poisoning incidence data indicate adverse effects from handling the pesticide.

30 Required for outdoor uses when that is the primary use or if outdoor uses are expected to result in greater exposure than indoor uses.31 Protocols must be submitted to the Agency for approval before initiating a study.32 The Agency will require postapplication exposure data beyond the required product use and human activity information by the appropriate route(s) of ex

exposure criteria and one of the following toxicity criteria are met by the TGAI or any of the pesticide's metabolites:(i) Exposure criteria. (A) Dermal expbystanders and residents, is likely to occur. (B) Inhalation exposure to workers upon reentry, or to bystanders and residents, is likely to occur. (C) The hpesticide use pattern (e.g. use in swimming pools and spas) can lead to potentially high exposures. (D) Surrogate exposure data that the Agency deemthe magnitude of exposure for a particular postapplication work activity, with an adequate degree of confidence, are unavailable.(ii) Toxicity criteria. (A) (Guideline 870.1200) is less than or equal to 2000 mg/kg (i.e., Toxicity Category I or II as per 40 CFR 156.10). (B) The acute inhalation LC50 of the TGAequal to 0.5 mg/liter (i.e., 4-hour exposure, Toxicity Category I or II) and the TGAI has a vapor pressure greater than 10-3 mm Hg at 25 degrees C if useregardless of the vapor pressure. (C) The acute oral LD50 of the TGAI (Guideline 870.1100) is less than 50 mg/kg (i.e., Toxicity Category I). (D) The pe(Guideline 870.6200). (E) The pesticide is found to be a developmental toxicant (Guidelines 870.3700 and 870.6300). (F) The pesticide is found to be a The pesticide shows potential adverse effects in subchronic studies such as the 90-day oral (Guideline 870.3100), 21-day repeated dose dermal toxicity toxicity (Guideline 870.3250), 90-day inhalation (Guideline 870.3465), reproduction a

33 Required if the use pattern and formulation types involve significant potential exposure to humans by evaporation of residues from surfaces or contact w
Case # and Name: 2475 Octhilinone

DCI Number: GDCI-099901-29707

Footnotes: [The following notes are referenced in column two (5. Study File) of the REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE form.]Key:

United States Environmental Protection

Agency Washington, D.C. 20460

FOOTNOTES AND KEY DEFINITIONS FOR GUIDELINE REQUIREMENTS

TEP = Typical End Use Product [TEP]; TGAI = Technical Grade Active Ingredient [TGAI]

34 Protocols must be submitted to the Agency for approval before initiating a study.35 Required product use information includes reapplication rates and frequencies, re-entry intervals, rinsing and other residue removal practices, and any o

application.

36 Data are required whenever a pesticide is to be used in a food handling or feed handling establishment unless theoretical calculations, radiolabeled labo

study, or other data show that residues will not occur in food.

37 Data are required whenever a pesticide is to be used in a food handling or feed handling establishment unless theoretical calculations, radiolabeled labo

study, or other data show that residues will not occur in food.
United States Environmental Protection

Agency Washington, D.C. 20460

LIST OF ALL REGISTRANTS SENT THIS DATA CALL-IN NOTICE

Co. Nr. Company Name Agent For Address City & S

Case # and Name: 2475,Octhilinone

6836 LONZA INC 90 BOROLINE ROAD ALLEND707 ROHM & HAAS CO 100 INDEPENDENCE MALL WEST PHILAD3090 SANITIZED INC PO Box 2211 57 NEW MILFORD TKPE. NEW PR67071 THOR GMBH THOR SPECIALTIES INC. 56 QUARRY ROAD TRUMB