# Environmental Fate and Ecological Risk Assessment for the Registration of the New Chemical Cyantraniliprole

- Amended

Cyantraniliprole

3

- bromo

- 1

- )3

- chloro

- 2

- pyridinyl)

- N

- [4

- cyanlo

- 2

- methyl

- 6

- [{methylamino)carbonyl]phenyl]

- 1H

- pyrazole

- 5

- carboxamide

CAS No. 736994

- 63

- 1

PC Code 090098

Prepared by:

Me ghan Radtke, Ph. D. , Biologist Christopher M. Koper
, M.S., Chemist U. S. Environmental Protection Agency Office of Pesticide Programs

Environmental Fate and Effects Division

Environmental Risk Branch I

1200 Pennsylvania Ave., NW

Mail Code 7507P Washington, DC 20460 

### Reviewed by: Stephen Wente, Ph.D., Biologist
Michael Lowit, Ph.D., Ec ologist N N

N N H

O Cl Br

N H O

N

### 2 TABLE OF CONTENTS

I. EXECUTIVE SUMMARY

................................ ................................ ........................ 10

A. Nature of Chemical Stressor

................................ ................................ .. 10

B. Conclusions

- Exposure Characterization

................................ ............ 10

C. Conclusions

- Effects Characterization

................................ ................. 11

D. Potential Risks to Non

- target Organisms

................................ ............. 11 E. Uncertainties and Data Gaps

................................ ................................ . 13

II PROBLEM FORMULATION

................................ ................................ ................. 13

A. Stressor Source and Distribution

................................ .......................... 14 1. Source and Intensity

................................ ................................ ... 14 2. Physical/Chemical/Fate and Transport Properties

.................. 15 3. Pesticide Type, Class, and Mode of Acti on

................................ . 9

4. Overview of Pesticide Usage

................................ ........................ 9 B. Receptors

................................ ................................ ................................ ... 9

1. Aquatic and Terrestrial Effects

................................ ................... 9 2. Ecosystems Potentially at Risk

................................ .................. 10

C. Assessment Endpoints

................................ ................................ ............ 10 D. Conceptual Model

................................ ................................ ................... 12

1. Risk Hypotheses

................................ ................................ .......... 12 2. Diagram

................................ ................................ ....................... 19 E. Analysis Plan

................................ ................................ ............................ 1 4 1. Preliminary Identification of Data Gaps and Methods

........... 15 2. Measures to Evaluate Risk Hypotheses and Conceptual Model

................................ ................................ ................................ ....... 15

a. Measures of Exposure

................................ ..................... 15

b. Measures of Effect

................................ .......................... 16

III. ANALYSIS

................................ ................................ ................................ .......... 17

A. Use Characterization

................................ ................................ .............. 17 B. Exposure Characterization

................................ ................................ ..... 26

1. Environmental Fate and Transport Characterization

............ 28

a. Degradation

................. ..................................................... 28

b. Mobility and Transport

....................................... 30

c. Field Studies

..................................................................... 30

d. Degradates ......................................................31

e. Total Toxic Residues (TTR) .................................31 2. Measures of Aquatic Exposure

................................ .................. 26

a. Aquatic Exposure Modeling

................................ .......... 26

b. Aquatic Exposure Monitoring and Field Data

............. 4 9 3. Measures of Terrestrial Exposure

................................ ............. 43

a. Terrestrial Exposure Modeling

................................ ..... 43 C. Ecological Effects Characterization

................................ ......................... 57 1. Aquatic Effects Ch aracterization

................................ .................. 57 a. Aquatic Animals

................................ ................................ .. 57

b. Aquatic Plants

................................ ................................ . 63

2. Terrestrial Effects Characterization

................................ ............. 65

### 3 a. Terrestrial Animals

................................ ............................. 65

b. Terrestrial Plants

................................ ............................ 86

IV. Risk Characterization

................................ ................................ .......................... 87

A. Risk Estimation

- Integration of Exposure and Effects Data

................. 87

1. Non

- target Aquatic Animals and Plants

................................ ....... 87

2. Non

- target Terrestrial Animals

................................ ................... 115

3. Non

- target Terrestrial and Semi

- aquatic Plants

........................ 121 B. Risk Description

................................ ................................ ....................... 124

1. Degradate Persistence and Accumulation

............................... 130

2 . Risks to Aquatic Organisms

................................ ...................... 130

a. Animals

................................ ................................ .......... 124

b. Plant s

................................ ................................ .............. 127

3 . Risks to Terrestrial Organisms

................................ ................. 128

a. Animals

................................ ................................ .......... 128

b. Plants

................................ ................................ .............. 141

4 . Review of Incident Data

................................ ............................... 142

5 . Federally Threatened and Endangered (Listed) Species Concerns

................................ ................................ ................................ ..... 142

a. Action Area

................................ ................................ ..... 142

b. Taxonomi c Groups Potentially at Risk

........................ 143 (1). Discussion of Risk Quotients

........................... 143 ( 2). Probit Dose Response Relationship

................ 143 (3). Spray Dr ift Analysis ................................14 9 (4 ). Indirect Effects Analysis

................................ ... 144 (5 ). Critical Habitat

................................ ................. 149 (6 ). Co

- oc currence Analysis

................................ .... 150

V. UNCERTAINTIES

................................ ................................ ................................ .. 152

V I . REFERENCES

................................ ................................ ................................ ....... 152 Appendix A Screening Inhibition Program

..................... ...................17 7 Appendix B Screening Tool for Inhalation Risk ..................................17 9 Appendix C Major and Minor Degradates.. .......................................1 8 1 Appendix D PRZM/EXAMS Output......

...................................... ... 188 Appendix E T

- REX Input and Output

... ..........................................18 9 Appendix F EEC Calculations for Soil

..... ................................ .........191 Appendix G TerrPlant Input and Output

......... ................................197 Appendix H Agency Levels of Concern (LOC)..... ...............................199 Appendix I LOCATES Endangered Species List

............................. ... 200

### 4 I. EXECUTIVE SUMMARY

A. Nature of Chemical Stressor

Cyantraniliprole is a new insecticide that is proposed for registration by the E. I

. D uPont de Nemours and Company (DuPont) and Syngenta Crop Protection (Syngenta) for agricultural and non

- agricultural uses. Proposed uses include: bushberries, citrus, cotton, oil seeds, pome fruit, stone fruit, tree nuts, vegetables (bulb, corm and tuberous, cucurbit, fruiting, leafy brassica, and leafy non

- brassica), and profe ssional products (fly bait,

indo or and outdoor insect control for public health pests such as cockroaches, ants, flies and termites, nuisance insect pests and turfgrass and ornamentals). In addition to technical cyan tranili prole, DuPont has proposed eight formulations for registration and Syngenta has proposed five. Three of the Syngenta products are co

- formulated with the

insecticide

, thiamethoxam. Cyantraniliprole would be app lied via foliar spray

, micro sprinkler chemigation, bark spray, drip chemi gation, soil drench, soil treatment, seed

treatmen t, seed piece treatment, or bait. Rates vary but do not exceed 0.69 lb ai/A as a seasonal maximum for agricultural uses and 0.5 lb ai/A for non

- agricultural uses.

Cyant raniliprole is a systemic, broad

- spectrum insecticide that belongs to the diamide class of chemistry. It translocates through plants via both the xylem and phloem. Cyantraniliprole b inds with insect ryanodine receptors, which causes muscle contractions that lead to paralysis and death. It is nearly identical to the insecticide

chlora n tran iliprole, except for the substitution of a cyano

- group instead of a chloro

group.

B. Conclusions

- Exposure Characterization

Cyantraniliprole is soluble at neutral pH and given its low vapor pressure and Henry’s Law constants, is not consider ed volatile and is not likely prone to atmospheric transport. While cyantraniliprole is subject to both abiotic (alkaline hydrolysis (t 1/2 

### = 21 hrs) and photodegradation in aqueous (t 1/2 

### = 8 hrs) and moist soil environments) and biotic (aerobic and anaero bic biotransformation in terrestrial and aquatic environments (t 1/2 

### range from 2 days to 3 months) degradation, the chemical degrades into a total of 13 degradation products. Of these degradates, eight are major and five are minor. Based on degradate aer obic soil metabolism and mobility studies, six of the eight major degradates

had longer dissipation half

- life ( DT 50 

### ) values (more persistent) and three of the eight degradates were more mobile than the parent cyantraniliprole. According to the Food

and Agriculture Organization ( FAO ) classification system

, based on organic carbon partitioning coefficients, cyantraniliprole is characterized as moderately mobile.

Bio concentration factor data (BCF value <1 in whole fish) indicate that cyantraniliprole

is no t likely to bioaccumulate

.

Given the uncertainty of the behavior and toxicity of these degradates, the ir toxicity is assumed to be equivalent to the parent compound, cyantraniliprole. For the aquatic exposure modeling, a total toxic residue approach (co nsiders the parent compound and

### 5 eight major degradates including two degradates from terrestrial field studies ) was utilized. For surface water, peak estimated environmental concentrations (EECs) ranged from 0.23 μg/L from cyantraniliprole use on trees us ing the Oregon Christmas tree

scenario to 3 8 μg/L from cyantraniliprole use on cotton using the North Carolina cotton scenario. For pore water, peak EECs ranged from 0.22 μg/L from cyantraniliprole use on trees using the Oregon Christmas tree scenario to 3 7 μg/L from cyantraniliprole use on rapeseed using the North Dakota wheat scenario.

Since cyantraniliprole is a new chemical, no monitoring data were found when searching

the U.S. Geological Survey National Water Quality Assessment ( USGS NAWQA )

surfa ce water and ground water database and California Department of Pesticide Regulation (CDPR) surface water database. Likewise, no monitoring data were found for the degradation products.

C. Conclusions

- Effects Characterization

Based on the available data, cyantraniliprole is classified as slightly to moderately toxic

to freshwater fish; slightly toxic to estuarine/marine fish; slightly to very highly toxic to freshwater invertebrates; moderately to highly toxic to estuarine/mari ne invertebrates, highly toxic to benthic invertebrates; highly to very highly toxic to terrestrial insects; and practically non

- toxic to mammals and birds on an acute exposure basis. No chronic effects or mortality were noted for freshwater fish (NOAEC = 10.7 mg ai/L) or benthic invertebrates ( overlaying water NOAEC = 10 μg ai/L). For estuarine/marine fish (NOAEC < 0.75 mg ai/L) and freshwater invertebrates (NOAEC = 6.56 μg ai/L), body length was the most sensitive endpoint. Chronic data were not availa ble for

estuarine/marine invertebrates. The reproductive studies for birds indicated no effects up to the maximum dietary level tested (NOAEC = 1000 mg ai/kg

- diet). The most sensitive NOAEC for mammalian endpoints was 20 mg ai/kg

- diet and was based on a decrease in thyroid weight. Offspring also showed decreases in organ weight and body weight , but at higher exposure levels (NOAEC = 200 mg ai/kg

- diet) . No reproductive endpoints were

affected. For terrestrial plants, the EC 25 

### value s were greater than 0.134 lb ai/A for both seedling emergence and vegetative vigor tests. The NOAEC followed a similar pattern (= 0.134 lb ai/A), except for the monocot vegetative vigor NOAEC

, which was 0.067 lb

ai/A. The most sensitive non

- vascular aquat ic plant tested was the green algae ( Pseudokirchneriella subcapitata ) with a non

- definitive EC 50 

### >1 0 mg ai /L and a NOAEC

of 1 mg ai/ L; vascular aquatic plants were similar with a non

- definitive EC 50 

### >12.1 mg

ai/L.

D. Potential Risks to Non

- target O rganisms

The results of this screening

- level risk assessment indicate that the proposed uses for cyantraniliprole have the potential for direct adverse effects to federally listed threatened/endangered (hereafter referred to as "listed") and non

- listed mammals from chronic exposure

, listed freshwater invertebrates from acute exposures, listed estuarine/marine invertebrates from acute exposures, listed terrestrial invertebrates from

acute exposures, listed benthic invertebrates from acute exposures, and listed and non

-

### 6 listed benthic invertebrates from chronic exposures

. Direct effects to terrestrial monocots and estuarine/marine fish (chronic) cannot be excluded because of an absence of data

. Direct effects to birds (and, thus, reptiles a nd terrestrial

- phase amphibians), fish (and, thus, aquatic

- phase amphibians), aquatic plants , and terrestrial dicots are not expected from the proposed cyantraniliprole uses. Indirect effects are possible for all species that depend on aquatic invertebrat es
, estuarine/marine fish, terrestrial invertebrates, terrestrial

monocots, and/or mammals for food, habitat, or other environmental resources ( Table 1 )

.

Table 1. Listed Species Risks Associated with Potential Direct or Indirect Effects from the Proposed Applications of Cyantraniliprole

L isted Taxon D irect Effects I ndirect Effects

Terrestrial and semi

- aquatic plants

– monocots Yes 2 Yes 1

Terrestrial and semi

- aquatic plants

– dicots No Yes 1

Terrestrial in vertebrates Yes (acute) Yes 1

Birds No Yes 1

Terrestrial

- phase amphibians No Yes 1

Reptiles No Yes 1

Mammals Yes (chronic) Yes 1

Aquatic plants No Yes 1

Freshwater fish No Yes 1

Aquatic

- phase amphibians No Yes 1

Freshwater invertebrates Yes (acute) Yes 1

Benthic invertebrates Yes ( acute and chronic) Yes 1

Marine/estuarine fish Yes (chronic) 3 Yes 1

Marine/estuarine invertebrates Yes (acute) Yes 1

1 The potential for adverse effects to those species that rely on plant and/or animal species (specifically aquatic invertebrates, terrestrial invertebrates, or mammals) cannot be precluded. Indirect effects may include general habitat modification, host plant loss, and food supply disruption.

2 Based on monocot seedling emergence data gap.

3 Based on a non

- definitive (less than) NOAEC

.

### 7 E. Uncertainties and Data Gaps

There was no i ndependent l aboratory v alidation (ILV) provided for the analytical methodology used for determining DPX

- HGW86 in air described in th e study entitled

“

Analytical Method for the Determination of DPX

- HGW86 in Air Using LC/MS/MS ” (MRID 48119930).

Acceptable toxicity data are not available to assess the effects of cyantraniliprole to
estuarine/marine invertebrates from chronic exposure . In lieu of these data, the acute

- to

chronic ratio (ACR) approach was used to generate a chronic toxicity value for the

E astern oyster and mysid shrimp ( Americamysis bahia )

. Only a non

- definitive NOAEC (less than) was available for chronic effects to estuarine/marine fish. There is uncertainty

as to the lower bounds of the chronic toxicity of cyantraniliprole to estuarine/marine fish.

Only a partial set [ 1 monocot and 4 dicot yledenou s (dicots) ] of scientifically sound data were available for the seedling emergence test. Normal testing requires four monocot

and six dicot species. A primary concern is the dearth of data for monocots because t he vegetative vigor study indicated that monocots (onion) were more sensitive to cyantraniliprole than dicots. Given that only one species of monocot (corn) was tested for seedling emergence effects and it was not the onion , it is un certain that corn is representative of the most sensitive monocot

.

A larval toxicity study was not available but results from the semi

- and full

- field studies

that examined effects to honeybee larvae and brood were used as information sources.

Semi

- field studies tested up to a single maximum application rate of 0.134 lb ai/A and not

th e single maximum application rate (0.69 lb ai/A for some uses). There is uncertainty as

to whether e ffects at higher application rates are possible

.

Finally, degradate toxicity data are limited for the major degradates and the quantitative

structure

- activity model ECOSAR did not produce reliable toxicity estimates . Given the uncertainty, degradates wer e assumed to be equally toxic to the parent ; the Health Effects

Division came to this same determination

.

II PROBLEM FORMULATION

The purpose of this assessment is to evaluate the environmental fate and ecological risks for the registration of the new ch emical , cyantraniliprole

. As a new insecticide being proposed for use in the United States, EPA is required under the Federal Insecticide Fungicide and Rodenticide Act (FIFRA) to ensure that cyantraniliprole does not have the potential to cause unreasonable adverse effects to the environment. Potential effects to listed specie s are also considered under the Endangered Species Act to ensure that the registration of cyantraniliprole is not likely to jeopardize the continued existence of such listed species or adversely modify their habitat. To these ends, this assessment follows EPA guidance on conducting ecological risk assessments (USEPA 1998) and the Office

### 8 of Pesticide Program’s policies for assessing risk to non

- target and listed organisms (USEPA 2004).

Among the end products of the EPA pesticide registration process is a determination of whether a product is eligible for registration and, if so, a description of how the product may be used. A label rep r esents the legal document that stipulates how and where a given pesticide may be used. End

- use labels describe the formulation type, acceptable methods of application, where the product may be applied, and any restrictions on how applications may be condu cted. Thus, the use, or potential use, described by the pesticide’s labels is considered “the action” being assessed. This assessment is in support of the new chemical registration of cyantraniliprole

.

A. Stressor Source and Distribution

1. Source and Intensity

Cyantraniliprole, a broad spectrum insecticide , is a new chemical that is undergoing registration by DuPont and Syngenta

. I n addition to the technical, 1 3 end

- use products are being proposed for registration in the United States ( Tab le 2 ). According to the proposed label s , the product s would be used to control a wide range of insects on both agricultural and non

- agricultural areas . Cyantraniliprole is proposed as a foliar spray, bark spray, micro sprinkler chemigation, drip chemi gation, soil drench, soil treatment, seed treatment, seed piece treatment, or bait , depending on the use

.

Table 2. Cyantraniliprole Products Proposed for Registration in the United States

Product (registrant) Active Ingredients (% purity) Form Regist ration Number

A17960B ST (Syngenta) Cyantraniliprole (48.8%) NS 1 100

- RURI

A17960A ST (Syngenta) Cyantraniliprole (48.8%) NS 100

- RUEN

A16901B CP (Syngenta) Cyantraniliprole (20%) Thiamethoxam (20%) Water dispersible granule 100

- RUER

Mainspring Insecticide (Syngenta) Cyantraniliprole (20%) Thiamethoxam (20%) Water dispersible granule 100

- RUEE

A16901B Residential

and Turf (Syngenta) Cyantraniliprole (20%) Thiamethoxam (20%) Water dispersible granule 100

- RUEG /100

- RUEU

Cyazypyr Technical ( DuPont ) Cyantraniliprole (96.7%) NS 352

- ILA

Benevia Insect Control ( DuPont ) Cyantraniliprole (10.26%) Oil dispersion 352

- ILT

Dermacor Z

- 103

Insecticide Seed Treatment ( DuPont ) Cyantraniliprole (50%) Flowable suspension 352

- ILI

Exirel Insect Control ( DuPont ) Cyantraniliprole (10.2%) Oil in water emulsion 352

- ILO

Verimark Insect Control ( DuPont ) Cyantraniliprole (18.66%) Suspension concentrate 352

- IAN

HGW86 Fly Control Bait ( DuPont ) Cyantraniliprole (0.5%) Granular bait 352

- IAE

### 9 Product (registrant) Active Ingredients (% purity) Form Regist ration Number

HGW86 GH and N

Insect Control ( DuPont ) Cyantraniliprole (18.66%) Suspension concentrate 352

- IAG

HGW86 T and O Insect Control ( DuPont ) Cyantraniliprole (18.66%) Suspension concentrate 352

- IAL

HGW86 SC Insect Control ( DuPont ) Cyantraniliprole (18.66%) Suspension concentrate 352

- IAI

1 

### Not specified on label

2. Physical/Chemical/Fate and Transport Properties

Cyantraniliprole is relatively soluble (14.2 mg/L) in water and its low vapor pressure (3.85 x 10 - 17 

### mm Hg), and Henry’s Law constants (1.7 x 10 - 18 

### atm*m 3 

### /mol) suggest the chemical’s volatilization is limited. Based on a preliminary review of the data, the chemical is subject to both abiotic and biotic routes of dissipation whereby multiple degradates may form depending on environmental conditions.

3. Pesticide Ty pe, Class, and Mode of Action

Cy antraniliprole is an insecticide that belongs to the diamide class of compounds. It is structurally identical to the previously registered chlor an tran iliprole (CAS 500008

- 45

- 7)

, with the exception of a cyano

- group substituted for the chloro

- group. Cyantraniliprole binds with insect ryanodine receptors, causing unregulated activation of ryanodine receptor channels. This leads to internal calcium store depletion and impairs the regulation of muscle contractio n. Cyantraniliprole is systemically distributed in plants

and i nsects exposed to cyantran iliprole first exhibit lethargy, followed by muscle paralysis, and then death.

4. Overview of Pesticide Usage

Since this is a new chemical, the Agency does not have any usage information for cyantraniliprole

. It is anticipated that use will be widespread. Uses cover a variety of agricultural ( e.g., tree nuts, leafy vegetables, potatoes, brassica, fruiting vegetables) and

non

- agricu ltural ( e.g., turfgrass, ornamentals, fly bait, public health pests) scenarios. Application rates vary, but most seasonal maximums are 0.4 to 0.42 lb ai/A (two uses have maximums of 0.5 and 0.69 lb ai/A)

. For many of the ornamental uses, the labels speci fy a yearly maximum of 0.42; however, the agricultural crop uses express the use in

terms of seasonal maximums . For this assessment, the seasonal maximum is assumed to be a yearly maximum, but this will remain a point of uncertainty

.

B. Recepto rs

1. Aquatic and Terrestrial Effects

Table 3 gives examples of taxonomic groups and species tested to help understand potential ecological effects of pesticides to non

- target organisms. Within each of these

### 10 very broad taxonomic groups, a measure of effect from either acute or chronic exposure

is selected from the available test data.

Table 3. Taxonomic Groups and Test Species Evaluated for Ecological Effects in Screening

- Level Risk A ssessments

Taxonomic Group Example(s) of Representative Species

Birds 1 Mallard duck ( Anas platyrhynchos ) Bobwhite quail ( Colinus virginianus )

Mammals Laboratory rat ( Rattus norvegicus )

Terrestrial invertebrates Honey bee ( Apis mellifera L. )

Freshwater fish 2 Bluegill sunfish ( Lepomis macrochirus ) Rainbow trout ( Oncorhynchus mykiss )

Freshwater invertebrates Water flea ( Daphnia magna )

Estuarine/marine fish Sheepshead minnow ( Cyprinodon variegatus )

Estuarine/marine invertebrates Mysid ( Americamysis bahia)

Eastern oyster ( Crassostrea virginica )

Terrestrial plants 3 Monocots

– corn ( Zea mays )

Dicots

– soybean ( Glycine max )

Aquatic plants and algae Duckweed ( Lemna gibba )

Green algae ( Pseudokirchneriella subcapitata )

1 Birds represent surrogates for amphibians (terrestrial phase) and reptiles.

2 Freshwater fish may be surrogates for amphibians (aquatic phase).

3 Four species of two families of monocots, of which one is corn; six species of at least four dicot families, of which one is soybeans.



### 2. Ecosystems Potentially at Risk

The ecosystems potentially at risk include aquatic and terrestrial areas adjacent to the application sites and d ownstream. In addition, organisms that use the application site as part of their habitat ( e.g., birds foraging for insects within application areas) are also considered to be part of the ecosystems potentially at risk.

C. Assessment Endpoints

FIFRA Part 158 guideline toxicity tests (CFR 40 §158.630, 2009) are intended to determine pesticide effects on a variety of organisms, including birds, mammals, fish,

terre strial and aquatic invertebrates, and plants. These tests include both short

- term and long

- term exposure periods and evaluate the survival, reproduction, and/or growth of laboratory species. The studies, when available, are used to evaluate the potential of a pesticide to cause adverse effects, to determine whether further testing is required, and to determine the need for precautionary label statements to minimize the potential adverse

effects to non

- target animals and plants (CFR 40 §158.630, 2009).

Assessment endpoints are intended to represent valued attributes of the environment that, if detrimentally altered, could pose a risk to the environment. The assessment endpoints of this ecological risk assessme nt include terrestrial and aquatic animal and plant mortality following acute exposure to cyantraniliprole and terrestrial and aquatic animal reproduction, growth and survival effects from chronic exposure to cyantraniliprole

.

### 11 Surrogate species are used t o represent all freshwater fish (2000+) and bird (680+) species in the United States. For mammals, acute studies are usually limited to the Norway rat or the house mouse. Usually data from estuarine/marine testing are limited to a crustacean, a mollusk, and a fish. The assessment of risk or hazard makes the assumption that avian toxicity is similar to terrestrial

- phase amphibians and reptiles, unless more appropriate data are available. The same assumption is made for fish and aquatic

- phase amphibians. The most sensitive toxicity endpoints are used from surrogate test species to estimate treatment

- related direct effects on mortality and reproductive and growth assessment endpoints.

For terrestrial and semi

- aquatic plants, the screening assessment end points for non

- target species (crops and non

- crop plant species) are based on the emergence of seedlings and vegetative vigor of annuals. Measures of effect for this assessment focus on alterations to plant emergence and/or to active growth.

For aquatic plants, the assessment endpoint is the maintenance and growth of standing crop or biomass. Measures of effect for this assessment focus on non

- vascular, e.g. , algae, and vascular plant, e.g. , duckweed ( Lemna gibba ), growth rates and biomass

measurements.

The Agency acknowledges that pesticides have the potential to exert indirect effects upon listed organisms by, for example, perturbing forage or prey availability, altering the extent of nesting habitat, and creating gaps in the food chain. In conductin g a screen for indirect effects, the endpoints for each taxonomic group are used to make inferences concerning the potential for indirect effects upon listed species that rely upon non

- listed organisms as resources critical to their life cycle.

The endpoi nts are typically derived from registrant

- submitted studies which have undergone review and were classified as “acceptable” (conducted under guideline conditions and considered to be scientifically valid) or “supplemental” (conditions deviated from guideli nes but the results are considered to be scientifically valid). For more details on EFED’s study classification system and study guidelines, see USEPA

2004.

Assessment endpoints can also be derived from the open literature. Guidelines for incorporation of open literature into ecological risk assessments are described in USEPA (2004). Toxicity data from the open literature are identified via the ECOTOX 1 

### search engine, maintained by the U.S. EPA Office of Research and Developm ent (ORD). T o be included in the ECOTOX database, papers must meet several criteria. Data that pass the ECOTOX screen are evaluated relative to the data provided by the registrant, and may be incorporated qualitatively or quantitatively into the risk ass essment. Specific studies may

warrant inclusion in the risk assessment when:

(1) tested endpoints are more sensitive than those in registrant data; (2) the test data are based on under

- represented taxa;

1 USEPA 2011. Ecotoxicity database http://cfpub.epa.gov/ecotox/

### 12 (3) the data include ecologically relevant endp oints not normally evaluated in registrant studies

There was one cyantraniliprole stud y (Jacobson and Kennedy 2011) from the open

literature that was identified in the public version of ECOTOX (available at: http://cfpub.epa.gov/ecotox/quick_query.htm ). The study was performed on the tobacco thrip ( Frankliniella fusca ) ; however, it was not useable for the ri sk assessment because the dose of cyantraniliprole was given in milligrams per plant rather than on a per acre

basis. Therefore, no ecotoxicity data from the open literature are included as assessment endpoints.

Although all endpoints are measured at the individual level, they can provide some insight about the potential for adver se effects at higher levels of biological organization ( e.g . populations and communities). For example, pesticide effects on individual survivorship have important implications for both population rates and habitat carrying capacity.

D. Conceptual Model

The conceptual model used to depict the potential ecological risk associated with cyantraniliprole is fairly generic and assumes that as a n insecticide

, cyantraniliprole is capable of affecting terrestrial and aquatic organism s (animals and plants) provided environmental concentrations are sufficiently elevated as a result of proposed label uses. Therefore, the risk assessment will consider potential exposure as a result of direct applications, spray drift, and runoff.

1. Risk Hypotheses

For this assessment, the risk to non

- target organisms is based on potential effects from the application of cyantraniliprole to the environment. The Agency presumes the following risk hypothesis for this screening level assessment:

B ased on mode of action, the proposed use patterns, and the sensitivity of non

target aquatic and terrestrial species, the proposed uses of cyantraniliprole have the potential to reduce survival, reproduction, and/or growth in terrestrial and aquatic animals and plants through direct application, spray drift and/or runoff.

F or a chemical to pose an ecological risk, it must reach non

- target or ganisms at

concentrations found to cause adverse effects. The analysis of ecological exposure pathways in this assessment includes an examination of the source and potential migration pathways to cyantraniliprole exposure, and the determination of potenti al

adverse effects on non

- target species.

### 13 2. Diagram

Application methods for cyantraniliprole involve foliar spray applications via ground equipment and aerial equipment, seed treatments, micro sprinkler chemigation, dri p chem igation, soil treatments, soil drenches, and baits . Ecological receptors that may potentially be exposed to cyantraniliprole include terrestrial and semi

- aquatic wildlife ( i.e. , mammals, birds, amphibians, terrestrial invertebrates, and reptiles) an d plants. In addition, aquatic receptors ( e.g ., freshwater and estuarine/marine fish and invertebrates, amphibians, and plants) may also be exposed as a result of potential movement of cyantraniliprole via spray drift and/or runoff from the site of application to aquatic environments. The assessment following the process depicted in Figure 1 (aquatic exposure) and Figure 2 (terrestrial exposure) forms the basis for identifying potential endpoints, stre ssors, and ecological effects associated with cyantraniliprole use.

Exposure to terrestrial animals is based primarily on dietary consumption of foliar residues while aquatic assessments assume that all major potential routes of direct

exposure are accoun ted for.

Stressor

Source

Receptors

Attribute Change Cyantraniliprole Applications (and degradates)

– All Uses

Spray drift

Aquatic animals

Invertebrates

Vertebrates

Individual organisms

Reduced survival Reduced growth Reduced reproduction Food chain Reduction in algae and

vascular plants Reduction in prey

Modification of PCEs

related to prey availability Habitat integrity Reduction in primary productivity

Reduced cover Community change

Modification of PCEs related to

habitat Surface water/

Sediment Runoff

Aquatic Animals

Invertebrates

Vertebrates Exposure

Media

Uptake/gills or integument

Ingestion Ingestion Atmospheric
transport

Wet/dry deposition Soil Leaching to

Groundwater

Uptake/gills or integument

Aquatic Plants

Non

- vascular

Vascular Uptake/cell, roots, leaves Riparian plants

terrestrial

exposure pathways see

Figure 2

Figure 1 : Conceptual model depicting stressors, exposure pathways, and potential effects to aquatic organisms from the proposed uses of cyantraniliprole . Dotted lines indicate exposure pa thways that are hypothesized to have a low likelihood of contributing to ecological risk.

### 14 Stressor

Source

Attribute Change Cyantraniliprole Applications (and degradates)

– All Uses

Direct application Spray drift

Terrestrial

vertebrates Terrestrial

Inverts

Individual organisms

Reduced survival Reduced growth Reduced reproduction Food chain Reduction in prey and food

Modification of PCEs related to prey availability Habitat integrity Reduction in primary productivity

Reduced cover Community change

Modification of PCEs related

to habitat Terrestrial plants grasses/forbs, fruit, seeds (trees, shrubs) Runoff

Terrestrial

vertebrates Exposure Media & Receptors Soil

Ingestion

and contact Ingestion Dermal uptake/Ingestion Atmospheric
transport

Root uptake/contact

Wet/dry deposition

Ingestion Leaching to

Groundwater Irrigation

water

Figure 2 : Conceptual model depicting stressors, exposure pathways, and potential effects to terrestrial organisms from the proposed uses of cyantraniliprole . Dotted lines indicate exposure pathways that are hypothesized to have a low likelihood of contributing t o ecological risk.



### E. Analysis Plan

As with any pesticide, there is concern regarding the potential effects cyantraniliprole use may pose to non

- target animals and plants. This document characterizes the

environmental fate of cyantraniliprole to assess whether its proposed label provide a means of exposure to non

- target species. Additionally, the toxicity of cyantraniliprole is characterized, then both potential exposure and effects are integrated to estimate the

likelihood o f advers e effects (risk) to non

- target listed and non

- listed animals and plants that could potentially affect the registration decision of cyantraniliprole under the Federal Insecticide, Fungicide and Rodenticide Act (FIFRA), the Food Quality Protection Act (FQPA), and the Endangered Species Act (ESA).

The maximum proposed label application rates for the new use s of cyantraniliprole were selected for modeling environmental concentrations for this screening

- level deterministic (risk

- quotient based) assessment. The most sensitive toxicity endpoints from surrogate test species are used to estimate treatment

- related effects on growth, an d survival. The aquatic estimated environmental concentrations (EECs) are based on the parent and the

ten degradates of concern using a total toxic residue (TTR) approach. Given that a default 35

- day foliar half

- life is used in the terrestrial modeling, the terrestrial EECs are expected to account for both the parent and its ten degradates of concern (even though only the parent chemical is modeled).

### 15 In the following sections, the environmental fate and ecological effects of cyantraniliprole are characte rized using a risk quotient (ratio of exposure concentration to effects concentration) approach

. Although risk is often defined as the likelihood and magnitude of adverse ecological effects, the risk quotient

- based approach does not provide a quantitative estimate of likelihood and/or magnitude of an adverse effect. Such estimates may be possible through a more refined, probabilistic assessment; however, they are beyond the scope of this screening

- level assessment.

1. Preliminary Identification o f Data Gaps

The following data gaps were identified in this risk assessment:

Environmental Fate:

• No i ndependent l aboratory v alidation (ILV) was provided for the analytical

methods used to determine DPX

- HGW86 in air

.

Ecological Effects:

• Data were not available for the chronic toxicity to an estuarine/marine invertebrate species.

2. Measures to Evaluate Risk Hypotheses and Conceptual Model

a. Measures of Exposure

T o estimate risks of cyantraniliprole exposures in aqu atic and terrestrial environments, all exposure modeling and resulting risk conclusions will be made based on maximum proposed application rates ( Table 5 ) . Measures of exposure are based on aquatic and

terrestrial models that estimate environmental concen trations of cyantraniliprole using maximum proposed labeled application rates and application methods that have the greatest potential for off

- site transport of the chemical

. Aquatic chemical concentrations are estimated using PRZM/EXAMS for surface wate r and the Tier I model, Screening Concentration in Ground Water (SCI

- GROW, v2.3), for groundwater. Additionally, the Screening Imbibition Program (SIP) and the Screening Tool for Inhalation Risk (STIR)

are used to determine if drinking water and/or inhala tion, respectively, are potentially significant routes of concern for terrestrial animals. The models indicated that exposure through the drinking water or inhalation routes are unlikely to cause acute or chronic effects in birds and mammals ( Appendices A and B ).

Exposure estimates for terrestrial animals and insects assumed to be in the target area or in an area exposed to spray drift for the foliar spray, bark spray, and public health uses are derived using the T

- REX model (version 1.5.1, 8/20/2012). T

- REX also models exposures to terrestrial wildlife via seed treatments and granular applications; these analyses do not consider the spray drift exposure pathway. The model incorporates the Kenaga nomograph, as modified by Fletcher et al. (1994), which is based on a large set of actual field residue data. The upper

- limit values from the nomograph represent the

95 th 

### percentile of residue values from actual field measurements (Hoerger and Kenaga

### 16 1972). The Fletcher et al. (1994) modi fications to the Kenaga nomograph are based on measured field residues from 249 published research papers, including information on 118 species of plants, 121 pesticides, and 17 chemical classes.

Exposure to upland and wetland plants is estimated using the TerrPlant (v1.2.1) screening

model. The model examines spray drift and runoff as potential exposure pathways from a treated field adjacent to non

- target species.

The Residues of Concern Knowledgebase Subcommittee (ROCKS) determined ( DP

Barcode D 40441 1 ) that parent cyantraniliprole and 10 of its degradation products (IN

J9Z38, IN

- NXX69, IN

- QKV54, IN

- RNU71, IN

- JSE76, IN

- JCZ38, IN

- K5A78, IN

K5A77, IN

- K5A79, and IN

- PLT97) should be considered as residues of concern when evaluating human drinking water (se e Appendix C for structures and basic information)

. These degradates will be considered in the ecological risk assessment as well.

The AgDRIFT spray drift model (v2. 1 .1 ) is used to assess exposures of organisms to cyantraniliprole deposited on terrestrial habitats by spray drift.

b. Measures of Effect

Measures of effect are obtained from a suite of registrant

- submitted guideline studies conducted with a limited number of surrogate species. The test species are not intended to be representative of the most sensitive species but rather are selected based on their ability to thrive under laboratory conditions. The acute measures of effect routinely used

for listed and non

- listed animals in screening le vel assessments are the LD 50 

### , LC 50 

### or EC 50 

### , depending on taxa ( Table 3 ). LD stands for "Lethal Dose", and LD 50 

### is the amount of a material, given all at once, that is estimated to cause the death of 50% of a group of test organisms. LC stands for “Lethal Concentration” and LC 50 

### is the concentration of a chemical that is estimated to kill 50% of a sample population. EC stands for “Effective

Concentration” and the EC 50 

### is the concentration of a chemical that is estimated to produce some measured effect in 50% of the test population. Endpoints for chronic measures of exposure for listed and non

- liste d organism s are the NOAEL or NOAEC.

NOAEL stands for “No Observed

- Adverse

- Effect

- Level” and refers to the highest tested dose of a substance that has been repo rted to have no harmful (adverse) effects on a test population. The NOAEC ( i.e ., “No

- Observed

- Adverse

- Effect

- Concentration”) is the highest test concentration at which none of the observed results were statistically

different from the control. For non

- li sted plants, only acute exposures are assessed ( i.e

., EC 25 

### for terrestrial plants and EC 50 

### for aquatic plants). For listed terrestrial plants the Agency uses the EC 0 5 

### or NOAEC ( Table 4 ).

Table 4

. Acute and Chronic Measures of Effect

TAXA ASSESSMENT MEASURE OF EFFECT

Aquatic Animals ( f reshwater fish

and invertebrates and

e stuarine/marine fish and

invertebrates ) Acute Lowest tested EC 50 or LC 50 (acute toxicity tests)

Chronic Lowest NOAEC (early life

- stage or full life

- cycle tests)

### 17 TAXA ASSESSMENT MEASURE OF EFFECT

Terrestrial Animals

Birds Acute/Sub

- acute Lowest LD 50 (single oral dose) and LC 50 (sub

- acute dietary)

Chronic Lowest NOAEC (21

- week reproduction test)

Terrestrial Animals

Mammals Acute Lowest LD 50 (single oral dose test)

Chronic Lowest NOAEC (two

- generation reproduction test)

Terrestrial In vertebrates Acute Lowest LD 50 (acute contact toxicity test)

Plants

Terrestrial non

- listed (monocots and dicots) Acute/Chronic Lowest EC 25 (seedling emergence and vegetative vigor)

Plants Terrestrial listed (monocots and dicots) Acute/Chronic EC 05 or NOAEC associated with the lowest EC 25 (seedling emergence and vegetative vigor)

Plants Aquatic non

- listed (vascular and

non

- vascular) Acute/Chronic Lowest EC 50



### III. ANALYSIS

A. Use Characterization

Proposed cyantraniliprole uses include: bushberries, citrus, cotton, oil seeds, pome fruit, stone fruit, tree nuts, vegetables (bulb, corm and tuberous, cucurbit, fruiting, leafy brassica, and leafy non

- brassica), and profe ssional products (fly bait, indo or and outdoor insect control for public health pests such as cockroaches, ants, flies and termites, nuisance insect pests and turfgrass and ornamentals). Cyantraniliprole is appl ied via foliar spray, bark spray, micro sprinkler chemigation, drip chemigation , soil drench, soil treatment, seed treatment, seed piece treatment, or bait. Rates are listed in Table 5

.

Table 5

. Application Information from the Proposed Cyantraniliprole New Uses

Crop Product Method # apps Min

interval Single max (lb ai/A) Seasonal

maximum

(lb ai/A)

Brassica vegetables A 16901B CP

Insecticide Soil 1 NS 0.35 0.4

Brassica leafy vegetables A 16901B CP

Insecticide Foliar (aerial, ground) 2.3 a 7 days 0.175 0.4

Brassica leafy v egetables Exirel High volume spray

broadcast by ground, low volume spray

- aerial 3 a 5 days 0.133 0.4

Bushberries Exirel High volume spray

– broadcast by ground, low 3 a 5 days 0.133 0.4

### 18 Crop Product Method # apps Min

interval Single max (lb ai/A) Seasonal

maximum

(lb ai/A)

volume spray

- aerial

Citrus Exirel High volume spray

broadcast by ground, low volume spray

- by air, low volume fogger spray by ground 3 a 7 days 0.133 0.4

Citrus Verimark Soil drench or micro sprinkler chemigation 2 7 days b 0.391 0.4

Cotton Benevia High volume spray

broadcast by ground, low volume spray

- aerial 3 a 7 days 0.133 0.4

Cucurbits A 16901B CP

Insecticide Foliar (aerial, ground) 2.3 a 5 days 0.175 0.4

C ucurbit s Verimark Soil application by drip 2 10 days 0.130 0.4

Cucurbits A 16901B CP

Insecticide Soil (furrow, at transplant, knifing, shanking, drip chemigation) 1 NS 0.35 0.4

Fruiting vegetables A 16901B CP

Insecticide Foliar (aerial, ground) 2.3 a 5 days 0.175 0.4

Fruiting v egetables Verimark Soil application by drip 2 5 days c 0.130 0.4

Fruiting vegetables A 16901B CP

Insecticide Soil (furrow, at transplant, knifing, shanking, drip chemigation) 1 NS 0.35 0.4

Leafy vegetables A 16901B CP

Insecticide Soil (furrow, at transplant, knifing, shanking, drip chemigation) 1 NS 0.35 0.4

Leafy vegetables A 16901B CP

Insecticide Foliar (aerial, ground) 2.3 a 7 days 0.175 0.4

Leafy v egetables ( except
brassica ) Exirel High volume spray

broadcast by ground, low volume spray

- aerial 3 b 5 days 0.133 0.4

Oil seeds Benevia High volume spray

broadcast, low volume

spray

- aerial 3 b 7 days 0.133 0.4

Pome fruit Exirel High volume spray

broadcast by ground, low volume spray

- aerial 3 7 days 0.133 0.4

Potatoes A17960A ST

and A17960B

ST Seed treatment NS NS 0.69 7

Potatoes Verimark Seed piece treatment 1 NS 0.176 0.4

C orm and tuberous vegetables Benevia High volume spray

broadcast by ground or overhead chemigation, low volume spray

- aerial 3 b 5 days 0.133 0.4

Corm and t uberous vegetables A 16901B CP

Insecticide Soil 1 NS 0.25 0.4

### 19 Crop Product Method # apps Min

interval Single max (lb ai/A) Seasonal

maximum

(lb ai/A)

Rapeseed including canola varieties, mustard

seed Dermacor Seed treatment 1 NS 0.4 0.4

Stone fruit Exirel High volume spray

broadcast by ground, low volume spray

- aerial 3 7 days 0.133 0.4

Sunflower A17960A ST

and A17960B

ST Seed treatment NS NS 0.016 1 0.016

Tree nuts Exirel High volume spray

broadcast by ground, low volume spray

- aerial 3 7 days 0.133 0.4

Bulb v egetables Benevia High volume spray

broadcast by ground or overhead chemigation, low volume spray

- aerial 3 b 5 days 0.133 0.4

Flowerbeds and groundcovers HGW86

T&O Insect

Control Broadcast (ground) 2 b 7 days d 0.208 0.42

Ornamentals treated by

commercial and consumer applicators A 16901B

Residential Foliar 2 7 days 0.13 9 0.26

Ornamental plants, fruit and nut trees (non

bearing) and forest seedlings grown in greenhouses, lath and

shade houses, containers,

field nurseries and interiorscapes Mainspring Foliar (ground) 1.6 b 14 days 0.26 0.42

Ornamental plants, fruit and nut trees (non

bearing) and forest seedlings grown in greenhouses, lath and shade houses, containers,

field nurseries and interiorscapes Mainspring Soil drench 1.6 b 14 days 0.26 0.42

Ornamental plants (exterior landscapes and interior plantscapes HGW86

T&O Insect

Control Foliar (ground) Bark application NS 7 days 0.42 0.42

Ornamental plants (exterior landscapes and interior plantscapes HGW86

T&O Insect

Control Soil treatment (drench and injection) NS NS 0.42 lb

ai/A 5 0.42 lb ai/A

Trees (including non

bearing fruit and nut trees), shrubs, evergreens, foliage plants, groundcovers, vines, interior plantscape plants HGW86 GH

& N Insect

Control Soil treatment (drench and injection) NS NS 0 .42 lb

ai/A 5 0.42 (per year)

### 20 Crop Product Method # apps Min

interval Single max (lb ai/A) Seasonal

maximum

(lb ai/A)

Trees (including non

bearing fruit and nut trees), shrubs, evergreens, bedding plants, flowering plants, flowers, foliage plants, groundcovers, vines, interior plantscape plants, vegetable transplants (fruiting, leafy, tuberous, corm) HGW86 GH

& N Insect

Control Foliar (ground) NS NS 0.42 0.42 (per year)

Turf , golf courses, residential lawns, commercial grounds, parks, playgrounds, athletic fields, sod farms A 16901B

Turf Broadcast (ground) 2 30 days 0.26 0.42

Grassy, weedy, mulched,

or bare soil areas in and around greenhouses, nurseries, interior plantscapes, lath and

shade house , under trees and shrubs that are being grown in

- ground HGW86 GH

& N Insect

Control Broadcast (ground) 1.6 b 30 days e 0.26 0.42 (per year)

Fly control bait HGW86 Fly

Control Bait Broadcast (ground) NS 7 days 0. 0 87 lb

ai/A 0.44

Public health insect

control HGW86 SC

Insect

Control Spot, crack and crevice

spray NS 7 days 0.42 5 0.42

Potted ornamentals HGW86

GH&N Insect

Control Soil drench NS NS 0. 5 5 0. 5 (per year) 9

Potted ornamentals Mainspring Soil drench NS NS 0.13 9 0.26

NS

– not specified

1 Based on 0.00000044 lb ai/seed * 4 lb seed/A * 9000 seeds/lb (USEPA 2011b)

5 Based on seasonal maximum application rate

7 Based on 0.00013 lb ai/lb potato * 5271 lb potato/A (T

- REX)

9 Based on communication with registrant

a Assumed based on seasonal maximum rate

b Assumed based on citrus foliar use

c Assumed based on fruiting vegetable foliar use

d Assumed based on other ornamental uses

e Assumed based on turf use



### B. Exposure Characterization

Cyantraniliprole is a new systemic, cross

- spectrum insecticide belonging to the diamide class of chemistry, moving both in the xylem and ph loem of vascular plants . Its major routes of dissipation include alkaline hydrolysis, photo degradation in aqueous and moist soil environments, and aerobic and anaerobic biotransformation in terrestrial and aquatic

### 21 environments. The most prominent dissip ation pathways include alkaline hydrolysis and aqueous photolysis with calculated half lives reported in hours. Table 6 provides a summary of cyantraniliprole’s environmental fate profile.

Table 6. Environmental Fate Profile Summary for Cyantraniliprole

Parameter Value MRID #

Common name Cyantraniliprole 48894801

CAS number 736994

- 63

- 1 48894801

Chemical name 3

- Bromo

- 1

- (3

- chloro

- 2

- pyridinyl)

- N

- [4

- cyano

2

- methyl

- 6

- [(methylamino)carbonyl]phenyl]

- 1H

- pyrazole

- 5

- carboxamide 48894801

Chemical Class Chemical Category Diamide

Insecticide 48894801

Empirical formula C 19 H 14 BrClN 6 O 2 48894801

Structure 48894801

Molecular Mass 473.72 g/mole 48119904
Water Solubility (20 ° C) 14.2 mg/L (R.O. water) 48119901

Vapor pressure (20 ° C) 3.85 x 10 - 17 mm Hg 48122593

Henry’s Law Constant(20 ° C) 1.70 x 10 - 18 atm m 3 /mol 48119907

Partition coefficient (P

ow ) 79 (log Pow = 1.9) 48119904

Dissociation Constant pKa = 8.8 48119909

Hydrolysis (t 1/2 )

(25 ° C) pH 4 = 222 days pH 7 = 31 days pH 9 = 0.86 days (21 hrs) 48119905

Aqueous Photolysis (t 1/2 ) 0.33 days (8 hrs) 48119906

Soil Photolysis 12.5 days (moist soil) stable (dry soil) 48120082

48120046

Aerobic Soil Metabolism

(t 1/2 ) 16.2 days 89.4 days 48120045

Anaerobic Soil Metabolism (t 1/2 ) 4.3 days 48120047

Aerobic Aquatic Metabolism (t 1/2 ) 3.9 days 25.1 days 48120049

Anaerobic Aquatic Metabolism (t 1/2 ) 2.4 days 12 days 48120071

48120081

Soil Partition Coefficient (K

oc ) 241 mL/g o.c (mean) 48120073 N N

N N H

O Cl Br

N H O

N

### 22 Parameter Value MRID #

Terrestrial Field Dissipation (DT 50 ) 3.5

- 10.2 days (CA)

3.4

- 9.7 days (WA)

6

- 44 days (MO)

21.6 days (NY)

16.7 days (TX)

13.5 days (Canada) 48120055

48120054

48120056

48120053

88120058

48120057

Bioaccumulation in Fish (BCF) < 1 in fillet, carcass & whole fish 48120139



### 1. Environmental Fate and Transport Characterization

a. Degradation

Considering abiotic degradation, cyantraniliprole’s hydrolytic degradation appears to be pH dependent, with degradation increasing with increasing pH (alkinity) . This is evident

in the DT 50 

### profile. The DT 50 

### values decrease from 222 days (stable) at pH 4 to 31 days at pH 7 to 0.86 days at pH 9 (T = 25oC; MRID 48119905).

Photo degradation appears to be a major degradation pathway in aqueous an d moist soil

environments. The aqueous photolysis study shows a photo transforma tion half

- life of about 7.9 hours or 0.33 days (MRID 48119906). Soil photolysis studies were conducted

with both a moist soil where soil moisture was maintained and an air

- dried soil where the

soil was allowed to air

- dry over time. The moist

- soil DT 50 

### va lue was 12.5 days (MRID 48120082) whereas the compound was considered stable in the air

- dried soil photolysis study since the extrapolated half

- life of 308 days was well beyond the duration of the 15 day study period (MRID 48120046).

Biodegradation is a n effective dissipation pathway for cyantraniliprole, with anaerobic biodegradation occurring at a faster rate than aerobic biodegradation in terrestrial and aquatic environments. However, alkaline hydrolysis may contribute to some dissipation

since the l ower DT 50 

### values are associated with higher pHs. Illustrating this point, aerobic system DT 50 

### values ranged from 16.2 days in a silty clay loam soil (pH 8.05) to 89.4 days in a sandy loam soil (pH 4.62) in an aerobic soil metabolism study conducted at

20o C (MRID 48120045). In addition, the DT 50 

### values ranged from 3.9 days in a silt loam

sediment

- water system (pH 7.7) to 25.1 days in a loamy sand sediment

- water system (pH 5.6) in an aerobic aquatic metabolism study conducted at 20oC (MRID 48120049). It i s important to note, other than the degradate IN

- JCZ38, all other aerobic soil metabolism degradate half life values are significantly longer than the parent cyantraniliprole ( Table

7 ).

In anaerobic systems, the DT 50 

### value was 4.3 days in a sandy loam soi l (pH 8.05) conducted in an anaerobic soil metabolism study conducted at 20oC (MRID 48120047). In addition, the DT 50 

### values ranged from 2.4 days in a sandy loam sediment

- water s ystem (pH 6.9; MRID 48120071) to 12 days in a sandy sediment

- water system (pH 6.6) in an anaerobic aquatic metabolism study conducted at 20oC (MRID 48120081

### 23 Table 7 . Aerobic Soil Metabolism Half

- Life Summaries for Cyantraniliprole and its Degradates

Chemical ID Soil Texture DT 50 

### (days) MRID

Cyantraniliprole Gross

- Umstadt

Sassafras

Lleida Silt Loam Sandy Loam Silty Clay Loam 41.2

89.4

16.2 48120045

IN

- J9Z38 Gross

- Umstadt

Nambshiem

Sassafras

Lleida

Tama Silt Loam Sandy Loam

Loam Silty Clay Loam Silty Clay Loam 118

77.1

200

104

179 48120060

IN

- JCZ38 Gross

- Umstadt

Nambshiem

Sassafras

Lleida

Tama Silt Loam Sandy Loam

Loam Silty Clay Loam Silty Clay Loam 11.6

3.48

10.1

4.81

9.41 48120061

IN

- JSE76 Gross

- Umstadt

Nambshiem

Sassafras

Lleida

Tama Silt Loam Sandy Loam

Loam Silty Clay Loam Silty Clay Loam 219

84.9

336

157

840 48120062

IN

- K5A77 Gross

- Umstadt

Nambshiem

Sassafras

Lleida

Tama Silt Loam Sandy Loam

Loam Silty Clay Loam Silty Clay Loam 294

23.8

340

25.9

78.6 48120064

IN

- K5A78 Gross

- Umstadt

Nambshiem

Sassafras

Lleida

Tama Silt Loam Sandy Loam

Loam Silty Clay Loam Silty Clay Loam 308

1055

94

517

241 48120063

IN

- K5A79 Gross

- Umstadt

Nambshiem

Sassafras

Lleida

Tama Loam

Loam Sandy Loam

Silty Clay Silty Clay 46

25

107

19

131 48120070

IN

- PLT97 Gross

- Umstadt

Nambshiem

Sassafras

Lleida

Tama Loam Sandy Loam

Loam Silty Clay Silty Clay Loam 1638

711

1837

439

429 48120074

IN

- QKV54 Gross

- Umstadt

Nambshiem

Sassafras

Lleida

Tama Loam Sandy Loam Loamy Sand Clay Silty Clay Loam 1187

139

462

58

184 48120083

IN

- RNU71 Gross

- Umstadt

Nambshiem

Sassafras

Lleida

Tama Loam Sandy Loam Loamy Sand Clay Silty Clay Loam 107

42

400

43

28 48120087

Rate of degradation in aerobic soils at 20 degrees C and 40

- 60% MWHC except for IN

- K5A79 which was studied at 19 degrees C (Sassafras) and 24 degrees C (all other soils) and 40

- 60% MWHC.



### Chemical structures for the parent compound and its principle degra dates can be found

in Appendix C

.

### 24 b. Mobility and Transport

Cyantraniliprole appears not to volatilize. This is supported by its solubility (14.2 mg/L at 20oC; MRID 48119901) and low vapor pressure (3.85 x 10 - 17 

### mm Hg at 20oC; MRID 48122593) and Henry’s Law constant (1.7 x 10 - 18 

### atm*m 3 

### /mol at 20oC; MRID 48119907). In addition, bioaccumulation data indicate that cyantraniliprole is not likely

to bioaccumulate ( BCF < 1 in whole fis h

, MRID 48120139 )

.

Batch equilibrium studies have been conducted with the same soils on cyantraniliprole and its degradates. Cyantraniliprole is characterized as being moderately mobile based on its organic carbon partition coefficient (K

oc 

### = 157 to 376 mL/g

oc 

### ; MRID 48120073) in the test soils (FAO Classification; USEPA, 2006). Cyantraniliprole degradates have

measured K

oc 

### values ranging from 14 to 32,152 mL/g organic carbon indicating that some degradates are more mobile than the parent and some are less mobile than the parent (Table 8 ) and would be likely to sorb to organic matter in soil and sediments

.

Table 8 . FAO Mob ility Classification of Cyantraniliprole and its Degradates

Mobility Class Chemical ID K

oc Range (mL/g

oc ) Mean K

oc (mL/g

oc ) MRID

Mobile IN

- JSE76 14

- 65 30 48120067

IN

- K5A79 24

- 85 46 48120072

Moderately Mobile IN

- RNU71 104

- 181 146 48120088

IN

- JCZ38 124

- 482 239 48120066

DPX

- HGW86* 157

- 376 241 48120073
Moderately Mobile

- Slightly Mobile IN

- K5A78 412

- 2545 1048 48120068

IN

- PLT97 701

- 5029 2044 48120075

Slightly Mobile

-

Hardly Mobile IN

- J9Z38 4500

- 18526 8705 48120065

IN

- K5A77 3707

- 25306 9611 48120069

IN

- QKV54 8571

- 32152 14481 48120086

* DPX

- HGW86 represents the chemical ID for the parent cyantraniliprole.



### c. Field Studies

In terrestrial field dissipation studies, cyantraniliprole dissipated with DT 50 

### s ranging from 3.4 to 44 days ( Table 9 ). Seven degradates formed as cyantraniliprole degraded including IN

- J9Z38, IN

- JCZ38, IN

- JSE76, IN

- K5A77, IN

- K5A78, IN

- K5A79 and IN

PLT97. The majority of residues detected was confined to the uppermost soil layers (0

- 2

to 2

- 6 inches) with a small amount of the parent or degradates detected below the 12 inch soil layer, indicating a general lack of downward mobility or leaching under the study conditions. The most common degradates formed were IN

- J9Z38 (~10%), IN

- JCZ38 (~8%), IN

- JSE76 (~10%), and IN

- K5A7 8 (~10%). Table 9 illustrates the DT 50 

### profile.

### 25 Table 9 . Terrestrial Field Dissipation Half

- Life Summaries

MRID Location

Duration Plot Type DT 50 (days)

48120055 CA (539 days) Bare Soil Cropped Lettuce 10.2

3.5

48120054 WA (534 days) Bare Soil Cropped Potato 9.7

3.4

48120056 MO (541 days) Bare Soil Cropped Alfalfa 44.0

6.0

48120053 NY (514 days) Bare Soil 21.6

48120058 TX (539 days) Bare Soil 16.7

48120057 CANADA (502 days) Bare Soil 13.5



### d. Degradates

Eight major degradates ( e.g ., those present at ≥10% applied radioactivity) of cyantraniliprole include: IN

- J9Z38, IN

- NXX69, IN

- QKV54, IN

- RNU71, IN

- JSE76, IN

JCZ38, IN

- K5A78, and IN

- PLT97. The majority of these degradates formed under both

microbial

- mediated and abiotic processes. The degr adates IN

- J9Z38, IN

- RNU71, IN

JSE76, IN

- JCZ38, and IN

- K5A78 continued to increase over time to the termination of various fate studies. In addition, IN

- K5A77, IN

- K5A79, and IN

- PLT97 were detected in terrestrial field studies, making it important to consid er them as r esidues of concern. Consequently, the Health Effects Division's Residues of Concern Knowledgebase

Subc ommittee (ROCKS) has determined (DP 404411) that the following 10 degradates

are of concern and they will be considered as part of this risk assessment. The residues of

concern include: IN

- J9Z38, IN

- NXX69, IN

- QKV54, IN

- RNU71, IN

- JSE76, IN

- JCZ38,

IN

- K5A78, IN

- PLT97, IN

- K5A77 and IN

- K5A79. Therefore, the EECs represent the

combined residues of the insec ticide cyantraniliprole plus the se 10 degradation products. For structures of the degradates and t he parent, please see Appendix C

.

e. Total Toxic Residues (TTR)

To follow the total toxic residue (TTR) approach, half lives were recalculated to

collective ly account for the parent and the combined residues of concern. These values will be utilized in PRZM/EXAM modeling to generate aquatic exposure estimates. TTR half lives for aqueous photolysis, aerobic soil metabolism and aerobic aquatic metabolism

corr espond to 88 days, 1327 days, 589 days and 961 days, respectively. The hydrolysis

half life was considered stable since a half life could not be calculated due to the lack of degradation needed to fit a degradation curve. In addition, the lowest Koc valu e of 14 mL/g o.c., was selected among parent and degradate batch equilibrium studies.

### 26 2. Measures of Aquatic Exposure

a. Aquatic Exposure Modeling

The Pesticide Root Zone Model ( PRZM ; v3.12.2, May 2005) and the Exposure Analysis Model System ( EXAMS ; v2.98.4.6, April 2005) are screening simulation models coupled

with the PRZM/EXAMS (PE) graphical user interface (v5.0, November 2006) to generate daily exposures and 1

- in

- 10

- year EECs of cyantraniliprole TTR that may occur

in surface water bodies a djacent to application sites receiving cyantraniliprole through runoff and spray drift. PRZM simulates pesticide application, movement and transformation on an agricultural field and the resultant pesticide loadings to a receiving water body via runoff, e rosion, and spray drift ; EXAMS simulates the fate of the pesticide and resulting concentrations in the water body. The standard watershed geometry used for ecological pesticide assessments assumes application to a 10

- hectare agricultural field that drains into an adjacent 1

- hectare water body that is 2 meters deep (20,000 m 3 

### volume) with no outlet. The composite model PRZM/EXAMS is used to estimate screening

- level exposure of aquatic organisms to cyantraniliprole. The measure of exposure for aquatic species is the 1

- in

- 10

- year peak or rolling mean concentration.

The 1

- in

- 1 0

- year peak is used for estimating acute exposures of direct effects to aquatic organisms. The 1

- in

- 10

- year 60

- day mean is used for assessing the effects to fish and aquatic

- phase amphibians from chronic exposure. The 1

- in

- 10

- year 21

- day mean is used

for assessing the effects on aquatic invertebrates from chronic exposure.

Since there was no PRZM/EXAM scenario available to model fly and insect control applications, the Generic Estimate Environmental Concentration 2 ( GENEEC2 ) model was employed. The GENE EC2 model is a Tier I model which uses the soil/water partition coefficient and degradation kinetic data to estimate runoff from a 10

- hectare

field into a 1

- hectare by 2

- meter deep "standard" pond. Additional information on this

and other models can be fo und at: http://www.epa.gov/oppefed1/models/water/index.htm

.

Registrant

- submitted acute toxicity data were available for nine of the ten degradates identified by the ROCKS committee ( USEPA 2012c and DP 404411 ) and indicated that the degradates were less to xic than the parent for freshwater invertebrates ( Daphnia

magna ). One chronic endpoint was available for the most toxic of the degradates and it was also much less toxic than the parent . The implications of these data are discussed

further in the Risk De scription section

. No data were available for other aquatic species,

thus ECOSAR was used to predict the toxicity of the degradates for other aquatic species (fish, estuarine/marine invertebrates, aquatic plants) . H owever, its predictions were poor

when compared with actual toxicity data . Given that toxicity information was not

available for fish, estuarine/marine invertebrates, and aquatic plants, and that ECOSAR

was deemed unreliable , it is assumed that the toxicity of the ten degradates are equivalent to the parent compound and EECs for all aquatic organisms will be generated using the

tota l toxic residues (TTR) approach. This approach was used to determine the environmental fate data parameters for modeling in conjunction with the Guidance for

Select ing Input Parameters in Modeling the Environmental Fate and Transport of

### 27 Pesticides , Version 2.1, October 22, 2009 and the draft Guidance for Modeling Pesticides Total Toxic Residues (TTR) May 20, 2009.

The environmental fate p roperties used for modeling the combined residues are

summarized in Table 10

.

Table 10 . PRZM/EXAMS Input Parameters for Cyantraniliprole

### 28 Input Parameter: Value: Comment: Source:

Scenario(s): Brassica Vegetables : CA Cole Crop

Bushberries: NY Grapes

Citrus:

FL Citrus

Cotton: CA, MS, NC Cotton

Cucurbits:

FL Cucumber Fruiting Vegetables: CA Pepper CA, FL, PA Tomato Leafy Vegetables:

CA Lettuce

Oil Seeds:

ND Canola

ND Wheat

Pome Fruit: NC, OR, PA Apple

CA Fruit

Potatoes:
ID, ME Potato Corm and Tuberous Vegetables:
ID, ME Potato Rapeseed, Mustard Seed:

ND Canola

ND Wheat

Stone Fruit: MI Cherry

GA Peaches

CA Fruit

Sunflower:

ND Canola

ND Wheat

Tree Nuts:

CA Almonds

GA Pecans Bulb Vegetables: CA, GA Onions

Flowerbeds and Groundcovers: CA, FL, MI, NJ, OR, TN Nursery

Trees:

OR Christmas Tree Turf, Golf Courses, Lawns, etc.: FL, PA Turf

Potted Ornamentals: CA, FL, MI, NJ, OR, TN Nursery representative scenarios for each use EFED Scenarios

Maximum Single Application Rate lbs a.i./acre (kg a.i./ha) Ranges from Table 5 : 0.016 (0.018) to 0.690 (0.775) See Table 5 for proposed rates. Proposed labels

Applications per Year Varies from 1 to 5, depending on crop and product ( Table 5 ) Label directions. Label specifies rates per crop. If there are multiple crops grown per year, yearly rates may be higher. Proposed labels

Application Interval (days) Varies from 5 to 30, depending on crop and product ( Table 5 ) Label directions Proposed labels

### 29 Input Parameter: Value: Comment: Source:

Date of Initial Application (scenario: day

- month) Varies ( Table 5 ) For most crops, the date of initial application

was calculated from the harvest date from the crop profile and the Pre

- Harvest Interval (PHI) and number and interval of applications from the proposed label. Where a pre

- harvest interval was not provided, a n interval of 1 day was assumed. Two weeks prior to crop emergence was assumed as the date of initial application for seed treatments. For ornamental and tree scenarios, an arbitrary date of April 15 was assumed as the date of initial application. Crop S cenarios and proposed labels

Application Method Aerial (foliar) Ground (foliar) Chemigation label directions Proposed labels

CAM Input 2 (foliar: aerial and ground) 1 (chemigation) 4 (seed treatment) (1) Soil applied, default incorporation depth, linearly decreasing with depth (2) linear foliar based on crop canopy (4) soil applied, user defined incorporation depth (seed treatment) US EPA, 2005

IPSCND Input Brassica Vegetables: 2

Bushberries: 3

Citrus: 3

Cotton: 1

Cucurbits: 3 Fruiting Vegetables: 3 Leafy Vegetables: 2

Oil Seeds: 1

Pome Fruit: 3

Potatoes: 2 Corm and Tuberous Vegetables: 2 Rapeseed, Mustard Seed: 1

Stone Fruit: 3

Sunflower: 1

Tree Nuts: 3 Bulb Vegetables: 2

Flowerbeds and Groundcovers: 3

Trees: 3

Turf: 1

Potted Ornamentals:3 ...remaining pesticide on foliage is (1) converted to surface application to the top soil layer, (2) completely removed after harvest, (3)

is retained as surface residue and continues to decay. This input only applies to foliar applications (C AM 2). US EPA, 2005

Spray Drift Fraction 0.05 (aerial) 0.01 (ground) 0 (chemigation, seed treatment) -- Input parameter guidance (USEPA, 2009a)

Application Efficiency 0.95 (aerial) 0.99 (ground) 1.0 (chemigation, seed treatment) -- Input parameter guidance (USEPA, 2009a)

Incorporation Depth Inches (cm) Potato: 2.0” (5.08 cm) Rapeseed: 0.5” (1.27 cm) Sunflower: 1.0” (2.54 cm) Seed treatment use info Proposed Labels

Molecular Mass (g/mol) 473.72

-- MRID 48119904

Vapor Pressure (torr) 3.85 x 10

- 17 20°C MRID 48122593

Henry’s Law Constant (atm

- m 3 /mol) 1.70 x 10
- 18 20°C MRID 48119907

Solubility in Water (mg/L) 14.2 R.O. water at 20°C MRID 48119901

### 30 Input Parameter: Value: Comment: Source:

Organic Carbon Partition Coefficient (K OC ) (L/kg OC ) 14 Lowest K

oc value among parent and degradates MRID 48120067

Aerobic Soil Metabolism

Half

- life (days) 1327 value represents the upper 90% confidence

limit on the mean value of total toxic residue (TTR) values (3 soils). MRID 48120045

Aerobic Aquatic

Metabolism Half

- life (days) 589 value represents the upper 90% confidence

limit on the mean value of total toxic residue (TTR) values. MRID 48120049

Anaerobic Aquatic

Metabolism Half

- life (days) 961 value represents the upper 90% confidence

limit on the mean value of total toxic residue (TTR) values (2 systems). MRID 48120071

MRID 48120081

Hydrolysis Half

- lives (days) 0 (stable) Half life could not be calculated because of the stability of combined residues MRID 48119905

Aqueous Photolysis

Half

- life (days) 88 value represents the upper 90% confidence

limit on the mean value of total toxic residue (TTR) values. MRID 48119906

Where the TTR approach was identified, half lives were recalculated to account for the parent including the identified residues of concern. Draft Guidance for Modeling Pesticides Total Toxic Residues (TTR) in addition to the NAFTA Guidance for Evaluating and Calcul ating Degradation Kinetics in Environmental Media were utiliz ed.



### The aquatic EECs for the various scenarios and application practices are listed in Tables

11 and 12 . See Appendix D for a representative output from PRZM/EXAMS. Peak surface water EECs ranged from 0.23 to 3 8 μg/L and peak pore water EECs ranged from

0.22 to 3 7 μg/L for application to the proposed cyantraniliprole uses.

Table 11

. C yantraniliprole Estimated Environmental Concentrations (EECs) for

Surface Water

Proposed Label

Use PRZM/EXAMS

Scenario (first app date) Method 1 Product Application Rate (interval between

applications) Peak

EEC
( 

### μg/L ) 21

- day

EEC
( 

### μg/L ) 60

- day

EEC
( 

### μg/L )

Brassica vegetables CA Cole Crop (Jan 30) C A 16901B CP

Insecticide 1 app at 0.4 lb a.i./acre 22.58 22.45 22.19

Brassica leafy vegetables CA Cole Crop (Feb 14) A

A 16901B CP

Insecticide 2 apps at 0.175 lb a.i./acre 1 app at 0.050 lb a.i./acre (7

- day interval) 21.01 20.89 20.66

G 17.03 16.94 16.75

Brassica leafy vegetables CA Cole Crop (Feb 18) A

Exirel 3 apps at 0.133 lb a.i./acre (5

- day interval) 16.90 16.81 16.64

G 12.83 12.77 12.65

Bushberries NY Grapes (Oct 2) A

Exirel 3 apps at 0.133 lb a.i./acre (5

- day interval) 13.28 13.24 13.17

G 8.71 8.69 8.64

Citrus FL Citrus (Dec 16) A

Exirel 3 apps at 0.133 lb a.i./acre (7

- day interval) 16.66 15.58 15.30

G 14.64 13.58 13.34

Citrus FL Citrus (Dec 30) C Verimark 1 app at 0.4 lb a.i./acre 11.01 10.13 9.98

### 31 Proposed Label

Use PRZM/EXAMS

Scenario (first app date) Method 1 Product Application Rate (interval between

applications) Peak

EEC
( 

### μg/L ) 21

- day

EEC
( 

### μg/L ) 60

- day

EEC
( 

### μg/L )

Cotton CA Cotton (Oct 21) A

Benevia 3 apps at 0.133 lb a.i./acre (7

- day interval) 9.21 9.16 8.98

G 6.11 6.09 5.96

MS Cotton (Sept 1) A 29.45 29.07 28.50

G 27.33 29.96 26.44

NC Cotton (Oct 11 ) A 37.97 37.78 37.42

G 35.58 35.40 35.06

Cucurbits FL Cucumber (Oct 31) A A 16901B CP

Insecticide 2 apps at 0.175 lb a.i./acre 1 app at 0.050 lb a.i./acre (5

- day interval) 33.01 32.66 31.82

G 31.79 31.38 30.57

Cucurbits FL Cucumber (Nov 29) C Verimark 2 apps at 0.130 lb a.i./acre (10

- day interval) 5.33 5.14 4.21

Cucurbits FL Cucumber (Dec 9) C A 16901B CP

Insecticide 1 app at 0.4 lb a.i./acre 9.66 9.56 7.91

Fruiting vegetables FL Peppers (Nov 20) A

A 16901B CP

Insecticide 2 apps at 0.175 lb a.i./acre 1 app at 0.050 lb a.i./acre (5

- day interval) 15.89 15.74 14.56

G 14.22 14.09 12.65

CA Tomato (Aug 21) A 15.91 15.70 15.50

G 13.20 12.86 12.70

FL Tomato (May 4) A 25.73 25.37 24.67

G 24.08 23.74 23.10

PA Tomato (Oct 4) A 28.14 28.07 27.95

G 24.87 24.81 24.71

Fruiting vegetables FL Peppers (Nov 25) C

Verimark 2 apps at 0.130 lb a.i./acre (5

- day interval) 5.03 4.98 4.38

CA Tomato (Aug 26) C 1.47 1.46 1.40

FL Tomato (May 9) C 10.17 10.04 9.78

PA Tomato (Oct 9) C 12.51 12.48 12.43

Fruiting vegetables FL Peppers (Nov 1) C

A 16901B CP

Insecticide 1 app at 0.4 lb a.i./acre 25.64 25.42 25.00

CA Tomato (Aug 2) C 0.28 0.27 0.27

FL Tomato (April 15) C 16.79 16.54 16.08

### 32 Proposed Label

Use PRZM/EXAMS

Scenario (first app date) Method 1 Product Application Rate (interval between

applications) Peak

EEC
( 

### μg/L ) 21

- day

EEC
( 

### μg/L ) 60

- day

EEC
( 

### μg/L )

PA Tomato (Sept 15) C 10.97 10.93 10.87

Leafy vegetables CA Lettuce (April 12) C A 16901B CP

Insecticide 1 app at 0.4 lb a.i./acre 16.04 15.95 15.30

Leafy vegetables CA Lettuce (April 21) A A 16901B CP

Insecticide 2 apps at 0.175 lb a.i./acre 1 app at 0.050 lb a.i./acre (7

- day interval) 14.09 14.02 13.87

G 10.37 10.32 10.22

Leafy vegetables (except B rassica ) CA Lettuce (May 1) A Exirel 3 apps at 0.133 lb a.i./acre (5

- day interval) 10.90 10.83 10.69

G 6.81 6.78 6.71

Oil seeds ND Canola (Aug 4) A

Benevia 3 apps at 0.133 lb a.i./acre (7

- day interval) 22.41 22.25 22.02

G 18.31 18.18 17.97

ND Wheat (July 15) A 25.47 25.35 25.24

G 21.54 21.49 21.40

Pome fruit CA Fruit (Oct 8) A

Exirel 3 apps at 0.133 lb a.i./acre (7

- day interval) 4.98 4.96 4.93

G 1.63 1.63 1.61

NC Apple (Oct 14) A 19.78 19.69 19.54

G 16.27 16.20 16.07

OR Apple (Sept 28) A 12.78 12.73 12.63

G 8.45 8.43 8.35

PA Apple (July 15) A 14.53 14.36 14.07

G 11.01 10.91 10.73

Potatoes ID Potato (May 18) S A17960A ST

and A17960B

ST 1 app at 0.690 lb a.i./acre 3 6.53 6.51 6.45

ME Potato (May 18) S 8.96 8.90 8.77

Potatoes ID Potato (May 18) S

Verimark 1 app at 0.176 lb a.i./acre 1.67 1.66 1.65

ME Potato (May 18) S 2.29 2.27 2.24

Corm and

tuberous vegetables ID Potato (Aug 29) A

Benevia 3 apps at 0.133 lb a.i./acre (5

- day interval) 19.26 19.14 18.98

G 14.52 14.43 14.32

ME Potato (Sept 18) A 25.49 25.43 25.33

G 20.54 20.49 20.41

Corm and

tuberous ID Potato (Sept 14) C A 16901B CP

Insecticide 1 app at 0.250 lb a.i./acre 6.90 6.88 6.85

### 33 Proposed Label

Use PRZM/EXAMS

Scenario (first app date) Method 1 Product Application Rate (interval between

applications) Peak

EEC
( 

### μg/L ) 21

- day

EEC
( 

### μg/L ) 60

- day

EEC
( 

### μg/L )

vegetables ME Potato (Oct 4) C 10.67 10.65 10.60

Rapeseed including canola varieties,

mustard seed ND Canola (May 2) S

Dermacor 1 app at 0.400 lb a.i./acre 19.82 19.72 19.61

ND Wheat (May 2) S 36.53 36.44 36.26

Stone fruit MI Cherry (July 4) A

Exirel 3 apps at 0.133 lb a.i./acre (7

- day interval) 19.10 18.98 18.74

G 14.33 14.23 14.07

GA Peaches (Aug 14) A 6.11 6.03 5.91

G 3.33 3.31 3.28

CA Fruit (July 15) A 6.30 6.01 5.90

G 3.40 3.11 3.07

Sunflower ND Canola (May 2) S A17960A ST

and A17960B

ST 1 app at 0.016 lb a.i./acre 2 0.45 0.45 0.45

ND Wheat (May 2) S 0.84 0.84 0.84

Tree nuts CA Almonds (Aug 25) A

Exirel 3 apps at 0.133 lb a.i./acre (7

- day interval) 11.02 10.97 10.87

G 8.48 8.44 8.35

GA Pecans (Sept 12) A 19.27 19.18 19.01

G 17.18 17.10 16.94

Bulb vegetables CA Onion (June 4) A

Benevia 3 apps at 0.133 lb a.i./acre (5

- day interval) 6.07 5.96 5.77

G 3.17 3.12 3.03

GA Onion (June 4) A 20.84 20.59 20.11

G 18.40 18.21 17.76

Flowerbeds and groundcovers CA Nursery (April 15)

G HGW86

T&O Insect

Control 2 apps at 0.208 lb a.i./acre (7

- day interval) 5.45 5.41 2.59

FL Nursery (April 15) 16.09 15.96 16.65

MI Nursery (April 15) 16.27 16.20 15.98

NJ Nursery (April 15) 14.09 14.03 13.84

OR Nursery (April 15) 4.25 4.22 4.18

### 34 Proposed Label

Use PRZM/EXAMS

Scenario (first app date) Method 1 Product Application Rate (interval between

applications) Peak

EEC
( 

### μg/L ) 21

- day

EEC
( 

### μg/L ) 60

- day

EEC
( 

### μg/L )

TN Nursery (April 15) 12.20 12.11 11.91

Ornamentals treated by

commercial and

consumer applicators CA Nursery (April 15)

G A 16901B

Residential 2 apps at 0.130 lb a.i./acre 4

(7

- day interval) 3.40 3.37 3.30

FL Nursery (April 15) 10.04 9.95 9.77

MI Nursery (April 15) 10.15 10.11 9.98

NJ Nursery (April 15) 8.79 8.75 8.64

OR Nursery (April 15) 2.65 2.64 2.61

TN Nursery (April 15) 7.61 7.56 7.43

Ornamental plants, fruit and nut trees (non

bearing) and forest seedlings grown in greenhouses, lath

and shade houses, containers, field

nurseries and interiorscapes CA Nursery (April 15)

G Mainspring 2 apps at 0.130 lb a.i./acre (14

- day interval) 3.45 3.42 3.33

FL Nursery (April 15) 6.79 6.73 6.58

MI Nursery (April 15) 10.24 10.19 10.11

NJ Nursery (April 15) 9.07 9.03 8.91

OR Nursery (April 15) 2.72 2.71 2.68

TN Nursery (April 15) 7.62 7.57 7.44

Ornamental plants, fruit and nut trees (non

bearing) and forest seedlings grown in greenhouses, lath

and shade houses, containers, field

nurseries and interiorscapes CA Nursery (April 15)

C Mainspring 2 apps at 0.130 lb a.i./acre (14

- day interval) 0.41 0.40 0.40

FL Nursery (April 15) 3.65 3.60 3.50

MI Nursery (April 15) 7.69 7.66 7.55

NJ Nursery (April 15) 5.92 5.87 5.82

OR Nursery (April 15) 1.49 1.49 1.47

TN Nursery (April 15) 6.94 6.88 6.75

Ornamental plants (exterior landscapes and

interior plantscapes CA Nursery (April 15)

G HGW86

T&O Insect

Control 1 app at 0.420 lb a.i./acre 5.94 5.91 5.84

FL Nursery (April 15) 10.20 10.12 9.90

MI Nursery (April 15) 16.26 16.17 16.03

NJ Nursery (April 15) 18.54 18.47 18.25

OR Nursery (April 15) 4.21 4.19 4.15

TN Nursery (April 15) 10.60 10.55 10.40

### 35 Proposed Label

Use PRZM/EXAMS

Scenario (first app date) Method 1 Product Application Rate (interval between

applications) Peak

EEC
( 

### μg/L ) 21

- day

EEC
( 

### μg/L ) 60

- day

EEC
( 

### μg/L )

Ornamental plants (exterior landscapes and

interior plantscapes CA Nursery (April 15)

C HGW86

T&O Insect

Control 1 app at 0.420 lb a.i./acre 1.28 1.27 1.26

FL Nursery (April 15) 6.31 6.25 6.11

MI Nursery (April 15) 13.19 13.15 13.02

NJ Nursery (April 15) 12.50 12.43 12.26

OR Nursery (April 15) 1.90 1.90 1.89

TN Nursery (April 15) 9.14 9.09 8.95

Trees (including

non

- bearin g fruit and nut trees), shrubs,

evergreens
, foliage plants, groundcovers, vines, interior plantscape plants OR Christmas

Trees (April 15) C HGW86 GH

& N Insect

Control 1 app at 0.420 lb a.i./acre 0.23 0.23 0.23

Trees (including

non

- bearing fruit and nut trees), shrubs,

evergreens, bedding plants, flowering plants, flowers, foliage plants, groundcovers, vines, interior plantscape plants, vegetable transplants (fruiting, leafy, tuberous, corm) OR Christmas

Trees (April 15) G HGW86 GH

& N Insect

Control 1 app at 0.420 lb a.i./acre 1.77 1.76 1.74

Turf , golf

courses, residential lawns,

commercial grounds, parks, playgrounds, athletic fields,

sod farms FL Turf (Feb 15)

G A 16901B

Turf 2 apps at 0.130 lb a.i./acre (30

- day interval) 1.39 1.37 1.35

CA Turf (April 15) 1.46 1.45 1.43

Grassy, weedy, mulched, or bare

soil areas in and

around greenhouses, nurseries, interior FL Turf (Feb 15)

G HGW86 GH

& N Insect

Control 1 app at 0.233 lb a.i./acre 1 app at 0.187 lb a.i./acre (30

- day interval) 2.21 2.19 2.15

CA Turf (April 15) 2.46 2.44 2.41

### 36 Proposed Label

Use PRZM/EXAMS

Scenario (first app date) Method 1 Product Application Rate (interval between

applications) Peak

EEC
( 

### μg/L ) 21

- day

EEC
( 

### μg/L ) 60

- day

EEC
( 

### μg/L )

plantscapes, lath

and shade house

, under trees and

shrubs that are being grown in

ground

Fly control bait GENEEC E HGW86 Fly

Control Bait 5 apps at 0.087 lb a.i./acre (7

- day interval) 23.67 23.49 23.16

Public health

insect control GENEEC E HGW86 SC

Insect Control 1 app at 0.420 lb a.i./acre 23.02 22.85 22.52

Potted

ornamentals CA Nursery (April 15)

C HGW86

GH&N Insect

Control 1 app at 0.500 lb a.i./acre 1.52 1.51 1.49

FL Nursery (April 15) 7.51 7.44 7.28

MI Nursery (April 15) 15.71 15.66 15.51

NJ Nursery (April 15) 14.89 14.80 14.60

OR Nursery (April 15) 2.27 2.26 2.24

TN Nursery (April 15) 10.88 18.82 10.65

Potted

ornamentals CA Nursery (April 15)

C Mainspring 2 apps at 0.130 lb a.i./acre (14

- day interval) 0.41 0.40 0.40

FL Nursery (April 15) 3.65 3.60 3.50

MI Nursery (April 15) 7.69 7.66 7.55

NJ Nursery (April 15) 5.92 5.87 5.82

OR Nursery (April 15) 1.49 1.49 1.47

TN Nursery (April 15) 6.94 6.88 6.75

1 A = foliar aerial application modeled as 95% application efficiency, 5% spray drift; G = foliar ground application modeled as 99% application efficiency, 1% sp ray drift; C = chemigation modeled as 100% application efficiency, 0% spray drift, E = Tier 1 GENEEC Model was utilized. S = Seed Treatment modeled as 100% application efficiency, 0% spray drift

2 Based on 0.00000044 lb ai/seed * 4 lb se ed/A * 9000 seeds/lb (USEPA 2011b). 3 Based on 0.00013 lb ai/lb potato * 5271 lb potato/A (T

- REX). 4 Based on communication with registrant.



### Table 12 . Cyantraniliprole Estimated Environmental Concentrations (EECs) for

Sediment Pore Water

Proposed

Label Use PRZM/EXAMS

Scenario (first app date) Method 1 Product Application Rate (interval between

applications) Peak

EEC
( 

### μg/L ) 21

- day

EEC
( 

### μg/L ) 60

- day

EEC
( 

### μg/L )

Brassica vegetables CA Cole Crop (Jan 30) C A 16901B CP

Insecticide 1 app at 0.4 lb a.i./acre 20.24 20.14 20.00

### 37 Proposed

Label Use PRZM/EXAMS

Scenario (first app date) Method 1 Product Application Rate (interval between

applications) Peak

EEC
( 

### μg/L ) 21

- day

EEC
( 

### μg/L ) 60

- day

EEC
( 

### μg/L )

Brassica leafy vegetables CA Cole Crop (Feb 14) A

A 16901B CP

Insecticide 2 apps at 0.175 lb a.i./acre 1 app at 0.050 lb a.i./acre (7

- day interval) 19.07 19.07 19.04

G 15.42 15.41 15.39

Brassica leafy vegetables CA Cole Crop (Feb 18) A

Exirel 3 apps at 0.133 lb a.i./acre (5

- day interval) 15.44 15.44 15.41

G 11.70 11.69 11.68

Bushberries NY Grapes (Oct 2) A

Exirel 3 apps at 0.133 lb a.i./acre (5

- day interval) 12.90 12.89 12.57

G 8.51 8.50 8.29

Citrus FL Citrus (Dec 16) A

Exirel 3 apps at 0.133 lb a.i./acre (7

- day interval) 13.23 13.23 13.19

G 11.46 11.46 11.43

Citrus FL Citrus (Dec 30) C Verimark 1 app at 0.4 lb a.i./acre 9.24 9.23 9.21

Cotton CA Cotton (Oct 21) A

Benevia 3 apps at 0.133 lb a.i./acre (7

- day interval) 8.33 8.33 8.32

G 5.45 5.45 5.44

MS Cotton (Sept 1) A 25.72 25.71 25.66

G 23.79 23.78 23.78

NC Cotton (Oct 11 ) A 34.01 33.76 33.67

G 31.80 31.47 31.36

Cucurbits FL Cucumber (Oct 31) A A 16901B CP

Insecticide 2 apps at 0.175 lb a.i./acre 1 app at 0.050 lb a.i./acre (5

- day interval) 25.54 25.45 25.32

G 24.32 24.23 24.10

Cucurbits FL Cucumber (Nov 29) C Verimark 2 apps at 0.130 lb a.i./acre (10

- day interval) 3.96 3.96 3.95

Cucurbits FL Cucumber (Dec 9) C A 16901B CP

Insecticide 1 app at 0.4 lb a.i./acre 7.78 7.74 7.71

Fruiting vegetables FL Peppers (Nov 20) A

A 16901B CP

Insecticide 2 apps at 0.175 lb a.i./acre 1 app at 0.050 lb a.i./acre (5

- day interval) 12.96 12.95 12.92

G 11.17 11.17 11.13

CA Tomato (Aug 21) A 14.41 14.40 14.34

G 11.75 11.74 11.69

FL Tomato (May 4) A 20.31 20.31 20.27

G 18.94 18.94 18.90

### 38 Proposed

Label Use PRZM/EXAMS

Scenario (first app date) Method 1 Product Application Rate (interval between

applications) Peak

EEC
( 

### μg/L ) 21

- day

EEC
( 

### μg/L ) 60

- day

EEC
( 

### μg/L )

PA Tomato (Oct 4) A 26.49 25.87 24.61

G 23.42 22.79 21.37

Fruiting vegetables FL Peppers (Nov 25) C

Verimark 2 apps at 0.130 lb a.i./acre (5

- day interval) 4.01 4.01 4.00

CA Tomato (Aug 26) C 1.29 1.28 1.28

FL Tomato (May 9) C 8.65 8.65 8.62

PA Tomato (Oct 9) C 11.05 10.72 10.58

Fruiting vegetables FL Peppers (Nov 1) C

A 16901B CP

Insecticide 1 app at 0.4 lb a.i./acre 24.60 23.83 20.69

CA Tomato (Aug 2) C 0.24 0.24 0.24

FL Tomato (April 15) C 12.51 12.51 12.48

PA Tomato (Sept 15) C 10.84 10.82 10.36

Leafy vegetables CA Lettuce (April 12) C A 16901B CP

Insecticide 1 app at 0.4 lb a.i./acre 14.03 14.00 13.97

Leafy vegetables CA Lettuce (April 21) A A 16901B CP

Insecticide 2 apps at 0.175 lb a.i./acre 1 app at 0.050 lb a.i./acre (7

- day interval) 13.03 13.02 13.00

G 9.38 9.37 9.36

Leafy vegetables (except

B rassica ) CA Lettuce (May 1) A

Exirel 3 apps at 0.133 lb a.i./acre (5

- day interval) 10.25 10.24 10.22

G 6.44 6.43 6.42

Oil seeds ND Canola (Aug 4) A

Benevia 3 apps at 0.133 lb a.i./acre (7

- day interval) 20.55 20.52 20.44

G 16.66 16.63 16.55

ND Wheat (July 15) A 24.65 24.58 24.34

G 20.67 20.67 20.48

Pome fruit CA Fruit (Oct 8) A

Exirel 3 apps at 0.133 lb a.i./acre (7

- day interval) 4.62 4.61 4.61

G 1.49 1.48 1.48

NC Apple (Oct 14) A 18.14 18.13 18.11

G 14.80 14.79 14.77

OR Apple (Sept 28) A 11.91 11.91 11.87

G 7.77 7.68 7.50

PA Apple A 12.98 12.98 12.98

### 39 Proposed

Label Use PRZM/EXAMS

Scenario (first app date) Method 1 Product Application Rate (interval between

applications) Peak

EEC
( 

### μg/L ) 21

- day

EEC
( 

### μg/L ) 60

- day

EEC
( 

### μg/L )

(July 15) G 9.85 9.85 9.83

Potatoes ID Potato (May 18) S A17960A ST

and A17960B

ST 1 app at 0.690 lb a.i./acre 3 5.80 5.80 5.79

ME Potato (May 18) S 8.21 8.20 8.19

Potatoes ID Potato (May 18) S

Verimark 1 app at 0.176 lb a.i./acre 1.48 1.48 1.48

ME Potato (May 18) S 2.10 2.09 2.09

Corm and

tuberous vegetables ID Potato (Aug 29) A

Benevia 3 apps at 0.133 lb a.i./acre (5

- day interval) 18.22 18.22 18.20

G 13.77 13.77 13.76

ME Potato (Sept 18) A 25.22 25.20 24.62

G 20.36 20.33 19.83

Corm and

tuberous vegetables ID Potato (Sept 14) C A 16901B CP

Insecticide 1 app at 0.250 lb a.i./acre 6.58 6.56 6.48

ME Potato (Oct 4) C 10.51 10.50 10.39

Rapeseed including

canola varieties,

mustard seed ND Canola (May 2) S

Dermacor 1 app at 0.400 lb a.i./acre 17.98 17.96 17.93

ND Wheat (May 2) S 36.74 36.63 36.44

Stone fruit MI Cherry (July 4) A

Exirel 3 apps at 0.133 lb a.i./acre (7

- day interval) 18.03 18.00 17.91

G 13.52 13.50 13.39

GA Peaches (Aug 14) A 5.41 5.41 5.39

G 3.32 3.28 3.00

CA Fruit (July 15) A 5.65 5.65 5.64

G 3.03 3.03 3.02

Sunflower ND Canola (May 2) S A17960A ST

and A17960B

ST 1 app at 0.016 lb a.i./acre 2 0.41 0.41 0.41

ND Wheat (May 2) S 0.85 0.84 0.84

Tree nuts CA Almonds (Aug 25) A

Exirel 3 apps at 0.133 lb a.i./acre (7

- day interval) 9.89 9.79 9.61

G 7.17 7.06 7.04

GA Pecans (Sept 12) A 17.44 17.20 16.80

G 15.41 15.19 14.68

### 40 Proposed

Label Use PRZM/EXAMS

Scenario (first app date) Method 1 Product Application Rate (interval between

applications) Peak

EEC
( 

### μg/L ) 21

- day

EEC
( 

### μg/L ) 60

- day

EEC
( 

### μg/L )

Bulb vegetables CA Onion (June 4) A

Benevia 3 apps at 0.133 lb a.i./acre (5

- day interval) 5.10 5.10 5.09

G 2.74 2.73 2.73

GA Onion (June 4) A 19.76 19.69 19.54

G 17.87 17.81 17.67

Flowerbeds

and groundcovers CA Nursery (April 15)

G HGW86

T&O Insect

Control 2 apps at 0.208 lb a.i./acre (7

- day interval) 5.22 5.22 5.20

FL Nursery (April 15) 16.24 16.09 15.82

MI Nursery (April 15) 14.62 14.61 14.58

NJ Nursery (April 15) 12.42 12.42 12.40

OR Nursery (April 15) 3.91 3.91 3.90

TN Nursery (April 15) 10.85 10.84 10.83

Ornamentals treated by

commercial

and consumer applicators CA Nursery (April 15)

G A 16901B

Residential 2 apps at 0.130 lb

a.i./acre 4

(7

- day interval) 3.25 3.25 3.25

FL Nursery (April 15) 10.13 10.04 9.87

MI Nursery (April 15) 9.12 9.11 9.10

NJ Nursery (April 15) 7.75 7.75 7.74

OR Nursery (April 15) 2.44 2.44 2.43

TN Nursery (April 15) 6.77 6.76 6.75

Ornamental plants, fruit

and nut trees (non

- bearing)

and forest seedlings grown in greenhouses,

lath and shade houses, containers,

field nurseries

and interiorscapes CA Nursery (April 15)

G Mainspring 2 apps at 0.130 lb a.i./acre (14

- day interval) 3.26 3.26 3.26

FL Nursery (April 15) 5.76 5.76 5.74

MI Nursery (April 15) 9.31 9.31 9.30

NJ Nursery (April 15) 8.01 8.01 8.00

OR Nursery (April 15) 2.47 2.47 2.46

TN Nursery (April 15) 6.65 6.65 6.63

Ornamental plants, fruit CA Nursery (April 15) C Mainspring 2 apps at 0.130 lb a.i./acre (14

- day interval) 0.41 0.41 0.41

### 41 Proposed

Label Use PRZM/EXAMS

Scenario (first app date) Method 1 Product Application Rate (interval between

applications) Peak

EEC
( 

### μg/L ) 21

- day

EEC
( 

### μg/L ) 60

- day

EEC
( 

### μg/L )

and nut trees (non

- bearing)

and forest seedlings grown in greenhouses,

lath and shade houses, containers,

field nurseries

and interiorscapes FL Nursery (April 15) 2.92 2.92 2.91

MI Nursery (April 15) 6.97 6.97 6.95

NJ Nursery (April 15) 5.29 5.29 5.28

OR Nursery (April 15) 1.34 1.34 1.34

TN Nursery (April 15) 5.88 5.86 5.82

Ornamental plants (exterior landscapes and

interior plantscapes CA Nursery (April 15)

G HGW86

T&O Insect

Control 1 app at 0.420 lb a.i./acre 5.49 5.49 5.47

FL Nursery (April 15) 8.74 8.68 8.56

MI Nursery (April 15) 14.82 14.82 14.79

NJ Nursery (April 15) 18.03 17.98 17.88

OR Nursery (April 15) 3.88 3.88 3.87

TN Nursery (April 15) 9.39 9.36 9.30

Ornamental plants (exterior landscapes and

interior plantscapes CA Nursery (April 15)

C HGW86

T&O Insect

Control 1 app at 0.420 lb a.i./acre 1.30 1.30 1.28

FL Nursery (April 15) 4.97 4.97 4.96

MI Nursery (April 15) 11.67 11.67 11.65

NJ Nursery (April 15) 11.59 11.59 11.58

OR Nursery (April 15) 1.90 1.89 1.88

TN Nursery (April 15) 7.87 7.84 7.79

Trees (including

non

- bearin g fruit and nut trees), shrubs,

evergreens
, foliage plants, groundcovers, vines, interior plantscape plants OR Christmas

Trees (April 15) C HGW86 GH

& N Insect

Control 1 app at 0.420 lb a.i./acre 0.22 0.22 0.22

Trees (including

non

- bearing

fruit and nut OR Christmas

Trees (April 15) G HGW86 GH

& N Insect

Control 1 app at 0.420 lb a.i./acre 1.61 1.61 1.61

### 42 Proposed

Label Use PRZM/EXAMS

Scenario (first app date) Method 1 Product Application Rate (interval between

applications) Peak

EEC
( 

### μg/L ) 21

- day

EEC
( 

### μg/L ) 60

- day

EEC
( 

### μg/L )

trees), shrubs,

evergreens, bedding plants, flowering plants, flowers, foliage plants, groundcovers, vines, interior plantscape plants, vegetable transplants (fruiting, leafy, tuberous, corm) Turf , golf

courses, residential lawns,

commercial grounds, parks, playgrounds, athletic fields,

sod farms FL Turf (Feb 15)

G A 16901B

Turf 2 apps at 0.130 lb a.i./acre (30

- day interval) 1.31 1.30 1.29

CA Turf (April 15) 1.37 1.37 1.37

Grassy, weedy, mulched, or

bare soil areas

in and around greenhouses, nurseries,

interior plantscapes,

lath and shade

house , under

trees and

shrubs that are being grown

in

- ground FL Turf (Feb 15)

G HGW86 GH

& N Insect

Control 1 app at 0.233 lb a.i./acre 1 app at 0.187 lb a.i./acre (30

- day interval) 1.98 1.97 1.96

CA Turf (April 15) 2.27 2.27 2.27

Fly control bait GENEEC E HGW86 Fly

Control Bait 5 apps at 0.087 lb a.i./acre (7

- day interval) 23.67 23.49 23.16

Public health

insect control GENEEC E HGW86 SC

Insect Control 1 app at 0.420 lb a.i./acre 23.02 22.85 22.52

Potted

ornamentals CA Nursery (April 15)

C HGW86

GH&N Insect

Control 1 app at 0.500 lb a.i./acre 1.55 1.54 1.53

FL Nursery (April 15) 5.92 5.92 5.90

MI Nursery (April 15) 13.90 13.89 13.87

NJ Nursery (April 15) 13.81 13.80 13.78

### 43 Proposed

Label Use PRZM/EXAMS

Scenario (first app date) Method 1 Product Application Rate (interval between

applications) Peak

EEC
( 

### μg/L ) 21

- day

EEC
( 

### μg/L ) 60

- day

EEC
( 

### μg/L )

OR Nursery (April 15) 2.26 2.25 2.24

TN Nursery (April 15) 9.37 9.34 9.27

Potted

ornamentals CA Nursery (April 15)

C Mainspring 2 apps at 0.130 lb a.i./acre (14

- day interval) 0.41 0.41 0.41

FL Nursery (April 15) 2.92 2.92 2.91

MI Nursery (April 15) 6.97 6.97 6.95

NJ Nursery (April 15) 5.29 5.29 5.28

OR Nursery (April 15) 1.34 1.34 1.34

TN Nursery (April 15) 5.88 5.86 5.82

1 A = foliar aerial application modeled as 95% application efficiency, 5% spray drift; G = foliar ground application modeled as 99% application efficiency, 1% spray drift; C = chemigation modeled as 100% application efficiency, 0% spray drift, E = Tier 1 GEN EEC Model was utilized. S = Seed Treatment modeled as 100% application efficiency, 0% spray drift

2 Based on 0.00000044 lb ai/seed * 4 lb seed/A * 9000 see ds/lb (USEPA 2011b).

3 Based on 0.00013 lb ai/lb potato * 5271 lb potato/A (T

- REX).

4 Based on communication with registrant.



### b. Aquatic Exposure Monitoring and Field Data

Cyantraniliprole is a ne w chemical, for which no monitoring data are available. The California Department of Pesticide Regulation (CDPR) surface water database ( http://www.cdpr.ca.gov/docs/emon/surfwtr/surfcont.htm and USGS NAWQA surface and ground water database ( http://infotrek.er.usgs.gov/apex/f?p=136:1:0::NO :::) were

search ed for available monitoring data , but none were located. Also, no monitoring data on the degradates were found.

3. Measures of Terrestrial Exposure

a. Terrestrial Exposure Modeling

T

- REX is used to model exposures to birds, mammals, and terrestrial invertebrates. The application method for the proposed uses of cyantraniliprole include foliar spray (ground and aerial), micro sprinkler chemigation, drip chemi gati on, seed treatments, soil drench/injection, bark spray, spot/crack/crevice (public health use) , and granular bait ( Table 13 )

. The t errestrial EECs for cyan traniliprole are derived using the maximum

a nnual application rate (Tables 14

– 16 ) . The default 35

- day foliar half

- life value was used for modeling EECs on terrestrial food items because chemical

- specific foliar half

life data were not available . A n example of the output is contained in Appendix E

.

### 44 The use of cyantraniliprole as a f ly bait is inclu ded in Table 13 ; however, because the acute toxicity endpoints for mammals and birds were non

- definitive, the typical LD 50 

### /ft 2


### analysis could not be performed. See the Risk Description section for further discussion

on risks to birds and mammals.

Table 1 3 . T

- REX M odeling for F oliar, Bark S pray , Seed T reatment , and G ranular

A pplications

Use Maximum
Application
Rate (lb ai/A) Number of
Applications
(Interval between
Applications,
days)

Brassica leafy vegetables , leafy vegetables 0.175 2 at 0.175

1 at 0.05

(7 days)

Brassica leafy vegetables, bushberries, leafy vegetables
(except brassica), corm and tuberous vegetables, bulb
vegetables 0.133 3

(5 days)

Citrus, cotton, oil seeds, pome fruit, stone fruit, tree nuts 0.133 3

(7 days)

Cucurbits, fruiting vegetables 0.175 2 at 0.175

1 at 0.05

(5 days)

Potatoes (seed treatment) 0.69 1

Potatoes (seed treatment) 0.176 1
Rapeseed including canola varieties, mustard seed 0.4 1

Sunflower (seed treatment) 0.016 1

Flowerbeds and groundcovers 0.208 2

(7 days)

Ornamentals treated by commercial and consumer
applicators 0.13 2

(7 days)

Ornamental plants, fruit and nut trees (non

- bearing) and
forest seedlings grown in greenhouses, lath and shade
houses, containers, field nurseries and interiorscapes 0.26 1 at 0.26

1 at 0.16

(14 days)
Ornamental plants (exterior landscapes and interior
plantscapes ), trees (including non

- bearing fruit and nut
trees) shrubs, evergreens, bedding plants, flowering
plants, flowers, foliage plants, groundcovers, vines,
interior plantscape plants, vegetable transplants (fruiting,
leafy, tuberous, corm) , public health insect control 0.42 1

### 45 Use Maximum
Application
Rate (lb ai/A) Number of
Applications
(Interval between
Applications,
days)

Turf, golf courses, residential lawns, commercial grounds,
parks, playgrounds, athletic fields, sod farms, grassy,
weedy, mulched, or bare soil areas in and around
greenhouses, nurseries, interior plantscapes, lath and

shade house , under trees and shrubs t hat are being grown

in

- ground 0.26 1 at 0.26

1 at 0.16

(30 days)

Fly control bait (granular) 0.087 5

(7 days)



### Table 1 4

. Avian F ol iar, Bark S pray, and Seed T reatment Upper

- Bound EEC

V alues

Feeding Category Dietary

- based
EECs (mg/kg

food item) Dose

- based EECs (mg/kg

- bw)

Small
(20 g) Medium
(100 g) Large
(1000 g)

Brassica leafy vegetables, leafy vegetables
2 apps at 0.175 lb ai/A and 1 app at 0.05 lb ai/A (7 days)

Short grass 80.39 91.56 52.21 23.38 Tall grass 36.85 41.96 23.93 10.71 Broadleaf plants 45.22 51.50 29.37 13.15 Fruits/pods 5.02 5.72 3.26 1.46 Arthropods 31.49 35.86 20.45 9.16

Seeds 5.02 1.27 0.73 0.32

Brassica leafy vegetables, bushberries, leafy vegetables (except brassica), corm and tuberous vegetables,

bulb vegetables
3 at 0.133 lb ai/A (5 days)

Short grass 87.02 99.10 56.51 25.30 Tall grass 39.88 45.42 25.90 11.60 Broadleaf plants 48.95 55.75 31.79 14.23 Fruits/pods 5.44 6.19 3.53 1.58 Arthropods 34.08 38.82 22.13 9.91

Seeds 5.44 1.38 0.78 0.35
Citrus, cotton, oil seeds, pome fruit, stone fruit, tree nuts
3 apps at 0.133 lb ai/A (7 days)

Short grass 83.90 95.55 54.49 24.39 Tall grass 38.45 43.79 24.97 11.18 Broadleaf plants 47.19 53.75 30.65 13.72 Fruits/pods 5.24 5.97 3.41 1.52 Arthropods 32.86 37.42 21.34 9.55

### 46 Feeding Category Dietary

- based
EECs (mg/kg

food item) Dose

- based EECs (mg/kg

- bw)

Small
(20 g) Medium
(100 g) Large
(1000 g)

Seeds 5.24 1.33 0.76 0.34
Cucurbits, fruiting vegetables
2 apps at 0.175 lb ai/A and 1 app at 0.05 lb ai/A (5 days)

Short grass 84.49 96.23 54.87 24.57 Tall grass 38.73 44.11 25.15 11.26 Broadleaf plants 47.53 54.13 30.87 13.82 Fruits/pods 5.28 6.01 3.43 1.54 Arthropods 33.09 37.69 21.49 9.62

Seeds 5.28 1.34 0.76 0.34

Potatoes (seed treatment)

1 at 0.69 lb ai/A

Seeds

- 113.65 64.81 29.01

Potatoes (seed treatment)

1 app at 0.176 lb ai/A

Seeds

- 28.99 16.53 7.40

Rapeseed including canola varieties, m ustard seed (seed treatment)
1 app at 0.4 lb ai/A

Seeds

- 65.88 37.57 16.82

Sunflower (seed treatment)
1 app at 0.016 lb ai/A

Seeds

- 2.64 1.50 0.67

Flowerbeds and groundcovers
2 apps at 0.208 lb ai/A (7 days)

Short grass 93.38 106.35 60.64 27.15 Tall grass 42.80 48.74 27.80 12.44 Broadleaf plants 52.53 59.82 34.11 15.27 Fruits/pods 5.84 6.65 3.79 1.70 Arthropods 36.57 41.65 23.75 10.63

Seeds 5.84 1.48 0.84 0.38
Ornamentals treated by commercial and consumer applicators

2 apps at 0.13 lb ai/A (7 days)

Short grass 58.36 66.47 37.90 16.97 Tall grass 26.75 30.46 17.37 7.78 Broadleaf plants 32.83 37.39 21.32 9.55 Fruits/pods 3.65 4.15 2.37 1.06 Arthropods 22.86 26.03 14.85 6.65

Seeds 3.65 0.92 0.53 0.24

Ornamental plants, fruit and nut trees (non

- bearing) and forest seedlings grown in greenhouses, lath and
shade houses, containers, field nurseries and interiorscapes

1 app at 0.26 lb ai/A and 1 app at 0.16 lb ai/A (14 days)

Short grass 85.69 97.59 55.65 24.92 Tall grass 39.27 44.73 25.51 11.42

### 47 Feeding Category Dietary

- based
EECs (mg/kg

food item) Dose

- based EECs (mg/kg

- bw)

Small
(20 g) Medium
(100 g) Large
(1000 g)

Broadleaf plants 48.20 54.90 31.30 14.02 Fruits/pods 5.36 6.10 3.48 1.56 Arthropods 33.56 38.22 21.80 9.76

Seeds 5.36 1.36 0.77 0.35
Ornamental plants (exterior landscapes and interior plantscapes), trees (including non

- bearing fruit and nut
trees) shrubs, evergreens, bedding plants, flowering plants, flowers, foliage plants, groundcovers, vines,
interior plantscape plants, vegetable transplants (fruiting, leafy, tuberous, corm), public health insect contro l

1 app at 0.42 lb ai/A

Short grass 100.80 114.80 65.46 29.31 Tall grass 46.20 52.62 30.00 13.43 Broadleaf plants 56.70 64.58 36.82 16.49 Fruits/pods 6.30 7.18 4.09 1.83 Arthropods 39.48 44.96 25.64 11.48

Seeds 6.30 1.59 0.91 0.41

Turf, golf courses, residential lawns, commercial grounds, parks, playgrounds, athletic fields, sod farms,
grassy, weedy, mulched, or bare soil areas in and around greenhouses, nurseries, interior plantscapes, lath

and shade houses , under trees and shrubs that are being grown in

- ground

1 app at 0.26 lb ai/A and 1 app at 0.16 lb ai/A (30 days)

Short grass 72.85 82.97 47.31 21.18 Tall grass 33.39 38.03 21.68 9.71 Broadleaf plants 40.98 46.67 26.61 11.91 Fruits/pods 4.55 5.19 2.96 1.32 Arthropods 28.53 32.50 18.53 8.30

Seeds 4.55 1.15 0.66 0.29



### Table 15

. Ma mmalian Foliar, Bark S pray, and Seed T reatment Upper

- Bound EEC

V alues

Feeding Category Dietary

- based
EECs (mg/kg

food item) Dose

- based EECs (mg/kg

- bw)

Small
(15 g) Medium
(135 g) Large
(1000 g)

Brassica leafy vegetables, leafy vegetables

2 apps at 0.175 lb ai/A and 1 app at 0.05 lb ai/A (7 days)

Short grass 80.39 76.65 52.97 12.28 Tall grass 36.85 35.13 24.28 5.63 Broadleaf plants 45.22 43.11 29.80 6.91 Fruits/pods 5.02 4.79 3.31 0.77 Arthropods 31.49 30.02 20.75 4.81

Seeds 5.02 1.06 0.74 0.17

Brassica leafy vegetables, bushberries, leafy vegetables (except brassica), corm and tuberous vegetables,
bulb vegetables

3 apps at 0.133 lb ai/A (5 days)

Short grass 87.02 82.96 57.34 13.29

### 48 Feeding Category Dietary

- based
EECs (mg/kg

food item) Dose

- based EECs (mg/kg

- bw)

Small
(15 g) Medium
(135 g) Large
(1000 g)

Tall grass 39.88 38.02 26.28 6.09 Broadleaf plants 48.95 46.67 32.25 7.48 Fruits/pods 5.44 5.19 3.58 0.83 Arthropods 34.08 32.49 22.46 5.21

Seeds 5.44 1.15 0.80 0.18
Citrus, cotton, oil seeds, pome fruit, stone fruit, tree nuts
3 apps at 0.133 lb ai/ A (7 days)

Short grass 83.90 79.99 55.28 12.82 Tall grass 38.45 36.66 25.34 5.87 Broadleaf plants 47.19 44.99 31.10 7.21 Fruits/pods 5.24 5.00 3.46 0.80 Arthropods 32.86 31.33 21.65 5.02

Seeds 5.24 1.11 0.77 0.18
Cucurbits, fruiting vegetables

2 apps at 0.175 lb ai/A and 1 app at 0.05 lb ai/A (5 days)

Short grass 84.49 80.56 55.68 12.91 Tall grass 38.73 36.92 25.52 5.92 Broadleaf plants 47.53 45.31 31.32 7.26 Fruits/pods 5.28 5.03 3.48 0.81 Arthropods 33.09 31.55 21.81 5.06

Seeds 5.28 1.12 0.77 0.18

Potatoes (seed treatment)
1 app at 0.69 lb ai/A

Seeds

- 95.14 65.75 15.25

Potatoes (seed treatment)

1 app at 0.176 lb ai/A

Seeds

- 24.27 16.77 3.89

Rapeseed including canola varieties, mustard seed (seed treatment)
1 app at 0.4 lb ai/A

Seeds

- 55.15 38.12 8.84

Sunflower (seed treatment)
1 app at 0.016 lb ai/A

Seeds

- 2.21 1.52 0.35

Flowerbeds and groundcovers
2 apps at 0.208 lb ai/A (7 days)

Short grass 93.38 89.03 61.53 14.27 Tall grass 42.80 40.80 28.20 6.54 Broadleaf plants 52.53 50.08 34.61 8.02 Fruits/pods 5.84 5.56 3.85 0.89 Arthropods 36.57 34.87 24.10 5.59

Seeds 5.84 1.24 0.85 0.20
Ornamentals treated by commercial and consumer applicators

### 49 Feeding Category Dietary

- based
EECs (mg/kg

food item) Dose

- based EECs (mg/kg

- bw)

Small
(15 g) Medium
(135 g) Large
(1000 g)

2 apps at 0.13 lb ai/A (7 days)

Short grass 58.36 55.64 38.46 8.92

Tall grass 26.75 25.50 17.63 4.09 Broadleaf plants 32.83 31.30 21.63 5.02 Fruits/pods 3.65 3.48 2.40 0.56 Arthropods 22.86 21.79 15.06 3.49

Seeds 3.65 0.77 0.53 0.12

Ornamental plants, fruit and nut trees (non

- bearing) and forest seedlings grown in greenhouses, lath and
shade houses, containers, field nurseries and interiorscapes
1 app at 0.26 lb ai/A and 1 app at 0.16 lb ai/A (14 days)

Short grass 85.69 81.70 56.47 13.09 Tall grass 39.27 37.45 25.88 6.00 Broadleaf plants 48.20 45.96 31.76 7.36 Fruits/pods 5.36 5.11 3.53 0.82 Arthropods 33.56 32.00 22.12 5.13

Seeds 5.36 1.13 0.78 0.18
Ornamental plants (exterior landscapes and interior plantscapes), trees (including non

- bearing fruit and nut

trees), shrubs, evergreens, bedding plants, flowering plants, flowers, foliage plants, groundcovers, vines,
interior plantscape plants, vegetable transplants (fruiting, leafy, tuberous, corm), public health insect control
1 app at 0.42 lb ai/A

Short grass 100.80 96.11 66.42 15.40 Tall grass 46.20 44.05 30.44 7.06 Broadleaf plants 56.70 54.06 37.36 8.66 Fruits/pods 6.30 6.01 4.15 0.96 Arthropods 39.48 37.64 26.02 6.03

Seeds 6.30 1.33 0.92 0.21

Turf, golf courses, residential lawns, commercial grounds, parks, playgrounds, athletic fields, sod farms,
grassy, weedy, mulched, or bare soil areas in and around greenhouses, nurseries, interior plantscapes, lath

and shade houses , under trees and shrubs that are being grown in

- ground
1 app at 0.26 lb ai/A and 1 app at 0.16 lb ai/A (7 days)

Short grass 92.72 88.40 61.10 14.17 Tall grass 42.50 40.52 28.00 6.49 Broadleaf plants 52.16 49.73 34.37 7.97 Fruits/pods 5.80 5.53 3.82 0.89 Arthropods 36.32 34.62 23.93 5.55

Seeds 5.80 1.23 0.85 0.20



### For insects, only two screening level EECs are calculated. The tall grass EEC represents the exposure through dietary intake whereas the arthropod EEC represents exposure through contact ( Table 16 ) (USEPA 2012b)

. Given that honeybee larval toxicity data were not available, only cyantraniliprole doses for adult bees are considered.

### 50 Table 16

. Adult Insect F ol iar Spray, Bark S pray, and G ranular Screening Level
Upper

- Bound EEC V alues

Use EEC (based on tall grass) (mg/kg

- diet) (dose in μg

ai/bee * ) EEC (based on arthropod) (mg/kg

- diet) (dose in μg ai/bee ** )
Brassica leafy vegetables, leafy vegetables 2 apps at 0.175 lb ai/A and 1 app at 0.05 lb ai/A (7 days) 36.85 (10.76) 16.45 1 (2.11)

Brassica leafy vegetables, bushberries, leafy vegetables (except brassica), corm and tuberous vegetables, bulb vegetables 3 apps at 0.133 lb ai/A (5 days) 39.88 (11.64) 34.08 (4.36)

Citrus, cotton, oil seeds, pome fruit, stone fruit, tree

nuts 3 apps at 0.133 lb ai/A (7 days) 38.45 (11.23) 12.50 2 (1.6)

Cucurbits, fruiting vegetables 2 apps at 0.175 lb ai/A and 1 app at 0.05 lb ai/A (5 days) 38.73 (11.31) 33.09 (4.24)

Flowerbeds and groundcovers 2 apps at 0.208 lb ai/A (7 days) 42.80 (12.50) 19.55 3 (2.50)

Ornamentals treated by commercial and consumer applicators 2 apps at 0.13 lb ai/A (7 days) 26.75 (7.81) 12.22 4 (1.56)

Ornamental plants, fruit and nut trees (non

- bearing) and forest seedlings grown in greenhouses, lath and shade houses, containers, field nurseries and interiorscapes 1 app at 0.26 lb ai/A and 1 app at 0.16 lb ai/A (14 days) 39.27 (11.47) 24.44 5 (3.13)

Ornamental plants (exterior landscapes and interior plantscapes), trees (including non

- bearing fruit and nut trees), shrubs, evergreens, bedding plants, flowering plants, flowers, foliage plants, groundcovers, vines, interior plantscape plants, vegetable transplants (fruiting, leafy, tuberous, corm), public health insect control 1 app at 0.42 lb ai/A 46.20 (13.49) 39.48 (5.05)

Turf, golf courses, residential lawns, commercial grounds, parks, playgrounds, athletic fields, sod farms, grassy, weedy, mulched, or bare soil areas in and around greenhouses, nurseries, interior plantscapes, lath and shade houses , under trees and shrubs that are being grown in

- ground 1 app at 0.26 lb ai/A and 1 app at 0.16 lb ai/A (30 days) 42.50 (12.41) 24.44 5 (3.13)

Fly control bait (granular) 5 apps at 0.087 lb ai/A (7 days) 36.96 (10.79) 8.18 6 (3.01)

*Conversion made by multiplying EEC by food consumption rate of adult bee (0.292 g/day) **Conversion made by multiplying EEC by body weight of adult bee (0.128 g)

1 Based on single app of 0.175 lb ai/A because application interval is >5 days

2 Based on single app of 0.133 lb ai/A because application interval is >5 days

3 Based on single app of 0.208 lb ai/A because application interval is >5 days

4 Based on single app of 0.13 lb ai/A because application interval is >5 days

### 51 Use EEC (based on tall grass) (mg/kg

- diet) (dose in μg

ai/bee * ) EEC (based on arthropod) (mg/kg

- diet) (dose in μg ai/bee ** )

5 Based on single app of 0.26 lb ai/A because application interval is >5 days

6 Based on single app of 0.087 lb ai/A because application interval is >5 days



### EEC Estimates for Soil Injection, Soil Drench, and Drip Irrigation (Birds and Mammals)

T

- REX could not be used to calculate EECs for soil injection, soil drench , and drip irrigation . T

- REX assumes that the chemical is applied over the tops of the plants and that terrestrial organisms are exposed to the chemical via the residues left on plant parts. The residues will degrade over time as they are exposed to environmental conditions ; the degradation rate may not be the same for systemic chemicals distributed within the plant

. For injections and drenches, cyantraniliprole is taken up into the plant via the roots. Terrestrial organisms can still be exposed to cyantraniliprole through eating leaves or

other plant parts, but the chemical is contained within the vegetation (systemic) rather than on the vegetation’s surface. Therefore, different methods were employed to estimate

the concentrations of cyantraniliprole in plants, based on the application method.

Soil Injection/ Soil Drench /Drip Irrigation and Woody Potted Ornamental Drench Leaf

Biomass Estimates

An EEC is the concentration of cyantraniliprole that is expected to be present in a unit of food. Therefore, to calculate an EEC, it is necessary to determine the biomass of the food

item and the amount of cyantraniliprole it is expected to contain.

For soil injection/ soil drenches, drip irrigation

, and drenches of woody potted ornamental plants , it is assumed that cyantraniliprole will accumulate in the leaves of the plant (a surrogate for other non

- woody food items

, such as fruit). Both hardwoods and softwoods

were considered in this scenario. L eaf biomass (dry weight) for hardwoods and softwoods were estimated using general hardwood and softwood leaf biomass equations

from Jenkins et al . (2003). Table 17 presents the biomass estimates for hardwoods and

softwoods. See Appendix F for the calcula tions.

Table 1 7 . Summary of Hardwood and Softwood Leaf Biomass Wet W eights

6

- Inch DBH (kg) 1

- Inch DBH (kg)

Hardwood (wet weight) 21.44 0.95

Softwood (wet weight) 47 2.3

DBH = diameter at breast height



### U sing the biomass information in Table 1 7

, EECs can be calculated for soil injection/ soil drench, and drench applications to woody potted ornamental ( Table 1 8 )

. See Appendix F for the complete calculations.

### 52 Table 18 . Summary of Mammalian and Avian EECs for Soil I njection/ Soil Drench,

P otted Ornamental D rench, and Agricultural Drip I rrigation

Bird and Mammal Mammal

Dietary (mg ai/kg

- plant) Acute Dose (mg ai/kg

- bw) 15 g 35 g 1000g
Soil injection/drench

hardwood 148 141 100 22

Soil injection/drench

hardwood 254 241 168 38

Soil drench (citrus) 233 221 154 35 Soil injection/drench

softwood 68 65 45 10

Soil injection/d rench

s oftwood 116 110 77 17

Potted non

- woody

ornamental d rench 4.6 4 3 0.7

Potted non

- woody

ornamental d rench 9 9 6 1

Drip irrigation (brassica vegetables) 64 61 42 10

Drip irrigation (cucurbits) 636 604 420 95

Drip irrigation (fruiting vegetables) 182 173 120 27

Drip irrigation (leafy vegetables 54 51 36 8

Drip irrigation (corm and tuberous vegetables) 64 61 42 10



### EEC Estimates for Soil Injection, Soil Drench, and Drip Irrigatio n (Terrestrial

Invertebrates )

The method outlined in USEPA 2012 b for estimating screening level pollen/nectar concentrations for soil treatments was used to develop EECs for the relevant cyantraniliprole uses. The model predicts the concentration of pesticide that is expected to be present in the stem of a plant; this is used a s a surrogate for pollen/nectar. The original equation was developed by Briggs et al . (1982 and 1983) and was modified by Ryan et al . (1988) and EPA to represent an upper

- bound estimate (95% transpiration

stream concentration factors

– TSCF).

SCF ’ = C stem 

### = [10 (0.95*LogKow

– 2.05) 

### ] * TSCF * [ ρ ]

C soil 

### Ө + ρ + K 0c 

### + f

oc



### Where: SCF’ = stem concentration factor based on uptake from soil

Cstem = concentration in stems ( μ g a.i./g plant) Csoil = concentration in soil ( μ g a.i./g soil) (derived from application rate) foc = fraction of organic carbon in soil

### 53 θ = soil

‐ water content by volume (cm3/cm3) ρ = soil bulk density (g

‐ dw/cm3)

K
oc 

### = soil organic carbon

‐ water partitioning coefficient (cm 3 

### /g

oc 

### or L/k goc 

### )

For cyantraniliprole

, Log K
ow 

### =1.94; K

oc 

### =241; and the adjusted 95% TSCF = 0.875 (USEPA 2012 b ). SCF’ was calculated to be 0.026

Consequently, the following EECs were derived for t he soil application scenarios (Table

19 ).

Table 19

. Screening Level Pollen/N ecta r EECs for Soil Application Scenarios (Terrestrial Invertebrates )

Use Dietary EEC (mg ai/kg

- food) (dose in μg ai/bee)*

Ornamental trees and potted ornamentals (soil injectio n/drench)

0.26 lb ai/A 0.007 (0.002)

Ornamental trees (soil injection/drench)

0.42 lb ai/A 0.011 (0.003)

Potted ornamentals (drench)

0.5 lb ai/A 0.013 (0.004)

Citrus (soil drench)

0.391 lb ai/A 0.0102 (0.003)

Brassica vegetables, cucurbits, leafy vegetables, fruiting vegetables, corm and tuberous vegetables (drip irrigation)

0.4 lb ai/A 0.0104 (0.003)

**Conversion made by multiplying EEC by food consumption rate of adult bee (0.292 g/day)



### EEC Estimates for S eed Treatments (Terrestrial Invertebrates )

Based on the EPPO 2010, a screening concentration of 1 mg ai/kg of pollen and nectar is used for the EEC for all seed treatments, regardless of application rate (USEPA 2012b). When converting to the adult bee nectar/pollen consumption rate , the equivalent dose for risk quotient calculation is 0.292 μg ai/bee.

EEC Estimates for Terrestrial Plants TerrPlant estimates potential exposure from a single application using d efault assumptions for runoff (2 % given solubility is 14.2 ppm) and spray drift (1% given a ground applic ation or 5% given an aerial application of a liquid formulation) ( Table 20 ).

See Appendix G for more information.

Table 2 0

. EECs on Plants Following Label

- Specified Applications of
Cyantraniliprole

Description Equation EEC (lb ai/A)

Brassica vegetables (soil)

### 54 Description Equation EEC (lb ai/A)

1 app at 0.35 lb ai/A

Runoff to dry areas (A/I)*R 0.007

Runoff to semi

- aquatic areas (A/I)*R*10 0.07 Spray drift A*D 0.0035 Total for dry areas ((A/I)*R)+(A*D) 0.0105

Total for semi

- aquatic areas ((A/I)*R*10)+(A*D) 0.0735
Brassica leafy vegetables, cucurbits, fruiting vegetables, leafy vegetables, (aerial spray)
1 app at 0.175 lb ai/A

Runoff to dry areas (A/I)*R 0.0035

Runoff to semi

- aquatic areas (A/I)*R*10 0.035 Spray drift A*D 0.00875

Total for dry areas ((A/I)*R)+(A*D) 0.01225

Total for semi

- aquatic areas ((A/I)*R*10)+(A*D) 0.04375
Brassica leafy vegetables, cucurbits, fruiting vegetables, leafy vegetables, (ground spray)
1 app at 0.175 lb ai/A

Runoff to dry areas (A/I)*R 0.0035

Runoff to semi

- aquatic areas (A/I)*R*10 0.035 Spray drift A*D 0.00175 Total for dry areas ((A/I)*R)+(A*D) 0.00525

Total for semi

- aquatic areas ((A/I)*R*10)+(A*D) 0.03675

Brassica leafy vegetables, bushberries, cotton, leafy vegetables (except brassica), oil seeds, pome fruit,
corm and tuberous vegetables, stone fruit, tree nuts, bulb vegetables, (aerial spray)
1 app at 0.133 lb ai/A

Runoff to dry areas (A/I)*R 0.00266

Runoff to semi

- aquatic areas (A/I)*R*10 0.0266 Spray drift A*D 0.00665 Total for dry areas ((A/I)*R)+(A*D) 0.00931

Total for semi

- aquatic areas ((A/I)*R*10)+(A*D) 0.03325
Brassica leafy vegetables, bushberries, citrus, cotton, leafy vegetables (except brassica), oil seeds, pome fruit, corm and tuberous vegetables, stone fruit, tree nuts, bulb vegetables, (ground spray)
1 app at 0.133 lb ai/A

Runoff to dry areas (A/I)*R 0.00266

Runoff to semi

- aquatic areas (A/I)*R*10 0.0266 Spray drift A*D 0.00133 Total for dry areas ((A/I)*R)+(A*D) 0.00399

Total for semi

- aquatic areas ((A/I)*R*10)+(A*D) 0.02793
Citrus (chemigation)
1 app at 0.391 lb ai/A

Runoff to dry areas (A/I)*R 0.00782

Runoff to semi

- aquatic areas (A/I)*R*10 0.0782 Spray drift A*D 0.01955 Total for dry areas ((A/I)*R)+(A*D) 0.02737

Total for semi

- aquatic areas ((A/I)*R*10)+(A*D) 0.09775

### 55 Description Equation EEC (lb ai/A)

Cucurbits, fruiting vegetables, potted ornamentals ( drip chemigation /soil drench )
1 app at 0.130 lb ai/A

Runoff to dry areas (A/I)*R 0.0026

Runoff to semi

- aquatic areas (A/I)*R*10 0.026 Spray drift A*D 0.0013 Total for dry areas ((A/I)*R)+(A*D) 0.0039

Total for semi

- aquatic areas ((A/I)*R*10)+(A*D) 0.0273
Cucurbits, fruiting vegetables, leafy vegetables, ( drip chemigation)
1 app at 0.35 lb ai/A

Runoff to dry areas (A/I)*R 0.007

Runoff to semi

- aquatic areas (A/I)*R*10 0.07 Spray drift A*D 0.0035 Total for dry areas ((A/I)*R)+(A*D) 0.0105

Total for semi

- aquatic areas ((A/I)*R*10)+(A*D) 0.0735

Potato (seed treatment)
1 app at 0.69 lb ai/A

– incorporation 3 inches

Runoff to dry areas (A/I)*R 0.0046

Runoff to semi

- aquatic areas (A/I)*R*10 0.046 Total for dry areas ((A/I)*R)+(A*D) 0.0115

Total for semi

- aquatic areas ((A/I)*R*10)+(A*D) 0.0529

Potato (seed treatment)
1 app at 0.176 lb ai/A

– incorporation 3 inches

Runoff to dry areas (A/I)*R 0.001173333

Runoff to semi

- aquatic areas (A/I)*R*10 0.011733333 Total for dry areas ((A/I)*R)+(A*D) 0.002933333

Total for semi

- aquatic areas ((A/I)*R*10)+(A*D) 0.013493333
Rapeseed including canola varie ties, mustard seed (seed treatment)
1 app at 0.4 lb ai/A

– no incorporation

Runoff to dry areas (A/I)*R 0.008

Runoff to semi

- aquatic areas (A/I)*R*10 0.08 Total for dry areas ((A/I)*R)+(A*D) 0.012

Total for semi

- aquatic areas ((A/I)*R*10)+(A*D) 0.084
Sunflower (seed treatment)
1 app at 0.016 lb ai/A

– 1 inch incorporation

Runoff to dry areas (A/I)*R 0.00032

Runoff to semi

- aquatic areas (A/I)*R*10 0.0032 Total for dry areas ((A/I)*R)+(A*D) 0.00048

Total for semi

- aquatic areas ((A/I)*R*10)+(A*D) 0.00336
Corm and tuberous vegetables (soil)
1 app at 0.25 lb ai/A

Runoff to dry areas (A/I)*R 0.005

Runoff to semi

- aquatic areas (A/I)*R*10 0.05 Spray drift A*D 0.0025

### 56 Description Equation EEC (lb ai/A)

Total for dry areas ((A/I)*R)+(A*D) 0.0075

Total for semi

- aquatic areas ((A/I)*R*10)+(A*D) 0.0525

Flowerbeds and groundcovers (ground spray)
1 app at 0.208 lb ai/A

Runoff to dry areas (A/I)*R 0.00416

Runoff to semi

- aquatic areas (A/I)*R*10 0.0416 Spray drift A*D 0.00208 Total for dry areas ((A/I)*R)+(A*D) 0.00624

Total for semi

- aquatic areas ((A/I)*R*10)+(A*D) 0.04368
Ornamental plants, fruit and nut trees (non

- bearing), and forest seedlings grown in greenhouses, lath and

shade houses , containers, field nurseries, and interiorscapes

, turf, golf courses, residential lawns,
commercial grounds, parks, playgrounds, athletic fields, sod farms, grassy, weedy, mulched, or bare soil
areas in and around greenhouses, nurseries, interior plantscapes, lath and shade house , under trees and
shrubs that are being grown in

- ground (ground spray)
1 app at 0.26 lb ai/A

Runoff to dry areas (A/I)*R 0.0052

Runoff to semi

- aquatic areas (A/I)*R*10 0.052 Spray drift A*D 0.0026 Total for dry areas ((A/I)*R)+(A*D) 0.0078

Total for semi

- aquatic areas ((A/I)*R*10)+(A*D) 0.0546
Ornamental plants (exterior landscapes and interior plantscapes) , trees (including non

- bearing fruit and

nut trees), shrubs, evergreens, bedding plants, flowering plants, flowers, foliage plants, groundcovers,
vines, interior plantscape plants, vegetable transplants (fruiting, leafy corm, tuberous), public health

insect control (ground spray /soil drench )
1 app at 0.42 lb ai/A

Runoff to dry areas (A/I)*R 0.0084

Runoff to semi

- aquatic areas (A/I)*R*10 0.084 Spray drift A*D 0.0042 Total for dry areas ((A/I)*R)+(A*D) 0.0126

Total for semi

- aquatic areas ((A/I)*R*10)+(A*D) 0.0882
Fly control bait (granular)
1 app at 0.087 lb ai/A

Runoff to dry areas (A/I)*R 0.00174

Runoff to semi

- aquatic areas (A/I)*R*10 0.0174 Spray drift A*D 0 Total for dry areas ((A/I)*R)+(A*D) 0.00174

Total for semi

- aquatic areas ((A/I)*R*10)+(A*D) 0.0174

Potted ornamentals (soil drench)
1 app at 0.5 lb ai/A

Runoff to dry areas (A/I)*R 0.01

Runoff to semi

- aquatic areas (A/I)*R*10 0.1 Spray drift A*D 0.005 Total for dry areas ((A/I)*R)+(A*D) 0.015

### 57 Description Equation EEC (lb ai/A)

Total for semi

- aquatic areas ((A/I)*R*10)+(A*D) 0.105

Potted ornamentals (soil drench)
1 app at 0.13 lb ai/A

Runoff to dry areas (A/I)*R 0.0026

Runoff to semi

- aquatic areas (A/I)*R*10 0.026 Spray drift A*D 0.0013 Total for dry areas ((A/I)*R)+(A*D) 0.0039

Total for semi

- aquatic areas ((A/I)*R*10)+(A*D) 0.0273
A = application rate I = incorporation

R = runoff fraction

D = drift fraction



### C. Ecological Effects Characterization

Based on the available data, cyantraniliprole is classified as slightly to moderately toxic to freshwater fish; slightly toxic to estuarine/marine fish; slightly to very highly toxic to freshwater invertebrates; moderately to highly toxic to estuarine/mari ne invertebrates, highly toxic to benthic invertebrates; highly to very highly toxic to terrestrial insects; and practically non

- toxic to mammals and birds on an acute exposure basis. Chronic exposure resulted in effects on growth in freshwater invertebra tes and estuarine/marine fish. Chronic exposure in mammals resulted in effects on thyroid weight and on growth of rat offspring; however, no effects were detected in birds at the dietary levels tested. For terrestrial plants, the EC 25 

### value s were greater than 0.134 lb ai/A for both seedling emergence and vegetative vigor tests. Both vascular and non

- vascular aquatic plants

exhibited non

- definitive EC 50 

### >1 0 mg ai/L

.

1. Aquatic Effects Characterization

a. Aquatic Animals

Three acute t oxicity st udies were submitted for freshwater fish

. The LC 50 

### value s were all

non

- definitive >10 mg total ai/L ( Table 2 1 ) and cyantraniliprole’s toxicity may be limited by its solubility . All of the studies were classified as “supplemental” because undissolved test material was observed in several of the higher concentration levels. Samples from each treatment were measured; however, the samples were not centrifuged or filtered prior to analysis. Therefore, the amount of cyantraniliprole dissolved in the

test solution is unknown. The data are still considered useable because the toxicity endpoint was assumed to be at or higher than the solubility of the test material . The product chem istry data identified a solubility limit of 14.2 mg ai/L at 20oC

, but the conditions under which it was performed ( e.g ., temperature) were probably different than the toxicity studies , thus explaining the precipitate at the lower concentrations in the

stud ies . No mortalities were reported

. Sub

- lethal effects for the technical grade active

### 58 ingredient included : lethargy

, surfacing for long periods of time, and lying on the bottom

of the test chamber.

The four a cute toxicity studies with the formulations w ere more varied than technical

grade cyantraniliprole ( Table 2 2 ) ; this could be the result of emulsifiers or other inert ingredients in the formulations. Bluegill sunfish ( Lepomis macrochirus ; MRID

48120220 ) yielded the most sensitive toxicity value of al l the acute freshwater fish toxicity tests with an LC 50 

### of 2.4 mg ai/L . E ndpoints from studies with t ypical end

- use product ( TEP ) are not used to calculate risk quotients for aquatic species because

formulation constituent s are expected to move differentially through the environment and are not expected to exist in the same ratio as the original formulation upon being dissolved in water. Thus, at a screening level, it is assumed that fish would be exposed to cyantraniliprole by itself, and not i n conjunction with the other ingredients in the

formulation

. However, as this is the most sensitive endpoint for freshwater fish, it wi ll be discussed further in the Risk Description section of the document and will be considered in the spray drift analys is , if appropriate

. The other TEP tests yielded LC 50 

### value s from >7.9 to >40.7 mg ai/L. Three of the studies were classified as “acceptable;” the endpoints in the one “supplemental” study were based on nominal concentrations although the measured concent rations were below 80% at the test’s end. Sub

- lethal

effects from the studies using TEP included: surfacing for long periods of time, lethargy, lying on the bottom of the test chamber, rapid opercular movement ( breathing ) , tumbling while swimming, and da rk coloration. Overall

, and based on the measured LC 50 

### values

, cyantraniliprole is slightly to moderately toxic t o freshwater fish on an acute exposure
basis

.

A chronic early life

- stage study was available for rainbow trout ( Oncorhynchus mykiss ; Table 2 1 ) . The study yielded a NOAEC of 10.7 mg ai/L and no mortality or sub

- lethal

effects were observed.

Table 2 1

. Summary of Acute and Chronic Toxicity to Freshwater F ish

Study Test Material Species Toxicity Endpoint (mg ai/L) Classification and

MRID

Acute toxicity to

freshwater fish TGAI (93.4%) Rainbow trout

( Oncorhynchus mykiss ) 96

- hr LC 50 >12.6 mg total ai/L

NOAEC = 6.87

mg total ai/L Supplemental

48120108

Acute toxicity to

freshwater fish TGAI (93.4%) Bluegill sunfish

( Lepomis

macrochirus ) 96

- hr LC 50 >13 mg total ai/L

NOAEC = 6.97

m g total ai/L Supplemental

48120104

Acute toxicity to

freshwater fish TGAI (94.5%) Channel catfish

( Ictalurus

punctatus ) 96

- hr LC 50 >10 mg total ai/L

NOAEC = 10 m g total ai/L Supplemental

48120106

### 59 Study Test Material Species Toxicity Endpoint (mg ai/L) Classification and

MRID

Acute toxicity to
freshwater fish TEP (18.66%) Bluegill sunfish

( Lepomis

macrochirus ) 96

- hr LC 50 >7.9

NOAEC =1.1 Acceptable

48120321

Acute toxicity to

freshwater fish TEP (10.26%) Bluegill sunfish

( Lepomis

macrochirus ) 96

- hr LC 50 =2.4 * *

NOAEC = 0.76 Acceptable

48120220

Acute toxicity to

freshwater fish TEP (20.6%)

Other ai

– thiamethoxam (20.6%) Rainbow trout

( Oncorhynchus mykiss ) 96

- hr LC 50 >11.12

NOAEC =11.12 Supplemental

48432527

Acute toxicity to

freshwater fish TEP (40.7%) Rainbow trout

( Oncorhynchus mykiss ) 96

- hr LC 50 >40.7

NOAEC =3.83 Acceptable

48432413

Freshwater fish early life

- stage TGAI (94.5%) Rainbow trout

( Oncorhynchus mykiss ) NOAEC =10.7 *

LOAEC >10.7

No effects Acceptable

48120109

TGAI = technical grade active ingredient TEP = typical end

- use product *denotes endpoint used in risk quotient calculations **may be considered in spray drift analysis



### One acute toxicity test for estuarine/marine sheepshead minnow ( Cyprinodon variegatus )

was submitted ( Table 22 )

. Similar to studies with freshwater fish, t he test was classified as “supplemental” because undissolved test material was present in some of the test

chambers. Measured samples were taken, but they were not centrifuged or filtered; thus

, the actual amount of cyantraniliprole dissolved in solution is unknown. The toxicity endpoint i s still considered useable because it i s at the apparent solubility limit of the test

chemical (see freshwater fish discussion above for more detail)

. No mort alities or sub

lethal effects were reported. The results of this test indicate that cyantraniliprole is slightly toxic to estuarine/marine fish on an acute exposure basis.

One chronic study was available for estuarine/marine fish using sheepshead minnow ( Table 22 ) . The study was classified as “supplemental” because there was undissolved

test material in the three highest test concentrations. This is not anticipated to affect the interpretation of this study’s toxicological endpoints because the NOAEC an d LOAEC were both at or below the lowest concentration tested; no undissolved test material was

observed at this concentration or the concentration above it . There were no effects on survival or hatching rates. Growth parameters (length and weight) were affected with the most sensitive being fish length. Given that the NOAEC ( NOAEC <0.75 mg ai /L ) 

### in this study is a “less than” value, the lower bounds of cyantraniliprole’s toxicity are

unknown in estuarine/marine fish.

### 60 Table 2 2

. Summary of Acute and Ch ronic Toxicity to Estuarine/Marine F ish

Study Test Material Species Toxicity Endpoint (mg ai/L) Classification and

MRID

Acute toxicity to

estuarine/marine

fish TGAI (94.5%) Sheepshead

minnow

( Cyprinodon variegatus ) 96

- hr LC 50 > 12 mg total ai/L

NOAEC = 12 m g total ai/L Supplemental

48120105

Estuarine/marine fish early life

- stage TGAI (94.5%) Sheepshead

minnow

( Cyprinodon variegatus ) NOAEC <0.75

LOAEC =0.75

Based on mean measured length Supplemental

48120110

TGAI

– technical grade active ingredient



### Acute toxicit y studies were submitted for seven species of freshwater invertebrates ( Table 23 ) . For the seven studies conducted with the technical material, 48

- hr EC 50 

### value s ranged from 20.4 to >14000 μg ai/L. The most sensitive species was the water
flea ( Daphnia magna ) with an EC 50 

### of 20.4 μg ai/L

. For all species, l ethargy and floating

at the surface were the only sub

- lethal effects reported. The amphipod study with Hyalella azteca was classif ie d as “supplemental” because of a potential methodological problem at one treatment level

– a number of behavioral effects were seen at the lowest concentration tested, but these did not carry through to higher concentra tions. It is uncertain if these were real effects or an artifact of the experiment. The NOAEC was conservatively assigned to be lower than this value (< 76.4 μg ai/L).

Six studies were performed with various TEPs ( Table 23 )

. The 48

- hr EC 50 

### value s ranged

from 5 .6 (thiamethoxam

- containing product) to 18.5 μg ai/L and were all more sensitive than their TGAI counterpart conducted with D. magna . Two of the studies with D.

magna (MRIDs 48432528 and 48432414) were classified as “supplemental” because the toxicity end points were based on nominal concentrations ; whereas

, measured concentrations indicated a decrease of more than 20% of the test material throughout the study. Sub

- lethal effects included lethargy and floating at the surface. Overall, the TEP

and TGAI tes ts indicate that cyantraniliprole is slightly toxic to very highly toxic to
freshwater invertebrates on an acute exposure basis.

One freshwater invertebrate chronic study was available with D. magna ( Table 23 ) . The most sensitive endpoint was adult bo dy length (NOAEC = 6.56 μg ai/L) , but adult

survival and total number of immobilized live young (NOAEC = 9.69 μg ai/L) ; and total number of live young and dry weight were also affected (NOAEC = 14.7 μg ai/L)

.

Table 2 3

. Summary of Acute and Chronic Toxi city to Freshwater I nvertebrates

Study Test Material Species Toxicity Endpoint (μg ai/L) Classification and

MRID
Acute toxicity to

freshwater

invertebrates TGAI (93.3%) Water flea

( Daphnia magna ) 48

- hr EC 50 = 20.4 *

NOAEC = 1.70 Acceptable

48120114

### 61 Study Test Material Species Toxicity Endpoint (μg ai/L) Classification and

MRID

Acute toxicity to

freshwater

invertebrates TGAI (93.3%) Mayfly

( Centroptilum triangulifer ) 48

- hr LC 50 =71.5

NOAEC =11.1 Acceptable

48120099

Acute toxicity to

freshwater

invertebrates TGAI (93.3%) Caddisfly

( Lepidostoma

ontario ) 48

- hr LC 50 =74.8

NOAEC =11.5 Acceptable

48120117

Acute toxicity to

freshwater

invertebrates TGAI (93.4%) Stonefly

( Soyedina

carolinensis ) 48

- hr LC 50 = 14000

NOAEC <1050 Acceptable

48120103

Acute toxicity to

freshwater

invertebrates TGAI (93.4%) Amphipod

( Gammarus pseudolimnaeus ) 48

- hr LC 50 =172

NOAEC =73.3 Acceptable

48120098

Acute toxicity to

freshwater

invertebrates TGAI (93.4%) Amphipod

( Hyalella azteca ) 48

- hr LC 50 >1370

NOAEC = <76.4 Supplemental

48120102

Acute toxicity to

freshwater

invertebrates TGAI (93.4%) Oligochaete

( Lumbriculus variegatus ) 48

- hr LC 50 >13700

NOAEC <860 Acceptable

48120101

Acute toxicity to

freshwater

invertebrates TEP (10.26%) Water flea

( Daphnia magna ) 48

- hr EC 50 = 9.47

NOAEC = <3.28 Acceptable

48120217 Acute toxicity to

freshwater

invertebrates TEP (10.26%) Water flea

( Daphnia magna ) 48

- hr EC 50 =18

NOAEC =8.13 Acceptable

48120242 Acute toxicity to

freshwater

invertebrates TEP (10.26%) Water flea

( Daphnia magna ) 48

- hr EC 50 =18.5

NOAEC =3.54 Acceptable

48120415 Acute toxicity to

freshwater

invertebrates TEP (18.66%) Water flea

( Daphnia magna ) 48

- hr EC 50 = 14 .5

NOAEC = 9 .13 Acceptable

48120319

Acute toxicity to

freshwater

invertebrates TEP (20.6%)

Other ai

– thiamethoxam (20.6%) Water flea

( Daphnia magna ) 48

- hr EC 50 =5.6 **

NOAEC <0.21 Supplemental

48432528

Acute toxicity to

freshwater

invertebrates TEP (40.7%) Water flea

( Daphnia magna ) 48

- hr EC 50 = 11

NOAEC <1.2 Supplemental

48432414

Chronic test to

freshwater

invertebrates TGAI (93.3%) Water flea

( Daphnia magna ) NOAEC = 6.56*

LOAEC = 96.9

Based on adult

body length Acceptable

48120091

TGAI

– technical grade active ingredient

TEP

– typical end

- use product *denotes endpoint used in risk quotient calculations **considered in spray drift analysis

### 62 Two acute toxicity studies were available for estuarine/marine invertebrates ( Table 24 )

. The shell deposition study with the Eastern oyster yielded the most sensitive endpoints ( 96

- hr EC 50 

### = 520 μg ai/L)

. Oyster shell growth was the only parameter that was affected; no other sub

- lethal effects or mortality were reported. In the acute toxicity test

with mysid shrimp , shrimp exhibited erratic swimming and lethargy as sub

- lethal effects. These results classify cyantraniliprole as moderately toxic to highl y toxic to
estuarine/marine invertebrates on an acute exposure basis.

Data were not available for the chronic effects of cyantraniliprole to estuarine/marine invertebrates. In lieu of actual data, the acute

- to

- chronic ratio was used to derive an

estimate of a chronic toxicity value for estuarine/marine invertebrates using the acute

chronic relationship for the most sensitive species of freshwater invertebrates. The following equation was used:

E C 50( oyster ) 

### = EC 50 ( water flea ) 

### = 520 = 20.4 = 167 = NOAEC (oyster ) 

### NOAEC (oyster ) 

### NOAEC ( water flea ) 

### X 6.56

Normally an ACR is calculated with the most sensitive mortality endpoint. For the cyantraniliprole dataset, the E astern oyster yielded the most sensitive endpoint, but it was

base d on growth rather than mortality. Consequently, an ACR based on the acute mysid shrimp endpoint (mortality) was also considered.

E C 50( shrimp ) 

### = EC 50 ( water flea ) 

### = 1200 = 20.4 = 386 = NOAEC (shrimp ) 

### NOAEC (shrimp ) 

### NOAEC ( water flea ) 

### X 6.56

Table 2 4

. Summary of Acute and Chronic Toxicity to E stuarin e/Marine

I nvertebrates

Study Test Material Species Toxicity Endpoints (μg ai/L) Classification and

MRID

Acute toxicity to

estuarine/marine

invertebrate TGAI (93.4%) Mysid shrimp

( Americamysis

bahia ) 96

- hr LC 50 = 1200

NOAEC = 370 Acceptable

48120096

Oyster shell deposition toxicity

test TGAI (93.4%) Eastern oyster

( Crassostrea

virginica ) 96

- hr EC 50 = 520*

NOAEC = 110 Acceptable

48120095

Chronic toxicity to

estuarine/marine

invertebrates ACR Eastern oyster

( Crassostrea

virginica ) NOAEC = 167* ACR

Chronic toxicity to

estuarine/marine

invertebrates ACR Mysid shrimp

( Americamysis

bahia ) NOAEC = 386* ACR

TGAI

– technical grade active ingredient

### 63 Study Test Material Species Toxicity Endpoints (μg ai/L) Classification and

MRID

ACR

– acute

- to

- chronic ratio

– see text above table for a description of the calculation *denotes endpoint used in risk quotient calculations



### One water column study was available for the acute toxicity effects to sediment

- dwelling midge ( Chironomous riparius ) ( Table 2 5 ) . The study reported lethargy as the only sub

lethal effect. The data indicate that cyantraniliprole is highly toxic ( 48

- hr LC 50 

### = 719 μg

ai/L ) to sediment

- dwelling organisms , on an acute exposure basis

.

Two chronic toxicity test s were available for the midge ( Table 2 5 )

. MRID 48120092 used spiked sediment while MRID 48120093 used spiked water. The spiked water study

was the most sensitive , but was classified as “supplemental” because of its methodology (Agency guidelines require spike d sediment, not spiked water). In addition, there was a solvent effect in the emergence endpoint. Other endpoints (development rate and time)

were not affected by the solvent , and were compared directly to the negative control as stipulated by Agency gui delines. T herefore, these endpoints are considered scientifically

sound and were chosen for use in the risk assessment because they are more sensitive than those presented in the “acceptable” study . No s ub

- lethal effects were observed in either spiked wa ter or sediment studies

.

Table 25

. Summary of Acute and C h ronic Toxicity to Sediment

- Dwelling

O rganisms

Study Test Material Species Toxicity Endpoint (μg ai/L) Classification and

MRID

Acute toxicity to

sediment

- dwelling organisms TGAI (93.4%) Midge

( Chironomus

riparius ) 48

- hr LC 50 = 719 *

NOAEC <395 Acceptable

48120094

Chronic toxicity to

sediment

- dwelling organisms TGAI (93.4%) Midge

( Chironomus

riparius ) NOAEC =10 *

LOAEC >10

Based on development rate

and time Supplemental

48120093

Chronic toxicity to

sediment

- dwelling organisms TGAI (93.4%) Midge

( Chironomus

riparius ) NOAEC =19

LOAEC >19

Based on adult

emergence Acceptable

48120092

TGAI

– technical grade active ingredient *denotes endpoint used in risk quotient calculations



### c. Aquatic Plants

One vascular aquatic plant study with duckweed ( Lemna gibba ) was submitted ( Table

26 ) . The 7

- day EC 50 

### was non

- definitive ( >12100 μg ai/L) and was based on inhibition of

### 64 frond count, biomass, and growth rate. The most sensitive NOAEC (1000 μg ai/L) was associated with frond count and its corresponding growth rate.

Four s tudies were submitted for toxicological effects to non

- vascular aquatic plants with

tech nical

- grade cyantraniliprole ( Table 2 6 ) . These studies included a cyanobact eria (blue

- green algae; Anabaena flos

- aquae) , a freshwater diatom ( Navicula pelliculosa ), a green algae ( Pseudokirchneriella subcapitata ), and a marine diatom ( Skeletonema

costatum )

. All of the EC 50 

### values were non

- definitive (ranging from >10000 to >15 00 0 μg ai/L) and were based on inhibition of cell count and biomass

. Three of the studies

with were classified as “supplemental” because either the test duration was 72 hours versus 96 (MRID 48120107) (green algae) , or precipitate was noted in the highest

c oncentration of test solution (MRIDs 48122541, 48122542) (cyanobacteria and estuarine/marine diatoms)

. Measured samples from the studies containing precipitate were not centrifuged or filtered prior to analysis; thus there is uncertainty as to the

amount of cyantraniliprole that was biologically available (dissolved) in the solution. Cell density was the most sensitive endpoint for the marine diatom and cyan o bacteria

with an EC 50 

### >10000 and >15000 μg total ai/L , respectively, where inhibition ranged from 30 to 39 % in the highest concentration tested. Precipitate was not observed in the green algae and freshwater diatom studies with an EC 50 

### > 13000 and >14000 μg ai/L

, respectively . These endpoints are similar to the studies contain ing precipitate and support the claim that the EC 50 

### i s greater than the solubility limit of the test material ( i.e

., 14200 μg ai/L)

.

Five green algae studies were available for cyantraniliprole typical end

- use products ( Table 2 6 ) . These yielded EC 50 

### valu e s that ranged from 825 to 9900 μg ai/L . The most sensitive endpoint (EC 50 

### = 825 μg ai/L) was based on inhibition of cell count

. Although this endpoint is more sensitive than the TGAI endpoint, it is generally not used to derive risk quotients. It may b e considered in the spray drift analysis, if appropriate. Four of the studies (MRIDs 48120221, 48120416, 48120323 , 48432415 ) were classified as “supplemental” because the test duration was 72 hours instead of 96 . This may have resulted in slightly higher endpoints than if the study had been allowed to continue for another 24 hours; however, the endpoints are not expected to be appreciably different and are considered scientifically sound. The other two studies (MRIDs 48432529, 48432415)

were classified a s “supplemental” because the endpoints were calculated from nominal values, but measurements indic ated the test concentrations deviate d more than 20% from

the nominal concentrations. This may have under

- estimated the toxicity endpoints.

Table 2 6

. Summary of Toxicity Data for Vascular and Non

- Vascular P lants

Study Test Material Species Toxicity Endpoint (μg ai/L) Classification and

MRID

Toxicity to vascular aquatic plants TGAI (94.5%) Duckweed

( Lemna gibba ) 7

- day EC 50 > 12100

NOAEC = 1000 Acceptable

48122543

Toxicity to non

vascular plants TGAI (94.5%) Green algae

( Pseudokirchneriella 72

- hr EC 50 >
13000 Supplemental

48120107

### 65 Study Test Material Species Toxicity Endpoint (μg ai/L) Classification and

MRID

subcapitata ) NOAEC = 3200

Toxicity to non

vascular plants TGAI (94.5%) Blue

- green algae (cyanobacteria)

( Anabaena flos

aquae ) 96

- hr EC 50 >
15000 μg total

ai/L

NOAEC = 15000 μg total ai/L Supplemental

48122541

Toxicity to non

vascular plants TGAI (94.5%) Freshwater diatom

( Navicula pelliculosa ) 96

- hr EC 50 >
14000

NOAEC = 14000 Acceptable

48120157

Toxicity to non

vascular plants TGAI (94.5%) Estuarine/marine

diatom

( Skeletonema

costatum ) 96

- hr EC 50 > 10000 μg total

ai/L

NOAEC = 1000

μg total ai/L Supplemental

48122542

Toxicity to non

vascular plants TEP (10.26%) Green algae

( Pseudokirchneriella subcapitata ) 72

- hr EC 50 = 1180

NOAEC = 295 Supplemental

48120221

Toxicity to non

vascular plants TEP (10.26%) Green algae

( Pseudokirchneriella subcapitata ) 72

- hr EC 50 = 825 * *

NOAEC = 217 Supplemental

48120416

Toxicity to non

vascular plants TEP (18.66%) Green algae

( Pseudokirchneriella subcapitata ) 72

- hr EC 50 = 7370

NOAEC = 4040 Supplemental

48120323

Toxicity to non

vascular plants TEP (20.6%)

Other ai

– thiamethoxam (20.6%) Green algae

( Pseudokirchneriella subcapitata ) 96

- hr EC 50 = 9900

NOAEC = 660 Supplemental

48432529

Toxicity to non

vascular plants TEP (40.7%) Green algae

( Pseudokirchneriella subcapitata ) 72

- hr EC 50 = 6500

NOAEC < 407 Supplemental

48432415

TGAI

– technical grade active ingredient

TEP

– typical end

- use product **may be considered in spray drift analysis



### 2. Terrestrial Effects Characterization

a. Terrestrial Animals

Birds

Four acute oral toxicity studies of birds were submitted for cyantraniliprole ; one bobwhite quail ( Colinus virginianus ) and one zebra finch ( Poephila guttata ) study were

### 66 conducted with technical grade cyantraniliprole ; two quail studies were conducted with typical end

- use products ( Table 27 ) . All LD 50 

### value s were non

- definitive; no sub

- lethal

effects w ere observed. Based on the acute oral toxicity studies, cyantraniliprole is

cl assified as practically non

- toxic to moderately toxic to avian species on an acute oral exposure basis

. Similarly, two sub

- acute dietary studies were submitted with northern

bo bwhite quail and mallard duck s ( Anas platyrhynchos ) . These studies resulted in non

definitive values and did not exhibit any sub

- lethal effects. Based on the LC 50 

### value s
, cyantraniliprole is practically non

- toxic to birds on a sub

- acute dietary exposure basis

.

Two avian reproduction studies were submitted to determine the effects of cyantraniliprole on a chronic basis ( Table 27 ) . Mallard duck and northern bobwhite quail

were tes t ed; no effects were observed in either study up to the highest dietary level tested,

i.e ., 1000 mg ai /kg diet . The NOAEC was set at the highest test concentration tested and

the LOAEC was determined to be above this concentration.

Table 27

. Summary of Acute and Chronic Toxicity to B irds

Study Tes t Material Species Toxicity Endpoint Classification and

MRID

Acute avian oral toxicity TGAI ( 93.3%) Northern bobwhite quail

( Colinus virginianus ) LD 50 >2250 mg ai/kg

- bw

NOAEC = 2250

mg ai/kg

- bw Acceptable

48120153

Acute avian oral toxicity TGAI (94.5%) Zebra finch

( Poephila guttata ) LD 50 >2250 mg ai/kg

- bw

NOAEC = 2250

mg ai/kg

- bw Acceptable

48120171

Acute avian oral toxicity TEP (10.26%) Northern bobwhite quail

( Colinus virginianus ) LD 50 >230.85 mg ai/kg

- bw

NOAEC = 230 mg ai/kg

- bw Acceptable

48120218

Acute avian oral toxicity TEP (18.66%) Northern bobwhite quail

( Colinus virginianus ) LD 50 >376.9 mg ai/kg

- bw

NOAEC = 376.9

mg ai/kg

- bw Acceptable

48120305

Acute avian dietary toxicity TGAI (93.3%) Northern bobwhite quail

( Colinus virginianus ) LC 50 >5620 mg ai/kg

- diet

NOAEC = 5620

mg ai/kg

- diet Acceptable

48120128

Acute avian dietary toxicity TGAI (93.3%) Mallard duck

( Anas platyrhynchos ) LC 50 > 5620 mg ai/kg

- diet

NOAEC = 5620

mg ai/kg

- diet Acceptable

48120127

Chronic avian toxicity TGAI (93.3%) Mallard duck

( Anas platyrhynchos ) NOAEC = 1000* mg ai/kg

- diet

LOAEC > 1000

mg ai/kg

- diet Acceptable

48120115

### 67 Study Tes t Material Species Toxicity Endpoint Classification and

MRID

Chronic avian toxicity TGAI (93.3%) Northern bobwhite quail

( Colinus virginianus ) NOAEC = 1000* mg ai/kg

- diet

LOAEC > 1000 mg ai/kg

- diet Acceptable

48120116

TGAI

– technical grade active ingredient

TEP

– typical end

- use product *denotes endpoint used in risk quotient calculations



### Mammals

The acute oral toxicity study for rats ( Rattus norvegicus ) indicated a non

- definitive LD 50 

### of > 5000 mg ai/kg

- bw ( Table 28 ) . No sub

- lethal effects were observed and no mortalities occurred during the test. Based on these results, cyantraniliprole is classified as practically non

- toxic to mammals on an acute oral exposure basis.

The two

- generation reproduction study in rats was used to quantify the chronic effects of exposure to cyantraniliprole ( Table 2 8 ) . The parent NOAEL (20 mg ai/kg diet; 1.4 mg ai/kg/day ) was based on thyroid weight increase and correspondi ng dose

- related increase in the incidence of thyroid follicular epithelial cell hypertrophy/hyperplasia. The offspring NOAEL (200 mg ai/kg diet; 14 mg ai/kg/day ) 

### was based on dose

- related decreases in organ weights (thymus and spleen) and pup body weight decrease in the F 2 

### generation. Other effects in offspring included: dehydration, decreased body weight in

the F 1 

### generation at highest dose, decreases in brain weight, and decrease in the F 2 

### adrenal gland weight. N o effects were observed for reproductio n and fertility endpoint s ; thus, the NOAEL was set at the highest concentration tested (20000 mg ai/kg

- diet ; 1344 mg ai/kg/day ).

### 68 Table 2 8

. Summary of Acute and Chronic Toxicity for M ammals

Study Test Material Species Toxicity Endpoints MRID

Acute oral toxicity TGAI (94.5%) Rat

( Rattus norvegicus ) LD 50 >5000 mg ai/kg

- bw 48208417

Two

- generation reproduction study TGAI (94.5) Rat

( Rattus norvegicus ) Parent NOAEL =20 ppm (1.4 mg ai/kg/day)*

LOAEL =200 ppm (14 mg ai/kg/day)

Reproductive and Fertility NOAEL =20000 ppm (1344 mg ai/kg/day)

LOAEL >20000 ppm (1344 mg ai/kg/day)

Offspring NOAEL = 200 ppm (14 mg ai/kg/day)

LOAEL = 2000 ppm (136 mg ai/kg/day) 48119967

TGAI

– technical grade active ingredient *denotes value used in risk quotient calculations



### Terrestrial Invertebrates

Given that cyantraniliprole is an insecticide, a disproportionately large number of studies were submitted for terrestrial invertebrates, in comparison with other taxa considered in ecological risk assessments. As a systemic, cross

- spectrum chemical, these studies are meant to demonstrate the effects that cyantraniliprole could have on non

- target and beneficial insects; studies consider different exposure levels, the nature of the effects, and their persistence. I n particular, the honeybee data are tiered and offer information about potential effects to indiv iduals and whole colony effects. As studies become more complex (semi

- field and field studies), conclusions are generally qualitative as the

num er ous variable s and lack of replicates do not allow for statistical analysis. The studies are segregated into three sections: honeybees, earthworms, and other terrestrial

invertebrates.

Honeybees

One guideline honeybee (acute contact toxicity ) and one non

- guideline honeybee (oral toxicity ) test were submitted for technical

- grade cyantraniliprole ( Table 29 ) . The LD 50 

### values were both non

- definitive (contact LD 50 

### >0.0934 and oral LD 50 

### >0.1055 μg ai/bee); a NOAEC of 0.0234 μg ai/bee was establis hed for the contact test. Lethargy was the only reported sub

- lethal effect and mortality was 2% (oral) and 34% (contact) at the highest treatment level

. Although both studies resulted in non

- definitive endpoints, since the studies did not test higher con centrations of cyantraniliprole, the chemical is

classif ied as highly toxic to terrestrial in vertebrates on both an acute oral and acute contact exposure basis

.

### 69 In addition, acute oral (5 studies) and contact tests (4 studies) were submitted using typical end

- use products ( Table 29 ) . Contact LD 50 

### value s ranged from 0.55 to 3.03 μg

ai/bee and oral LD 50 

### value s ranged from 0.116 to 0.92 μg ai/bee for studies with cyantraniliprole as the sole active ingredient . S ub

- lethal effects included letharg y and

abnormal behavior. The relative toxicity of the technical grade active ingredient to the formulated products is an uncertainty since exposure to the TGAI resulted in non

definitive values. The cyantraniliprole

- thiamethoxam formulation study yielded an ac ute

contact LD 50 

### of 0.058 μg ai/bee and an acute oral LD 50 

### of 0.0062 μg ai/bee indicating

that this formulation is more toxic to honeybees than technical cyantraniliprole. Given

that thiame thoxam is highly toxic to bees (contact LD 50 

### = 0.024 μg ai/bee; or al LD 50 

### = 0.005 μg ai/bee) , it is likely that the presence of this insecticide is contributing to the overall toxicity of the cyantraniliprole

- thiamethoxam formulation (USEPA 2011c, DP391191)

.

A foliage residues toxicity test (MRID 48120132 ) was perform ed to determine a residual contact toxicity duration for treated foliage. Alfalfa foliage was sprayed at a concentration of 0.12 lb ai/A and allowed to age for 3 to 72 hours. The dry foliage was then harvested and placed in test chambers with bees. The RT 25 

### was less than 3 hours, indicating that at three hours after application, there was less than 25% mortality in bees coming into contact with treated foliage (actual mortality was ≤13%). Some sub

- lethal effects were observed (loss of equilibrium, immob ility, lethargy), but these represented less than 2% of the bees in the treatment groups. The results of this test are only applicable to contact toxicity.

Multiple semi

- field and field studies were performed with the honeybee. All of the

studies were classified as “supplemental” because they contained methodological

inconsistencies ; however, it was felt that some useful information could be gleaned from

the studies . The most serious methodological problems with the studies are that 1) the y did not inc lude replication such that potential treatment effects could be statistical ly

tested

, and 2) that study colonies were apparently monitored in areas (following treatment) that did not appear to provide adequate forage and as a result, the colonies

started t o falter. Although the decline in colony strength was attributed by the study authors to colony overwintering, the declines were apparently in advance of when colonies would typically be adapting for winter. While it is likely that colonies will lose

som e bees (primarily drones) and that brood production will drop substantially as colonies prepare for overwintering, the basic number of workers should not decline

. Colonies will lose workers during the overwintering process depending on weather ; however, i n some of the submitted field studies the colonies were showing declines by August

, well before the colonies should have been preparing to overwinter. This makes it difficult to discern even qualitative differences between the treatment groups and control s in the submitted studies

.

In many studies, the design placed six honeybee colonies per acre , which may be high, depending on floral resources . A cross studies , the extent to which the study fields were

in bloom was usually not clear . Also, given the early spring time frame in which some of

### 70 the studies were conducted

, agricultural crops may not have been flowering but there may

have been flowering trees that could have served as alternative forage for the study bees

. Weather was also a factor that influenc ed the extent to which bees were foraging in the study; i n at least one study, bees were not foraging at all after treatments presumably

because of weather conditions. If this is the case, then it is unclear whether these weather events may have a lso reduced the residu e levels on the treated crops ( e.g., rain showers)

.

Applications of 0.0089 or 0.089 lb ai/A to wheat treated with artificial honeydew (as an attractant) under semi

- field conditions (tunnel study) resulted in short

- term increases in

bee mortality (2 days) and reductions in worker bee foraging activities (MRID 48120135). Reductions in foraging activities persisted through the end of the experiment

at 6 days after the application of cyantraniliprole. A second semi

- field (tunnel) stud y (MRID 48120136) applied cyantraniliprole to phacelia ( Phacelia tanacetifolia ) at a rate
of 0.089 lb ai/A during ( ≥ 5 bees/m 2 

### ) and after bee flight (night) . The study indicated that applications made while bees were foraging resulted in short

- term [acute] mortality up to one day after the application; there were also changes to behavior and foraging activity . For applications at night, the only observed effect was a reduction in foraging activity when bees became active again . Reductions in foragi ng activity lasted two days after the application ; the study was terminated after the full third day after application

. A

semi

- field (tunnel) study on phacelia ( MRID 48120138 ) examined the effects of two applications of cyantraniliprole at 0.0089 or 0.089 lb ai/A. Bee flight was reduced and mortality increased for both treatment groups when applications were made during bloom and active bee foraging. Effects lasted one (0.0089 lb ai/A) to two days (0.089 lb ai/A) after application. Sub

- lethal effects , i ncluding t ransient signs of intoxication, repellenc y and decreased foraging

, were observed in both treatment groups. The treatments did not appear to affect brood development.

A study of cyantraniliprole co

- formulated with codacide oil applied to phac e lia under

semi

- field (tunnel) conditions ( MRID 48122539 ) tes ted cyantraniliprole at an application

rate of 0.134 lb ai/A. The first application was made prior to hives being placed in the tunnels and the second application (15 days later) was made in the evening when bees were not foraging; hives were covered in foil to prevent contamination. The study

showed that th is application rate increased mortality for two days after treatment and

reduced foraging activity for one day after the application . Some s ymptoms of increased grooming activity and intoxi cation were also observed on the day after treatment . There were no effects to brood development or colony strength , including brood termination rate (percent of brood that die); however brood development w as only measured for 27 days after cyantraniliprole application

.

The 0.134 lb ai/A application rate was tested in another study on oilseed rape ( Brassica

napus ) under semi

- field (tunnel) where the cyantr a nilipro l e was once again co

- formulated

with codac ide oil . Two applications of 0.134 lb ai/A were made prior to crop flowering and hive presence. N o treatment

- related effects on mortality or foraging activity were observed, although some abnormal behaviors (bees flying at hive entrance and cleaning

beha vior) were documented ( MRID 48122546). E ffects on brood development or colony strength were monitored for 28 days after treatment

. No differences between the

### 71 treatments and controls were noted, although the queen was replaced in one of the

treatment grou ps , but it was not considered treatment

- related

.

A nother study where cyantraniliprole was co

- formulated with codacide oil and applied to oilseed rape under semi

- field (tunnel) conditions ( MRID 48122547 ) reported similar

results for mortality and foraging activity as the study discussed in the preceding paragraph. Rates were the same and applications occurred before crop flowering and the introduction of bees into the tunnels. Normal bee behavior was recorded throughout the experiment

. For brood and colony strength, observations were made for 27 days; one dead queen was noted in a treatment group , but was not considered treatment

- related

. Pollen and nectar stores decreased over this time at comparable rates between the

treatments and controls , b ut enough resources remained to support the hive. Colonies treated with the reference item were completely deplete d of pollen and nectar.

In a full field study with oilseed rape, cyantraniliprole

, co

- formulated with codacide oil ( MRID 48122551 ) was teste d at application rates of 0.134 lb ai/A (Treatment 1) and

0.011 lb ai/A (Treatment 2) . The study note d a n increase in mortality (32 dead bees/day in Treatment 1, 17 dead bees/day in Treatment 2, and 7

- 8 dead bees/day in the control) after the second appli cation of each rate ; however, no statistics were employed

. Effects lasted one day after application in Treatment 1 and six days after application in Treatment

2. No effects on flight activity were identified ; however, low flight activity in the

control

, possibly induced by cold weather, may have masked an effect in treated colonies

. Cramping bees and aggressive behavior towards the observer were noted on the day of the treatment; normal behavior was observed beginning one day after application. The

stud y followed brood development and colony strength for 346 days after treatment. The number of brood cells drastically decreased in all hives between the 27 th 

### and 41 st 

### day after cyantraniliprole applicati on (percent decrease: controls 19%; Treatment 1 39%;

Treatment 2 32% ); similarly, total numbers of adult bees decreased from day 54 (June) to day 145 (percent decrease: controls 66 %; Treatment 1 58%; and Treatment 2 71 %)

. Decreases began early in the season and likely signifie d poor foraging conditions for all

of the colonies. A t the end of overwintering, colony sizes had decreased by a factor of 3.7x (Treatment 1) and a factor of roughly 6x (Treatment 2 and control) compared with

hive size at the mid

- June measurement the prece ding summer . Despite these large

decreases in colony strength , the hives survived the winter . All brood and developmental stages were present except in one control hive and one treatment hive (18 hives total in the study).

In another full

- field study ( MRID 48122553 ) in oilseed rape, resear c hers tested the formulated product at sa me application rates as the preceding study , but applications were made during active bee foraging and at night. There were no changes in mortality after two applications of 0 .134 lb ai/A; flight activity could not be quantified because sampling occurred at variable intervals because of cold and rainy weather . For the 0.011 lb ai/A rate, mortality was not affected either, but there was a decrease in flight activity (3

bees/m 2 

### in treatment group versus 4 bees/m 2 

### in the control) through the third day after application

.

### 72 I n a study of cyantraniliprole co

- formulated with codacide oil in oilseed rape (MRID 48122558)

, t wo applications at 0.08 lb ai/A were made . The first treatment occurred before flowering and the introduction of bees into the field. The second application occurred either at night (Treatment 1) or during active bee foraging (Treatment 2)

. The second application made at night did not increase mortality; however, f oraging activity

was decreased (0 to 1 bee/m 2 

### in treatment compared to 2 to 4 bees/m 2 

### in the control) for three days after application. The second application made during bee flight resulted in a

3

- fold increase in mortality , compared with the control , for up to five days after the application. Flight activity was reduced (1 bee/m 2 

### in treatment compared to 2 to 4

bees/m 2 

### in the control) for three days after the application. The study evaluated brood and colony health up until the start of overwinteri ng (170 days after application). No

differences were noted in brood condition or colony health between the controls and

treatment groups.

Another full field study on oilseed rape with cyantraniliprole alone ( MRID 48122557 )

followed the hive through ove rwintering to the spring (323 days after treatment). Two applications of 0.08 lb ai/A were made. The first occurred before flowering and the introduction of bees into the field. The second application occurred either at night (Treatment 1) or during act ive bee foraging (Treatment 2). There was no effect on mortality for Treatment 1. Effects on mortality for Treatment 2 ( 160 dead bees/day in treatment compared to 15 dead bees/day in the control) persisted for 5 days after the second application. Flight activity was not affected for either treatment group; however, differences may have been masked by several days of bad weather. No differences were

ob served for brood condition or colony health between the control and T reatment 1 (application at night ); however, T reatment 2 (application made during bee flight) had a much smaller average size colony (5731 bees) than either T reatment 1 (15308 bees) or the control (14086 bees) at the end o f overwintering. In other words, the control colonies

increased in numbers of worker bees by roughly 102%; T reatment 1 increased by roughly

3% ; and T reatment 2 declined by roughly 37%. Comparing the numbers from the overwintered colonies to those for the colonies originally, i.e ., 1 year p e riod, the controls

and T rea tment 1 ha d increased by factors of 1.5x and 1.3x, respectively; h owever,
T reatment 2 had declined by a factor of 2.1x. T his suggests that the colonies from

T reatment 2 were not similar to Treatment 1; however, the reason for this difference is

uncertain. Several colonies died during the winter: two controls and one in each

treatment group.

A full field stud y on cyantraniliprole co

- formulated with codacide oil on melon ( Cucumis

melo ) ( MRID 48688 8 06 ) also tested two applications of 0.08 lb ai/A. For T reatment 1, applications occurred at night

– one at the start of flowering and a second application 7 days later. For Treatment 2, applications occurred at the same intervals as Treatment 1, but during active bee foraging periods. No effects were observed on mortality in Treatment 1, but Treatment 2 exhibited an increase in mortality (49 dead bees/day in Treatment 2 compared with 8 dead bees/day in the control) for up to one day after the first application, but no effects after the second. No differences were documented in foraging activity in either treatment, but bad weather conditions may have masked the

effects. At the start of the study (29 July 2011) , the mean colony sizes w ere 107 95,

### 73 10988 and 9157 honey bees in Treatment 1, Treatment 2 and the control, respectively. Colony size quickly declined in all groups over the following observation points, with the lowest mean colony size being observed at 8 September 2011 in all groups, i. e. 3709, 4141 and 1399 honey bees in Treatment 1, Treatment 2 and the control. The study attributes the decline to preparation for overwintering, but the decline occurs earlier in the season than would be expected for this explanation. It is uncertain whe ther foraging

conditions for the hives were sufficient and whether the decline was a result of limited

floral resources. Despite this decline, brood number counts after over wintering (202 days after application) were similar to those at the beginning of t he study. At the start of the study, all hives (controls and treatments) exhibited ~15% of their combs covered in brood. After overwintering, the percent of combs covered in brood were ~18% for the

controls and 23

- 26% for the treatment groups . Many of t he hives in the study were subject to v arroa mite infestation s during the course of the study

.

Another full

- field study of cyantraniliprole plus codacide oil applied to oilseed rape also

had hives that became infested with varroa mites (MRID 48122552). The study tested application rates of 0.134 and 0.011 lb ai/A. The first application was made before flowering and the introduction of bees to the field. The second application occurred during flowering at night (Treatment 1) or d uring active bee foraging (Treatment 2). An increase in mortality (84 dead bees/day in Treatment 1 compared to 12 dead bees per day in the control) persisted for one day after the second application in Treatment 1. No effects on mortality were seen in Tr eatment 2. Reductions in flight activity were also documented after the second applications of cyantraniliprole (Treatments 1 and 2 = 1

bee/m 2 

### ; control = 4 bees/m 2 

### ); effects lasted for one day after treatment. Sub

- lethal effects

included impaired locomot ion and cramping. An additional observation was that hives not exposed to cyantraniliprole (controls) appeared better able to resist the infestation than those hives that were exposed. This suggests that while cyantraniliprole may have

limited effects on honeybees by itself, when combined with other real

- world stressors, hive health may be affected. The study did not show any effects to brood development or colony strength.

Acute oral toxicity informatio n was available for three of cyantraniliprole’ s degradates ( Table 30 ) . Two of the degrada tes (IN

- HGW87 and IN

- J9Z38) may be more toxic on an

acute oral exposure basis than the parent , but given that the endpoints were non

definitive, there is uncertainty . Sub

- let hal effects (lethargic and moribund b ees) were only reported for IN

- HGW87 (MRID 481 20184). This indicates that two of the cyantraniliprole degradates should be carefully considered for their toxicological effects in addition to the parent.

Several field studies measured residues of cyantraniliprole and its degradates in pollen, honey, wax , and guttation fluid ( Table 31 ). Cyantraniliprole residues were detected in all

of the studies; however, the degradate detection was more limited. Only three degradates (IN

- J9Z38, IN

- HGW87, IN

- MYX98) were detected in guttation fluid , despite testing for a larger array of degradates across multiple food items. Of these, toxicity information is

available for IN

- J9Z38 and IN

- HGW87.

### 74 Table 29

. Summary of Honeybee Toxicity I nformation

Study Test Material Species Toxicity Endpoint (μg ai/bee) Classification and

MRID

Acute oral and contact toxicity TGAI (93.4%) Honeybee

( Apis mellifera ) Oral

48

- hr LD 50 >
0.1055

Contact

48

- hr LD 50 > 0.0934

NOAEC = 0.0234 Acceptable

48120090

Acute oral and contact toxicity TEP (10.26%) Honeybee

( Apis mellifera ) Oral

48

- hr LD 50 = 0.39

NOAEL = 0.086

Contact

48

- hr LD 50 = 1.2

NOAEL = 0.19 Acceptable

48120113

Acute oral and contact toxicity TEP (10.26%) Honeybee

( Apis mellifera ) Oral

96

- hr LD 50 = 0.92

Contact

48

- hr LD 50 = 3.03

NOAEL < 0.5 Acceptable

48120164

Acute oral and contact toxicity TEP (18.66%) Honeybee

( Apis mellifera ) Oral

96

- hr LD 50 = 0.404

NOAEL = 0.034

Contact

48

- hr LD 50 = 0.55 **

NOAEL = 0.025 Acceptable

48120137

Acute oral and contact toxicity TEP (20.6%)

Other ai

- thiamethoxam Honeybee

( Apis mellifera ) Oral

48

- hr LD 50 =

0.0062 **

Contact

48

- hr LD 50 =

0.058 ** Acceptable

48432530

Acute oral toxicity TEP (20%) Honeybee

( Apis mellifera ) Oral

48

- hr LD 50 =

0.116 ** Supplemental

48432416 TGAI = technical grade active ingredient TEP = typical end

- use product **may be considered in spray drift analysis

### 75 Table 30

. Summary of Select Cyan traniliprole Degradates to H oneybees

Study Test Material Species Toxicity Endpoint (μg/bee) Classification and

MRID

Acute oral toxicity IN

- HGW87 (74.1%) Honeybee

( Apis mellifera ) 72

- hr LD 50 = 0.298

NOAEL = 0.143 Supplemental

48120184

Acute oral toxicity IN

- HGW87 (74.1%) Honeybee

( Apis mellifera ) 48

- hr LD 50 > 0.030

NOAEL = 0.030 Supplemental

48122518

Acute oral toxicity IN

- J9Z38 (96.4%) Honeybee

( Apis mellifera ) 48

- hr LD 50 >
0.00834 Supplemental

48120185

Acute oral toxicity IN

- K5A78 (96.1%) Honeybee

( Apis mellifera ) 48

- hr LD 50 > 45.61

NOAEC = 45.61 Supplemental

48122514



### Table 31

. Summary of C yantraniliprole and Degradate C oncen trations Detected in Pollen, Nectar, Wax, G uttation Water, and H oney
Application Rate (lb ai/A) Cyantranilipr ole Residues (m g ai/kg) 1 Other Degradates (mg

ai /kg) 1 MRID

Foliar oilseed rape

2 at 0.08 (20 days) Honey = 0.013

Pollen = 0.0 19

Wax = 0.0 33

Guttation = 3

. 092

LOQ = 0.005 Guttation

IN

- J9Z38 = 0.0 4 6

IN

- HGW87 = 0.010

IN

- MYX98 = 0.008

LOQ = 0.005 48122557

Foliar oilseed rape

2 at 0.08 (16 days) Honey = 0.020

Pollen = 0.0 65

Wax = 0.0 30

Guttation = 0. 647

LOQ = 0.005 Guttation

IN

- J9Z38 = 0.0 12

IN

- HGW87 = 0.00 8

IN

- MYX98 = 0.00 7

LOQ = 0.005 48122558

Foliar oilseed rape

2 at 0.134 (15 days) Pollen (median) = 0.0 25 Honey = 0.00 5

LOQ = 0.005 Not available 48122553

Foliar oilseed rape

2 at 0.011 (15 days) Pollen (median) = 0.0 1 1

Wax = 0.008

LOQ = 0.005 Not available 48122553

Foliar oilseed rape

2 at 0.134 (17 days) Honey = 0.00 5

Pollen = 0.0 77

LOQ = 0.005 IN

- J9Z38 = 0.00 7 and 0.010

LOQ = 0.005 48122552

Foliar oilseed rape

2 at 0.011 (17 days) Pollen = 0.0 42

LOQ = 0.005 Not available 48122552

Foliar oilseed rape

2 at 0.011 (15 days) Honey (median) = 0.006

Pollen = 0.00 9

Wax = 0.0 11

LOQ = 0.005 Not available 48122551

Foliar oilseed rape Honey (median) = 0.00 8 Not available 48122551

### 76 Application Rate (lb ai/A) Cyantranilipr ole Residues (m g ai/kg) 1 Other Degradates (mg

ai /kg) 1 MRID

2 at 0.134 (15 days) Pollen = 0.0 62

Wax = 0.0 1 7

LOQ = 0.005

Drip irrigated

melon

3 at 0.089 (7 days) Pollen = 0.0 12

N ectar = 0.0 26

Guttation = 0.0 66

LOQ = 0.005 Not available 48122548

LOQ = level of quantification

1 Values reported are maximums unless otherwise stated.



### Other Terrestrial Invertebrates

Data were also available for parasit ic wasp ( Aphidius rhopalosiphi ) , predatory mites ( Typhlodromus pyri and Hypoaspis aculeifer ) , rove beetle s ( Aleochara bilineata )

, ladybird beetle s ( Coccinella septempunctata )

, green lacewing s ( Chrysoperla carnea )

, lycosid spider s ( Pardosa spp. )

, and collembolan ( Folsomia candida ) ( Table 32 )

. These

are non

- guideline studies and thus were classified as “supplemental” information.

E xtended acute toxicity studies for parasitoids were available. Several studies

determined the residue concentration ( i.e., residues on foliage) that results in 50% mortality for parasitoids (LR 50 

### ). The 48

- hr LR 50 

### values for cyantraniliprole ranged from

0.00008 to > 0.004 lb ai/A. In studies where parasitoids were exposed to various aged

residues ( MRIDs 48120188 and 48120193 )

, behavioral sub

- lethal effects were noted (moribund and lethargic wasps). A study examin ing the effects of the cyantraniliprole

thiamethoxam residues on wasps (MRID 48432419 ) found 87.5% morality ( 2 apps at 0.04 lb ai/A; 14

- day interval) and 27.5% mortali ty (2 apps at 0.004 lb ai/A; 14

- day interval) after an exposure period of 48 hours immediately (after spray had dried on the leaves) following the second application of cyantraniliprole

. In a study examining the effects of cyantraniliprole on wasp mummies ( MRID 48122519 )

, t he hatch

- rate of adults was not affected up to 0.014 lb ai/A

. Several other semi

- field studies examined the effects of cyantraniliprole on parasitism rates

. MRID 48122501 demonstrated that the parasitism rate was not affected at application rates of 0.002 lb ai/A ; whereas

, MRIDs

48208411 and 48208412 documented effects a reduction ( i.e., decreased reproduction) on parasitism rates at 0.003 to 0.016 lb ai/A.

The effects of cyantraniliprole were evaluated using rove beetles resulti ng in a n LR 50 

### >0.027 lb ai/A; no sub

- lethal effects were reported in the study . A follow

- on residue study (MRID 48208413 ) demonstrated 100% mortality when rove beetles were exposed

to 2

- day aged residues at application rates of either 1.25 lb ai/A or 0.89 lb ai/A (7

- day interval) ; however, w hen residues were aged 30 and 85 days, no effects were observed. The ladybird beetle yielded a LR 50 

### of 0.039 to 0.055 lb ai/A ; no r eproductive effects were noted. A residue study (MRID 48120199 ) showed 66.7% mortality in ladybird beetles exposed to fresh ly dried residues of cyantraniliprole (10.26%). Effects on survival and reproduction were less than 50% after 14 and 28 days of residue aging. Another aged

### 77 residue test (MRID 48120192 ) demonstra ted no mortality or reproductive effects when ladybird beetles were exposed to 14 or 28 day aged residues (2 applications at 0.134 lb ai/A, 7

- day interval) ; exposures occurred after the second application of cyantraniliprole.

Acute contact toxicity studie s were provided for the predatory mite. These studies

present various concentrations of dried residues to mites for 7 to 14 day exposure periods. The route of exposure is through physical contact. The acute contact toxicity of cyantraniliprole to predat ory mites ranged from LR 50 

### >0.205 to >0.267 lb ai/A. Contact toxicity with the cyantraniliprole

- thiamethoxam product was LR 50 

### >0.092 lb ai/A.

T oxicity was measured with the soil mite . Mites were exposed for 14 days to soil with

various concentrations of cyantraniliprole. The EC 50 

### was greater than 1000 mg ai/kg

- soil

, based on mortality and reproductive effects; no sub

- lethal effect s were reported. T oxicity

data were available for sever al degradates too (see Table 32 ). All toxicity values were

non

- defini tive, but several were lower (EC 50 

### >100 mg ai/kg

- soil) than the parent.

Several fiel d studies were available for predatory mites as well

. There was no significant reduction ( ≥ 50%) in the mite population after two cyantraniliprole applications of 0.134 lb ai/A (7

- day interval) (MRID 48120189 ) . Another mite study (MRID 48120190 )

exhibited similar results after testing the same rate with a 14

- day application interval ).

Toxicity data were available for the green lacewing. The LR 50 

### ranged from 0.198 to

0. 232 lb ai/A and a decrease in hatching rate was seen at concentrations greater than

0.154 lb ai/A. MRID 48120198 found no effects on mortality or reproduction on the day of application or 14 days later when t wo applications of 0.009 lb ai/A (7

- day interval) were applied. Another residue test (MRID 48120191 ) found no mortality or reproducti ve effects when lacewings were exposed to aged residues (2 applications at 0.134 lb ai/A, 7

- day interval). Lacewings were placed with residues that had b een aged for various periods of time and they were followed through pupation, to adult, through 7 days after

egg lying

.

A number of studies were available for collembola. An EC 50 

### was established at >1200 mg ai/kg

- soil (no sub

- lethal effects) for cyantran iliprole

. A field study ( MRID

48208453 ) showed a statistically significant (p<0.05) reduction in various species of collembola for up to 88 days after applying two applications of up to 1.25 lb ai/A (7

- day interval). Toxicity studies for degradates also were available (see entries in Table 32 ). Most of the toxicity values were non

- definitive ; therefore, it is not possible to determine the relative toxicity to the parent compound Two degradates ( IN

- QKV54 and IN

RNU71) yielded definitive toxicity values that were much more toxic than the parent (EC 50 

### = 98.3 and 20.3 mg ai/kg

- soil, respectively).

A litterbag study with micro arthropods was conducted (MRID 48208451 ) . Soil was treated with cyantraniliprole and then the microarthropods were samp led at 92 and 143 days after the treatment. The study s howed that a n application of 0.047 lb ai/A followed by an application of 0.267 lb ai/ A (11

- day interval) had no effect on the abundance of micro arthropods in the soil.

### 78 The lycosid spider yielded a LR 50 

### of >0 .356 lb ai/A with no sub

- lethal effects reported.

Table 32

. Summary of Acute and Chronic Toxicity Data for Terrestrial A rthropods

Study Test Material Species Toxicity Endpoint Classification and

MRID

Acute toxicity to parasitoid TEP (18.66%) Parasitic wasp

( Aphidius rhopalosiphi ) 48

- hr LR 50 = 0.0003 lb ai/A

48

- hr ER 50 = 0.0003 lb ai/A Supplemental

48120155

Acute toxicity to parasitoid TEP (10.26%) Parasitic wasp

( Aphidius rhopalosiphi ) 48

- hr LR 50 = 0.00009 lb ai/A Supplemental

48120130

Acute toxicity to parasitoid TEP (10.26%) Parasitic wasp

( Aphidius rhopalosiphi ) 48

- hr LR 50 = 0.00008 lb ai/A

48

- hr ER 50 > 0.0001 lb ai/A Supplemental

48120163

Extended acute toxicity to parasitoid TEP (10.26%) Parasitic wasp ( Aphidius rhopalosiphi ) 48

- hr LR 50 = 0.001

lb ai/A Supplemental

48120161

Extended acute toxicity to parasitoid TEP (10.26%) Parasitic wasp ( Aphidius rhopalosiphi ) LR 50 >0.004 lb

ai/A

ER 50 > 0.392 lb

ai/A Supplemental

48122516

Extended acute toxicity to parasitoid TEP (10.26%) Parasitic wasp

( Aphidius rhopalosiphi ) 48

- hr LR 50 = 0.002

lb ai/A

48

- hr ER 50 > 0.001

lb ai/A Supplemental

48120168

Extended acute toxicity to parasitoid TEP (10.26%) Parasitic wasp

( Aphidius rhopalosiphi ) 48

- hr LR 50 >0.002

lb ai/A

48

- hr ER 50 < 0.002

lb ai/A Supplemental

48122517

Extended acute toxicity to parasitoid TEP (20%) with

thiamethoxam (20%) Parasitic wasp

( Aphidius rhopalosiphi ) 48

- hr LR 50 = 0.0037 lb ai/A

NOAEC = 0.0001 lb ai/A (based on mortality) Supplemental

48432417

Residue toxicity to parasitoid TEP (10.26%) Parasitic wasp

( Aphidius rhopalosiphi ) Fresh

- dried

residues

48

- hr LR 50 = 0.018

lb ai/A

48

- hr ER 50 >0.017

lb ai/A

Aged residues

48

- hr ER 50 >0.017

lb ai/A Supplemental

48663805

Acute toxicity to

predatory mite TEP (10.26%) Predatory mite

( Typhlodromus pyri ) 7

- d LR 50 > 0.205

lb ai/A Supplemental

48120129

Acute toxicity to

predatory mite TEP (18.66%) Predatory mite

( Typhlodromus 7

- d LR 50 >0.205 lb

ai/A

14

- d ER 50 >0.205 Supplemental

48120154

### 79 Study Test Material Species Toxicity Endpoint Classification and

MRID

pyri ) lb ai/A

Acute toxicity to

predatory mite TEP (10.26%) Predatory mite

( Typhlodromus pyri ) 7

- d LR 50 >0.267 lb

ai/A

14

- d ER 50 >0.267

lb ai/A Supplemental

48120162

Acute contact

toxicity to predatory mite TEP (20%) with

thiamethoxam Predatory mite

( Typhlodromus pyri ) 7

- day LR 50 >0.091

lb ai/A

NOAEC = 0.091

lb ai/A Supplemental

48432418

Reproduction

effects on predatory mite TGAI (94.5%) Predatory mite

( Hypoaspis aculeifer ) 14

- day EC 50 > 1000 mg ai/kg

- soil

14

- day LC 50 > 1000 mg ai/kg

- soil

NOAEC = 1000

mg ai/kg

- soil Supplemental

48120183

Reproduction

effects on predatory mite Degradate IN

J9Z38 (97.2%) Predatory mite

( Hypoaspis aculeifer ) 14

- day LC 50 > 1000 mg IN

J9Z38/kg

- soil

14

- day EC 50 > 1000 mg IN

J9Z38/kg

- soil

NOAEC = 1000 mg IN

- J9Z38/kg

soil Supplemental

48122511

Reproduction

effects on predatory mite Degradate IN

JCZ38 (94.4%) Predatory mite

( Hypoaspis aculeifer ) 14

- day LC 50 > 1000 mg IN

JCZ38/kg

- soil

14

- day EC 50 > 1000 mg IN

JCZ38/kg

- soil

NOAEC = 1000 mg IN

- JCZ38/kg

soil Supplemental

41822504

Reproduction

effects on predatory mite Degradate IN

JSE76 (93.8%) Predatory mite

( Hypoaspis aculeifer ) 14

- day LC 50 > 1000 mg IN

JSE76/kg

- soil

14

- day EC 50 > 1000 mg IN

JSE76/kg

- soil

NOAEC = 1000 mg IN

- JSE76/kg

soil Supplemental

48122510

Reproduction

effects on predatory mite Degradate IN

K5A77 (92.3%) Predatory mite

( Hypoaspis aculeifer ) 14

- day LC 50 > 1000 mg IN

K5A77/kg

- soil

14

- day EC 50 > 1000 mg IN

K5A77/kg

- soil

NOAEC = 1000 mg IN

- K5A77/kg

soil Supplemental

48120197

Reproduction

effects on Degradate IN

K5A78 (96.5%) Predatory mite 14

- day LC 50 > 1000 mg IN

Supplemental

### 80 Study Test Material Species Toxicity Endpoint Classification and

MRID
predatory mite ( Hypoaspis aculeifer ) K5A78/kg

- soil

14

- day EC 50 > 1000 mg IN

K5A78/kg

- soil

NOAEC = 1000 mg IN

- K5A78/kg

soil 48122507

Reproduction

effects on predatory mite Degradate IN

K5A79 (84.4%) Predatory mite

( Hypoaspis aculeifer ) 14

- day LC 50 > 1000 mg IN

K5A79/kg

- soil

14

- day EC 50 > 1000 mg IN

K5A79/kg

- soil

NOAEC = 1000 mg IN

- K5A79/kg

soil Supplemental

48122506

Reproduction

effects on predatory mite Degradate IN

PLT97 (87.0%) Predatory mite

( Hypoaspis aculeifer ) 14

- day LC 50 > 1000 mg IN

PLT97/kg

- soil

14

- day EC 50 > 1000 mg IN

PLT97/kg

- soil

NOAEC = 1000 mg IN

- PLT97/kg

soil Supplemental

48120196

Reproduction

effects on predatory mite Degradate IN

QKV54 (98.1%) Predatory mite

( Hypoaspis aculeifer ) 14

- day EC 50 >100 mg IN

- QKV54/kg

soil NOAEC = 100 mg

IN

- QKV54/kg

- soil Supplemental

48208415

Reproduction

effects on predatory mite Degradate IN

RNU71 (92.4%) Predatory mite

( Hypoaspis aculeifer ) 14

- day EC 50 > 100 mg IN

- RNU71/kg

soil NOAEC = 100 mg

IN

- RNU71/kg

- soil Supplemental

48208414

Acute toxicity to

beetle TEP (18.66%) Rove beetle ( Aleochara

bilineata ) LR 50 > 0.027 lb

ai/A

ER 50 = 0.05 lb ai/A Supplemental

48120165

Acute toxicity to

beetle TEP (10.26%) Ladybird beetle

( Coccinella

septempunctata ) 12

- day LR 50 = 0.055 lb ai/A Supplemental

48120160

Extended laboratory test on

ladybird beetle TEP (10.26%) Ladybird beetle

( Coccinella

septempunctata ) 12

- day LR 50 = 0.039 lb ai/A Supplemental

48120170

Extended toxicity to green lacewing TEP (10.26%) Green lacewing

( Chrysoperla

carnea ) 12

- day LR 50 = 0.232 lb ai/A Supplemental

48120159

Extended toxicity to green lacewing TEP (10.26%) Green lacewing

( Chrysoperla 12

- day LR 50 = 0.189 lb ai/A Supplemental

48120169

### 81 Study Test Material Species Toxicity Endpoint Classification and

MRID

carnea )

Acute toxicity to spider TEP (18.66%) Lycosid spider

( Pardosa spp. ) 14

- day LR 50 > 0.356 lb ai/A Supplemental

48120166

Extended toxicity

to collembola TGAI ( 94.5%) Collembola

( Folsomia

candida ) 28

- day EC 50 > 1200 mg/kg

- soil

NOAEC 0.0800 mg/kg

- soil Supplemental

48122530

Extended toxicity

to collembola Degradate IN

J9Z38 (97.2%) Collembola

( Folsomia

candida ) 28

- day LC 50 > 1000 mg IN

J9Z38/kg

- soil

28

- day EC 50 > 1000 mg IN

J9Z38/kg

- soil NOAEC = 500 mg

IN

- J9Z38/kg

- soil (based on mortality) Supplemental

48122512

Extended toxicity

to collembola Degradate IN

JCZ38 (94.4%) Collembola

( Folsomia

candida ) 28

- day LC 50 > 48 mg IN

- JCZ38/kg

soil

28

- day EC 50 = 47.25 mg IN

JCZ38/kg

- soil NOAEC = 12 mg

IN

- JCZ38/kg

- soil (based on reproduction) Supplemental

48122505

Extended toxicity

to collembola Degradate IN

JSE76 (93.8%) Collembola

( Folsomia

candida ) 28

- day LC 50 > 250 mg IN

- JSE76/kg

soil

28

- day EC 50 > 250 mg IN

- JSE76/kg

soil NOAEC = 250 mg

IN

- JSE76/kg

- soil Supplemental

48122513

Extended toxicity

to collembola Degradate IN

K5A77 (92.3%) Collembola

( Folsomia

candida ) 28

- day LC 50 > 1000 mg IN

K5A77/kg

- soil

28

- day EC 50 > 1000 mg IN

K5A77/kg

- soil

NOAEC < 62.5 mg IN

- K5A77/kg

soil (based on mortality and reproduction) Supplemental

48120194

Extended toxicity

to collembola Degradate IN

K5A78 (96.5%) Collembola

( Folsomia

candida ) 28

- day LC 50 > 1000 mg IN

K5A78/kg

- soil

28

- day EC 50 > 1000 mg IN

K5A78/kg

- soil Supplemental

48122509

### 82 Study Test Material Species Toxicity Endpoint Classification and

MRID

NOAEC = 1000 mg IN

- K5A78/kg

soil

Extended toxicity

to collembola Degradate IN

K5A79 (84.4%) Collembola

( Folsomia

candida ) 28

- day LC 50 >125 mg IN

- K5A79/kg

soil

28

- day EC 50 > 125 mg IN

- K5A79/kg

soil NOAEC = 125 mg

IN

- K5A79/kg

- soil Supplemental

48122508

Extended toxicity

to collembola Degradate IN

PLT97 (87.0%) Collembola

( Folsomia

candida ) 28

- day LC 50 > 1000 mg IN

PLT97/kg

- soil

28

- day EC 50 > 1000 mg IN

PLT97/kg

- soil

NOAEC = 1000 mg IN

- PLT97/kg

soil Supplemental

48120195

Extended toxicity

to collembola Degradate IN

QKV54 (98.3%) Collembola

( Folsomia

candida ) 28

- day EC 50 = 98.3

IN

- QKV54/kg

- soil

NOAEC = 98.3

IN

- QKV54/kg

- soil Supplemental

48122573

Extended toxicity

to collembola Degradate IN

RNU71 (92.4%) Collembola

( Folsomia

candida ) 28

- day LC 50 = 20.3 mg IN

- RNU71/kg

soil

28

- day EC 50 = 18.77 mg IN

RNU71/kg

- soil

NOAEC = 12.5 mg IN

- RNU71/kg

soil (based on reproduction) Supplemental

48122574

TEP = typical end

- use product TGAI = technical grade active ingredient



### Earthworms

Several studies measured the acute toxicity of cyantranil i prole and its typical end

- use products to earthworms ( Eisenia fetida ; Table 33 )

. The LC 50 

### value s were all non

definitive and ranged from >102.6 to >1030 mg ai/kg

- soil

, including formulations with

thiamethoxam . The only sub

- lethal effect observ ed was biomass loss in the cyantraniliprole

- thiamethoxam product. Two reproduction studies with TGAI showed the NOAEC to be the highest dose tested (956 mg ai/kg

- soil); tests with TEP resulted in a

NOAEC of 102.6 mg ai/kg

- soil . No adverse effects were ob served on earthworms using

either the TGAI or TEP at the maximum soil concentrations tested

. Degradates were also

tested for their acute and reproductive/growth toxicity. All endpoints were non

definitive and again, no adverse effects were observed at t he highest soil concentrations

tested

.

### 83 Table 3 3

. Summary of Toxicity Data for Earthworms

Study Test Material Species Toxicity Endpoint Classification and

MRID

Acute toxicity to

earthworm TGAI (94.5%) Earthworm

( Eisenia fetida ) 14

- day LC 50 > 945 mg ai/kg

- soil NOAEC = 945 mg ai/kg

- soil Acceptable

48120158

Acute toxicity to

earthworm TEP (18.66%) Earthworm

( Eisenia fetida ) 14

- day LC 50 >186.6 mg ai/kg

soil

NOAEC = 186.6

mg ai/kg

- soil Acceptable

48120322

Acute toxicity to

earthworm TEP (10.26%) Earthworm

( Eisenia fetida ) 14

- day LC 50 >102.6 mg ai/kg

soil

NOAEC = 102.6

mg ai/kg

- soil Acceptable

48120219

Acute toxicity to

earthworm TEP (40.7%) Earthworm

( Eisenia fetida ) 14

- day LC 50 >1017.5 mg ai/kg

soil

NOAEC = 1017.5

mg ai/kg

- soil Acceptable

48432420

Acute toxicity to

earthworm TEP (20.6%) with

thiamethoxam Earthworm

( Eisenia fetida ) 14

- day LC 50 >1030 mg ai/kg

- soil

NOAEC = 128.8

mg ai/kg

- soil Acceptable

48432531

Reproduction and growth effects on

earthworm TGAI (94.5%) Earthworm

( Eisenia fetida ) 56

- day NOAEC = 945 mg ai/kg

- soil

Based on no mortality or changes in growth and reproduction. Supplemental

48120167

Reproduction and growth effects on

earthworm TEP (10.26%) Earthworm

( Eisenia fetida ) 28

- day LC 50 > 102.6 mg ai/kg

soil

56

- day NOAEC =

102.6 mg ai/kg

soil

Based on no mortality or changes in growth and reproduction. Supplemental

48120216

Degradates

Acute toxicity to

earthworm Degradate IN

J9Z38 (96.4%) Earthworm

( Eisenia fetida ) 14

- day LC 50 > 964 mg IN

- J9Z38/kg

soil NOAEC = 964 mg

IN

- J9Z38/kg

- soil Acceptable

48120122

Acute toxicity to

earthworm Degradate IN

JCZ38 (92.1%) Earthworm

( Eisenia fetida ) 14

- day LC 50 > 921 mg IN

- JCZ38/kg

soil Acceptable

48120123

### 84 Study Test Material Species Toxicity Endpoint Classification and

MRID
NOAEC = 921 mg

IN

- JCZ38/kg

- soil

Acute toxicity to

earthworm Degradate IN

JSE76 (93.8%) Earthworm

( Eisenia fetida ) 14

- day LC 50 > 938 mg IN

- JSE76/kg

soil NOAEC = 938 mg

IN

- JSE76/kg

- soil Acceptable

48120144

Acute toxicity to

earthworm Degradate IN

K5A77 (95.3%) Earthworm

( Eisenia fetida ) 14

- day LC 50 > 953 mg IN

- K5A77/kg

soil NOAEC = 953 mg

IN

- K5A77/kg

- soil Acceptable

48120126

Acute toxicity to

earthworm Degradate IN

K5A78 (94.9%) Earthworm

( Eisenia fetida ) 14

- day LC 50 > 949 mg IN

- K5A78/kg

soil NOAEC = 949 mg

IN

- K5A78/kg

- soil Acceptable

48120141

Acute toxicity to

earthworm Degradate IN

K5A79 (84.4%) Earthworm

( Eisenia fetida ) 14

- day LC 50 > 844 mg IN

- K5A79/kg

soil NOAEC = 844 mg

IN

- K5A79/kg

- soil Acceptable

48120150

Acute toxicity to

earthworm Degradate IN

PLT97 (87.0%) Earthworm

( Eisenia fetida ) 14

- day LC 50 > 870 mg IN

- PLT97/kg

soil NOAEC = 870 mg

IN

- PLT97/kg

- soil Acceptable

48120149

Reproduction and growth effects on

earthworm Degradate IN

J9Z38 (97.2%) Earthworm

( Eisenia fetida ) 56

- day NOAEC = 1000 mg IN

J9Z38/kg

- soil

Based on no mortality or changes in growth and reproduction. Supplemental

48120176

Reproduction and growth effects on

earthworm Degradate IN

JCZ38 (94.4%) Earthworm

( Eisenia fetida ) 56

- day NOAEC = 1000 mg IN

JCZ38/kg

- soil

Based on no mortality or changes in growth and reproduction. Supplemental

48120180

Reproduction and growth effects on

earthworm Degradate IN

JSE76 (93.8%) Earthworm

( Eisenia fetida ) 56

- day NOAEC = 938 mg IN

JSE76/kg

- soil

Based on no mortality or changes in growth and reproduction. Supplemental

48120181

Reproduction and growth effects on Degradate IN

K5A77 (92.3%) Earthworm 56

- day NOAEC = 923 mg IN

Supplemental

### 85 Study Test Material Species Toxicity Endpoint Classification and

MRID

earthworm ( Eisenia fetida ) K5A77/kg

- soil

Based on no mortality or changes in growth and reproduction. 48120182

Reproduction and growth effects on

earthworm Degradate IN

K5A78 (96.5%) Earthworm

( Eisenia fetida ) 56

- day NOAEC = 1000 mg IN

K5A78/kg

- soil

Based on no mortality or changes in growth and reproduction. Supplemental

48120179

Reproduction and growth effects on

earthworm Degradate IN

K5A79 (84.4%) Earthworm

( Eisenia fetida ) 56

- day NOAEC = 1000 mg IN

K5A79/kg

- soil

Based on no mortality or changes in growth and reproduction. Supplemental

48120178

Reproduction and growth effects on

earthworm Degradate IN

PLT97 (87.0%) Earthworm

( Eisenia fetida ) 56

- day NOAEC =

1000 IN

PLT97/kg

- soil

Based on no mortality or changes in growth and reproduction. Supplemental

48120177

Reproduction and growth effects on

earthworm Degradate IN

QKV54 (98.3%) Earthworm

( Eisenia fetida ) 28

- day LC 50 > 98.3 mg IN

- QKV54/kg

soil

56

- day NOAEC = 98.3 mg IN

QKV54/kg

- soil

Based on no mortality or changes in growth and reproduction. Supplemental

48122520

Reproduction and growth effects on

earthworm Degradate IN

RNU71 (92.4%) Earthworm

( Eisenia fetida ) 28

- day LC 50 > 92.4 mg IN

- RNU71/kg

soil

56

- day NOAEC = 92.4 mg IN

RNU71/kg

- soil

Based on no mortality or changes in growth and reproduction Supplemental

48122522

TEP = typical end

- use product

### 86 Study Test Material Species Toxicity Endpoint Classification and

MRID
TGAI = technical grade active ingredient



### b. Terrestrial Plants

Results of the seedling emergence and vegetative vigor studies of various monocotyledonous and dicotyledonous plants used in agriculture indicated that the EC 25 

### value s are great er than the maximum application rate tested , i.e., EC 25 

### >0.134 lbs ai/A ( Table 34 ) using the technical end

- product containing 10.26% active ingredient

. The application rate of 0 .134 lb ai/A used in the studies is one of the single maximum application rate s proposed for use for many of the ag ricultural crops. The monocot

NOAEC in vegetative vigor study ( MRID 48120186 ) was based on decreased plant height. None of the other endpoints measured in the study had statistically significant

differences from controls. The “supplemental” studies are classified as such because the controls of several of the species in each study failed to meet germination requirements or exhibited visual signs of ill

- health. Only endpoints from species that had controls that performed well are considered in this risk assessment.

Table 34 . Summary of Toxicity Data for Terrestrial Plants

Study Test Material Species Toxicity Endpoint (lb ai/A) Classification and

MRID

Seedling

emergence test TEP (10.26%) Corn ( Zea mays ),

C ucumber ( Cucumis sativa ), oilseed rape ( Brassica napus ), soybean ( Glycine

max ), Monocot (corn)

EC 25 >0.134

NOAEC = 0.134 *

Dicot (all others)

EC 25 >0.134

NOAEC = 0.134 * Supplemental

48122575

Vegetative vigor

test TEP (10.26%) Corn ( Zea mays ), oat ( Avena sativa ), ryegrass ( Lolium

perenne )

Oilseed rape ( Brassica napus ), pea ( Pisum

sativum ), soybean

( Glycine max ) Monocot (all )

EC 25 >0.134

Dicot (all)

EC 25 >0.134 Supplemental

48120173

Vegetative vigor

test TEP (10.26%) Onion ( Allium

cepa )

Cucumber ( Cucumis sativa ), sugar beet ( Beta vulgaris ) Monocot (onion)

EC 25 >0.134

NOAEC = 0.067*

Dicot (cucumber, sugar beet)

EC 25 >0.134

NOAEC = 0.134* Acceptable

48120186

TEP

– typical end

- use product *denotes endpoint used in risk quotient calculations

### 87 IV. Risk Characterization

A. Risk Estimation

- Integration of Exposure and Effects Data

Toxicity data and exposure estimates discussed in the preceding sections are used to evaluate the potential for adverse ecological effects on non

- target species. For this screening

- level assessme nt of cyantraniliprole , the deterministic risk quotient (RQ) method is used to provide a metric of potential risks. The RQ is a comparison of exposure estimates to toxicity endpoints; EECs are divided by acute and chronic toxicity values. The resulting u nit less RQs are then compared to the Agency’s levels of concern (LOCs) (see Appendix H ) , which are the Agency’s interpretive policy such that when LOCs are exceeded, the need for regulatory action may be considered. The LOCs are used to indicate when the use of a pesticide, as directed on the label, has the potential to

cause adverse effects on non

- target organisms.

1. Non

- target Aquatic Animals and Plants

Aquatic Animals

Cyantraniliprole is classified as “ slightly to moderately toxic” to freshwater fish on an acute exposure basis . Only non

- definitive data were available for cyantraniliprole TGAI

, thus ris k quotients were not calculated. Toxicity tests with TEP yield ed definitive toxicity values that were more sensitive than cyantranilipr ole TGAI , but these will be

discussed in the R isk Description section. Risk quotients calculated for chronic exposures to cyantraniliprole ranged from <0.001 to 0.003 and were all well below the

chronic risk to listed and non

- listed species LOC of 1. The refore, the likelihood of

adverse effects to freshwater fish and by extension to aquatic

- phase amphibians for which freshwater fish serve as surroga tes from chronic exposure to cy a n traniliprole is

considered low ( Table 35 ).

Cyantraniliprole is classified as “slightly toxic” to estuarine/marine fish on an acute exposure basis . Chronic and acute toxicity data were non

- definitive, thus risk quotients were not calculated. A further description of the acute and chr onic risks can be found in

the R isk Descripti on section. Therefore, the likelihood of adverse effects from either acute or chronic exposure to cyantraniliprole is considered low.

Table 3 5

. RQs for Chronic Freshwater F ish (Based on Surface W ater EECs)

Uses /Application Rate 60

- day

EEC (μg/L) Freshwater

Fish Chronic RQ *

Brassica vegetable

- 1 app at 0.4 lb ai/A (C) 22.19 0.002
Brassica leafy vegetable

– 2 apps at 0.175 lb ai/A and 1 app at 0.05 lb ai/A (7 days) (A) 20.66 0.002

Brassica leafy vegetable

– 2 apps at 0.175 lb ai/A and 1 app at 0.05 lb ai/A (7 days) (G) 16.75 0.002

Brassica leafy vegetables

– 3 apps at 0.133 lb ai/A (5 days) (A) 16.64 0.002

### 88 Uses /Application Rate 60

- day

EEC (μg/L) Freshwater

Fish Chronic RQ *

Brassica leafy vegetables

– 3 apps at 0.133 lb ai/A (5 days) (G) 12.65 0.001

Bushberries

– 3 apps at 0.133 lb ai/A (5 days) (A) 13.17 0.001

Bushberries

– 3 apps at 0.133 lb ai/A (5 days) (G) 8.64 0.001

Citrus

– 3 apps at 0.133 lb ai/A (7 days) (A) 15.30 0.001

Citrus

– 3 apps at 0.133 lb ai/A (7 days) (G) 13.34 0.001

Citrus

– 1 app at 0.4 lb ai/A (C) 9.98 0.001

Cotton

– 3 apps at 0.133 lb ai/A (7 days) (A) (CA cotton) 8.98 0.001

Cotton

– 3 apps at 0.133 lb ai/A (7 days) (G) (CA cotton) 5.96 0.001

Cotton

– 3 apps at 0.133 lb ai/A (7 days) (A) (MS cotton) 28.50 0.003

Cotton

– 3 apps at 0.133 lb ai/A (7 days) (G) (MS cotton) 26.44 0.002

Cotton

– 3 apps at 0.133 lb ai/A (7 days) (A) (NC cotton) 37.42 0.003

Cotton

– 3 apps at 0.133 lb ai/A (7 days) (G) (NC cotton) 35.06 0.003

Cucurbits

– 2 apps at 0.175 lb ai/A and 1 app at 0.05 lb ai/A (5 days) (A) 31.82 0.003

Cucurbits

– 2 apps at 0.175 lb ai/A and 1 app at 0.05 lb ai/A (5 days) (G) 30.57 0.003

Cucurbits

– 2 apps at 0.13 lb ai/A (10 days) (C) 4.21 <0.001

Cucurbits

– 1 app at 0.4 lb ai/A (C) 7.91 0.001
Fruiting vegetables

– 2 apps at 0.175 lb ai/A and 1 app at 0.05 lb ai/A (5 days) (A) (FL peppers) 14.56 0.001

Fruiting vegetables

– 2 apps at 0.175 lb ai/A and 1 app at 0.05 lb ai/A (5 days) (G) (FL peppers) 12.65 0.001

Fruiting vegetables

– 2 apps at 0.175 lb ai/A and 1 app at 0.05 lb ai/A (5 days) (A) (CA tomato) 15.50 0.001

Fruiting vegetables

– 2 apps at 0.175 lb ai/A and 1 app at 0.05 lb ai/A (5 days) (G) (CA tomato) 12.70 0.001

Fruiting vegetables

– 2 apps at 0.175 lb ai/A and 1 app at 0.05 lb ai/A (5 days) (A) (FL tomato) 24.67 0.002

Fruiting vegetables

– 2 apps at 0.175 lb ai/A and 1 app at 0.05 lb ai/A (5 days) (G) (FL tomato) 23.10 0.002

Fruiting vegetables

– 2 apps at 0.175 lb ai/A and 1 app at 0.05 lb ai/A (5 days) (A) (PA tomato) 27.95 0.003

Fruiting vegetables

– 2 apps at 0.175 lb ai/A and 1 app at 0.05 lb ai/A (5 days) (G) (PA tomato) 24.71 0.002

Fruiting vegetables

– 2 apps at 0.13 lb ai/A (5 days) (C) (FL peppers) 4.38 <0.001

Fruiting vegetables

– 2 apps at 0.13 lb ai/A (5 days) (C) (CA tomato) 1.40 <0.001

Fruiting vegetables

– 2 apps at 0.13 lb ai/A (5 days) (C) (FL tomato) 9.78 0.001

### 89 Uses /Application Rate 60

- day

EEC (μg/L) Freshwater

Fish Chronic RQ *

Fruiting vegetables

– 2 apps at 0.13 lb ai/A (5 days) (C) (PA tomato) 12.43 0.001

Fruiting vegetables

– 1 app at 0.4 lb ai/A (C) (FL peppers) 25.00 0.002

Fruiting vegetables

– 1 app at 0.4 lb ai/A (C) (CA tomato) 0.27 <0.001

Fruiting vegetables

– 1 app at 0.4 lb ai/A (C) (FL tomato) 16.08 0.002

Fruiting vegetables

– 1 app at 0.4 lb ai/A (C) (PA tomato) 10.87 0.001

Leafy vegetables

– 1 app at 0.4 lb ai/A (C) 15.30 0.001
Leafy vegetables

– 2 apps at 0.175 lb ai/A and 1 app at 0.05 lb ai/A (7 days) (A) 14.02 0.001

Leafy vegetables

– 2 apps at 0.175 lb ai/A and 1 app at 0.05 lb ai/A (7 days) (G) 10.22 0.001

Leafy vegetables (except brassica)

– 3 apps at 0.133 lb ai/A (5 days) (A) 10.69 0.001

Leafy vegetables (except brassica)

– 3 apps at 0.133 lb ai/A (5 days) (G) 6.71 0.001

Oil seeds

– 3 apps at 0.133 lb ai/A (7 days) (A) (ND canola) 22.02 0.002

Oil seeds

– 3 apps at 0.133 lb ai/A (7 days) (G) (ND canola) 17.97 0.002

Oil seeds

– 3 apps at 0.133 lb ai/A (7 days) (A) (ND wheat) 25.24 0.002

Oil seeds

– 3 apps at 0.133 lb ai/A (7 days) (G) (ND wheat) 21.40 0.002

Pome fruit

– 3 apps at 0.133 lb ai/A (7 days) (A) (CA fruit) 4.93 <0.001

Pome fruit

– 3 apps at 0.133 lb ai/A (7 days) (G) (CA fruit) 1.61 <0.001

Pome fruit

– 3 apps at 0.133 lb ai/A (7 days) (A) (NC apple) 19.54 0.002

Pome fruit

– 3 apps at 0.133 lb ai/A (7 days) (G) (NC apple) 16.07 0.002

Pome fruit

– 3 apps at 0.133 lb ai/A (7 days) (A) (OR apple) 12.63 0.001

Pome fruit

– 3 apps at 0.133 lb ai/A (7 days) (G) (OR apple) 8.35 0.001

Pome fruit

– 3 apps at 0.133 lb ai/A (7 days) (A) (PA apple) 14.07 0.001

Pome fruit

– 3 apps at 0.133 lb ai/A (7 days) (G) (PA apple) 10.73 0.001

Potatoes

– 1 app at 0.69 lb ai/A (S) (ID potato) 6.45 0.001

Potatoes

– 1 app at 0.69 lb ai/A (S) (ME potato) 8.77 0.001

Potatoes

– 1 app at 0.176 lb ai/A (S) (ID potato) 1.65 <0.001

Potatoes

– 1 app at 0.176 lb ai/A (S) (ME potato) 2.24 <0.001
Corm and tuberous vegetables

– 3 apps at 0.133 lb ai/A (5 days) (A) (ID potato) 18.98 0.002

### 90 Uses /Application Rate 60

- day

EEC (μg/L) Freshwater

Fish Chronic RQ *

Corm and tuberous vegetables

– 3 apps at 0.133 lb ai/A (5 days) (G) (ID potato) 14.32 0.001

Corm and tuberous vegetables

– 3 apps at 0.133 lb ai/A (5 days) (A) (ME potato) 25.33 0.002

Corm and tuberous vegetables

– 3 apps at 0.133 lb ai/A (5 days) (G) (ME potato) 20.41 0.002

Corm and tuberous vegetables

- 1 app at 0.25 lb ai/A (C) (ID potato) 6.85 0.001

Corm and tuberous vegetables

- 1 app at 0.25 lb ai/A (C) (ME potato) 10.60 0.001

Rapeseed including canola varieties, mustard

seed

– 1 app at 0.4 lb ai/A (S) (ND canola) 19.61 0.002

Rapeseed including canola varieties, mustard

seed

– 1 app at 0.4 lb ai/A (S) (ND wheat) 36.26 0.003

Stone fruit

– 3 apps at 0.133 lb ai/A (7 days) (A) (MI cherry) 18.74 0.002

Stone fruit

– 3 apps at 0.133 lb ai/A (7 days) (G) (MI cherry) 14.07 0.001

Stone fruit

– 3 apps at 0.133 lb ai/A (7 days) (A) (GA peaches) 5.91 0.001

Stone fruit

– 3 apps at 0.133 lb ai/A (7 days) (G) (GA peaches) 3.28 <0.001

Stone fruit

– 3 apps at 0.133 lb ai/A (7 days) (A) (CA fruit) 5.90 0.001

Stone fruit

– 3 apps at 0.133 lb ai/A (7 days) (G) (CA fruit) 3.07 <0.001

Sunflower

– 1 app at 0.016 lb ai/A (S) (ND canola) 0.45 <0.001

Sunflower

– 1 app at 0.016 lb ai/A (S) (ND wheat) 0.84 <0.001

Tree nuts

– 3 apps at 0.133 lb ai/A (A) (CA almonds) 10.87 0.001

Tree nuts

– 3 apps at 0.133 lb ai/A (G) (CA almonds) 8.35 0.001

Tree nuts

– 3 apps at 0.133 lb ai/A (A) (GA pecans) 19.01 0.002

Tree nuts

– 3 apps at 0.133 lb ai/A (G) (GA pecans) 16.94 0.002

Bulb vegetables

– 3 apps at 0.133 lb ai/A (5 days) (A) (CA onion) 5.77 0.001

Bulb vegetables

– 3 apps at 0.133 lb ai/A (5 days) (G) (CA onion) 3.03 <0.001

Bulb vegetables

– 3 apps at 0.133 lb ai/A (5 days) (A) (GA onion) 20.11 0.002

Bulb vegetables

– 3 apps at 0.133 lb ai/A (5 days) (G) (GA onion) 17.76 0.002

Flowerbeds and ground covers

– 2 apps at 0.208 lb ai/A (7 days) (G) (CA nursery) 2.59 <0.001

Flowerbeds and ground covers

– 2 apps at 0.208 lb ai/A (7 days) (G) (FL nursery) 16.65 0.002

Flowerbeds and ground covers

– 2 apps at 0.208 15.98 0.001

### 91 Uses /Application Rate 60

- day

EEC (μg/L) Freshwater

Fish Chronic RQ *

lb ai/A (7 days) (G) (MI nursery)

Flowerbeds and ground covers

– 2 apps at 0.208 lb ai/A (7 days) (G) (NJ nursery) 13.84 0.001

Flowerbeds and ground covers

– 2 apps at 0.208 lb ai/A (7 days) (G) (OR nursery) 4.18 <0.001

Flowerbeds and ground covers

– 2 apps at 0.208 lb ai/A (7 days) (G) (TN nursery) 11.91 0.001

Ornamentals treated by commercial and consumer applicators

– 2 apps at 0.13 lb ai/A (7 days) (G) (CA nursery) 3.30 <0.001

Ornamentals treated by commercial and consumer applicators

– 2 apps at 0.13 lb ai/A (7 days) (G) (FL nursery) 9.77 0.001

Ornamentals treated by commercial and consumer applicators

– 2 apps at 0.13 lb ai/A (7 days) (G) (MI nursery) 9.98 0.001

Ornamentals treated by commercial and consumer applicators

– 2 apps at 0.13 lb ai/A (7 days) (G) (NJ nursery) 8.64 0.001

Ornamentals treated by commercial and consumer applicators

– 2 apps at 0.13 lb ai/A (7 days) (G) (OR nursery) 2.61 <0.001

Ornamentals treated by commercial and consumer applicators

– 2 apps at 0.13 lb ai/A (7 days) (G) (TN nursery) 7.43 0.001

Ornamental plants, fruit and nut trees (non

bearing) and forest seedlings grown in greenhouses, lath and shade houses, containers, field nurseries and interiorscapes

– 2 apps at 0.13 lb ai/A (14 days) (CA nursery) 3.33 <0.001

Ornamental plants, fruit and nut trees (non

bearing) and forest seedlings grown in greenhouses, lath and shade houses, containers, field nurseries and interiorscapes

– 2 apps at 0.13 lb ai/A (14 days) (FL nursery) 6.58 0.001

Ornamental plants, fruit and nut trees (non

bearing) and forest seedlings grown in greenhouses, lath and shade houses, containers, field nurseries and interiorscapes

– 2 apps at 0.13 lb ai/A (14 days) (MI nursery) 10.11 0.001

Ornamental plants, fruit and nut trees (non

bearing) and forest seedlings grown in greenhouses, lath and shade houses, containers, field nurseries and interiorscapes

– 2 apps at 0.13 lb ai/A (14 days) (NJ nursery) 8.91 0.001

Ornamental plants, fruit and nut trees (non

bearing) and forest seedlings grown in greenhouses, lath and shade houses, containers, field nurseries and interiorscapes

– 2 apps at 0.13 lb ai/A (14 days) (OR nursery) 2.68 <0.001

Ornamental plants, fruit and nut trees (non

- 7.44 0.001

### 92 Uses /Application Rate 60

- day

EEC (μg/L) Freshwater

Fish Chronic RQ *

bearing) and forest seedlings grown in greenhouses, lath and shade houses, containers, field nurseries and interiorscapes

– 2 apps at 0.13 lb ai/A (14 days) (TN nursery) Ornamental plants, fruit and nut trees (non

bearing) and forest seedlings grown in

gree nhouses, lath and shade houses, containers, field nurseries and interiorscapes

– 2 apps at 0.13 lb ai/A (14 days) (C) (CA nursery) 0.40 <0.001

Ornamental plants, fruit and nut trees (non

bearing) and forest seedlings grown in greenhouses, lath and shade h ouses, containers, field nurseries and interiorscapes

– 2 apps at 0.13 lb ai/A (14 days) (C) (FL nursery) 3.50 <0.001

Ornamental plants, fruit and nut trees (non

bearing) and forest seedlings grown in greenhouses, lath and shade houses, containers,

field nurseries and interiorscapes

– 2 apps at 0.13 lb ai/A (14 days) (C) (MI nursery) 7.55 0.001

Ornamental plants, fruit and nut trees (non

bearing) and forest seedlings grown in greenhouses, lath and shade houses, containers, field nurseries and interiorscap es

– 2 apps at 0.13 lb ai/A (14 days) (C) (NJ nursery) 5.82 <0.001

Ornamental plants, fruit and nut trees (non

bearing) and forest seedlings grown in greenhouses, lath and shade houses, containers, field nurseries and interiorscapes

– 2 apps at 0.13

lb ai/A (14 days) (C) (OR nursery) 1.47 <0.001

Ornamental plants, fruit and nut trees (non

bearing) and forest seedlings grown in greenhouses, lath and shade houses, containers, field nurseries and interiorscapes

– 2 apps at 0.13 lb ai/A (14 days) (C) (TN nu rsery) 6.75 0.001

Ornamental plants (exterior landscapes and interior plantscapes)

– 1 app at 0.42 lb ai/A (G) (CA nursery) 5.84 0.001

Ornamental plants (exterior landscapes and interior plantscapes )

– 1 app at 0.42 lb ai/A (G) (FL nursery) 9.90 0.001

Ornamental plants (exterior landscapes and interior plantscapes)

– 1 app at 0.42 lb ai/A (G) (MI nursery) 16.03 0.001

Ornamental plants (exterior landscapes and interior plantscapes )

– 1 app at 0.42 lb ai/A (G) (NJ nursery) 18.25 0.002

Ornamental plants (exterior landscapes and interior plantscapes )

– 1 app at 0.42 lb ai/A (G) (OR nursery) 4.15 <0.001

Ornamental plants (exterior landscapes and interior plantscapes)

– 1 app at 0.42 lb ai/A (G) 10.40 0.001

### 93 Uses /Application Rate 60

- day

EEC (μg/L) Freshwater

Fish Chronic RQ *

(TN nursery)

Ornamental plants (exterior landscapes and interior plantscapes)

– 1 app at 0.42 lb ai/A (C) (CA nursery) 1.26 <0.001

Ornamental plants (exterior landscapes and interior plantscapes )

– 1 app at 0.42 lb ai/A (C) (FL nursery) 6.11 0.001

Ornamental plants (exterior landscapes and interior plantscapes)

– 1 app at 0.42 lb ai/A (C) (MI nursery) 13.02 0.001

Ornamental plants (exterior landscapes and interior plantscapes )

– 1 app at 0.42 lb ai/A (C) (NJ nursery) 12.26 0.001

Ornamental plants (exterior landscapes and

interior plantscapes )

– 1 app at 0.42 lb ai/A (C) (OR nursery) 1.89 <0.001

Ornamental plants (exterior landscapes and interior plantscapes)

– 1 app at 0.42 lb ai/A (C) (TN nursery) 8.95 0.001

Trees (including non

- bearing fruit and nut trees), shrubs, evergreens, foliage plants, groundcovers, vines, interior plantscape plants

– 1 app at 0.42 lb ai/A (C) 0.23 <0.001

Trees (including non

- bearing fruit and nut trees), shrubs, evergreens, bedding plants, flowering plants, flowers, foliage plants, groundcovers, vines, interior plantscape plants, vegetable transplants (fruiting, leafy, tuberous, corm)

– 1 app at 0.42 lb ai/A (G) 1.74 <0.001

Turf, golf courses, residential lawns, commercial grounds, parks, playgrounds, athletic fields, sod

farms

– 2 apps at 0.13 lb ai/A (30 days) (G) 1.35 <0.001

Turf, golf courses, residential lawns, commercial grounds, parks, playgrounds, athletic fields, sod

farms

– 2 apps at 0.13 lb ai/A (30 days) (G) (CA turf) 1.43 <0.001

Grassy, weedy, mulched, or bare soil areas in

and around greenhouses, nurseries, interior plantscapes, lath and shade houses, under trees and shrubs that are being grown in

- ground

– 1 app at 0.233 lb ai/A and 1 app at 0.187 lb ai/A (30 days) (G) (FL turf) 2.15 <0.001

Grassy, weedy, mulched, or bare soil areas in and around greenhouses, nurseries, interior plantscapes, lath and shade houses, under trees and shrubs that are being grown in

- ground

– 1 app at 0.233 lb ai/A and 1 app at 0.187 lb ai/A (30 days) (G) (CA turf) 2.41 <0.001

Fly control bait

– 5 apps at 0 .087 lb ai/A ( 7 days) (E) 23.16 0.002

Public health insect control

– 1 app at 0.42 lb 22.52 0.002

### 94 Uses /Application Rate 60

- day

EEC (μg/L) Freshwater

Fish Chronic RQ *

ai/A (E)

Potted ornamentals

– 1 app at 0.5 lb ai/A (C) (CA nursery) 1.49 <0.001

Potted ornamentals

– 1 app at 0.5 lb ai/A (C) (FL nursery) 7.28 0.001

Potted ornamentals

– 1 app at 0.5 lb ai/A (C) (MI nursery) 15.51 0.001

Potted ornamentals

– 1 app at 0.5 lb ai/A (C) (NJ nursery) 14.60 0.001

Potted ornamentals

– 1 app at 0.5 lb ai/A (C) (OR nursery) 2.24 <0.001

Potted ornamentals

– 1 app at 0.5 lb ai/A (C) (TN nursery) 10.65 0.001

Potted ornamentals

– 2 apps at 0.13 lb ai/A (C) (CA nursery) 0.40 <0.001

Potted ornamentals

– 2 apps at 0.13 lb ai/A (C) (FL nursery) 3.50 <0.001

Potted ornamentals

– 2 apps at 0.13 lb ai/A (C) (MI nursery) 7.55 0.001

Potted ornamentals

– 2 apps at 0.13 lb ai/A (C) (NJ nursery) 5.82 0.001

Potted ornamentals

– 2 apps at 0.13 lb ai/A (C) (OR nursery) 1.47 <0.001

Potted ornamentals

– 2 apps at 0.13 lb ai/A (C) (TN nursery) 6.75 0.001

C hronic RQ = use

- specific 60

- day EEC / 10700 μg ai/L (rainbow trout) A = foliar aerial application G = foliar ground application C = chemigation

S = seed treatment

E = Tier 1 GENEEC Model was used



### Cyantraniliprole ranged in toxicity from slightly to very highly toxic to freshwater

in vertebrates on an acute exposure basis

. Risk quotients for acute exposures to freshwater invertebrates ranged from 0.011 to 1.9 ( Table 36 ) . Most uses exceeded the

acute risk to listed species LOC of 0.05 and 55% of those exceeded the acute risk to non

li sted species LOC of 0.5 . Those proposed uses that did not exceed the acute risk LOC s

were: fruiting vegetables chemigation at 0.4 lb ai/A (CA tomato scenario); sunflower seed treatment; trees (including non

- bearing fruit and nut trees), shrubs, evergreen s, foliage plants, groundcovers, vines, interior plantscape plants chemigation at 0.42 lb ai/A; and potted ornamentals chemigation at 2 apps at 0.13 lb ai/A (CA nursery scenario). Therefore, based on the screening

- level assessment , acute risks (direct) ma y result for

many of the proposed uses of cyantraniliprole

.

Risk quotients for chronic exposures to freshwater invertebrates ranged from 0. 035 to 5.8 ( Table 36 ). Sixty

- eight percent of the scenarios exceeded the listed and non

- listed species chronic risk LOC of 1. Thus

, chronic risks (direct) are possible from many of the proposed uses.

### 95 Cyantraniliprole is moderately to highly toxic to estuarine /marine invertebrates on an acute exposure basis. Acute risk quotients for estuarine/marine invertebrates ranged from

< 0.001 to 0.073 ( Table 3 6 ) . The following eight scenarios exceeded the acute risk to listed species LOC of 0.05: cotton aerial and ground spray at 3 apps at 0.133 lb ai/A (MS

and NC cotton sc enarios); cucurbits aerial and ground spray at 2 ap ps at 0.175 lb ai/A and 1 app at 0.05 lb ai/A; fruiting vegetables aerial spray at 2 apps at 0.175 lb ai/A and 1 app at 0.05 lb ai/A (PA tomato scenario); and rapeseed including canola varieties, mustard seed treatment (ND wheat scenario). Chronic risk qu otients ranged from 0.001 to 0.23 (oyster) and < 0.001 to 0.12 (mysid shrimp) . No scenarios exceeded the listed and non

listed species chronic risk LOC of 1. Thus, while mortality (direct) of estuarine/marine

invertebrates is possible following acute exp osure for eight of the proposed uses

, the likelihood of (direct) adverse effects from chronic exposure is considered low

.

Table 36 . RQs for Freshwater and Estuarine/Marine Invertebrates (Based on Surface Water EECs)

Uses /Application Rate Peak

EEC (μg/L) 21

- day

EEC (μg/L) Freshwater

Invertebrate Acute RQ + Freshwater

Invertebrate

Chronic

RQ + Estuarine/

Marine

Invertebrate Acute RQ + Estuarine/

Marine

Invertebrate

Chronic RQ +

Oyster Shrimp

Brassic a vegetable

- 1 app at 0.4 lb ai/A (C) 22.5 22.45 1.1** 3.4*** 0.043 0.13 0.058

Brassica leafy vegetable

– 2 apps at 0.175 lb ai/A and 1 app at 0.05 lb ai/A (7 days) (A) 21.01 20.89 1.0** 3.2*** 0.040 0.13 0.054

Brassica leafy vegetable

– 2 apps at 0.175 lb ai/A and 1 app at 0.05 lb ai/A (7 days) (G) 17.03 16.94 0.83** 2.6*** 0.033 0.10 0.044

Brassica leafy vegetables

– 3 apps at 0.133 lb ai/A (5 days) (A) 16.90 16.81 0.83** 2.6*** 0.033 0.10 0.044

Brassica leafy vegetables

– 3 apps at 0.133 lb ai/A (5 days) (G) 12.83 12.77 0.63** 1.9*** 0.025 0.076 0.033

Bushberries

– 3 apps at 0.133 lb ai/A (5 days) (A) 13.28 13.24 0.65** 2.0*** 0.026 0.079 0.034

Bushberries

– 3 apps at 0.133 lb ai/A (5 days) (G) 8.71 8.69 0.43* 1.3*** 0.017 0.052 0.023

Citrus

– 3 apps at 0.133 lb ai/A (7 days) (A) 16.66 15.58 0.82** 2.4*** 0.032 0.093 0.040

Citrus

– 3 apps at 0.133 lb ai/A (7 days) (G) 14.64 13.58 0.72** 2.1*** 0.028 0.081 0.035

Citrus

– 1 app at 0.4 lb ai/A (C) 11.01 10.13 0.54** 1.5*** 0.021 0.061 0.026

Cotton

– 3 apps at 0.133 lb ai/A (7 days) (A) (CA cotton) 9.21 9.16 0.45* 1.4*** 0.018 0.055 0.024

### 96 Uses /Application Rate Peak

EEC (μg/L) 21

- day

EEC (μg/L) Freshwater

Invertebrate Acute RQ + Freshwater

Invertebrate

Chronic

RQ + Estuarine/

Marine

Invertebrate Acute RQ + Estuarine/

Marine

Invertebrate

Chronic RQ +

Oyster Shrimp

Cotton

– 3 apps at 0.133 lb ai/A (7 days) (G) (CA cotton) 6.11 6.09 0.30* 0.93 0.012 0.036 0.016

Cotton

– 3 apps at 0.133 lb ai/A (7 days) (A) (MS cotton) 29.45 29.07 1.4** 4.4*** 0.057* 0.17 0.075

Cotton

– 3 apps at 0.133 lb ai/A (7 days) (G) (MS cotton) 27.33 29.96 1.3** 4.6*** 0.053* 0.18 0.078

Cotton

– 3 apps at 0.133 lb ai/A (7 days) (A) (NC cotton) 37.97 37.78 1.9** 5.8*** 0.073* 0.23 0.098

Cotton

– 3 apps at 0.133 lb ai/A (7 days) (G) (NC cotton) 35.58 35.40 1.7** 5.4*** 0.068* 0.21 0.092

Cucurbits

– 2 apps at 0.175 lb ai/A and 1 app at 0.05 lb ai/A (5 days) (A) 33.01 32.66 1.6** 5.0*** 0.063* 0.20 0.085

Cucurbits

– 2 apps at

0.175 lb ai/A and 1 app at 0.05 lb ai/A (5 days) (G) 31.79 31.38 1.6** 4.8*** 0.061* 0.19 0.081

Cucurbits

– 2 apps at 0.13 lb ai/A (10 days) (C) 5.33 5.14 0.26* 0.78 0.010 0.031 0.013

Cucurbits

– 1 app at 0.4 lb ai/A (C) 9.66 9.56 0.47* 1.5*** 0.019 0.057 0.025

Fruiting vegetables

– 2 apps at 0.175 lb ai/A and 1 app at 0.05 lb ai/A (5 days) (A) (FL peppers) 15.89 15.74 0.78** 2.4*** 0.031 0.094 0.041

Fruiting vegetables

– 2 apps at 0.175 lb ai/A and 1 app at 0.05 lb ai/A (5 days) (G) (FL peppers) 14.22 14.09 0.70** 2.1*** 0.027 0.084 0.037

Fruiting vegetables

– 2 apps at 0.175 lb ai/A and 1 app at 0.05 lb ai/A (5 days) (A) (CA tomato) 15.91 15.70 0.78** 2.4*** 0.031 0.094 0.041

Fruiting vegetables

– 2 apps at 0.175 lb ai/A and 1 app at 0.05 lb ai/A (5 days) (G) (CA tomato) 13.20 12.86 0.65** 2.0*** 0.025 0.077 0.033

Fruiting vegetables

– 2 apps at 0.175 lb ai/A and 1 app at 0.05 lb ai/A (5 days) (A) (FL tomato) 25.73 25.37 1.3 ** 3.9*** 0.049 0.15 0.066

Fruiting vegetables

– 2 apps at 0.175 lb ai/A and 1 app at 0.05 lb ai/A (5 days) (G) (FL tomato) 24.08 23.74 1.2** 3.6*** 0.046 0.14 0.062

### 97 Uses /Application Rate Peak

EEC (μg/L) 21

- day

EEC (μg/L) Freshwater

Invertebrate Acute RQ + Freshwater

Invertebrate

Chronic

RQ + Estuarine/

Marine

Invertebrate Acute RQ + Estuarine/

Marine

Invertebrate

Chronic RQ +

Oyster Shrimp

Fruiting vegetables

– 2 apps at 0.175 lb ai/A and 1 app at 0.05 lb ai/A (5 days) (A) (PA tomato) 28.14 28.07 1.4** 4.3*** 0.054* 0.17 0.073

Fruiting vegetables

– 2

apps at 0.175 lb ai/A and 1 app at 0.05 lb ai/A (5 days) (G) (PA tomato) 24.87 24.81 1.2** 3.8*** 0.048 0.15 0.064

Fruiting vegetables

– 2 apps at 0.13 lb ai/A (5 days) (C) (FL peppers) 5.03 4.98 0.25* 0.76 0.010 0.030 0.013

Fruiting vegetables

– 2

apps at 0.13 lb ai/A (5 days) (C) (CA tomato) 1.47 1.46 0.072* 0.22 0.003 0.009 0.004

Fruiting vegetables

– 2 apps at 0.13 lb ai/A (5 days) (C) (FL tomato) 10.17 10.04 0.50** 1.5*** 0.020 0.060 0.026

Fruiting vegetables

– 2 apps at 0.13 lb ai/A (5 days) (C) (PA tomato) 12.51 12.48 0.61** 1.9*** 0.024 0.075 0.032

Fruiting vegetables

– 1 app at 0.4 lb ai/A (C) (FL peppers) 25.64 25.42 1.3** 3.9*** 0.049 0.15 0.066

Fruiting vegetables

– 1 app at 0.4 lb ai/A (C) (CA tomato) 0.28 0.27 0.013 0.041 0.001 0.002 <0.001

Fruiting vegetables

– 1 app at 0.4 lb ai/A (C) (FL tomato) 16.79 16.54 0.82** 2.5*** 0.032 0.099 0.043

Fruiting vegetables

– 1 app at 0.4 lb ai/A (C) (PA tomato) 10.97 10.93 0.54** 1.7*** 0.021 0.065 0.028

Leafy vegetables

– 1 app at 0.4 lb ai/A (C) 16.04 15.95 0.79** 2.4*** 0.031 0.096 0.041

Leafy vegetables

– 2 apps at 0.175 lb ai/A and 1 app at 0.05 lb ai/A (7 days) (A) 14.09 14.02 0.69** 2.1*** 0.027 0.084 0.036

Leafy vegetables

– 2 apps at 0.175 lb ai/A and 1 app at 0.05 lb ai/A (7 days) (G) 10.37 10.32 0.51** 1.6*** 0.020 0.062 0.027

Leafy vegetables (except brassica)

– 3 apps at 0.133 lb ai/A (5 days) (A) 10.90 10.83 0.53** 1.7*** 0.021 0.065 0.028

Leafy vegetables (except brassica)

– 3 apps at 0.133 lb ai/A (5 days) (G) 6.81 6.78 0.33* 1.0*** 0.013 0.041 0.018

### 98 Uses /Application Rate Peak

EEC (μg/L) 21

- day

EEC (μg/L) Freshwater

Invertebrate Acute RQ + Freshwater

Invertebrate

Chronic

RQ + Estuarine/

Marine

Invertebrate Acute RQ + Estuarine/

Marine

Invertebrate

Chronic RQ +

Oyster Shrimp

Oil seeds

– 3 apps at 0.133 lb ai/A (7 days) (A) (ND canola) 22.41 22.25 1.1** 3.4*** 0.043 0.13 0.058

Oil seeds

– 3 apps at 0.133 lb ai/A (7 days) (G) (ND canola) 18.31 18.18 0.90** 2.8*** 0.035 0.11 0.047

Oil seeds

– 3 apps at 0.133 lb ai/A (7 days) (A) (ND wheat) 25.47 25.35 1.2** 3.9*** 0.049 0.15 0.066

Oil seeds

– 3 apps at 0.133 lb ai/A (7 days) (G) (ND wheat) 21.54 21.49 1.1** 3.3*** 0.041 0.13 0.056

Pome fruit

– 3 apps at 0.133 lb ai/A (7 days) (A) (CA fruit) 4.98 4.96 0.24* 0.76 0.010 0.030 0.013

Pome fruit

– 3 apps at 0.133 lb ai/A (7 days) (G) (CA fruit) 1.63 1.63 0.08* 0.25 0.003 0.010 0.004

Pome fruit

– 3 apps at 0.133 lb ai/A (7 days) (A) (NC apple) 19.78 19.69 0.97** 3.0*** 0.038 0.12 0.051

Pome fruit

– 3 apps at 0.133 lb ai/A (7 days) (G) (NC apple) 16.27 16.20 0.80** 2.5*** 0.031 0.097 0.042

Pome fruit

– 3 apps at 0.133 lb ai/A (7 days) (A) (OR apple) 12.78 12.73 0.63** 1.9*** 0.025 0.076 0.033

Pome fruit

– 3 apps at 0.133 lb ai/A (7 days) (G) (OR apple) 8.45 8.43 0.41* 1.3*** 0.016 0.051 0.022

Pome fruit

– 3 apps at 0.133 lb ai/A (7 days) (A) (PA apple) 14.53 14.36 0.71** 2.2*** 0.028 0.086 0.037

Pome fruit

– 3 apps at 0.133 lb ai/A (7 days) (G) (PA apple) 11.01 10.91 0.54** 1.7*** 0.021 0.065 0.028

Potatoes

– 1 app at 0.69 lb ai/A (S) (ID potato) 6.53 6.51 0.32* 0.99 0.013 0.039 0.017

Potatoes

– 1 app at 0.69 lb ai/A (S) (ME potato) 8.96 8.90 0.44* 1.4*** 0.017 0.053 0.023

Potatoes

– 1 app at 0.176 lb ai/A (S) (ID potato) 1.67 1.66 0.082* 0.25 0.003 0.010 0.004

Potatoes

– 1 app at 0.176 lb ai/A (S) (ME potato) 2.29 2.27 0.11* 0.35 0.004 0.014 0.006

Corm and tuberous vegetables

– 3 apps at 0.133 lb ai/A (5 days) (A) (ID potato) 19.26 19.14 0.94** 2.9*** 0.037 0.11 0.050

### 99 Uses /Application Rate Peak

EEC (μg/L) 21

- day

EEC (μg/L) Freshwater

Invertebrate Acute RQ + Freshwater

Invertebrate

Chronic

RQ + Estuarine/

Marine

Invertebrate Acute RQ + Estuarine/

Marine

Invertebrate

Chronic RQ +

Oyster Shrimp

Corm and tuberous vegetables

– 3 apps at 0.133 lb ai/A (5 days) (G) (ID potato) 14.52 14.43 0.71** 2.2*** 0.028 0.086 0.037

Corm and tuberous vegetables

– 3 apps at 0.133 lb ai/A (5 days) (A) (ME potato) 25.49 25.43 1.2** 3.9*** 0.049 0.15 0.066

Corm and tuberous vegetables

– 3 apps at 0.133 lb ai/A (5 days) (G) (ME potato) 20.54 20.49 1.0** 3.1*** 0.040 0.12 0.053

Corm and tuberous vegetables

- 1 app at 0.25 lb ai/A (C) (ID potato) 6.90 6.88 0.34* 1.0*** 0.013 0.041 0.018

Corm and tuberous vegetables

- 1 app at 0.25 lb ai/A (C) (ME potato) 10.67 10.65 0.52** 1.6*** 0.021 0.064 0.028

Rapeseed including canola varieties, mustard seed

– 1 app at 0.4 lb ai/A (S) (ND canola) 19.82 19.72 0.97** 3.0*** 0.038 0.12 0.051

Rapeseed including canola varieties, mustard seed

– 1 app at 0.4 lb ai/A (S) (ND wheat) 36.53 36.44 1.8** 5.6*** 0.070* 0.22 0.094

Stone fruit

– 3 apps at 0.133 lb ai/A (7 days) (A) (MI cherry) 19.10 18.98 0.94** 2.9*** 0.037 0.11 0.049

Stone fruit

– 3 apps at 0.133 lb ai/A (7 days) (G) (MI cherry) 14.33 14.23 0.70** 2.2*** 0.028 0.085 0.037

Stone fruit

– 3 apps at 0.133 lb ai/A (7 days) (A) (GA peaches) 6.11 6.03 0.30* 0.92 0.012 0.036 0.016

Stone fruit

– 3 apps at 0.133 lb ai/A (7 days) (G) (GA peaches) 3.33 3.31 0.16* 0.50 0.006 0.020 0.009

Stone fruit

– 3 apps at 0.133 lb ai/A (7 days) (A) (CA fruit) 6.40 6.01 0.31* 0.92 0.012 0.036 0.016

Stone fruit

– 3 apps at 0.133 lb ai/A (7 days) (G) (CA fruit) 3.40 3.11 0.17* 0.47 0.007 0.019 0.008

Sunflower

– 1 app at 0.016 lb ai/A (S) (ND canola) 0.45 0.45 0.022 0.069 0.001 0.003 0.001

Sunflower

– 1 app at 0.016 lb ai/A (S) (ND 0.84 0.84 0.041 0.13 0.002 0.005 0.002

### 100 Uses /Application Rate Peak

EEC (μg/L) 21

- day

EEC (μg/L) Freshwater

Invertebrate Acute RQ + Freshwater

Invertebrate

Chronic

RQ + Estuarine/

Marine

Invertebrate Acute RQ + Estuarine/

Marine

Invertebrate

Chronic RQ +

Oyster Shrimp

wheat)

Tree nuts

– 3 apps at 0.133 lb ai/A (A) (CA almonds) 11.02 10.97 0.54** 1.7*** 0.021 0.066 0.028

Tree nuts

– 3 apps at

0.133 lb ai/A (G) (CA almonds) 8.48 8.44 0.42* 1.3*** 0.016 0.051 0.022

Tree nuts

– 3 apps at 0.133 lb ai/A (A) (GA pecans) 19.27 19.18 0.94** 2.9*** 0.037 0.11 0.050

Tree nuts

– 3 apps at 0.133 lb ai/A (G) (GA pecans) 17.18 17.10 0.84** 2.6*** 0.033 0.10 0.044

Bulb vegetables

– 3 apps at 0.133 lb ai/A (5 days) (A) (CA onion) 6.07 5.96 0.30* 0.91 0.012 0.036 0.015

Bulb vegetables

– 3 apps at 0.133 lb ai/A (5 days) (G) (CA onion) 3.17 3.12 0.16* 0.48 0.006 0.019 0.008

Bulb vegetables

– 3 apps

at 0.133 lb ai/A (5 days) (A) (GA onion) 20.84 20.59 1.0** 3.1*** 0.040 0.12 0.053

Bulb vegetables

– 3 apps at 0.133 lb ai/A (5 days) (G) (GA onion) 18.40 18.21 0.90** 2.8*** 0.035 0.11 0.047

Flowerbeds and ground

covers

– 2 apps at 0.208 lb ai/A (7 days) (G) (CA nursery) 5.45 5.41 0.27* 0.82 0.010 0.032 0.014

Flowerbeds and ground

covers

– 2 apps at 0.208 lb ai/A (7 days) (G) (FL nursery) 16.09 15.96 0.79** 2.4*** 0.031 0.096 0.041

Flowerbeds and ground

covers

– 2 apps at 0.208 lb ai/A (7 days) (G) (MI nursery) 16.27 16.20 0.80** 2.5*** 0.031 0.097 0.042

Flowerbeds and ground

covers

– 2 apps at 0.208 lb ai/A (7 days) (G) (NJ nursery) 14.09 14.03 0.69** 2.1*** 0.027 0.084 0.036

Flowerbeds and ground

covers

– 2 apps at 0.208 lb ai/A (7 days) (G) (OR nursery) 4.25 4.22 0.21* 0.64 0.008 0.025 0.011

Flowerbeds and ground

covers

– 2 apps at 0.208 lb ai/A (7 days) (G) (TN 12.20 12.11 0.60** 1.8*** 0.023 0.073 0.031

### 101 Uses /Application Rate Peak

EEC (μg/L) 21

- day

EEC (μg/L) Freshwater

Invertebrate Acute RQ + Freshwater

Invertebrate

Chronic

RQ + Estuarine/

Marine

Invertebrate Acute RQ + Estuarine/

Marine

Invertebrate

Chronic RQ +

Oyster Shrimp

nursery)

Ornamentals treated by

commercial and consumer applicators

– 2 apps at 0.13 lb ai/A (7 days) (G) (CA nursery) 3.40 3.37 0.17* 0.51 0.007 0.020 0.009

Ornamentals treated by

commercial and consumer applicators

– 2 apps at 0.13 lb ai/A (7 days) (G) (FL nursery) 10.04 9.95 0.49* 1.5*** 0.019 0.060 0.12

Ornamentals treated by

commercial and consumer applicators

– 2 apps at 0.13 lb ai/A (7 days) (G) (MI nursery) 10.15 10.11 0.50** 1.5*** 0.020 0.061 0.026

Ornamentals treated by

commercial and consumer applicators

– 2 apps at 0.13 lb ai/A (7 days) (G) (NJ nursery) 8.79 8.75 0.43* 1.3*** 0.017 0.052 0.023

Ornamentals treated by

commercial and consumer applicators

– 2 apps at 0.13 lb ai/A (7 days) (G) (OR nursery) 2.65 2.64 0.13* 0.40 0.005 0.016 0.007

Ornamentals treated by

commercial and consumer applicators

– 2 apps at 0.13 lb ai/A (7 days) (G) (TN nursery) 7.61 7.56 0.37* 1.2*** 0.015 0.045 0.020

Ornamental plants, fruit and nut trees (non

bearing) and forest seedlings grown in greenhouses, lath and shade houses, containers,

field nurseries and interiorscapes

– 2 apps at 0.13 lb ai/A (14 days) (G) (CA nursery) 3.45 3.42 0.17* 0.52 0.007 0.020 0.009

Ornamental plants, fruit and nut trees (non

bearing) and forest seedlings grown in greenhouses, lath and shade houses, containers,

field nurseries and interiorscapes

– 2 apps at 6.79 6.73 0.33* 1.0*** 0.013 0.040 0.017

### 102 Uses /Application Rate Peak

EEC (μg/L) 21

- day

EEC (μg/L) Freshwater

Invertebrate Acute RQ + Freshwater

Invertebrate

Chronic

RQ + Estuarine/

Marine

Invertebrate Acute RQ + Estuarine/

Marine

Invertebrate

Chronic RQ +

Oyster Shrimp

0.13 lb ai/A (14 days) (G) (FL nursery) Ornamental plants, fruit and nut trees (non

bearing) and forest seedlings grown in greenhouses, lath and shade houses, containers,

field nurseries and interiorscapes

– 2 apps at

0.13 lb ai/A (14 days) (G) (MI nursery) 10.24 10.19 0.50** 1.6*** 0.020 0.061 0.026

Ornamental plants, fruit and nut trees (non

bearing) and forest seedlings grown in greenhouses, lath and shade houses, containers,

field nurseries and interiorscapes

– 2 apps at

0.13 lb ai/A (14 days) (G) (NJ nursery) 9.07 9.03 0.44* 1.4*** 0.017 0.054 0.023

Ornamental plants, fruit and nut trees (non

bearing) and forest seedlings grown in greenhouses, lath and shade houses, containers,

field nurseries and interiorscapes

– 2 apps at 0.13 lb ai/A (14 days) (G) (OR nursery) 2.72 2.71 0.13* 0.41 0.005 0.016 0.007

Ornamental plants, fruit and nut trees (non

bearing) and forest seedlings grown in greenhouses, lath and shade houses, containers,

field nurseries and interiorscapes

– 2 apps at 0.13 lb ai/A (14 days) (TN nursery) 7.62 7.57 0.37* 1.2*** 0.015 0.045 0.020

Ornamental plants, fruit and nut trees (non

bearing) and forest seedlings grown in greenhouses, lath and shade houses, containers,

field nurseries and 0.41 0.40 0.020 0.061 0.001 0.002 0.001

### 103 Uses /Application Rate Peak

EEC (μg/L) 21

- day

EEC (μg/L) Freshwater

Invertebrate Acute RQ + Freshwater

Invertebrate

Chronic

RQ + Estuarine/

Marine

Invertebrate Acute RQ + Estuarine/

Marine

Invertebrate

Chronic RQ +

Oyster Shrimp

interiorscapes

– 2 apps at 0.13 lb ai/A (14 days) (C) (CA nursery) Ornamental plants, fruit and nut trees (non

bearing) and forest seedlings grown in greenhouses, lath and shade houses, containers,

field nurseries and interiorscapes

– 2 apps at 0.13 lb ai/A (14 days) (C) (FL nursery) 3.65 3.60 0.18* 0.55 0.007 0.022 0.009

Ornamental plants, fruit and nut trees (non

bearing) and forest seedlings grown in greenhouses, lath and shade houses, containers,

field nurseries and interiorscapes

– 2 apps at 0.13 lb ai/A (14 days) (C) (MI nursery) 7.69 7.66 0.38* 1.2*** 0.015 0.046 0.020

Ornamental plants, fruit and nut trees (non

bearing) and forest seedlings grown in greenhouses, lath and shade houses, containers,

field nurseries and interiorscapes

– 2 apps at 0.13 lb ai/A (14 days) (C) (NJ nursery) 5.92 5.87 0.29* 0.89 0.011 0.035 0.015

Ornamental plants, fruit and nut trees (non

bearing) and forest seedlings grown in greenhouses, lath and shade houses, containers,

field nurseries and interiorscapes

– 2 apps at 0.13 lb ai/A (14 days) (C) (OR nursery) 1.49 1.49 0.073* 0.23 0.003 0.009 0.004

Ornamental plants, fruit and nut trees (non

bearing) and forest seedlings grown in greenhouses, lath and shade houses, containers, 6.94 6.88 0.34* 1.0*** 0.013 0.041 0.12

### 104 Uses /Application Rate Peak

EEC (μg/L) 21

- day

EEC (μg/L) Freshwater

Invertebrate Acute RQ + Freshwater

Invertebrate

Chronic

RQ + Estuarine/

Marine

Invertebrate Acute RQ + Estuarine/

Marine

Invertebrate

Chronic RQ +

Oyster Shrimp

field nurseries and interiorscapes

– 2 apps at 0.13 lb ai/A (14 days) (C) (TN nursery) Ornamental plants (exterior landscapes and interior plantscapes)

– 1 app at 0.42 lb ai/A (G) (CA nursery) 5.94 5.91 0.29* 0.90 0.011 0.035 0.015

Ornamental plants (exterior landscapes and interior plantscapes )

– 1 app at 0.42 lb ai/A (G) (FL nursery) 10.20 10.12 0.50** 1.5*** 0.020 0.061 0.026

Ornamental plants (exterior landscapes and interior plantscapes)

– 1 app at 0.42 lb ai/A (G) (MI nursery) 16.26 16.17 0.80** 2.5*** 0.031 0.097 0.042

Ornamental plants (exterior landscapes and interior plantscapes )

– 1 app at 0.42 lb ai/A (G) (NJ nursery) 18.54 18.47 0.91** 2.8*** 0.036 0.11 0.048

Ornamental plants (exterior landscapes and interior plantscapes )

– 1 app at 0.42 lb ai/A (G) (OR nursery) 4.21 4.19 0.21* 0.64 0.008 0.025 0.011

Ornamental plants (exterior landscapes and interior plantscapes)

– 1 app at 0.42 lb ai/A (G) (TN nursery) 10.60 10.55 0.52** 1.6*** 0.020 0.063 0.027

Ornamental plants (exterior landscapes and interior plantscapes)

– 1 app at 0.42 lb ai/A (C) (CA nursery) 1.28 1.27 0.063* 0.19 0.002 0.008 0.003

Ornamental plants (exterior landscapes and interior plantscapes )

– 1 app at 0.42 lb ai/A (C) (FL nursery) 6.31 6.25 0.31* 0.95 0.012 0.037 0.016

Ornamental plants (exterior landscapes and interior plantscapes)

– 1 app at 0.42 lb ai/A (C) (MI nursery) 13.19 13.15 0.65** 2.0*** 0.025 0.079 0.034

### 105 Uses /Application Rate Peak

EEC (μg/L) 21

- day

EEC (μg/L) Freshwater

Invertebrate Acute RQ + Freshwater

Invertebrate

Chronic

RQ + Estuarine/

Marine

Invertebrate Acute RQ + Estuarine/

Marine

Invertebrate

Chronic RQ +

Oyster Shrimp

Ornamental plants (exterior landscapes and interior plantscapes )

– 1 app at 0.42 lb ai/A (C) (NJ nursery) 12.50 12.43 0.61** 1.9*** 0.024 0.074 0.032

Ornamental plants (exterior landscapes and interior plantscapes )

– 1 app at 0.42 lb ai/A (C) (OR nursery) 1.90 1.90 0.093* 0.29 0.004 0.011 0.005

Ornamental plants (exterior landscapes and interior plantscapes)

– 1 app at 0.42 lb ai/A (C) (TN nursery) 9.14 9.09 0.45* 1.4*** 0.018 0.054 0.024

Trees (including non

bearing fruit and nut trees), shrubs, evergreens, foliage plants, groundcovers, vines,

interior plantscape plants

– 1 app at 0.42 lb ai/A (C) 0.23 0.23 0.011 0.035 <0.001 0.001 0.001

Trees (including non

bearing fruit and nut trees), shrubs, evergreens, bedding plants, flowering plants, flowers, foliage plants, groundcovers, vines, interior plantscape plants, vegetable transplants (fruiting, leafy, tuberous, corm)

– 1 app at 0.42 lb ai/A (G) 1.77 1.76 0.087* 0.27 0.003 0.011 0.005

Turf, golf courses, residential lawns, commercial grounds, parks, playgrounds, athletic fields, sod farms

– 2 apps at 0.13 lb ai/A (30 days) (G) (FL turf) 1.39 1.37 0.068* 0.21 0.003 0.008 0.003

Turf, golf courses, residential lawns, commercial grounds, parks, playgrounds, athletic fields, sod farms

– 2 apps at 0.13 lb ai/A (30 days) (G) (CA turf) 1.46 1.45 0.072* 0.22 0.003 0.009 0.004

Grassy, weedy, mulched,

or bare soil areas in and 2.21 2.19 0.11* 0.33 0.004 0.013 0.006

### 106 Uses /Application Rate Peak

EEC (μg/L) 21

- day

EEC (μg/L) Freshwater

Invertebrate Acute RQ + Freshwater

Invertebrate

Chronic

RQ + Estuarine/

Marine

Invertebrate Acute RQ + Estuarine/

Marine

Invertebrate

Chronic RQ +

Oyster Shrimp

around greenhouses, nurseries, interior plantscapes, lath and shade houses, under trees and shrubs that are being grown in

- ground

– 1 app at 0.233 lb ai/A and 1 app

at 0.187 lb ai/A (30 days) (G) (FL turf) Grassy, weedy, mulched,

or bare soil areas in and around greenhouses, nurseries, interior plantscapes, lath and shade houses, under trees and shrubs that are being grown in

- ground

– 1 app at 0.233 lb ai/A and 1 app at 0.187 lb ai/A (30 days) (G) (CA turf) 2.46 2.44 0.12* 0.37 0.005 0.015 0.006

Fly control bait

– 5 apps at 0.087 lb ai/A ( 7 days) (E) 23.67 23.49 1.2** 3.6*** 0.046 0.14 0.061

Public health insect

control

– 1 app at 0.42 lb ai/A (E) 23.02 22.85 1.1** 3.5*** 0.044 0.14 0.059

Potted ornamentals

– 1 app at 0.5 lb ai/A (C) (CA nursery) 1.52 1.51 0.075* 0.23 0.003 0.009 0.004

Potted ornamentals

– 1 app at 0.5 lb ai/A (C) (FL nursery) 7.51 7.44 0.37* 1.1*** 0.014 0.045 0.019

Potted ornamentals

– 1 app at 0.5 lb ai/A (C) (MI nursery) 15.71 15.66 0.77** 2.4*** 0.030 0.094 0.041

Potted ornamentals

– 1 app at 0.5 lb ai/A (C) (NJ nursery) 14.89 14.80 0.73** 2.3*** 0.029 0.089 0.038

Potted ornamentals

– 1 app at 0.5 lb ai/A (C) (OR nursery) 2.27 2.26 0.11* 0.34 0.004 0.014 0.006

Potted ornamentals

– 1 app at 0.5 lb ai/A (C) (TN nursery) 10.88 18.82 0.53** 2.9*** 0.021 0.11 0.049

Potted ornamentals

– 2 apps at 0.13 lb ai/A (C) (CA nursery) 0.41 0.40 0.020 0.061 0.001 0.002 0.001

Potted ornamentals

– 2 apps at 0.13 lb ai/A (C) 3.65 3.60 0.18* 0.55 0.007 0.022 0.009

### 107 Uses /Application Rate Peak

EEC (μg/L) 21

- day

EEC (μg/L) Freshwater

Invertebrate Acute RQ + Freshwater

Invertebrate

Chronic

RQ + Estuarine/

Marine

Invertebrate Acute RQ + Estuarine/

Marine

Invertebrate

Chronic RQ +

Oyster Shrimp

(FL nursery)

Potted ornamentals

– 2 apps at 0.13 lb ai/A (C) (MI nursery) 7.69 7.66 0.38* 1.2*** 0.015 0.046 0.020

Potted ornamentals

– 2 apps at 0.13 lb ai/A (C) (NJ nursery) 5.92 5.87 0.29* 0.89 0.011 0.035 0.015

Potted ornamentals

– 2 apps at 0.13 lb ai/A (C) (OR nursery) 1.49 1.49 0.073* 0.23 0.003 0.009 0.004

Potted ornamentals

– 2 apps at 0.13 lb ai/A (C) (TN nursery) 6.94 6.88 0.34* 1.0*** 0.013 0.041 0.018

+ Acute freshwater invert RQ = use

- specific peak EEC / 20.4 μg ai/L ( water flea ); chronic freshwater invert RQ =

use

- specific 21

- day EEC / 6.56 μg ai/L ( water flea ); acute estuarine/marine invert = use

- specific peak EEC / 520 μg ai/L (Eastern oyster); chronic estuarine/marine invert = use

- specific 21

- day EEC / 167 μg ai/L (ACR eastern oyster)

and use

- specific 21

- day EEC / 386 μg ai/L (ACR mysid shrimp) *Exceeds the acute risk to listed species LOC of 0.05

**Exceeds the acute risk to non

- listed species LOC of 0.5

***Exceeds the chronic risk LOC of 1 A = foliar aerial application G = foliar ground application C = chemigation

S = seed treatment

E = Tier 1 GENEEC Model was used



### Benthic Invertebrates Cyantra niliprole is highly toxic to benthic inverteb rates on an acute exposure basis. Acute risk quotients for benthic invertebrates ranged from <0.001 to 0.051 ( Table 37 )

. Only one use exceeded the acute risk to listed species LOC of 0.05 : rapeseed including canola varieties, mustard seed seed treatment (ND wheat scenario). Thus, benthic

invertebrate mortality from acute exposure to c yantraniliprole may occur from the proposed rapeseed seed treatment use under certain agricultural scenarios.

Chronic risk quotients ranged from 0.022 to 3.7 ( Table 37 )

. Forty

- six percent of the uses

exceeded the listed and non

- listed species chronic risk LOC of 1. Given these results, some of the proposed uses for cyantraniliprole may result in chronic risks to benthic

invertebrates.

Table 37

. RQs for Benthic Invertebrates (Based on Pore W ater EECs)

Uses /Application Rate Peak EEC (μg/L) 21

- day

EEC (μg/L) Benthic

Invertebrate Acute RQ * Benthic

Invertebrate

Chronic

RQ *

Brassica vegetable

- 1 app at 0.4 lb ai/A (C) 20.24 20.14 0.028 2.0***

### 108 Uses /Application Rate Peak EEC (μg/L) 21

- day

EEC (μg/L) Benthic

Invertebrate Acute RQ * Benthic

Invertebrate

Chronic

RQ *
Brassica leafy vegetable

– 2 apps at 0.175 lb ai/A and 1 app at 0.05 lb ai/A (7 days) (A) 19.07 19.07 0.027 1.9***

Brassica leafy vegetable

– 2 apps at 0.175 lb ai/A and 1 app at 0.05 lb ai/A (7 days) (G) 15.42 15.41 0.021 1.5***

Brassica leafy vegetables

– 3 apps at 0.133 lb ai/A (5 days) (A) 15.44 15.44 0.021 1.5***

Brassica leafy vegetables

– 3 apps at 0.133 lb ai/A (5 days) (G) 11.70 11.69 0.016 1.2***

Bushberries

– 3 apps at 0.133 lb ai/A (5 days) (A) 12.90 12.89 0.018 1.3***

Bushberries

– 3 apps at 0.133 lb ai/A (5 days) (G) 8.51 8.50 0.012 0.85

Citrus

– 3 apps at 0.133 lb ai/A (7 days) (A) 13.23 13.23 0.018 1.3***

Citrus

– 3 apps at 0.133 lb ai/A (7 days) (G) 11.46 11.46 0.016 1.1***

Citrus

– 1 app at 0.4 lb ai/A (C) 9.24 9.23 0.013 0.92

Cotton

– 3 apps at 0.133 lb ai/A (7 days) (A) (CA cotton) 8.33 8.33 0.012 0.83

Cotton

– 3 apps at 0.133 lb ai/A (7 days) (G) (CA cotton) 5.45 5.45 0.008 0.55

Cotton

– 3 apps at 0.133 lb ai/A (7 days) (A) (MS cotton) 25.72 25.71 0.036 2.6***

Cotton

– 3 apps at 0.133 lb ai/A (7 days) (G) (MS cotton) 23.79 23.78 0.033 2.4***

Cotton

– 3 apps at 0.133 lb ai/A (7 days) (A) (NC cotton) 34.01 33.76 0.047 3.4***

Cotton

– 3 apps at 0.133 lb ai/A (7 days) (G) (NC cotton) 31.80 31.47 0.044 3.1***

Cucurbits

– 2 apps at 0.175 lb ai/A and 1 app at 0.05 lb ai/A (5 days) (A) 25.54 25.45 0.036 2.5***

Cucurbits

– 2 apps at 0.175 lb ai/A and 1 app at 0.05 lb ai/A (5 days) (G) 24.32 24.23 0.034 2.4***

Cucurbits

– 2 apps at 0.13 lb ai/A (10 days) (C) 3.96 3.96 0.006 0.40

Cucurbits

– 1 app at 0.4 lb ai/A (C) 7.78 7.74 0.011 0.77
Fruiting vegetables

– 2 apps at 0.175 lb ai/A and 1 app at 0.05 lb ai/A (5 days) (A) (FL peppers) 12.96 12.95 0.018 1.3***

Fruiting vegetables

– 2 apps at 0.175 lb ai/A and 1 app at 0.05 lb ai/A (5 days) (G) (FL peppers) 11.17 11.17 0.016 1.1***

Fruiting vegetables

– 2 apps at 0.175 lb ai/A and 1 app at 0.05 lb ai/A (5 days) (A) (CA tomato) 14.41 14.40 0.020 1.4***

Fruiting vegetables

– 2 apps at 0.175 lb ai/A and 1 app at 0.05 lb ai/A (5 days) (G) (CA tomato) 11.75 11.74 0.016 1.2***

Fruiting vegetables

– 2 apps at 0.175 lb ai/A and 1 app at 0.05 lb ai/A (5 days) (A) (FL tomato) 20.31 20.31 0.028 2.0***

Fruiting vegetables

– 2 apps at 0.175 lb ai/A 18.94 18.94 0.026 1.9***

### 109 Uses /Application Rate Peak EEC (μg/L) 21

- day

EEC (μg/L) Benthic

Invertebrate Acute RQ * Benthic

Invertebrate

Chronic

RQ *
and 1 app at 0.05 lb ai/A (5 days) (G) (FL tomato) Fruiting vegetables

– 2 apps at 0.175 lb ai/A and 1 app at 0.05 lb ai/A (5 days) (A) (PA tomato) 26.49 25.87 0.037 2.6***

Fruiting vegetables

– 2 apps at 0.175 lb ai/A and 1 app at 0.05 lb ai/A (5 days) (G) (PA tomato) 23.42 22.79 0.033 2.3***

Fruiting vegetables

– 2 apps at 0.13 lb ai/A (5 days) (C) (FL peppers) 4.01 4.01 0.006 0.40

Fruiting vegetables

– 2 apps at 0.13 lb ai/A (5 days) (C) (CA tomato) 1.29 1.28 0.002 0.13

Fruiting vegetables

– 2 apps at 0.13 lb ai/A (5 days) (C) (FL tomato) 8.65 8.65 0.012 0.87

Fruiting vegetables

– 2 apps at 0.13 lb ai/A (5 days) (C) (PA tomato) 11.05 10.72 0.015 1.1***

Fruiting vegetables

– 1 app at 0.4 lb ai/A (C) (FL peppers) 24.60 23.83 0.034 2.4***

Fruiting vegetables

– 1 app at 0.4 lb ai/A (C) (CA tomato) 0.24 0.24 <0.001 0.024

Fruiting vegetables

– 1 app at 0.4 lb ai/A (C) (FL tomato) 12.51 12.51 0.017 1.3***

Fruiting vegetables

– 1 app at 0.4 lb ai/A (C) (PA tomato) 10.84 10.82 0.015 1.1***

Leafy vegetables

– 1 app at 0.4 lb ai/A (C) 14.03 14.00 0.020 1.4***
Leafy vegetables

– 2 apps at 0.175 lb ai/A and 1 app at 0.05 lb ai/A (7 days) (A) 13.03 13.02 0.018 1.3***

Leafy vegetables

– 2 apps at 0.175 lb ai/A and 1 app at 0.05 lb ai/A (7 days) (G) 9.38 9.37 0.013 0.94

Leafy vegetables (except brassica)

– 3 apps at 0.133 lb ai/A (5 days) (A) 10.25 10.24 0.014 1.0***

Leafy vegetables (except brassica)

– 3 apps at 0.133 lb ai/A (5 days) (G) 6.44 6.43 0.009 0.64

Oil seeds

– 3 apps at 0.133 lb ai/A (7 days) (A) (ND canola) 20.55 20.52 0.029 2.1***

Oil seeds

– 3 apps at 0.133 lb ai/A (7 days) (G) (ND canola) 16.66 16.63 0.023 1.7***

Oil seeds

– 3 apps at 0.133 lb ai/A (7 days) (A) (ND wheat) 24.65 24.58 0.034 2.5***

Oil seeds

– 3 apps at 0.133 lb ai/A (7 days) (G) (ND wheat) 20.67 20.67 0.029 2.1***

Pome fruit

– 3 apps at 0.133 lb ai/A (7 days) (A) (CA fruit) 4.62 4.61 0.006 0.46

Pome fruit

– 3 apps at 0.133 lb ai/A (7 days) (G) (CA fruit) 1.49 1.48 0.002 0.15

Pome fruit

– 3 apps at 0.133 lb ai/A (7 days) (A) (NC apple) 18.14 18.13 0.025 1.8***

Pome fruit

– 3 apps at 0.133 lb ai/A (7 days) (G) (NC apple) 14.80 14.79 0.021 1.5***

Pome fruit

– 3 apps at 0.133 lb ai/A (7 days) 11.91 11.91 0.017 1.2***

### 110 Uses /Application Rate Peak EEC (μg/L) 21

- day

EEC (μg/L) Benthic

Invertebrate Acute RQ * Benthic

Invertebrate

Chronic

RQ *
(A) (OR apple)

Pome fruit

– 3 apps at 0.133 lb ai/A (7 days) (G) (OR apple) 7.77 7.68 0.011 0.77

Pome fruit

– 3 apps at 0.133 lb ai/A (7 days) (A) (PA apple) 12.98 12.98 0.018 1.3***

Pome fruit

– 3 apps at 0.133 lb ai/A (7 days) (G) (PA apple) 9.85 9.85 0.014 0.99

Potatoes

– 1 app at 0.69 lb ai/A (S) (ID potato) 5.80 5.80 0.008 0.58

Potatoes

– 1 app at 0.69 lb ai/A (S) (ME potato) 8.21 8.20 0.011 0.82

Potatoes

– 1 app at 0.176 lb ai/A (S) (ID potato) 1.48 1.48 0.002 0.15

Potatoes

– 1 app at 0.176 lb ai/A (S) (ME potato) 2.10 2.09 0.003 0.21

Corm and tuberous vegetables

– 3 apps at 0.133 lb ai/A (5 days) (A) (ID potato) 18.22 18.22 0.025 1.8***

Corm and tuberous vegetables

– 3 apps at 0.133 lb ai/A (5 days) (G) (ID potato) 13.77 13.77 0.019 1.4***

Corm and tuberous vegetables

– 3 apps at 0.133 lb ai/A (5 days) (A) (ME potato) 25.22 25.20 0.035 2.5***

Corm and tuberous vegetables

– 3 apps at 0.133 lb ai/A (5 days) (G) (ME potato) 20.36 20.33 0.028 2.0***

Corm and tuberous vegetables

- 1 app at 0.25 lb ai/A (C) (ID potato ) 6.58 6.56 0.009 0.66

Corm and tuberous vegetables

- 1 app at 0.25 lb ai/A (C) (ME potato) 10.51 10.50 0.015 1.5***

Rapeseed including canola varieties, mustard

seed

– 1 app at 0.4 lb ai/A (S) (ND canola) 17.98 17.96 0.025 1.8***

Rapeseed including canola varieties, mustard

seed

– 1 app at 0.4 lb ai/A (S) (ND wheat) 36.74 36.63 0.051* 3.7***

Stone fruit

– 3 apps at 0.133 lb ai/A (7 days) (A) (MI cherry) 18.03 18.00 0.025 1.8***

Stone fruit

– 3 apps at 0.133 lb ai/A (7 days) (G) (MI cherry) 13.51 13.50 0.019 1.4***

Stone fruit

– 3 apps at 0.133 lb ai/A (7 days) (A) (GA peaches) 5.41 5.41 0.008 0.54

Stone fruit

– 3 apps at 0.133 lb ai/A (7 days) (G) (GA peaches) 3.32 3.28 0.005 0.33

Stone fruit

– 3 apps at 0.133 lb ai/A (7 days) (A) (CA fruit) 5.65 5.65 0.008 0.57

Stone fruit

– 3 apps at 0.133 lb ai/A (7 days) (G) (CA fruit) 3.03 3.03 0.004 0.30

Sunflower

– 1 app at 0.016 lb ai/A (S) (ND canola) 0.41 0.41 0.001 0.041

Sunflower

– 1 app at 0.016 lb ai/A (S) (ND wheat) 0.85 0.84 0.001 0.084

Tree nuts

– 3 apps at 0.133 lb ai/A (A) (CA almonds) 9.89 9.79 0.014 0.98

Tree nuts

– 3 apps at 0.133 lb ai/A (G) (CA almonds) 7.17 7.06 0.010 0.71

### 111 Uses /Application Rate Peak EEC (μg/L) 21

- day

EEC (μg/L) Benthic

Invertebrate Acute RQ * Benthic

Invertebrate

Chronic

RQ *

Tree nuts

– 3 apps at 0.133 lb ai/A (A) (GA pecans) 17.44 17.20 0.024 1.7***

Tree nuts

– 3 apps at 0.133 lb ai/A (G) (GA pecans) 15.41 15.19 0.021 1.5***

Bulb vegetables

– 3 apps at 0.133 lb ai/A (5 days) (A) (CA onion) 5.10 5.10 0.007 0.51 Bulb vegetables

– 3 apps at 0.133 lb ai/A (5 days) (G) (CA onion) 2.74 2.73 0.004 0.27 Bulb vegetables

– 3 apps at 0.133 lb ai/A (5 days) (A) (GA onion) 19.76 19.69 0.027 2.0*** Bulb vegetables

– 3 apps at 0.133 lb ai/A (5 days) (G) (GA onion) 17.87 17.81 0.025 1.8*** Flowerbeds and ground covers

– 2 apps at 0.208 lb ai/A (7 days) (G) (CA nursery) 5.22 5.22 0.007 0.52 Flowerbeds and ground covers

– 2 apps at 0.208 lb ai/A (7 days) (G) (FL nursery) 16.24 16.09 0.023 1.6*** Flowerbeds and ground covers

– 2 apps at 0.208 lb ai/A (7 days) (G) (MI nursery) 14.62 14.61 0.020 1.5*** Flowerbeds and ground covers

– 2 apps at 0.208 lb ai/A (7 days) (G) (NJ nursery) 12.42 12.42 0.017 1.2*** Flowerbeds and ground covers

– 2 apps at 0.208 lb ai/A (7 days) (G) (OR nursery) 3.91 3.91 0.005 0.39 Flowerbeds and ground covers

– 2 apps at 0.208 lb ai/A (7 days) (G) (TN nursery) 10.85 10.84 0.015 1.1***

Ornamentals treated by commercial and consumer applicators

– 2 apps at 0.13 lb ai/A (7 days) (G) (CA nursery) 3.25 3.25 0.005 0.33 Ornamentals treated by commercial and consumer applicators

– 2 apps at 0.13 lb ai/A (7 days) (G) (FL nursery) 10.13 10.04 0.014 1.0*** Ornamentals treated by commercial and consumer applicators

– 2 apps at 0.13 lb ai/A (7 days) (G) (MI nursery) 9.12 9.11 0.013 0.91 Ornamentals treated by commercial and consumer applicators

– 2 apps at 0.13 lb ai/A (7 days) (G) (NJ nursery) 7.75 7.75 0.011 0.78 Ornamentals treated by commercial and consumer applicators

– 2 apps at 0.13 lb ai/A (7 days) (G) (OR nursery) 2.44 2.44 0.003 0.24 Ornamentals treated by commercial and consumer applicators

– 2 apps at 0.13 lb ai/A (7 days) (G) (TN nursery) 6.77 6.76 0.009 0.68 Ornamental plants, fruit and nut trees (non

bearing) and forest seedlings grown in greenhouses, lath and shade houses, containers, field nurseries and interiorscapes

– 2 apps at 0.13 lb ai/A (14 days) (CA nursery) 3.26 3.26 0.005 0.33 Ornamental plants, fruit and nut trees (non

bearing) and forest seedlings grown in greenhouses, lath and shade houses, containers, field nurseries and interiorscapes

– 2 apps at 5.76 5.76 0.008 0.58

### 112 Uses /Application Rate Peak EEC (μg/L) 21

- day

EEC (μg/L) Benthic

Invertebrate Acute RQ * Benthic

Invertebrate

Chronic

RQ *
0.13 lb ai/A (14 days) (FL nursery)

Ornamental plants, fruit and nut trees (non

bearing) and forest seedlings grown in greenhouses, lath and shade houses, containers, field nurseries and interiorscapes

– 2 apps at 0.13 lb ai/A (14 days) (MI nursery) 9.31 9.31 0.013 0.93 Ornamental plants, fruit and nut trees (non

bearing) and forest seedlings grown in greenhouses, lath and shade houses, containers, field nurseries and interiorscapes

– 2 apps at 0.13 lb ai/A (14 days) (NJ nursery) 8.01 8.01 0.011 0.80 Ornamental plants, fruit and nut trees (non

bearing) and forest seedlings grown in greenhouses, lath and shade houses, containers, field nurseries and interiorscapes

– 2 apps at 0.13 lb ai/A (14 days) (OR nursery) 2.47 2.47 0.003 0.25 Ornamental plants, fruit and nut trees (non

bearing) and forest seedlings gro wn in greenhouses, lath and shade houses, containers, field nurseries and interiorscapes

– 2 apps at 0.13 lb ai/A (14 days) (TN nursery) 6.65 6.65 0.009 0.67 Ornamental plants, fruit and nut trees (non

bearing) and forest seedlings grown in greenhouses, lath and shade houses, containers, field nurseries and interiorscapes

– 2 apps at 0.13 lb ai/A (14 days) (C) (CA nursery) 0.41 0.41 0.001 0.041 Ornamental plants, fruit and nut trees (non

bearing) and forest seedlings grown in greenhouses, lath and shade houses, containers, field nurseries and interiorscapes

– 2 apps at 0.13 lb ai/A (14 days) (C) (FL nursery) 2.92 2.92 0.004 0.29 Ornamental plants, fruit and nut trees (non

bearing) and forest seedlings grown in greenhouses, lath and shade houses, containers, field nurseries and interiorscapes

– 2 apps at 0.13 lb ai/A (14 days) (C) (MI nursery) 6.97 6.97 0.010 0.70 Ornamental plants, fruit and nut trees (non

bearing) and forest seedlings grown in greenhouses, lath and shade houses, containers, field nurseries and interiorscapes

– 2 apps at 0.13 lb ai/A (14 days) (C) (NJ nursery) 5.29 5.29 0.007 0.53 Ornamental plants, fruit and nut trees (non

bearing) and forest seedlings grown in greenhouses, lath and shade houses, containers,

field nurseries and interiorscapes

– 2 apps at 0.13 lb ai/A (14 days) (C) (OR nursery) 1.34 1.34 0.002 0.13 Ornamental plants, fruit and nut trees (non

bearing) and forest seedlings grown in greenhouses, lath and shade houses, containers,

field nurseries and interiorscapes

– 2 apps at 0.13 lb ai/A (14 days) (C) (TN nursery) 5.88 5.86 0.008 0.59

### 113 Uses /Application Rate Peak EEC (μg/L) 21

- day

EEC (μg/L) Benthic

Invertebrate Acute RQ * Benthic

Invertebrate

Chronic

RQ *
Ornamental plants (exterior landscapes and interior plantscapes)

– 1 app at 0.42 lb ai/A (G) (CA nursery) 5.49 5.49 0.008 0.55 Ornamental plants (exterior landscapes and interior plantscapes )

– 1 app at 0.42 lb ai/A (G) (FL nursery) 8.74 8.68 0.012 0.87 Ornamental plants (exterior landscapes and interior plantscapes)

– 1 app at 0.42 lb ai/A (G) (MI nursery) 14.82 14.82 0.021 1.5*** Ornamental plants (exterior landscapes and interior plantscapes )

– 1 app at 0.42 lb ai/A (G) (NJ nursery) 18.03 17.98 0.025 1.8*** Ornamental plants (exterior landscapes and interior plantscapes )

– 1 app at 0.42 lb ai/A (G) (OR nursery) 3.88 3.88 0.005 0.39 Ornamental plants (exterior landscapes and interior plantscapes)

– 1 app at 0.42 lb ai/A (G) (TN nursery) 9.39 9.36 0.013 0.94 Ornamental plants (exterior landscapes and interior plantscapes)

– 1 app at 0.42 lb ai/A (C) (CA nursery) 1.30 1.30 0.002 0.13 Ornamental plants (exterior landscapes and interior plantscapes )

– 1 app at 0.42 lb ai/A (C) (FL nursery) 4.97 4.97 0.007 0.50 Ornamental plants (exterior landscapes and interior plantscapes)

– 1 app at 0.42 lb ai/A (C) (MI nursery) 11.67 11.67 0.016 1.2***

Ornamental plants (exterior landscapes and interior plantscapes )

– 1 app at 0.42 lb ai/A (C) (NJ nursery) 11.59 11.59 0.016 1.2*** Ornamental plants (exterior landscapes and interior plantscapes )

– 1 app at 0.42 lb ai/A (C) (OR nursery) 1.90 1.89 0.003 0.19 Ornamental plants (exterior landscapes and interior plantscapes)

– 1 app at 0.42 lb ai/A (C) (TN nursery) 7.87 7.84 0.011 0.78 Trees (including non

- bearing fruit and nut trees), shrubs, evergreens, foliage plants, groundcovers, vines, interior plantscape plants

– 1 app at 0.42 lb ai/A (C) 0.22 0.22 <0.001 0.022 Trees (including non

- bearing fruit and nut trees), shrubs, evergreens, bedding plants, flowering plants, flowers, foliage plants, groundcovers, vines, interior plantscape plants, vegetable transplants (fruiting, leafy, tuberous, corm)

– 1 app at 0.42 lb ai/A (G) 1.61 1.61 0.002 0.16 Turf, golf courses, residential lawns, commercial grounds, parks, playgrounds, athletic fields, sod farms

– 2 apps at 0.13 lb ai/A (30 days) (G) 1.31 1.30 0.002 0.13

### 114 Uses /Application Rate Peak EEC (μg/L) 21

- day

EEC (μg/L) Benthic

Invertebrate Acute RQ * Benthic

Invertebrate

Chronic

RQ *
Turf, golf courses, residential lawns, commercial grounds, parks, playgrounds, athletic fields, sod farms

– 2 apps at 0.13 lb ai/A (30 days) (G) (CA turf) 1.37 1.37 0.002 0.14

Grassy, weedy, mulched, or bare soil areas in and around greenhouses, nurseries, interior plantscapes, lath and shade houses , under trees and shrubs that are being grown in

- ground

– 1 app at 0.233 lb ai/A and 1 app at 0.187 lb ai/A (30 days) (G) (FL turf) 1.98 1.97 0.003 0.20

Grassy, weedy, mulched, or bare soil areas in and around greenhouses, nurseries, interior plantscapes, lath and shade houses , under trees and shrubs that are being grown in

- ground

– 1 app at 0.233 lb ai/A and 1 app at 0.187 lb ai/A (30 days) (G) (CA turf) 2.27 2.27 0.003 0.23

Fly control bait

– 5 apps at 0.087 lb ai/A ( 7 days) (E) 23.67 23.49 0.033 2.3***

Public health insect control

– 1 app at 0.42 lb ai/A (E) 23.02 22.85 0.032 2.3***

Potted ornamentals

– 1 app at 0.5 lb ai/A (C) (CA nursery) 1.55 1.54 0.002 0.15

Potted ornamentals

– 1 app at 0.5 lb ai/A (C) (FL nursery) 5.92 5.92 0.008 0.59

Potted ornamentals

– 1 app at 0.5 lb ai/A (C) (MI nursery) 13.90 13.89 0.019 1.4***

Potted ornamentals

– 1 app at 0.5 lb ai/A (C) (NJ nursery) 13.81 13.80 0.019 1.4***

Potted ornamentals

– 1 app at 0.5 lb ai/A (C) (OR nursery) 2.26 2.25 0.003 0.23

Potted ornamentals

– 1 app at 0.5 lb ai/A (C) (TN nursery) 9.37 9.34 0.013 0.93

Potted ornamentals

– 2 apps at 0.13 lb ai/A (C) (CA nursery) 0.41 0.41 0.001 0.041

Potted ornamentals

– 2 apps at 0.13 lb ai/A (C) (FL nursery) 2.92 2.92 0.004 0.29

Potted ornamentals

– 2 apps at 0.13 lb ai/A (C) (MI nursery) 6.97 6.97 0.010 0.70

Potted ornamentals

– 2 apps at 0.13 lb ai/A (C) (NJ nursery) 5.29 5.29 0.007 0.53

Potted ornamentals

– 2 apps at 0.13 lb ai/A (C) (OR nursery) 1.34 1.34 0.002 0.13

Potted ornamentals

– 2 apps at 0.13 lb ai/A (C) (TN nursery) 5.88 5.86 0.008 0.59

Acute RQ = use

- specific peak EEC / 719 μg ai/L (midge); chronic RQ = use

- specific 21

- day EEC / 10 μg ai/L (midge) *Exceeds the acute listed species LOC of 0.05 ***Exceeds the chronic species LOC of 1 A = foliar aerial application G = foliar ground application C = chemigation

### 115 Uses /Application Rate Peak EEC (μg/L) 21

- day

EEC (μg/L) Benthic

Invertebrate Acute RQ * Benthic

Invertebrate

Chronic

RQ *

S = seed treatment

E = Tier 1 GENEEC Model was used



### Aquatic Plants

Toxicity data for technical

- grade cyantraniliprole was non

- definitive for aquatic vascular

and non

- vascular plants. Thus

, risk quotients were not calculated. Further risk analysi s will be characterized in the Risk D escription section of the assessment.

2. Non

- target Terrestrial Animals

Birds

Cyantraniliprole is classified as ‘practically nontoxic’ to birds on an acute oral and sub

acute dietary exposure basis. Since all of the endpoints from the acute oral and sub

- acute dietary toxicity studies with birds are non

- definitive ( i.e ., they are ‘greater than’ values), they w ere not used to calculate RQs. Further description of the risks associated with

acute exposure to cyantr aniliprole can be found in the Risk Description section of the

document.

The chronic dietary

- based RQs range from < 0.01 to 0.45

. Foliar sprays, bark sprays, and seed treatment exposures were calculated using T

- REX while soil injection, soil drench, drip irrigation, and applications to p otted ornamentals were derived by estimating the concentration of cyantraniliprole in the leaf biomass of the plant ( Tables 38 and 39 ). Therefore, none of the avian RQs calculated for chronic exposure exceed the Agency’s

chronic risk LOC of 1.

Table 38

. Avian and M ammalian Foliar, Bark Spray, and Seed T reatment Chronic
Risk Q uotients

Feeding Category Avian chronic dietary

based RQs Mammalian chronic
dietary

- based RQs

Brassica leafy vegetables, leafy vegetables
2 apps at 0.175 lb ai/A and 1 app at 0.05 lb ai/A (7 days)

Short grass 0.08 4.02 *** Tall grass 0.04 1.84 *** Broadleaf plants 0.05 2.26 *** Fruits/pods 0.01 0.25 Arthropods 0.03 1.57 ***

Seeds 0.01 0.25
Brassica leafy vegetables, bushberries, leafy vegetables (except brassica), corm and tuberous

### 116 Feeding Category Avian chronic dietary

based RQs Mammalian chronic
dietary

- based RQs

vegetables, bulb vegetables

3 apps at 0.133 lb ai/A (5 days)

Short grass 0.09 4.35 *** Tall grass 0.04 1.99 *** Broadleaf plants 0.05 2.45 *** Fruits/pods 0.01 0.27 Arthropods 0.03 1.70 ***

Seeds 0.01 0.27

Citrus, cotton, oil seeds, pome fruit, stone fruit, tree nuts
3 apps at 0.133 lb ai/A (7 days)

Short grass 0.08 4.19 *** Tall grass 0.04 1.92 *** Broadleaf plants 0.05 2.36 *** Fruits/pods 0.01 0.26 Arthropods 0.03 1.64 ***

Seeds 0.01 0.26

Cucurbits, fruiting vegetables
2 apps at 0.175 lb ai/A and 1 app at 0.05 lb ai/A (5 days)

Short grass 0.08 4.22*** Tall grass 0.04 1.94*** Broadleaf plants 0.05 2.38*** Fruits/pods 0.01 0.26 Arthropods 0.03 1.65***

Seeds 0.01 0.26

Potatoes (seed treatment)

1 app at 0.69 lb ai/A

Seeds 0.45 N/A

Potatoes (seed treatment)

1 app at 0.176 lb ai/A

Seeds 0.11 N/A

Rapeseed including canola varieties, mustard seed (seed treatment)
1 app at 0.4 lb ai/A

Seeds 0.26 N/A

Sunflower (seed treatment)
1 app at 0.016 lb ai/A

Seeds 0.01 N/A

Flowerbeds and groundcovers
2 apps at 0.208 lb ai/A (7 days)

Short grass 0.09 4.67*** Tall grass 0.04 2.14*** Broadleaf plants 0.05 2.63***

### 117 Feeding Category Avian chronic dietary

based RQs Mammalian chronic
dietary

- based RQs

Fruits/pods 0.01 0.29 Arthropods 0.04 1.83***

Seeds 0.01 0.29

Ornamentals treated by commercial and consumer applicators

2 apps at 0.13 lb ai/A (7 days)

Short grass 0.06 2.92*** Tall grass 0.03 1.34*** Broadleaf plants 0.03 1.64*** Fruits/pods <0.01 0.18 Arthropods 0.02 1.14***

Seeds < 0.01 0.18

Ornamental plants, fruit and nut trees (non

- bearing) and forest seedlings grown in greenhouses,
lath and shade houses, containers, field nurseries and interiorscapes

1 app at 0.26 lb ai/A and 1 app at 0.16 lb ai/A (14 days)

Short grass 0.09 5.48*** Tall grass 0.04 2.51*** Broadleaf plants 0.05 3.09*** Fruits/pods 0.01 0.34 Arthropods 0.03 2.15***

Seeds 0.01 0.34

Ornamental plants (exterior landscapes and interior plantscapes), trees (including non

- bearing
fruit and nut trees) shrubs, evergreens, bedding plants, flowering plants, flowers, foliage plants,
groundcovers, vines, interior plantscape plants, vegetable transplants (fruiting, leafy, tuberous,
corm), public health insect control

1 app at 0.42 lb ai/A

Short grass 0.10 5.04*** Tall grass 0.05 2.31*** Broadleaf plants 0.06 2.84*** Fruits/pods 0.01 0.32 Arthropods 0.04 1.97***

Seeds 0.01 0.32

Turf, golf courses, residential lawns, commercial grounds, parks, playgrounds, athletic fields, sod
farms, grassy, weedy, mulched, or bare soil areas in and around greenhouses, nurseries, interior
plantscapes, lath and shade houses , under trees and shrubs that are being grown in

- ground

1 app at 0.26 lb ai/A and 1 app at 0.16 lb ai/A (30 days)

Short grass 0.07 4.84*** Tall grass 0.03 2.22*** Broadleaf plants 0.04 2.72*** Fruits/pods <0.01 0.30 Arthropods 0.03 1.90***

Seeds <0.01 0.30
Fly control bait (granular)

### 118 Feeding Category Avian chronic dietary

based RQs Mammalian chronic
dietary

- based RQs

5 apps at 0.087 lb ai/A (7 days)
Short grass 0.08 4.03*** Tall grass 0.04 1.85*** Broadleaf plants 0.05 2.27*** Fruits/pods 0.01 0.25 Arthropods 0.03 1.58***

Seeds 0.01 0.25
***Risk quotient exceeds chronic LOC of 1



### Table 39

. Summary of Avian and Mammalian Chronic RQs for Soil Injection/Soil Drench, Potted Ornamental D renc h, and Agricultural Drip I rrigation

Chronic Dietary RQ

Birds Mammals
Soil injection/drench hardwood 0.15 7.4*** Soil injection/drench hardwood 0.25 13*** Soil drench (citrus) 0.23 12*** Soil injection/drench softwood 0.07 3.4*** Soil injection/drench softwood 0.12 5.8***

Potted non

- woody ornamental

drench 0.005 0.23

Potted non

- woody ornamental

drench 0.009 0.45

Drip irrigation (brassica vegetables) 0.06 3.2***

Drip irrigation (cucurbits) 0.63 31.8*** Drip irrigation (fruiting vegetables) 0.18 9.1***

Drip irrigation (leafy vegetables) 0.05 2.7*** Drip irrigation (corm and tuberous vegetables) 0.06 3.2***

***Risk quotient exceeds chronic LOC of 1



### Mammals

Cyantraniliprole is classified as ‘practically nontoxic’ to mammals on an acute oral exposure basis. Since the endpoint from the toxicity study is non

- definitive ( i.e ., it is a ‘greater than’ value), it was not used to calculat e RQs. Further description of the risks associated with acute exposure to cyantran iliprole can be found in the R isk Description

section of the document.

Chronic risk quotients for the proposed f oliar spray, bark spray , and seed treatment uses

were calculated using T

- REX ( Table 38 ). Chronic RQs ranged from 0.18 to 5.48 for

these uses. Seed and fruits/pods were the only food items where RQ s did not exceed the

### 119 listed and non

- listed species chronic risk LOC (1); all other food items (short grass, tal l grass, broadleaf plants, and arthropods) exceeded.

Chronic risk quotients for s oil injection, soil drench, drip irrigation, and applications to potted ornamentals were derived by estimating the concentration of cyantraniliprole in

the leaf biomass of th e plant ( Table 39 ). Risk quotients ranged from 0.23 to 31.8. The proposed use on potted ornamental s was the only proposed use that did not exceed the

chronic risk LOC of 1.

Terrestrial Invertebrates

Cyantraniliprole is classified as “highly toxic” to non

- target terrestrial invertebrates on an acute exposure basis . Even though both the acute contact (LD 50 

### >0.093 μg ai/bee) and the acute oral (LD 50 

### >0.105 μg ai/bee) toxicity endpoints are non

- de finitive ; the classification

is based on the absolute valu e of the toxicity endpoint

. Risk quotients could not be calculated for acute exposures to cyantraniliprole though because the toxicity data were

non

- definitive. Further discussi on of this is presented in the R isk Description section. Toxicity data were also available for cyantraniliprole TEP and risk quotients were calculated for these. Most of the TEPs contain cyantraniliprole as the sole active ingredient; thus risk quotients were calculated for the most sensitive toxicit y endpoints. Several products are a mixture of two active ingredients: cyantraniliprole and thiamethoxam. The toxicity endpoints for this co

- formulation are much lower ( oral:

LD 50 

### =0.0062 μg ai/bee; contact: LD 50 

### =0.058 μg ai/bee) than for cyantraniliprol e

- only

TEPs (or the TGAI ) alone, so risk quotients were calculated for this product as well ( Table 40 )

.

The spray applications (foliage and bark) all yielded risk quotients that exceeded the LOC (0.4) that was identified in the recent white paper 2 

### that wa s reviewed by FIFRA Scientific Advisory Panel . The RQ values rang ed from 67 to 116 (dietary) and 2.4 to 9.2 (contact) for the cyantraniliprole

- only TEP and from 1260 to 2002 (dietary) and 27 to 75 (contact) for the cyantraniliprole/thiamethoxam TEP. Seed treatments (cyantraniliprole

only TEP) produced a risk quotient of 2.5, which exceeded the LOC. The risk quotients for soil applications of the cyantraniliprole

- only TEP did not exceed the LOC (ranged from 0.02 to 0.03); however, the drip irrigation scen ario for the cyantraniliprole/thiamethoxam TEP did exceed (RQ = 4.8). Overall, the results indicate that the TEPs for registration are of concern to bees for most of the proposed uses. Those TEPs formulated with thiamethoxam result in higher risk quotien ts than those formulated with cyantraniliprole alone.

2 USEPA 2013. White Paper in Suppor t of the Proposed Risk Assessme n t Process for Bees Submitted to the FIFRA Scientific Advisory Panel for Review and Comment. September 11

– 14, 2012 http://www.regulations.gov/#!documentDetail;D=EPA

- HQ

OPP

- 2012

- 0543

- 0004

### 120 Table 40 . Risk Quotients for C yantranili prole TEPs for I nsects

Use TEP (cyantraniliprole only) + TEP (cyantraniliprole and thiamethoxam) ++
Dietary Contact Dietary Contact
Brassica leafy vegetables, leafy vegetables 93 * 3.8 * 1735* 36 * Brassica leafy vegetables, bushberries, leafy vegetables (except brassica), corm and tuberous vegetables 100 * 2.4 * 1877* 75 *

Citrus, cotton, oil seeds, pome fruit, stone fruit, nut trees 97* 2.9 * N/A N/A

Cucurbits, fruiting vegetables 98* 7.7 * 1824* 73 * Flowerbeds and groundcovers 108* 4.5 * N/A N/A Ornamentals treated by commercial and consumer applicators 67* 2.8 * 1260* 27 *

Ornamental plants, fruit and nut trees (non

bearing) and forest seedlings grown in greenhouses, lath and shade houses, containers, field nurseries and interiorscapes 99* 5.7 * 1850* 54 *

Ornamental plants (exterior landscapes and interior plantscapes), trees (including non

bearing fruit and nut trees), shrubs, evergreens, bedding plants, flowering plants, flowers, foliage plants, groundcovers, vines, interior plantscape plants, vegetable transplants (fruiting, leafy, tuberous, corm), public health insect

control 116* 9.2 * N/A N/A

Turf, golf courses, residential lawns, commercial grounds, parks, playgrounds, athletic fields, sod farms, grassy, weedy, mulched, or bare soil areas in and around greenhouses, nurseries, interior plantscapes, lath and shade houses , under

trees and shrubs that are being grown in

ground 107* 5.7 * 2002* 54 *

Fly control bait 93* 5.5 * N/A N/A Ornamental trees and potted ornamentals (soil injection/drench) 0.02 N/A 0.32 N/A

Ornamental trees (soil injection/drench) 0.03 N/A N/A N/A Potted ornamentals (drench) 0.03 N/A N/A N/A Citrus (soil drench) 0.03 N/A N/A N/A Brassica vegetables, cucurbits, leafy vegetables, fruiting vegetables, corm and tuberous vegetables (drip irrigation) 0.03 N/A 0.48 * N/A

Potato, rape including canola, mustard seed, sunflower (seed treatment) 2.5 * N/A N/A N/A

N/A = not applicable

+ Oral LD 50 (0.116 μg ai/bee) is based on TEP with 20% ai and contact LD 50 (0.55 μg ai/bee) is based on TEP with 18.66% ai

++ Oral (0.0062 μg ai/bee) and contact (0.058 μg ai/bee) LD 50 s are based on TEP with 20% cyantraniliprole and 20% thiamethoxam

*Exceeds the acute LOC of 0.4



### Potential risk to bees from chronic exposure to cyantraniliprole could not be quantitatively assessed because of a lack of exposure data as well as toxicity data for

### 121 individual bees

. However, as discussed in the Risk Description section, there are a

number of semi

- field and full

- field studies that can be used to qualitatively assess potential risks to honeybee colonies.

3. N on

- target Terrestrial and Semi

- A quatic Plants

Risk quotients were calculated for listed terrestrial monocots and dicots ( Table 41 ) . None

of the RQ values exceeded the LOC of 1 ; thus, direct effects to listed dicots are not expected from the proposed cyantraniliprole uses. There is uncertainty regard ing the listed monocots because seedling emergence data from the most sensitive monocot in the vegetative vigor study ( onion) were not available (see Risk D escription for further discussion). Only non

- definitive data were available for the EC 25 

### values ; co nsequently, risk quotients for non

- listed monocots and dicots were not calculated for this endpoint

. See the Risk D escription section for further discussion.

Table 41 . Summary of Risk Quotient Values for Plants in Dry and Semi

- Aquatic

Areas E xposed t o C yantraniliprole t h rough R unoff and Spray D rift

Plant
Type Listed

Status Dry Semi

- Aquatic Spray Drift

Brassica vegetables (soil)
1 app at 0.35 lb ai/A

Monocot non

- listed N/A N/A N/A

Monocot listed <0.1 0.55 <0.1

Dicot non

- listed N/A N/A N/A

Dicot listed <0.1 0.55 <0.1
Brassica leafy vegetables, cucurbits, fruiting vegetables, leafy vegetables, (aerial spray)
1 app at 0.175 lb ai/A

Monocot non

- listed N/A N/A N/A

Monocot listed <0.1 0.33 0.13

Dicot non

- listed N/A N/A N/A

Dicot listed <0.1 0.33 < 0.1
Brassica leafy vegetables, cucurbits, fruiting vegetables, leafy vegetables, (ground spray)
1 app at 0.175 lb ai/A

Monocot non

- listed N/A N/A N/A

Monocot listed <0.1 0.27 <0.1

Dicot non

- listed N/A N/A N/A

Dicot listed <0.1 0.27 <0.1

Brassica leafy vegetables, bushberries, cotton, leafy vegetables (except brassica), oil seeds, pome fruit,
corm and tuberous vegetables, stone fruit, tree nuts, bulb vegetables, (aerial spray)
1 app at 0.133 lb ai/A

Monocot non

- listed N/A N/A N/A

Monocot listed <0.1 0.25 <0.1

Dicot non

- listed N/A N/A N/A

Dicot listed <0.1 0.25 <0.1
Brassica leafy vegetables, bushberries, citrus, cotton, leafy vegetables (except brassica), oil seeds, pome

### 122 Plant
Type Listed

Status Dry Semi

- Aquatic Spray Drift

fruit, corm and tuberous vegetables, stone fruit, tree nuts, bulb vegetables, (ground spray)
1 app at 0.133 lb ai/A

Monocot non

- listed N/A N/A N/A

Monocot listed <0.1 0.21 <0.1

Dicot non

- listed N/A N/A N/A

Dicot listed <0.1 0.21 <0.1
Citrus (chemigation)
1 app at 0.391 lb ai/A

Monocot non

- listed N/A N/A N/A

Monocot listed 0.20 0.73 0.29

Dicot non

- listed N/A N/A N/A

Dicot listed 0.20 0.73 0.15
Cucurbits, fruiting vegetables, potted ornamentals (drip chemigation/soil drench)
1 app at 0.130 lb ai/A

Monocot non

- listed N/A N/A N/A

Monocot listed <0.1 0.20 < 0.1

Dicot non

- listed N/A N/A N/A

Dicot listed <0.1 0.20 <0.1
Cucurbits, fruiting vegetables, leafy vegetables, (drip chemigation)
1 app at 0.35 lb ai/A

Monocot non

- listed N/A N/A N/A

Monocot listed <0.1 0.55 <0.1

Dicot non

- listed N/A N/A N/A

Dicot listed <0.1 0.55 <0.1

Potato (seed treatment)
1 app at 0.69 lb ai/A

– incorporation 3 inches

Monocot non

- listed N/A N/A N/A

Monocot listed <0.1 0.39 N/A

Dicot non

- listed N/A N/A N/A

Dicot listed <0.1 0.39 N/A

Potato (seed treatment)
1 app at 0.176 lb ai/A

– incorporation 3 inches

Monocot non

- listed N/A N/A N/A

Monocot listed <0.1 0.10 N/A

Dicot non

- listed N/A N/A N/A

Dicot listed <0.1 0.10 N/A
Rapeseed including canola varieties, mustard seed (seed treatment)
1 app at 0.4 lb ai/A

– no incorporation

Monocot non

- listed N/A N/A N/A

Monocot listed <0.1 0.63 N/A

Dicot non

- listed N/A N/A N/A

Dicot listed <0.1 0.63 N/A

### 123 Plant
Type Listed

Status Dry Semi

- Aquatic Spray Drift

Sunflower (seed treatment)
1 app at 0.016 lb ai/A

– 1 inch incorporation

Monocot non

- listed N/A N/A N/A

Monocot listed <0.1 <0.1 N/A

Dicot non

- listed N/A N/A N/A

Dicot listed <0.1 <0.1 N/A
Corm and tuberous vegetables (soil)
1 app at 0.25 lb ai/A

Monocot non

- listed N/A N/A N/A

Monocot listed <0.1 0.39 <0.1

Dicot non

- listed N/A N/A N/A

Dicot listed <0.1 0.39 <0.1
Flowerbeds and groundcovers (ground spray)
1 app at 0.208 lb ai/A

Monocot non

- listed N/A N/A N/A

Monocot listed <0.1 0.33 <0.1

Dicot non

- listed N/A N/A N/A

Dicot listed <0.1 0.33 <0.1

Ornamental plants, fruit and nut trees (non

- bearing), and forest seedlings grown in greenhouses, lath

and shade houses , containers, field nurseries, and interiorscapes, turf, golf courses, residential lawns,
commercial grounds, parks, playgrounds, athleti c fields, sod farms, grassy, weedy, mulched, or bare
soil areas in and around greenhouses, nurseries, interior plantscapes, lath and shade house , under trees
and shrubs that are being grown in

- ground (ground spray)
1 app at 0.26 lb ai/A

Monocot non

- listed N/A N/A N/A

Monocot listed <0.1 0.41 <0.1

Dicot non

- listed N/A N/A N/A

Dicot listed <0.1 0.41 <0.1
Ornamental plants (exterior landscapes and interior plantscapes), trees (including non

- bearing fruit and

nut trees), shrubs, evergreens, bedding plants, flowering plants, flowers, foliage plants, groundcovers,
vines, interior plantscape plants, vegetable transplants (fruiting, leafy corm, tuberous), public health
insect control (ground spray/soil drench)
1 app at 0.42 lb ai/A

Monocot non

- listed N/A N/A N/A

Monocot listed <0.1 0.66 <0.1

Dicot non

- listed N/A N/A N/A

Dicot listed <0.1 0.66 <0.1
Fly control bait (granular)
1 app at 0.087 lb ai/A

Monocot non

- listed N/A N/A N/A

Monocot listed <0.1 0.13 <0.1

Dicot non

- listed N/A N/A N/A

Dicot listed < 0.1 0.13 <0.1

### 124 Plant
Type Listed

Status Dry Semi

- Aquatic Spray Drift

Potted ornamentals (soil drench)
1 app at 0.5 lb ai/A

Monocot non

- listed N/A N/A N/A

Monocot listed 0.11 0.78 <0.1

Dicot non

- listed N/A N/A N/A

Dicot listed 0.11 0.78 <0.1

N/A

– RQ could not be calculated because of a non

- definitive EC 25 *Exceeds LOC of 1.



### B. Risk Description

1. Degradate Persistence and Accumulation

Although cyantraniliprole has several dissipation pathways, the degradates formed are mostly large in molecular weight (>344 g/mol) and similar in struc ture to the parent (Appendix C ). This indicates that the parent maybe undergoing a series of modifications rather than radical changes in structure. This conclusion is supported by o nly trace (<2%) amounts of mineral ization (CO 2 

### production) based on the submitted fa te studies. Aerobic soil metabolism studies show six of the eight major degradates have greater DT 50 

### values (more persistent) than the parent cyantraniliprole (Table 7 ). This persistence may

result in accumulation of these residues over time.

2. Risks to Aquatic Organisms

a. Animals

Fish The risk quotient analysis indicated that direct chronic effects to freshwater fish are not expected; none of the risk quotients exceeded the chronic risk LOC of 1. Risk quotients could not be calculated for acute exposures because the toxicity data were non

- definitive. In lieu of this, the most sensitive toxicity value can be compared with the peak EEC. In the case of freshwater fish, the most sensitive LC 50 

### ( >10000 μg total ai/L) ; although this

value is non

- definitive, it is much larger than the peak aquatic EEC of 37.97 μg ai/L. However, there was precipitate in this toxicity test and measured concentrations were not centrifuged or filtered; the amoun t of dissolved cyantraniliprole is unknown, lending uncertainty to the study’s results. The most sensitive definitive LC 50 

### for freshwater fish was 2400 μg ai/L, but was derived from a TEP study rather than a TGAI. It would be overly conservative to calculate risk quot ients from TEP toxicity data because the product

dissociates in water . However, i n this case, if a n RQ i s calculated from the peak aquatic EEC (37.97 μg ai/L) and the TEP LC 50 

### ( 2400 μg ai/L )

, it would be 0.016. This is well

below the a cute risk to listed species LOC of 0.05. Consequently, direct acute risks to freshwater fish and aquatic

- phase amphibians, for which fish serve as surrogates, from the proposed uses (TEP or TGAI) of cyantraniliprole are not considered likely. Indirect

ef

fects to freshwater fish and aquatic

- phase amphibians may still be possible for those

### 125 species that rely on aquatic invertebrates , terrestrial invertebrates, terrestrial monocots, estuarine/marine fish, and/or mam mals, for food, habitat, or other environmen tal

resources.

Risk quotients could not be calculated for direct acute effects to estuarine/marine fish because the toxicity value was non

- definitive. In lieu of this, the most sensitive toxicity value can be compared with the peak EEC. T he most sensiti ve LC 50 

### ( >1 2 000 μg total ai/L)

, although non

- definit i ve, is much larger than the peak aquatic EEC of 37.97 μg ai/L. There was precipitate in this toxicity test and measured concentrations were not centrifuged or filtered; therefore, the amount of dissolved cyantraniliprole is un certain

, lending uncer tainty to the study’s results. N o mortality or sub

- lethal effects were observed in any treatment group in the test. Furthermore, the LC 50 

### would need to be 1 6 times more sensitive ( 759 μg ai/L ) to even reach the acute risk to listed species LOC of 0.05. Thus, the likelihood of adverse effects on estuarine/marine fish from direct acute

exposure from the proposed uses of cyantraniliprole is considered low

.

Risk quotients could not be calculated for chro nic effects to estuarine/marine fish because only non

- definitive toxicity data were available. Given that the NOAEC was a less than value ( NOAEC <750 μg ai/L) , it is not possible to preclude the possibility of direct

chronic risks to estuarine/marine fish . Growth parameters (length and weight) were affected at the lowest concentration tested. Although the absolute value of the NOAEC (750 μg total ai/L) is one order of magnitude higher than the highest 60

- day aquatic EEC

o f 37.42 μg ai/L and risk concerns cannot be eliminated on this alone.

Indirect acute and chronic effects to estuarine/marine fish may be possible for those species that rely on aquatic invertebrates

, terrestrial invertebrates, terrestrial monocots, estuarine/marine fish, and/or mammals, for food, habitat, or other environmental

resources.

Invertebrates The risk quotient analysis using the TTR approach indicated direct effects to acute listed

and non

- listed species of freshwater invertebrates. Most of the proposed uses for cyantranilipro le exceeded the acute risk to listed species LOC of 0.05 while roughly 4%

of the proposed use scenarios evaluated did not. Of the former, roughly 55% o f the proposed use scenarios also exceeded the acute risk to non

- listed species LOC of 0.5

. Many (~68%) use scenarios also exceeded the chronic risk LOC of 1.

Acute toxicity data were available for 9 of the 10 degradates identified as degradates of concern. These data indicated that the degradates were less toxic than the parent, on an acute exposure ba sis. Likewise, the chronic toxicity value for the most toxic degradate also suggests the degradates are less toxic on a chronic exposure basis than the parent (Table 42 ). Therefore, the TTR approach for generating aquatic EECs is likely overly

conservati ve for freshwater invertebrates.

### 126 Table 42 . Comparison of Toxicological Data for Aquatic Invertebrates for Cyantraniliprole and its Degradates

Test material Molecular weight (g/mol) Endpoint Toxicity value (mg/L) Degradate toxicity expressed in parent compound equivalents (mg/L)*

Freshwater invertebrates ( Daphnia magna )
Cyantraniliprole 473

48

- hr EC 50 0.0204 0.0204

IN

- J9Z38 454 >0.22 >0.23

IN

- JCZ38 490 1.85 1.79

IN

- JSE76 491 26.64 25.7

IN

- K5A77 473 >0.85 >0.85

IN

- K5A78 473 >31.39 >31.39

IN

- K5A79 478 >31.57 >31.2

IN

- PLT97 460 0.30 0.31

IN

- QKV54 344 >0.287 >0.40

IN

- RNU71 437 >2.7 >2.9
Cyantraniliprole 473 NOAEC 0.00656 0.00656

IN

- J9Z38 454 0.24 0.25 **Degradate toxicity are in parent compound equivalents: (mg/L) = (MW parent / MW degradate ) x (toxicity endpoint of degradate (mg/L))



### To further refine the assessment, EECs were generated using a parent

- only approach for several of the cyantraniliprole use scenarios. Parent

- only EECs were generated for the

North Carolina cotton aerial application scenario ( 3 apps at 0.133 lb ai/A, 7

- day interval), which had yielded the highest EECs (38 μg ai/L) using the TTR approach. The new peak EEC was 7.89 μg ai/L and 21

- day EEC was 5.28 μg ai/L. This reduced the highest acute risk quotient for all use scenarios to 0.39; it still exceeds the acute listed species LOC of 0.05, but no longer exceeds the acute non

- listed species LOC of 0.5. Likewise, the highest chro nic risk quotient for all use scenarios was reduced to 0.80, well below the chronic LOC of 1. Further exploring acute exposures, it was determined that the peak EEC would need to be roughly 5.0 μg ai/L to result in an RQ below the acute listed species LOC of 0.05. This translates into roughly 20% of the use scenarios that exceeded the LOC (0.05) in the TTR approach. Thus, direct acute exposure risks are possible for

listed freshwater invertebrates; but direct chronic risks are not.

Indirect effects to f reshwater invertebrates are expected for those species that rely on aquatic invertebrates , terrestrial invertebrates, estuarine/marine fish, terrestrial monocots,

and/or mammals fo r food, habitat

, or other environmental resources.

The RQ analysis indicate d acute risk to listed species for estuarine/marine invertebrates for eight of the proposed cyantraniliprole use scenarios

. The highest risk quotient was 0.072 (compared with the LOC of 0.05); thus

, reducing the application rate may lower the risk quotie n ts for these eight use scenarios to below the acute risk to listed species

LOC (RQ < 0.05). None of the risk quotients exceeded the chronic risk LOC of 1 for

either the crustacean ( mysid shrimp mortality

- based endpoint) or mollusks (E astern oyster growth

- based endpoint); acute

- to

- chronic ratios are not normally based on acute growth endpoints, but the oyster shell toxicity test yielded the most sensitive endpoint for acute toxicity to estuarine/marine invertebrates

. Even when this more conservative

### 127 endpoi nt was considered (compared with the mysid acute mortal ity endpoint), RQ values

did not exceed the chronic risk LOC

. Consequently, direct acute e ffects to listed species

of estu arine/marine invertebrates are possible for a small number of proposed uses, but no direct chronic effects are expected. Indirect effects are expected for those species that rely on aquat ic invertebrates , terrestrial invertebrates, terrestrial monocots, estuarine/marine fish, and/or mammals f or food, habitat, or other envir onmental

resources.

The RQ analysis indicated potential chronic risks and limited direct acute risks for

benthic invertebrates. RQ values exceeded the chronic risk LOC of 1 in 46% of the modeled scenarios. Only one use exceeded the acute risk to listed species LOC of 0.05 ;

t he proposed rapeseed/mustard seed seed treatment (modeled by ND wheat) yielded a risk quotient of 0.051. The other rapeseed/mustard seed seed treatment

, evaluated using

the ND canola scenario

, did not exceed the acute risk to listed species LOC. The

maximum proposed application rate is 0.4 lb ai/A and it is possible that by s lightly lowering the application rate

, RQ values may drop below the acute risk to listed species LOC; however, direct chronic effects would still remain for roug hly half of the proposed uses. Indirect effects are possible for those species that rely on aquatic inv ertebrates

, terrestrial invertebrates, estuarine/marine fish, terrestrial monocots, and/or mammals f or food or other environmental resources.

b. Plants

Risk quotients for aquatic plants could not be calculated because the toxicity values were

non

- definitive. The most sensitive vascular aquatic plant EC 50 

### is >12100 μg ai/L (duckweed)

. T he most sensitive non

- vascular plant test ( EC 50 

### >10000 μg total ai/L ) was with an estuarine/marine diatom and contained precipitate in the highest concentration

tested . T here is uncertainty as to the actual amount of cyantraniliprole that was dissolved

in the test solution because measured concentrations were not centrifug ed or filtered

. The next most sensitive toxicity value (no precipitate in the study) was for green algae (EC 50 

### >13000 μg ai/L). T he duckweed, estuarine/marine diatom, and green algae toxicity

values are all much larg er than the peak surface water EEC pre dicted for all of the proposed uses of cyantraniliprole (37.97 μg ai/L). In addition to technical

- grade cyantraniliprole, toxicity studies with non

- vascular plants were performed with typical

end

- use products (TEP). Such a study with green algae yielded the most sensitive EC 50 

### of all the non

- vascular plant studies ( EC 50 

### = 825 μg ai/L ) . Using the highest peak EEC (37.97 μg ai/L) and the TEP toxicity endpoint, the resulting RQ is 0.046 and is well below the LOC of 1 for aquatic plants. Normally results fr om TEP studies are not considered in aquatic assessments because they are overly conservative (organism is expected to be exposed to individual components and not the full formulation itself). Given the lines of evidence, it is unlikely that there will be direct adverse effects to aquatic plants based on exposure from the proposed uses of cyantraniliprole. Indirect effects are possible for those species that rely on aquatic invertebrates , terrestrial invertebrates, terrestrial monocots, estuarine/marine fish, and/or mammals, for habitat modification, seed/propagule dispersal, or other environmental resources.

### 128 3. Risks to Terrestrial Organisms

a. Animals

Birds , Reptiles, and Land

- Phase Amphibians

Acute dose

- based and dietary

- based risk quotients could not be calculated to evaluate the risks to birds because only non

- definitive acute toxicity data were available. Instead, the

non

- definitive toxicity values were directly compared to the EECs ( Table 43 ). The most sensitive TGAI studies were selected (in two cases, there were more sensitive results for TEP studies, but these were also non

- definitive and the lower toxicity value is probably

an artifact of the largest dose of product that was given to the bir d rather than the active ingredient itself). In all cases, none of the EECs were larger than the non

- definitive toxicity values for the most sensitive avian species

. No sub

- lethal effects were observed

in either the acute oral or sub

- acute dietary studies for any of the species tested.

An LD 50 

### /ft 2 

### analysis is usually conducted for gr anular pesticide applications; however, risk quotients cannot be calculated when toxicity values are non

- definitive. This process is in place because using the absol ute value of the non

- definitive may over

- estimate risk. In this case, given that no other information was available, the absolute value of the acute oral bird toxicity (LD 50 

### =2250 mg ai/kg

- bw) was used in T

- REX to generate risk quotients which ranged from <0.01 to 0.03. These risk quotients cannot be used quantitatively in a risk assessment because they were calculated in an overly conservative manner; however, they qualitatively demonstrate that acute risks to birds for the proposed public health granula r use of cyantraniliprole are unlikely

. Thus, the potential for risk is

considered to be low for acute dose

- based and dietary

- based exposure of birds, reptiles,

and terrestrial

- phase amphibians from cyantraniliprole for all registered uses.

None of the avian RQ value s calculated for chronic exposure exceed the Agency’s

chronic risk LOC for listed and non

- listed species. Therefore, the likelihood of chronic

adverse effects in birds , reptiles, and terrestrial

- phase amphibians from exposure to
residues fr om the proposed cyantraniliprole uses is expected to be low

.

Indirect effects are possible for species of birds, reptiles and terrestrial

- phase amphibians that rely on aquatic invertebrates, terrestrial invertebrates, terrestrial monocots,

estuarine/marin e fish, and/or mammals for food or other environmental resources.

Table 43 . Comparison of the H ighest Calculated EEC for Each U se of

C yantraniliprole to the Most Sensitive Avian Acute Toxicity V alues

Application Scenario Dietary

Item EEC (mg ai/kg

- bw) LD 50 ( zebra

finch and

bobwhite quail ) mg ai/kg

- bw EEC (mg ai/kg

- diet) LC 50 (mallard

and bobwhite

quail ) mg ai/kg

- diet

Brassica leafy vegetables, leafy vegetables Short

grass 91.56 >2250 80.39 >5620

### 129 Application Scenario Dietary

Item EEC (mg ai/kg

- bw) LD 50 ( zebra

finch and

bobwhite quail ) mg ai/kg

- bw EEC (mg ai/kg

- diet) LC 50 (mallard

and bobwhite

quail ) mg ai/kg

- diet

Brassica leafy vegetables, bushberries, leafy vegetables (except brassica), corm and tuberous vegetables, bulb vegetables Short

grass 99.10 >2250 87.02 >5620

Citrus, cotton, oil seeds, pome fruit, stone fruit, tree nuts Short

grass 95.55 >2250 83.90 >5620

Cucurbits, fruiting vegetables Short

grass 96.23 >2250 84.49 >5620

Potatoes (seed treatment

– higher rate) Seed 113.65 >2250 N/A >5620

Potatoes (seed treatment

– lower rate) Seed 28.99 >2250 N/A >5620

Rapeseed including canola varieties, mustard seed (seed treatment) Seed 65.88 >2250 N/A >5620

Sunflower (seed treatment) Seed 2.64 >2250 N/A >5620

Flowerbeds and groundcovers Short

grass 106.35 >2250 93.38 >5620

Ornamentals treated by commercial and consumer applicators Short

grass 66.47 >2250 58.36 >5620

Ornamental plants, fruit and nut trees (non

- bearing) and forest seedlings grown in greenhouses, lath and shade houses, containers, field nurseries and interiorscapes Short

grass 97.59 >2250 85.64 >5620

Ornamental plants (exterior landscapes and interior plantscapes), trees (including non

- bearing fruit and nut trees), shrubs, evergreens, bedding plants, flowering plants, flowers, foliage plants, groundcovers, vines, interior plantscape plants, vegetable t ransplants (fruiting, leafy, tuberous, corm), public

health insect control Short

grass 114.80 >2250 100.80 >5620

Turf, golf courses, residential lawns, commercial grounds, parks, playgrounds, athletic fields, sod farms, grassy weedy mulched, or bare soil areas in and around greenhouses, nurseries, interior plantscapes, lath and

shade houses , under trees and shrubs that are being grown in

- ground Short

grass 82.97 >2250 72.85 >5620

Soil injection/drench hardwood (lower rate) Leaves N/A >2250 148 >5620

Soil injection/drench hardwood (higher rate) Leaves N/A >2250 254 >5620

Soil drench (citrus) Leaves N/A >2250 233 > 5620

Soil injection/drench softwood (lower rate) Leaves N/A >2250 68 >5620

Soil injection/drench softwood (higher rate) Leaves N/A >2250 116 >5620

### 130 Application Scenario Dietary

Item EEC (mg ai/kg

- bw) LD 50 ( zebra

finch and

bobwhite quail ) mg ai/kg

- bw EEC (mg ai/kg

- diet) LC 50 (mallard

and bobwhite

quail ) mg ai/kg

- diet

Potted non

- woody ornamental drench (lower rate) Leaves N/A >2250 4.6 >5620

Potted non

- woody ornamental drench (higher rate) Leaves N/A >2250 9 >5620

Drip irrigation (brassica vegetables) Leaves N/A >2250 64 >5620

Drip irrigation (cucurbits) Leaves N/A >2250 636 >5620

Drip irrigation (fruiting vegetables) Leaves N/A >2250 182 >5620

Drip irrigation (leafy vegetables) Leaves N/A >2250 54 >5620

Drip irrigation (corm and tuberous vegetables) Leaves N/A >2250 64 >5620



### Mammals

Acute dose

- based and dietary

- based risk quotients could not be calculated to evaluate the

risks to mammals because only non

- definitive acute toxicity data were available. Instead,

the non

- definitive toxicity values were directly compared to the EECs ( Table 44 ). In all cases, none of the EECs were larger than the non

- definitive toxicity values. Furthermore,

no sub

- lethal effects were observed in the acute oral toxicity study

.

An LD 50 

### /ft 2 

### analysis is usually conducted for granular pesticide applications; however, similar to what was discussed for birds, risk quotients cannot be calculated when toxicity

values are non

- definitive. In this case, given that no other information was available, the absolute value of the acute oral mammal toxicity (LD 50 

### =5000 mg ai/kg

- bw) was used in

T

- REX to generate RQs . Th e RQs ranged from <0.01 to 0.01. These RQs cannot be used quantitatively in a risk assessment because they were calculated in an overly conservative manner; however, they qualitatively demonstrate that acute risks to

mammals f rom the proposed public healt h granular use of cyantraniliprole are consider ed unlikely

. T hus, the potential for risk is considered to be low for acute dose

- based exposure of mammals from cyantraniliprole for all proposed uses.

Chronic risk quotients exceeded the chronic risk to ma mmals LOC of 1 for most of the proposed uses of cyantraniliprole. The few uses that did not exceed were: non

- woody potted ornamental plants, and the seed treatments (potato, rapeseed/mustard seed, and sunflower). Of the uses that exceeded, mammals that consume short grass, tall grass, broadleaf plants, and art hropods are potentially at direct risk. Those mammals that strictly consume seeds, fruits, and/or pods are not expected to be at direct risk from cyantraniliprole uses. Consequently, direct chroni c risks are possible for most cyantraniliprole uses, based on the screening

- level RQ analysis.

### 131 Indirect effects to mammals are possible for all species that rely on aquatic invertebrates, terrestrial invertebrates, terrestrial monocots, mammals, and/or es tuarine/marine fish for

food , habitat, or other environmental resources.

Table 4 4 . Comparison of the Highest Calculated EEC for Each U se of

C yantraniliprole to the Most S ensitive M ammal Acute Toxicity V alue

Application Scenario Dietary

Item EEC
(mg ai/kg

- bw) LD 50 ( rat ) mg
ai/kg

- bw

Brassica leafy vegetables, leafy vegetables Short grass 76.65 >5000

Brassica leafy vegetables, bushberries, leafy vegetables (except
brassica), corm and tuberous vegetables, bulb vegetables Short grass 82.96 >5000

Citrus, cotton, oil seeds, pome fruit, stone fruit, tree nuts Short grass 79.99 >5000

Cucurbits, fruiting vegetables Short grass 80.56 >5000

Potatoes (seed treatment

– higher rate) Seed 95.14 >5000

Potatoes (seed treatment

– lower rate) Seed 24.27 >5000

Rapeseed including canola varieties, mustard seed (seed
treatment) Seed 55.15 >5000

Sunflower (seed treatment) Seed 2.21 >5000

Flowerbeds and groundcovers Short grass 89.03 >5000

Ornamentals treated by commercial and consumer applicators Short grass 55.64 >5000

Ornamental plants, fruit and nut trees (non

- bearing) and forest
seedlings grown in greenhouses, lath and shade houses,
containers, field nurseries and interiorscapes Short grass 81.70 >5000

Ornamental plants (exterior landscapes and interior plantscapes),
trees (including non

- bearing fruit and nut trees), shrubs,

evergreens, bedding plants, flowering plants, flowers, foliage
plants, groundcovers, vines, interior plantscape plants, vegetable

t ransplants (fruiting, leafy, tuberous, corm), public health insect

control Short grass 96.11 >5000

Turf, golf courses, residential lawns, commercial grounds, parks,
playgrounds, athletic fields, sod farms, grassy weedy mulched, or
bare soil areas in and around greenhouses, nurseries, interior
plantscapes, lath and shade houses , under trees and shrubs th at are being grown in

- ground Short grass 88.40 >5000

Soil injection/drench hardwood (lower rate) Leaves 141 >5000

Soil injection/drench hardwood (higher rate) Leaves 241 >5000

Soil drench (citrus) Leaves 221 >5000

Soil injection/drench softwood (lower rate) Leaves 65 >5000

### 132 Application Scenario Dietary

Item EEC
(mg ai/kg

- bw) LD 50 ( rat ) mg
ai/kg

- bw

Soil injection/drench softwood (higher rate) Leaves 110 >5000

Potted non

- woody ornamental drench (lower rate) Leaves 4 >5000

Potted non

- woody ornamental drench (higher rate) Leaves 9 >5000

Drip irrigation (brassica vegetables) Leaves 61 >5000

Drip irrigation (cucurbits) Leaves 604 >5000

Drip irrigation (fruiting vegetables) Leaves 173 >5000

Drip irrigation (leafy vegetables) Leaves 51 >5000

Drip irrigation (corm and tuberous vegetables) Leaves 61 >5000



### Terrestrial Invertebrates

Toxicity data were available for parasitic wasps, beetles, spiders, lacewings, predatory mites, and collembola. The studies indicated that cyantraniliprole is toxic to some

terrestrial invertebrates at very low application rates ( 48

- hr LR 50 

### = 0.00 008 lb ai/A

– parasitic wasp ). Conversely, collembola, which are exposed to cyantraniliprole through direct contact with the soil, were not found to be very sensitive to applications of cyantraniliprole (EC 50 

### > 1200 mg ai/kg

- soil. Likewise, earthw orms demonstrated a low toxic effect to cyantraniliprole (EC 50 

### > 102.6 mg ai/kg

- soil

– based on TEP ).

Honeybee t oxicity data for cyantraniliprole indicated that it is highly toxic on an acute

oral and contact basis , but the endpoints were non

- definitive and the true toxicity

classification is uncertain

. Tier I r isk quotients for TEPs (cyantraniliprole

- only and cyantraniliprole

- thiamethoxam) exceeded the LOC of 0.4 for most uses. Risk quotients could not be calculated using data from technical

- grade cyan traniliprole because the oral and contact toxicity endpoints were both non

- definitive. In lieu of this, Table 45 presents a direct comparison of the EEC for each use with the toxicity endpoint. For technical

grade cyantraniliprole , the EEC is higher than the non

- definitive toxicity value for all uses except the soil applications . This indicates that those uses may pose environmental

risk s to terrestrial insects. There is uncertainty, however, because the toxicity endpoints

are non

- definitive.

Table 45

. Comparison of the EEC for Each U se of C yantraniliprole to the Most

S ensitive H oneybee Acute Toxicity V alues

Application Scenario Dietary EEC
(μg ai/bee ) Oral LD 50 μ g
ai/ bee Contact EEC
(μg ai/bee ) Contact L D 50

μ g ai/ bee

Brassica leafy vegetables, leafy
vegetables 10.76 > 0.1055 2.11 1 > 0.0934

### 133 Application Scenario Dietary EEC
(μg ai/bee ) Oral LD 50 μ g
ai/ bee Contact EEC
(μg ai/bee ) Contact L D 50

μ g ai/ bee

Brassica leafy vegetables, bushberries,
leafy vegetables (except brassica), corm
and tuberous vegetables, bulb vegetables 11.64 > 0.1055 4.36 > 0.0934

Citrus, cotton, oil seeds, pome fruit,

stone fruit, tree nuts 11.23 > 0.1055 1.6 2 > 0.0934

Cucurbits, fruiting vegetables 11.31 > 0.1055 4.24 > 0.0934

Potato , rapeseed including canola,
mustard seed, sunflower (seed

treatment ) 0.292 > 0.1055 N/A > 0.0934

Flowerbeds and groundcovers 12.50 > 0.1055 2.50 3 > 0.0934

Ornamentals treated by commercial and
consumer applicators 7.81 > 0.1055 1.56 4 > 0.0934

Ornamental plants, fruit and nut trees
(non

- bearing) and forest seedlings
grown in greenhouses, lath and shade

houses, containers, field nurseries and
interiorscapes 11.47 > 0.1055 3.13 5 > 0.0934

Ornamental plants (exterior landscapes
and interior plantscapes), trees
(including non

- bearing fruit and nut
trees), shrubs, evergreens, bedding
plants, flowering plants, flowers, foliage
plants, groundcovers, vines, interior
plantscape plants, vegetable transplants
(fruiting, leafy, tuberous, corm), public

health insect control 13.49 > 0.1055 5.05 > 0.0934

Turf, golf courses, residential lawns,
commercial grounds, parks,
playgrounds, athletic fields, sod farms,
grassy weedy mulched, or bare soil
areas in and around greenhouses,
nurseries, interior plantscapes, lath and

shade houses , under trees and shrubs

th at are being grown in

- ground 12.41 > 0.1055 3.13 5 > 0.0934

Fly control bait (granular) 10.79 > 0.1055 3.01 6 N/A

Ornamental trees and potted
ornamentals (s oil injection/drench )
(lower rate) 0.002 > 0.1055 N/A N/A

Ornamental trees (s oil injection/drench )
(higher rate) 0.003 > 0.1055 N/A N/A

Citrus (s oil drench ) 0.003 > 0.1055 N/A N/A

Potted ornamental drench (higher rate) 0.004 > 0.1055 N/A N/A

Brassica vegetables, cucurbits, fruiting
vegetables, leafy vegetables, corm and
tuberous vegetables (drip irrigation) 0.003 > 0.1055 N/A N/A

### 134 Application Scenario Dietary EEC
(μg ai/bee ) Oral LD 50 μ g
ai/ bee Contact EEC
(μg ai/bee ) Contact L D 50

μ g ai/ bee

N/A = not applicable

1 Based on single app of 0.175 lb ai/A because application interval is >5 days

2 Based on single app of 0.133 lb ai/A because application interval is >5 days

3 Based on single app of 0.208 lb ai/A because application interval is >5 days

4 Based on single app of 0.13 lb ai/A because application interval is >5 days

5 Based on single app of 0.26 lb ai/A because application interval is >5 days

6 Based on single app of 0.087 lb ai/A because application interval is >5 days



### Toxicity in formation was available for three of cyantraniliprole’s degradates . Two of them (IN

- HGW87 and IN

- J9Z38) are classified as “highly toxic” to honeybees , but there is uncertainty regarding this classification because the endp oints were non

- definitive.

T he third degradate (IN

- K5A78) is classified as “practically non

- toxic” to honeybees. Based on this information, it is uncertain as to whether cyantraniliprole ’s degradates may

pose a risk to honeybees.

Residue data were als o available for cyantraniliprole and some of its degradates in honey, poll en, nectar, wax, and guttation fluid

. Residue samples were taken as part of semi

- or full

- field studies with honeybees. Pollen, nectar, and wax were collected from the hives

or dir ectly from foraging bees. Guttation water samples were collected from the crop that had been treated with cyantraniliprole. After c onverting the residues into dose s , the y could be directly compared to the oral and contact toxicity values (it should be no ted that the toxicity values were non

- definitive and taking them at face value may o ver

- estimate the risk) ( Table 46 ). Comparing the measured residue data to the model

- estimated exposure values on food items, the foliar model (T

- REX) yielded much higher e stimates than quantified in the field. T

- REX EECs (converted into a dose per bee) ranged from 7.81 to 13.49 μg ai/bee for dietary exposure and 1.56 to 5.05 μg ai/bee for contact exposure. The highest residue measurement in the field (converted into a dos e per bee) was 0.0083 μg ai/bee. For drench/soil applications, the modeled EECs (converted into a dose per bee) were 0.002 to 0.007 μg ai/bee for dietary exposure whereas the maximum residue measured in the field for drip irrigation application methods wa s 0.003 μg ai/bee

in nectar. This suggests that risk quotients based off of T

- REX (foliar applications) may

over

- estimate the exposure potential for honeybees, and thus the risk. The risk quotients for drench/soil application methods may more accurately represent exposure conditions,

and thus risk.

There was one instance in which the detection of cyantraniliprole in the field surpassed

the absolute acute contact and oral LD 50 

### value s : guttation fluid in a study with two foliar applications of cyantraniliprole at 0.08 lb ai/A on oilseed rape. This establishes that conditions in the field are such that concentrations of cyantraniliprole can reach concentrations potentially hazardous for acute exposures to honey bees

. The data set in

Table 46 is very limited; o ilseed rape is the only crop tested for foliar applications. Application rates vary; howev er, guttation fluid , which yield ed the highest concentrations of cyantraniliprole compared to other food items, is only measur ed at the 0.08 lb ai/A

rate. It is plausible that the 0.134 lb ai/A rate would yield even higher concentrations of

cyan traniliprole in guttation fluid

. T his rate is still lower than 0.175 lb ai/A, which is the

### 135 maximum rate for a number of crops, and also lower than several proposed flowerbed/ornamental foliar uses that range from 0.208 to 0.42 lb ai/A. This means that field concentrations may be higher than these studies documented for application rate s of 0.175, 0.208, and 0.42 lb ai/A. Furthermore, th e label stipulates that applications can be made every 7 days for most crops and the study’s foliar scenarios were based on application intervals of 15 days or more. Again, residues may be higher with more frequent application intervals. G uttation fluid is considered a minor exposure pathway

because of the uncertainty regarding its availability (generally mornings only) and honeybees may obtain most of their water requirements through other food sources (USEPA 2012b)

. Therefore, the analyses that follow focus on pollen and nectar residue

data.

One drip irrigation scenario ( 0.089 lb ai/A with melons) was also considered in the

residue studies and generally yielded lower concentrations of cyantraniliprole in pollen, and guttation fluids than the foliar app lication methods ; however, it should be noted that the application rate used in the study was much lower than the maximum single application rate of 0.35 lb ai/A for drip chemigation in some crops

.

Table 46 . R esidues of Cyantraniliprole and Its Degradates in Bee Food I tems

Application rate (lb ai/A) Cyantraniliprole residues in mg ai/kg ( converted into a

dose

– μg ai/bee) 1 Other degradates in mg ai/kg ( converted into a dose

– μg/ bee) 1 MRID

Oilseed rape (foliar)

2 at 0.08 (20 days) Honey = 0.013 ( 0.0017 )

Pollen = 0.019 ( 0.0024 )

Wax = 0.033 ( 0.0043 )

Guttation = 3.092 ( 0.40 ) * Guttation

IN

- J9Z38 = 0.046 ( 0.0059 )

IN

- HGW87 = 0.010 ( 0.0012 )

IN

- MYX98 = 0.008 ( 0.00098 ) 48122557

Oilseed rape (foliar)

2 at 0.08 (16 days) Honey = 0.020 ( 0.0025 )

Pollen = 0.065 ( 0.0083 )

Wax = 0.030 ( 0.0038 )

Guttation = 0.647 ( 0.083 ) Guttation

IN

- J9Z38 = 0.012 ( 0.0015 )

IN

- HGW87 = 0.008 ( 0.0010 )

IN

- MYX98 = 0.007 ( 0.0009 ) 48122558

Oilseed rape (foliar)

2 at 0.134 (15 days) Pollen (median) = 0.025 ( 0.0032 ) Honey = 0.005 ( 0.00068 ) Not available 48122553

Oilseed rape (foliar)

2 at 0.011 (15 days) Pollen (median) = 0.011 ( 0.0014 )

Wax = 0.008 ( 0.00097 ) Not available 48122553

Oilseed rape (foliar)

2 at 0.134 Honey = 0.005 ( 0.00064 )

Pollen = 0.077 ( 0.0099 ) Pollen

IN

- J9Z38 = 0.007 ( 0.00093 ) and 0.010 ( 0.0012 ) 48122552

Oilseed rape (foliar)

2 at 0.011 (17 days) Pollen = 0.042 ( 0.0054 ) Not available 48122552

Oilseed rape (foliar) Honey (median) = 0.006 ( 0.00073 ) Not available 48122551

### 136 2 at 0.011 (15 days) Pollen = 0.009 ( 0.0012 )

Wax = 0.011 ( 0.0014 )

Oilseed rape (foliar)

2 at 0.134 (15 days) Honey (median) = 0.008 ( 0.0010 )

Pollen = 0.062 ( 0.0080 )

Wax = 0.017 ( 0.0021 ) Not available 48122551

Melon (drip irrigation)

3 at 0.089 (7 days) Pollen = 0.012 ( 0.0015 )

N ectar = 0.026 ( 0.0033 )

Guttation = 0.066 ( 0.0084 ) Not available 48122548

1 Conversions to ai/bee were made by multiplying the residue value (converted to mg ai/kg) times the body weight of an average

- sized adult bee (0.128 g) (Mayer and Johansen 1990). *Exceeds cyantraniliprole acute contact (LD 50 >0.0934μg ai/bee) and/or acut e oral (LD 50 >0.1055 μg ai/bee) toxicity value



### Some data from magnitude of residue studies were also available for pollen (MRIDs

48119994 and 48120013 ) (Table 47 )

. These studies were not performed in conjunction with a honeybee semi

- or full

- field experiment. In these studies, samples of pollen were collected from each crop after a period of time following the application of cyantraniliprole. Canola, sunflower, tom ato, zucchini and P

. tanacetifolia were tested

and both foliar and drench application scenarios were considered . Foliar applications consisted of multiple application s of 0.12 lb ai/A applied at 7

- 10 day intervals while soil applications were applied once at a rate of 0.35 lb ai/A. Cyantraniliprole r esidues in pollen ranged from 0.016 to 5.549 mg ai/kg for foliar applications 0.023 to 1.674 mg ai/kg for soil applications. In all instances but zucchini, the soil application yielded lower

residue values th an the foliar applications

. Some of the f oliar applications were made during bloom; thus, the higher concentrations of residues detected on the pollen for foliar applications probably reflects cyantraniliprole coming into direct contact with the pollen. The soil drench applications reflect solely movement of the insecticide from the soil into the plant. Comparing the cyantrani li prole residues detected in pollen and anthers, it appears that cyantrani li prole is not equally distributed throughout the flower ; residue concentrations are consistently higher in pollen samples than anther samples.

### 137 Table 47

. Summary of Pollen Residue Data from Magnitude of Residue Studies

Total radioactive residues (mg/kg)

Crop Canola Sunflower Tomato Zucchini Phacelia tanacetifolia

Treatment Foliar a Soil b Foliar a Soil b Foliar a Soil c Foliar a Soil b Foliar a Soil b

Pollen d 0.346 0.268 5.549 0.136 1.674 0.101 0.016 0.023 0.069 0.033

Anthers d 0.125 0.014 0.488 0.262 0.467 0.048 0.008 0.002 0.015 0.015

Anther wash e 0.082 0.014 0.081 0.045 0.134 0.019 0.009 0.004 0.049 0.021

a Three foliar applications of [14C]

- cyantraniliprole were made at 0.12 lb ai/A, ca. 7 to 10 days apart, with the first application at ca. 3 to 4 weeks prior to flowering. The last foliar application to canola was 2 days after the second application to ensure completion of the treatment regime before onset of flowering.

b A single 0.35 lb ai/A soil drench application of [14C]

- cyantraniliprole was made at sowing.

c A single 0.35 lb ai/A soil drench applic ation of [14C]

- cyantraniliprole was made at ca. 3 to 4 weeks prior to flowering.

d TRR = Total extractable + unextracted 14C

- residues in sample

e A water rinse, required to separate pollen from the anthers, was analyzed by LSC



### Given that acute risks were identified for cyantraniliprole applications, the residue data

taken from hives were used to refine the risk assessment. Oral consumption rates of pollen and nectar are dependent on the life stage of the honeybee [ guttation wat er is not considered here because exposures are expected to be higher for other food items ( i.e

., pollen and nectar) (USEPA 2012b)] . Larval toxicity data are not available for cyantraniliprole, thus only adults are considered here. Table 48 depicts the expected food consumption rate for different adult honeybees. To calculate risk quotients, the estimated dose per day for each food item is divided by the oral toxicity value. Risk quotients were calculated using the oral dose for a TEP because t his valu e was definitive , whereas the toxicity endpoints for technical

- grade cyantraniliprole were not ( Table 49 )

. This is a conservative approach because some of the toxicity of a product may be associated with

it non

- cyantraniliprole components. However, given that the TGAI data for cyantraniliprole are non

- definitive and not appropriate for risk quotient calculation, the TEP data are used, with caution.

Table 48

. Estimated Consumption Rates of Pollen, Nectar and Royal Jelly by Adult

H oneybees

Life Stage Caste Daily consumption rate (mg/day)

Average Age

(in days) Brood food / royal jelly Nectar ** Pollen *** Total food

Adult Worker (cell cleaning and capping) 0

- 10 none 60 5.2 65

Worker (brood and queen tending, nurse bees) 6

- 17 none 140 8.85 149

Worker (comb building, cleaning and food handling) 11

- 18 none 60 1.7 62

### 138 Life Stage Caste Daily consumption rate (mg/day)

Average Age

(in days) Brood food / royal jelly Nectar ** Pollen *** Total food

Worker (foraging for pollen) >18 none 43.5 0.041 44

Worker (foraging for nectar) >18 none 292 0.041 292

Worker (maintenance of hive in

winter 0

- 90 none 29 2 31

Drone >10 none 235 0.0002 235

Queen 0+ u nknown unknown None unknown

Source : USEPA 2012 Draft Pollinator Risk Assessment Framework; NA = not applicable

*From Winston 1987

**From Rortais et al. 2005. Assumes that average sugar content of nectar is 30%.

*** From Crailsheim et al. (1992, 1993).



### Table 49

. Refined Acute Oral R isk Quotients for Adult Honeybees Using Maximum Reported Concentrations in Pollen and N ectar

Life Stage Cast/Task Average Age (d) Total food Consumption ( g/d) Estimated Oral

Dose (ug ai/bee/d) 1 Acute RQ 2

Cyan. only

Adult Worker (cell cleaning and capping) 0

- 10 0.0 65 0.001 96 

### 0.017

Worker (brood and queen tending, nurse bees) 6

- 17 0. 149 0.00 432 

### 0.037

Worker (comb building, cleaning and food handling) 11

- 18 0.0 62 0.00 169 

### 0.015

Worker (foraging for pollen) >18 0.0 435 0.00 113 

### 0.010

Worker (foraging for nectar) >18 0. 292 0.00 76 

### 0.066

Worker (maintenance of

hive in winter 0

- 90 0.0 31 0. 000 908 

### 0.008

Drone >10 0. 235 0.006 11 

### 0.053

Queen 0+ unknown unknown unknown

1 Oral dose determined using maximum concentrations of cyantraniliprole in pollen ( rapeseed = 0.077 mg/kg) and nectar ( melon = 0.026 mg/kg) reported in Table 4 6 multiplied by the estimated

cast

- specific consumption rate. The dose is reflective of the percent po llen and nectar that adult honeybees typically consume in a day ( i.e., for nectar, the maximum concentration found in nectar is multiplied by the nectar consumption rate. The same is done for pollen and these are then added together for the total cyantraniliprole consumption rate).

2 Acute RQs determined as the ratio of ora l dose to the acute LD 50 for cyantranilip role

- only TEP (0.116 μg ai/bee)

### 139 The concentrations of re sidues detected in hives in the semi

- and full

- field studies indicate that the use of cyantraniliprole products r esult in residues that are not expected to

r esult in risk concerns to honeybees through the dietary exposure route. The highest concentration of cyantraniliprole in pollen was detected in samples taken directly from the hive (comb). The highest concentration of cyantraniliprole in nectar was colle cted from forager bees upon their return to the hive. The risk quotients are most heavily influenced by the concentration of cyantraniliprole in nectar because this is a larger part of the bee’s diet than pollen

. One uncertainty is that the residue sampl es were taken from studies that were far below the maximum application rate; higher application rates may result in higher residue concentrations in nectar and pollen. The highest cyantraniliprole

concentration in nectar was derived from a s tudy with 3 ap plications of cyantraniliprole at 0.089 lb ai/A (7

- day interval) via drip irrigation in melons. Proposed a pplication rates

are as high as 0.35 lb ai/A for a single application via drip chemigation, thus th e application rate used in the residue study with melons is far below what is proposed for

other uses

. In general, the magnitude of residue studies tested at application rates that were higher and/or more frequent tha n th ose tested in the honeybee field effect s studies.

T he magnitude of residues studies did not measure nectar concentrations, but pollen concentrations are generally higher than those detected in the hive studies and likely reflect the higher application rates used in the magnitude of residue studies

. Howeve r, to exceed the LOC of 0.4, an adult worker honeybee foraging for nectar would need to consume a daily dose of 0.464 μg ai/bee, which is six times greater than the maximum dose consumed using the provided residue data.

Many semi

- and full

- field studies were available to evaluate cyantraniliprole’s effects on honeybees. Beginning with bee behavior and mortality, the fiel d studies indicate that cyantraniliprole applications induce tem porary adverse effects (cramping, lethargy, increased grooming behavior , decreased foraging activity) in honey bees. Unlike the foliage residues test, which showed negli gi ble mortality and behavior effects on bees exposed to residues (aged 3 to 72 hours) , the field studies take into consideration the dietary route of exposure as well as the contact route

. Many of the field studies for honeybees reported an increased mortality for up to five day s after the application. Bees exhibited decreased foraging behavior for up to six days after application and it is suggested that cya ntraniliprole has a “repellent” effect on bees. S igns of intoxication were also reported ( e.g ., cramping of bees) . Not surprisingly, applications made during bee flight tended to result in a greater degree of adverse effects than applications made

after bee flight. The combination of mortality, sub

- lethal effects , and repellence (decreased foraging) in cyantraniliprole

- treated plants may affect pollinator services.

Based on the semi

- field stud y data , the effects are expected to be t ransient ( lasting up to
six days).

Although the semi

- field studies indicated transient effects on behavior, foraging activity and mortality, o bservations of brood health and colony strength (up to 28 days) suggested no adverse effects from cyantraniliprole applications . T he results of longer

- term studies must be considered in the context of some uncertainties. Namely, the health of all colonies (controls and treatment) was in decline well before overwintering reductions in colony size should have occurred. However, of th e three studies that followed the hives

### 140 through the overwintering period, most of the data suggest no long

- term effects to honeybees that would differentiate treated from control colonies

.

One semi

- field study monitored the colonies u p to just prior to ov erwinteri ng period (170) days and detected no differences between the controls and treatments. Three studies followed the hives through the ov erwintering period. Two of these demonstrated that hive health and/or brood development was comparable between t he treatment groups

and the controls. In th e third study, the control and one of the t reatment s were sim ilar in their performance, but a second t reatment showed decreased colony strength and a much smaller average number of bees per hive than at the start of the experiment. The second

t reatment involved the application of cyantraniliprole during bee flight whereas in the

first treatment

, applications were made after bee flight. This could be the cause behind the decreased colony size in this study. Howe ver, the other two studies, in which no differences occurred in hive strength after overwintering, also involved treatments where applications of cyantraniliprole were made during bee flight. This remains a point of uncertainty, although overall, the fiel d studies suggest that applications of cyantraniliprole at rates of up to 0.134 lb ai/A d id not adversely affect hive

health /strength relative to controls

.

According to label rates, cyantraniliprole can be sprayed up to 0.175 lb ai/A on brassica leafy v egetables, cucurbits, fruiting vegetables, and leafy vegetables. Foliar ra tes of

0.208 to 0.42 lb ai/A are permitted for flowerbeds and groundcovers, turf/grassy areas, public health insect control, and trees and ornamental plants. These rates were not

a ddressed in the honeybee field trials and the effects to hive health from these higher

rates are uncertain.

I n one of the field studies, v arroa mites infested all of the colonies. The hives exposed to cyantraniliprole

- treated crops had higher mites loads than the control hives. This could

indicate that cyantraniliprole may increase the susceptibility of hives to other

environmental stressors ; however there is uncertainty in this premise because the study was not designed to specific ally test the effects of varroa mites on hives.

Another route of exposure is through the dust associated with planting cyantraniliprole

treated seeds or harvesting cyantraniliprole

- treated crops. Bees may be exposed to dust while in flight (contact) or when visiting dust

- laden flowers (contact or dieta ry). Dust generated from the abrasion of treated seed coats during planting has been lin ked to bee mortality (Pistorius et al . 2009; Forster et al. 2009) and is the subject of ongoing research (Tapparo et al. 2012; Krupke et al. 2012).

Finally, there is further uncertainty about the typical end

- use products that contain both cyantraniliprole and thiamethoxam. Individual toxicity data for each of these chemicals indicate that they are both highly toxic to bees. The contact and dietary acute toxicity

data from a laboratory study indicate that the co

- formulated product is more toxic than cyantraniliprole alone, but less toxic than thiamethoxam alone. No field studies were available for this product and its short and long

- term effects on pollinator services and honeybee colony health are unknown.

### 141 Data were available for a number of other terrestrial invertebrates as well. They suggested that sensitivity to cyantraniliprole varies, depending on the organisms. Parasitoid wasps were the most sensitive, while collembola, beetles, lacewings, predatory mites, and spiders were not as sensitive. Earthworms also appeared to be generally unaffected by the cyantraniliprole application rates that were tested. As with the honeybee studies, these rates did not approac h the single maximum of 0.69 lb ai/A.

Overall, the combination of laboratory and field studies suggest s that risk concerns are possible for cyantraniliprole

. The Tier II risk quotient analysis indicated that the acute oral exposure route is likely not a risk concern; however, risk concerns for contact toxicity can not be eliminated, based on the Tier I risk quotient analysis. Transient

e ffects were observed up to the maximum application rate tested (0.134 lb ai/A) indicate increased mortality for up to 5 days after application and decreased foraging activity for up to 6 days after application. These effects do not appear to cause long

- lasting damage to the hive as hives that were monitored tended to survive the overwintering period until spring. Cyantra niliprole may increase a hive’s susceptibility to varroa mite infestation, but more evidence is needed to document this premise. The highe st application rates (up

to 0.69 lb ai/A) were not tested, leaving uncertainty as to the effects these rates may have on honeybees. In addition, toxicity data suggest the cyantraniliprole

- thiamethoxam product is more toxic that cyantraniliprole alone, but field studies are not available that assess the effects of this product.

Direct effects to terrestrial invertebrate s may be reduced by limiting the times foliar applications of cyantraniliprole are made to periods whe n pollinators and other invertebrates are not active. There is some uncertainty associated with this action as the

semi

- field studies demonstrated transi ent changes in mortality rates and behavior for applications of cyantraniliprole made after bee flight as well as during bee flight. Sometimes the mortality rates were the same between both groups and sometimes the group receiving the application after be e flight w as lower.

Indirect effects may occur for terrestrial invertebrates that depend on aquatic invertebrates, terrestrial invertebrates, terrestrial monocots, estuarin e/marine fish, and/or

mammals for food , habitat, or environmental services.

b. Plants

Based on the risk quotient analysis, the LOC for risk to listed terrestrial plants was not

exceeded for monocots or dicots. There is some uncertainty rega rding the analysis for

monocots because seedling emergence data were available for only one monocot . Onion was the most sensitive monocot in the vegetative vigor test, but data from this species were found to be unacceptable in the seedling emergence study because of control performance problems. If the seedling emergence NOAEC for onion is ≤0.100, risk quotients would exceed the LOC for some uses. Currently, the most sensitive monocot seedling emergence NOAEC is 0.134 lb ai/A. Risk quotients could not be calculated for

non

- listed monocots and dicots because only non

- definitive data were a vailable for these

### 142 endpoints. The listed species risk quotients are based on the NOAEC, which is more

sensitive than the EC 25 

### . Thus, the risk quotients for listed species are expected to be protective of non

- listed species as well. No direct effects are anticipated for terrestrial dicots; however direct effects to listed monocots cannot be precluded because of an

absence of data. I ndirect effects may occur for plants that depend on aquatic

invertebrates , terrestrial invertebrates, terrestrial monocots, estuarine /marine fish, or mammals for seed/propagule dispersal, habitat modification, and environmental services.

4 . Review of Incident Data

Reviews of the Ecological Incident Information System (EIIS, version 2.1) and the Avian Incident Monitoring S ystem (AIMS) were conducted on January 17 , 20 13 . There are no reported incidents for cyantraniliprole in the EIIS or AIMS databases. In addition to the incidents recorded in EIIS and AIMS, additional pesticide incidents are reported to the Agency in aggregated incident reports. Ecological incidents reported in aggregate reports include those categorized as ‘minor fish and wildlife’ (W

- B), ‘minor plant’ (P

- B), and

‘other non

- target’ (ONT) incidents. ‘Other non

- target’ incidents include reports of

adverse effects to insects and other terrestrial invertebrates. As of January 17 , 20 13

, there have been no aggregate cyantraniliprole ecologi cal incidents reported to the Agency. Given that this is a new chemical that has not been registered for use in the

United States or other countries , the existence of ecological incident reports would be unlikely.

5 . Federally Threatened and Endangered (Listed) Species Concerns

a. Action Area

For listed species assessment purposes, the action area is considered to be the area

affected directly or indirectly by the f ederal action and not merely the immediate area involved in the action. At the initial screening

- level, the risk assessment considers broadly described taxonomic groups and conservatively assumes that listed species within those broad groups are located on or adjacent to the treated site and aquatic

or ganisms are assumed to be located in a surface water body adjacent to the treated site. The assessment also assumes that the listed species are located within an assumed area that has the relatively highest potential exposure to the pesticide, and that ex posures are likely to decrease with distance from the treatment area.

If the assumptions associated with the screenin g

- level action area result in risk quotient s that are below the listed species LOCs, a "no effect" determination conclusion is made

with respect to listed species in that taxa, and no further refinement of the action area is necessary. Furthermore , risk quotient s below the listed species LOCs for a given taxonomic group indicate no concern for indirect effects upon listed species that dep end upon the t axonomic group covered by the risk quotient as a resource. However, in situations where the screening assumptions lead to risk quotients in excess of the listed species LOCs for a given taxonomic group, a potential for a "may affect" conclus ion exists and may be associated with direct effects on listed species belonging to that

### 143 taxonomic group or may extend to indirect effects upon listed species that depend upon that taxonomic group as a resource. In such cases, additional information on th e biology of listed species, the locations of these species, and the locations of use sites could be considered to determine the extent to which screening assumptions regarding an action area apply to a particular listed organism. These subsequent refinem ent steps could

consider how this information would affect the action area for a particular listed organism and may potentially include areas of exposure that are downwind and downstream of the pesticide use site.

b. Taxonomic Groups Potentially at Risk

The Level I screening assessment process for listed species uses the generic taxonomic

group

- based process to make inferences on direct effect concerns for listed species. The first iteration of reporting the results of the Le vel I screening is a listing of pesticide use

sites a nd taxonomic groups for which risk quotient calculations reveal values that meet or exceed the listed species LOCs (for more information see, USEPA 2004).

(1). Discussion of Risk Quotients

The results of this screening

- level risk assessment indicate that the proposed cyantraniliprole uses have the potential for direct adverse effects to listed and non

- list ed mammals (chronic), freshwater invertebr ates (acute ), terrestrial i nvertebrates, estuarine/marine invertebrates (acute) and benthic invertebrates ( acute and chronic)

. Direct effects to listed terrestrial monocots also cannot be precluded because of an

absence of data. This indicates a potential risk for direct adverse e ffects to federall y

listed aquatic invertebrates , terrestrial invertebrates, terrestrial monocots, and mammals and indirect adverse effects to any listed species that rely on these taxa as resources critical to their life cycle.

( 2). Probit Dose Response Relationship

T he probit slope response relationship can be used to calculate the chance of an individual event corresponding to the listed species acute risk quotients . The analysis

uses the Environmen tal Fate and Effects Division spreadsheet IECv1.1.xls. Slopes were not available for the acute toxicity studies , thus, a default slope assumption of 4.5 was

used

. Only freshwater, estuarine/marine , and benthic invertebrates were analyzed

because these ta xonomic groups yielded acute risk quotients above the LOC (0.05). The

results of the probit

- dose analyses are listed below in Table 50

.

Table 50

. Summary of Individual Effect Probabilities for Cyantraniliprole Exposure at Scenarios that Produce RQs that Exceed the LOC

Taxa RQ Range Probit Slope Chance of Effect (1 in...) (range)

Freshwater Invertebrates EC 50 = 20.4 μg ai/L 0.05

- 0.39 1 4.5 (default slope) 30 to 418,000,000

E stuarine /M arine Invertebrate E C 50 = 520 μg

ai/L 0.05

- 0.073 4.5 (d efault slope) 6,380,000 to 418,000,000

Benthic invertebrates EC 50 = 719 μg ai/L 0.05

- 0.0 51 4.5 (default slope) 332,000,000 to

### 144 418,000,000

1 Based on RQ generated in Risk Description section using the parent

- only approach.



### (3). Spray Drift Analysis

T o determine terrestrial habitats of concern from cyantraniliprole exposures through spray drift, it is necessary to estimate the distance that spray applications can drift from the treated area and still be present at concentrations that exceed levels of c oncern

. A pplications of cyantraniliprole granular formulations , seed treatments, soil injection/drench, and drip chemigation are expected to result in negligible drift. For spray applications , a quantitative analysis of spray drift distances was complete d using AgDRIFT (v. 2.1

. 1) using default inputs for ground applications ( i.e ., high boom, ASAE droplet size distribution = Very Fine to Fine, 90 th 

### data percentile) and aerial applications ( i.e ., ASAE Very Fine to Fine ). Only agricultural uses applied with ground boom or aerial spray equipment are modeled. Only organisms/scenarios that exceeded the acute

risk to listed species LOCs are modeled. In addition to technical

- grade cyantraniliprole,

the typical end

- use produc t s with thiamethoxam are also modeled because they presented more sensitive toxicity values than their technical

- grade counterparts. Further, definitive toxicity values were only available for typical end

- use products for honeybees, thus only

th ese are mo deled here ( Tables 51

- 53 ).

Table 51

. Terrestrial Insect Buffers for Cyantraniliprole Calculated with AgDRIFT

Use Single application

r ate (lb

ai/A) Fraction of Applied Buffer Distance (ft)

TEP (cyantraniliprole only) TEP (cyantraniliprole

and thiamethoxam) TEP (cyantraniliprole only) TEP (cyantraniliprole

and thiamethoxam)

Diet Contact Diet Contact Diet Contact Diet Contact

Brassic a leafy vegetables, leafy vegetables (aerial) 0.175 0.002 0.105 0.0001 0.011 >1000 285 >1000 >1000

Brassica leafy vegetables, leafy vegetables (ground) 0.175 0.002 0.105 0.0001 0.011 797 26 >1000 217

Cucurbits, fruiting vegetables (aerial) 0.175 0.002 0.052 0.0001 0.005 >1000 699 >1000 >1000

Cucurbits, fruiting vegetables (ground) 0.175 0.002 0.052 0.0001 0.005 797 49 >1000 >1000

Brassica leafy vegetables, bushberries, leafy vegetables (except brassica), corm and tuberous vegetables, bulb vegetables, (aerial) 0.133 0.002 0.167 0.0001 0.005 >1000 161 >1000 >1000

Brassica leafy vegetables, bushberries, leafy vegetables (except brassica), corm and tuberous vegetables, bulb vegetables (ground) 0.133 0.002 0.167 0.0001 0.005 797 16 >1000 >1000

Citrus, cotton, oil seeds, pome fruit, stone fruit, tree nuts (aerial) 0.133 0.002 0.138 N/A N/A >1000 207 N/A N/A

Citrus, cotton, oil seeds, pome fruit, stone fruit, tree nuts (ground) 0.133 0.002 0.138 N/A N/A 797 20 N/A N/A

Flowerbeds and groundcovers 0.208 0.002 0.089 N/A N/A 797 30 N/A N/A

### 145 Use Single application

r ate (lb

ai/A) Fraction of Applied Buffer Distance (ft)

TEP (cyantraniliprole only) TEP (cyantraniliprole

and thiamethoxam) TEP (cyantraniliprole only) TEP (cyantraniliprole

and thiamethoxam)

Diet Contact Diet Contact Diet Contact Diet Contact

(ground) Ornamentals treated by

commercial and consumer applicators (ground) 0.13 0.003 0.143 0.0001 0.015 607 20 >1000 164

Ornamental plants, fruit and nut trees (non

- bearing) and forest seedlings grown in greenhouses, lath and shade houses, containers, field nurseries and interiorscapes, turf, golf courses, residential lawns, commercial grounds, parks, playgrounds, athletic

f ields, sod farms, grassy, weedy, mulched, or bare soil

areas in and around greenhouses, nurseries, interior plantscapes, lath and

shade houses , under trees and shrubs that are being grown

in

- ground (ground) 0.26 0.002 0.070 0.0001 0.007 797 37 >1000 322

Ornamental plants (exterior landscapes and interior plantscapes), trees (including

non

- bearing fruit and nut trees), shrubs, evergreens, bedding plants, flowering plants, flowers, foliage plants, groundcovers, vines, interior plantscape plants, vegetable

t ransplants (fruiting, leafy, tuberous, corm), public health insect control (ground) 0.42 0.002 0.043 N/A N/A 797 59 N/A N/A



### N/A = not calculated because acute RQ did not exceed LOC

Table 52

. Freshwater Invertebrate Buffers for Cyantraniliprole Calculated with AgDRIFT

Use Single application Rate (lb ai/A) Freshwater Invertebrate Buffer Distance (ft) cyantraniliprole

- only Freshwater Invertebrate Buffer Distance (ft) cyantraniliprole and

thiame thoxam

Initial Average Concentration (ng ai/L) Initial Average Concentration (ng ai/L)

Acute (10200) Acute

restricted

(2040) Acute

listed (1020) Acute (2800) Acute

restricted

(560) Acute

listed (280)
Brassica leafy vegetable, cucurbits, fruiting vegetables, leafy vegetables, (aerial) 0.175 0 26 197 0 518 >1000

Brassica leafy vegetable, cucurbits, fruiting vegetables, leafy vegetables, (ground) 0.175 0 0 0 0 3 23

### 146 Use Single application Rate (lb ai/A) Freshwater Invertebrate Buffer Distance (ft) cyantraniliprole

- only Freshwater Invertebrate Buffer Distance (ft) cyantraniliprole and

thiame thoxam

Initial Average Concentration (ng ai/L) Initial Average Concentration (ng ai/L)

Acute (10200) Acute

restricted

(2040) Acute

listed (1020) Acute (2800) Acute

restricted

(560) Acute

listed (280)
Brassica leafy vegetables, bushberries, citrus, cotton, leafy vegetables (except brassica), oil seeds, pome fruit, corm and tuberous vegetables, stone fruit, tree nuts, bulb vegetables, (aerial) 0.133 0 0 115 0 335 >1000

Brassica leafy vegetables, bushberries, citrus, cotton, leafy vegetables (except brassica), oil seeds, pome fruit, corm and tuberous vegetables, stone fruit, tree nuts, bulb vegetables, (ground) 0.133 0 0 0 0 0 13

Flowerbeds and ground covers (ground) 0.208 0 0 0 0 7 33

Ornamentals treated by

commercial and consumer applicators, turf, golf courses,

residential lawns, commercial grounds, parks, playgrounds, athletic fields, sod farms (ground) 0.13 0 0 0 0 0 10

Ornamental plants (exterior landscapes and interior plantscapes), trees (including

non

- bearing fruit and nut trees), shrubs, evergreens, bedding plants, flowering plants, flowers, foliage plants, groundcovers, vines, interior plantscape plants, vegetable transplants (fruiting, leafy, tuberous, corm), public health insect control (ground) 0.42 0 0 7 0 33 115

Grassy, weedy, mulched, or bare

soil areas in and around greenhouses, nurseries, interior plantscapes, lath and shade

houses , under trees and shrubs that are being grown in

- ground (ground) 0.233 0 0 0 0 7 43

Ornamental plants, fruit and nut

trees (non

- bearing) and forest seedlings grown in greenhouses, lath and shade houses, containers, field nurseries and interiorscapes, (ground) 0.26 0 0 0 0 10 52

TGAI

– technical grade active ingredient

TEP

– typical end

- use product



### Table 53

. Estuarine/Marine Invertebrate Buffers for Cyantraniliprole Calculated with AgDRIFT

### 147 Use Single application Rate (lb ai/A) Estuarine/Marine Invertebrate Buffer Distance (ft) Initial Average Concentration (ng ai/L)

Acute (260000) Acute

restricted (52000) Acute

listed (26000)

Cotton (aerial) 0.133 0 0 0 Cotton (ground) 0.133 0 0 0 Cucurbits, fruiting vegetables, (aerial) 0.175 0 0 0

Cucurbits (ground) 0.175 0 0 0



### For terrestrial insects, the AgDRIFT analysis indicates that buffers of 797 to > 1000 ft would be necessary to lower risk quotients below the LOC, when applying typical end

use cyantraniliprole

- only products. The cyantraniliprole

- thiamethoxam mixture would require buffer in excess of 1000 ft for all uses

. For freshwater invertebrate exposures, acute listed species buffers range from 0 to 197 ft (TGAI) and 0 to >1000 ft (TEP). The analysis clearly shows that, again, the cyantraniliprole

- thiamethoxam mixtur e will require larger buffers than cyantraniliprole

- only products. The limited number of uses that

exceeded the LOC for estuarine/marine invertebrates indicated that buffers are not needed to protect these organisms from spray drift.

(4). Indirect Effec ts Analysis

The Agency acknowledges that pesticides have the potential to exert indirect effects upon listed organisms by, for example, perturbing forage or prey availability, altering the extent of nesting habitat, and creating gaps in the food chain. In conducting a screen for indirect effects, direct effect LOCs for each taxonomic group are used to make inferences concerning the potential for indirect effects upon listed species that rely upon non

- listed organisms in these taxonom ic groups as resources critical to their life cycle.

The results of this screening

- level risk assessment indicate that the proposed uses for cyantraniliprole have the potential for direct adverse effects to listed and non

- listed mammals from chronic exp osure, listed freshwater invertebrates from acute exposures, listed estuarine/marine invertebrates from acute exposures, listed terrestrial insects from

acute exposures, listed benthic invertebrates from acute exposures, and listed and non

listed benthic i nvertebrates from chronic exposures. Given the absence of data, direct effects cannot be precluded for terrestrial monocots and estuarine/marine fish

. This indicates a direct risk to these groups as well as i ndirect effects to all species that depend

on aquatic invertebrates , terrestrial invertebrates, terrestrial monocots, estuarine/marine fish, and/or mammals for food, habitat, or other environmental resources. T herefore, at this time, no federally

- listed taxa can be excluded from the potential for dir ect and/or indirect effects from the proposed uses of cyantraniliprole ( Table 54 ) . Species

- specific concerns for indirect effects to listed organisms will require a determination of the

coincidence of cyantraniliprole use with locations of listed species and the biologically based resources upon which they depend.

### 148

### 149 Table 54

. Listed Species Risks Associated with Potential Direct or Indirect Effects

from the Proposed Applications of Cyantraniliprole

L isted Taxon D irect Effects I ndirect Effects

Terrestrial and semi

- aquatic plants

- monocots Yes 2 Yes 1

Terrestrial and semi

- aquatic plants

- dicots No Yes 1

Terrestrial in vertebrates Yes Yes 1

Birds No Yes 1

Terrestrial

- phase amphibians No Yes 1

Reptiles No Yes 1

Mammals Yes (chronic ) Yes 1

Aquatic plants No Yes 1

Freshwater fish No Yes 1

Aquatic

- phase amphibians No Yes 1

Freshwater invertebrates Yes ( acute ) Yes 1

Benthic invertebrates Yes ( acute and chronic) Yes 1

Marine/estuarine fish Yes (chronic) 2 Yes 1

Marine/estuarine invertebrates Yes (acute ) Yes 1

1 The potential for adverse effects to those species that rely on plant and/or animal species (specifically aquatic invertebrates, or mammals) cannot be precluded. Indirect effects may include general habitat modification, host plant loss, and food supply disruption.

2 Risk assumed based on an absence of data.



### (5 ). Critical Habitat

In the evaluation of pesticide effects on designated critical habitat, consideration is given

to the physical and biological features (constituent elements) of a critical habitat identified by the U. S. Fish and Wildlife and National Marine Fisheries Services (the Services) as essential to the conservation of a listed species and which may require

spe cial management considerations or pro tection. The evaluation of effe cts for a screening

- level pesticide risk assessment focuses on the biological features that are

### 150 constituent elements and is accomplished using the screening

- level taxonomic analysis (RQs) and levels of concern (LOCs) that are used to evaluate direct and indirect effects to listed organisms.

The screening

- level risk assessment has identified potential concerns for indirect effects on listed species for those organisms dependent upon some a nimals (mammals

, aquatic

invertebrates

, terrestrial monocots, estuarine/marine fish, and terrestrial invertebrates ). In light of the potential for indirect effects, the next step for EPA and the Services is to identify which listed species and their designated critical habitat(s), if applicable, are potentially implicated. Analytically, the identification of such species and their critical habitat can occur by determining whether the action area overlaps designated critical habitat or the occupied ra nge of any listed species. If so, EPA would examine whethe r the pesticide's potential effe cts on non

- listed species would affect the listed species indirectly, or directly affect a constituent element of the critical habitats. At present, the

information reviewed by EPA does not permit use of this analytical approach to make a

definitive identification of s pecies that are potentially affe cted indirectly or designated critical habitats that are potentially affected directly by the proposed uses of

cyantran iliprole

.

This screening

- level risk assessment for critical habitats provides a listing of potential biological features that, if they are constituent elements of one or more critical habitats, would be of potential concern. These correspond to the taxa identified above ( i.e.

, mammals , terrestrial monocots, estuarine/marine fish, terrestrial invertebrates, and aquatic invertebrates) as being of potential concern for adverse effects. This should serve as an initial step in problem formulation for further assessment of designated critical habitat impacts outlined above, should additional work be necessary.

(6 ). Co

- occurrence Analysis

The goal of the analysis for co

- location is to determine whether sites of pesticide use are geograph ically associated with known locations of listed species. At the screening level, this analysis is accomplished using the LOCATES (version 2.2.4 ) database. The database uses location information for listed species at the county level and compares it

to a gr icultural census data (from 2007 ) for crop production at the same county level of resolution. The product is a listing of federally

- listed species that are located within counties known to produce the crops upon which the pesticide will be used

. The current analysis is b ased on the following proposed crops: almonds, apples, apricots, artichokes, beets, bittermelon, blueberries, broccoli, Brussels sprouts, Chinese cabbage, head cabbage, mustard cabbage, cantaloupe, canola, cassava, cauliflower, c elery, cherries, chestnut, Christmas trees, citron, citrus, collards, cotton, crambe, cucumbers and pickles, currants, eggplant, endive and escarole, garlic, grapefruit, hazelnuts, honeydew melon, jojoba harvest, kale, kumquats, lemons, lemons and limes, l ettuce, limes, macadamia nuts, muskmelons and pepinos, mustard greens, mustard seed, nectarines, nuts, okra, onions, oranges, orchards, peaches, pears, pecans, peppers, persimmons, pistachios, plums and prunes, pluots, potatoes, pumpkins, rapeseed, rhubarb , sesame, sod harvested, spinach, squash, sunflower seed, sweet potatoes, tangelos, tangerines, tomatoes, walnuts,

### 151 watermelons, woodlands, and yams

. For potential direct effects, only listed mammals, aquatic invertebrates, and terrestrial insects will be considered, since they were the only

taxa for which direct risks were identified . For indirect effects, all other taxa will be considered since there is a potential for indirect effects to taxa that might rely on aquatic

invertebrates , terrestrial inverte brates, terrestrial monocots, estuarine/marine fish, and/or

mammals for some stage of their life

- cycle.

LO CATES identified a total of 1377 listed species that overlap at the county

- level with

areas where cyantraniliprole is proposed to be used (see Appendix I for a complete species list). This preliminary analysis indicates that there is a potential for cyantraniliprole use to overlap with listed species and that a more refined assessment is

warranted. The more refined assessment should involve cle ar delineation of the action area associated with proposed uses of cyantraniliprole and best available information on the temporal and spatial co

- location of listed species with respect to the action area

. This analysis has not been conducted for this ass essment.

V. UNCERTAINTIES

There were a number of ecological data gaps identified during the course of the

assessment.

Estuarine/Marine Fish Early Life

- Stage (850.1400): The current early life

- stage study for estuarine/marine fish presents a non

- definiti ve NOAEC (less than value). Without a definitive lower bound on cyantraniliprole’s toxicity, chronic risk concerns for estuarine/marine fish cannot be precluded.

Field Testing for Pollinators (850.3040): Multiple semi

- field studies are available for

cyan traniliprole; however, these tests were conducted up to 0.134 lb ai/A, whereas the maximum application rate fo r some uses is up to 0.69 lb ai/A. There is uncertainty regarding the effects to honeybee hive health and pollinator services at application rate s above 0.134 lb ai/A.

Larval Honeybee Toxicity Test (Non

- Guideline Study): Given that cyantraniliprole is highly toxic to adult honeybees, a larval toxicity test would provide information on the level of toxicity to larvae. Food type and consumption rates differ from adults and larvae

could be more or less sensitive to the tox icity of cyantraniliprole and/or experience different exposure routes than adults. In the absence of this study, information from the

semi

- field studies was used to extrapolate the effects of cyantraniliprole on larvae.

Seedling Emergence Test (850.4100): Only a partial set of acceptable data were available for this test (corn, cucumber, oilseed rape, soybean, and sugar beet). Onion, the most sensitive monocot in the vegetative vigor test, was not tested. In the absence of a complete set of data, the re sults of the partial set were used, but there is uncertainty that

the most sensitive monocot was tested.

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- 95/002F. April

1998. http://cfpub.epa.gov/ncea/cfm/recordisplay.cfm?deid=30759

USEPA. 2004. Overview of the Ecological Risk Assessment Process in the Office of Pesticide Programs. U.S. Environmental Protection Agency, Office of Prevention, Pesticides and Toxic Substances, Office of Pesticide Programs, Washington DC. January 23, 2004.

USEPA. 2005. PRZM

- 3, A Model for Predicting Pesticide and Nitrogen Fate in the Crop Root and Unsaturated Soil Zones: Users Manual for Release 3.0. May 2005.

USEPA, 2009a. Guidance for Selecting Input Parameters in Modeling the Environmental

Fate and Transport of Pesticides. Version 2.1 October 22, 2009. http://www.epa.gov/oppefed1/models/water/input_guidance2_28_02.htm . U.S. Environmental Protection Agency, Office of Pesticide Programs, Environmental Fate and Effects Division. Arlington, VA.

USEPA, 2009b. DRAFT Guidance for Modeling Pesticides Total Toxic Residues (TTR) May 20, 2009. U.S. Environmental Protection Agency, Office of Pesticide Programs,

Environme ntal Fate and Effects Division. Arlington, VA.

USEPA, 2009c. DRAFT NAFTA Guidance for Evaluating and Calculating Degradation Kinetics in Environmental Media, U.S. Environmental Protection Agency, Office of Pesticide Programs, Environmental Fate and Effe cts Division. Arlington, VA.

### 1 54 USEPA. 2011a. Per

- acre application rates for ornamental trees in urban forests, seed

treatment and container

- grown ornamental uses of paclobutrazol. Memo to

Environmental Fate and Effects Division and Pesticide Re

- Evaluation Division, Office of
Pesticide Programs, United States Environmental Protection Agency.

USEPA. 2011b. Acres planted per day and seeding rates of crops grown in the United
States. Memo to P. Deschamp, Health Effects Division and D. Spatz, E nvironmental
Fate and Effects Division, Office of Pesticide Programs, United States Environmental
Protection Agency.

USEPA. 2011c. Registration review: problem formulation for the environmental fate, ecological risk, endangered species, and drinking wa ter exposure assessments for thiamethoxam. Environmental Fate and Effects Division, Office of Pesticide Programs, United States Environmental Protection Agency.

USEPA. 2012 a . The drinking water degradates identification memorandum for cyantraniliprole. Environmental Fate and Effects Division, Office of Pesticide Programs, United States Environmental Protection Agency.

USEPA. 2012b. White paper in support of the proposed risk a ssessment process for bees. Environmental Protection Agency, Health Canada, and California Department of Pesticide Regulation

USEPA. 2012c. Cyantraniliprole: Report of the Residues of Concern Knowledgebase Subcommittee (ROCKS). D404411 dated 24 July 2012. U.S. Environmental Protection Agency. Washington, DC.

Submitted Studies

Ecotoxicity Studies:

48119994

– Chapleo, S., and G. Hobbs. The translocation of [14C]DPX

- HGW86 into pollen and stamens of sunflower, canola, tomatoes and zucchini . Project number:

DuPont/17705.

48120013

- Chapleo, S., and G. Hobbs. The translocation of [14C]DPX

- HGW86 into pollen and

stamens of Phacelia tanacetifolia . DuPont/26578.

48120090

- Kling, A. ( 2005 ); DPX

- HGW86 technical: Acute oral and contact toxicity to the honeybee, Apis mellifera L. Project number: DuPont/17000, 20051145/01/BLEU, 15854. Unpublished study prepared by GAB Biotechnologie Gmbh.

48120091

- Samel, A. ( 2006 ); DPX

- HGW86 technical: 21

- day chronic static

- renewal toxicity

test to Daphnia magna. Project number: DuPont/17002/OCR, 15854, 254. Unpublished study prepared by E.I. du Pont de Nemours and Company.

48120092

- Krueger, H.O., Thomas, S., Kendall, T.Z. ( 2 007b ); 14 

### C

- DPX

- HGW86: A prolonged sediment toxicity test with Chironomus riparius using spiked sediment. Project number: DuPont/17463/OCR, 112A/195, 15985. Unpublished study prepared by Wildlife International, Ltd.

### 155 48120093

- Krueger, H.O., Thomas, S., Kendall, T.Z. ( 2007a ); 14 

### C

- DPX

- HGW86: A prolonged sediment toxicity test with Chironomus riparius using spiked water. Project number: DuPont/17464/OCR, 112A/196, 15985. Unpublished study prepared by Wildlife International, Ltd.

48120094

- Samel, A. ( 2 006b ); DPX

- HGW86 technical: Static, acute, 48

- hour toxicity test to Chironomus riparius . Project number: DuPont/17465/OCR, 15854, 1381. Unpublished study prepared by E.I. du Pont de Nemours and Company.

48120095

- Blankinship, A.S., Kendall, T.Z., Krue ger, H.O. ( 2006 ); DPX

- HGW86: A 96

- hour shell deposition test with the eastern oyster ( Crassostrea virginica ). Project number: DuPont/17466/OCR, 112A/198, 15978. Unpublished study prepared by Wildlife International, Ltd.

48120096

- Blankinship, A.S., Ke ndall, T.Z., Krueger, H.O. ( 2006 ); DPX

- HGW86 technical: A

96

- hour flow

- through toxicity test with the saltwater mysid ( Americamysis bahia ). Project number: DuPont/17467/OCR, 112A/199A, 15978. Unpublished study prepared by Wildlife International, Ltd.

48120098

- Samel, A. ( 2006b ); DPX

- HGW86 technical: Static, acute, 48

- hour toxicity test to Gammarus pseudolimnaeus

. Project number: DuPont/18433, 16255, 1384. Unpublished study prepared by E.I. du Pont de Nemours and Company.

48120099

- Samel, A. ( 2006 b ); DPX

- HGW86 technical: Static, acute, 48

- hour toxicity test to the mayfly, Centroptilium triangulifer

. Project number: DuPont/18434/OCR, 16255, 1487. Unpublished study prepared by E.I. du Pont de Nemours and Company.

48120101

- Samel, A. ( 2006a ); DPX

- HGW86 technical: Static, acute, 48

- hour toxicity test to the aquatic oligochaete, Lumbriculus variegatus. Project number: DuPont/18435, 16255, 1492. Unpublished study prepared by E.I. du Pont de Nemours and Company.

48120102

- Samel, A. ( 2006a ); DPX

- H GW86 technical: Static, acute, 48

- hour toxicity test to Hyalella azteca. Project number: DuPont/18436, 16255, 1380. Unpublished study prepared by E.I. du Pont de Nemours and Company.

48120103

- Samel, A. ( 2006a ); DPX

- HGW86 technical: Static, acute, 48

- hour toxicity test to Soyedina carolinensis. Project number: DuPont/18889, 16373, 1532. Unpublished study prepared by E.I. du Pont de Nemours and Company.

48120104

- Turner, J.T. ( 2006 ); DPX

- HGW86 technical: Static

- renewal, acute, 96

- hour toxicity test to bluegill sunfish, Lepomis macrochirus. Project number: DuPont/19164, 16497, 226. Unpublished study prepared by E.I. du Pont de Nemours and Company.

48120105

- Gallagher, S.P., Kendall , T.Z., Krueger, H.O. ( 2009b ); Cyantraniliprole technical: A

96

- hour flow

- through acute toxicity test with the sheepshead minnow ( Cyprinodon variegatus ). Project number: DuPont/19165, 112A/256. Unpublished study prepared by

Wildlife International Ltd.

48120106

- Gallagher, S.P., Kendall, T.Z., Krueger, H.O. ( 2009a ); Cyantraniliprole (DPX

HGW86) technical: A 96

- hour flow

- through acute toxicity test with the channel catfish ( Ictalurus punctatus ). Project number: DuPont/19167, 112A/260 17718. Unpublish ed study prepared by Wildlife International Ltd.

48120107

- Porch, J.R., Kendall, T.Z., Krueger, H.O. ( 2009b ); Cyantraniliprole (DPX

- HGW86)

technical: A 72

- hour toxicity test with the freshwater alga ( Pseudokirchneriella subcapitata ). Project number: Du Pont/19190, 112A/247, 17718. Unpublished study prepared by Wildlife International Ltd.

### 156 48120108

- Bouchelle, L.D. ( 2006 ); DPX

- HGW86 technical: Static, acute, 96

- hour toxicity test with rainbow trout, Oncorhynchus mykiss. Project number: DuPont/19191, 1 6497, 228. Unpublished study prepared by E.I. DuPont de Nemours and Company.

48120109

- Samel, A. ( 2007 ); DPX

- HGW86 technical: Early life

- stage toxicity to rainbow trout, Oncorhynchus mykiss. Project number: DuPont/19192, 16948, 217. Unpublished study prepared by E.I. du Pont de Nemours and Company.

48120110

- Gallagher, S.P., Kendall, T.Z., Krueger, H.O. ( 2009 ); Cyantraniliprole (DPX

HGW86) technical: An early life

- stage toxicity test wit h the sheepshead minnow ( Cyprinodon variegatus ). Project number: DuPont/19193, 112A/275, 17718. Unpublished study prepared by Wildlife International Ltd.

48120113

- Muther

- Paul, J. ( 2007 ); DPX

- HGW86 100 g/L OD: Acute oral and contact toxicity

to the ho ney bee, Apis mellifera L. Project number: DuPont/19229, 20061214/01/BLEU,WR/16513. Unpublished study prepared by Eurofins

– GAB

GmbH.

48120114

- Samel, A. ( 2006 ); DPX

- HGW86 technical: Static, acute, 48

- hour toxicity test with Daphnia magna. Project number: DuPont/20148, 16667, 241. Unpublished study prepared by E.I. du Pont de Nemours and Company.

48120115

- Temple, D.L., Beavers, J.B., Jaber, M. ( 2008a ); DPX

- HGW86 technical: A reproduction study with the mallard. Project number: DuPont/20917, 1 12/586, 16888. Unpublished study prepared by Wildlife International Ltd.

48120116

- Temple, D.L., Beavers, J.B., Jaber, M. ( 2008b ); DPX

- HGW86 technical: A reproduction study with the northern bobwhite. Project number: DuPont/20918, 112/585, 16888. Unpublished study prepared by Wildlife International Ltd.

48120117

- Samel, A. ( 2007 ); DPX

- HGW86 technical: Static, acute, 48

- hour toxicity test with Lepidostoma ontario. Project number: DuPont/20941, 16995, 1531. Unpublished study prepared by E.I. du Pont de Nemours and Company.

48120120

- Yeom, D

- H. ( 2008a ); Static, acute 48

- hour limit test of IN

- J9Z38 to the cladoceran, Daphnia magna. Project number: DuPont/21321, KIT/EG07147, 17606. Unpublished study prepared by Korea Institute of Toxicology.

481 20122

- Lührs, U. ( 2007a ); IN

- J9Z38: Acute toxicity to the earthworm, Eisenia fetida in

artificial soil. Project number: DuPont/21324, 33141021, 17031. Unpublished study prepared by Institut fuer Biologische Analytik und Consulting IBACON.

48120121

- Gopi, R.A. ( 2008a ); Static

- renewal, acute 48 hour toxicity test of IN

- JCZ38 to the cladoceran, Daphnia magna. Project number: DuPont/21322, 08161, 21322. Unpublished study prepared by International Institute of Biotechnology and Toxicology.

48120123

- L ührs, U. ( 2007b ); IN

- JCZ38: Acute toxicity to the earthworm, Eisenia fetida in

artificial soil. Project number: DuPont/21325, 33151021, 17032. Unpublished study prepared by Institut fuer Biologische Analytik und Consulting IBACON.

48120125

- Yeom, D

- H. ( 2008b ); Static, acute 48

- hour limit test of IN

- K5A77 to the cladoceran, Daphnia magna. Project number: DuPont/21392, KIT/EG07149, 17602. Unpublished study prepared by Korea Institute of Toxicology.

48120126

- Lührs, U. ( 2007c ); IN

- K5A77: Acute toxici ty to the earthworm, Eisenia fetida in

artificial soil. Project number: DuPont/21393, 33131021, 17029. Unpublished study prepared by Institut fuer Biologische Analytik und Consulting IBACON.

### 157 48120127

- Hubbard, P.M., Martin, K.H., Beavers, J.B. (2008); DPX

- HGW86 technical: A dietary LC 50 

### study with the mallard. Project number: DuPont/21469, 112/613, 17619. Unpublished study prepared by Wildlife International Ltd.

48120128

- Hubbard, P.M., Martin, K.H., Beavers, J.B. (2008); DPX

- HGW86 technical: A

die tary LC 50 

### study with the northern bobwhite. Project number: DuPont/21470, 112/612, 17619. Unpublished study prepared by Wildlife International Ltd.

48120129

- Adelberger, I. (2008a); Cyantraniliprole (DPX

- HGW86) 100 g/L OD: A laboratory

test to evaluat e the effects on the predatory mite Typhlodromus pyri (Acari, Phytoseiidae). Project number: DuPont/21471, S08/02309/L1/NLTP, 17617. Unpublished study prepared by Eurofins

– GAB GmbH.

48120130

- Adelberger, I. (2008b); Cyantraniliprole (DPX

- HGW86) 100 g/L OD: A laboratory test to study the effects on the parasitoid Aphidius rhopalosiphi (Hymenoptera, Braconidae). Project number: DuPont/21472, S08/02310/L1/NLAP, 17617. Unpublished study prepare d by Eurofins

– GAB GmbH.

48120132

- Porch, J.R., Krueger, H.O. ( 2008 ); DPX

- HGW86 100 g/L OD: Foliage residue toxicity study to the honeybee, Apis mellifera L. Project number: DuPont/21474. Unpublished study prepared by Wildlife International Ltd.

4812 0133

- Yeom, D

- H. ( 2009a ); IN

- J9Z38: 21

- day chronic static

- renewal toxicity test to Daphnia magna. Project number: DuPont/21479, KIT/EG07148, 17606. Unpublished study prepared by Korea Institute of Toxicology.

48120135

- Mamet, O. ( 2008a ); DPX

- HGW86 10 0 g/L OD: A semi field study to evaluate effects on the honey bee ( Apis mellifera mellifera ; Hymenoptera, Apidae) on wheat treated with artificial honeydew in France 2008. Project number: DuPont/21705, 127/2008. Unpublished study prepared by Testapi.

4 8120136

- Mamet, O. ( 2008b ); DPX

- HGW86 100 G/L OD: A semi field study to evaluate effects on the honey bee ( Apis mellifera ; Hymenoptera, Apidae) on phacelia in France

2008. Project number: DuPont/21706, 128/2008. Unpublished study prepared by Testapi.

48120137

- Jeyalakshmi, T. ( 2008 ); DPX

- HGW86 200 g/L SC: Acute oral and contact toxicity to the honeybee, Apis mellifera L. Project number: DuPont/21860, 08029, 17616. Unpublished study prepared by International Institute of Biotechnology and Toxicolog y. 48120138

- Kleinhenz, M. ( 2009 ); DPX

- HGW86 100 g/L OD: A semi

- field study to evaluate effects on the honey bee ( Apis mellifera carnica ; Hymenoptera, Apidae) in Phacelia tanacetifolia in Germany 2008. Project number: DuPont/21984, S08/01287. Unpublis hed study prepared by Eurofins

– GAB GmbH.

48120141

- Dutt, M.S. ( 2008a ); IN

- K5A78: Acute toxicity to the earthworm, Eisenia fetida , in

artificial soil. Project number: DuPont/24236, 07369, 17611. Unpublished study prepared by International Institute o f Biotechnology and Toxicology.

48120142

- Gopi, R.A. ( 2008c ); Static

- renewal, acute 48 hour limit test of IN

- K5A78 to the cladoceran, Daphnia magna. Project number: DuPont/24237, 07368, 17611. Unpublished study prepared by International Institute of Biotechnology and Toxicology.

48120144

- Shanmugasundaram, R. ( 2008b ); IN

- JSE76: Acute toxicity to the earthworm, Eisenia fetida in artificial soil. Project number: DuPont/24239, 07367, 17562. Unpublished study prepared by International Institute of Biotechnology and Toxicology.

### 158 48120145

- Chittibabu, R.A. ( 2008a ); Static, acute 48

- hour toxicity of IN

- JSE76 to the cladoceran, Daphnia magna . Project number: DuPont/24240, 07366, 17562. Unpublished study prepared by International Institute of Biotechnology and Toxicology.

48120149

- Shanmugasundaram, R. ( 2008a ); IN

- PLT97: Acute toxicity to the earthworm, Eisenia fetida in artificial soil. Project nu mber: DuPont/24244, 07365, 17599. Unpublished study prepared by International Institute of Biotechnology and Toxicology.

48120150

- Dutt, M.S. ( 2008b ); IN

- K5A79: Acute toxicity to the earthworm, Eisenia fetida in

artificial soil. Project number: DuPon t/24245, 07371, 17614. Unpublished study prepared by International Institute of Biotechnology and Toxicology.

48120151

- Chittibabu, R.A. ( 2008b ); Static

- renewal, acute 48 hour toxicity test of IN

- PLT97 to the cladoceran, Daphnia magna. Project number: DuPont/24246, 07364, 17599. Unpublished study prepared by International Institute of Biotechnology and Toxicology.

48120152

- Gopi, R.A. ( 2008b ); Static, acute 48 hour toxicity test of IN

- K5A79 to the cladoceran, Daphnia magna. Project number: DuPont/24247, 07370, 17614. Unpublished study prepared by International Institute of Biotechnology and Toxicology.

48120153

- Hubbard, P.M., Beavers, J.B. (2008); DPX

- HGW86 technical: An acute oral toxicity study with the northern bobwhite. Pro ject number: DuPont/24248, 112/614, 17169. Unpublished study prepared by Wildlife International Ltd.

48120154

- Adelberger, I. (2008b); DPX

- HGW86 200 g/L SC: A laboratory rate response test to evaluate the effects on the predatory mite Typhlodromus pyri (Acari, Phytoseiidae). Project number: DuPont/24249, S08/01342/L1/NLTP, 17616. Unpublished study prepared by Eurofins

– GAB GmbH.

48120155

- Adelberger, I. (2008a); Cyantraniliprole (DPX

- HGW86) 200 g/L SC: A laboratory rate response test to evaluate t he effects on the parasitoid Aphidius rhopalosiphi (Hymenoptera, Braconidae). Project number: DuPont/24250, S08/01341/L1/NLAP, 17616. Unpublished study prepared by Eurofins

– GAB GmbH.

48120157

- Porch, J.R., Kendall, T.Z., Krueger, H.O. ( 2009d ); Cyantr aniliprole (DPX

- HGW86)

technical: A 96

- hour toxicity test with the freshwater, diatom, Navicula pelliculosa. Project number: DuPont/24877, 112a/245, 17718. Unpublished study prepared by

Wildlife International Ltd.

48120158

- Lührs, U. ( 2008 ); DPX

- HGW86 technical: Acute toxicity to the earthworm, Eisenia fetida in artificial soil with 5% peat. DuPont/24880, 42041021, WR/17718. Unpublished study prepared by Institut fuer Biologische Analytik und Consulting IBACON.

48120159

- Moll, M. ( 2009b ); Cyantraniliprole (DPX

- HGW86) 100 g/L OD: An extended laboratory rate response test to study the effects on the green lacewing, Chrysoperla carnea Steph. (Chrysopidae, Neuroptera). Project number: DuPont/25525, 47422047, 17617. Unpublished study prepare d by Institut fuer Biologische Analytik und Consulting

IBACON.

48120160

- Moll, M. ( 2009a ); Cyantraniliprole (DPX

- HGW86) 100 g/L OD: An extended laboratory rate response test to study the effects on the lady bird beetle, Coccinella septempunctata (Coleopt era, Coccinellidae). Project number: DuPont/25526, 47423012, 17617. Unpublished study prepared by Institut fuer Biologische Analytik und Consulting

IBACON.

48120161

- Moll, M. (2009b); Cyantraniliprole (DPX

- HGW86) 100 g/L OD: An extended laboratory rat e response test to study the effects on the parasitoid Aphidius rhopalosiphi (Hymenoptera, Braconidae). Project number: DuPont/25528, 47421002, 17617.

### 159 Unpublished study prepared by Institut fuer Biologische Analytik und Consulting

IBACON.

48120162

- Adelberger, I. (2009); Cyantraniliprole (DPX

- HGW86) 100 g/L SE: A laboratory rate response test to evaluate the effects on the predatory mite Typhlodromus pyri (Acari, Phytoseiidae). Project number: DuPont/25993, S08/02392/NLTP, 17883. Unpublished

stud y prepared by Eurofins

– GAB GmbH.

48120163

- Adelberger, I. (2009); DPX

- HGW86 100 g/L SE: A laboratory rate response test to evaluate the effects on the parasitoid Aphidius rhopalosiphi (Hymenoptera, Braconidae). Project number: DuPont/25994, S08/02393 /L1/NLAP, 17883. Unpublished study prepared by Eurofins

– GAB GmbH.

48120164

- Kling, A. ( 2009a ); Cyantraniliprole (DPX

- HGW86) 100 g/L SE: Acute oral and contact toxicity to the honey bee, Apis mellifera L. Project number: DuPont/25995, S08/02394, 1788 3. Unpublished study prepared by Eurofins.

48120165

- Bruhnke, C. (2010); Cyantraniliprole (DPX

- HGW86) 200 g/L SC: An extended laboratory test to study the effects on the rove beetle Aleochara bilineata (Coleoptera, Staphylinidae). Project number: DuPo nt/26172, IKE12670, 17616. Unpublished study prepared by Dr. U. Noack

- Laboratorien.

48120166

- Bruhnke, C. ( 2010 ); Cyantraniliprole (DPX

- HGW86) 200 g/L SC: Extended laboratory test (dose

- response

- test) on Pardosa spp. (Araneae, Lycosidae). Project

numbe r: DuPont/26173, IPE13423, 17616. Unpublished study prepared by Dr. U.

Noack

- Laboratorien.

48120167

- Lührs, U. ( 2009a ); Cyantraniliprole (DPX

- HGW86) technical: Effects on reproduction and growth of the earthworm, Eisenia fetida , in artificial soil with 5% peat. Project number: DuPont/26883, 42044022, WR/17718. Unpublished study prepared by Institut fuer Biologische Analytik und Consulting IBACON.

48120168

- Moll, M. (2009a); Cyantraniliprole (DPX

- HGW86) 100 g/L SE + Codacide oil: An

extended laborat ory test to evaluate the effects on the parasitoid, Aphidius rhopalosiphi (Hymenoptera, Braconidae). Project number: DuPont/26915, 47431002, 17883. Unpublished study prepared by Institut fuer Biologische Analytik und Consulting

IBACON.

48120169

- Moll, M. ( 2009c ); Cyantraniliprole (DPX

- HGW86) 100 g/L SE: An extended laboratory test to evaluate the effects on the lacewing, Chrysoperla carnea (Neuroptera: Chrysopidae). Project number: DuPont/26927, 47432047, 17883. Unpublished study prepared by Institu t fuer Biologische Analytik und Consulting IBACON.

48120170

- Moll, M. ( 2009d ); Cyantraniliprole (DPX

- HGW86) 100 g/L SE: An extended laboratory test to evaluate the effects on the ladybird beetle, Coccinella septempunctata (Coleoptera, Coccinellidae). Pr oject number: DuPont/26928, 47433012, 17883. Unpublished study prepared by Institut fuer Biologische Analytik und Consulting

IBACON.

48120171

- Hubbard, P.M., Beavers, J.B. ( 2009 ); Cyantraniliprole technical: An acute oral toxicity study with the Zebra finch ( Poephila guttata ). Project number: DuPont/27316, 112/636, 18218. Unpublished study prepared by Wildlife International Ltd.

48120173

- Porch, J.R., Martin, K.H. ( 2009a ); Cyantraniliprole (DPX

- HGW86) 100 g/L OD: A greenhouse study to investigate the effects on vegetative vigor of ten terrestrial plants following foliar exposure. Project number: DuPont/21475, 112/618,17617. Unpublished study prepared by Wildlife International Ltd.

### 160 48120176

- Lührs, U. ( 2009g ); IN

- J9Z38: Effects on reproduction and growth of the earthworm, Eisenia fetida, in artificial soil with 5% peat. Project number: DuPont/27347, 48321022, 18139. Unpublished study prepared by Institut fuer Biologische Analytik und Consulting

IBACON.

48120177

- Lührs, U. ( 2009h ); IN

- PLT97: Effects on reproduction and growth of the earthworm, Eisenia fetida, in artificial soil with 5% peat. Project number: DuPont/27348, 48291022, 17599. Unpublished study prepared by Institute fuer Biologische Analytik und Consulting IBACON.

48120178

- Lüh rs, U. ( 2009f ); IN

- K5A79: Effects on reproduction and growth of the earthworm, Eisenia fetida, in artificial soil with 5% peat. Project number: DuPont/27349, 48341022, 17614. Unpublished study prepared by Institut fuer Biologische Analytik und Consulti ng IBACON.

48120179

- Lührs, U. ( 2009e ); IN

- K5A78: Effects on reproduction and growth of the earthworm, Eisenia fetida, in artificial soil with 5% peat. Project number: DuPont/27350, 48331022, 18142. Unpublished study prepared by Institut fuer Biologis che Analytik und Consulting IBACON.

48120180

- Lührs, U. ( 2009d ); IN

- JCZ38: Effects on reproduction and growth of the earthworm, Eisenia fetida, in artificial soil with 5% peat. Project number: DuPont/27351, 48312022, 18143. Unpublished study prepared by Institut fuer Biologische Analytik und Consulting IBACON.

48120181

- Lührs, U. ( 2009c ); IN

- JSE76: Effects on reproduction and growth of the earthworm, Eisenia fetida, in artificial soil with 5% peat. Project number: DuPont/27352, 48281022,

WR/17562. Unpublished study prepared by Institut fuer Biologische Analytik und Consulting IBACON.

48120182

- Lührs, U. ( 2009b ); IN

- K5A77: Effects on reproduction and growth of the earthworm, Eisenia fetida, in artificial soil with 5% peat. Project number: DuPont/27353, 48301022, WR/18141. Unpublished study prepared by Institut fuer Biologische Analytik und Consulting IBACON.

48120183

- Lührs, U. ( 2009c ); Cyantraniliprole (DPX

- HGW86) technical: Effects on reproduction of the predatory mi te Hypoaspis aculeifer in artificial soil with 5% peat. Project number: DuPont/27445, 49151089, 18218. Unpublished study prepared by Institut fuer Biologische Analytik und Consulting IBACON.

48120184

- Kling, A. ( 2009d ); IN

- HGW87: Acute oral toxicity t o the honey bee, Apis mellifera

L. Project number: DuPont/27448, S09/00176, 18219. Unpublished study prepared by

Eurofins

– GAB GmbH.

48120185

- Kling, A. ( 2009c ); IN

- J9Z38: Acute oral toxicity to the honey bee, Apis mellifera L. Project number: DuPo nt/27449, S09/00177, 17606. Unpublished study prepared by

Eurofins

– GAB GmbH.

48120186

- Porch, J.R., Kendall, T.Z. ( 2010b ); Cyantraniliprole (DPX

- HGW86) 100 g/L OD + Codacide oil: A greenhouse study to investigate the effects on vegetative vigor of ten terresterial plants following foliar exposure. Project number: DuPont/29050, 112/655, 18509. Unpublished study prepared by Wildlife International Ltd.

48120188

- Moll, M. (2009e); Cyantraniliprole (DPX

- HGW86) 100 g/L OD + Codacide oil: An

extended lab oratory test to evaluate the effects on the parasitoid, Aphidius rhopalosiphi (Hymenoptera, Braconidae)

- aged residue test. Project number: DuPont/27694,

### 161 50071003, 18315. Unpublished study prepared by Institut fuer Biologische Analytik und Consulting I BACON.

48120189

- Müther

- Paul, J. (2010a); DPX

- HGW86 100 g/L SE plus Codacide oil: A field study to evaluate effects on predatory mites (acari: phytoseiidae) in apple orchards in Germany, 2009. Project Number: DuPont/27849, S09/02129/01. Unpublished st udy prepared by

Eurofins

– GAB GmbH.

48120190

- Müther

- Paul, J. (2010b); DPX

- HGW86 100 g/L SE plus Codacide oil: A field study to evaluate effects on predatory mites (Acari: Phytoseiidae) in grape vineyards in Italy, 2009. Project number: DuPont/27850, S09/02128/01. Unpublished study prepared by

Eurofins

– GAB GmbH.

48120191

- Höhn, P. ( 2009a ); Cyantraniliprole (DPX

- HGW86) 100 g/L SE plus Codacide oil: An extended laboratory test with field

- aged spray deposits to study the effects on the green lacewin g Chrysoperla carnea steph. (neuroptera, chrysopidae). Project number: DuPont/27851, S09/02357, 18383. Unpublished study prepared by Eurofins

– GAB

GmbH.

48120192

- Höhn, P. ( 2009b ); Cyantraniliprole (DPX

- HGW86) 100 g/L SE plus Codacide oil:

An extended laboratory test with field

- aged spray deposits to study the effects on the ladybird beetle, Coccinella septempunctata L. (Coleoptera, Coccinellidae). Project number: DuPont/27852, S09/02358, 18383. Unpublished study prepared by Eurofins

– GAB G mbH.

48120193

- Höhn, P. (2009); Cyantraniliprole (DPX

- HGW86) 100 g/L SE plus Codacide oil: An extended laboratory test with field

- aged spray deposits to study the effects on the aphid parasitoid, Aphidius rhopalosiphi de Stefani Perez (Hymenoptera, Braconidae). Project number: DuPont/27934, S09/00982/L1/NEAP, 18383. Unpublished study prepared by Eurofins

– GAB GmbH.

48120194

- Lührs, U. ( 2010j ); IN

- K5A77: Effects on the collembola Folsomia candida in

artificial soi l with 5% peat. Project number: DuPont/27975, 48304016, 18141. Unpublished study prepared by Institut fuer Biologische Analytik und Consulting

IBACON.

48120195

- Lührs, U. ( 2010c ); IN

- PLT97: Effects on the collembola Folsomia candida in

artificial soil with 5% peat. Project number: DuPont/27976, 48293016, 17599. Unpublished study prepared by Institut fuer Biologische Analytik und Consulting

IBACON.

48120196

- Lührs, U. ( 2009d ); IN

- PLT97: Effects on reproduction of the predatory mite Hypoaspis aculeifer in artificial soil with 5% peat. Project number: DuPont/27978, 48292089, 17599. Unpublished study prepared by Institut fuer Biologische Analytik und Consulting IBACON.

48120197

- Lührs, U. ( 2010i ); IN

- K5A77: Effects on reproduction of the pre datory mite Hypoaspis aculeifer in artificial soil with 5% peat. Project number: DuPont/27979, 48303089, 18141. Unpublished study prepared by Institut fuer Biologische Analytik und Consulting IBACON.

48120198

- Moll, M. ( 2009e ); Cyantraniliprole (DPX

- HG W86) 100 g/L OD + Codacide oil: An extended laboratory test to evaluate the effects on the lacewing, Chrysoperla carnea (Neuroptera: Chrysopidae)

- aged residue test. Project number: DuPont/28013, 50073048, 18315. Unpublished study prepared by Institu t fuer Biologische Analytik und Consulting IBACON.

### 162 48120199

- Moll, M. ( 2010f ); Cyantraniliprole (DPX

- HGW86) 100 g/L OD + Codacide oil: An extended laboratory test to evaluate the effects on the ladybird beetle, Coccinella septempunctata (coleoptera, cocc inellidae)

- aged residue test. Project number: DuPont/28014, 50074013, 18315. Unpublished study prepared by Institut fuer Biologische Analytik und Consulting IBACON.

48120216

- Lührs, U. (2010); Cyantraniliprole (DPX

- HGW86) 100 g/L OD plus Codacide oi li: Effects on reproduction and growth of the earthworm, Eisenia fetida, in artificial soil with 5% peat. Project number: DuPont/29052, 50076022. Unpublished study prepared by Institut fuer Biologische Analytik und Consulting IBACON.

48120217

- Samel, A. (2006); DPX

- HGW86 100 g/L OD: Static, acute, 48

- hour toxicity test to Daphnia magna. Project number: DuPont/19853. Unpublished study prepared by Dupont Haskell Laboratory.

48120218

- Acute oral toxicity of the preparation to the more sensitiv e of the species identified in tests with the active substance. Project number: DuPont/24484, 112/637. Unpublished study prepared by Wildlife International, Ltd.

48120219

- Dutt, M.S. (2008); DPX

- HGW86 100 G/L OD: Acute toxicity to the earthworm,

Eisen ia fetida in artificial soil. Project number: DuPont/24879, 08115. Unpublished study prepared by International Institute of Biotechnology and Toxicology.

48120220

- Minderhout, T., Kendall, T.Z., Krueger, H.O. (2009); Cyantraniliprole (DPX

HGW86) 100 g/ L OD: A 96

- hour static acute toxicity test with the bluegill ( Lepomis

macrochirus ). Project number: DuPont/26581, 112A/277. Unpublished study prepared by Wildlife International, Ltd.

48120221

- Porch, J.R., Kendall, T.Z., Krueger, H.O. (2009); Cyantran iliprole (DPX

- HGW96) 100 g/L OD: A 72

- hour toxicity test with the freshwater alga, Pseudokirchneriella subcapitata. Project number: DuPont/26715, 112A/272A. Unpublished study prepared by Wildlife International, Ltd.

48120242

- Samel, A. (2010); Cyantra niliprole (DPX

- HGW86) 100 g/L OD plus Codacide, oil: Static, acute, 48

- hour toxicity test with the cladoceran, Daphnia magna. Project number: DuPont/29051, 18509, 241. Unpublished study prepared by Dupont Haskell Laboratory and Critical Path Services, LLC.

48120305

- Hubbard, P.M., Beavers, J.B. (2009); Cyantraniliprole (DPX

- HGW86) 200 g/L SC: An acute oral toxicity study with the northern bobwhite (Colinus virginianus). Project number: DuPont/26580, 112/653. Unpublished study prepared by Wildlife I nternational

Ltd.

48120319

- Samel, A. ( 2011 ); Cyantraniliprole (DPX

- HGW86) 200 g/L SC: Static, acute, 48

- hour toxicity test with the cladoceran, Daphnia magna . Project number: 21478, 09/CPS/001. Unpublished study prepared by Dupont Haskell Laboratory.

48120321

- Minderhout, T., Kendall, T.Z., Krueger, H.O. ( 2009 ); Cyantraniliprole (DPX

HGW86) 200 g/L SC: A 96

- hour static acute toxicity test with the bluegill ( Lepomis

macrochirus ). Project number: DuPont/26582, 112A/276A. Unpublished study prepared b y Wildlife International Ltd.

48120322

- Lührs, U. ( 2008 ); DPX

- HGW86 200 g/L SC: Acute toxicity to the earthworm, Eisenia fetida in artificial soil with 5% peat. Project number: DuPont/26583, 45161021. Unpublished study prepared by Institut fuer Biolog ische Analytik und Consulting

IBACON.

### 163 48120323

- Porch, J.R., Kendall, T.Z., Krueger, H.O. ( 2009 ); Cyantraniliprole (DPX

- HGW86) 200 g/L SC: A 72

- hour toxicity test with the freshwater alga, Pseudokirchneriella subcapitata . Project number: 26716, 112A/27 1. Unpublished study prepared by

Wildlife International Ltd.

48120415

- Samel, A. (2009); Cyantraniliprole (DPX

- HGW86) 100 g/L SE: Static, acute, 48

- hour toxicity test to cladoceran, Daphnia magna . Project number: DuPont/26737/OCR, 17883, 241. Unpublished study prepared by E.I. du Pont de Nemours and Company.

48120416

- Porch, J.R., Kendall, T.Z., Krueger, H.O. (2010); Cyantraniliprole (DPX

- HGW86)

100 g/L SE: A 72

- hour toxicity test with the freshwater alga ( Pseudokirchneriella subcapitata ). P roject number: DuPont/27933/OCR, 112A/310, 18383. Unpublished study prepared by Wildlife International, Ltd.

48122501

- Moll, M. (2009c); Cyantraniliprole (DPX

- HGW86) 100 g/L OD + Codacide oil: A

semi

- field test to evaluate the effects on the parasitoid , Aphidius rhopalosiphi (Hymenoptera, Braconidae). Project number: DuPont/28127, 50072004, 18315. Unpublished study prepared by Institut fuer Biologische Analytik und Consulting

IBACON.

48122504

- Lührs, U. ( 2009f ); IN

- JCZ38: Effects on reproduction of the predatory mite Hypoaspis aculeifer in artificial soil with 5% peat. Project number: DuPont/28198, 48311089, 18143. Unpublished study prepared by Institut fuer Biologische Analytik und Consulting IBACON.

48122505

- Lührs, U. ( 2010a ); IN

- JCZ38: Effects on the collembola Folsomia candida in artificial soil with 5% peat. Project number: DuPont/28199, 48313016, 18143. Unpublished study prepared by Institut fuer Biologische Analytik und Consulting

IBACON.

48122506

- Lührs, U. ( 2009b ); IN

- K5A79: E ffects on reproduction of the predatory mite Hypoaspis aculeifer in artificial soil with 5% peat. Project number: DuPont/28202, 48343089, 17614. Unpublished study prepared by Institut fuer Biologische Analytik und Consulting IBACON.

48122507

- Lührs, U. ( 2010e ); IN

- K5A78: Effects on reproduction of the predatory mite Hypoaspis aculeifer in artificial soil with 5% peat. Project number: DuPont/28203, 48332089, 18142. Unpublished study prepared by Institut fuer Biologische Analytik und Consulting IBACO N.

48122508

- Lührs, U. ( 2010g ); IN

- K5A79: Effects on the collembola Folsomia candida in artificial soil with 5% peat. Project number: DuPont/28204, 48344016, 17614. Unpublished study prepared by Institut fuer Biologische Analytik und Consulting

IBACON

. 48122509

- Lührs, U. ( 2010b ); IN

- K5A78: Effects on the collembola Folsomia candida in artificial soil with 5% peat. Project number: DuPont/28205, 48333016, 18142. Unpublished study prepared by Institut fuer Biologische Analytik und Consulting

IBACON.

48122510

- Lührs, U. ( 2010d ); IN

- JSE76: Effects on reproduction of the predatory mite Hypoaspis aculeifer in artificial soil with 5% peat. Project number: DuPont/28206, 48282089, 17562. Unpublished study prepared by Institut fuer Biologische Analytik und Consulting IBACON.

48122511

- Lührs, U. ( 2009e ); IN

- J9Z38: Effects on reproduction of the predatory mite Hypoaspis aculeifer in artificial soil with 5% peat. Project number: DuPont/28207,

### 164 48322089, 18139. Unpublished study preparedy by Institut fue r Biologische Analytik und Consulting IBACON.

48122512

- Lührs, U. ( 2009a ); IN

- J9Z38: Effects on the collembola Folsomia candida in artificial soil with 5% peat. Project number: DuPont/28208, 48323016, 18139. Unpublished study prepared by Institut fuer Biologische Analytik und Consulting

IBACON.

48122513

- Lührs, U. ( 2010f ); IN

- JSE76: Effects on the collembola Folsomia candida in artificial soil with 5% peat. Project number: DuPont/28209, 48283016, 17562. Unpublished study prepared by Institut fuer Biologische Analytik und Consulting

IBACON.

48122514

- Valentina, J. ( 2009 ); IN

- K5A78: Acute oral toxicity to the honey bee, Apis mellifera

L. Project number: DuPont/28264, 09115, 18388. Unpublished study prepared by

International Institute of Biotechn ology and Toxicology.

48122515

- Samel, A. ( 2009 ); IN

- NXX70: Static, acute, 48

- hour toxicity test with the cladoceran, Daphia magna. Project number: DuPont/28367, 18387, 241. Unpublished study prepared by E.I. du Pont de Nemours and Company.

48122516

- Moll, M. (2010a); Cyantraniliprole (DPX

- HGW86) 100 g/L OD + Codacide oil: An extended laboratory test to evaluate the effects on the parasitoid, Aphidius rhopalosiphi (Hymenoptera, Braconidae). Project number: DuPont/28801, 50075002, 18509. Unpublished study prepared by Institut fuer Biologische Analytik und Consulting

IBACON.

48122517

- Moll, M. (2009d); Cyantraniliprole (DPX

- HGW86) 100 g/L SE + Codacide oil: An extended laboratory test to evaluate the effects on the parasitoid, Aphidius rh opalosiphi (Hymenoptera, Braconidae). Project number: DuPont/28802, 51971002, 18383. Unpublished study prepared by Institut fuer Biologische Analytik und Consulting

IBACON.

48122518

- Kling, A. ( 2009e ); IN

- HGW87: Acute effects to the honey bee, Apis me llifera L. at

low dose levels. Project number: DuPont/29021, S09/02702, 18652. Unpublished study prepared by Eurofins

– GAB GmbH.

48122519

- Moll, M. (2010b); Cyantraniliprole (DPX

- HGW86) 100 g/L OD + Codacide oil: A laboratory test to evaluate the eff ects on the mummies of the parasitoid, Aphidius rhopalosiphi (Hymenoptera, Braconidae). Project number: DuPont/29294, 50077002, 18749. Unpublished study prepared by Institut fuer Biologische Analytik und Consulting

IBACON.

48122520

- Witte, B. ( 2010 ); I N

- QKV54: Effects on reproduction and growth of the earthworm, Eisenia fetida , in artificial soil with 5% peat. Project number: DuPont/29960, 56102022, 18951. Unpublished study prepared by Institut fuer Biologische Analytik und Consulting IBACON.

48122 521

- Fournier, A.E. ( 2010 ); IN

- RNU71: 48

- hour static, acute toxicity with cladoceran Daphnia magna. Project number: DuPont/30091, 97/6519, 19029. Unpublished study prepared by Springborn Smithers Laboratories.

48122522

- Jeyalakshmi, T. ( 2010 ); IN

- RNU71: Effects on reproduction and growth of the earthworm, Eisenia fetida , in artificial soil with 5% peat. Project number: DuPont/30092, 10249, 19029. Unpublished study prepared by International Institute of Biotechnology and Toxicology.

### 165 48122523

- Ferrell, B.D. ( 2010 ); IN

- QKV54: Static, acute, 48

- hour toxicity test with the cladoceran, Daphnia magna. Project number: DuPont/29560, 18951, 241. Unpublished study prepared by E.I. du Pont de Nemours and Company.

48122530

- Lührs, U. ( 2010h ); Cyantran iliprole (DPX

- HGW86) technical: Effects on the

collembola Folsomia candida in artificial soil with 5% peat. Project number: DuPont/27444, 49152016, 18218. Unpublished study prepared by Institut fuer Biologische Analytik und Consulting IBACON.

48122539

- Barth, M. ( 2010 ); Cyantraniliprole (DPX

- HGW86) 100 g/L OD plus Codacide oil: A study to evaluate effects on the honey bee (Apis mellifera L.; Hymenoptera, Apidae)

under semi

- field conditions applied after daily bee

- flight in Phacelia tanacetifolia L. with additional assessments on colony and brood development. Project number: DuPont/27853, 09/10/48/016/B, DuPont/27853/OCR. Unpublished study prepared by Biochem Agrar, Labor fuer Biologische und Chemische.

48122541

- Porch, J.R., Kendall, T.Z., Kruege r, H.O. ( 2009a ); Cyantraniliprole (DPX

- HGW86)

technical: A 96

- hour toxicity test with the freshwater alga (Anabaena flos

- aquae). Project number: DuPont/24876, 112°/244, 17718. Unpublished study prepared by Wildlife International, Ltd.

48122542

- Porch, J.R., Kendall, T.Z., Krueger, H.O. ( 2009c ); Cyantraniliprole (DPX

- HGW86)

technical: A 96

- hour toxicity test with the marine diatom (Skeletonema costatum). Project number: DuPont/24878, 112A/246, 17718. Unpublished study prepared by

Wildlife Internatio nal, Ltd.

48122543

- Porch, J.R., Kendall, T.Z., Krueger, H.O. ( 2009 ); Cyantraniliprole (DPX

- HGW86)

technical: A 7

- day static

- renewal toxicity test with duckweed (Lemna gibba G3). Project number: DuPont/21477, 112A/248, 17718. Unpublished study prepared by Wildlife International, Ltd.

48122545

- Kleinhenz, M. ( 2011c ); DPX

- HGW86 100 g/L OD: A semi

- field study to determine residues in nectar and pollen from foraging honey bees (Apis mellifera carnica; Hymenoptera, Apidae), residues in fresh nectar, pollen and wax from combs and residues in plants and flowers after exposure of the honey bees to treated Phacelia tanacetifolia in Germany in 2008. Project number: DuPont/21481, S08/01316, DuPont/21481/OCR. Unpublished study prepared by Eurofins

– GAB GmbH.

48122546

- Kleinhenz, M. ( 2010b ); DPX

- HGW86 100 g/L OD plus Codacide oil and DPX

HGW86 100 g/L SE plus Codacide oil: A semi

- field study to evaluate effects on the honey bee (Apis mellifera carnica; Hymenoptera, Apidae) in Brassica napus in Southern Germany (Niefern) 2009. Project number: DuPont/21317, S09/00713, DuPont/21317/OCR. Unpublished study prepared by Eurofins

– GAB GmbH.

48122547

- Report: Kleinhenz, M., (2010a); DPX

- HGW86 100 g/L OD plus codacide oil and

DPX

- HGW86 100 g/L SE plus codaci de oil: A semi

- field study to evaluate effects on the honey bee (Apis mellifera carnica; Hymenoptera, Apidae) in Brassica napus in southern Germany (Tübingen) 2009. Project number: DuPont/21318, S09/00714, DuPont/21318/OCR. Unpublished study prepared by Eurofins

– GAB GmbH.

48122548

- Bocksch, S. ( 2011o ); DPX

- HGW86 200SC: A semi

- field study to determine residues in nectar and pollen from foraging honeybees (Apis mellifera; Hymenoptera, Apidae), residues in fresh honey, pollen and wax combs after exposure of the honeybees to drip

- irrigated melon in Spain 2009. Project number: DuPont/27903, S09/00364, DuPont/27903/OCR. Unpublished study prepared by Eurofins

– GAB GmbH.

### 166 48122551

- Kleinhenz, M. ( 2011h ); DPX

- HGW86 100 g/L OD plus Codacide oil: A study to evaluate effects on the honey bee (Apis mellifera carnica) in the field in Brassica napus L. following application after and during bee

- flight in northern Germany (Celle) in 2009. Project number: DuPont/27323, S08/03367, DuPont/27323/OCR. Unpub lished study prepared by Eurofins

– GAB GmbH.

48122552

- Kleinhenz, M. ( 2011d ); DPX

- HGW86 100 g/L OD plus Codacide oil: A study to evaluate effects on the honey bee (Apis mellifera carnica) in the field in Brassica napus L. following application after and during bee

- flight in southern Germany (Tubingen) in

2009. Project number: DuPont/27324, S08/03368, DuPont/27324/OCR. Unpublished study prepared by Eurofins

– GAB GmbH.

48122553

- Kleinhenz, M. ( 2011j ); DPX

- HGW86 100 g/L OD plus Codacide oil: A study t o evaluate effects on the honey bee (Apis mellifera carnica) in the field in Brassica napus L. following application after and during bee

- flight in northern Germany (Stade) in 2009. Project number: DuPont/27326, S09/00344, DuPont/27326/OCR. Unpublished study prepared by Eurofins

– GAB GmbH.

48122557/48688804

- Kleinhenz, M. ( 2011i ); Cyantraniliprole (DPX

- HGW86) 100 g/L OD: A study to evaluate effects on the honey bee ( Apis mellifera carnica ) in the field in Brassica

napus L. following application after and during bee

- flight in southern Germany (Tübingen) in 2010 and 2011. Project number: DuPont/29572/IM, S10/01019, DuPont/29572/IM/OCR. Unpublished study prepared by Eurofins

– GAB GmbH.

48122558/48688805

- Kleinhenz, M. ( 2011k ); Cyantraniliprole (DPX

- HGW86) 100 g/L OD plus Codacide oil: A study to evaluate effects on the honey bee ( Apis mellifera carnica ) in the

field in Brassica napus L. following application after and during bee

- flight in northern France (Alsace) in 201 0 and 2011. Project number: DuPont/29571/IM, S10/01018, DuPont/29571/IM/OCR. Unpublished study prepared by Eurofins

– GAB GmbH.

48122573

- Lührs, U. ( 2010k ); IN

- QKV54: Effects on the collembola Folsomia candida in artificial soil with 5% peat. Project number: DuPont/29990, 56103016, 18951. Unpublished study prepared by Institut fuer Biologische Analytik und Consulting

IBACON.

48122574

- Lührs, U. ( 2010L ); IN

- RNU71: Effects on the Collembola Folsomia candida in artificial soil with 5% peat. Project number: DuPont/30093, 57551016, 19029. Unpublished study prepared by Institut fuer Biologische Analytik und Consulting

IBACON.

48122575

- Porch, J.R., Kendall, T.Z. ( 2010a ); Cyantraniliprole (DPX

- HGW86) 100 g/L OD + Codacide oil: A greenhouse study to investigate the effects on seedling emergence and growth of ten terrestrial plants following soil exposure. Project number: DuPont/29049, 112/654, 18509. Unpublished study prepared by Wildlife International, Ltd.

48208411

- Moll, M. (2010c); Cyantranili prole (DPX

- HGW86) 100 g/L OD + Codacide oil or

without Codacide oil: A semi

- field test to evaluate the effects on the parasitoid, Aphidius rhopalosiphi (Hymenoptera, Braconidae). Project number: DuPont/29957, 55471004, 18978. Unpublished study prepared by Institut fuer Biologische Analytik und Consulting

IBACON.

48208412

- Moll, M. (2010d); Cyantraniliprole (DPX

- HGW86) 100 g/L SE + Codacide oil: A

semi

- field test to evaluate the effects on the parasitoid, Aphidius rhopalosiphi (Hymenoptera, Braconidae) . Project number: DuPont/29958, 55461004, 18979.

### 167 Unpublished study prepared by Institut fuer Biologische Analytik und Consulting

IBACON.

48208413

- Schmitzer, S. (2011); Cyantraniliprole (DPX

- HGW86) 200 g/L SC: An extended laboratory study to evaluate t he effects on the staphylinid beetle, Aleochara bilineata Gyll. Aged residue test. Project number: DuPont/29908, 56121072, 18970. Unpublished study prepared by Institut fuer Biologische Analytik und Consulting

IBACON.

48208414

- Lührs, U. ( 2010o ); IN

- RN U71: Effects on reproduction of the predatory mite Hypoaspis aculeifer in artificial soil with 5% peat. Project number: DuPont/31374, 57553089, 19029. Unpublished study prepared by Institut fuer Biologische analytik und Consulting IBACON.

48208415

- Lü hrs, U. ( 2010n ); IN

- QKV54: Effects on reproduction of the predatory mite Hypoaspis aculeifer in artificial soil with 5% peat. Project number: DuPont/31375, 61481089, 19254. Unpublished study prepared by Institut fuer Biologische Analytik und

Consultin g IBACON.

48208428

- Portillo, H.E., Annan, B., Groya, F., Daly, R., Predoni, D. ( 2010 ); Biological activity of cyantraniliprole and related metabolites on selected insect species under laboratory conditions. Project number: DuPont/30351. Unpublished study prepared by E.I. du Pont de Nemours and Company.

48208451

- Liepold, K. (2010); Cyantraniliprole technical: Soil microarthropod monitoring on plots of a litter bag study. Project number: DuPont/29708, S09/03358, S09/03358/01/NFBO. Unpublished stu dy prepared by Eurofins

– GAB GmbH.

48208453

- Liepold, K. ( 2011 ); Field study to evaluate the effects of cyantraniliprole on collembola in Germany in 2010. Project number: DuPont/29454/IM, S10/01618, DuPont/29454/IM/OCR. Unpublished study prepared by E urofins

– GAB GmbH.

48432413

- Kuhl R, Wydra V (2010), Cyantraniprole WG (A16971B)

- Acute Toxicity to rainbow trout ( Oncorhynchus mykiss ) in a 96

- hour Static Test. Report Number 55824230, Institut für Biologische Analytik und Consulting IBACON GmbH, Arheilger Weg 17, 64380 Rossdorf, Germany.

48432414

- Kuhl H, Wydra V (2010). Cyantraniliprole WG (A16971B)

– Acute Toxicity to Daphnia magna in a Static 48

- hour Immobilisation Test. Report number 55823220, Institut für Biologische Analytik und Consulting IBACON GmbH, Arheilger Weg 17, 64380 Rossdorf, Germany.

48432415

- Kuhl R., Wydra V., (2010), Cyantraniliprole WG (A16971B)

- Toxicity to Pseudokirchneriella subcapitata in an Algal Growth Inhibition Test , Report Number 55822210, Institut für Biologische Analytik und Consulting IBACON GmbH, Arheilger Weg 17, 64380 Rossdorf, Germany.

48432416

- Sekine T, (2010); Cyantraniliprole WG (A16971B)

– Acute Oral and Contact Toxicity on Honey Bees ( Apis mellifera L.). Project number: TK0005927, 55821035. Unpublis hed study prepared by Institut fuer Biologische Analytik und Consulting

IBACON.

48432417

- Stevens J., (2010), Cyantraniliprole WG (A16971B)

– A rate

- response extended laboratory bioassay of the effects of fresh residues on the parasitic wasp Aphidius rhopalosiph (Hymenoptera, Braconidae) . Report Number SYN

- 10

- 12

. Mambo

- Tox Ltd., 2 Venture Road, Chilworth Science Park, Southampton SO16 7NP, United Kingdom.

### 168 48432418

- Fallowfield L, (2010), SYN545377 WG (A16971B)

– A rate

- response extended

labo ratory bioassay of the effects of fresh residues on the predatory mite, Typhlodromus pyri (Acari: Phytoseiidae). Report Number SYN

- 10

- 11. Mambo

- Tox Ltd. 2 Venture Road, Chilworth Science Park, Southampton SO16 7NP, United Kingdom

48432419

- Stevens J. (20 09). Cyantraniliprole WG (A16971B)

– A semi

- field bioassay of the effects of fresh residues on the parasitic wasp Aphidius rhopalosiphi (Hymenoptera, Braconidae). Report Number SYN

- 09

- 22, Mambo

- Tox Ltd., Chilworth Science Park, Southampton SO16 7NP, UK.

48432420

- Friedrich S, (2010), Cyantraniliprole WG, (A16971B)

- Acute toxicity to the earthworm Eisenia fetida, Report Number 10 10 48 024 S. BioChem agrar Labor für biologische und chemische Analytik GmbH Kupferstraße 6 04827 Gerichshain, Germany.

484325 27

- Kuhl R., Wydra V., (2010a), Cyantraniliprole/thiamethoxam WG (A16901B)

- Acute Toxicity to Rainbow Trout ( Oncorhynchus mykiss ) in a 96

- hour Static Limit

- Test, Report Number 55834230, Institut für Biologische Analytik und Consulting IBACON GmbH, Arheil ger Weg 17, 64380 Rossdorf, Germany.

48432528

- Kuhl H, Wydra V (2010c). Cyantraniliprole/thiamethoxam WG (A16901B)

– Acute Toxicity to Daphnia magna in a Static 48

- hour Immobilisation Test. Report number 55833220, Institut für Biologische Analytik und Co nsulting IBACON GmbH, Arheilger Weg 17, 64380 Rossdorf, Germany.

48432529

- Kuhl, R and Wydra, V (2010d), Cyantraniliprole/thiamethoxam WG (A16901B)

- Toxicity to Pseudokirchneriella subcapitata in an Algal Growth Inhibition Test, Report

Number 55832210. Insitut fùr Biologische Analytik und Consulting IBACON GmbH, Arheilger Weg 17, D

- 64380 Rossdorf, Germany.

48432530

- Sekine T, (2010); Cyantraniliprole/thiamethoxam WG (A16901B)

– Acute Oral and Contact Toxicity on Honey Bees ( Apis mellifera L.). Project number: TK0005990, 55831035. Unpublished study prepared by Institut fuer Biologische Analytik und Consulting IBACON.

48432531

- Friedrich S, (2010), Cyantraniliprole/Thiamethoxam WG (A16901B)

- Acute toxicity to the earthworm Eisenia fetida, Report Numbe r 10 10 48 025 S. BioChem agrar Labor für biologische und chemische Analytik GmbH Kupferstraße 6 04827 Gerichshain, Germany.

48663805

- Höhn, P. (2011); Cyantraniliprole (DPX

- HGW86) 100 g/L SE plus Codacide oil: An extended laboratory test with fresh

- drie d and semi

- field

- aged spray deposits to study the effects on the aphid parasitoid, Aphidius rhopalosiphi de Stefani Perez (Hymenoptera, Braconidae). Project number: DuPont/32636.

48688806/48832204

- Bocksch, S. ( 2011 ); Cyantraniliprole (DPX

- HGW86) 100 g/ L OD plus codacide oil: A study to evaluate effects on the honey bee ( Apis mellifera ) in the field in Melon in Spain in 2011. Project number: DuPont/31672/IM, S11/01982, DuPont/31672/IM/OCR. Unpublished study prepared by Eurofins

– GAB GmbH.

Environmental Fate and Transport Studies:

48122593

- Peterson, B.(2007) DPX

- HGW86: Laboratory Study of Vapor Pressure. Project Number: DUPONT 17052. E. I. du Pont de Nemours and Company, Stine

- Haskell Research Center Newark, Delaware 19714

- 0030, USA

4812 0088

- McCorquodale, G.; Burns, L. (2010) [Carbon14]

- IN

- RNU71 a Metabolite of [Carbon14]

- DPX

- HGW86: Batch Equilibrium Adsorption/Desorption in Five Soils.

### 169 Project Number: DUPONT/29989/0CR, 809385.Unpublished study prepared by Charles

River Laboratories. 71 p. 48120087

- McCorquodale, G. (2010) Rate of Degradation [Carbon 14]

- IN

- RNU71 in Five Aerobic Soils. Project Number: DUPONT/29809/0CR, 809343. Unpublished study prepared by Charles River Laboratories. 124 p.

48120086

- Wardrope, L. (201 0) [Carbon 14]

- IN

- QKV54 aMetabolite of [Carbon 14]

- DPX

HGW86: Batch Equalibrium Adsorption/Desorption in Five Soils. Project Number: DUPONT/29558/0CR, 809359. Unpublished study prepared by Charles River Laboratories. 70 p.

48120083

- Wardrope, L. (2010) Rate of Degradati on [Carbon 14]

- IN

- QKV54 in Five Aerobic

Soils. Project Number: DUPONT/29555/0CR, 809317. Unpublished study prepared by Charles River Laboratories. 130 p.

48120082

- Wardrope, L. (201 0) Photodegradation of [Carbon 14]

- DPX

- HGW86 on Moist Soil. Project Numb er: DUPONT/28730/0CR, 809081. Unpublished study prepared by Charles River Laboratories. 138 p.

48120081

- McCorquodale, G. (201 0) Anaerobic Aquatic Metabolism of [Carbon 14]

- DPX

HGW86 in a Water/Sediment System. Project Number: DUPONT/28191/0CR, 809123.

U npublished study prepared by Charles River Laboratories. 104 p.

48120075

- Wardrope, L.; McCorquodale, G. (2007) [Carbon 14]

- IN

- PLT97 (a Metabolite of [Carbon 14]

- DPX

- HGW86): Batch Equilibrium (Adsorption/Desorption) in Five Soils. Project Number: DUPONT/1 9078/0CR, 807393. Unpublished study prepared by Charles River Laboratories. 69 p.

48120074

- Malekani, K. (2008) Rate of Degradation of [Carbon 14]

- IN

- PL T97 in Five Aerobic Soils. Project Number: DUPONT/19077/0CR. Unpublished study prepared by DuPont Crop Protection. 93 p.

48120073

- McCorquodale, G. (2007) [Carbon 14]

- DPX

- HGW86: Batch Equilibrium Adsorption/Desorption) in Five Soils. Project Number: DUPONT/18871/0CR, 807147. Unpublished study prepared by Charles River Laboratories. 66 p.

48120072

- Pils, J. (201 0) Adsorption

- Desorption of [Carbon 14]

- IN

- K5A79 in Five Soils by

Batch Equilibrium. Project Number: DUPONT/18870/0CR. Unpublished study prepared by DuPont Crop Protection. 61 p.

48120071

- Pedersen, C. (201 0) Anaerobic Aquatic Metabolism of (Carb on 14)

- DPX

- HGW86

in a Water

- Sediment System. Project Number: DUPONT/18869/0CR. Unpublished study prepared by DuPont Crop Protection. 99 p.

48120070

- Pedersen, C. (2008) Rate of Degradation of [Carbon 14]

- IN

- K5A79 in Five Aerobic Soils. Project Number: DU PONT/18868/0CR. Unpublished study prepared by DuPont Crop Protection. 104 p.

48120069

- Wardrope, L. (2006) [Carbon 14]

- IN

- K5A77 (a Metabolite of [Carbon 14]

- DPX

HGW86): Batch Equilibrium (Adsorption/Desorption) in Five Soils. Project Number:

DUPONT/1760 7/0CR, 807016. Unpublished study prepared by Charles River Laboratories. 74 p.

48120068

- McCorquodale, G. (2010) IN

- K5A78 (a Metabolite of DPX

- HGW86): Batch Equilibrium (Adsorption/Desorption) in Five Soils. Project Number: DUPONT/17606, 806908/0CR. Unpub lished study prepared by Charles River Laboratories. 69 p.

### 170 48120067

- Morriss, A. (2007) IN

- JSE76 (a Metabolite of DPX

- HGW86): Batch Equilibrium (Adsorption/Desorption) in Five Soils. Project Number: DUPONT/17605/0CR, 806955. Unpublished study prepared by Charles River Laboratories. 68 p.

48120066

- Wardrope, L. (2006) [Carbon 14]

- IN

- JCZ38 (a Metabolite of [Carbon 14]

- DPX

HGW86): Batch Equilibrium (Adsorption/Desorption) in Five Soils. Project Number: DuPonU17604, 807021/0CR. Unpublished study prepared by Charles River Laboratories. 74 p.

48120065

- McCorquodale, G. (2007) [Carbon 14]

- IN

- J9Z38 (a Metabolite of DPX

- HGW86): Batch Equilibrium (Adsorption/Desorption) in Five Soils. Project Number: DUPONT/17603/0CR, 806997. Unpublished study p repared by Charles River Laboratories. 64 p.

48120064

- Morriss, A. (2006) Rate of Degradation of [Carbon 14]

- IN

- K5A77 in Five Aerobic

Soils. Project Number: DUPONT/17602/0CR, 806583. Unpublished study prepared by Charles River Laboratories. 118 p.

481200 63

- McCorquodale, G.; Wardrope, L. (2007) Rate of Degradation of [Carbon 14]

- IN

K5A78 in Five Aerobic Soils. Project Number: DUPONT/17599/0CR, 806714. Unpublished study prepared by Charles River Laboratories. 110 p.

48120062

- McCorquodale, G.; Wardrope, L. (2007) Rate of Degradation of [Carbon 14]

- IN

JSE76 in Five Aerobic Soils. Project Number: DUPONT/17598/0CR, 806981. Unpublished study prepared by Charles River Laboratories. 124 p.

48120061

- Wardrope, L. (2007) Rate of Degradation of [Carbon 14]

- IN

- JCZ 38 in Five Aerobic Soils. Project Number: DUPONT/17597/0CR, 807000. Unpublished study prepared by Charles River Laboratories. 132 p.

48120060

- McCorquodale, G. (2006) Rate of Degradation of [Carbon 14]

- IN

- J9Z38 in Five Aerobic Soils. Project Number: DUPON T/17596/0CR, 806541. Unpublished study prepared by Charles River Laboratories. 111 p.

48120058

- Thiel, A. (201 0) Terrestrial Field Dissipation of DPX

- HGW86 on Bare Soil in Texas, USA. Project Number: 7457/REVISION/N0/1, 50057/0CR. Unpublished study

prepa red by ABC Laboratories, Inc. 223 p.

48120057

- Thiel, A. (201 0) Terrestrial Field Dissipation of DPX

- HGW86 on Bare Soil in Manitoba, Canada. Project Number: DuPonU17068, 50055/0CR. Unpublished study prepared by ABC Laboratories, Inc. 203 p.

48120056

- Sh arma, A.; Rice, F.; Gant, A. (2009) Terrestrial Field Dissipation of DPX

- HGW86 Insecticide on Bare Soil and in the Presence of an Alfalfa Crop in Missouri, USA. Project Number: DuPonU17067, 50054/0CR. Unpublished study prepared by ABC Laboratories,

Inc. 36 1 p.

48120055

- Sharma, A.; Rice, F.; Gant, A. (2008) Terrestrial Field Dissipation of DPX

- HGW86 Insecticide on Bare Soil and in the Presence of a Leafy Vegetable Crop in California, USA. Project Number: DUPONT/17066/0CR; 50053. Unpublished study prepared by ABC Laboratories, Inc. 407 p.

48120054

- Sharma, A.; Rice, F.; Gant, A. (2009) Terrestrial Field Dissipation of DPX

- HGW86 Insecticide on Bare Soil and in the Presence of a Potato Crop in Washington, USA. Project Number: 7065/REVISION/N0/1, 50058/0CR. Unpublished study prepared by ABC Laboratories, Inc. 349 p.

### 171 48120053

- Thiel, A. (201 0) Terrestrial Field Dissipation of DPX

- HGW86 on Bare Soil in New York, USA. Project Number: DUPONT/17064/0CR, 50056. Unpublished study prepared by ABC Laboratories, Inc. 214 p.

48120049

- McCorquodale, G.; Wardrope, L. (2006) [Carbon 14]

- DPX

- HGW86: Degradability and Fate in the Sediment/Water System. Project Number: DUPONT/17059/0CR, 806316. Unpublished study prepared by Charles River Laboratories. 144 p.

48120047

- McCor quodale, G.; Wardrope, L. (2006) Anaerobic Soil Metabolism of [Carbon 14]

DPX

- HGW86. Project Number: DUPONT/17057/0CR, 806164. Unpublished study prepared by Charles River Laboratories. 93 p.

48120046

- Morriss, A. (2005) Photodegradation of [Carbon 14]

- DPX

- HGW86 on Soil. Project Number: DUPONT/17056/0CR, 806206. Unpublished study prepared by Charles River Laboratories. 82 p.

48120045

- Lowrie, C.; Coyle, D. (2006) Rate of Degradation and Aged Desorption of [Carbon 14]

- DPX

- HGW86 in Three Aerobic Soils. Proje ct Number: DUPONT/17055/0CR, 806274. Unpublished study prepared by Charles River Laboratories. 174 p.

48119907

- Hitata, C. M. (2007) DPX

- HGW86: Volatility, Calculation of Henry’s Law Constant. Project Number: DUPONT 18861. E. I. du Pont de Nemours and Co mpany, Stine

- Haskell Research Center Newark, Delaware 19714

- 0030, USA

48119906

- Morriss, A.; McCorquodale, G. (2007) Photodegradation of [Carbon 14]

- DPX

HGW86 in pH 4 Buffer and Natural Water. Project Number: DUPONT/17060/0CR,

806075. Unpublished study p repared by Charles River Laboratories. 184 p.

48119905

- Lowrie, C. (2005) Hydrolytic Stability of [14C]

- DPX

- HGW86 in Buffered Aqueous Solutions at pH 4, 7, and 9. Project Number: DUPONT 17058. Performing Laboratory Inveresk

, Tranent, Scotland, EH33 2 NE

48119901

- Clipson, A.S. and Craig, W.B. (2007) DPX

- HGW86: Laboratory Study of Water Solubility. Project Number: DUPONT 17050. Unpublished study prepared by Charles River Laboratories. 45 p.

### 172 Appendix A Screening Imbibition Program (SIP v. 1.0) Inputs and Outputs for the Proposed Uses of Cyantraniliprole

Table 1. Inputs

Parameter Value

Chemical name Cyantraniliprole
Solubility (in water at 25 o C; mg/L) 14.2

Mammalian LD 50 (mg/kg

- bw) 5000 Mammalian test species laboratory rat Body weight (g) of "other" mammalian species

Mammalian NOAEL (mg/kg

- bw) 20 Mammalian test species laboratory rat Body weight (g) of "other" mammalian species

Avian LD 50 (mg/kg

- bw) 2250
Avian test species northern bobwhite quail Body weight (g) of "other" avian species Mineau scaling factor 1.15

Mallard NOAEC (mg/kg

- diet) 1000 Bobwhite quail NOAEC (mg/kg

diet) 1000 NOAEC (mg/kg

- diet) for other bird species Body weight (g) of other avian species NOAEC (mg/kg

- diet) for 2nd other bird species Body weight (g) of 2nd other avian species

Table 2. Mammalian Results

Parameter Acute Chronic Upper bound exposure (mg/kg

bw) 2.4424 2.4424 Adjusted toxicity value (mg/kg

bw) 3845.8028 15.3832 Ratio of exposure to toxicity 0.0006 0.1588

Conclusion* Drinking water exposure
alone is NOT a potential

concern for mammals Drinking water exposure alone is NOT a potential concern for

mammals

### 173 Table 3. Avian Results

Parameter Acute Chronic Upper bound exposure (mg/kg

bw) 11.5020 11.5020 Adjusted toxicity value (mg/kg

bw) 1620.9664 49.6126 Ratio of exposure to acute toxicity 0.0071 0.2318

Conclusion* Drinking water exposure alone is NOT a potential
concern for birds Drinking water exposure alone is NOT a potential concern for
birds

*Conclusion is for drinking water exposure alone. This does not combine all routes of exposure. Therefore, when aggregated with other routes ( i.e ., diet, inhalation, dermal), pesticide exposure through drinking water may contribute to a total exposure that has potential fo r effects to non

- target animals.

### 174 Appendix B Sample Screening Tool for Inhalation Risk (STIR v. 1.0) Inputs and Outputs for the Proposed Uses of Cyantraniliprole



# Input

Application and Chemical Information

Enter Chemical Name Cyantraniliprole

Enter Chemical Use Agriculture and

Residential Is the Application a Spray? (enter y or n) y If Spray What Type (enter ground or air) air Enter Chemical Molecular Weight (g/mole) 473.72 Enter Chemical Vapor Pressure (mmHg) 3.85E

- 17 Enter Application Rate (lb a.i./acre) 0.69

Toxicity Properties

**Bird**

Enter Lowest Bird Oral LD 50 (mg/kg bw) 2250 Enter Mineau Scaling Factor 1.15 Enter Tested Bird Weight (kg) 0.178

**Mammal**

Enter Lowest Rat Oral LD 50 (mg/kg bw) 5000

Enter Lowest Rat Inhalation LC 50 (mg/L) 5.2 Duration of Rat Inhalation Study (hrs) 4 Enter Rat Weight (kg) 0.35



# Output

Results Avian (0.020 kg )
Maximum Vapor Concentration in Air at Saturation (mg/m 3 ) 9.81E

- 13

Maximum 1

- hour Vapor Inhalation Dose (mg/kg) 1.23E

- 13

Adjusted Inhalation LD 50 1.30E+01

Ratio of Vapor Dose to Adjusted Inhalation LD 50 9.46E

- 15 Exposure not Likely Significant

Maximum Post

- treatment Spray Inhalation Dose (mg/kg) 6.63E

- 02 Ratio of Droplet Inhalation Dose to Adjusted Inhalation

LD 50 5.08E

- 03 Exposure not Likely Significant



### Results Mammalian (0.015 kg )
Maximum Vapor Concentration in Air at Saturation (mg/m 3 ) 9.81E

- 13

Maximum 1

- hour Vapor Inhalation Dose (mg/kg) 1.55E

- 13

Adjusted Inhalation LD 50 3.10E+02

Ratio of Vapor Dose to Adjusted Inhalation LD 50 5.01E

- 16 Exposure not Likely Significant

Maximum Post

- treatment Spray Inhalation Dose 8.33E

- 02

### 175 (mg/kg)
Ratio of Droplet Inhalation Dose to Adjusted Inhalation

LD 50 2.69E

- 04 Exposure not Likely Significant

### Appendix C Cyantraniliprole and Its Major and Minor Environmental Degradates

Code Name/ Synonym Chemical Name Chemical Structure Study Type MRID Maximum %AR (day) Final %AR (study length)

PARENT

Cyantraniliprole

DPX

- HGW86 CAS Name : 3

- Bromo

- 1

- (3

- chloro

- 2

- p yridinyl)

- N

- [4

- cyano

- 2

- methyl

- 6 [(methylamino)carbonyl]phenyl]

- 1 H

- pyrazole

- 5

- carboxamide

CAS Number: 736994

- 63

- 1

Formula : C 19 H 14 BrClN 6 O 2

MW: 472 g/mol

SMILES: Not Available Hydrolysis pH 4 at 25oC

48119905 92.86 (30 days)
Hydrolysis pH 7 at 25oC 52.79 (30 days)
Hydrolysis pH 9 at 25oC 2.21 (30 days)
Aqueous P hotolysis 48119906

48122540 ND (15 days) [LD 5.47 (1 days)]

Soil P hotolysis (moist

- soil) 48120082 ND (30 days) [LD 12.40 (20 days)]

Soil P hotolysis (air

- dry soil) 48120046 84.11 (30 days)

Aerobic Soil Metabolism 48120045 57.70 (120 days)

48120043 12.02 (358 days)

Anaerobic Soil Metabolism 48120047 1.20 (120 days)

Aerobic A quatic Metabolism 48120049 8.26 (100 days)

Anaerobic A quatic Metabolism 48120071 0.15 (353 days)

48120081 4.00 (100 days)



### MAJOR (>10%) TRANSFORMATION PRODUCTS

CAS Name : 2

- [3

- Bromo

- 1

- (3

- Hydrolysis pH 7 at 25oC 48119905 48.87 (30 days) 48.87 (30 days) N N

N N H

O Cl Br

N H O

N

Br

### 177 Code Name/ Synonym Chemical Name Chemical Structure Study Type MRID Maximum %AR (day) Final %AR (study length)

Hydrolysis pH 9 at 25oC 97.84 (10 days) 95.40 (30 days)

Soil P hotolysis (moist

- soil) 48120082 54.82 (10 days) 30.08 (30 days)

Aerobic Soil Metabolism 48120045 19.39 (120 days) 19.39 (120 days)

48120043 15.98 (16 days) 5.05 (358 days)

Anaerobic Soil Metabolism 48120047 71.88 (30 days) 68.35 (120 days)

Aerobic A quatic Metabolism 48120049 71.74 (56 days) 68.64 (100 days)

Anaerobic A quatic Metabolism 48120071 77.20 (28 days) 58.03 (353 days)

48120081 82.03 (100 days) 81.14 (100 days) Hydrolysis pH 4 at 25oC 48119905 7.79 (30 days) 7.79 (30 days)

Soil P hotolysis (air

- dry soil) 48120046 8.86 (15 days) 8.86 (15 days)



### IN

- NXX69 CAS Name : 2

- [[(4Z)

- 2

- bromo

4H

- pyrazolo[1,5

- d]pyrido[3,2

- b][1,4]oxazin

- 4

- ylidene]amino]

- 5

- cyano

- N,3

- dimethylbenzamide

CAS Number: Not Assigned

Formula : C 19 H 13 Br N 6 O 2

MW: 437 g/mol

SMILES: Not Available Aqueous Photolysis 48119906

48122540 100.67 (2 days) 79.23 (15 days)



### IN

- QKV54 CAS Name : 2

- (3

- Bromo

- 1H

pyrazol

- 5

- yl)

- 1,4

- dihydro

- 3,8

- dimethyl

- 4

- oxo

- 6

- quinazolinecarbonitrile

CAS Number: Not Assigned

Formula : C 14 H 1 0 Br N 5 O

MW: 344 g/mol

SMILES: Not Available Soil P hotolysis (moist

- soil) 48120082 17.18 (15 days) 5.83 (30 days)

CAS Name : 2

- (2

- Bromo

- 4

- Soil P hotolysis (moist

- soil) 48120082 14.12 (30 days) 14.12 (30 days) N N

N N

O Br

N H O

N



### N

N O

N N H Br N

### 178 Code Name/ Synonym Chemical Name Chemical Structure Study Type MRID Maximum %AR (day) Final %AR (study length)

IN

- RNU71 oxopyrazolo[1,5

- a]pyrido[3,2

- e]pyrazin

- 5(4H)

- yl)

- 5

- cyano

- N,3

- dimethylbenzamide

CAS Number: Not Assigned

Formula : C 19 H 1 3 Br N 6 O 2

MW: 437 g/mol

SMILES: Not Available Aqueous P hotolysis 48119906

48122540 7.46 (15 days) 7.46 (15 days)



### IN

- JSE76 CAS Name : 4

- [[[3

- Bromo

- 1

- (3

- chloro

- 2

- pyridinyl)

- 1H

- pyrazol

- 5

- yl]carbonyl]amino]

- 3

- methyl

- 5

- [(methylamino)carbonyl]benzoic

acid

CAS Number: Not Assigned

Formula : C 19 H 1 5 BrCl N 5 O 4

MW: 491 g/mol

SMILES: Not Available Aerobic Soil Metabolism 48120045 33.28 (120 days) 33.28 (120 days)

48120043 42.90 (358 days) 42.90 (358 days)

Soil P hotolysis (moist

- soil) 48120082 4.19 (30 days) 4.19 (30 days)

Anaerobic Soil Metabolism 48120047 5.82 (14 days) ND (120 days) [LD 4.65 (30 days)]

Aerobic A quatic Metabolism 48120049 0.79 (56 days) ND (100 days) [LD 0.79 (56 days)]



### IN

- JCZ38 CAS Name : 4

- [[[3

- Bromo

- 1

- (3

- chloro

- 2

- pyridinyl)

- 1H

- pyrazol

- 5

- yl]carbonyl]amino]

- N'3',5

- dimethyl

- 1,3

- benzenedicarboxamide

CAS Number: Not Assigned

Formula : C 19 H 1 6 BrCl N 6 O 3

MW: 490 g/mol

SMILES: Not Available Aerobic Soil Metabolism 48120045 39.60 (120 days) 39.60 (120 days)

48120043 16.58 (7 days) ND (358 days) [LD 0.20 (238 days)]

Soil P hotolysis (moist

- soil) 48120082 3.35 (20 days) 2.63 (30 days)

Anaerobic Soil Metabolism 48120047 3.62 (7 days) ND (120 days) [LD 1.62 (30 days)] 

### O N H N

N N N O Br

N

N H O

O N N

N Cl Br

O

O H N H

O

N H 2 O N H

N H

O N N

N Cl Br

### 179 Code Name/ Synonym Chemical Name Chemical Structure Study Type MRID Maximum %AR (day) Final %AR (study length)

IN

- K5A78 CAS Name : 2

- [3

- Bromo

- 1

- (3

- chloro

- 2

- pyridinyl)

- 1H

- pyrazol

- 5

- yl]

- 3,4

- dihydro

- 3,8

- dimethyl

- 4

-

oxo

- 6

- quinazolinecarboxylic acid

CAS Number: Not Assigned

Formula : C 19 H 1 3 BrCl N 5 O 3

MW: 473 g/mol

SMILES: Not Available Aerobic Soil Metabolism 48120045 10.53 (120 days) 10.53 (120 days)

48120043 28.78 (358 days) 28.78 (358 days)

Anaerobic Soil Metabolism 48120047 16.17 (120 days) 16.17 (120 days)

Aerobic A quatic Metabolism 48120049 0.61 (84 days) ND (100 days) [LD 0.61 (84 days)]

Anaerobic A quatic Metabolism 48120071 9.18 (353 days) 9.18 (353 days)


### IN

- PLT97 CAS Name : 2

- [3

- Bromo

- 1

- (3

- chloro

- 2

- pyridinyl)

- 1H

- pyrazol

- 5

- yl]

- 1,4

- dihydro

- 8

- methyl

- 4

- oxo

- 6

- quinazolinecarboxylic acid

CAS Number: Not Assigned

Formula : C 18 H 1 1 BrCl N 5 O 3

MW: 460 g/mol

SMILES: Not Available Aerobic Soil Metabolism 48120043 26.27 (358 days) 26.27 (358 days)



### Unidentified
Radioactivity Soil P hotolysis (moist

- soil) 48120082 10.34 (30 days) 10.34 (30 days)

Anaerobic A quatic Metabolism 48120071 31.74 (260 days) 29.22 (353 days) Aqueous P hotolysis 48119906

48122540 3.83 (15 days) 3.83 (15 days)

Soil P hotolysis (air

- dry soil) 48120046 4.50 (1 days)

--

Aerobic Soil Metabolism 48120045 3.57 (120 days) 3.57 (120 days)

Anaerobic Soil Metabolism 48120047 1.73 (7 days) ND (120 days) [LD 1.59 (90 days)] O H O N

N O

N N

N Br

Cl

O H O N N H

N N O

N Br

Cl

### 180 Code Name/ Synonym Chemical Name Chemical Structure Study Type MRID Maximum %AR (day) Final %AR (study length)

Aerobic A quatic Metabolism 48120049 1.72 (56 days) 0.99 (100 days)

Anaerobic Aquatic Metabolism 48120081 6.43 (45 days) 5.33 (100 days)


### Non

- Extractable Radioactivity Soil P hotolysis (moist

- soil) 48120082 28.83 (30 days) 28.83 (30 days)

Aerobic Soil Metabolism 48120045 18.72 (30 days) 18.72 (120 days)

Aerobic A quatic Metabolism 48120049 12.70 (100 days) 12.70 (100 days)

Soil P hotolysis (air

- dry soil) 48120046 6.65 (15 days) 6.65 (15 days)

Anaerobic Soil Metabolism 48120047 6.15 (120 days) 6.15 (120 days) Anaerobic Aquatic Metabolism 48120081 5.84 (100 days) 5.84 (100 days)



### MINOR (< 10%) TRANSFORMATION PRODUCTS

IN

- QKV55 CAS Name : Not Assigned

CAS Number: Not Assigned

Formula : C 19 H 1 6 Br N 6 O

MW: Not Available

SMILES: Not Available Aqueous P hotolysis 48119906

48122540 6.26 (15 days) 6.26 (15 days)



### IN

- NXX70 CAS Name : 2

- [3

- Bromo

- 1

- (3

- hydroxy

- 2

- pyridinyl)

- 1H

- pyrazol

5

- yl]

- 3,4

- dihydro

- 3,8

- dimethyl

- 4

-

oxo

- 6

- quinazolinecarbonitrile

CAS Number: Not Assigned

Formula : C 19 H 1 3 Br N 6 O 2

MW: 437 g/mol

SMILES: Not Available Aqueous P hotolysis 48119906

48122540 5.38 (15 days) 5.38 (15 days)

Soil P hotolysis (moist

- soil) 48120082 4.79 (6 days) ND (30 days) [LD 1.42 (20 days)]

CAS Name : 2

- [3

- Bromo

- 1

- (3

- chloro

- 2

- pyridinyl)

- 1H

- pyrazol

- 5

- Soil P hotolysis (moist

- soil) 48120082 1.95 (20 days) ND (30 days) [LD 1.95 (20 days)] N O N

N N

N Br

O H

N

### 181 Code Name/ Synonym Chemical Name Chemical Structure Study Type MRID Maximum %AR (day) Final %AR (study length)

IN

- K5A77 yl]

- 3,4

- dihydro

- 3,8

- dimethyl

- 4

-

oxo

- 6

- quinazolinecarboxamide

CAS Number: Not Assigned

Formula : C 19 H 1 4 BrCl N 6 O 2

MW: 473 g/mol

SMILES: Not Available Aerobic Soil Metabolism 48120045 6.24 (30 days) 5.54 (120 days)

48120043 8.93 (100 days) 4.83 (358 days)

Anaerobic Soil Metabolism 48120047 9.97 (60 days) 7.46 (120 days)

Aerobic A quatic Metabolism 48120049 2.00 (100 days) 2.00 (100 days)

Anaerobic A quatic Metabolism 48120071 7.24 (353 days) 7.24 (353 days)

48120081 2.48 (100 days) 2.48 (100 days)



### IN

- K5A79 CAS Name : 3

- (Aminocarbonyl)

- 4

- [[[3

- bromo

- 1

- (3

- chloro

- 2

- pyridinyl)

- 1H

- pyrazol

- 5

- yl]carbonyl]amino]

- 5

- methylbenzoic acid

CAS Number: Not Assigned

Formula : C 18 H 1 3 BrCl N 5 O 4

MW: 478 g/mol

SMILES: Not Available Soil P hotolysis (moist

- soil) 48120082 2.97 (30 days) 2.97 (30 days)

Aerobic Soil Metabolism 48120045 2.99 (120 days) 2.99 (120 days)

48120043 9.34 (41 days) 2.18 (358 days)



### IN

- K7H19 CAS Name : 4

- [[[3

- Bromo

- 1

- (3

- chloro

- 2

- pyridinyl)

- 1H

- pyrazol

- 5

- yl]carbonyl]amino]

- 5

- methyl

- 1,3

- benzenedicarboxamide

CAS Number: Not Assigned

Formula : C 18 H 1 4 BrCl N 6 O 3

MW: 477 g/mol

SMILES: Not Available Soil P hotolysis (moist

- soil) 48120082 5.93 (30 days) 5.93 (30 days)

Aerobic Soil Metabolism 48120045 1.58 (120 days) 1.58 (120 days)

Aqueous P hotolysis 48119906

48122540 0.25 (15 days) 0.25 (15 days) N H 2 O N

N O N
N

N Br

Cl

N H O N H 2

O N N

N Cl Br

O

O H



### N H O N H 2



### O N N

N Cl Br

O

N H 2

### 182 Code Name/ Synonym Chemical Name Chemical Structure Study Type MRID Maximum %AR (day) Final %AR (study length)

Carbon

Dioxide CAS Number : 124

- 38

- 9

Formula: CO 2 MW: 44.1 g/mol Soil P hotolysis (air

- dry soil) 48120046 < LOQ < LOQ (15 days)

Aerobic Soil Metabolism 48120045 1.58 (30 days) 1.58 (120 days)

Anaerobic Soil Metabolism 48120047 < LOQ < LOQ (120 days)

Aerobic A quatic Metabolism 48120049 0.20 (70 days) <LOQ (100 days)

ND = Not Detected

LD = Last Detected

-- = No result applicable LOQ = Limit of Quantitation Major d egradates that continued to increase by study termin ation include IN

- J9Z38 , IN

- RNU71, IN

- JSE76, IN

- JCZ38, IN

- K5A78 , IN

- PLT97. 

## C O O

### Appendix D : Example Surface Water PRZM/EXAMS Output for Aerial Use on NC Cotton

stored as Cotton3A.out
Chemical: Cyantraniliprole

PRZM environment: NCcottonSTD.txt modified Tueday, 29 May 2007 at 12:58:38
EXAMS environment: pond298.exv modified Tueday, 26 August 2008 at 05:14:07

Metfile: w13722.dvf modified Tueday, 26 August 2008 at 05:14:27
Water segment concentrations (ppb)

Year Peak 96 hr 21 Day 60 Day 90 Day Yearly

1961 2.585 2.582 2.571 2.073 1.567 0.3863

1962 10.16 10.15 10.1 9.704 7.328 3.563

1963 16.4 16.37 16.28 15.78 13.35 10.11

1964 15.95 15.94 15.88 15.76 15.66 14.53

1965 14.71 14.7 14.66 14.56 14.48 13.39

1966 16.24 16.22 16.14 16.05 14.66 12.77

1967 15.99 15.98 15.93 15.76 15.59 14.75

1968 24.83 24.81 24.7 24.46 22.65 16.54

1969 24.24 24.23 24.15 23.99 23.85 21.93

1970 26.91 26.88 26.78 26.54 24.02 20.42

1971 26.16 26.14 26.07 25.89 25.74 24.28

1972 26.25 26.22 26.18 25.82 25.04 23.74

1973 25.7 25.68 25.61 25.44 25.28 23.19

1974 22.76 22.74 22.65 22.47 22.32 20.74

1975 29.06 29.02 28.87 26.85 23.66 20.21

1976 31.89 31.86 31.79 31.58 29.85 26.83

1977 36.56 36.51 36.34 35.98 33.57 30.08

1978 35.61 35.59 35.49 35.29 35.11 32.34

1979 34.63 34.59 34.43 34.11 31.46 29.86

1980 33.82 33.79 33.69 33.46 33.29 30.51

1981 36.57 36.52 36.34 35.97 33 28.72

1982 38.12 38.08 37.94 37.58 35.59 33.28

1983 38.91 38.87 38.74 38.43 36.63 34.78

1984 38.21 38.19 38.08 37.82 37.6 34.31

1985 31.42 31.41 31.33 31.15 30.97 29

1986 30.81 30.79 30.7 30.49 30.3 27.59

1987 26.12 26.1 26.03 25.87 25.73 23.71

1988 27.87 27.84 27.72 27.44 25.21 22.27

1989 27.44 27.41 27.31 27.14 26.56 25.07

1990 30.63 30.58 30.42 30.12 28.28 25.42

Sorted results

Prob. Peak 96 hr 21 Day 60 Day 90 Day Yearly

0.03 38.91 38.87 38.74 38.43 37.60 34.78

0.06 38.21 38.19 38.08 37.82 36.63 34.31

0.10 38.12 38.08 37.94 37.58 35.59 33.28

0.13 36.57 36.52 36.34 35.98 35.11 32.34

0.16 36.56 36.51 36.34 35.97 33.57 30.51

0.19 35.61 35.59 35.49 35.29 33.29 30.08

0.23 34.63 34.59 34.43 34.11 33.00 29.86

0.26 33.82 33.79 33.69 33.46 31.46 29.00

0.29 31.89 31.86 31.79 31.58 30.97 28.72

0.32 31.42 31.41 31.33 31.15 30.30 27.59

0.35 30.81 30.79 30.70 30.49 29.85 26.83

0.39 30.63 30.58 30.42 30.12 28.28 25.42

0.42 29.06 29.02 28.87 27.44 26.56 25.07

0.45 27.87 27.84 27.72 27.14 25.74 24.28

0.48 27.44 27.41 27.31 26.85 25.73 23.74

0.52 26.91 26.88 26.78 26.54 25.28 23.71

0.55 26.25 26.22 26.18 25.89 25.21 23.19

0.58 26.16 26.14 26.07 25.87 25.04 22.27

0.61 26.12 26.10 26.03 25.82 24.02 21.93

0.65 25.70 25.68 25.61 25.44 23.85 20.74

0.68 24.83 24.81 24.70 24.46 23.66 20.42

0.71 24.24 24.23 24.15 23.99 22.65 20.21

0.74 22.76 22.74 22.65 22.47 22.32 16.54

0.77 16.40 16.37 16.28 16.05 15.66 14.75

0.81 16.24 16.22 16.14 15.78 15.59 14.53

0.84 15.99 15.98 15.93 15.76 14.66 13.39

0.87 15.95 15.94 15.88 15.76 14.48 12.77

0.90 14.71 14.70 14.66 14.56 13.35 10.11

0.94 10.16 10.15 10.10 9.70 7.33 3.56

0.97 2.59 2.58 2.57 2.07 1.57 0.39

0.10 37.97 37.92 37.78 37.42 35.54 33.19

Average 22.48

Inputs generated by pe5.pl

- Novemeber 2006

Data used for this run:
Output File: Cotton3A

Metfile: w13722.dvf

PRZM scenario: NCcottonSTD.txt

EXAMS environment file: pond298.exv

Chemical Name: Cyantraniliprole

Description Variable N Value Units Comments
Molecular weight mwt 473.72 g/mol

Henry's Law Const. henry 1.70E

- 18 atm

- m^3/mol

Vapor Pressure vapr 3.85E

- 17 torr
Solubility sol 14.2 mg/L

Kd Kd mg/L

Koc Koc 14 mg/L

Photolysis half

- life kdp 88 days Half

- life
Aerobic Aquatic Metabolism kbacw 589 days Halfife
Anaerobic Aquatic Metabolism kbacs 961 days Halfife

Aerobic Soil Metabolism asm 1327 days Halfife
Hydrolysis: pH 7 0 days Half

- life

Method: CAM 2 integer See PRZM manual
Incorporation Depth: DEPI cm Application Rate: TAPP 0.149 kg/ha

Application Efficiency: APPEFF 0.95 fraction
Spray Drift DRFT 0.05 fraction of application rate applied to pond
Application Date Date 10

- Nov dd/mm or dd/mmm or dd

- mm or dd

- mmm

Interval 1 interval 7 days Set to 0 or delete line for single app.

app. rate 1 apprate 0.149 kg/ha

Interval 2 interval 7 days Set to 0 or delete line for single app.

app. rate 2 apprate 0.149 kg/ha

Record 17: FILTRA

IPSCND 1

UPTKF

Record 18: PLVKRT

PLDKRT

FEXTRC 0.5
Flag for Index Res. Run IR EPA Pond
Flag for runoff calc. RUNOFF none none, monthly or total(average of entire run)

### 184 Appendix E Sample T

- REX Input and Ou tput for the Proposed Uses of Cyantraniliprole

Brassica Leafy Vegetables (3 apps at 0.133 lb ai/A

– 5

- day interval)

Summary of Risk Quotient Calcul ations Based on Upper Bound Kenaga EECs

Upper Bound Kenaga, Acute Avian Dose

- Based Risk Quotients

Size

Class (grams) Adjusted

LD50 EECs and RQs

Short Grass Tall Grass Broadleaf

Plants Fruits/Pods/

Seeds Arthropods Granivore

EEC RQ EEC RQ EEC RQ EEC RQ EEC RQ EEC RQ

20 0.00 99.10 N/A 45.42 N/A

55.75 N/A

6.19 N/A

38.82 N/A

1.38 N/A

100 0.00 56.51 N/A 25.90 N/A 31.79 N/A 3.53 N/A 22.13 N/A 0.78 N/A

1000 0.00 25.30 N/A

11.60 N/A

14.23 N/A

1.58 N/A

9.91 N/A

0.35 N/A

Upper Bound Kenaga, Subacute Avian Dietary Based Risk Quotients

LC50 EECs and RQs

Short Grass Tall Grass Broadleaf Plants Fruits/Pods/Seeds Arthropods

EEC RQ EEC RQ EEC RQ EEC RQ EEC RQ

0 8 7.02 N/A 39.88 N/A 48.95 N/A 5.44 N/A 34.08 N/A

Size class not used for dietary risk quotients

Upper Bound Kenaga, Chronic Avian Dietary Based Risk Quotients

NOAEC (ppm) EECs and RQs

Short Grass Tall Grass Broadleaf Plants Fruits/Pods/Seeds Arthropods

EEC RQ EEC RQ EEC RQ EEC RQ EEC RQ

100 0 87.02 0.09 39.88 0.04 48.95 0.05 5.44 0.01 34.08 0.03

Upper Bound Kenaga, Acute Mammalian Dose

- Based Risk Quotients

### 185 Size

Class (grams) Adjuste

d

LD50 EECs and RQs

Short Grass Tall Grass Broadleaf

Plants Fruits/Pods/

Seeds Arthropods Granivore

EEC RQ EEC RQ EEC RQ EEC RQ EEC RQ EEC RQ

15 0.00 82.96 N/A 38.02 N/A 46.67 N/A 5.19 N/A 32.4938 N/A 1.1523 N/A

35 0.00 57.34 N/A 26.28 N/A 32.25 N/A 3.58 N/A 22.4576 N/A 0.7964 N/A

1000 0.00 13.29 N/A 6.09 N/A 7.48 N/A 0.83 N/A 5.20687 N/A 0.1846 N/A

Upper Bound Kenaga, Acute Mammalian Dietary Based Risk Quotients

LC50 (ppm) EECs and RQs

Short Grass Tall Grass Broadleaf

Plants Fruits/Pods/Seeds Arthropods

EEC RQ EEC RQ EEC RQ EEC RQ EEC RQ

0 8 7.02 N/A 39.8

8 N/A 48.95 N/A 5.44 N/A 34.08 N/A

Size class not used for dietary risk quotients

Upper Bound Kenaga, Chronic Mammalian Dietary Based Risk Quotients

NOAEC (ppm) EECs and RQs

Short Grass Tall Grass Broadleaf

Plants Fruits/Pods/Seeds/Larg

e Insects Arthropods

EEC RQ EEC RQ EEC RQ EEC RQ EEC RQ

20 87.02 4.35 39.88 1.99 48.95 2.45 5.44 0.27 34.08 1.70 Size class not used for dietary risk quotients

Upper Bound Kenaga, Chronic Mammalian Dose

- Based Risk Quotients

Size

Class (grams) Adjusted

NOAEL EECs and RQs

Short Grass Tall Grass Broadleaf

Plants Fruits/Pods/

Seeds Arthropods Granivore

EEC RQ EEC RQ EEC RQ EEC RQ EEC RQ EEC RQ

15 0.00 82.96 N/A 38.02 N/A 46.67 N/A 5.19 N/A 32.49 N/A 1.15 N/A

35 0.00 57.34 N/A 26.28 N/A 32.25 N/A 3.58 N/A 22.46 N/A 0.80 N/A

1000 0.00 13.29 N/A 6.09 N/A 7.48 N/A 0.83 N/A 5.21 N/A 0.18 N/A

### 186 Appendix F EEC Calculations for Soil Drench/Injection, Drip Chemigation, and Pot Drench Applications

Soil Injection/ Soil Drench /Drip Irrigation and Woody Potted Ornamental Drench Leaf

Biomass Estimate s

General hardwood equation for dry weight ( Sollins et al., 1973)

ln leaf biomass (kg) =

- 3.862 + 1.74*(ln(dbh 1 

### ))

For the soil injection/soil drench scenario s , a diameter at breast height (DBH) of 6 inches (15.24 cm) is used. This DBH was selected base d on the Biological and Economic Analysis Division’s (BEAD) assumption that the average sized tree in an acre of urban

trees has a DBH of 6 inches (USEPA 2011a).

ln leaf biomass (kg) =

- 3.862 + 0*15.24 + 1.74*(ln(15.24 1 

### ))

ln leaf biomass (kg) =

- 3.862 + 0 + 4.74 ln leaf biomass (kg) = 0.878

Leaf biomass = e 0.878 

### = 2.4 kg

The correction for bias when converting from ln to arithmetic units = 1.34 (Sollins et al., 1973). Therefore: Leaf biomass = 2.4*1.34 = 3.216 kg dry weight

For leaves, 85 percent (mean) of the wet weight is water (USEPA, 1993); therefore , the general equation to convert leaf dry weight into wet weight is:

Leaf wet weight = (100% total leaf weight) *(kg of leaf dry weight) / (% leaf dry weight)

Ha rdwood leaf wet weight = (100%)*(3.216 kg) / (15%) Hardwood (6

- inch DBH) leaf wet weight = 21.44 kg wet weight

A similar calculation is performed for the woody potted ornamental drench scenario; however, a DBH of 1 inch (2.54 cm) is assumed because woody potted ornamentals are

small.

ln leaf biomass (kg) =

- 3.862 + 0*2.54 + 1.74*(ln(2.54 1 

### )) ln leaf biomass (kg) =

- 3.862 + 0 + 1.621 ln leaf biomass (kg) =

- 2.241

Leaf biomass = e - 2.241 

### = 0.106 kg

The correction for bias when converting from ln to arithmeti c units = 1.34 (Sollins et al., 1973). Therefore: Leaf biomass = 0.106*1.34 = 0.142 kg dry weight

### 187 For leaves, 85 percent of the wet weight is water (USEPA, 1993); therefore, the general equation to convert leaf dry weight into wet weight is:

Wet weight = (100% total weight) *(kg of dry weight) / (% dry weight)

Hardwood leaf wet weight = (100%)*(0.142 kg) / (15%) Hardwood (1

- inch DBH) leaf wet weight = 0.95 kg wet weight

General softwood equation for dry weight (Sollins et al., 1973)

ln leaf b iomass (kg) =

- 2.907 + 0*dbh + 1.674*(ln(dbh 1 

### ))

For the soil injection and soil drench scenario s , a DBH of 6 inches (15.24 cm) is used. This DBH was selected based on BEAD’s assumption that the average sized tree in an

acre of tr ees has a DBH of 6 inches (USEPA 2011 a ).

ln leaf biomass (kg) =

- 2.907 + 0*15.24 + 1.674*(ln(15.24 1 

### )) ln leaf biomass (kg) =

- 2.907 + 0 + 4.56 ln leaf biomass (kg) = 1.653

Leaf biomass = e 1.653 

### = 5.222 kg

The correction for bias when converting from ln to arithmetic units = 1.34 (Sollins et al., 1973). Therefore: Leaf biomass = 5.222*1.34 = 7 kg dry weight

For leaves, 85 percent of the wet weight is water (USEPA, 1993); therefore, the general equation to convert leaf dry weight into wet weight is:

Wet weight = (100% total weig ht) *(kg of dry weight) / (% dry weight)

Softwood leaf wet weight = (100%)*(7 kg) / (15%) Softwood (6

- inch DBH) leaf wet weight = 47 kg wet weight

A similar calculation is performed for the woody potted ornamental drench scenario; however, a DBH of 1 inch (2.54 cm) is assumed because woody potted ornamentals are

small.

ln leaf biomass (kg) =

- 2.907 + 0*2.54 + 1.674*(ln(2.54 1 

### )) ln leaf biomass (kg) =

- 2.907 + 0 + 1.56 ln leaf biomass (kg) =

- 1.347

Leaf biomass = e - 1.347 

### = 0.26 kg

The correction for bias when converting from ln to arithmetic units = 1.34 (Sollins et al., 1973). Therefore: Leaf biomass = 0.26*1.34 = 0.35 kg dry weight

### 188 For leaves, 85 percent of the wet weight is water (USEPA, 1993); therefore, the general equation to convert leaf dry weight into wet weight is:

Wet weight = (100% total weight) *(kg of dry weight) / (% dry weight)

Softwood leaf wet weight = (100%)*(0.35 kg) / (15%) Softwood (1

- inch DBH) leaf wet weight = 2.3 kg wet weight

Soil Injection and Drench for Ornamental Trees and Citrus The seasonal maximum application rates for ornamental trees range from 0.26 to 0.42 lb ai/A; the seasonal maximum application rate for citrus is 0.391 lb ai/A. Seasonal

maximums were chosen because multiple appl ications of cyantraniliprole are expected to accumulate in the plants. USEPA 2011 a established that on average, there are 36 trees

per acre in urban settings . Thus:

Ornamental trees = (0.26 lb ai /A) / (36 trees/A) = 0.007 lb ai/tree Ornamental trees = ( 0.42 lb ai/A) / (36 trees/A) = 0.012 lb ai/tree Citrus = (0.391 lb ai/A) / (36 trees/A) = 0.011 lb ai/tree

Conversion to mg (ornamental trees) = (0.007 lb ai)*(453592 mg ai/lb) = 3175 mg ai/tree Conversion to mg (ornamental trees) = (0.012 lb ai)*(453592 mg ai/lb) = 5443 mg ai/tree Conversion to mg (citrus) = (0.011 lb ai)*(453592 mg ai/lb) = 4990 mg ai/tree

It is assumed that the entire application of cyantraniliprole will accumulate in the leaves (a surrogate for other non

- woody food items such as seeds ) of the tree. To determine the dietary concentration (EEC) of cyantraniliprole in the leaves of hardwoods and softwoods, the cyantraniliprole application per tree is divided by the leaf biomass (Table 13).

Hardwoods ornamentals = (3175 mg ai/tree) / 21. 44 kg = 148 mg ai/kg

- leaves Hardwoods ornamentals = (5443 mg ai/tree) / 21.44 kg = 254 mg ai/kg

- leaves Citrus = (4990 mg ai/tree) / 21.44 kg = 233 mg ai/kg

- leaves

Softwoods ornamentals = (3175 mg ai/tree) / 47 kg = 68 mg ai/kg

- leaves

Softwoods ornamentals = (5443 mg ai/tree) / 47 kg = 116 mg ai/kg

- leaves

The EECs must be adjusted for mammal body weight. The T

- REX analysis uses three size classes for mammals: 15, 35, and 1000 g. According to the T

- REX User’s Manual, a 15 g mammal consumes 95 percent of i ts body weight daily, a 35 g mammal consumes 66 percent of its body weight daily, and a 1000 g mammal consumes 15 percent of its body weight daily. Consequently, the general equation for determining the dose of cyantraniliprole received per day is:

EEC m g ai/kg

- bw = (dietary concentration mg ai/kg

- diet)*(body weight consumption kg

diet/kg

- bw)

Hardwoods ornamentals

### 189 15 g mammal EEC = (148 mg ai/kg

- diet)*(0.95 kg

- diet/kg

- bw) = 141 mg ai/kg

- bw 35 g mammal EEC = (148 mg ai/kg

- diet)*(0.66 kg

- diet/kg

- bw) = 100 mg ai/kg

- bw 1000 g mammal EEC = (148 mg ai/kg

- diet)*(0.15 kg

- diet/kg

- bw) = 22 mg ai/kg

- bw

Hardwoods ornamentals 15 g mammal EEC = (254 mg ai/kg

- diet)*(0.95 kg

- diet/kg

- bw) = 241 mg ai/kg

- bw 35 g mammal EEC = (254 mg ai/kg

- diet)*(0.66 kg

- diet/kg

- bw) = 168 mg ai/kg

- bw 1000 g mammal EEC = (254 mg ai/kg

- diet)*(0.15 kg

- diet/kg

- bw) = 38 mg ai/kg

- bw

Citrus 15 g mammal EEC = (233 mg ai/kg

- diet)*(0.95 kg

- diet/kg

- bw) = 221 mg ai/kg

- bw 35 g mammal EEC = (233 mg ai/kg

- diet)*(0.66 kg

- diet/kg

- bw) = 154 mg ai/kg

- bw

1000 g mammal EEC = (233 mg ai/kg

- diet)*(0.15 kg

- diet/kg

- bw) = 35 mg ai/kg

- bw

Softwoods ornamentals 15 g mammal EEC = (68 mg ai/kg

- diet)*(0.95 kg

- diet/kg

- bw) = 65 mg ai/kg

- bw 35 g mammal EEC = (68 mg ai/kg

- diet)*(0.66 kg

- diet/kg

- bw) = 45 mg ai/kg

- bw 1000 g ma mmal EEC = ( 68 mg ai/kg

- diet)*(0.15 kg

- diet/kg

- bw) = 10 mg ai/kg

- bw

Softwoods ornamentals 15 g mammal EEC = (116 mg ai/kg

- diet)*(0.95 kg

- diet/kg

- bw) = 110 mg ai/kg

- bw 35 g mammal EEC = (116 mg ai/kg

- diet)*(0.66 kg

- diet/kg

- bw) = 77 mg ai/kg

- bw

10 00 g mammal EEC = (116 mg ai/kg

- diet)*(0.15 kg

- diet/kg

- bw) = 17 mg ai/kg

- bw

Non

- Woody Potted Ornamental Drench and Agricultural Drip Irrigation Leaf biomass equations were not available for non

- woody plants. Therefore, the assumption was made that the entire application of cyantraniliprole would concentrate in the plant.

The seasonal maximum application rates for potted ornamentals are 0.26 and 0.5 lb ai/A. The seasonal maximum application rates for agricultural crops are 0.4 (brassica vegetables, cucurbits, fruiting vegetables, leafy vegetables, and corm and tuberous vegetables). The seasonal maximum application rate was chosen because it is assumed that cyantraniliprole will accumulate in the plant as multiple applications occur (application inte rvals are usually 7 to 10 days).

For the potted ornamental scenario, 49,000 8

- inch pots are expected to fit into an acre of storage area at a typical nursery. Thus,

(0.26 lb ai/A) / 49,000 = 0.000005 lb ai/plant (0.5 lb ai/A) / 49,000 = 0.00001 lb ai/ plant

Conversion to mg = (0.000005 lb ai)*(453592 mg ai/lb) = 2.3 mg ai/plant Conversion to mg = (0.00001 lb ai)*(453592 mg ai/lb) = 4.5 mg ai/plant

### 190 For the agricultural crop scenarios, transplant rates per acre (or seed rates if transplants

were not ava ilable) were used to estimate the number of plants in a field (USEPA 2011b). Lower estimates were used because this provided the most protective scenario (fewer plants = higher concentration of cyantraniliprole per plant).

Rates were as follows (seeds or transplants per acre): Brassica vegetables = 5445 (cauliflower) Cucurbits = 589 (pumpkin) Fruiting vegetables = 2178 (eggplant and tomato) Leafy vegetables = 6223 (collards) Corm and tuberous vegetables = 5445 (sweet potato, and cassava)

Thus,

Brassica vegetables = (0.4 lb ai/A) / 5445 = 0.00007 lb ai/plant Cucurbits = (0.4 lb ai/A) / 589 = 0.0007 lb ai/plant Fruiting vegetables = (0.4 lb ai/A) / 2178 = 0.0002 lb ai/plant Leafy vegetables = (0.4 lb ai/A) / 6223 = 0.00006 lb ai/plant Corm and tuberous veg etables = (0.4 lb ai/A) / 5445 = 0.00007 lb ai/plant

Conversion to mg

Brassica vegetables = (0.00007 lb ai)*(453592 mg ai/lb) = 32 mg ai/plant Cucurbits = (0.0007 lb ai)*(453592 mg ai/lb) = 318 mg ai/plant Fruiting vegetables = (0.0002 lb ai)*(453592 mg ai/lb) = 91 mg ai/plant Leafy vegetables = (0.00006 lb ai)*(453592 mg ai/lb) = 27 mg ai/plant Corm and tuberous vegetables = (0.00007 lb ai)*(453592 mg ai/lb) = 32 mg ai/plant

It is assumed that the entire application of cyantraniliprole will accumulate i n the plant and that the average weight of a plant is 0.5 kg. Thus, to calculate the dietary concentration (EEC) of cyantraniliprole in a plant, the cyantraniliprole application per plant is divided by its weight (0.5 kg).

Potted ornamental = (2.3 mg ai/ plant) / 0.5 kg = 4.6 mg ai/kg

- plant Potted ornamental = (4.5 mg ai/plant) / 0.5 kg = 9 mg ai/kg

- plant Brassica vegetables = (32 mg ai/plant) / 0.5 kg = 64 mg ai/kg

- plant Cucurbits = (318 mg ai/plant) / 0.5 kg = 636 mg ai/kg

- plant Fruiting vegetables = (91 mg ai/plant) / 0.5 kg = 182 mg ai/kg

- plant Leafy vegetables = (27 mg ai/plant) / 0.5 kg = 54 mg ai/kg

- plant Corm and tuberous vegetables = (32 mg ai/plant) / 0.5 kg = 64 mg ai/kg

- plant

The EECs must be adjusted for mammal body weight. The T

- REX analysis uses three size classes for mammals: 15, 35, and 1000 g. According to the T

- REX User’s Manual, a 15 g mammal consumes 95 percent of its body weight daily, a 35 g mammal consumes 66 percent of its body weight daily, and a 1000 g mammal consumes 15 percen t of its

### 191 body weight daily. Consequently, the general equation for determining the dose of cyantraniliprole received per day is:

EEC mg ai/kg

- bw = (dietary concentration mg ai/kg

- diet)*(body weight consumption kg

diet/kg

- bw)

Potted ornamental 15 g mamma l EEC = (4.6 mg ai/kg

- diet)*(0.95 kg

- diet/kg

- bw) = 4 mg ai/kg

- bw 35 g mammal EEC = (4.6 mg ai/kg

- diet)*(0.66 kg

- diet/kg

- bw) = 3 mg ai/kg

- bw 1000 g mammal EEC = (4.6 mg ai/kg

- diet)*(0.15 kg

- diet/kg

- bw) = 0.7 mg ai/kg

- bw

Potted ornamental 15 g mammal EEC = (9 mg ai/kg

- diet)*(0.95 kg

- diet/kg

- bw) = 9 mg ai/kg

- bw 35 g mammal EEC = (9 mg ai/kg

- diet)*(0.66 kg

- diet/kg

- bw) = 6 mg ai/kg

- bw 1000 g mammal EEC = (9 mg ai/kg

- diet)*(0.15 kg

- diet/kg

- bw) = 1 mg ai/kg

- bw

Brassica vegetables 15 g mammal EEC = (64 mg ai/kg

- diet)*(0.95 kg

- diet/kg

- bw) = 61 mg ai/kg

- bw 35 g mammal EEC = (64 mg ai/kg

- diet)*(0.66 kg

- diet/kg

- bw) = 42 mg ai/kg

- bw 1000 g mammal EEC = (64 mg ai/kg

- diet)*(0.15 kg

- diet/kg

- bw) = 10 mg ai/kg

- bw

Cucurbits 15 g mammal EEC = (636 mg ai/kg

- diet)*(0.95 kg

- diet/kg

- bw) = 604 mg ai/kg

- bw 35 g mammal EEC = (636 mg ai/kg

- diet)*(0.66 kg

- diet/kg

- bw) = 420 mg ai/kg

- bw 1000 g mammal EEC = (636 mg ai/kg

- diet)*(0.15 kg

- diet/kg

- bw) = 95 mg ai/kg

- bw

Fruiting vegetables 15 g mammal EEC = (18 2 mg ai/kg

- diet)*(0.95 kg

- diet/kg

- bw) = 173 mg ai/kg

- bw 35 g mammal EEC = (182 mg ai/kg

- diet)*(0.66 kg

- diet/kg

- bw) = 120 mg ai/kg

- bw 1000 g mammal EEC = (182 mg ai/kg

- diet)*(0.15 kg

- diet/kg

- bw) = 27 mg ai/kg

- bw

Leafy vegetables 15 g mammal EEC = (54 mg ai /kg

- diet)*(0.95 kg

- diet/kg

- bw) = 51 mg ai/kg

- bw 35 g mammal EEC = (54 mg ai/kg

- diet)*(0.66 kg

- diet/kg

- bw) = 36 mg ai/kg

- bw 1000 g mammal EEC = (54 mg ai/kg

- diet)*(0.15 kg

- diet/kg

- bw) = 8 mg ai/kg

- bw

Corm and tuberous vegetables 15 g mammal EEC = (64 mg ai /kg

- diet)*(0.95 kg

- diet/kg

- bw) = 61 mg ai/kg

- bw 35 g mammal EEC = (64 mg ai/kg

- diet)*(0.66 kg

- diet/kg

- bw) = 42 mg ai/kg

- bw 1000 g mammal EEC = (64 mg ai/kg

- diet)*(0.15 kg

- diet/kg

- bw) = 10 mg ai/kg

- bw

### 192 Appendix G SAMPLE TerrPlant Input and Output for the Proposed Cyantraniliprole

TerrPlant v. 1.2.2
Green values signify user inputs (Tables 1, 2 and 4).
Input and output guidance is in popups indicated by red arrows.

Table 1. Chemical Identity.

Chemical Name Cyantraniliprole

PC code 90098

Use
Application Method

Application Form Liquid
Solubility in Water (ppm) 14.2

Table 2. Input parameters used to derive EECs.

Input Parameter Symbol Value Units

Application Rate A 0.13 y

Incorporation I 1 none

Runoff Fraction R 0.02 none

Drift Fraction D 0.01 none

Table 3. EECs for Cyantraniliprole. Units in y.

Description Equation EEC

Runoff to dry areas (A/I)*R 0.0026

Runoff to semi

- aquatic areas (A/I)*R*10 0.026
Spray drift A*D 0.0013
Total for dry areas ((A/I)*R)+(A*D) 0.0039

Total for semi

- aquatic areas ((A/I)*R*10)+(A*D) 0.0273

TerrPlant v. 1.2.2
Green values signify user inputs (Tables 1, 2 and 4).
Input and output guidance is in popups indicated by red arrows.

Table 1. Chemical Identity.

Chemical Name Cyantraniliprole

PC code 90098

Use

Application Method

Application Form Liquid
Solubility in Water (ppm) 14.2

Table 2. Input parameters used to derive EECs.

Input Parameter Symbol Value Units

Application Rate A 0.13 y

Incorporation I 1 none

Runoff Fraction R 0.02 none

### 193 Drift Fraction D 0.01 none

Table 3. EECs for Cyantraniliprole. Units in y.

Description Equation EEC

Runoff to dry areas (A/I)*R 0.0026

Runoff to semi

- aquatic areas (A/I)*R*10 0.026
Spray drift A*D 0.0013
Total for dry areas ((A/I)*R)+(A*D) 0.0039

Total for semi

- aquatic areas ((A/I)*R*10)+(A*D) 0.0273

Table 4. Plant survival and growth data used for RQ derivation. Units are in y.

Seedling Emergence Vegetative Vigor

Plant type EC25 NOAEC EC25 NOAEC

Monocot x 0.134 x 0.067

Dicot x 0.134 x 0.134

Table 5. RQ values for plants in dry and semi

- aquatic areas exposed to Cyantraniliprole through runoff and/or spray drift.*

Plant Type Listed Status Dry Semi

- Aquatic Spray Drift

Monocot non

- listed N/A N/A N/A

Monocot listed <0.1 0.20 <0.1

Dicot non

- listed N/A N/A N/A

Dicot listed <0.1 0.20 <0.1

*If RQ > 1.0, the LOC is exceeded, resulting in potential for risk to that plant group.

### 194 Appendix H Agency Levels of Concern (LOC)

Risk Description RQ Taxa

Acute Potential for acute risk to non

- target organisms which may warrant regulatory action in addition

to restricted use classification acute RQ > 0.5 aquatic animals, mammals, birds

Acute Restricted

Use Potential for acute risk to non

- target organisms, but may be mitigated through restricted use

classification acute RQ > 0.1 aquatic animals

acute RQ > 0.2 mammals and

birds

Acute Listed Species Listed species may be potentially affected by

use acute RQ > 0.05 aquatic animals

acute RQ > 0.1 mammals and

birds

Chronic Potential for chronic risk may warrant regulatory action, listed species may potentially

be affected through chronic exposure chronic RQ > 1 all animals

Non

- Listed and

Listed Plant Potential for effects in non

- listed and listed plants RQ > 1 all plants

### 195 Appendix I LOCATES Endangered Species List

Based on the following crops: almonds, apples, apricots, artichokes, beets, bittermelon, blueberries, broccoli, Brussels sprouts, Chinese cabbage, head cabbage, mustard cabbage, cantaloupe, canola, cassava, cauliflower, celery, cherries, chestnut, Christm as trees, citron, citrus, collards, cotton, crambe, cucumbers and pickles, currants, eggplant, endive and escarole, garlic, grapefruit, hazelnuts, honeydew melon, jojoba harvest, kale, kumquats, lemons, lemons and limes, lettuce, limes, macadamia nuts, mus kmelons and pepinos, mustard greens, mustard seed, nectarines, nuts, okra, onions, oranges, orchards, peaches, pears, pecans, peppers, persimmons, pistachios, plums and prunes, pluots, potatoes, pumpkins, rapeseed, rhubarb, sesame, sod harvested, spinach, squash, sunflower seed, sweet potatoes, tangelos, tangerines, tomatoes, walnuts, watermelons, woodlands, and yams.

INVNAME SCINAME Status STATE

NAME Taxon

Salamander, Frosted

Flatwoods Ambystoma cingulatum T Alabama Amphibian

Salamander, Red Hills Phaeognathus hubrichti T Alabama Amphibian

Stork, Wood Mycteria americana E Alabama Bird

Tern, Interior (population) Least Sterna antillarum E Alabama Bird

Woodpecker, Red

cockaded Picoides borealis E Alabama Bird

Plover, Piping Charadrius melodus E/T Alabama Bird

Alabama pearlshell Margaritifera marrianae E Alabama Bivalve

Choctaw Bean Villosa choctawensis E Alabama Bivalve

Combshell, Southern (=Penitent mussel) Epioblasma penita E Alabama Bivalve

Combshell, Upland Epioblasma metastriata E Alabama Bivalve

Fanshell Cyprogenia stegaria E Alabama Bivalve

Kidneyshell, Triangular Ptychobranchus greenii E Alabama Bivalve

Mucket, Pink (Pearlymussel) Lampsilis abrupta E Alabama Bivalve

Mussel, Acornshell

Southern Epioblasma othcaloogensis E Alabama Bivalve

Mussel, Coosa

Moccasinshell Medionidus parvulus E Alabama Bivalve

### 196 INVNAME SCINAME Status STATE

NAME Taxon

Mussel, Cumberland

Combshell Epioblasma brevidens E Alabama Bivalve

Mussel, Dark Pigtoe Pleurobema furvum E Alabama Bivalve

Mussel, Fine

- rayed Pigtoe Fusconaia cuneolus E Alabama Bivalve

Mussel, Flat Pigtoe (=Marshall's Mussel) Pleurobema marshalli E Alabama Bivalve

Mussel, Georgia pigtoe Pleurobema hanleyianum E Alabama Bivalve

Mussel, Gulf

Moccasinshell Medionidus penicillatus E Alabama Bivalve

Mussel, Heavy Pigtoe (=Judge Tait's Mussel) Pleurobema taitianum E Alabama Bivalve

Mussel, Oval Pigtoe Pleurobema pyriforme E Alabama Bivalve

Mussel, Ovate

Clubshell Pleurobema perovatum E Alabama Bivalve

Mussel, Ring Pink (=Golf Stick Pearly) Obovaria retusa E Alabama Bivalve

Mussel, Rough Pigtoe Pleurobema plenum E Alabama Bivalve

Mussel, Shiny Pigtoe Fusconaia cor E Alabama Bivalve

Mussel, Shiny

- rayed

Pocketbook Lampsilis subangulata E Alabama Bivalve

Mussel, snuffbox Epioblasma triquetra E Alabama Bivalve

Mussel, Southern

Clubshell Pleurobema decisum E Alabama Bivalve

Mussel, Southern Pigtoe Pleurobema georgianum E Alabama Bivalve

Pearlymussel, Alabama Lamp Lampsilis virescens E Alabama Bivalve

Pearlymussel, Cracking Hemistena lata E Alabama Bivalve

Pearlymussel,

Cumberland Monkeyface Quadrula intermedia E Alabama Bivalve

### 197 INVNAME SCINAME Status STATE

NAME Taxon

Pearlymussel, Orange

footed Plethobasus cooperianus E Alabama Bivalve

Pearlymussel, Pale Lilliput Toxolasma cylindrellus E Alabama Bivalve

Pearlymussel, Turgid

blossom Epioblasma turgidula E Alabama Bivalve

Pearlymussel, White Wartyback Plethobasus cicatricosus E Alabama Bivalve

Round Ebonyshell Fusconaia rotulata E Alabama Bivalve

Sheepnose mussel Plethobasus cyphyus E Alabama Bivalve

Southern Kidneyshell Ptychobranchus jonesi E Alabama Bivalve

Spectaclecase mussel Cumberlandia monodonta E Alabama Bivalve

Stirrupshell Quadrula stapes E Alabama Bivalve

Bankclimber, Purple Elliptoideus sloatianus T Alabama Bivalve

fuzzy pigtoe Pleurobema strodeanum T Alabama Bivalve

Mucket, Orange

- nacre Lampsilis perovalis T Alabama Bivalve

Mussel, Alabama

Moccasinshell Medionidus acutissimus T Alabama Bivalve

Mussel, Fine

- lined

Pocketbook Lampsilis altilis T Alabama Bivalve

Mussel, Heelsplitter

Inflated Potamilus inflatus T Alabama Bivalve

Narrow Pigtoe Fusconaia escambia T Alabama Bivalve

Southern Sandshell Hamiota australis T Alabama Bivalve

Tapered Pigtoe Fusconaia burkei T Alabama Bivalve

Shrimp, Alabama

Cave Palaemonias alabamae E Alabama Crustacean

Chaffseed, American Schwalbea americana E Alabama Dicot

Clover, Leafy Prairie Dalea foliosa E Alabama Dicot

Harperella Ptilimnium nodosum E Alabama Dicot

Leather

- flower,

Alabama Clematis socialis E Alabama Dicot

### 198 INVNAME SCINAME Status STATE

NAME Taxon

Leather

- flower,

Morefield's Clematis morefieldii E Alabama Dicot

Pinkroot, Gentian Spigelia gentianoides E Alabama Dicot

Pitcher

- plant, Alabama

Canebrake Sarracenia rubra

alabamensis E Alabama Dicot

Pitcher

- plant, Green Sarracenia oreophila E Alabama Dicot

Pondberry Lindera melissifolia E Alabama Dicot

Amphianthus, Little Amphianthus pusillus T Alabama Dicot

Barbara Buttons,

Mohr's Marshallia mohrii T Alabama Dicot

Bladderpod, Lyrate Lesquerella lyrata T Alabama Dicot

Potato

- bean, Price's Apios priceana T Alabama Dicot

Quillwort, Louisiana Isoetes louisianensis E Alabama Ferns

Fern, Alabama Streak

sorus Thelypteris pilosa var.

alabamensis T Alabama Ferns

Fern, American hart's

tongue Asplenium scolopendrium

var. americanum T Alabama Ferns

Cavefish, Alabama Speoplatyrhinus poulsoni E Alabama Fish

Darter, Boulder Etheostoma wapiti E Alabama Fish

Darter, Vermilion Etheostoma chermocki E Alabama Fish

Darter, Watercress Etheostoma nuchale E Alabama Fish

Rush darter Etheostoma phytophilum E Alabama Fish

Shiner, Cahaba Notropis cahabae E Alabama Fish

Shiner, Palezone Notropis albizonatus E Alabama Fish

Sturgeon, Alabama Scaphirhynchus suttkusi E Alabama Fish

Chub, Spotfin Erimonax monachus T Alabama Fish

Darter, Goldline Percina aurolineata T Alabama Fish

Darter, Slackwater Etheostoma boschungi T Alabama Fish

Darter, Snail Percina tanasi T Alabama Fish

### 199 INVNAME SCINAME Status STATE

NAME Taxon

Sculpin, Pygmy Cottus paulus (=pygmaeus) T Alabama Fish

Shiner, Blue Cyprinella caerulea T Alabama Fish

Sturgeon, Gulf Acipenser oxyrinchus

desotoi T Alabama Fish

Campeloma, Slender Campeloma decampi E Alabama Gastropod

Hornsnail, rough Pleurocera foremani E Alabama Gastropod

Pebblesnail, Flat Lepyrium showalteri E Alabama Gastropod

Riversnail, Anthony's Athearnia anthonyi E Alabama Gastropod

Rocksnail, interrupted Leptoxis foremani E Alabama Gastropod

Rocksnail, Plicate Leptoxis plicata E Alabama Gastropod

Snail, Armored Pyrgulopsis (=Marstonia) pachyta E Alabama Gastropod

Snail, Lioplax Cylindrical Lioplax cyclostomaformis E Alabama Gastropod

Elimia, Lacy Elimia crenatella T Alabama Gastropod

Rocksnail, Painted Leptoxis taeniata T Alabama Gastropod

Rocksnail, Round Leptoxis ampla T Alabama Gastropod

Snail, Tulotoma Tulotoma magnifica T Alabama Gastropod

Butterfly, Mitchell's Satyr Neonympha mitchellii

mitchellii E Alabama Insect

Dragonfly, Hine's

Emerald Somatochlora hineana E Alabama Insect

Bat, Gray Myotis grisescens E Alabama Mammal

Bat, Indiana Myotis sodalis E Alabama Mammal

Manatee, West Indian Trichechus manatus E Alabama Mammal

Mouse, Alabama

Beach Peromyscus polionotus

ammobates E Alabama Mammal

Mouse, Perdido Key

Beach Peromyscus polionotus trissyllepsis E Alabama Mammal

Whale, Blue Balaenoptera musculus E Alabama Mammal

### 200 INVNAME SCINAME Status STATE

NAME Taxon

Bulrush, Northeastern (=Barbed Bristle) Scirpus ancistrochaetus E Alabama Monocot

Grass, Tennessee

Yellow

- eyed Xyris tennesseensis E Alabama Monocot

Trillium, Relict Trillium reliquum E Alabama Monocot

Water

- plantain, Kral's Sagittaria secundifolia T Alabama Monocot

Sea turtle, hawksbill Eretmochelys imbricata E Alabama Reptile

Sea turtle, Kemp's ridley Lepidochelys kempii E Alabama Reptile

Sea turtle, leatherback Dermochelys coriacea E Alabama Reptile

Turtle, Alabama Red

bellied Pseudemys alabamensis E Alabama Reptile

Sea turtle, green Chelonia mydas E/T Alabama Reptile

Sea turtle, loggerhead Caretta caretta E/T Alabama Reptile

Snake, Eastern Indigo Drymarchon corais couperi T Alabama Reptile

Tortoise, Gopher Gopherus polyphemus T Alabama Reptile

Turtle, Flattened Musk Sternotherus depressus T Alabama Reptile

Albatross, Short

- tailed Phoebastria (=Diomedea)

albatrus E Alaska Bird

Curlew, Eskimo Numenius borealis E Alaska Bird

Eider, Steller's Polysticta stelleri T Alaska Bird

Bison, Wood Bison bison athabascae E Alaska Mammal

Whale, beluga Delphinapterus leucas E Alaska Mammal

Whale, Blue Balaenoptera musculus E Alaska Mammal

Whale, Bowhead Balaena mysticetus E Alaska Mammal

Whale, Finback Balaenoptera physalus E Alaska Mammal

Whale, Gray Eschrichtius robustus E Alaska Mammal

### 201 INVNAME SCINAME Status STATE

NAME Taxon

Whale, Humpback Megaptera novaeangliae E Alaska Mammal

Whale, North Pacific right Eubalaena japonica E Alaska Mammal

Whale, Sei Balaenoptera borealis E Alaska Mammal

Whale, Sperm Physeter catodon (=macrocephalus) E Alaska Mammal

Sea

- lion, Steller Eumetopias jubatus E/T Alaska Mammal

Otter, Northern Sea Enhydra lutris kenyoni T Alaska Mammal

Seal, spotted Phoca largha T Alaska Mammal

Sea turtle, leatherback Dermochelys coriacea E Alaska Reptile

Salamander, Sonora Tiger Ambystoma tigrinum

stebbinsi E Arizona Amphibian

Frog, Chiricahua Leopard Rana chiricahuensis T Arizona Amphibian

Bobwhite, Masked Colinus virginianus ridgwayi E Arizona Bird

Condor, California Gymnogyps californianus E Arizona Bird

Falcon, Northern Aplomado Falco femoralis septentrionalis E Arizona Bird

Flycatcher,

Southwestern Willow Empidonax traillii extimus E Arizona Bird

Rail, Yuma Clapper Rallus longirostris yumanensis E Arizona Bird

Owl, Mexican Spotted Strix occidentalis lucida T Arizona Bird

Blue

- star, Kearney's Amsonia kearneyana E Arizona Dicot

Cactus, Arizona Hedgehog Echinocereus triglochidiatus

var. arizonicus E Arizona Dicot

Cactus, Brady

Pincushion Pediocactus bradyi E Arizona Dicot

Cactus, Nichol's Turk's

Head Echinocactus
horizonthalonius var.

nicholii E Arizona Dicot

### 202 INVNAME SCINAME Status STATE

NAME Taxon

Cactus, Peebles Navajo Pediocactus peeblesianus peeblesianus E Arizona Dicot

Cactus, Pima Pineapple Coryphantha scheeri var. robustispina E Arizona Dicot

Cliffrose, Arizona Purshia (=cowania) subintegra E Arizona Dicot

Milk

- vetch, Holmgren Astragalus holmgreniorum E Arizona Dicot

Milk

- vetch, Sentry Astragalus cremnophylax var. cremnophylax E Arizona Dicot

Umbel, Huachuca

Water Lilaeopsis schaffneriana

var. recurva E Arizona Dicot

Cactus, Cochise

Pincushion Coryphantha robbinsorum T Arizona Dicot

Cactus, Siler

Pincushion Pediocactus (=Echinocactus,=Utahia)

sileri T Arizona Dicot

Cycladenia, Jones Cycladenia jonesii (=humilis) T Arizona Dicot

Fleabane, Zuni Erigeron rhizomatus T Arizona Dicot

Groundsel, San

Francisco Peaks Senecio franciscanus T Arizona Dicot

Milkweed, Welsh's Asclepias welshii T Arizona Dicot

Chub, Bonytail Gila elegans E Arizona Fish

Chub, Gila Gila intermedia E Arizona Fish

Chub, Humpback Gila cypha E Arizona Fish

Chub, Virgin River Gila seminuda (=robusta) E Arizona Fish

Chub, Yaqui Gila purpurea E Arizona Fish

Minnow, Loach Tiaroga cobitis E Arizona Fish

Pupfish, Desert Cyprinodon macularius E Arizona Fish

Spikedace Meda fulgida E Arizona Fish

Squawfish, Colorado Ptychocheilus lucius E Arizona Fish

Sucker, Razorback Xyrauchen texanus E Arizona Fish

### 203 INVNAME SCINAME Status STATE

NAME Taxon

Topminnow, Gila (Yaqui) Poeciliopsis occidentalis E Arizona Fish

Trout, Gila Oncorhynchus gilae E Arizona Fish

Woundfin Plagopterus argentissimus E Arizona Fish

Steelhead Oncorhynchus (=Salmo) mykiss E/T Arizona Fish

Catfish, Yaqui Ictalurus pricei T Arizona Fish

Chub, Sonora Gila ditaenia T Arizona Fish

Shiner, Beautiful Cyprinella formosa T Arizona Fish

Spinedace, Little

Colorado Lepidomeda vittata T Arizona Fish

Trout, Apache Oncorhynchus apache T Arizona Fish

Ambersnail, Kanab Oxyloma haydeni

kanabensis E Arizona Gastropod

Springsnail, San

Bernardino Pyrgulopsis bernardina E Arizona Gastropod

Springsnail, Three

Forks Pyrgulopsis trivialis E Arizona Gastropod

Bat, Lesser (=Sanborn's) Long

nosed Leptonycteris curasoae yerbabuenae E Arizona Mammal

Ferret, Black

- footed Mustela nigripes E Arizona Mammal

Jaguar Panthera onca E Arizona Mammal

Jaguarundi, Sinaloan Herpailurus (=Felis) yagouaroundi tolteca E Arizona Mammal

Ocelot Leopardus (=Felis) pardalis E Arizona Mammal

Pronghorn, Sonoran Antilocapra americana

sonoriensis E Arizona Mammal

Squirrel, Mount

Graham Red Tamiasciurus hudsonicus grahamensis E Arizona Mammal

Vole, Hualapai

Mexican Microtus mexicanus hualpaiensis E Arizona Mammal

Ladies'

- tresses, Canelo

Hills Spiranthes delitescens E Arizona Monocot

### 204 INVNAME SCINAME Status STATE

NAME Taxon

Sedge, Navajo Carex specuicola T Arizona Monocot

Rattlesnake, New Mexican Ridge

- nosed Crotalus willardi obscurus T Arizona Reptile

Tortoise, Desert Gopherus agassizii T Arizona Reptile

Ozark Hellbender Cryptobranchus alleganiensis bishopi E Arkansas Amphibian

Tern, Interior (population) Least Sterna antillarum E Arkansas Bird

Warbler, Bachman's Vermivora bachmanii E Arkansas Bird

Woodpecker, Ivory

billed Campephilus principalis E Arkansas Bird

Woodpecker, Red

cockaded Picoides borealis E Arkansas Bird

Mucket, Pink (Pearlymussel) Lampsilis abrupta E Arkansas Bivalve

Mussel, Scaleshell Leptodea leptodon E Arkansas Bivalve

Mussel, snuffbox Epioblasma triquetra E Arkansas Bivalve

Mussel, Speckled

Pocketbook Lampsilis streckeri E Arkansas Bivalve

Mussel, Winged Mapleleaf Quadrula fragosa E Arkansas Bivalve

Pearlymussel, Curtis' Epioblasma florentina

curtisii E Arkansas Bivalve

Pearlymussel, Fat

Pocketbook Potamilus capax E Arkansas Bivalve

Pearlymussel, Turgid

blossom Epioblasma turgidula E Arkansas Bivalve

Rock

- pocketbook, Ouachita (=Wheeler's pm) Arkansia wheeleri E Arkansas Bivalve

Spectaclecase mussel Cumberlandia monodonta E Arkansas Bivalve

Fatmucket, Arkansas Lampsilis powelli T Arkansas Bivalve

Crayfish, Cave (Cambarus aculabrum) Cambarus aculabrum E Arkansas Crustacean

### 205 INVNAME SCINAME Status STATE

NAME Taxon

Crayfish, Cave (Cambarus zophonastes) Cambarus zophonastes E Arkansas Crustacean

Clover, Running

Buffalo Trifolium stoloniferum E Arkansas Dicot

Harperella Ptilimnium nodosum E Arkansas Dicot

Pondberry Lindera melissifolia E Arkansas Dicot

Bladderpod, Missouri Lesquerella filiformis T Arkansas Dicot

Catchfly, Spalding's Silene spaldingii T Arkansas Dicot

Fruit, Earth (=geocarpon) Geocarpon minimum T Arkansas Dicot

Sturgeon, Pallid Scaphirhynchus albus E Arkansas Fish

Yellowcheek darter Etheostoma moorei E Arkansas Fish

Cavefish, Ozark Amblyopsis rosae T Arkansas Fish

Darter, Leopard Percina pantherina T Arkansas Fish

Shiner, Arkansas River Notropis girardi T Arkansas Fish

Trout, Bull Salvelinus confluentus T Arkansas Fish

Shagreen, Magazine

Mountain Mesodon magazinensis T Arkansas Gastropod

Beetle, American Burying Nicrophorus americanus E Arkansas Insect

Bat, Gray Myotis grisescens E Arkansas Mammal

Bat, Indiana Myotis sodalis E Arkansas Mammal

Bat, Ozark Big

- eared Corynorhinus (=Plecotus) townsendii ingens E Arkansas Mammal

Panther, Florida Puma (=Felis) concolor coryi E Arkansas Mammal

Rabbit, Pygmy Brachylagus idahoensis E Arkansas Mammal

Ladies'

- tresses, Ute Spiranthes diluvialis T Arkansas Monocot

Frog, Mountain

Yellow

- legged Rana muscosa E California Amphibian

Salamander, California Tiger Ambystoma californiense E California Amphibian

### 206 INVNAME SCINAME Status STATE

NAME Taxon

Salamander, Desert

Slender Batrachoseps aridus E California Amphibian

Salamander, Santa Cruz Long

- toed Ambystoma macrodactylum

croceum E California Amphibian

Toad, Arroyo

Southwestern Bufo californicus (=microscaphus) E California Amphibian

Frog, California Red

legged Rana aurora draytonii T California Amphibian

Albatross, Short

- tailed Phoebastria (=Diomedea)

albatrus E California Bird

Condor, California Gymnogyps californianus E California Bird

Flycatcher,

Southwestern Willow Empidonax traillii extimus E California Bird

Rail, California Clapper Rallus longirostris obsoletus E California Bird

Rail, Light

- footed Clapper Rallus longirostris levipes E California Bird

Rail, Yuma Clapper Rallus longirostris yumanensis E California Bird

Shrike, San Clemente Loggerhead Lanius ludovicianus mearnsi E California Bird

Tern, California Least Sterna antillarum browni E California Bird

Vireo, Least Bell's Vireo bellii pusillus E California Bird

Gnatcatcher, Coastal

California Polioptila californica californica T California Bird

Murrelet, Marbled Brachyramphus marmoratus T California Bird

Owl, Northern Spotted Strix occidentalis caurina T California Bird

Plover, Western Snowy Charadrius alexandrinus

nivosus T California Bird

Sparrow, San Clemente Sage Amphispiza belli clementeae T California Bird

### 207 INVNAME SCINAME Status STATE

NAME Taxon

Towhee, Inyo Brown Pipilo crissalis eremophilus T California Bird

Cypress, Santa Cruz Cupressus abramsiana E California Conf/cycds

Cypress, Gowen Cupressus goveniana ssp. goveniana T California Conf/cycds

Crayfish, Shasta Pacifastacus fortis E California Crustacean

Fairy Shrimp, Conservancy Fairy Branchinecta conservatio E California Crustacean

Fairy Shrimp, Longhorn Branchinecta longiantenna E California Crustacean

Fairy Shrimp,

Riverside Streptocephalus woottoni E California Crustacean

Fairy Shrimp, San Diego Branchinecta sandiegonensis E California Crustacean

Shrimp, California

Freshwater Syncaris pacifica E California Crustacean

Tadpole Shrimp,

Vernal Pool Lepidurus packardi E California Crustacean

Fairy Shrimp, Vernal

Pool Branchinecta lynchi T California Crustacean

Allocarya, Calistoga Plagiobothrys strictus E California Dicot

Ambrosia, San Diego Ambrosia pumila E California Dicot

Barberry, Island Berberis pinnata ssp.

insularis E California Dicot

Barberry, Nevin's Berberis nevinii E California Dicot

Bedstraw, El Dorado Galium californicum ssp.

sierrae E California Dicot

Bedstraw, Island Galium buxifolium E California Dicot

Bird's

- beak, Palmate

bracted Cordylanthus palmatus E California Dicot

Bird's

- beak, Pennell's Cordylanthus tenuis ssp. capillaris E California Dicot

Bird's

- beak, salt marsh Cordylanthus maritimus ssp.

maritimus E California Dicot

Bird's

- beak, Soft Cordylanthus mollis ssp.

mollis E California Dicot

### 208 INVNAME SCINAME Status STATE

NAME Taxon

Bladderpod, San

Bernardino Mountains Lesquerella kingii ssp.

bernardina E California Dicot

Broom, San Clemente

Island Lotus dendroideus ssp.

traskiae E California Dicot

Buckwheat, Cushenbury Eriogonum ovalifolium var.

vineum E California Dicot

Buckwheat, Ione (incl. Irish Hill) Eriogonum apricum (incl. var. prostratum) E California Dicot

Bush

- mallow, San

Clemente Island Malacothamnus clementinus E California Dicot

Bush

- mallow, Santa

Cruz Island Malacothamnus fasciculatus

var. nesioticus E California Dicot

Button

- celery, San Diego Eryngium aristulatum var. parishii E California Dicot

Cactus, Bakersfield Opuntia treleasei E California Dicot

Ceanothus, Coyote Ceanothus ferrisae E California Dicot

Ceanothus, Pine Hill Ceanothus roderickii E California Dicot

Checker

- mallow,

Keck's Sidalcea keckii E California Dicot

Checker

- mallow,

Kenwood Marsh Sidalcea oregana ssp. valida E California Dicot

Checker

- mallow,

Pedate Sidalcea pedata E California Dicot

Clarkia, Pismo Clarkia speciosa ssp.

immaculata E California Dicot

Clarkia, Presidio Clarkia franciscana E California Dicot

Clarkia, Vine Hill Clarkia imbricata E California Dicot

Clover, Monterey Trifolium trichocalyx E California Dicot

Clover, Showy Indian Trifolium amoenum E California Dicot

Coyote

- thistle, Loch

Lomond Eryngium constancei E California Dicot

Crownscale, San Jacinto Valley Atriplex coronata var.

notatior E California Dicot

### 209 INVNAME SCINAME Status STATE

NAME Taxon

Dudleya, Santa Clara Valley Dudleya setchellii E California Dicot

Evening

- primrose,

Antioch Dunes Oenothera deltoides ssp.

howellii E California Dicot

Evening

- primrose, Eureka Valley Oenothera avita ssp.

eurekensis E California Dicot

Fiddleneck, Large

flowered Amsinckia grandiflora E California Dicot

Flannelbush, Mexican Fremontodendron

mexicanum E California Dicot

Flannelbush, Pine Hill Fremontodendron californicum ssp. decumbens E California Dicot

Fringepod, Santa Cruz

Island Thysanocarpus conchuliferus E California Dicot

Gilia, Hoffmann's

Slender

- flowered Gilia tenuiflora ssp. hoffmannii E California Dicot

Gilia, Monterey Gilia tenuiflora ssp.

arenaria E California Dicot

Golden Sunburst, Hartweg's Pseudobahia bahiifolia E California Dicot

Goldfields, Burke's Lasthenia burkei E California Dicot

Goldfields, Contra

Costa Lasthenia conjugens E California Dicot

Grass, Hairy Orcutt Orcuttia pilosa E California Dicot

Grass, Sacramento

Orcutt Orcuttia viscida E California Dicot

Jewelflower,

California Caulanthus californicus E California Dicot

Jewelflower, Metcalf Canyon Streptanthus albidus ssp.

albidus E California Dicot

Jewelflower, Tiburon Streptanthus niger E California Dicot

Larkspur, Baker's Delphinium bakeri E California Dicot

Larkspur, San

Clemente Island Delphinium variegatum ssp.

kinkiense E California Dicot

Larkspur, Yellow Delphinium luteum E California Dicot

Layia, Beach Layia carnosa E California Dicot

### 210 INVNAME SCINAME Status STATE

NAME Taxon

Lessingia, San

Francisco Lessingia germanorum (=L.g. var. germanorum) E California Dicot

Liveforever, Santa

Barbara Island Dudleya traskiae E California Dicot

Lupine, Clover Lupinus tidestromii E California Dicot

Lupine, Nipomo Mesa Lupinus nipomensis E California Dicot

Malacothrix, Island Malacothrix squalida E California Dicot

Malacothrix, Santa

Cruz Island Malacothrix indecora E California Dicot

Mallow, Kern Eremalche kernensis E California Dicot

Manzanita, Del Mar Arctostaphylos glandulosa ssp. crassifolia E California Dicot

Manzanita, Santa Rosa

Island Arctostaphylos confertiflora E California Dicot

Meadowfoam, Butte County Limnanthes floccosa ssp. californica E California Dicot

Meadowfoam, Sebastopol Limnanthes vinculans E California Dicot

Milk

- vetch, Applegate's Astragalus applegatei E California Dicot

Milk

- vetch, Braunton's Astragalus brauntonii E California Dicot

Milk

- vetch, Clara

Hunt's Astragalus clarianus E California Dicot

Milk

- vetch, Coachella Valley Astragalus lentiginosus var.

coachellae E California Dicot

Milk

- vetch, Coastal

Dunes Astragalus tener var. titi E California Dicot

Milk

- vetch, Cushenbury Astragalus albens E California Dicot

Milk

- vetch, Lane

Mountain Astragalus jaegerianus E California Dicot

Milk

- vetch, Triple

ribbed Astragalus tricarinatus E California Dicot

### 211 INVNAME SCINAME Status STATE

NAME Taxon

Milk

- vetch, Ventura

Marsh Astragalus pycnostachyus

var. lanosissimus E California Dicot

Mint, Otay Mesa Pogogyne nudiuscula E California Dicot

Mint, San Diego Mesa Pogogyne abramsii E California Dicot

Monardella, Willowy Monardella linoides ssp.

viminea E California Dicot

Morning

- glory,

Stebbins Calystegia stebbinsii E California Dicot

Mountainbalm, Indian

Knob Eriodictyon altissimum E California Dicot

Mountain

- mahogany,

Catalina Island Cercocarpus traskiae E California Dicot

Mustard, Slender

petaled Thelypodium stenopetalum E California Dicot

Navarretia, Few

flowered Navarretia leucocephala ssp. Pauciflora E California Dicot

Navarretia, Many

flowered Navarretia leucocephala ssp. plieantha E California Dicot

Niterwort, Amargosa Nitrophila mohavensis E California Dicot

Oxytheca, Cushenbury Oxytheca parishii var. goodmaniana E California Dicot

Paintbrush, San

Clemente Island Indian Castilleja grisea E California Dicot

Paintbrush, Soft

leaved Castilleja mollis E California Dicot

Paintbrush, Tiburon Castilleja affinis ssp. neglecta E California Dicot

Penny

- cress, Kneeland

Prairie Thlaspi californicum E California Dicot

Pentachaeta, Lyon's Pentachaeta lyonii E California Dicot

Pentachaeta, White

rayed Pentachaeta bellidiflora E California Dicot

### 212 INVNAME SCINAME Status STATE

NAME Taxon

Phacelia, Island Phacelia insularis ssp.

insularis E California Dicot

Phlox, Yreka Phlox hirsuta E California Dicot

Polygonum, Scott's Valley Polygonum hickmanii E California Dicot

Potentilla, Hickman's Potentilla hickmanii E California Dicot

Rock

- cress, Hoffmann's Arabis hoffmannii E California Dicot

Rock

- cress, McDonald's Arabis mcdonaldiana E California Dicot

Rock

- cress, Santa

Cruz Island Sibara filifolia E California Dicot

San Francisco

manzanita Arctostaphylos franciscana E California Dicot

Sandwort, Marsh Arenaria paludicola E California Dicot

Sea

- blite, California Suaeda californica E California Dicot

Spineflower, Ben

Lomond Chorizanthe pungens var. hartwegiana E California Dicot

Spineflower, Howell's Chorizanthe howellii E California Dicot

Spineflower, Orcutt's Chorizanthe orcuttiana E California Dicot

Spineflower, Robust Chorizanthe robusta va r.

robusta E California Dicot

Spineflower, Scotts Valley Chorizanthe robusta var. hartwegii E California Dicot

Spineflower, Slender

horned Dodecahema leptoceras E California Dicot

Spineflower, Sonoma Chorizanthe valida E California Dicot

Stickyseed, Baker's Blennosperma bakeri E California Dicot

Stonecrop, Lake County Parvisedum leiocarpum E California Dicot

Sunflower, San Mateo Woolly Eriophyllum latilobum E California Dicot

Taraxacum, California Taraxacum californicum E California Dicot

### 213 INVNAME SCINAME Status STATE

NAME Taxon

Tarplant, Gaviota Deinandra increscens ssp.

villosa E California Dicot

Thistle, Chorro creek Bog Cirsium fontinale var. obispoense E California Dicot

Thistle, Fountain Cirsium fontinale var. fontinale E California Dicot

Thistle, La Graciosa Cirsium loncholepis E California Dicot

Thistle, Suisun Cirsium hydrophilum var. hydrophilum E California Dicot

Thornmint, San Mateo Acanthomintha obovata ssp.

duttonii E California Dicot

Tuctoria, Green's Tuctoria greenei E California Dicot

Wallflower, Ben

Lomond Erysimum teretifolium E California Dicot

Wallflower, Contra

Costa Erysimum capitatum var.

angustatum E California Dicot

Wallflower, Menzie's Erysimum menziesii E California Dicot

Watercress, Gambel's Rorippa gambellii E California Dicot

Woodland

- star, San

Clemente Island Lithophragma maximum E California Dicot

Woolly

- star, Santa

Ana River Eriastrum densifolium ssp.

sanctorum E California Dicot

Woolly

- threads, San Joaquin Monolopia (=Lembertia) congdonii E California Dicot

Yerba Santa, Lompoc Eriodictyon capitatum E California Dicot

Adobe Sunburst, San Joaquin Pseudobahia peirsonii T California Dicot

Baccharis, Encinitas Baccharis vanessae T California Dicot

Bluecurls, Hidden

Lake Trichostema

austromontanum ssp.
compactum T California Dicot

Buckwheat, Southern

Mountain Wild Eriogonum kennedyi var.

austromontanum T California Dicot

### 214 INVNAME SCINAME Status STATE

NAME Taxon

Butterweed, Layne's Senecio layneae T California Dicot

Ceanothus, Vail Lake Ceanothus ophiochilus T California Dicot

Centaury, Spring

loving Centaurium namophilum T California Dicot

Clarkia, Springville Clarkia springvillensis T California Dicot

Clover, Fleshy Owl's Castilleja campestris ssp.

succulenta T California Dicot

Crownbeard, Big

leaved Verbesina dissita T California Dicot

Daisy, Parish's Erigeron parishii T California Dicot

Dudleya, Conejo Dudleya abramsii ssp. parva T California Dicot

Dudleya, Marcescent Dudleya cymosa ssp.

marcescens T California Dicot

Dudleya, Santa Cruz

Island Dudleya nesiotica T California Dicot

Dudleya, Santa

Monica Mountains Dudleya cymosa ssp. ovatifolia T California Dicot

Dudleya, Verity's Dudleya verityi T California Dicot

Dwarf

- flax, Marin Hesperolinon congestum T California Dicot

Evening

- primrose, San

Benito Camissonia benitensis T California Dicot

Grass, Slender Orcutt Orcuttia tenuis T California Dicot

Gumplant, Ash

Meadows Grindelia fraxino

- pratensis T California Dicot

Howellia, Water Howellia aquatilis T California Dicot

Liveforever, Laguna

Beach Dudleya stolonifera T California Dicot

Manzanita, Ione Arctostaphylos myrtifolia T California Dicot

Manzanita, Morro Arctostaphylos morroensis T California Dicot

Manzanita, Pallid Arctostaphylos pallida T California Dicot

### 215 INVNAME SCINAME Status STATE

NAME Taxon

Milk

- vetch, Fish Slough Astragalus lentiginosus var. piscinensis T California Dicot

Milk

- vetch, Pierson's Astragalus magdalenae var. peirsonii T California Dicot

Navarretia, Spreading Navarretia fossalis T California Dicot

Paintbrush, Ash

- grey Indian Castilleja cinerea T California Dicot

Pussypaws, Mariposa Calyptridium pulchellum T California Dicot

Rush

- rose, Island Helianthemum greenei T California Dicot

Sandwort, Bear Valley Arenaria ursina T California Dicot

Spineflower, Monterey Chorizanthe pungens var.

pungens T California Dicot

Spurge, Hoover's Chamaesyce hooveri T California Dicot

Tarplant, Otay Deinandra (=Hemizonia) conjugens T California Dicot

Tarplant, Santa Cruz Holocarpha macradenia T California Dicot

Thornmint, San Diego Acanthomintha ilicifolia T California Dicot

Vervain, California Verbena californica T California Dicot

Chub, Bonytail Gila elegans E California Fish

Chub, Mohave Tui Gila bicolor mohavensis E California Fish

Chub, Owens Tui Gila bicolor snyderi E California Fish

Goby, Tidewater Eucyclogobius newberryi E California Fish

Pupfish, Desert Cyprinodon macularius E California Fish

Pupfish, Owens Cyprinodon radiosus E California Fish

Squawfish, Colorado Ptychocheilus lucius E California Fish

### 216 INVNAME SCINAME Status STATE

NAME Taxon

Stickleback, Unarmored Threespine Gasterosteus aculeatus

williamsoni E California Fish

Sucker, Lost River Deltistes luxatus E California Fish

Sucker, Modoc Catostomus microps E California Fish

Sucker, Razorback Xyrauchen texanus E California Fish

Sucker, Shortnose Chasmistes brevirostris E California Fish

Salmon, Chinook Oncorhynchus (=Salmo) tshawytscha E/T California Fish

Salmon, Coho Oncorhynchus (=Salmo)

kisutch E/T California Fish

Steelhead Oncorhynchus (=Salmo) mykiss E/T California Fish

Smelt, Delta Hypomesus transpacificus T California Fish

Sturgeon, North American green Acipenser medirostris T California Fish

Sucker, Santa Ana Catostomus santaanae T California Fish

Trout, Lahontan

Cutthroat Oncorhynchus clarki

henshawi T California Fish

Trout, Little Kern

Golden Oncorhynchus aguabonita

whitei T California Fish

Trout, Paiute Cutthroat Oncorhynchus clarki

seleniris T California Fish

Abalone, Black Haliotis cracherodii E California Gastropod

Abalone, White Haliotis sorenseni E California Gastropod

Snail, Morro

Shoulderband Helminthoglypta walkeriana E California Gastropod

Beetle, Casey's June Dinacoma caseyi E California Insect

Beetle, Mount Hermon

June Polyphylla barbata E California Insect

Beetle, Ohlone Tiger Cicindela ohlone E California Insect

Butterfly, Behren's Silverspot Speyeria zerene behrensii E California Insect

Butterfly, Callippe Silverspot Speyeria callippe callippe E California Insect

### 217 INVNAME SCINAME Status STATE

NAME Taxon

Butterfly, El Segundo

Blue Euphilotes battoides allyni E California Insect

Butterfly, Lange's

Metalmark Apodemia mormo langei E California Insect

Butterfly, Lotis Blue Lycaeides argyrognomon

lotis E California Insect

Butterfly, Mission

Blue Icaricia icarioides

missionensis E California Insect

Butterfly, Myrtle's Silverspot Speyeria zerene myrtleae E California Insect

Butterfly, Palos

Verdes Blue Glaucopsyche lygdamus palosverdesensis E California Insect

Butterfly, Quino Checkerspot Euphydryas editha quino (=E. e. wrighti) E California Insect

Butterfly, San Bruno

Elfin Callophrys mossii bayensis E California Insect

Butterfly, Smith's Blue Euphilotes enoptes smithi E California Insect

Fly, Delhi Sands

Flower

- loving Rhaphiomidas terminatus

abdominalis E California Insect

Grasshopper, Zayante

Band

- winged Trimerotropis infantilis E California Insect

Skipper, Carson Wandering Pseudocopaeodes eunus

obscurus E California Insect

Skipper, Laguna

Mountain Pyrgus ruralis lagunae E California Insect

Beetle, Delta Green

Ground Elaphrus viridis T California Insect

Beetle, Valley Elderberry Longhorn Desmocerus californicus dimorphus T California Insect

Butterfly, Bay Checkerspot (Wright's euphydryas) Euphydryas editha bayensis T California Insect

Butterfly, Oregon Silverspot Speyeria zerene hippolyta T California Insect

### 218 INVNAME SCINAME Status STATE

NAME Taxon

Moth, Kern Primrose Sphinx Euproserpinus euterpe T California Insect

Fox, San Joaquin Kit Vulpes macrotis mutica E California Mammal

Fox, San Miguel

Island Urocyon littoralis littoralis E California Mammal

Fox, Santa Catalina

Island Urocyon littoralis catalinae E California Mammal

Fox, Santa Cruz Island Urocyon littoralis

santacruzae E California Mammal

Fox, Santa Rosa Island Urocyon littoralis

santarosae E California Mammal

Jaguar Panthera onca E California Mammal

Kangaroo Rat, Fresno Dipodomys nitratoides exilis E California Mammal

Kangaroo Rat, Giant Dipodomys ingens E California Mammal

Kangaroo Rat, Morro Bay Dipodomys heermanni

morroensis E California Mammal

Kangaroo Rat, San

Bernardino Merriam's Dipodomys merriami parvus E California Mammal

Kangaroo Rat, Stephens' Dipodomys stephensi (incl. D. cascus) E California Mammal

Kangaroo Rat, Tipton Dipodomys nitratoides

nitratoides E California Mammal

Mountain Beaver,

Point Arena Aplodontia rufa nigra E California Mammal

Mouse, Pacific Pocket Perognathus longimembris pacificus E California Mammal

Mouse, Salt Marsh

Harvest Reithrodontomys raviventris E California Mammal

Rabbit, Riparian Brush Sylvilagus bachmani riparius E California Mammal

Sheep, Peninsular Bighorn Ovis canadensis nelsoni E California Mammal

Sheep, Sierra Nevada Bighorn Ovis canadensis sierrae E California Mammal

### 219 INVNAME SCINAME Status STATE

NAME Taxon

Shrew, Buena Vista

Lake Ornate Sorex ornatus relictus E California Mammal

Vole, Amargosa Microtus californicus scirpensis E California Mammal

Whale, Blue Balaenoptera musculus E California Mammal

Whale, Finback Balaenoptera physalus E California Mammal

Whale, Gray Eschrichtius robustus E California Mammal

Whale, Humpback Megaptera novaeangliae E California Mammal

Whale, North Atlantic right Eubalaena glacialis (incl. australis) E California Mammal

Whale, Sei Balaenoptera borealis E California Mammal

Whale, Sperm Physeter catodon (=macrocephalus) E California Mammal

Woodrat, Riparian Neotoma fuscipes riparia E California Mammal

Sea

- lion, Steller Eumetopias jubatus E/T California Mammal

Otter, Southern Sea Enhydra lutris nereis T California Mammal

Seal, Guadalupe Fur Arctocephalus townsendi T California Mammal

Alopecurus, Sonoma Alopecurus aequalis var.

sonomensis E California Monocot

Bluegrass, Napa Poa napensis E California Monocot

Bluegrass, San

Bernardino Poa atropurpurea E California Monocot

Grass, California

Orcutt Orcuttia californica E California Monocot

Grass, Eureka Dune Swallenia alexandrae E California Monocot

Grass, Solano Tuctoria mucronata E California Monocot

Lily, Pitkin Marsh Lilium pardalinum ssp. pitkinense E California Monocot

Lily, Western Lilium occidentale E California Monocot

Onion, Munz's Allium munzii E California Monocot

Piperia, Yadon's Piperia yadonii E California Monocot

### 220 INVNAME SCINAME Status STATE

NAME Taxon

Sedge, White Carex albida E California Monocot

Amole, Cammatta Canyon Chlorogalum purpureum

var. reductum T California Monocot

Amole, Purple Chlorogalum purpureum

var. purpureum T California Monocot

Brodiaea, Chinese Camp Brodiaea pallida T California Monocot

Brodiaea, Thread

leaved Brodiaea filifolia T California Monocot

Grass, Colusa Neostapfia colusana T California Monocot

Grass, San Joaquin Valley Orcutt Orcuttia inaequalis T California Monocot

Lily, Tiburon Mariposa Calochortus tiburonensis T California Monocot

Lizard, Blunt

- nosed Leopard Gambelia silus E California Reptile

Sea turtle, leatherback Dermochelys coriacea E California Reptile

Snake, San Francisco

Garter Thamnophis sirtalis

tetrataenia E California Reptile

Sea turtle, green Chelonia mydas E/T California Reptile

Sea turtle, loggerhead Caretta caretta E/T California Reptile

Lizard, Coachella Valley Fringe

- toed Uma inornata T California Reptile

Lizard, Island Night Xantusia riversiana T California Reptile

Sea turtle, olive ridley Lepidochelys olivacea T California Reptile

Snake, Giant Garter Thamnophis gigas T California Reptile

Tortoise, Desert Gopherus agassizii T California Reptile

Whipsnake (=Striped Racer), Alameda Masticophis lateralis euryxanthus T California Reptile

Crane, Whooping Grus americana E Colorado Bird

Flycatcher,

Southwestern Willow Empidonax traillii extimus E Colorado Bird

Tern, Interior (population) Least Sterna antillarum E Colorado Bird

### 221 INVNAME SCINAME Status STATE

NAME Taxon

Plover, Piping Charadrius melodus E/T Colorado Bird

Owl, Mexican Spotted Strix occidentalis lucida T Colorado Bird

Beardtongue, Penland Penstemon penlandii E Colorado Dicot

Cactus, Knowlton Pediocactus knowltonii E Colorado Dicot

Milk

- vetch, Mancos Astragalus humillimus E Colorado Dicot

Milk

- vetch, Osterhout Astragalus osterhoutii E Colorado Dicot

Pagosa Skyrocket Ipomopsis polyantha E Colorado Dicot

Phacelia, North Park Phacelia formosula E Colorado Dicot

Wild

- buckwheat, Clay

- loving Eriogonum pelinophilum E Colorado Dicot

Bladderpod, Dudley

Bluffs Lesquerella congesta T Colorado Dicot

Butterfly Plant,

Colorado Gaura neomexicana var.

coloradensis T Colorado Dicot

Cactus, Colorado

hookless Sclerocactus glaucus T Colorado Dicot

Cactus, Mesa Verde Sclerocactus mesae

- verdae T Colorado Dicot

DeBeque phacelia Phacelia submutica T Colorado Dicot

Mustard, Penland Alpine Fen Eutrema penlandii T Colorado Dicot

Parachute Beardtongue Penstemon debilis T Colorado Dicot

Twinpod, Dudley

Bluffs Physaria obcordata T Colorado Dicot

Chub, Bonytail Gila elegans E Colorado Fish

Chub, Humpback Gila cypha E Colorado Fish

Squawfish, Colorado Ptychocheilus lucius E Colorado Fish

Sturgeon, Pallid Scaphirhynchus albus E Colorado Fish

Sucker, Razorback Xyrauchen texanus E Colorado Fish

Trout, Greenback

Cutthroat Oncorhynchus clarki

stomias T Colorado Fish

### 222 INVNAME SCINAME Status STATE

NAME Taxon

Butterfly, Uncompahgre Fritillary Boloria acrocnema E Colorado Insect

Skipper, Pawnee

Montane Hesperia leonardus montana T Colorado Insect

Ferret, Black

- footed Mustela nigripes E Colorado Mammal

Gray Wolf Canis lupus E Colorado Mammal

Lynx, Canada Lynx canadensis T Colorado Mammal

Mouse, Preble's Meadow Jumping Zapus hudsonius preblei T Colorado Mammal

Ladies'

- tresses, Ute Spiranthes diluvialis T Colorado Monocot

Plover, Piping Charadrius melodus E/T Connecticut Bird

Tern, Roseate Sterna dougallii dougallii E/T Connecticut Bird

Mussel, Dwarf Wedge Alasmidonta heterodon E Connecticut Bivalve

Chaffseed, American Schwalbea americana E Connecticut Dicot

Gerardia, Sandplain Agalinis acuta E Connecticut Dicot

Sturgeon, Shortnose Acipenser brevirostrum E Connecticut Fish

Beetle, Puritan Tiger Cicindela puritana T Connecticut Insect

Bat, Indiana Myotis sodalis E Connecticut Mammal

Pogonia, Small

Whorled Isotria medeoloides T Connecticut Monocot

Sea turtle, hawksbill Eretmochelys imbricata E Connecticut Reptile

Sea turtle, Kemp's ridley Lepidochelys kempii E Connecticut Reptile

Sea turtle, leatherback Dermochelys coriacea E Connecticut Reptile

Sea turtle, green Chelonia mydas E/T Connecticut Reptile

Sea turtle, loggerhead Caretta caretta E/T Connecticut Reptile

### 223 INVNAME SCINAME Status STATE

NAME Taxon

Turtle, Bog Clemmys muhlenbergii T Connecticut Reptile

Plover, Piping Charadrius melodus E/T Delaware Bird

Dropwort, Canby's Oxypolis canbyi E Delaware Dicot

Amaranth, Seabeach Amaranthus pumilus T Delaware Dicot

Sucker, Shortnose Chasmistes brevirostris E Delaware Fish

Squirrel, Delmarva

Peninsula Fox Sciurus niger cinereus E Delaware Mammal

Whale, Blue Balaenoptera musculus E Delaware Mammal

Whale, Finback Balaenoptera physalus E Delaware Mammal

Whale, Humpback Megaptera novaeangliae E Delaware Mammal

Whale, North Atlantic right Eubalaena glacialis (incl. australis) E Delaware Mammal

Beaked

- rush,

Knieskern's Rhynchospora knieskernii T Delaware Monocot

Pink, Swamp Helonias bullata T Delaware Monocot

Pogonia, Small

Whorled Isotria medeoloides T Delaware Monocot

Sea turtle, hawksbill Eretmochelys imbricata E Delaware Reptile

Sea turtle, Kemp's ridley Lepidochelys kempii E Delaware Reptile

Sea turtle, leatherback Dermochelys coriacea E Delaware Reptile

Sea turtle, green Chelonia mydas E/T Delaware Reptile

Sea turtle, loggerhead Caretta caretta E/T Delaware Reptile

Turtle, Bog Clemmys muhlenbergii T Delaware Reptile

Salamander,

Reticulated flatwoods Ambystoma bishopi E Florida Amphibian

### 224 INVNAME SCINAME Status STATE

NAME Taxon

Salamander, Frosted

Flatwoods Ambystoma cingulatum T Florida Amphibian

Crane, Whooping Grus americana E Florida Bird

Kite, Everglades Snail Rostrhamus sociabilis plumbeus E Florida Bird

Sparrow, Cape Sable

Seaside Ammodramus maritimus

mirabilis E Florida Bird

Sparrow, Florida Grasshopper Ammodramus savannarum floridanus E Florida Bird

Stork, Wood Mycteria americana E Florida Bird

Warbler (=Wood),

Kirtland's Dendroica kirtlandii E Florida Bird

Warbler, Bachman's Vermivora bachmanii E Florida Bird

Woodpecker, Ivory

billed Campephilus principalis E Florida Bird

Woodpecker, Red

cockaded Picoides borealis E Florida Bird

Plover, Piping Charadrius melodus E/T Florida Bird

Caracara, Audubon's

Crested Polyborus plancus

audubonii T Florida Bird

Scrub

- Jay, Florida Aphelocoma coerulescens T Florida Bird

Choctaw Bean Villosa choctawensis E Florida Bivalve

Mussel, Fat Threeridge Amblema neislerii E Florida Bivalve

Mussel, Gulf

Moccasinshell Medionidus penicillatus E Florida Bivalve

Mussel, Ochlockonee

Moccasinshell Medionidus simpsonianus E Florida Bivalve

Mussel, Oval Pigtoe Pleurobema pyriforme E Florida Bivalve

Mussel, Shiny

- rayed

Pocketbook Lampsilis subangulata E Florida Bivalve

Round Ebonyshell Fusconaia rotulata E Florida Bivalve

Southern Kidneyshell Ptychobranchus jonesi E Florida Bivalve

Bankclimber, Purple Elliptoideus sloatianus T Florida Bivalve

### 225 INVNAME SCINAME Status STATE

NAME Taxon

fuzzy pigtoe Pleurobema strodeanum T Florida Bivalve

Narrow Pigtoe Fusconaia escambia T Florida Bivalve

Slabshell, Chipola Elliptio chipolaensis T Florida Bivalve

Southern Sandshell Hamiota australis T Florida Bivalve

Tapered Pigtoe Fusconaia burkei T Florida Bivalve

Torreya, Florida Torreya taxifolia E Florida Conf/cycds

Coral, Elkhorn Acropora palmata T Florida Coral

Coral, Staghorn Acropora cervicornis T Florida Coral

Shrimp, Squirrel Chimney Cave Palaemonetes cummingi T Florida Crustacean

Aster, Florida Golden Chrysopsis floridana E Florida Dicot

Bellflower,

Brooksville Campanula robinsiae E Florida Dicot

Blazing Star, Scrub Liatris ohlingerae E Florida Dicot

Campion, Fringed Silene polypetala E Florida Dicot

Chaffseed, American Schwalbea americana E Florida Dicot

Fringe Tree, Pygmy Chionanthus pygmaeus E Florida Dicot

Gourd, Okeechobee Cucurbita okeechobeensis ssp. okeechobeensis E Florida Dicot

Harebells, Avon Park Crotalaria avonensis E Florida Dicot

Hypericum, Highlands

Scrub Hypericum cumulicola E Florida Dicot

Jacquemontia, Beach Jacquemontia reclinata E Florida Dicot

Lead

- plant, Crenulate Amorpha crenulata E Florida Dicot

Lupine, Scrub Lupinus aridorum E Florida Dicot

Meadowrue, Cooley's Thalictrum cooleyi E Florida Dicot

Milkpea, Small's Galactia smallii E Florida Dicot

Mint, Garrett's Dicerandra christmanii E Florida Dicot

### 226 INVNAME SCINAME Status STATE

NAME Taxon

Mint, Lakela's Dicerandra immaculata E Florida Dicot

Mint, Longspurred Dicerandra cornutissima E Florida Dicot

Mint, Scrub Dicerandra frutescens E Florida Dicot

Mustard, Carter's Warea carteri E Florida Dicot

Pawpaw, Beautiful Deeringothamnus pulchellus E Florida Dicot

Pawpaw, Four

- petal Asimina tetramera E Florida Dicot

Pawpaw, Rugel's Deeringothamnus rugelii E Florida Dicot

Pinkroot, Gentian Spigelia gentianoides E Florida Dicot

Plum, Scrub Prunus geniculata E Florida Dicot

Polygala, Lewton's Polygala lewtonii E Florida Dicot

Polygala, Tiny Polygala smallii E Florida Dicot

Prickly

- apple, Fragrant Cereus eriophorus var. fragrans E Florida Dicot

Rhododendron, Chapman Rhododendron chapmanii E Florida Dicot

Rosemary, Apalachicola Conradina glabra E Florida Dicot

Rosemary, Etonia Conradina etonia E Florida Dicot

Rosemary, Short

leaved Conradina brevifolia E Florida Dicot

Sandlace Polygonella myriophylla E Florida Dicot

Snakeroot Eryngium cuneifolium E Florida Dicot

Spurge, Deltoid Chamaesyce deltoidea ssp.

deltoidea E Florida Dicot

Warea, Wide

- leaf Warea amplexifolia E Florida Dicot

Water

- willow, Cooley's Justicia cooleyi E Florida Dicot

Wireweed Polygonella basiramia E Florida Dicot

Ziziphus, Florida Ziziphus celata E Florida Dicot

### 227 INVNAME SCINAME Status STATE

NAME Taxon

Birds

- in

- a

- nest, White Macbridea alba T Florida Dicot

Bonamia, Florida Bonamia grandiflora T Florida Dicot

Buckwheat, Scrub Eriogonum longifolium var. gnaphalifolium T Florida Dicot

Butterwort, Godfrey's Pinguicula ionantha T Florida Dicot

Gooseberry,

Miccosukee Ribes echinellum T Florida Dicot

Skullcap, Florida Scutellaria floridana T Florida Dicot

Spurge, Garber's Chamaesyce garberi T Florida Dicot

Spurge, Telephus Euphorbia telephioides T Florida Dicot

Whitlow

- wort, Papery Paronychia chartacea T Florida Dicot

Wings, Pigeon Clitoria fragrans T Florida Dicot

Darter, Okaloosa Etheostoma okaloosae E Florida Fish

Sawfish, Smalltooth Pristis pectinata E Florida Fish

Sturgeon, Shortnose Acipenser brevirostrum E Florida Fish

Sturgeon, Gulf Acipenser oxyrinchus

desotoi T Florida Fish

Butterfly, Miami Blue Cyclargus thomasi

bethunebakeri E Florida Insect

Cladonia, Florida

Perforate Cladonia perforata E Florida Lichen

Bat, Gray Myotis grisescens E Florida Mammal

Bat, Indiana Myotis sodalis E Florida Mammal

Manatee, West Indian Trichechus manatus E Florida Mammal

Mouse, Anastasia

Island Beach Peromyscus polionotus phasma E Florida Mammal

Mouse,

Choctawhatchee

Beach Peromyscus polionotus allophrys E Florida Mammal

Mouse, Perdido Key

Beach Peromyscus polionotus trissyllepsis E Florida Mammal

### 228 INVNAME SCINAME Status STATE

NAME Taxon

Mouse, St. Andrew

Beach Peromyscus polionotus peninsularis E Florida Mammal

Panther, Florida Puma (=Felis) concolor coryi E Florida Mammal

Puma (=Cougar),

Eastern Puma (=Felis) concolor (all subsp. except coryi) E Florida Mammal

Vole, Florida Salt

Marsh Microtus pennsylvanicus dukecampbelli E Florida Mammal

Mouse, Southeastern

Beach Peromyscus polionotus

niveiventris T Florida Mammal

Beargrass, Britton's Nolina brittoniana E Florida Monocot

Beauty, Harper's Harperocallis flava E Florida Monocot

Seagrass, Johnson's Halophila johnsonii T Florida Monocot

Sea turtle, hawksbill Eretmochelys imbricata E Florida Reptile

Sea turtle, Kemp's ridley Lepidochelys kempii E Florida Reptile

Sea turtle, leatherback Dermochelys coriacea E Florida Reptile

Sea turtle, green Chelonia mydas E/T Florida Reptile

Sea turtle, loggerhead Caretta caretta E/T Florida Reptile

Alligator, American Alligator mississippiensis T Florida Reptile

Crocodile, American Crocodylus acutus T Florida Reptile

Skink, Blue

- tailed

Mole Eumeces egregius lividus T Florida Reptile

Skink, Sand Neoseps reynoldsi T Florida Reptile

Snake, Atlantic Salt

Marsh Nerodia clarkii taeniata T Florida Reptile

Snake, Eastern Indigo Drymarchon corais couperi T Florida Reptile

Salamander,

Reticulated flatwoods Ambystoma bishopi E Georgia Amphibian

### 229 INVNAME SCINAME Status STATE

NAME Taxon

Salamander, Frosted

Flatwoods Ambystoma cingulatum T Georgia Amphibian

Stork, Wood Mycteria americana E Georgia Bird

Warbler (=Wood),

Kirtland's Dendroica kirtlandii E Georgia Bird

Warbler, Bachman's Vermivora bachmanii E Georgia Bird

Woodpecker, Red

cockaded Picoides borealis E Georgia Bird

Plover, Piping Charadrius melodus E/T Georgia Bird

Tern, Roseate Sterna dougallii dougallii E/T Georgia Bird

Combshell, Upland Epioblasma metastriata E Georgia Bivalve

Kidneyshell, Triangular Ptychobranchus greenii E Georgia Bivalve

Mussel, Acornshell

Southern Epioblasma othcaloogensis E Georgia Bivalve

Mussel, Coosa

Moccasinshell Medionidus parvulus E Georgia Bivalve

Mussel, Fat Threeridge Amblema neislerii E Georgia Bivalve

Mussel, Georgia pigtoe Pleurobema hanleyianum E Georgia Bivalve

Mussel, Gulf

Moccasinshell Medionidus penicillatus E Georgia Bivalve

Mussel, Ochlockonee

Moccasinshell Medionidus simpsonianus E Georgia Bivalve

Mussel, Oval Pigtoe Pleurobema pyriforme E Georgia Bivalve

Mussel, Ovate

Clubshell Pleurobema perovatum E Georgia Bivalve

Mussel, Shiny

- rayed

Pocketbook Lampsilis subangulata E Georgia Bivalve

Mussel, Southern

Clubshell Pleurobema decisum E Georgia Bivalve

Mussel, Southern Pigtoe Pleurobema georgianum E Georgia Bivalve

Spinymussel,

Altamaha Elliptio spinosa E Georgia Bivalve

### 230 INVNAME SCINAME Status STATE

NAME Taxon

Bankclimber, Purple Elliptoideus sloatianus T Georgia Bivalve

Mussel, Alabama

Moccasinshell Medionidus acutissimus T Georgia Bivalve

Mussel, Fine

- lined

Pocketbook Lampsilis altilis T Georgia Bivalve

Torreya, Florida Torreya taxifolia E Georgia Conf/cycds

Campion, Fringed Silene polypetala E Georgia Dicot

Chaffseed, American Schwalbea americana E Georgia Dicot

Coneflower, Smooth Echinacea laevigata E Georgia Dicot

Dropwort, Canby's Oxypolis canbyi E Georgia Dicot

Harperella Ptilimnium nodosum E Georgia Dicot

Leather

- flower,

Alabama Clematis socialis E Georgia Dicot

Meadowrue, Cooley's Thalictrum cooleyi E Georgia Dicot

Pitcher

- plant, Green Sarracenia oreophila E Georgia Dicot

Pondberry Lindera melissifolia E Georgia Dicot

Rattleweed, Hairy Baptisia arachnifera E Georgia Dicot

Sumac, Michaux's Rhus michauxii E Georgia Dicot

Amphianthus, Little Amphianthus pusillus T Georgia Dicot

Barbara Buttons,

Mohr's Marshallia mohrii T Georgia Dicot

Skullcap, Large

flowered Scutellaria montana T Georgia Dicot

Spiraea, Virginia Spiraea virginiana T Georgia Dicot

Quillwort, Black

spored Isoetes melanospora E Georgia Ferns

Quillwort, Mat

forming Isoetes tegetiformans E Georgia Ferns

Darter, Amber Percina antesella E Georgia Fish

Darter, Etowah Etheostoma etowahae E Georgia Fish

Logperch, Conasauga Percina jenkinsi E Georgia Fish

### 231 INVNAME SCINAME Status STATE

NAME Taxon

Sturgeon, Shortnose Acipenser brevirostrum E Georgia Fish

Darter, Cherokee Etheostoma scotti T Georgia Fish

Darter, Goldline Percina aurolineata T Georgia Fish

Darter, Snail Percina tanasi T Georgia Fish

Shiner, Blue Cyprinella caerulea T Georgia Fish

Hornsnail, rough Pleurocera foremani E Georgia Gastropod

Rocksnail, interrupted Leptoxis foremani E Georgia Gastropod

Snail, Lioplax Cylindrical Lioplax cyclostomaformis E Georgia Gastropod

Lichen, Rock Gnome Gymnoderma lineare E Georgia Lichen

Bat, Gray Myotis grisescens E Georgia Mammal

Bat, Indiana Myotis sodalis E Georgia Mammal

Manatee, West Indian Trichechus manatus E Georgia Mammal

Whale, Blue Balaenoptera musculus E Georgia Mammal

Whale, Humpback Megaptera novaeangliae E Georgia Mammal

Whale, North Atlantic right Eubalaena glacialis (incl. australis) E Georgia Mammal

Grass, Tennessee

Yellow

- eyed Xyris tennesseensis E Georgia Monocot

Trillium, Persistent Trillium persistens E Georgia Monocot

Trillium, Relict Trillium reliquum E Georgia Monocot

Pink, Swamp Helonias bullata T Georgia Monocot

Pogonia, Small

Whorled Isotria medeoloides T Georgia Monocot

Water

- plantain, Kral's Sagittaria secundifolia T Georgia Monocot

Sea turtle, hawksbill Eretmochelys imbricata E Georgia Reptile

Sea turtle, Kemp's ridley Lepidochelys kempii E Georgia Reptile

Sea turtle, leatherback Dermochelys coriacea E Georgia Reptile

Sea turtle, green Chelonia mydas E/T Georgia Reptile

### 232 INVNAME SCINAME Status STATE

NAME Taxon

Sea turtle, loggerhead Caretta caretta E/T Georgia Reptile

Snake, Eastern Indigo Drymarchon corais couperi T Georgia Reptile

Turtle, Bog Clemmys muhlenbergii T Georgia Reptile

Crow, Mariana Corvus kubaryi E Guam Bird

Kingfisher, Guam

Micronesian Halcyon cinnamomina

cinnamomina E Guam Bird

Moorhen, Mariana

Common Gallinula chloropus guami E Guam Bird

Rail, Guam Rallus owstoni E Guam Bird

White

- eye, Bridled (Nossa) Zosterops conspicillatus conspicillatus E Guam Bird

Hayun Lagu (Tronkon Guafi) Serianthes nelsonii E Guam Dicot

Bat, Little Mariana

Fruit Pteropus tokudae E Guam Mammal

Bat, Mariana Fruit (=Mariana Flying Fox) Pteropus mariannus

mariannus T Guam Mammal

Sea turtle, hawksbill Eretmochelys imbricata E Guam Reptile

Sea turtle, leatherback Dermochelys coriacea E Guam Reptile

Sea turtle, green Chelonia mydas E/T Guam Reptile

Sea turtle, loggerhead Caretta caretta E/T Guam Reptile

Spider, Kauai Cave

Wolf Adelocosa anops E Hawaii Arachnid

Akekee Loxops caeruleirostris E Hawaii Bird

'Akepa, Hawaii Loxops coccineus coccineus E Hawaii Bird

'Akepa, Maui Loxops coccineus ochraceus E Hawaii Bird

'Akia Loa, Kauai (Hemignathus procerus) Hemignathus procerus E Hawaii Bird

### 233 INVNAME SCINAME Status STATE

NAME Taxon

'Akia Pola'au (Hemignathus munroi) Hemignathus munroi E Hawaii Bird

Coot, Hawaiian (=Alae keo keo) Fulica americana alai E Hawaii Bird

Creeper, Hawaii Oreomystis mana E Hawaii Bird

Creeper, Oahu (Alauwahio) Paroreomyza maculata E Hawaii Bird

Crow, Hawaiian ('Alala) Corvus hawaiiensis E Hawaii Bird

Duck, Hawaiian (Koloa) Anas wyvilliana E Hawaii Bird

Elepaio, Oahu Chasiempis sandwichensis

ibidis E Hawaii Bird

Goose, Hawaiian (Nene) Branta (=Nesochen)

sandvicensis E Hawaii Bird

Hawk, Hawaiian (Io) Buteo solitarius E Hawaii Bird

Honeycreeper, Crested ('Akohekohe) Palmeria dolei E Hawaii Bird

Kauai creeper Oreomystis bairdi E Hawaii Bird

Moorhen, Hawaiian

Common Gallinula chloropus

sandvicensis E Hawaii Bird

Nuku Pu'u, Kauai Hemignathus lucidus hanapepe E Hawaii Bird

Nuku Pu'u, Maui Hemignathus lucidus affinus E Hawaii Bird

'O'o, Kauai (='A'a) Moho braccatus E Hawaii Bird

'O'u (Honeycreeper) Psittirostra psittacea E Hawaii Bird

Palila Loxioides bailleui E Hawaii Bird

Parrotbill, Maui Pseudonestor xanthophrys E Hawaii Bird

Petrel, Hawaiian Dark

rumped Pterodroma phaeopygia

sandwichensis E Hawaii Bird

Po'ouli Melamprosops phaeosoma E Hawaii Bird

Stilt, Hawaiian (=Ae'o) Himantopus mexicanus

knudseni E Hawaii Bird

### 234 INVNAME SCINAME Status STATE

NAME Taxon

Swiftlet, Mariana Gray (=Vanikoro) Aerodramus vanikorensis

bartschi E Hawaii Bird

Thrush, Large Kauai Myadestes myadestinus E Hawaii Bird

Thrush, Small Kauai (Puaiohi) Myadestes palmeri E Hawaii Bird

Shearwater, Newell's

Townsend's Puffinus auricularis newelli T Hawaii Bird

Amphipod, Kauai

Cave Spelaeorchestia koloana E Hawaii Crustacean

(ncn) Cyanea kolekoleensis E Hawaii Dicot

(ncn) Keysseria (=Lagenifera)

erici E Hawaii Dicot

(ncn) Keysseria (=Lagenifera)

helenae E Hawaii Dicot

(ncn) Lysimachia iniki E Hawaii Dicot

(ncn) Lysimachia pendens E Hawaii Dicot

(ncn) Lysimachia scopulensis E Hawaii Dicot

(ncn) Lysimachia venosa E Hawaii Dicot

(ncn) Phyllostegia hispida E Hawaii Dicot

(ncn) Phyllostegia renovans E Hawaii Dicot

(ncn) Platydesma cornuta var.

cornuta E Hawaii Dicot

(ncn) Platydesma cornuta var.

decurrens E Hawaii Dicot

(ncn) Schiedea attenuata E Hawaii Dicot

(ncn) Stenogyne kealiae E Hawaii Dicot

(ncn) Tetraplasandra bisattenuata E Hawaii Dicot

(ncn) Tetraplasandra flynnii E Hawaii Dicot

(ncn) Tetraplasandra lydgatei E Hawaii Dicot

Abutilon sandwicense (ncn) Abutilon sandwicense E Hawaii Dicot

### 235 INVNAME SCINAME Status STATE

NAME Taxon

Achyranthes mutica (ncn) Achyranthes mutica E Hawaii Dicot

Achyranthes splendens var. rotundata (ncn) Achyranthes splendens var.

rotundata E Hawaii Dicot

a'e Zanthoxylum oahuense E Hawaii Dicot

A'e (Zanthoxylum dipetalum var. tomentosum) Zanthoxylum dipetalum var.

tomentosum E Hawaii Dicot

A'e (Zanthoxylum hawaiiense) Zanthoxylum hawaiiense E Hawaii Dicot

'Aiea (Nothocestrum breviflorum) Nothocestrum breviflorum E Hawaii Dicot

'Aiea (Nothocestrum peltatum) Nothocestrum peltatum E Hawaii Dicot

Akoko Chamaesyce remyi var.

kauaiensis E Hawaii Dicot

'akoko Chamaesyce eleanoriae E Hawaii Dicot

'Akoko (Chamaesyce

celastroides var. kaenana) Chamaesyce celastroides

var. kaenana E Hawaii Dicot

'Akoko (Chamaesyce deppeana) Chamaesyce deppeana E Hawaii Dicot

'Akoko (Chamaesyce herbstii) Chamaesyce herbstii E Hawaii Dicot

'Akoko (Chamaesyce kuwaleana) Chamaesyce kuwaleana E Hawaii Dicot

'Akoko (Chamaesyce rockii) Chamaesyce rockii E Hawaii Dicot

### 236 INVNAME SCINAME Status STATE

NAME Taxon

'Akoko (Chamaesyce skottsbergii var.

skottsbe Chamaesyce skottsbergii

var. kalaeloana E Hawaii Dicot

'Akoko (Euphorbia haeleeleana) Euphorbia haeleeleana E Hawaii Dicot

alani Melicope christophersenii E Hawaii Dicot

alani Melicope degeneri E Hawaii Dicot

alani Melicope hiiakae E Hawaii Dicot

alani Melicope makahae E Hawaii Dicot

alani Melicope paniculata E Hawaii Dicot

alani Melicope puberula E Hawaii Dicot

Alani (Melicope adscendens) Melicope adscendens E Hawaii Dicot

Alani (Melicope balloui) Melicope balloui E Hawaii Dicot

Alani (Melicope haupuensis) Melicope haupuensis E Hawaii Dicot

Alani (Melicope knudsenii) Melicope knudsenii E Hawaii Dicot

Alani (Melicope lydgatei) Melicope lydgatei E Hawaii Dicot

Alani (Melicope mucronulata) Melicope mucronulata E Hawaii Dicot

Alani (Melicope ovalis) Melicope ovalis E Hawaii Dicot

Alani (Melicope pallida) Melicope pallida E Hawaii Dicot

Alani (Melicope quadrangularis) Melicope quadrangularis E Hawaii Dicot

Alani (Melicope saint

johnii) Melicope saint

- johnii E Hawaii Dicot

Alani (Melicope zahlbruckneri) Melicope zahlbruckneri E Hawaii Dicot

Alsinidendron obovatum (ncn) Alsinidendron obovatum E Hawaii Dicot

Alsinidendron trinerve (ncn) Alsinidendron trinerve E Hawaii Dicot

Alsinidendron viscosum (ncn) Alsinidendron viscosum E Hawaii Dicot

### 237 INVNAME SCINAME Status STATE

NAME Taxon

'Anaunau (Lepidium arbuscula) Lepidium arbuscula E Hawaii Dicot

'Anunu (Sicyos alba) Sicyos alba E Hawaii Dicot

Aupaka (Isodendrion hosakae) Isodendrion hosakae E Hawaii Dicot

Aupaka (Isodendrion laurifolium) Isodendrion laurifolium E Hawaii Dicot

awikiwiki Canavalia napaliensis E Hawaii Dicot

'Awiwi (Centaurium sebaeoides) Centaurium sebaeoides E Hawaii Dicot

'Awiwi (Hedyotis cookiana) Hedyotis cookiana E Hawaii Dicot

Bonamia menziesii (ncn) Bonamia menziesii E Hawaii Dicot

Chamaesyce Halemanui (ncn) Chamaesyce halemanui E Hawaii Dicot

Cyanea undulata (ncn) Cyanea undulata E Hawaii Dicot

Delissea rhytodisperma (ncn) Delissea rhytidosperma E Hawaii Dicot

Dubautia latifolia (ncn) Dubautia latifolia E Hawaii Dicot

Dubautia pauciflorula (ncn) Dubautia pauciflorula E Hawaii Dicot

Geranium, Hawaiian

Red

- flowered Geranium arboreum E Hawaii Dicot

Gouania hillebrandii (ncn) Gouania hillebrandii E Hawaii Dicot

Gouania meyenii (ncn) Gouania meyenii E Hawaii Dicot

Gouania vitifolia (ncn) Gouania vitifolia E Hawaii Dicot

ha`iwale Cyrtandra kaulantha E Hawaii Dicot

### 238 INVNAME SCINAME Status STATE

NAME Taxon

ha`iwale Cyrtandra sessilis E Hawaii Dicot

Haha Cyanea calycina E Hawaii Dicot

Haha Cyanea dolichopoda E Hawaii Dicot

haha Cyanea eleeleensis E Hawaii Dicot

Haha Cyanea kuhihewa E Hawaii Dicot

Haha Cyanea lanceolata E Hawaii Dicot

haha Cyanea purpurellifolia E Hawaii Dicot

Haha (Cyanea acuminata) Cyanea acuminata E Hawaii Dicot

Haha (Cyanea asarifolia) Cyanea asarifolia E Hawaii Dicot

Haha (Cyanea copelandii ssp. copelandii) Cyanea copelandii ssp. copelandii E Hawaii Dicot

Haha (Cyanea copelandii ssp. haleakalaensis) Cyanea copelandii ssp.

haleakalaensis E Hawaii Dicot

Haha (Cyanea Crispa) (=Rollandia crispa) Cyanea (=Rollandia) crispa E Hawaii Dicot

Haha (Cyanea glabra) Cyanea glabra E Hawaii Dicot

Haha (Cyanea grimesiana ssp. grimesiana) Cyanea grimesiana ssp. grimesiana E Hawaii Dicot

Haha (Cyanea grimesiana ssp. obatae) Cyanea grimesiana ssp.

obatae E Hawaii Dicot

Haha (Cyanea hamatiflora ssp. carlsonii) Cyanea hamatiflora ssp.

Carlsonii E Hawaii Dicot

Haha (Cyanea hamatiflora ssp. hamatiflora) Cyanea hamatiflora ssp. hamatiflora E Hawaii Dicot

Haha (Cyanea humboldtiana) Cyanea humboldtiana E Hawaii Dicot

Haha (Cyanea koolauensis) Cyanea koolauensis E Hawaii Dicot

Haha (Cyanea lobata) Cyanea lobata E Hawaii Dicot

### 239 INVNAME SCINAME Status STATE

NAME Taxon

Haha (Cyanea longiflora) Cyanea longiflora E Hawaii Dicot

Haha (Cyanea mceldowneyi) Cyanea mceldowneyi E Hawaii Dicot

Haha (Cyanea pinnatifida) Cyanea pinnatifida E Hawaii Dicot

Haha (Cyanea platyphylla) Cyanea platyphylla E Hawaii Dicot

Haha (Cyanea remyi) Cyanea remyi E Hawaii Dicot

Haha (Cyanea shipmanii) Cyanea shipmannii E Hawaii Dicot

Haha (Cyanea stictophylla) Cyanea stictophylla E Hawaii Dicot

Haha (Cyanea St

Johnii) (=Rollandia St

Johnii) Cyanea st

- johnii E Hawaii Dicot

Haha (Cyanea superba) Cyanea superba E Hawaii Dicot

Haha (Cyanea truncata) Cyanea truncata E Hawaii Dicot

haiwale Cyrtandra gracilis E Hawaii Dicot

haiwale Cyrtandra paliku E Hawaii Dicot

haiwale Cyrtandra waiolani E Hawaii Dicot

Ha'Iwale (Cyrtandra crenata) Cyrtandra crenata E Hawaii Dicot

Ha'Iwale (Cyrtandra dentata) Cyrtandra dentata E Hawaii Dicot

Ha'Iwale (Cyrtandra giffardii) Cyrtandra giffardii E Hawaii Dicot

Ha'Iwale (Cyrtandra munroi) Cyrtandra munroi E Hawaii Dicot

Ha'iwale (Cyrtandra oenobarba) Cyrtandra oenobarba E Hawaii Dicot

Ha'Iwale (Cyrtandra polyantha) Cyrtandra polyantha E Hawaii Dicot

Ha'Iwale (Cyrtandra subumbellata) Cyrtandra subumbellata E Hawaii Dicot

### 240 INVNAME SCINAME Status STATE

NAME Taxon

Ha'Iwale (Cyrtandra tintinnabula) Cyrtandra tintinnabula E Hawaii Dicot

Ha'Iwale (Cyrtandra viridiflora) Cyrtandra viridiflora E Hawaii Dicot

Haplostachys Haplostachya (ncn) Haplostachys haplostachya E Hawaii Dicot

Hau Kauhiwi (Hibiscadelphus woodi) Hibiscadelphus woodii E Hawaii Dicot

Hau Kuahiwi (Hibiscadelphus distans) Hibiscadelphus distans E Hawaii Dicot

Hau Kuahiwi (Hibiscadelphus giffardianus) Hibiscadelphus giffardianus E Hawaii Dicot

Hau Kuahiwi (Hibiscadelphus hualalaiensis) Hibiscadelphus

hualalaiensis E Hawaii Dicot

Heau (Exocarpos luteolus) Exocarpos luteolus E Hawaii Dicot

Hedyotis degeneri (ncn) Hedyotis degeneri E Hawaii Dicot

Hedyotis parvula (ncn) Hedyotis parvula E Hawaii Dicot

Hedyotis St.

- Johnii (ncn) Hedyotis st.

- johnii E Hawaii Dicot

Hesperomannia arborescens (ncn) Hesperomannia arborescens E Hawaii Dicot

Hesperomannia arbuscula (ncn) Hesperomannia arbuscula E Hawaii Dicot

Hesperomannia lydgatei (ncn) Hesperomannia lydgatei E Hawaii Dicot

Hibiscus, Clay's Hibiscus clayi E Hawaii Dicot

ho'awa Pittosporum napaliense E Hawaii Dicot

Holei (Ochrosia kilaueaensis) Ochrosia kilaueaensis E Hawaii Dicot

Iliau (Wilkesia hobdyi) Wilkesia hobdyi E Hawaii Dicot

### 241 INVNAME SCINAME Status STATE

NAME Taxon

kamakahala Labordia helleri E Hawaii Dicot

kamakahala Labordia pumila E Hawaii Dicot

Kamakahala (Labordia cyrtandrae) Labordia cyrtandrae E Hawaii Dicot

Kamakahala (Labordia lydgatei) Labordia lydgatei E Hawaii Dicot

Kamakahala (Labordia

tinifolia var. wahiawaen) Labordia tinifolia var.

wahiawaensis E Hawaii Dicot

Kauila (Colubrina oppositifolia) Colubrina oppositifolia E Hawaii Dicot

kaulu Pteralyxia macrocarpa E Hawaii Dicot

Kaulu (Pteralyxia kauaiensis) Pteralyxia kauaiensis E Hawaii Dicot

Kio'Ele (Hedyotis coriacea) Hedyotis coriacea E Hawaii Dicot

Kiponapona (Phyllostegia racemosa) Phyllostegia racemosa E Hawaii Dicot

ko`oko`olau Bidens amplectens E Hawaii Dicot

Koki'o (Kokia drynarioides) Kokia drynarioides E Hawaii Dicot

Koki'o (Kokia kauaiensis) Kokia kauaiensis E Hawaii Dicot

Koki'o Ke'oke'o (Hibiscus waimeae ssp. hannerae) Hibiscus waimeae ssp.

hannerae E Hawaii Dicot

Kolea Myrsine knudsenii E Hawaii Dicot

kolea Myrsine mezii E Hawaii Dicot

Kolea (Myrsine juddii) Myrsine juddii E Hawaii Dicot

Ko'oko'olau (Bidens micrantha ssp. kalealaha) Bidens micrantha ssp.

kalealaha E Hawaii Dicot

Ko'oloa'ula (Abutilon menziesii) Abutilon menziesii E Hawaii Dicot

kopiko Psychotria grandiflora E Hawaii Dicot

kopiko Psychotria hobdyi E Hawaii Dicot

### 242 INVNAME SCINAME Status STATE

NAME Taxon

Kuawawaenohu (Alsinidendron lychnoides) Alsinidendron lychnoides E Hawaii Dicot

Kulu'I (Nototrichium humile) Nototrichium humile E Hawaii Dicot

Laukahi Kuahiwi (Plantago hawaiensis) Plantago hawaiensis E Hawaii Dicot

Laukahi Kuahiwi (Plantago princeps) Plantago princeps E Hawaii Dicot

Laulihilihi (Schiedea stellarioides) Schiedea stellarioides E Hawaii Dicot

lehua makanoe Lysimachia daphnoides E Hawaii Dicot

Liliwai (Acaena exigua) Acaena exigua E Hawaii Dicot

Lipochaeta venosa (ncn) Lipochaeta venosa E Hawaii Dicot

Lobelia monostachya (ncn) Lobelia monostachya E Hawaii Dicot

Lobelia niihauensis (ncn) Lobelia niihauensis E Hawaii Dicot

Lobelia oahuensis (ncn) Lobelia oahuensis E Hawaii Dicot

Lysimachia filifolia (ncn) Lysimachia filifolia E Hawaii Dicot

Lysimachia lydgatei (ncn) Lysimachia lydgatei E Hawaii Dicot

Mahoe (Alectryon macrococcus) Alectryon macrococcus E Hawaii Dicot

Ma'o Hau Hele (Hibiscus brackenridgei) Hibiscus brackenridgei E Hawaii Dicot

Ma'oli'oli (Schiedea apokremnos) Schiedea apokremnos E Hawaii Dicot

Ma'oli'oli (Schiedea kealiae) Schiedea kealiae E Hawaii Dicot

Mapele (Cyrtandra cyaneoides) Cyrtandra cyaneoides E Hawaii Dicot

### 243 INVNAME SCINAME Status STATE

NAME Taxon

Mehamehame (Flueggea neowawraea) Flueggea neowawraea E Hawaii Dicot

Munroidendron racemosum (ncn) Munroidendron racemosum E Hawaii Dicot

na`ena`e Dubautia imbricata

imbricata E Hawaii Dicot

na`ena`e Dubautia plantaginea magnifolia E Hawaii Dicot

Na`ena`e Dubautia waialealae E Hawaii Dicot

Naenae Dubautia kalalauensis E Hawaii Dicot

Naenae Dubautia kenwoodii E Hawaii Dicot

Na'ena'e (Dubautia herbstobatae) Dubautia herbstobatae E Hawaii Dicot

Na'ena'e (Dubautia plantaginea ssp. humilis) Dubautia plantaginea ssp.

humilis E Hawaii Dicot

Nani Wai'ale'ale (Viola

kauaensis var. wahiawaensis) Viola kauaiensis var.

wahiawaensis E Hawaii Dicot

Nanu (Gardenia mannii) Gardenia mannii E Hawaii Dicot

Na'u (Gardenia brighamii) Gardenia brighamii E Hawaii Dicot

Naupaka, Dwarf (Scaevola coriacea) Scaevola coriacea E Hawaii Dicot

Nehe (Lipochaeta fauriei) Lipochaeta fauriei E Hawaii Dicot

Nehe (Lipochaeta kamolensis) Lipochaeta kamolensis E Hawaii Dicot

Nehe (Lipochaeta lobata var. leptophylla) Lipochaeta lobata var. leptophylla E Hawaii Dicot

Nehe (Lipochaeta micrantha) Lipochaeta micrantha E Hawaii Dicot

Nehe (Lipochaeta tenuifolia) Lipochaeta tenuifolia E Hawaii Dicot

Nehe (Lipochaeta waimeaensis) Lipochaeta waimeaensis E Hawaii Dicot

### 244 INVNAME SCINAME Status STATE

NAME Taxon

Neraudia angulata (ncn) Neraudia angulata E Hawaii Dicot

Neraudia ovata (ncn) Neraudia ovata E Hawaii Dicot

Neraudia sericea (ncn) Neraudia sericea E Hawaii Dicot

Nioi (Eugenia koolauensis) Eugenia koolauensis E Hawaii Dicot

nohoanu Geranium kauaiense E Hawaii Dicot

Nohoanu (Geranium multiflorum) Geranium multiflorum E Hawaii Dicot

Oahu wild coffee Psychotria hexandra ssp.

Oahuensis E Hawaii Dicot

'Oha (Delissea rivularis) Delissea rivularis E Hawaii Dicot

'Oha (Delissea subcordata) Delissea subcordata E Hawaii Dicot

'Oha (Delissea undulata) Delissea undulata E Hawaii Dicot

'Oha (Lobelia gaudichaudii koolauensis) Lobelia gaudichaudii ssp.

koolauensis E Hawaii Dicot

'Oha Wai (Clermontia drepanomorpha) Clermontia drepanomorpha E Hawaii Dicot

'Oha Wai (Clermontia lindseyana) Clermontia lindseyana E Hawaii Dicot

'Oha Wai (Clermontia oblongifolia ssp. mauiensis) Clermontia oblongifolia ssp.

mauiensis E Hawaii Dicot

'Oha Wai (Clermontia peleana) Clermontia peleana E Hawaii Dicot

'Oha Wai (Clermontia pyrularia) Clermontia pyrularia E Hawaii Dicot

### 245 INVNAME SCINAME Status STATE

NAME Taxon

'Oha Wai (Clermontia samuelii) Clermontia samuelii E Hawaii Dicot

'Ohai (Sesbania tomentosa) Sesbania tomentosa E Hawaii Dicot

'Ohe'ohe (Tetraplasandra gymnocarpa) Tetraplasandra gymnocarpa E Hawaii Dicot

'Olulu (Brighamia insignis) Brighamia insignis E Hawaii Dicot

Opuhe (Urera kaalae) Urera kaalae E Hawaii Dicot

Pamakani (Viola chamissoniana ssp. chamissoniana) Viola chamissoniana ssp.

chamissoniana E Hawaii Dicot

Papala Charpentiera densiflora E Hawaii Dicot

Phyllostegia hirsuta (ncn) Phyllostegia hirsuta E Hawaii Dicot

Phyllostegia kaalaensis (ncn) Phyllostegia kaalaensis E Hawaii Dicot

Phyllostegia knudsenii (ncn) Phyllostegia knudsenii E Hawaii Dicot

Phyllostegia mannii (ncn) Phyllostegia mannii E Hawaii Dicot

Phyllostegia mollis (ncn) Phyllostegia mollis E Hawaii Dicot

Phyllostegia parviflora (ncn) Phyllostegia parviflora E Hawaii Dicot

Phyllostegia velutina (ncn) Phyllostegia velutina E Hawaii Dicot

Phyllostegia waimeae (ncn) Phyllostegia waimeae E Hawaii Dicot

Phyllostegia warshaueri (ncn) Phyllostegia warshaueri E Hawaii Dicot

Phyllostegia wawrana (ncn) Phyllostegia wawrana E Hawaii Dicot

Pilo (Hedyotis mannii) Hedyotis mannii E Hawaii Dicot

pilo kea lau li`i Platydesma rostrata E Hawaii Dicot

### 246 INVNAME SCINAME Status STATE

NAME Taxon

Po'e (Portulaca sclerocarpa) Portulaca sclerocarpa E Hawaii Dicot

Popolo 'Aiakeakua (Solanum sandwicense) Solanum sandwicense E Hawaii Dicot

Popolo Ku Mai (Solanum incompletum) Solanum incompletum E Hawaii Dicot

Pua'ala (Brighamia rockii) Brighamia rockii E Hawaii Dicot

Remya kauaiensis (ncn) Remya kauaiensis E Hawaii Dicot

Remya montgomeryi (ncn) Remya montgomeryi E Hawaii Dicot

Remya, Maui Remya mauiensis E Hawaii Dicot

Sandalwood, Lanai (='Iliahi) Santalum freycinetianum

var. lanaiense E Hawaii Dicot

Sanicula mariversa (ncn) Sanicula mariversa E Hawaii Dicot

Sanicula purpurea (ncn) Sanicula purpurea E Hawaii Dicot

Schiedea haleakalensis (ncn) Schiedea haleakalensis E Hawaii Dicot

Schiedea helleri (ncn) Schiedea helleri E Hawaii Dicot

Schiedea hookeri (ncn) Schiedea hookeri E Hawaii Dicot

Schiedea kaalae (ncn) Schiedea kaalae E Hawaii Dicot

Schiedea kauaiensis (ncn) Schiedea kauaiensis E Hawaii Dicot

Schiedea membranacea (ncn) Schiedea membranacea E Hawaii Dicot

Schiedea nuttallii (ncn) Schiedea nuttallii E Hawaii Dicot

Schiedea spergulina var. leiopoda (ncn) Schiedea spergulina var. leiopoda E Hawaii Dicot

Schiedea, Diamond Head (Schiedea adamantis) Schiedea adamantis E Hawaii Dicot

### 247 INVNAME SCINAME Status STATE

NAME Taxon

Silene lanceolata (ncn) Silene lanceolata E Hawaii Dicot

Silene perlmanii (ncn) Silene perlmanii E Hawaii Dicot

Silversword, Ka'u (Argyroxiphium kauense) Argyroxiphium kauense E Hawaii Dicot

Silversword, Mauna Kea ('Ahinahina) Argyroxiphium sandwicense ssp. sandwicense E Hawaii Dicot

Spermolepis hawaiiensis (ncn) Spermolepis hawaiiensis E Hawaii Dicot

Stenogyne angustifolia (ncn) Stenogyne angustifolia var. angustifolia E Hawaii Dicot

Stenogyne campanulata (ncn) Stenogyne campanulata E Hawaii Dicot

Stenogyne kanehoana (ncn) Stenogyne kanehoana E Hawaii Dicot

Tetramolopium arenarium (ncn) Tetramolopium arenarium E Hawaii Dicot

Tetramolopium capillare (ncn) Tetramolopium capillare E Hawaii Dicot

Tetramolopium filiforme (ncn) Tetramolopium filiforme E Hawaii Dicot

Tetramolopium lepidotum ssp. lepidotum (ncn) Tetramolopium lepidotum ssp. lepidotum E Hawaii Dicot

Tetramolopium remyi (ncn) Tetramolopium remyi E Hawaii Dicot

Trematolobelia singularis (ncn) Trematolobelia singularis E Hawaii Dicot

Uhiuhi (Caesalpinia kavaiensis) Caesalpinia kavaiense E Hawaii Dicot

Vetch, Hawaiian (Vicia menziesii) Vicia menziesii E Hawaii Dicot

Vigna o

- wahuensis (ncn) Vigna o

- wahuensis E Hawaii Dicot

Viola helenae (ncn) Viola helenae E Hawaii Dicot

Viola oahuensis (ncn) Viola oahuensis E Hawaii Dicot

### 248 INVNAME SCINAME Status STATE

NAME Taxon

Wahine Noho Kula (Isodendrion pyrifolium) Isodendrion pyrifolium E Hawaii Dicot

Xylosma crenatum (ncn) Xylosma crenatum E Hawaii Dicot

Aupaka (Isodendrion longifolium) Isodendrion longifolium T Hawaii Dicot

Haha (Cyanea recta) Cyanea recta T Hawaii Dicot

Ha'Iwale (Cyrtandra limahuliensis) Cyrtandra limahuliensis T Hawaii Dicot

Kolea (Myrsine linearifolia) Myrsine linearifolia T Hawaii Dicot

Makou (Peucedanum sandwicense) Peucedanum sandwicense T Hawaii Dicot

Schiedea spergulina var. spergulina (ncn) Schiedea spergulina var. spergulina T Hawaii Dicot

Silene hawaiiensis (ncn) Silene hawaiiensis T Hawaii Dicot

Silversword, Haleakala ('Ahinahina) Argyroxiphium sandwicense ssp. macrocephalum T Hawaii Dicot

Tetramolopium rockii (ncn) Tetramolopium rockii T Hawaii Dicot

(ncn) Diellia mannii E Hawaii Ferns

(ncn) Doryopteris angelica E Hawaii Ferns

(ncn) Doryopteris takeuchii E Hawaii Ferns

Asplenium fragile var. insulare (ncn) Asplenium fragile var.

insulare E Hawaii Ferns

aumakua, Palapalai Dryopteris crinalis podosorus E Hawaii Ferns

Diellia erecta (ncn) Diellia erecta E Hawaii Ferns

Diellia falcata (ncn) Diellia falcata E Hawaii Ferns

Diellia pallida (ncn) Diellia pallida E Hawaii Ferns

Diellia unisora (ncn) Diellia unisora E Hawaii Ferns

### 249 INVNAME SCINAME Status STATE

NAME Taxon

Diplazium molokaiense (ncn) Diplazium molokaiense E Hawaii Ferns

Fern, Pendant Kihi (Adenophorus periens) Adenophorus periens E Hawaii Ferns

'Ihi'Ihi (Marsilea villosa) Marsilea villosa E Hawaii Ferns

Pauoa (Ctenitis squamigera) Ctenitis squamigera E Hawaii Ferns

Pteris lidgatei (ncn) Pteris lidgatei E Hawaii Ferns

Wawae'Iole (Phlegmariurus (=Huperzia) mannii) Huperzia mannii E Hawaii Ferns

Wawae'Iole (Phlegmariurus (=Lycopodium) nutans) Lycopodium (=Phlegmariurus) nutans E Hawaii Ferns

Snail, O'ahu Tree (Achatinella abbreviata) Achatinella abbreviata E Hawaii Gastropod

Snail, O'ahu Tree (Achatinella apexfulva) Achatinella apexfulva E Hawaii Gastropod

Snail, O'ahu Tree (Achatinella bellula) Achatinella bellula E Hawaii Gastropod

Snail, O'ahu Tree (Achatinella buddii) Achatinella buddii E Hawaii Gastropod

Snail, O'ahu Tree (Achatinella bulimoides) Achatinella bulimoides E Hawaii Gastropod

Snail, O'ahu Tree (Achatinella byronii) Achatinella byronii E Hawaii Gastropod

Snail, O'ahu Tree (Achatinella caesia) Achatinella caesia E Hawaii Gastropod

Snail, O'ahu Tree (Achatinella casta) Achatinella casta E Hawaii Gastropod

Snail, O'ahu Tree (Achatinella cestus) Achatinella cestus E Hawaii Gastropod

### 250 INVNAME SCINAME Status STATE

NAME Taxon

Snail, O'ahu Tree (Achatinella concavospira) Achatinella concavospira E Hawaii Gastropod

Snail, O'ahu Tree (Achatinella curta) Achatinella curta E Hawaii Gastropod

Snail, O'ahu Tree (Achatinella decipiens) Achatinella decipiens E Hawaii Gastropod

Snail, O'ahu Tree (Achatinella decora) Achatinella decora E Hawaii Gastropod

Snail, O'ahu Tree (Achatinella dimorpha) Achatinella dimorpha E Hawaii Gastropod

Snail, O'ahu Tree (Achatinella elegans) Achatinella elegans E Hawaii Gastropod

Snail, O'ahu Tree (Achatinella fulgens) Achatinella fulgens E Hawaii Gastropod

Snail, O'ahu Tree (Achatinella fuscobasis) Achatinella fuscobasis E Hawaii Gastropod

Snail, O'ahu Tree (Achatinella juddii) Achatinella juddii E Hawaii Gastropod

Snail, O'ahu Tree (Achatinella juncea) Achatinella juncea E Hawaii Gastropod

Snail, O'ahu Tree (Achatinella lehuiensis) Achatinella lehuiensis E Hawaii Gastropod

Snail, O'ahu Tree (Achatinella leucorraphe) Achatinella leucorraphe E Hawaii Gastropod

Snail, O'ahu Tree (Achatinella lila) Achatinella lila E Hawaii Gastropod

Snail, O'ahu Tree (Achatinella livida) Achatinella livida E Hawaii Gastropod

Snail, O'ahu Tree (Achatinella lorata) Achatinella lorata E Hawaii Gastropod

### 251 INVNAME SCINAME Status STATE

NAME Taxon

Snail, O'ahu Tree (Achatinella mustelina) Achatinella mustelina E Hawaii Gastropod

Snail, O'ahu Tree (Achatinella papyracea) Achatinella papyracea E Hawaii Gastropod

Snail, O'ahu Tree (Achatinella phaeozona) Achatinella phaeozona E Hawaii Gastropod

Snail, O'ahu Tree (Achatinella pulcherrima) Achatinella pulcherrima E Hawaii Gastropod

Snail, O'ahu Tree (Achatinella pupukanioe) Achatinella pupukanioe E Hawaii Gastropod

Snail, O'ahu Tree (Achatinella rosea) Achatinella rosea E Hawaii Gastropod

Snail, O'ahu Tree (Achatinella sowerbyana) Achatinella sowerbyana E Hawaii Gastropod

Snail, O'ahu Tree (Achatinella spaldingi) Achatinella spaldingi E Hawaii Gastropod

Snail, O'ahu Tree (Achatinella stewartii) Achatinella stewartii E Hawaii Gastropod

Snail, O'ahu Tree (Achatinella swiftii) Achatinella swiftii E Hawaii Gastropod

Snail, O'ahu Tree (Achatinella taeniolata) Achatinella taeniolata E Hawaii Gastropod

Snail, O'ahu Tree (Achatinella thaanumi) Achatinella thaahumi E Hawaii Gastropod

Snail, O'ahu Tree (Achatinella turgida) Achatinella turgida E Hawaii Gastropod

Snail, O'ahu Tree (Achatinella valida) Achatinella valida E Hawaii Gastropod

### 252 INVNAME SCINAME Status STATE

NAME Taxon

Snail, O'ahu Tree (Achatinella viridans) Achatinella viridans E Hawaii Gastropod

Snail, O'ahu Tree (Achatinella vittata) Achatinella vittata E Hawaii Gastropod

Snail, O'ahu Tree (Achatinella vulpina) Achatinella vulpina E Hawaii Gastropod

Snail, Newcomb's Erinna newcombi T Hawaii Gastropod

blackline Hawaiian damselfly Megalagrion nigrohamatum nigrolineatum E Hawaii Insect

Crimson Hawaiian damselfly Megalagrion leptodemas E Hawaii Insect

Damselfly, Flying Earwig Hawaiian Megalagrion nesiotes E Hawaii Insect

Damselfly, Pacific

Hawaiian Megalagrion pacificum E Hawaii Insect

Fly, Hawaiian picture

wing Drosophila aglaia E Hawaii Insect

Fly, Hawaiian picture

wing Drosophila hemipeza E Hawaii Insect

Fly, Hawaiian picture

wing Drosophila heteroneura E Hawaii Insect

Fly, Hawaiian picture

wing Drosophila montgomeryi E Hawaii Insect

Fly, Hawaiian picture

wing Drosophila musaphilia E Hawaii Insect

Fly, Hawaiian picture

wing Drosophila neoclavisetae E Hawaii Insect

Fly, Hawaiian picture

wing Drosophila obatai E Hawaii Insect

Fly, Hawaiian picture

wing Drosophila ochrobasis E Hawaii Insect

Fly, Hawaiian picture

wing Drosophila substenoptera E Hawaii Insect

Fly, Hawaiian picture

wing Drosophila tarphytrichia E Hawaii Insect

Hawaiian picture

- wing Fly Drosophila sharpi E Hawaii Insect

### 253 INVNAME SCINAME Status STATE

NAME Taxon

Moth, Blackburn's Sphinx Manduca blackburni E Hawaii Insect

Oceanic Hawaiian damselfly Megalagrion oceanicum E Hawaii Insect

Fly, Hawaiian picture

wing Drosophila mulli T Hawaii Insect

Bat, Hawaiian Hoary Lasiurus cinereus semotus E Hawaii Mammal

Seal, Hawaiian Monk Monachus schauinslandi E Hawaii Mammal

Whale, Humpback Megaptera novaeangliae E Hawaii Mammal

Whale, Sperm Physeter catodon (=macrocephalus) E Hawaii Mammal

Bluegrass, Hawaiian Poa sandvicensis E Hawaii Monocot

Bluegrass, Mann's (Poa mannii) Poa mannii E Hawaii Monocot

Grass, Fosberg's Love Eragrostis fosbergii E Hawaii Monocot

Hala Pepe (Pleomele hawaiiensis) Pleomele hawaiiensis E Hawaii Monocot

Hilo Ischaemum (Ischaemum byrone) Ischaemum byrone E Hawaii Monocot

Kamanomano (Cenchrus agrimonioides) Cenchrus agrimonioides E Hawaii Monocot

Lau'ehu (Panicum niihauense) Panicum niihauense E Hawaii Monocot

lo`ulu Pritchardia hardyi E Hawaii Monocot

Lo`ulu (Pritchardia affinis) Pritchardia affinis E Hawaii Monocot

Lo`ulu (Pritchardia kaalae) Pritchardia kaalae E Hawaii Monocot

Lo`ulu (Pritchardia napaliensis) Pritchardia napaliensis E Hawaii Monocot

Lo`ulu (Pritchardia schattaueri) Pritchardia schattaueri E Hawaii Monocot

### 254 INVNAME SCINAME Status STATE

NAME Taxon

Lo`ulu (Pritchardia viscosa) Pritchardia viscosa E Hawaii Monocot

Mariscus fauriei (ncn) Mariscus fauriei E Hawaii Monocot

Mariscus pennatiformis (ncn) Mariscus pennatiformis E Hawaii Monocot

Pa'iniu Astelia waialealae E Hawaii Monocot

Panicgrass, Carter's (Panicum fauriei var.carteri) Panicum fauriei var. carteri E Hawaii Monocot

Platanthera holochila (ncn) Platanthera holochila E Hawaii Monocot

Poa siphonoglossa (ncn) Poa siphonoglossa E Hawaii Monocot

Pu'uka'a (Cyperus trachysanthos) Cyperus trachysanthos E Hawaii Monocot

Sea turtle, hawksbill Eretmochelys imbricata E Hawaii Reptile

Sea turtle, leatherback Dermochelys coriacea E Hawaii Reptile

Sea turtle, green Chelonia mydas E/T Hawaii Reptile

Sea turtle, loggerhead Caretta caretta E/T Hawaii Reptile

Sea turtle, olive ridley Lepidochelys olivacea T Hawaii Reptile

Catchfly, Spalding's Silene spaldingii T Idaho Dicot

Four

- o'clock,

Macfarlane's Mirabilis macfarlanei T Idaho Dicot

Howellia, Water Howellia aquatilis T Idaho Dicot

Peppergrass, Slick Spot Lepidium papilliferum T Idaho Dicot

Salmon, Sockeye Oncorhynchus (=Salmo)

nerka E Idaho Fish

Sturgeon, White Acipenser transmontanus E Idaho Fish

Salmon, Chinook Oncorhynchus (=Salmo) tshawytscha E/T Idaho Fish

Steelhead Oncorhynchus (=Salmo) mykiss E/T Idaho Fish

### 255 INVNAME SCINAME Status STATE

NAME Taxon

Trout, Bull Salvelinus confluentus T Idaho Fish

Limpet, Banbury Springs Lanx sp. E Idaho Gastropod

Snail, Snake River Physa Physa natricina E Idaho Gastropod

Springsnail, Bruneau

Hot Pyrgulopsis bruneauensis E Idaho Gastropod

Snail, Bliss Rapids Taylorconcha serpenticola T Idaho Gastropod

Caribou, Woodland Rangifer tarandus caribou E Idaho Mammal

Bear, Grizzly Ursus arctos horribilis T Idaho Mammal

Lynx, Canada Lynx canadensis T Idaho Mammal

Squirrel, Northern

Idaho Ground Spermophilus brunneus

brunneus T Idaho Mammal

Ladies'

- tresses, Ute Spiranthes diluvialis T Idaho Monocot

Tern, Interior (population) Least Sterna antillarum E Illinois Bird

Plover, Piping Charadrius melodus E/T Illinois Bird

Fanshell Cyprogenia stegaria E Illinois Bivalve

Mucket, Pink (Pearlymussel) Lampsilis abrupta E Illinois Bivalve

Mussel, Clubshell Pleurobema clava E Illinois Bivalve

Mussel, snuffbox Epioblasma triquetra E Illinois Bivalve

Pearlymussel, Fat

Pocketbook Potamilus capax E Illinois Bivalve

Pearlymussel, Higgins' Eye Lampsilis higginsii E Illinois Bivalve

Pearlymussel, Orange

footed Plethobasus cooperianus E Illinois Bivalve

Sheepnose mussel Plethobasus cyphyus E Illinois Bivalve

Spectaclecase mussel Cumberlandia monodonta E Illinois Bivalve

Amphipod, Illinois

Cave Gammarus acherondytes E Illinois Crustacean

Clover, Leafy Prairie Dalea foliosa E Illinois Dicot

### 256 INVNAME SCINAME Status STATE

NAME Taxon

Aster, Decurrent False Boltonia decurrens T Illinois Dicot

Clover, Prairie Bush Lespedeza leptostachya T Illinois Dicot

Daisy, Lakeside Hymenoxys herbacea T Illinois Dicot

Milkweed, Mead's Asclepias meadii T Illinois Dicot

Potato

- bean, Price's Apios priceana T Illinois Dicot

Thistle, Pitcher's Cirsium pitcheri T Illinois Dicot

Sturgeon, Pallid Scaphirhynchus albus E Illinois Fish

Snail, Iowa

Pleistocene Discus macclintocki E Illinois Gastropod

Butterfly, Karner Blue Lycaeides melissa samuelis E Illinois Insect

Dragonfly, Hine's

Emerald Somatochlora hineana E Illinois Insect

Bat, Gray Myotis grisescens E Illinois Mammal

Bat, Indiana Myotis sodalis E Illinois Mammal

Orchid, Eastern Prairie Fringed Platanthera leucophaea T Illinois Monocot

Pogonia, Small

Whorled Isotria medeoloides T Illinois Monocot

Tern, Interior (population) Least Sterna antillarum E Indiana Bird

Fanshell Cyprogenia stegaria E Indiana Bivalve

Mucket, Pink (Pearlymussel) Lampsilis abrupta E Indiana Bivalve

Mussel, Clubshell Pleurobema clava E Indiana Bivalve

Mussel, Rough Pigtoe Pleurobema plenum E Indiana Bivalve

Mussel, snuffbox Epioblasma triquetra E Indiana Bivalve

Pearlymussel, Fat

Pocketbook Potamilus capax E Indiana Bivalve

Pearlymussel, White

Cat's Paw Epioblasma obliquata perobliqua E Indiana Bivalve

Rayed Bean Villosa fabalis E Indiana Bivalve

Riffleshell, Northern Epioblasma torulosa rangiana E Indiana Bivalve

### 257 INVNAME SCINAME Status STATE

NAME Taxon

Sheepnose mussel Plethobasus cyphyus E Indiana Bivalve

Clover, Running

Buffalo Trifolium stoloniferum E Indiana Dicot

Goldenrod, Short's Solidago shortii E Indiana Dicot

Milkweed, Mead's Asclepias meadii T Indiana Dicot

Thistle, Pitcher's Cirsium pitcheri T Indiana Dicot

Butterfly, Karner Blue Lycaeides melissa samuelis E Indiana Insect

Butterfly, Mitchell's Satyr Neonympha mitchellii

mitchellii E Indiana Insect

Bat, Gray Myotis grisescens E Indiana Mammal

Bat, Indiana Myotis sodalis E Indiana Mammal

Orchid, Eastern Prairie Fringed Platanthera leucophaea T Indiana Monocot

Snake, Northern Copperbelly Water Nerodia erythrogaster neglecta T Indiana Reptile

Tern, Interior (population) Least Sterna antillarum E Iowa Bird

Plover, Piping Charadrius melodus E/T Iowa Bird

Mussel, Dwarf Wedge Alasmidonta heterodon E Iowa Bivalve

Pearlymussel, Higgins' Eye Lampsilis higginsii E Iowa Bivalve

Sheepnose mussel Plethobasus cyphyus E Iowa Bivalve

Spectaclecase mussel Cumberlandia monodonta E Iowa Bivalve

Clover, Prairie Bush Lespedeza leptostachya T Iowa Dicot

Milkweed, Mead's Asclepias meadii T Iowa Dicot

Monkshood, Northern

Wild Aconitum noveboracense T Iowa Dicot

Shiner, Topeka Notropis topeka (=tristis) E Iowa Fish

Sturgeon, Pallid Scaphirhynchus albus E Iowa Fish

Snail, Iowa

Pleistocene Discus macclintocki E Iowa Gastropod

Bat, Indiana Myotis sodalis E Iowa Mammal

### 258 INVNAME SCINAME Status STATE

NAME Taxon

Orchid, Eastern Prairie Fringed Platanthera leucophaea T Iowa Monocot

Orchid, Western Prairie Fringed Platanthera praeclara T Iowa Monocot

Crane, Whooping Grus americana E Kansas Bird

Tern, Interior (population) Least Sterna antillarum E Kansas Bird

Plover, Piping Charadrius melodus E/T Kansas Bird

Spectaclecase mussel Cumberlandia monodonta E Kansas Bivalve

Milkweed, Mead's Asclepias meadii T Kansas Dicot

Shiner, Topeka Notropis topeka (=tristis) E Kansas Fish

Sturgeon, Pallid Scaphirhynchus albus E Kansas Fish

Madtom, Neosho Noturus placidus T Kansas Fish

Shiner, Arkansas River Notropis girardi T Kansas Fish

Beetle, American Burying Nicrophorus americanus E Kansas Insect

Bat, Gray Myotis grisescens E Kansas Mammal

Ferret, Black

- footed Mustela nigripes E Kansas Mammal

Orchid, Western Prairie Fringed Platanthera praeclara T Kansas Monocot

Tern, Interior (population) Least Sterna antillarum E Kentucky Bird

Warbler (=Wood),

Kirtland's Dendroica kirtlandii E Kentucky Bird

Warbler, Bachman's Vermivora bachmanii E Kentucky Bird

Woodpecker, Ivory

billed Campephilus principalis E Kentucky Bird

Woodpecker, Red

cockaded Picoides borealis E Kentucky Bird

Plover, Piping Charadrius melodus E/T Kentucky Bird

Fanshell Cyprogenia stegaria E Kentucky Bivalve

Mucket, Pink (Pearlymussel) Lampsilis abrupta E Kentucky Bivalve

Mussel, Clubshell Pleurobema clava E Kentucky Bivalve

### 259 INVNAME SCINAME Status STATE

NAME Taxon

Mussel, Cumberland

Combshell Epioblasma brevidens E Kentucky Bivalve

Mussel, Cumberland

Elktoe Alasmidonta atropurpurea E Kentucky Bivalve

Mussel, Oyster Epioblasma capsaeformis E Kentucky Bivalve

Mussel, Ring Pink (=Golf Stick Pearly) Obovaria retusa E Kentucky Bivalve

Mussel, Rough Pigtoe Pleurobema plenum E Kentucky Bivalve

Mussel, snuffbox Epioblasma triquetra E Kentucky Bivalve

Mussel, Winged Mapleleaf Quadrula fragosa E Kentucky Bivalve

Pearlymussel, Appalachian Monkeyface Quadrula sparsa E Kentucky Bivalve

Pearlymussel, Cracking Hemistena lata E Kentucky Bivalve

Pearlymussel,

Cumberland Bean Villosa trabalis E Kentucky Bivalve

Pearlymussel, Dromedary Dromus dromas E Kentucky Bivalve

Pearlymussel, Fat

Pocketbook Potamilus capax E Kentucky Bivalve

Pearlymussel, Little

wing Pegias fabula E Kentucky Bivalve

Pearlymussel, Orange

footed Plethobasus cooperianus E Kentucky Bivalve

Pearlymussel, Purple

Cat's Paw Epioblasma obliquata obliquata E Kentucky Bivalve

Pearlymussel,

Tubercled

- blossom Epioblasma torulosa

torulosa E Kentucky Bivalve

Pearlymussel, White Wartyback Plethobasus cicatricosus E Kentucky Bivalve

Pearlymussel, Yellow

blossom Epioblasma florentina florentina E Kentucky Bivalve

Riffleshell, Northern Epioblasma torulosa rangiana E Kentucky Bivalve

### 260 INVNAME SCINAME Status STATE

NAME Taxon

Riffleshell, Tan Epioblasma florentina walkeri (=E. walkeri) E Kentucky Bivalve

Sheepnose mussel Plethobasus cyphyus E Kentucky Bivalve

Shrimp, Kentucky

Cave Palaemonias ganteri E Kentucky Crustacean

Chaffseed, American Schwalbea americana E Kentucky Dicot

Clover, Running

Buffalo Trifolium stoloniferum E Kentucky Dicot

Goldenrod, Short's Solidago shortii E Kentucky Dicot

Rock

- cress, Small Arabis perstellata E. L. Braun var. perstellata

Fernald E Kentucky Dicot

Sandwort, Cumberland Arenaria cumberlandensis E Kentucky Dicot

Goldenrod, White

haired Solidago albopilosa T Kentucky Dicot

Potato

- bean, Price's Apios priceana T Kentucky Dicot

Rosemary,

Cumberland Conradina verticillata T Kentucky Dicot

Spiraea, Virginia Spiraea virginiana T Kentucky Dicot

Cumberland darter Etheostoma susanae E Kentucky Fish

Darter, Relict Etheostoma chienense E Kentucky Fish

Shiner, Palezone Notropis albizonatus E Kentucky Fish

Sturgeon, Pallid Scaphirhynchus albus E Kentucky Fish

Dace, Blackside Phoxinus cumberlandensis T Kentucky Fish

Beetle, American Burying Nicrophorus americanus E Kentucky Insect

Bat, Gray Myotis grisescens E Kentucky Mammal

Bat, Indiana Myotis sodalis E Kentucky Mammal

Bat, Virginia Big

eared Corynorhinus (=Plecotus) townsendii virginianus E Kentucky Mammal

Wolf, Red Canis rufus E Kentucky Mammal

### 261 INVNAME SCINAME Status STATE

NAME Taxon

Tern, Interior (population) Least Sterna antillarum E Louisiana Bird

Woodpecker, Red

cockaded Picoides borealis E Louisiana Bird

Plover, Piping Charadrius melodus E/T Louisiana Bird

Mucket, Pink (Pearlymussel) Lampsilis abrupta E Louisiana Bivalve

Mussel, Heelsplitter

Inflated Potamilus inflatus T Louisiana Bivalve

Pearlshell, Louisiana Margaritifera hembeli T Louisiana Bivalve

Chaffseed, American Schwalbea americana E Louisiana Dicot

Fruit, Earth (=geocarpon) Geocarpon minimum T Louisiana Dicot

Quillwort, Louisiana Isoetes louisianensis E Louisiana Ferns

Sturgeon, Pallid Scaphirhynchus albus E Louisiana Fish

Sturgeon, Gulf Acipenser oxyrinchus

desotoi T Louisiana Fish

Manatee, West Indian Trichechus manatus E Louisiana Mammal

Whale, Blue Balaenoptera musculus E Louisiana Mammal

Bear, Louisiana Black Ursus americanus luteolus T Louisiana Mammal

Sea turtle, hawksbill Eretmochelys imbricata E Louisiana Reptile

Sea turtle, Kemp's ridley Lepidochelys kempii E Louisiana Reptile

Sea turtle, leatherback Dermochelys coriacea E Louisiana Reptile

Sea turtle, green Chelonia mydas E/T Louisiana Reptile

Sea turtle, loggerhead Caretta caretta E/T Louisiana Reptile

Tortoise, Gopher Gopherus polyphemus T Louisiana Reptile

Turtle, Ringed Map Graptemys oculifera T Louisiana Reptile

Plover, Piping Charadrius melodus E/T Maine Bird

### 262 INVNAME SCINAME Status STATE

NAME Taxon

Tern, Roseate Sterna dougallii dougallii E/T Maine Bird

Lousewort, Furbish Pedicularis furbishiae E Maine Dicot

Salmon, Atlantic Salmo salar E Maine Fish

Sturgeon, Shortnose Acipenser brevirostrum E Maine Fish

Whale, Blue Balaenoptera musculus E Maine Mammal

Lynx, Canada Lynx canadensis T Maine Mammal

Orchid, Eastern Prairie Fringed Platanthera leucophaea T Maine Monocot

Pogonia, Small

Whorled Isotria medeoloides T Maine Monocot

Sea turtle, hawksbill Eretmochelys imbricata E Maine Reptile

Sea turtle, leatherback Dermochelys coriacea E Maine Reptile

Sea turtle, green Chelonia mydas E/T Maine Reptile

Sea turtle, loggerhead Caretta caretta E/T Maine Reptile

Plover, Piping Charadrius melodus E/T Maryland Bird

Mussel, Dwarf Wedge Alasmidonta heterodon E Maryland Bivalve

Dropwort, Canby's Oxypolis canbyi E Maryland Dicot

Gerardia, Sandplain Agalinis acuta E Maryland Dicot

Harperella Ptilimnium nodosum E Maryland Dicot

Amaranth, Seabeach Amaranthus pumilus T Maryland Dicot

Joint

- vetch, Sensitive Aeschynomene virginica T Maryland Dicot

Darter, Maryland Etheostoma sellare E Maryland Fish

Beetle, Northeastern Beach Tiger Cicindela dorsalis dorsalis T Maryland Insect

Beetle, Puritan Tiger Cicindela puritana T Maryland Insect

Bat, Indiana Myotis sodalis E Maryland Mammal

Squirrel, Delmarva

Peninsula Fox Sciurus niger cinereus E Maryland Mammal

### 263 INVNAME SCINAME Status STATE

NAME Taxon

Whale, Blue Balaenoptera musculus E Maryland Mammal

Bulrush, Northeastern (=Barbed Bristle) Scirpus ancistrochaetus E Maryland Monocot

Pink, Swamp Helonias bullata T Maryland Monocot

Sea turtle, hawksbill Eretmochelys imbricata E Maryland Reptile

Sea turtle, Kemp's ridley Lepidochelys kempii E Maryland Reptile

Sea turtle, leatherback Dermochelys coriacea E Maryland Reptile

Sea turtle, green Chelonia mydas E/T Maryland Reptile

Sea turtle, loggerhead Caretta caretta E/T Maryland Reptile

Turtle, Bog Clemmys muhlenbergii T Maryland Reptile

Plover, Piping Charadrius melodus E/T Massachusetts Bird

Tern, Roseate Sterna dougallii dougallii E/T Massachusetts Bird

Mussel, Dwarf Wedge Alasmidonta heterodon E Massachusetts Bivalve

Gerardia, Sandplain Agalinis acuta E Massachusetts Dicot

Sturgeon, Shortnose Acipenser brevirostrum E Massachusetts Fish

Beetle, American Burying Nicrophorus americanus E Massachusetts Insect

Beetle, Northeastern Beach Tiger Cicindela dorsalis dorsalis T Massachusetts Insect

Beetle, Puritan Tiger Cicindela puritana T Massachusetts Insect

Bat, Indiana Myotis sodalis E Massachusetts Mammal

Puma (=Cougar),

Eastern Puma (=Felis) concolor (all subsp. except coryi) E Massachusetts Mammal

Whale, Blue Balaenoptera musculus E Massachusetts Mammal

### 264 INVNAME SCINAME Status STATE

NAME Taxon

Bulrush, Northeastern (=Barbed Bristle) Scirpus ancistrochaetus E Massachusetts Monocot

Pogonia, Small

Whorled Isotria medeoloides T Massachusetts Monocot

Sea turtle, hawksbill Eretmochelys imbricata E Massachusetts Reptile

Sea turtle, Kemp's ridley Lepidochelys kempii E Massachusetts Reptile

Sea turtle, leatherback Dermochelys coriacea E Massachusetts Reptile

Turtle, Plymouth Red

bellied Pseudemys rubriventris bangsi E Massachusetts Reptile

Sea turtle, green Chelonia mydas E/T Massachusetts Reptile

Sea turtle, loggerhead Caretta caretta E/T Massachusetts Reptile

Turtle, Bog Clemmys muhlenbergii T Massachusetts Reptile

Warbler (=Wood),

Kirtland's Dendroica kirtlandii E Michigan Bird

Plover, Piping Charadrius melodus E/T Michigan Bird

Mussel, Clubshell Pleurobema clava E Michigan Bivalve

Mussel, snuffbox Epioblasma triquetra E Michigan Bivalve

Rayed Bean Villosa fabalis E Michigan Bivalve

Riffleshell, Northern Epioblasma torulosa rangiana E Michigan Bivalve

Monkey

- flower, Michigan Mimulus glabratus var. michiganensis E Michigan Dicot

Daisy, Lakeside Hymenoxys herbacea T Michigan Dicot

Goldenrod, Houghton's Solidago houghtonii T Michigan Dicot

Thistle, Pitcher's Cirsium pitcheri T Michigan Dicot

Fern, American hart's

tongue Asplenium scolopendrium

var. americanum T Michigan Ferns

Beetle, Hungerford's Crawling Water Brychius hungerfordi E Michigan Insect

### 265 INVNAME SCINAME Status STATE

NAME Taxon

Butterfly, Karner Blue Lycaeides melissa samuelis E Michigan Insect

Butterfly, Mitchell's Satyr Neonympha mitchellii

mitchellii E Michigan Insect

Dragonfly, Hine's

Emerald Somatochlora hineana E Michigan Insect

Bat, Indiana Myotis sodalis E Michigan Mammal

Gray Wolf Canis lupus E Michigan Mammal

Lynx, Canada Lynx canadensis T Michigan Mammal

Iris, Dwarf Lake Iris lacustris T Michigan Monocot

Orchid, Eastern Prairie Fringed Platanthera leucophaea T Michigan Monocot

Pogonia, Small

Whorled Isotria medeoloides T Michigan Monocot

Snake, Northern Copperbelly Water Nerodia erythrogaster neglecta T Michigan Reptile

Plover, Piping Charadrius melodus E/T Minnesota Bird

Mussel, snuffbox Epioblasma triquetra E Minnesota Bivalve

Mussel, Winged Mapleleaf Quadrula fragosa E Minnesota Bivalve

Pearlymussel, Higgins' Eye Lampsilis higginsii E Minnesota Bivalve

Sheepnose mussel Plethobasus cyphyus E Minnesota Bivalve

Spectaclecase mussel Cumberlandia monodonta E Minnesota Bivalve

Clover, Prairie Bush Lespedeza leptostachya T Minnesota Dicot

Roseroot, Leedy's Sedum integrifolium ssp. leedyi T Minnesota Dicot

Shiner, Topeka Notropis topeka (=tristis) E Minnesota Fish

Butterfly, Karner Blue Lycaeides melissa samuelis E Minnesota Insect

Lynx, Canada Lynx canadensis T Minnesota Mammal

Lily, Minnesota Trout Erythronium propullans E Minnesota Monocot

### 266 INVNAME SCINAME Status STATE

NAME Taxon

Orchid, Western Prairie Fringed Platanthera praeclara T Minnesota Monocot

Frog, Dusky Gopher (Mississippi DPS) Rana capito sevosa E Mississippi Amphibian

Crane, Mississippi

Sandhill Grus canadensis pulla E Mississippi Bird

Tern, Interior (population) Least Sterna antillarum E Mississippi Bird

Woodpecker, Red

cockaded Picoides borealis E Mississippi Bird

Plover, Piping Charadrius melodus E/T Mississippi Bird

Combshell, Southern (=Penitent mussel) Epioblasma penita E Mississippi Bivalve

Mussel, Black (=Curtus' Mussel)

Clubshell Pleurobema curtum E Mississippi Bivalve

Mussel, Cumberland

Combshell Epioblasma brevidens E Mississippi Bivalve

Mussel, Heavy Pigtoe (=Judge Tait's Mussel) Pleurobema taitianum E Mississippi Bivalve

Mussel, Ovate

Clubshell Pleurobema perovatum E Mississippi Bivalve

Mussel, snuffbox Epioblasma triquetra E Mississippi Bivalve

Mussel, Southern

Clubshell Pleurobema decisum E Mississippi Bivalve

Pearlymussel, Fat

Pocketbook Potamilus capax E Mississippi Bivalve

Mucket, Orange

- nacre Lampsilis perovalis T Mississippi Bivalve

Mussel, Alabama

Moccasinshell Medionidus acutissimus T Mississippi Bivalve

Mussel, Heelsplitter

Inflated Potamilus inflatus T Mississippi Bivalve

Pondberry Lindera melissifolia E Mississippi Dicot

### 267 INVNAME SCINAME Status STATE

NAME Taxon

Potato

- bean, Price's Apios priceana T Mississippi Dicot

Quillwort, Louisiana Isoetes louisianensis E Mississippi Ferns

Sturgeon, Pallid Scaphirhynchus albus E Mississippi Fish

Darter, Bayou Etheostoma rubrum T Mississippi Fish

Sturgeon, Gulf Acipenser oxyrinchus

desotoi T Mississippi Fish

Bat, Gray Myotis grisescens E Mississippi Mammal

Bat, Indiana Myotis sodalis E Mississippi Mammal

Manatee, West Indian Trichechus manatus E Mississippi Mammal

Whale, Blue Balaenoptera musculus E Mississippi Mammal

Bear, Louisiana Black Ursus americanus luteolus T Mississippi Mammal

Sea turtle, hawksbill Eretmochelys imbricata E Mississippi Reptile

Sea turtle, Kemp's ridley Lepidochelys kempii E Mississippi Reptile

Sea turtle, leatherback Dermochelys coriacea E Mississippi Reptile

Turtle, Alabama Red

bellied Pseudemys alabamensis E Mississippi Reptile

Sea turtle, green Chelonia mydas E/T Mississippi Reptile

Sea turtle, loggerhead Caretta caretta E/T Mississippi Reptile

Snake, Eastern Indigo Drymarchon corais couperi T Mississippi Reptile

Tortoise, Gopher Gopherus polyphemus T Mississippi Reptile

Turtle, Ringed Map Graptemys oculifera T Mississippi Reptile

Turtle, Yellow

blotched Map Graptemys flavimaculata T Mississippi Reptile

### 268 INVNAME SCINAME Status STATE

NAME Taxon

Ozark Hellbender Cryptobranchus alleganiensis bishopi E Missouri Amphibian

Tern, Interior (population) Least Sterna antillarum E Missouri Bird

Mucket, Pink (Pearlymussel) Lampsilis abrupta E Missouri Bivalve

Mussel, Scaleshell Leptodea leptodon E Missouri Bivalve

Mussel, snuffbox Epioblasma triquetra E Missouri Bivalve

Mussel, Winged Mapleleaf Quadrula fragosa E Missouri Bivalve

Pearlymussel, Curtis' Epioblasma florentina

curtisii E Missouri Bivalve

Pearlymussel, Fat

Pocketbook Potamilus capax E Missouri Bivalve

Pearlymussel, Higgins' Eye Lampsilis higginsii E Missouri Bivalve

Sheepnose mussel Plethobasus cyphyus E Missouri Bivalve

Spectaclecase mussel Cumberlandia monodonta E Missouri Bivalve

Clover, Running

Buffalo Trifolium stoloniferum E Missouri Dicot

Pondberry Lindera melissifolia E Missouri Dicot

Aster, Decurrent False Boltonia decurrens T Missouri Dicot

Bladderpod, Missouri Lesquerella filiformis T Missouri Dicot

Fruit, Earth (=geocarpon) Geocarpon minimum T Missouri Dicot

Milkweed, Mead's Asclepias meadii T Missouri Dicot

Sneezeweed, Virginia Helenium virginicum T Missouri Dicot

Shiner, Topeka Notropis topeka (=tristis) E Missouri Fish

Sturgeon, Pallid Scaphirhynchus albus E Missouri Fish

Cavefish, Ozark Amblyopsis rosae T Missouri Fish

Darter, Niangua Etheostoma nianguae T Missouri Fish

Madtom, Neosho Noturus placidus T Missouri Fish

### 269 INVNAME SCINAME Status STATE

NAME Taxon

Cavesnail, Tumbling

Creek Antrobia culveri E Missouri Gastropod

Dragonfly, Hine's

Emerald Somatochlora hineana E Missouri Insect

Bat, Gray Myotis grisescens E Missouri Mammal

Bat, Indiana Myotis sodalis E Missouri Mammal

Orchid, Western Prairie Fringed Platanthera praeclara T Missouri Monocot

Crane, Whooping Grus americana E Montana Bird

Tern, Interior (population) Least Sterna antillarum E Montana Bird

Plover, Piping Charadrius melodus E/T Montana Bird

Catchfly, Spalding's Silene spaldingii T Montana Dicot

Howellia, Water Howellia aquatilis T Montana Dicot

Sturgeon, Pallid Scaphirhynchus albus E Montana Fish

Sturgeon, White Acipenser transmontanus E Montana Fish

Trout, Bull Salvelinus confluentus T Montana Fish

Ferret, Black

- footed Mustela nigripes E Montana Mammal

Bear, Grizzly Ursus arctos horribilis T Montana Mammal

Lynx, Canada Lynx canadensis T Montana Mammal

Ladies'

- tresses, Ute Spiranthes diluvialis T Montana Monocot

Crane, Whooping Grus americana E Nebraska Bird

Curlew, Eskimo Numenius borealis E Nebraska Bird

Tern, Interior (population) Least Sterna antillarum E Nebraska Bird

Plover, Piping Charadrius melodus E/T Nebraska Bird

Penstemon, Blowout Penstemon haydenii E Nebraska Dicot

Butterfly Plant,

Colorado Gaura neomexicana var.

coloradensis T Nebraska Dicot

Shiner, Topeka Notropis topeka (=tristis) E Nebraska Fish

Sturgeon, Pallid Scaphirhynchus albus E Nebraska Fish

### 270 INVNAME SCINAME Status STATE

NAME Taxon

Beetle, American Burying Nicrophorus americanus E Nebraska Insect

Beetle, Salt Creek Tiger Cicindela nevadica

lincolniana E Nebraska Insect

Ferret, Black

- footed Mustela nigripes E Nebraska Mammal

Gray Wolf Canis lupus E Nebraska Mammal

Ladies'

- tresses, Ute Spiranthes diluvialis T Nebraska Monocot

Orchid, Western Prairie Fringed Platanthera praeclara T Nebraska Monocot

Flycatcher,

Southwestern Willow Empidonax traillii extimus E Nevada Bird

Rail, Yuma Clapper Rallus longirostris yumanensis E Nevada Bird

Buckwheat, Steamboat Eriogonum ovalifolium var.

williamsiae E Nevada Dicot

Niterwort, Amargosa Nitrophila mohavensis E Nevada Dicot

Poolfish, Pahrump (= Pahrump Killifish) Empetrichthys latos E Nevada Dicot

Blazing Star, Ash

Meadows Mentzelia leucophylla T Nevada Dicot

Centaury, Spring

loving Centaurium namophilum T Nevada Dicot

Gumplant, Ash

Meadows Grindelia fraxino

- pratensis T Nevada Dicot

Ivesia, Ash Meadows Ivesia kingii var. eremica T Nevada Dicot

Milk

- vetch, Ash

Meadows Astragalus phoenix T Nevada Dicot

Sunray, Ash Meadows Enceliopsis nudicaulis var.

corrugata T Nevada Dicot

Chub, Humpback Gila cypha E Nevada Fish

Chub, Pahranagat

Roundtail Gila robusta jordani E Nevada Fish

Chub, Virgin River Gila seminuda (=robusta) E Nevada Fish

### 271 INVNAME SCINAME Status STATE

NAME Taxon

Cui

- ui Chasmistes cujus E Nevada Fish

Dace, Ash Meadows Speckled Rhinichthys osculus

nevadensis E Nevada Fish

Dace, Clover Valley Speckled Rhinichthys osculus oligoporus E Nevada Fish

Dace, Independence Valley Speckled Rhinichthys osculus lethoporus E Nevada Fish

Dace, Moapa Moapa coriacea E Nevada Fish

Pupfish, Ash Meadows Amargosa Cyprinodon nevadensis

mionectes E Nevada Fish

Pupfish, Devils Hole Cyprinodon diabolis E Nevada Fish

Pupfish, Warm Springs Cyprinodon nevadensis pectoralis E Nevada Fish

Spinedace, White

River Lepidomeda albivallis E Nevada Fish

Springfish, Hiko

White River Crenichthys baileyi grandis E Nevada Fish

Springfish, White

River Crenichthys baileyi baileyi E Nevada Fish

Sucker, Razorback Xyrauchen texanus E Nevada Fish

Woundfin Plagopterus argentissimus E Nevada Fish

Dace, Desert Eremichthys acros T Nevada Fish

Spinedace, Big Spring Lepidomeda mollispinis pratensis T Nevada Fish

Springfish, Railroad Valley Crenichthys nevadae T Nevada Fish

Sucker, Warner Catostomus warnerensis T Nevada Fish

Trout, Bull Salvelinus confluentus T Nevada Fish

Trout, Lahontan

Cutthroat Oncorhynchus clarki

henshawi T Nevada Fish

Skipper, Carson Wandering Pseudocopaeodes eunus

obscurus E Nevada Insect

Naucorid, Ash

Meadows Ambrysus amargosus T Nevada Insect

### 272 INVNAME SCINAME Status STATE

NAME Taxon

Gray Wolf Canis lupus E Nevada Mammal

Ladies'

- tresses, Ute Spiranthes diluvialis T Nevada Monocot

Tortoise, Desert Gopherus agassizii T Nevada Reptile

Plover, Piping Charadrius melodus E/T New Hampshire Bird

Mussel, Dwarf Wedge Alasmidonta heterodon E New Hampshire Bivalve

Milk

- vetch, Jesup's Astragalus robbinsii var. jesupi E New Hampshire Dicot

Butterfly, Karner Blue Lycaeides melissa samuelis E New Hampshire Insect

Whale, Blue Balaenoptera musculus E New Hampshire Mammal

Lynx, Canada Lynx canadensis T New Hampshire Mammal

Bulrush, Northeastern (=Barbed Bristle) Scirpus ancistrochaetus E New Hampshire Monocot

Pogonia, Small

Whorled Isotria medeoloides T New Hampshire Monocot

Sea turtle, hawksbill Eretmochelys imbricata E New Hampshire Reptile

Sea turtle, leatherback Dermochelys coriacea E New Hampshire Reptile

Sea turtle, green Chelonia mydas E/T New Hampshire Reptile

Sea turtle, loggerhead Caretta caretta E/T New Hampshire Reptile

Plover, Piping Charadrius melodus E/T New Jersey Bird

### 273 INVNAME SCINAME Status STATE

NAME Taxon

Tern, Roseate Sterna dougallii dougallii E/T New Jersey Bird

Mussel, Dwarf Wedge Alasmidonta heterodon E New Jersey Bivalve

Chaffseed, American Schwalbea americana E New Jersey Dicot

Amaranth, Seabeach Amaranthus pumilus T New Jersey Dicot

Joint

- vetch, Sensitive Aeschynomene virginica T New Jersey Dicot

Beetle, Northeastern Beach Tiger Cicindela dorsalis dorsalis T New Jersey Insect

Bat, Indiana Myotis sodalis E New Jersey Mammal

Whale, Blue Balaenoptera musculus E New Jersey Mammal

Beaked

- rush,

Knieskern's Rhynchospora knieskernii T New Jersey Monocot

Pink, Swamp Helonias bullata T New Jersey Monocot

Pogonia, Small

Whorled Isotria medeoloides T New Jersey Monocot

Sea turtle, hawksbill Eretmochelys imbricata E New Jersey Reptile

Sea turtle, Kemp's ridley Lepidochelys kempii E New Jersey Reptile

Sea turtle, leatherback Dermochelys coriacea E New Jersey Reptile

Sea turtle, green Chelonia mydas E/T New Jersey Reptile

Sea turtle, loggerhead Caretta caretta E/T New Jersey Reptile

Turtle, Bog Clemmys muhlenbergii T New Jersey Reptile

Frog, Chiricahua Leopard Rana chiricahuensis T New Mexico Amphibian

Falcon, Northern Aplomado Falco femoralis septentrionalis E New Mexico Bird

### 274 INVNAME SCINAME Status STATE

NAME Taxon

Flycatcher,

Southwestern Willow Empidonax traillii extimus E New Mexico Bird

Tern, Interior (population) Least Sterna antillarum E New Mexico Bird

Plover, Piping Charadrius melodus E/T New Mexico Bird

Owl, Mexican Spotted Strix occidentalis lucida T New Mexico Bird

Amphipod, Noel's Gammarus desperatus E New Mexico Crustacean

Isopod, Socorro Thermosphaeroma thermophilus E New Mexico Crustacean

Cactus, Knowlton Pediocactus knowltonii E New Mexico Dicot

Cactus, Kuenzler Hedgehog Echinocereus fendleri var.
kuenzleri E New Mexico Dicot

Cactus, Sneed

Pincushion Coryphantha sneedii var.

sneedii E New Mexico Dicot

Ipomopsis, Holy Ghost Ipomopsis sancti

- spiritus E New Mexico Dicot

Milk

- vetch, Mancos Astragalus humillimus E New Mexico Dicot

Pennyroyal, Todsen's Hedeoma todsenii E New Mexico Dicot

Poppy, Sacramento Prickly Argemone pleiacantha ssp. pinnatisecta E New Mexico Dicot

Cactus, Lee

Pincushion Coryphantha sneedii var.

leei T New Mexico Dicot

Cactus, Mesa Verde Sclerocactus mesae

- verdae T New Mexico Dicot

Fleabane, Zuni Erigeron rhizomatus T New Mexico Dicot

Sunflower, Pecos Helianthus paradoxus T New Mexico Dicot

Thistle, Sacramento

Mountains Cirsium vinaceum T New Mexico Dicot

Wild

- buckwheat, Gypsum Eriogonum gypsophilum T New Mexico Dicot

### 275 INVNAME SCINAME Status STATE

NAME Taxon

Chub, Gila Gila intermedia E New Mexico Fish

Gambusia, Pecos Gambusia nobilis E New Mexico Fish

Minnow, Loach Tiaroga cobitis E New Mexico Fish

Minnow, Rio Grande Silvery Hybognathus amarus E New Mexico Fish

Spikedace Meda fulgida E New Mexico Fish

Squawfish, Colorado Ptychocheilus lucius E New Mexico Fish

Sucker, Razorback Xyrauchen texanus E New Mexico Fish

Topminnow, Gila (Yaqui) Poeciliopsis occidentalis E New Mexico Fish

Trout, Gila Oncorhynchus gilae E New Mexico Fish

Chub, Chihuahua Gila nigrescens T New Mexico Fish

Shiner, Arkansas River Notropis girardi T New Mexico Fish

Shiner, Beautiful Cyprinella formosa T New Mexico Fish

Shiner, Pecos

Bluntnose Notropis simus pecosensis T New Mexico Fish

Snail, Pecos

Assiminea Assiminea pecos E New Mexico Gastropod

Springsnail, Alamosa Tryonia alamosae E New Mexico Gastropod

Springsnail, Chupadera Pyrgulopsis chupaderae E New Mexico Gastropod

Springsnail, Koster's Juturnia kosteri E New Mexico Gastropod

Springsnail, Roswell Pyrgulopsis roswellensis E New Mexico Gastropod

Springsnail, Socorro Pyrgulopsis neomexicana E New Mexico Gastropod

Bat, Lesser (=Sanborn's) Long

nosed Leptonycteris curasoae yerbabuenae E New Mexico Mammal

### 276 INVNAME SCINAME Status STATE

NAME Taxon

Bat, Mexican Long

nosed Leptonycteris nivalis E New Mexico Mammal

Ferret, Black

- footed Mustela nigripes E New Mexico Mammal

Gray Wolf Canis lupus E New Mexico Mammal

Jaguar Panthera onca E New Mexico Mammal

Rattlesnake, New Mexican Ridge

- nosed Crotalus willardi obscurus T New Mexico Reptile

Plover, Piping Charadrius melodus E/T New York Bird

Tern, Roseate Sterna dougallii dougallii E/T New York Bird

Mussel, Clubshell Pleurobema clava E New York Bivalve

Mussel, Dwarf Wedge Alasmidonta heterodon E New York Bivalve

Rayed Bean Villosa fabalis E New York Bivalve

Gerardia, Sandplain Agalinis acuta E New York Dicot

Amaranth, Seabeach Amaranthus pumilus T New York Dicot

Goldenrod, Houghton's Solidago houghtonii T New York Dicot

Monkshood, Northern

Wild Aconitum noveboracense T New York Dicot

Roseroot, Leedy's Sedum integrifolium ssp. leedyi T New York Dicot

Fern, American hart's

tongue Asplenium scolopendrium

var. americanum T New York Ferns

Sturgeon, Shortnose Acipenser brevirostrum E New York Fish

Snail, Chittenango

Ovate Amber Succinea chittenangoensis T New York Gastropod

Butterfly, Karner Blue Lycaeides melissa samuelis E New York Insect

### 277 INVNAME SCINAME Status STATE

NAME Taxon

Bat, Indiana Myotis sodalis E New York Mammal

Whale, Blue Balaenoptera musculus E New York Mammal

Orchid, Eastern Prairie Fringed Platanthera leucophaea T New York Monocot

Pogonia, Small

Whorled Isotria medeoloides T New York Monocot

Sea turtle, hawksbill Eretmochelys imbricata E New York Reptile

Sea turtle, Kemp's ridley Lepidochelys kempii E New York Reptile

Sea turtle, leatherback Dermochelys coriacea E New York Reptile

Sea turtle, green Chelonia mydas E/T New York Reptile

Sea turtle, loggerhead Caretta caretta E/T New York Reptile

Turtle, Bog Clemmys muhlenbergii T New York Reptile

Spider, Spruce

- fir

Moss Microhexura montivaga E North

Carolina Arachnid

Stork, Wood Mycteria americana E North

Carolina Bird

Woodpecker, Red

cockaded Picoides borealis E North

Carolina Bird

Plover, Piping Charadrius melodus E/T North

Carolina Bird

Tern, Roseate Sterna dougallii dougallii E/T North

Carolina Bird

Elktoe, Appalachian Alasmidonta raveneliana E North

Carolina Bivalve

Mussel, Dwarf Wedge Alasmidonta heterodon E North

Carolina Bivalve

Mussel, Heelsplitter

Carolina Lasmigona decorata E North

Carolina Bivalve

Pearlymussel,

Cumberland Bean Villosa trabalis E North

Carolina Bivalve

Pearlymussel, Little

wing Pegias fabula E North

Carolina Bivalve

### 278 INVNAME SCINAME Status STATE

NAME Taxon

Riffleshell, Tan Epioblasma florentina walkeri (=E. walkeri) E North

Carolina Bivalve

Spinymussel, James

River Pleurobema collina E North

Carolina Bivalve

Spinymussel, Tar

River Elliptio steinstansana E North

Carolina Bivalve

Avens, Spreading Geum radiatum E North

Carolina Dicot

Bittercress, Small

anthered Cardamine micranthera E North

Carolina Dicot

Bluet, Roan Mountain Hedyotis purpurea var.

montana E North

Carolina Dicot

Chaffseed, American Schwalbea americana E North

Carolina Dicot

Coneflower, Smooth Echinacea laevigata E North

Carolina Dicot

Dropwort, Canby's Oxypolis canbyi E North

Carolina Dicot

Harperella Ptilimnium nodosum E North

Carolina Dicot

Loosestrife, Rough

leaved Lysimachia asperulaefolia E North

Carolina Dicot

Meadowrue, Cooley's Thalictrum cooleyi E North

Carolina Dicot

Pitcher

- plant, Green Sarracenia oreophila E North

Carolina Dicot

Pitcher

- plant,

Mountain Sweet Sarracenia rubra ssp. jonesii E North

Carolina Dicot

Pondberry Lindera melissifolia E North

Carolina Dicot

Sumac, Michaux's Rhus michauxii E North

Carolina Dicot

Sunflower,

Schweinitz's Helianthus schweinitzii E North

Carolina Dicot

Amaranth, Seabeach Amaranthus pumilus T North

Carolina Dicot

Blazing Star, Heller's Liatris helleri T North

Carolina Dicot

Goldenrod, Blue Ridge Solidago spithamaea T North

Carolina Dicot

### 279 INVNAME SCINAME Status STATE

NAME Taxon

Heartleaf, Dwarf

flowered Hexastylis naniflora T North

Carolina Dicot

Heather, Mountain

Golden Hudsonia montana T North

Carolina Dicot

Joint

- vetch, Sensitive Aeschynomene virginica T North

Carolina Dicot

Spiraea, Virginia Spiraea virginiana T North

Carolina Dicot

Logperch, Roanoke Percina rex E North

Carolina Fish

Shiner, Cape Fear Notropis mekistocholas E North

Carolina Fish

Sturgeon, Shortnose Acipenser brevirostrum E North

Carolina Fish

Chub, Spotfin Erimonax monachus T North

Carolina Fish

Silverside, Waccamaw Menidia extensa T North

Carolina Fish

Snail, Noonday Mesodon clarki nantahala T North

Carolina Gastropod

Butterfly, Saint Francis' Satyr Neonympha mitchellii francisci E North

Carolina Insect

Lichen, Rock Gnome Gymnoderma lineare E North

Carolina Lichen

Bat, Gray Myotis grisescens E North

Carolina Mammal

Bat, Indiana Myotis sodalis E North

Carolina Mammal

Bat, Virginia Big

eared Corynorhinus (=Plecotus) townsendii virginianus E North

Carolina Mammal

Manatee, West Indian Trichechus manatus E North

Carolina Mammal

Puma (=Cougar),

Eastern Puma (=Felis) concolor (all subsp. except coryi) E North

Carolina Mammal

Squirrel, Carolina Northern Flying Glaucomys sabrinus

coloratus E North

Carolina Mammal

Whale, Blue Balaenoptera musculus E North

Carolina Mammal

### 280 INVNAME SCINAME Status STATE

NAME Taxon

Wolf, Red Canis rufus E North

Carolina Mammal

Arrowhead, Bunched Sagittaria fasciculata E North

Carolina Monocot

Irisette, White Sisyrinchium dichotomum E North

Carolina Monocot

Sedge, Golden Carex lutea E North

Carolina Monocot

Pink, Swamp Helonias bullata T North

Carolina Monocot

Pogonia, Small

Whorled Isotria medeoloides T North

Carolina Monocot

Sea turtle, hawksbill Eretmochelys imbricata E North

Carolina Reptile

Sea turtle, Kemp's ridley Lepidochelys kempii E North

Carolina Reptile

Sea turtle, leatherback Dermochelys coriacea E North

Carolina Reptile

Sea turtle, green Chelonia mydas E/T North

Carolina Reptile

Sea turtle, loggerhead Caretta caretta E/T North

Carolina Reptile

Alligator, American Alligator mississippiensis T North

Carolina Reptile

Turtle, Bog Clemmys muhlenbergii T North

Carolina Reptile

Crane, Whooping Grus americana E North Dakota Bird

Tern, Interior (population) Least Sterna antillarum E North Dakota Bird

Plover, Piping Charadrius melodus E/T North Dakota Bird

Sturgeon, Pallid Scaphirhynchus albus E North Dakota Fish

Ferret, Black

- footed Mustela nigripes E North Dakota Mammal

Gray Wolf Canis lupus E North Dakota Mammal

Orchid, Western Prairie Fringed Platanthera praeclara T North Dakota Monocot

### 281 INVNAME SCINAME Status STATE

NAME Taxon

Crow, Mariana Corvus kubaryi E Northern

Mariana

Islands Bird

Megapode, Micronesian (La Perouse's) Megapodius laperouse E Northern

Mariana

Islands Bird

Moorhen, Mariana

Common Gallinula chloropus guami E Northern

Mariana

Islands Bird

Warbler, nightingale reed (old world warbler) Acrocephalus luscinia E Northern

Mariana

Islands Bird

White

- eye, Rota

Bridled Zosterops rotensis E Northern

Mariana

Islands Bird

Bat, Mariana Fruit (=Mariana Flying Fox) Pteropus mariannus

mariannus T Northern

Mariana

Islands Mammal

Plover, Piping Charadrius melodus E/T Ohio Bird

Fanshell Cyprogenia stegaria E Ohio Bivalve

Mucket, Pink (Pearlymussel) Lampsilis abrupta E Ohio Bivalve

Mussel, Clubshell Pleurobema clava E Ohio Bivalve

Mussel, snuffbox Epioblasma triquetra E Ohio Bivalve

Pearlymussel, Purple

Cat's Paw Epioblasma obliquata obliquata E Ohio Bivalve

Pearlymussel, White

Cat's Paw Epioblasma obliquata perobliqua E Ohio Bivalve

Rayed Bean Villosa fabalis E Ohio Bivalve

Riffleshell, Northern Epioblasma torulosa rangiana E Ohio Bivalve

Sheepnose mussel Plethobasus cyphyus E Ohio Bivalve

Clover, Running

Buffalo Trifolium stoloniferum E Ohio Dicot

Daisy, Lakeside Hymenoxys herbacea T Ohio Dicot

Monkshood, Northern

Wild Aconitum noveboracense T Ohio Dicot

Spiraea, Virginia Spiraea virginiana T Ohio Dicot

Madtom, Scioto Noturus trautmani E Ohio Fish

### 282 INVNAME SCINAME Status STATE

NAME Taxon

Beetle, American Burying Nicrophorus americanus E Ohio Insect

Butterfly, Karner Blue Lycaeides melissa samuelis E Ohio Insect

Butterfly, Mitchell's Satyr Neonympha mitchellii

mitchellii E Ohio Insect

Bat, Indiana Myotis sodalis E Ohio Mammal

Orchid, Eastern Prairie Fringed Platanthera leucophaea T Ohio Monocot

Pogonia, Small

Whorled Isotria medeoloides T Ohio Monocot

Snake, Northern Copperbelly Water Nerodia erythrogaster neglecta T Ohio Reptile

Crane, Whooping Grus americana E Oklahoma Bird

Curlew, Eskimo Numenius borealis E Oklahoma Bird

Tern, Interior (population) Least Sterna antillarum E Oklahoma Bird

Vireo, Black

- capped Vireo atricapilla E Oklahoma Bird

Woodpecker, Red

cockaded Picoides borealis E Oklahoma Bird

Plover, Piping Charadrius melodus E/T Oklahoma Bird

Mussel, Scaleshell Leptodea leptodon E Oklahoma Bivalve

Mussel, Winged Mapleleaf Quadrula fragosa E Oklahoma Bivalve

Rock

- pocketbook, Ouachita (=Wheeler's pm) Arkansia wheeleri E Oklahoma Bivalve

Cavefish, Ozark Amblyopsis rosae T Oklahoma Fish

Darter, Leopard Percina pantherina T Oklahoma Fish

Madtom, Neosho Noturus placidus T Oklahoma Fish

Shiner, Arkansas River Notropis girardi T Oklahoma Fish

### 283 INVNAME SCINAME Status STATE

NAME Taxon

Beetle, American Burying Nicrophorus americanus E Oklahoma Insect

Bat, Gray Myotis grisescens E Oklahoma Mammal

Bat, Indiana Myotis sodalis E Oklahoma Mammal

Bat, Ozark Big

- eared Corynorhinus (=Plecotus) townsendii ingens E Oklahoma Mammal

Orchid, Eastern Prairie Fringed Platanthera leucophaea T Oklahoma Monocot

Orchid, Western Prairie Fringed Platanthera praeclara T Oklahoma Monocot

Alligator, American Alligator mississippiensis T Oklahoma Reptile

Albatross, Short

- tailed Phoebastria (=Diomedea)

albatrus E Oregon Bird

Murrelet, Marbled Brachyramphus marmoratus T Oregon Bird

Owl, Northern Spotted Strix occidentalis caurina T Oregon Bird

Plover, Western Snowy Charadrius alexandrinus

nivosus T Oregon Bird

Fairy Shrimp, Vernal

Pool Branchinecta lynchi T Oregon Crustacean

Daisy, Willamette Erigeron decumbens var.

decumbens E Oregon Dicot

Lomatium, Bradshaw's Lomatium bradshawii E Oregon Dicot

Lomatium, Cook's Lomatium cookii E Oregon Dicot

Meadowfoam, Large

flowered Woolly Limnanthes floccosa ssp. Grandiflora E Oregon Dicot

Milk

- vetch, Applegate's Astragalus applegatei E Oregon Dicot

Popcornflower, Rough Plagiobothrys hirtus E Oregon Dicot

Rock

- cress, McDonald's Arabis mcdonaldiana E Oregon Dicot

### 2 84 INVNAME SCINAME Status STATE

NAME Taxon

Catchfly, Spalding's Silene spaldingii T Oregon Dicot

Checker

- mallow,

Nelson's Sidalcea nelsoniana T Oregon Dicot

Four

- o'clock,

Macfarlane's Mirabilis macfarlanei T Oregon Dicot

Howellia, Water Howellia aquatilis T Oregon Dicot

Lupine, Kincaid's Lupinus sulphureus (=oreganus) ssp. kincaidii (=var. kincaidii) T Oregon Dicot

Paintbrush, Golden Castilleja levisecta T Oregon Dicot

Thelypody, Howell's Spectacular Thelypodium howellii spectabilis T Oregon Dicot

Chub, Oregon Oregonichthys crameri E Oregon Fish

Salmon, Sockeye Oncorhynchus (=Salmo)

nerka E Oregon Fish

Sucker, Lost River Deltistes luxatus E Oregon Fish

Sucker, Modoc Catostomus microps E Oregon Fish

Sucker, Shortnose Chasmistes brevirostris E Oregon Fish

Salmon, Chinook Oncorhynchus (=Salmo) tshawytscha E/T Oregon Fish

Salmon, Coho Oncorhynchus (=Salmo)

kisutch E/T Oregon Fish

Steelhead Oncorhynchus (=Salmo) mykiss E/T Oregon Fish

Chub, Hutton Tui Gila bicolor ssp. T Oregon Fish

Dace, Foskett Speckled Rhinichthys osculus ssp. T Oregon Fish

Salmon, Chum Oncorhynchus (=Salmo)

keta T Oregon Fish

Sucker, Warner Catostomus warnerensis T Oregon Fish

Trout, Bull Salvelinus confluentus T Oregon Fish

Trout, Lahontan

Cutthroat Oncorhynchus clarki

henshawi T Oregon Fish

### 285 INVNAME SCINAME Status STATE

NAME Taxon

Butterfly, Fender's

Blue Icaricia icarioides fenderi E Oregon Insect

Butterfly, Oregon Silverspot Speyeria zerene hippolyta T Oregon Insect

Deer, Columbian

White

- tailed Odocoileus virginianus

leucurus E Oregon Mammal

Gray Wolf Canis lupus E Oregon Mammal

Whale, Blue Balaenoptera musculus E Oregon Mammal

Whale, Gray Eschrichtius robustus E Oregon Mammal

Lynx, Canada Lynx canadensis T Oregon Mammal

Fritillary, Gentner's Fritillaria gentneri E Oregon Monocot

Lily, Western Lilium occidentale E Oregon Monocot

Sea turtle, leatherback Dermochelys coriacea E Oregon Reptile

Sea turtle, green Chelonia mydas E/T Oregon Reptile

Sea turtle, loggerhead Caretta caretta E/T Oregon Reptile

Plover, Piping Charadrius melodus E/T Pennsylvania Bird

Mussel, Clubshell Pleurobema clava E Pennsylvania Bivalve

Mussel, Dwarf Wedge Alasmidonta heterodon E Pennsylvania Bivalve

Mussel, snuffbox Epioblasma triquetra E Pennsylvania Bivalve

Rayed Bean Villosa fabalis E Pennsylvania Bivalve

Riffleshell, Northern Epioblasma torulosa rangiana E Pennsylvania Bivalve

Sheepnose mussel Plethobasus cyphyus E Pennsylvania Bivalve

Bat, Indiana Myotis sodalis E Pennsylvania Mammal

Whale, Blue Balaenoptera musculus E Pennsylvania Mammal

Bulrush, Northeastern (=Barbed Bristle) Scirpus ancistrochaetus E Pennsylvania Monocot

### 286 INVNAME SCINAME Status STATE

NAME Taxon

Pogonia, Small

Whorled Isotria medeoloides T Pennsylvania Monocot

Turtle, Bog Clemmys muhlenbergii T Pennsylvania Reptile

Coqui, Golden Eleutherodactylus jasperi T Puerto Rico Amphibian

Guajon Eleutherodactylus cooki T Puerto Rico Amphibian

Toad, Puerto Rican

Crested Peltophryne lemur T Puerto Rico Amphibian

Blackbird, Yellow

shouldered Agelaius xanthomus E Puerto Rico Bird

Hawk, Puerto Rican

Broad

- winged Buteo platypterus

brunnescens E Puerto Rico Bird

Hawk, Puerto Rican Sharp

- shinned Accipiter striatus venator E Puerto Rico Bird

Nightjar, Puerto Rico Caprimulgus noctitherus E Puerto Rico Bird

Parrot, Puerto Rican Amazona vittata E Puerto Rico Bird

Pigeon, Puerto Rican

Plain Columba inornata wetmorei E Puerto Rico Bird

Plover, Piping Charadrius melodus E/T Puerto Rico Bird

Tern, Roseate Sterna dougallii dougallii E/T Puerto Rico Bird

Coral, Elkhorn Acropora palmata T Puerto Rico Coral

Coral, Staghorn Acropora cervicornis T Puerto Rico Coral

Auerodendron pauciflorum (ncn) Auerodendron pauciflorum E Puerto Rico Dicot

Bariaco Trichilia triacantha E Puerto Rico Dicot

Boxwood, Vahl's Buxus vahlii E Puerto Rico Dicot

Calyptranthes Thomasiana (ncn) Calyptranthes thomasiana E Puerto Rico Dicot

### 287 INVNAME SCINAME Status STATE

NAME Taxon

Capa Rosa Callicarpa ampla E Puerto Rico Dicot

Catesbaea Melanocarpa (ncn) Catesbaea melanocarpa E Puerto Rico Dicot

Chamaecrista glandulosa (ncn) Chamaecrista glandulosa

var. mirabilis E Puerto Rico Dicot

Chupacallos Pleodendron macranthum E Puerto Rico Dicot

Cordia bellonis (ncn) Cordia bellonis E Puerto Rico Dicot

Daphnopsis hellerana (ncn) Daphnopsis hellerana E Puerto Rico Dicot

Erubia Solanum drymophilum E Puerto Rico Dicot

Eugenia Woodburyana Eugenia woodburyana E Puerto Rico Dicot

Goetzea, Beautiful (Matabuey) Goetzea elegans E Puerto Rico Dicot

Higuero De Sierra Crescentia portoricensis E Puerto Rico Dicot

Holly, Cook's Ilex cookii E Puerto Rico Dicot

Ilex sintenisii (ncn) Ilex sintenisii E Puerto Rico Dicot

Leptocereus grantianus (ncn) Leptocereus grantianus E Puerto Rico Dicot

Lyonia truncata var. proctorii (ncn) Lyonia truncata var. proctorii E Puerto Rico Dicot

Mitracarpus

Maxwelliae Mitracarpus maxwelliae E Puerto Rico Dicot

Mitracarpus Polycladus Mitracarpus polycladus E Puerto Rico Dicot

Myrcia Paganii Myrcia paganii E Puerto Rico Dicot

Palo Colorado (Ternstroemia luquillensis) Ternstroemia luquillensis E Puerto Rico Dicot

Palo de Jazmin Styrax portoricensis E Puerto Rico Dicot

### 288 INVNAME SCINAME Status STATE

NAME Taxon

Palo de Nigua Cornutia obovata E Puerto Rico Dicot

Palo de Ramon Banara vanderbiltii E Puerto Rico Dicot

Palo de Rosa Ottoschulzia rhodoxylon E Puerto Rico Dicot

Peperomia, Wheeler's Peperomia wheeleri E Puerto Rico Dicot

Prickly

- ash, St.

Thomas Zanthoxylum thomasianum E Puerto Rico Dicot

Ternstroemia subsessilis (ncn) Ternstroemia subsessilis E Puerto Rico Dicot

Uvillo Eugenia haematocarpa E Puerto Rico Dicot

Vernonia Proctorii (ncn) Vernonia proctorii E Puerto Rico Dicot

Chumbo, Higo Harrisia portoricensis T Puerto Rico Dicot

Cobana Negra Stahlia monosperma T Puerto Rico Dicot

Gesneria pauciflora (ncn) Gesneria pauciflora T Puerto Rico Dicot

Schoepfia arenaria (ncn) Schoepfia arenaria T Puerto Rico Dicot

Fern, Adiantum vivesii Adiantum vivesii E Puerto Rico Ferns

Fern, Elaphoglossum

serpens Elaphoglossum serpens E Puerto Rico Ferns

Fern, Thelypteris

inabonensis Thelypteris inabonensis E Puerto Rico Ferns

Fern, Thelypteris

verecunda Thelypteris verecunda E Puerto Rico Ferns

Fern, Thelypteris yaucoensis Thelypteris yaucoensis E Puerto Rico Ferns

Polystichum calderonense (ncn) Polystichum calderonense E Puerto Rico Ferns

Tectaria Estremerana Tectaria estremerana E Puerto Rico Ferns

Tree Fern, Elfin Cyathea dryopteroides E Puerto Rico Ferns

### 289 INVNAME SCINAME Status STATE

NAME Taxon

Manatee, West Indian Trichechus manatus E Puerto Rico Mammal

Aristida chaseae (ncn) Aristida chaseae E Puerto Rico Monocot

Cranichis Ricartii Cranichis ricartii E Puerto Rico Monocot

Lepanthes eltorensis (ncn) Lepanthes eltoroensis E Puerto Rico Monocot

Pelos del Diablo Aristida portoricensis E Puerto Rico Monocot

Walnut, Nogal Juglans jamaicensis E Puerto Rico Monocot

Manaca, palma de Calyptronoma rivalis T Puerto Rico Monocot

Anole, Culebra Island

Giant Anolis roosevelti E Puerto Rico Reptile

Boa, Puerto Rican Epicrates inornatus E Puerto Rico Reptile

Boa, Virgin Islands

Tree Epicrates monensis granti E Puerto Rico Reptile

Sea turtle, hawksbill Eretmochelys imbricata E Puerto Rico Reptile

Sea turtle, leatherback Dermochelys coriacea E Puerto Rico Reptile

Sea turtle, green Chelonia mydas E/T Puerto Rico Reptile

Sea turtle, loggerhead Caretta caretta E/T Puerto Rico Reptile

Plover, Piping Charadrius melodus E/T Rhode Island Bird

Tern, Roseate Sterna dougallii dougallii E/T Rhode Island Bird

Gerardia, Sandplain Agalinis acuta E Rhode Island Dicot

Sturgeon, Shortnose Acipenser brevirostrum E Rhode Island Fish

Beetle, American Burying Nicrophorus americanus E Rhode Island Insect

Puma (=Cougar),

Eastern Puma (=Felis) concolor (all subsp. except coryi) E Rhode Island Mammal

### 290 INVNAME SCINAME Status STATE

NAME Taxon

Whale, Blue Balaenoptera musculus E Rhode Island Mammal

Pogonia, Small

Whorled Isotria medeoloides T Rhode Island Monocot

Sea turtle, hawksbill Eretmochelys imbricata E Rhode Island Reptile

Sea turtle, Kemp's ridley Lepidochelys kempii E Rhode Island Reptile

Sea turtle, leatherback Dermochelys coriacea E Rhode Island Reptile

Sea turtle, green Chelonia mydas E/T Rhode Island Reptile

Sea turtle, loggerhead Caretta caretta E/T Rhode Island Reptile

Salamander, Frosted

Flatwoods Ambystoma cingulatum T South

Carolina Amphibian

Stork, Wood Mycteria americana E South

Carolina Bird

Warbler (=Wood),

Kirtland's Dendroica kirtlandii E South

Carolina Bird

Warbler, Bachman's Vermivora bachmanii E South

Carolina Bird

Woodpecker, Red

cockaded Picoides borealis E South

Carolina Bird

Plover, Piping Charadrius melodus E/T South

Carolina Bird

Tern, Roseate Sterna dougallii dougallii E/T South

Carolina Bird

Mussel, Heelsplitter

Carolina Lasmigona decorata E South

Carolina Bivalve

Chaffseed, American Schwalbea americana E South

Carolina Dicot

Coneflower, Smooth Echinacea laevigata E South

Carolina Dicot

Dropwort, Canby's Oxypolis canbyi E South

Carolina Dicot

Harperella Ptilimnium nodosum E South

Carolina Dicot

Loosestrife, Rough

leaved Lysimachia asperulaefolia E South

Carolina Dicot

### 291 INVNAME SCINAME Status STATE

NAME Taxon

Pitcher

- plant,

Mountain Sweet Sarracenia rubra ssp. jonesii E South

Carolina Dicot

Pondberry Lindera melissifolia E South

Carolina Dicot

Sumac, Michaux's Rhus michauxii E South

Carolina Dicot

Sunflower,

Schweinitz's Helianthus schweinitzii E South

Carolina Dicot

Amaranth, Seabeach Amaranthus pumilus T South

Carolina Dicot

Amphianthus, Little Amphianthus pusillus T South

Carolina Dicot

Gooseberry,

Miccosukee Ribes echinellum T South

Carolina Dicot

Heartleaf, Dwarf

flowered Hexastylis naniflora T South

Carolina Dicot

Quillwort, Black

spored Isoetes melanospora E South

Carolina Ferns

Sturgeon, Shortnose Acipenser brevirostrum E South

Carolina Fish

Lichen, Rock Gnome Gymnoderma lineare E South

Carolina Lichen

Manatee, West Indian Trichechus manatus E South

Carolina Mammal

Whale, Blue Balaenoptera musculus E South

Carolina Mammal

Arrowhead, Bunched Sagittaria fasciculata E South

Carolina Monocot

Irisette, White Sisyrinchium dichotomum E South

Carolina Monocot

Trillium, Persistent Trillium persistens E South

Carolina Monocot

Trillium, Relict Trillium reliquum E South

Carolina Monocot

Pink, Swamp Helonias bullata T South

Carolina Monocot

Pogonia, Small

Whorled Isotria medeoloides T South

Carolina Monocot

Sea turtle, hawksbill Eretmochelys imbricata E South

Carolina Reptile

### 292 INVNAME SCINAME Status STATE

NAME Taxon

Sea turtle, Kemp's ridley Lepidochelys kempii E South

Carolina Reptile

Sea turtle, leatherback Dermochelys coriacea E South

Carolina Reptile

Sea turtle, green Chelonia mydas E/T South

Carolina Reptile

Sea turtle, loggerhead Caretta caretta E/T South

Carolina Reptile

Turtle, Bog Clemmys muhlenbergii T South

Carolina Reptile

Crane, Whooping Grus americana E South Dakota Bird

Curlew, Eskimo Numenius borealis E South Dakota Bird

Tern, Interior (population) Least Sterna antillarum E South Dakota Bird

Plover, Piping Charadrius melodus E/T South Dakota Bird

Mussel, Scaleshell Leptodea leptodon E South Dakota Bivalve

Pearlymussel, Higgins' Eye Lampsilis higginsii E South Dakota Bivalve

Shiner, Topeka Notropis topeka (=tristis) E South Dakota Fish

Sturgeon, Pallid Scaphirhynchus albus E South Dakota Fish

Beetle, American Burying Nicrophorus americanus E South Dakota Insect

Gray Wolf Canis lupus E South Dakota Mammal

Orchid, Western Prairie Fringed Platanthera praeclara T South Dakota Monocot

Spider, Spruce

- fir

Moss Microhexura montivaga E Tennessee Arachnid

Stork, Wood Mycteria americana E Tennessee Bird

Tern, Interior (population) Least Sterna antillarum E Tennessee Bird

Woodpecker, Red

cockaded Picoides borealis E Tennessee Bird

### 293 INVNAME SCINAME Status STATE

NAME Taxon

Combshell, Upland Epioblasma metastriata E Tennessee Bivalve

Elktoe, Appalachian Alasmidonta raveneliana E Tennessee Bivalve

Fanshell Cyprogenia stegaria E Tennessee Bivalve

Kidneyshell, Triangular Ptychobranchus greenii E Tennessee Bivalve

Mucket, Pink (Pearlymussel) Lampsilis abrupta E Tennessee Bivalve

Mussel, Clubshell Pleurobema clava E Tennessee Bivalve

Mussel, Coosa

Moccasinshell Medionidus parvulus E Tennessee Bivalve

Mussel, Cumberland

Combshell Epioblasma brevidens E Tennessee Bivalve

Mussel, Cumberland

Elktoe Alasmidonta atropurpurea E Tennessee Bivalve

Mussel, Cumberland Pigtoe Pleurobema gibberum E Tennessee Bivalve

Mussel, Fine

- rayed Pigtoe Fusconaia cuneolus E Tennessee Bivalve

Mussel, Georgia pigtoe Pleurobema hanleyianum E Tennessee Bivalve

Mussel, Ovate

Clubshell Pleurobema perovatum E Tennessee Bivalve

Mussel, Oyster Epioblasma capsaeformis E Tennessee Bivalve

Mussel, Ring Pink (=Golf Stick Pearly) Obovaria retusa E Tennessee Bivalve

Mussel, Rough Pigtoe Pleurobema plenum E Tennessee Bivalve

Mussel, Shiny Pigtoe Fusconaia cor E Tennessee Bivalve

Mussel, snuffbox Epioblasma triquetra E Tennessee Bivalve

Mussel, Southern Pigtoe Pleurobema georgianum E Tennessee Bivalve

Pearlymussel, Alabama Lamp Lampsilis virescens E Tennessee Bivalve

### 294 INVNAME SCINAME Status STATE

NAME Taxon

Pearlymussel, Appalachian Monkeyface Quadrula sparsa E Tennessee Bivalve

Pearlymussel, Birdwing Lemiox rimosus E Tennessee Bivalve

Pearlymussel, Cracking Hemistena lata E Tennessee Bivalve

Pearlymussel,

Cumberland Bean Villosa trabalis E Tennessee Bivalve

Pearlymussel,

Cumberland Monkeyface Quadrula intermedia E Tennessee Bivalve

Pearlymussel, Dromedary Dromus dromas E Tennessee Bivalve

Pearlymussel, Green

blossom Epioblasma torulosa gubernaculum E Tennessee Bivalve

Pearlymussel, Little

wing Pegias fabula E Tennessee Bivalve

Pearlymussel, Orange

footed Plethobasus cooperianus E Tennessee Bivalve

Pearlymussel, Pale Lilliput Toxolasma cylindrellus E Tennessee Bivalve

Pearlymussel, Purple

Cat's Paw Epioblasma obliquata obliquata E Tennessee Bivalve

Pearlymussel,

Tubercled

- blossom Epioblasma torulosa

torulosa E Tennessee Bivalve

Pearlymussel, Turgid

blossom Epioblasma turgidula E Tennessee Bivalve

Pearlymussel, White Wartyback Plethobasus cicatricosus E Tennessee Bivalve

Pearlymussel, Yellow

blossom Epioblasma florentina florentina E Tennessee Bivalve

Purple Bean Villosa perpurpurea E Tennessee Bivalve

Rabbitsfoot, Rough Quadrula cylindrica strigillata E Tennessee Bivalve

Riffleshell, Tan Epioblasma florentina walkeri (=E. walkeri) E Tennessee Bivalve

Sheepnose mussel Plethobasus cyphyus E Tennessee Bivalve

### 295 INVNAME SCINAME Status STATE

NAME Taxon

Spectaclecase mussel Cumberlandia monodonta E Tennessee Bivalve

Mussel, Alabama

Moccasinshell Medionidus acutissimus T Tennessee Bivalve

Mussel, Fine

- lined

Pocketbook Lampsilis altilis T Tennessee Bivalve

Crayfish, Nashville Orconectes shoupi E Tennessee Crustacean

Aster, Ruth's Golden Pityopsis ruthii E Tennessee Dicot

Avens, Spreading Geum radiatum E Tennessee Dicot

Bladderpod, Spring

Creek Lesquerella perforata E Tennessee Dicot

Bluet, Roan Mountain Hedyotis purpurea var.

montana E Tennessee Dicot

Chaffseed, American Schwalbea americana E Tennessee Dicot

Clover, Leafy Prairie Dalea foliosa E Tennessee Dicot

Ground

- plum,

Guthrie's Astragalus bibullatus E Tennessee Dicot

Pitcher

- plant, Green Sarracenia oreophila E Tennessee Dicot

Rock

- cress, Braun's Arabis perstellata E. L. Braun var. ampla Rollins E Tennessee Dicot

Sandwort, Cumberland Arenaria cumberlandensis E Tennessee Dicot

Goldenrod, Blue Ridge Solidago spithamaea T Tennessee Dicot

Potato

- bean, Price's Apios priceana T Tennessee Dicot

Rosemary,

Cumberland Conradina verticillata T Tennessee Dicot

Skullcap, Large

flowered Scutellaria montana T Tennessee Dicot

Spiraea, Virginia Spiraea virginiana T Tennessee Dicot

### 296 INVNAME SCINAME Status STATE

NAME Taxon

Fern, American hart's

tongue Asplenium scolopendrium

var. americanum T Tennessee Ferns

Chucky Madtom Noturus crypticus E Tennessee Fish

Cumberland darter Etheostoma susanae E Tennessee Fish

Darter, Amber Percina antesella E Tennessee Fish

Darter, Bluemask (=jewel) Etheostoma sp. E Tennessee Fish

Darter, Boulder Etheostoma wapiti E Tennessee Fish

Darter, Duskytail Etheostoma percnurum E Tennessee Fish

Laurel dace Chrosomus aylori E Tennessee Fish

Logperch, Conasauga Percina jenkinsi E Tennessee Fish

Madtom, Pygmy Noturus stanauli E Tennessee Fish

Madtom, Smoky Noturus baileyi E Tennessee Fish

Shiner, Palezone Notropis albizonatus E Tennessee Fish

Sturgeon, Pallid Scaphirhynchus albus E Tennessee Fish

Chub, Slender Erimystax cahni T Tennessee Fish

Chub, Spotfin Erimonax monachus T Tennessee Fish

Dace, Blackside Phoxinus cumberlandensis T Tennessee Fish

Darter, Slackwater Etheostoma boschungi T Tennessee Fish

Darter, Snail Percina tanasi T Tennessee Fish

Madtom, Yellowfin Noturus flavipinnis T Tennessee Fish

Shiner, Blue Cyprinella caerulea T Tennessee Fish

### 297 INVNAME SCINAME Status STATE

NAME Taxon

Marstonia, Royal (=Royal Snail) Pyrgulopsis ogmorhaphe E Tennessee Gastropod

Riversnail, Anthony's Athearnia anthonyi E Tennessee Gastropod

Snail, Painted Snake

Coiled Forest Anguispira picta T Tennessee Gastropod

Lichen, Rock Gnome Gymnoderma lineare E Tennessee Lichen

Bat, Gray Myotis grisescens E Tennessee Mammal

Bat, Indiana Myotis sodalis E Tennessee Mammal

Squirrel, Carolina Northern Flying Glaucomys sabrinus

coloratus E Tennessee Mammal

Grass, Tennessee

Yellow

- eyed Xyris tennesseensis E Tennessee Monocot

Pogonia, Small

Whorled Isotria medeoloides T Tennessee Monocot

Salamander, Barton Springs Eurycea sosorum E Texas Amphibian

Salamander, Texas

Blind Typhlomolge rathbuni E Texas Amphibian

Toad, Houston Bufo houstonensis E Texas Amphibian

Salamander, San

Marcos Eurycea nana T Texas Amphibian

Harvestman, Bee

Creek Cave Texella reddelli E Texas Arachnid

Harvestman, Bone

Cave Texella reyesi E Texas Arachnid

Harvestman, Cokendolpher Cave Texella cokendolpheri E Texas Arachnid

Meshweaver, Braken

Bat Cave Cicurina venii E Texas Arachnid

Meshweaver, Government Canyon

Bat Cave Cicurina vespera E Texas Arachnid

Meshweaver, Madla's

Cave Cicurina madla E Texas Arachnid

Meshweaver, Robber

Baron Cave Cicurina baronia E Texas Arachnid

### 298 INVNAME SCINAME Status STATE

NAME Taxon

Pseudoscorpion, Tooth

Cave Tartarocreagris texana E Texas Arachnid

Spider, Government Canyon Bat Cave Neoleptoneta microps E Texas Arachnid

Spider, Tooth Cave Leptoneta myopica E Texas Arachnid

Crane, Mississippi

Sandhill Grus canadensis pulla E Texas Bird

Crane, Whooping Grus americana E Texas Bird

Curlew, Eskimo Numenius borealis E Texas Bird

Falcon, Northern Aplomado Falco femoralis septentrionalis E Texas Bird

Flycatcher,

Southwestern Willow Empidonax traillii extimus E Texas Bird

Prairie

- chicken,

Attwater's Greater Tympanuchus cupido

attwateri E Texas Bird

Tern, Interior (population) Least Sterna antillarum E Texas Bird

Vireo, Black

- capped Vireo atricapilla E Texas Bird

Warbler (=Wood),

Golden

- cheeked Dendroica chrysoparia E Texas Bird

Woodpecker, Red

cockaded Picoides borealis E Texas Bird

Plover, Piping Charadrius melodus E/T Texas Bird

Owl, Mexican Spotted Strix occidentalis lucida T Texas Bird

Amphipod, Peck's

Cave Stygobromus (=Stygonectes) pecki E Texas Crustacean

Ambrosia, South

Texas Ambrosia cheiranthifolia E Texas Dicot

Ayenia, Texas Ayenia limitaris E Texas Dicot

Bladderpod, White Lesquerella pallida E Texas Dicot

Bladderpod, Zapata Lesquerella thamnophila E Texas Dicot

Cactus, Black Lace Echinocereus reichenbachii

var. albertii E Texas Dicot

Cactus, Nellie Cory Coryphantha minima E Texas Dicot

### 299 INVNAME SCINAME Status STATE

NAME Taxon

Cactus, Sneed

Pincushion Coryphantha sneedii var.

sneedii E Texas Dicot

Cactus, Star Astrophytum asterias E Texas Dicot

Cactus, Tobusch

Fishhook Ancistrocactus tobuschii E Texas Dicot

Cat's

- eye, Terlingua

Creek Cryptantha crassipes E Texas Dicot

Dawn

- flower, Texas Prairie (=Texas Bitterweed) Hymenoxys texana E Texas Dicot

Dogweed, Ashy Thymophylla tephroleuca E Texas Dicot

Frankenia, Johnston's Frankenia johnstonii E Texas Dicot

Manioc, Walker's Manihot walkerae E Texas Dicot

Phlox, Texas Trailing Phlox nivalis ssp. texensis E Texas Dicot

Pitaya, Davis' Green Echinocereus viridiflorus

var. davisii E Texas Dicot

Poppy

- mallow, Texas Callirhoe scabriuscula E Texas Dicot

Rush

- pea, Slender Hoffmannseggia tenella E Texas Dicot

Sand

- verbena, Large

fruited Abronia macrocarpa E Texas Dicot

Snowbells, Texas Styrax texanus E Texas Dicot

Cactus, Bunched Cory Coryphantha ramillosa T Texas Dicot

Cactus, Chisos Mountain Hedgehog Echinocereus chisoensis var.

chisoensis T Texas Dicot

Cactus, Lloyd's Mariposa Echinomastus mariposensis T Texas Dicot

Fruit, Earth (=geocarpon) Geocarpon minimum T Texas Dicot

Oak, Hinckley Quercus hinckleyi T Texas Dicot

Sunflower, Pecos Helianthus paradoxus T Texas Dicot

Darter, Fountain Etheostoma fonticola E Texas Fish

### 300 INVNAME SCINAME Status STATE

NAME Taxon

Gambusia, Big Bend Gambusia gaigei E Texas Fish

Gambusia, Clear

Creek Gambusia heterochir E Texas Fish

Gambusia, Pecos Gambusia nobilis E Texas Fish

Gambusia, San Marcos Gambusia georgei E Texas Fish

Pupfish, Comanche Springs Cyprinodon elegans E Texas Fish

Pupfish, Leon Springs Cyprinodon bovinus E Texas Fish

Minnow, Devils River Dionda diaboli T Texas Fish

Shiner, Arkansas River Notropis girardi T Texas Fish

Snail, Pecos

Assiminea Assiminea pecos E Texas Gastropod

Beetle, American Burying Nicrophorus americanus E Texas Insect

Beetle, Coffin Cave

Mold Batrisodes texanus E Texas Insect

Beetle, Comal Springs Dryopid Stygoparnus comalensis E Texas Insect

Beetle, Comal Springs

Riffle Heterelmis comalensis E Texas Insect

Beetle, Helotes Mold Batrisodes venyivi E Texas Insect

Beetle, Kretschmarr

Cave Mold Texamaurops reddelli E Texas Insect

Beetle, Tooth Cave

Ground Rhadine persephone E Texas Insect

Rhadine exilis (ncn) Rhadine exilis E Texas Insect

Rhadine infernalis (ncn) Rhadine infernalis E Texas Insect

Bat, Mexican Long

nosed Leptonycteris nivalis E Texas Mammal

Jaguarundi, Gulf Coast Herpailurus (=Felis) yagouaroundi cacomitli E Texas Mammal

### 301 INVNAME SCINAME Status STATE

NAME Taxon

Manatee, West Indian Trichechus manatus E Texas Mammal

Ocelot Leopardus (=Felis) pardalis E Texas Mammal

Whale, Blue Balaenoptera musculus E Texas Mammal

Bear, Louisiana Black Ursus americanus luteolus T Texas Mammal

Ladies'

- tresses,

Navasota Spiranthes parksii E Texas Monocot

Pondweed, Little Aguja Creek Potamogeton clystocarpus E Texas Monocot

Wild

- rice, Texas Zizania texana E Texas Monocot

Sea turtle, hawksbill Eretmochelys imbricata E Texas Reptile

Sea turtle, Kemp's ridley Lepidochelys kempii E Texas Reptile

Sea turtle, leatherback Dermochelys coriacea E Texas Reptile

Sea turtle, green Chelonia mydas E/T Texas Reptile

Sea turtle, loggerhead Caretta caretta E/T Texas Reptile

Condor, California Gymnogyps californianus E Utah Bird

Flycatcher,

Southwestern Willow Empidonax traillii extimus E Utah Bird

Owl, Mexican Spotted Strix occidentalis lucida T Utah Bird

Bearclaw poppy,

Dwarf Arctomecon humilis E Utah Dicot

Bladderpod,

Kodachrome Lesquerella tumulosa E Utah Dicot

Buttercup, Autumn Ranunculus aestivalis (=acriformis) E Utah Dicot

Cactus, San Rafael Pediocactus despainii E Utah Dicot

Cactus, Wright

Fishhook Sclerocactus wrightiae E Utah Dicot

### 302 INVNAME SCINAME Status STATE

NAME Taxon

Milk

- vetch, Holmgren Astragalus holmgreniorum E Utah Dicot

Milk

- vetch, Shivwits Astragalus ampullarioides E Utah Dicot

Phacelia, Clay Phacelia argillacea E Utah Dicot

Reed

- mustard, Barneby Schoenocrambe barnebyi E Utah Dicot

Reed

- mustard, Shrubby Schoenocrambe suffrutescens E Utah Dicot

Ridge

- cress (=Pepper

cress), Barneby Lepidium barnebyanum E Utah Dicot

Cactus, Colorado

hookless Sclerocactus glaucus T Utah Dicot

Cactus, Pariette Sclerocactus brevispinus T Utah Dicot

Cactus, Siler

Pincushion Pediocactus (=Echinocactus,=Utahia)

sileri T Utah Dicot

Cactus, Uinta Basin

hookless Sclerocactus wetlandicus T Utah Dicot

Cactus, Winkler Pediocactus winkleri T Utah Dicot

Cycladenia, Jones Cycladenia jonesii (=humilis) T Utah Dicot

Milk

- vetch, Deseret Astragalus desereticus T Utah Dicot

Milk

- vetch, Heliotrope Astragalus montii T Utah Dicot

Milkweed, Welsh's Asclepias welshii T Utah Dicot

Primrose, Maguire Primula maguirei T Utah Dicot

Reed

- mustard, Clay Schoenocrambe argillacea T Utah Dicot

Townsendia, Last

Chance Townsendia aprica T Utah Dicot

Chub, Bonytail Gila elegans E Utah Fish

Chub, Humpback Gila cypha E Utah Fish

Chub, Virgin River Gila seminuda (=robusta) E Utah Fish

Squawfish, Colorado Ptychocheilus lucius E Utah Fish

### 303 INVNAME SCINAME Status STATE

NAME Taxon

Sucker, June Chasmistes liorus E Utah Fish

Sucker, Razorback Xyrauchen texanus E Utah Fish

Woundfin Plagopterus argentissimus E Utah Fish

Trout, Lahontan

Cutthroat Oncorhynchus clarki

henshawi T Utah Fish

Ambersnail, Kanab Oxyloma haydeni

kanabensis E Utah Gastropod

Ferret, Black

- footed Mustela nigripes E Utah Mammal

Gray Wolf Canis lupus E Utah Mammal

Lynx, Canada Lynx canadensis T Utah Mammal

Prairie Dog, Utah Cynomys parvidens T Utah Mammal

Ladies'

- tresses, Ute Spiranthes diluvialis T Utah Monocot

Sedge, Navajo Carex specuicola T Utah Monocot

Tortoise, Desert Gopherus agassizii T Utah Reptile

Mussel, Dwarf Wedge Alasmidonta heterodon E Vermont Bivalve

Milk

- vetch, Jesup's Astragalus robbinsii var. jesupi E Vermont Dicot

Bat, Indiana Myotis sodalis E Vermont Mammal

Whale, Blue Balaenoptera musculus E Vermont Mammal

Lynx, Canada Lynx canadensis T Vermont Mammal

Bulrush, Northeastern (=Barbed Bristle) Scirpus ancistrochaetus E Vermont Monocot

Pogonia, Small

Whorled Isotria medeoloides T Vermont Monocot

Coral, Elkhorn Acropora palmata T Virgin Islands Coral

Coral, Staghorn Acropora cervicornis T Virgin Islands Coral

Boxwood, Vahl's Buxus vahlii E Virgin Islands Dicot

Catesbaea Melanocarpa (ncn) Catesbaea melanocarpa E Virgin Islands Dicot

Lizard, St. Croix

Ground Ameiva polops E Virgin Islands Reptile

### 304 INVNAME SCINAME Status STATE

NAME Taxon

Salamander,

Shenandoah Plethodon shenandoah E Virginia Amphibian

Spider, Spruce

- fir

Moss Microhexura montivaga E Virginia Arachnid

Woodpecker, Red

cockaded Picoides borealis E Virginia Bird

Plover, Piping Charadrius melodus E/T Virginia Bird

Tern, Roseate Sterna dougallii dougallii E/T Virginia Bird

Fanshell Cyprogenia stegaria E Virginia Bivalve

Mucket, Pink (Pearlymussel) Lampsilis abrupta E Virginia Bivalve

Mussel, Cumberland

Combshell Epioblasma brevidens E Virginia Bivalve

Mussel, Dwarf Wedge Alasmidonta heterodon E Virginia Bivalve

Mussel, Fine

- rayed Pigtoe Fusconaia cuneolus E Virginia Bivalve

Mussel, Oyster Epioblasma capsaeformis E Virginia Bivalve

Mussel, Rough Pigtoe Pleurobema plenum E Virginia Bivalve

Mussel, Shiny Pigtoe Fusconaia cor E Virginia Bivalve

Mussel, snuffbox Epioblasma triquetra E Virginia Bivalve

Pearlymussel, Appalachian Monkeyface Quadrula sparsa E Virginia Bivalve

Pearlymussel, Birdwing Lemiox rimosus E Virginia Bivalve

Pearlymussel, Cracking Hemistena lata E Virginia Bivalve

Pearlymussel,

Cumberland Bean Villosa trabalis E Virginia Bivalve

Pearlymussel,

Cumberland Monkeyface Quadrula intermedia E Virginia Bivalve

Pearlymussel, Dromedary Dromus dromas E Virginia Bivalve

### 305 INVNAME SCINAME Status STATE

NAME Taxon

Pearlymussel, Green

blossom Epioblasma torulosa gubernaculum E Virginia Bivalve

Pearlymussel, Little

wing Pegias fabula E Virginia Bivalve

Purple Bean Villosa perpurpurea E Virginia Bivalve

Rabbitsfoot, Rough Quadrula cylindrica strigillata E Virginia Bivalve

Rayed Bean Villosa fabalis E Virginia Bivalve

Riffleshell, Tan Epioblasma florentina walkeri (=E. walkeri) E Virginia Bivalve

Sheepnose mussel Plethobasus cyphyus E Virginia Bivalve

Spectaclecase mussel Cumberlandia monodonta E Virginia Bivalve

Spinymussel, James

River Pleurobema collina E Virginia Bivalve

Isopod, Lee County

Cave Lirceus usdagalun E Virginia Crustacean

Isopod, Madison Cave Antrolana lira T Virginia Crustacean

Bittercress, Small

anthered Cardamine micranthera E Virginia Dicot

Chaffseed, American Schwalbea americana E Virginia Dicot

Coneflower, Smooth Echinacea laevigata E Virginia Dicot

Harperella Ptilimnium nodosum E Virginia Dicot

Mallow, Peter's

Mountain Iliamna corei E Virginia Dicot

Rock

- cress, Shale

Barren Arabis serotina E Virginia Dicot

Sumac, Michaux's Rhus michauxii E Virginia Dicot

Sunflower,

Schweinitz's Helianthus schweinitzii E Virginia Dicot

Amaranth, Seabeach Amaranthus pumilus T Virginia Dicot

Birch, Virginia Round

leaf Betula uber T Virginia Dicot

Joint

- vetch, Sensitive Aeschynomene virginica T Virginia Dicot

### 306 INVNAME SCINAME Status STATE

NAME Taxon

Sneezeweed, Virginia Helenium virginicum T Virginia Dicot

Spiraea, Virginia Spiraea virginiana T Virginia Dicot

Darter, Duskytail Etheostoma percnurum E Virginia Fish

Logperch, Conasauga Percina jenkinsi E Virginia Fish

Logperch, Roanoke Percina rex E Virginia Fish

Sturgeon, Shortnose Acipenser brevirostrum E Virginia Fish

Chub, Slender Erimystax cahni T Virginia Fish

Chub, Spotfin Erimonax monachus T Virginia Fish

Dace, Blackside Phoxinus cumberlandensis T Virginia Fish

Madtom, Yellowfin Noturus flavipinnis T Virginia Fish

Snail, Virginia Fringed

Mountain Polygyriscus virginianus E Virginia Gastropod

Butterfly, Mitchell's Satyr Neonympha mitchellii

mitchellii E Virginia Insect

Beetle, Northeastern Beach Tiger Cicindela dorsalis dorsalis T Virginia Insect

Bat, Gray Myotis grisescens E Virginia Mammal

Bat, Indiana Myotis sodalis E Virginia Mammal

Bat, Ozark Big

- eared Corynorhinus (=Plecotus) townsendii ingens E Virginia Mammal

Squirrel, Carolina Northern Flying Glaucomys sabrinus

coloratus E Virginia Mammal

Squirrel, Delmarva

Peninsula Fox Sciurus niger cinereus E Virginia Mammal

Squirrel, Virginia Northern Flying Glaucomys sabrinus fuscus E Virginia Mammal

Whale, Blue Balaenoptera musculus E Virginia Mammal

Bulrush, Northeastern (=Barbed Bristle) Scirpus ancistrochaetus E Virginia Monocot

Orchid, Eastern Prairie Fringed Platanthera leucophaea T Virginia Monocot

### 307 INVNAME SCINAME Status STATE

NAME Taxon

Pink, Swamp Helonias bullata T Virginia Monocot

Pogonia, Small

Whorled Isotria medeoloides T Virginia Monocot

Sea turtle, hawksbill Eretmochelys imbricata E Virginia Reptile

Sea turtle, Kemp's ridley Lepidochelys kempii E Virginia Reptile

Sea turtle, leatherback Dermochelys coriacea E Virginia Reptile

Sea turtle, green Chelonia mydas E/T Virginia Reptile

Sea turtle, loggerhead Caretta caretta E/T Virginia Reptile

Turtle, Bog Clemmys muhlenbergii T Virginia Reptile

Albatross, Short

- tailed Phoebastria (=Diomedea)

albatrus E Washington Bird

Murrelet, Marbled Brachyramphus marmoratus T Washington Bird

Owl, Northern Spotted Strix occidentalis caurina T Washington Bird

Plover, Western Snowy Charadrius alexandrinus

nivosus T Washington Bird

Checker

- mallow,

Wenatchee Mountains Sidalcea oregana var. calva E Washington Dicot

Lomatium, Bradshaw's Lomatium bradshawii E Washington Dicot

Sandwort, Marsh Arenaria paludicola E Washington Dicot

Stickseed, Showy Hackelia venusta E Washington Dicot

Catchfly, Spalding's Silene spaldingii T Washington Dicot

Checker

- mallow,

Nelson's Sidalcea nelsoniana T Washington Dicot

Howellia, Water Howellia aquatilis T Washington Dicot

### 308 INVNAME SCINAME Status STATE

NAME Taxon

Lupine, Kincaid's Lupinus sulphureus (=oreganus) ssp. kincaidii (=var. kincaidii) T Washington Dicot

Paintbrush, Golden Castilleja levisecta T Washington Dicot

Rockfish, Bocaccio Sebastes paucispinis E Washington Fish

Salmon, Sockeye Oncorhynchus (=Salmo)

nerka E Washington Fish

Salmon, Chinook Oncorhynchus (=Salmo) tshawytscha E/T Washington Fish

Steelhead Oncorhynchus (=Salmo) mykiss E/T Washington Fish

Trout, Apache Oncorhynchus apache T Washington Fish

Trout, Bull Salvelinus confluentus T Washington Fish

Butterfly, Oregon Silverspot Speyeria zerene hippolyta T Washington Insect

Caribou, Woodland Rangifer tarandus caribou E Washington Mammal

Deer, Columbian

White

- tailed Odocoileus virginianus

leucurus E Washington Mammal

Gray Wolf Canis lupus E Washington Mammal

Killer whale, Southern

Resident DPS Orcinus orca E Washington Mammal

Rabbit, Pygmy Brachylagus idahoensis E Washington Mammal

Whale, Blue Balaenoptera musculus E Washington Mammal

Whale, Gray Eschrichtius robustus E Washington Mammal

Bear, Grizzly Ursus arctos horribilis T Washington Mammal

Lynx, Canada Lynx canadensis T Washington Mammal

### 309 INVNAME SCINAME Status STATE

NAME Taxon

Ladies'

- tresses, Ute Spiranthes diluvialis T Washington Monocot

Sea turtle, leatherback Dermochelys coriacea E Washington Reptile

Sea turtle, green Chelonia mydas E/T Washington Reptile

Salamander, Cheat

Mountain Plethodon nettingi T West Virginia Amphibian

Fanshell Cyprogenia stegaria E West Virginia Bivalve

Mucket, Pink (Pearlymussel) Lampsilis abrupta E West Virginia Bivalve

Mussel, Clubshell Pleurobema clava E West Virginia Bivalve

Mussel, snuffbox Epioblasma triquetra E West Virginia Bivalve

Pearlymussel,

Tubercled

- blossom Epioblasma torulosa

torulosa E West Virginia Bivalve

Riffleshell, Northern Epioblasma torulosa rangiana E West Virginia Bivalve

Spinymussel, James

River Pleurobema collina E West Virginia Bivalve

Isopod, Madison Cave Antrolana lira T West Virginia Crustacean

Clover, Running

Buffalo Trifolium stoloniferum E West Virginia Dicot

Harperella Ptilimnium nodosum E West Virginia Dicot

Rock

- cress, Shale

Barren Arabis serotina E West Virginia Dicot

Spiraea, Virginia Spiraea virginiana T West Virginia Dicot

Snail, Flat

- spired

Three

- toothed Triodopsis platysayoides T West Virginia Gastropod

Bat, Indiana Myotis sodalis E West Virginia Mammal

Bat, Virginia Big

eared Corynorhinus (=Plecotus) townsendii virginianus E West Virginia Mammal

### 310 INVNAME SCINAME Status STATE

NAME Taxon

Puma (=Cougar),

Eastern Puma (=Felis) concolor (all subsp. except coryi) E West Virginia Mammal

Squirrel, Virginia Northern Flying Glaucomys sabrinus fuscus E West Virginia Mammal

Bulrush, Northeastern (=Barbed Bristle) Scirpus ancistrochaetus E West Virginia Monocot

Pogonia, Small

Whorled Isotria medeoloides T West Virginia Monocot

Warbler (=Wood),

Kirtland's Dendroica kirtlandii E Wisconsin Bird

Plover, Piping Charadrius melodus E/T Wisconsin Bird

Mussel, snuffbox Epioblasma triquetra E Wisconsin Bivalve

Mussel, Winged Mapleleaf Quadrula fragosa E Wisconsin Bivalve

Pearlymussel, Higgins' Eye Lampsilis higginsii E Wisconsin Bivalve

Sheepnose mussel Plethobasus cyphyus E Wisconsin Bivalve

Spectaclecase mussel Cumberlandia monodonta E Wisconsin Bivalve

Clover, Prairie Bush Lespedeza leptostachya T Wisconsin Dicot

Locoweed, Fassett's Oxytropis campestris var.

chartacea T Wisconsin Dicot

Milkweed, Mead's Asclepias meadii T Wisconsin Dicot

Monkshood, Northern

Wild Aconitum noveboracense T Wisconsin Dicot

Thistle, Pitcher's Cirsium pitcheri T Wisconsin Dicot

Butterfly, Karner Blue Lycaeides melissa samuelis E Wisconsin Insect

Dragonfly, Hine's

Emerald Somatochlora hineana E Wisconsin Insect

Gray Wolf Canis lupus E Wisconsin Mammal

### 311 INVNAME SCINAME Status STATE

NAME Taxon

Lynx, Canada Lynx canadensis T Wisconsin Mammal

Iris, Dwarf Lake Iris lacustris T Wisconsin Monocot

Orchid, Eastern Prairie Fringed Platanthera leucophaea T Wisconsin Monocot

Toad, Wyoming Bufo baxteri (=hemiophrys) E Wyoming Amphibian

Crane, Whooping Grus americana E Wyoming Bird

Tern, Interior (population) Least Sterna antillarum E Wyoming Bird

Plover, Piping Charadrius melodus E/T Wyoming Bird

Penstemon, Blowout Penstemon haydenii E Wyoming Dicot

Butterfly Plant,

Colorado Gaura neomexicana var.

coloradensis T Wyoming Dicot

Yellowhead, Desert Yermo xanthocephalus T Wyoming Dicot

Chub, Bonytail Gila elegans E Wyoming Fish

Chub, Humpback Gila cypha E Wyoming Fish

Squawfish, Colorado Ptychocheilus lucius E Wyoming Fish

Sturgeon, Pallid Scaphirhynchus albus E Wyoming Fish

Sucker, Razorback Xyrauchen texanus E Wyoming Fish

Ferret, Black

- footed Mustela nigripes E Wyoming Mammal

Lynx, Canada Lynx canadensis T Wyoming Mammal

Mouse, Preble's Meadow Jumping Zapus hudsonius preblei T Wyoming Mammal

Ladies'

- tresses, Ute Spiranthes diluvialis T Wyoming Monocot

Orchid, Western Prairie Fringed Platanthera praeclara T Wyoming Monocot