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Exhibit 10.8
 SECOND AMENDMENT TO  SECURED TERM LOAN AGREEMENT
  RECITALS
   AGREEMENTS
 New Definition
 CFLS Project
 Permitted Investments Section 6.13(b)
  Exhibit B Exhibit B
(Revised) Form of Compliance Certificate Exhibit B Second Revised) Form of Compliance Certificate




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Miscellaneous




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BORROWER:BIOMED REALTY, L.P., a Maryland limited partnershipBy:
    
    BioMed Realty Trust, Inc., its sole general partnerBy:
    
    /s/ KENT GRIFFINName:
    
    Kent GriffinTitle:
    
    Chief Financial OfficerAddress:The undersigned, being the Guarantors under the
Agreement, hereby consent to this Amendment:BIOMED REALTY TRUST, INC.By:
    
    /s/ KENT GRIFFINName:
    
    Kent GriffinTitle:
    
    Chief Financial OfficerEACH SUBSIDIARY GUARANTOR LISTED ON ATTACHMENT 1By:
    
    BioMed Realty, L.P., a Maryland limited
partnership, the sole member of each such
Subsidiary GuarantorBy:
    
    BioMed Realty Trust, Inc., a Maryland corporation,
its sole general partnerBy:
    
    /s/ KENT GRIFFINName:
    
    Kent GriffinTitle:
    
    Chief Financial Officer




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ADMINISTRATIVE AGENT:KEYBANK NATIONAL ASSOCIATION, a national banking
association, as Administrative AgentBy:
    
    /s/ SCOTT CHILDSName:
    
    Scott ChildsTitle:
    
    Vice PresidentAddress:BANKS:KEYBANK NATIONAL ASSOCIATION, a national banking
associationBy:
    
    /s/ SCOTT CHILDSName:
    
    Scott ChildsTitle:
    
    Vice PresidentAddress:U.S. BANK NATIONAL ASSOCIATION, a national banking
associationBy:
    
    /s/ NICOLE K. WRIGHTName:
    
    Nicole K. WrightTitle:
    
    Vice PresidentAddress:SOCIETE GENERALEBy:
    
    /s/ C.H. BUTTERWORTHName:
    
    C.H. ButterworthTitle:
    
    DirectorAddress:COMPASS BANK, an Alabama banking corporationBy:
    
    /s/ JOHANNA DUKE PALEYName:
    
    Johanna Duke PaleyTitle:
    
    Senior Vice PresidentAddress:




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ALLIED IRISH BANKS, p.l.c.By:
    
    /s/ DOUGLAS S. MARRONName:
    
    Douglas S. MarronTitle:
    
    Senior Vice PresidentBy:
    
    /s/ THOMAS FRITTONName:
    
    Thomas FrittonTitle:
    
    Vice PresidentAddress:RAYMOND JAMES BANK, FSBBy:
    
    /s/ LAURENS F. SCHAAD JR.Name:
    
    Laurens F. Schaad Jr.Title:
    
    Vice PresidentAddress:GRAYSON & COBy:
    
    Boston Management and Research, as Investment
AdvisorBy:
    
    /s/ PAYSON F. SWAFFIELDTitle
    
    Payson F. SwaffieldTitle:
    
    Vice PresidentAddress:EATON VANCE VT FLOATING-RATE INCOME FUNDBy:
    
    Eaton Vance Management, as Investment AdvisorBy:
    
    /s/ PAYSON F. SWAFFIELDTitle
    
    Payson F. SwaffieldTitle:
    
    Vice PresidentAddress:




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EATON VANCE LIMITED DURATION INCOME FUNDBy:
    
    Eaton Vance Management, as Investment AdvisorBy:
    
    /s/ PAYSON F. SWAFFIELDTitle
    
    Payson F. SwaffieldTitle:
    
    Vice PresidentAddress:EATON VANCE SHORT DURATION DIVERSIFIED INCOME FUNDBy:
    
    Eaton Vance Management, as Investment AdvisorBy:
    
    /s/ PAYSON F. SWAFFIELDTitle
    
    Payson F. SwaffieldTitle:
    
    Vice PresidentAddress:EATON VANCE SENIOR FLOATING-RATE TRUSTBy:
    
    Eaton Vance Management, as Investment AdvisorBy:
    
    /s/ PAYSON F. SWAFFIELDTitle
    
    Payson F. SwaffieldTitle:
    
    Vice PresidentAddress:EATON VANCE FLOATING-RATE INCOME TRUSTBy:
    
    Eaton Vance Management, as Investment AdvisorBy:
    
    /s/ PAYSON F. SWAFFIELDTitle
    
    Payson F. SwaffieldTitle:
    
    Vice PresidentAddress:




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EATON VANCE INSTITUTIONAL SENIOR LOAN FUNDBy:
    
    Eaton Vance Management, as Investment AdvisorBy:
    
    /s/ PAYSON F. SWAFFIELDTitle
    
    Payson F. SwaffieldTitle:
    
    Vice PresidentAddress:EATON VANCE SENIOR INCOME TRUSTBy:
    
    Eaton Vance Management, as Investment AdvisorBy:
    
    /s/ PAYSON F. SWAFFIELDTitle
    
    Payson F. SwaffieldTitle:
    
    Vice PresidentAddress:SENIOR DEBT PORTFOLIOBy:
    
    Boston Management and Research, as Investment
AdvisorBy:
    
    /s/ PAYSON F. SWAFFIELDTitle
    
    Payson F. SwaffieldTitle:
    
    Vice PresidentAddress:VAN KAMPEN SENIOR LOAN FUNDBy:
    
    Van Kampen Asset ManagementBy:
    
    /s/ CHRISTINA JAMIESONName:
    
    Christina JamiesonTitle:
    
    Executive DirectorAddress:




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VAN KAMPEN SENIOR INCOME TRUSTBy:
    
    Van Kampen Asset ManagementBy:
    
    /s/ CHRISTINA JAMIESONName:
    
    Christina JamiesonTitle:
    
    Executive DirectorAddress:MORGAN STANLEY PRIME INCOME TRUSTBy:
    
    /s/ JINNY K. KIMName:
    
    Jinny K. KimTitle:
    
    Executive DirectorAddress:PIONEER FLOATING RATE TRUSTBy:
    
    /s/ M. JASON BLACKBURNName:
    
    M. Jason BlackburnTitle:
    
    TreasurerAddress:HIGHLAND FLOATING RATE ADVANTAGE FUNDBy:
    
    /s/ M. JASON BLACKBURNName:
    
    M. Jason BlackburnTitle:
    
    TreasurerAddress:HIGHLAND LEGACY LIMITEDBy:
    
    Highland Capital Management, L.P., as Collateral
ManagerBy:
    
    Strand Advisors, Inc., Its General PartnerBy:
    
    /s/ BRIAN LOHRDINGName:
    
    Brian LohrdingTitle:
    
    TreasurerAddress:




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LOAN FUNDING IV LLCBy:
    
    Highland Capital Management, L.P., as Collateral
ManagerBy:
    
    Strand Advisors, Inc., Its General PartnerBy:
    
    /s/ BRIAN LOHRDINGName:
    
    Brian LohrdingTitle:
    
    TreasurerAddress:JASPER CLO, LTD.By:
    
    Highland Capital Management, L.P., as Collateral
ManagerBy:
    
    Strand Advisors, Inc., Its General PartnerBy:
    
    /s/ BRIAN LOHRDINGName:
    
    Brian LohrdingTitle:
    
    TreasurerAddress:LOAN FUNDING VII LLCBy:
    
    Highland Capital Management, L.P., as Collateral
ManagerBy:
    
    Strand Advisors, Inc., Its General PartnerBy:
    
    /s/ BRIAN LOHRDINGName:
    
    Brian LohrdingTitle:
    
    TreasurerAddress:EMERALD ORCHARD LIMITEDBy:
    
    /s/ WENDY CHEUNGName:
    
    Wendy CheungTitle:
    
    Authorized SignatoryAddress:




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GLENEAGLES CLO, LTD.By:
    
    Highland Capital Management, L.P., as Collateral
ManagerBy:
    
    Strand Advisors, Inc., Its General PartnerBy:
    
    /s/ BRIAN LOHRDINGName:
    
    Brian LohrdingTitle:
    
    TreasurerAddress:HFT REAL ESTATE CDO 2006  1, LTDBy:
    
    Highland Capital Management, L.P., as Collateral
ManagerBy:
    
    Strand Advisors, Inc., Its General PartnerBy:
    
    /s/ BRIAN LOHRDINGName:
    
    Brian LohrdingTitle:
    
    TreasurerAddress: