EX-4.3





 Exhibit 4.3 

Execution Version 

SYNEOS HEALTH, INC. 
 as
Issuer 
 EACH OF THE GUARANTORS PARTY HERETO 

as Guarantors 
 WELLS
FARGO BANK, NATIONAL ASSOCIATION 
  
  

as Trustee 
 First
Supplemental Indenture 
 Dated as of November 24, 2020 

to the Indenture dated as of 

November 24, 2020 
  

 
 3.625% Senior
Notes due 2029 












 TABLE OF CONTENTS 

 

							
	 	 	 	  	PAGE	 
	 ARTICLE 1. DEFINITIONS AND OTHER PROVISIONS OF GENERAL APPLICATION
	  	 	1	 
			
	 Section 1.01
	 	Scope of Supplemental Indenture	  	 	1	 
	 Section 1.02
	 	Definitions	  	 	2	 
		
	 ARTICLE 2. THE NOTES
	  	 	23	 
			
	 Section 2.01
	 	Title and Terms; Payments	  	 	23	 
	 Section 2.02
	 	Repurchase and Cancellation	  	 	24	 
		
	 ARTICLE 3. REDEMPTION AND PREPAYMENT
	  	 	25	 
			
	 Section 3.01
	 	Notice of Redemption	  	 	25	 
	 Section 3.02
	 	Effect of Notice of Redemption	  	 	25	 
	 Section 3.03
	 	Optional Redemption	  	 	25	 
	 Section 3.04
	 	[Reserved]	  	 	27	 
	 Section 3.05
	 	Mandatory Redemption	  	 	27	 
		
	 ARTICLE 4. COVENANTS
	  	 	27	 
			
	 Section 4.01
	 	Reports	  	 	27	 
	 Section 4.02
	 	[Reserved]	  	 	28	 
	 Section 4.03
	 	Liens	  	 	28	 
	 Section 4.04
	 	Offer to Repurchase Upon Change of Control Triggering Event	  	 	29	 
	 Section 4.05
	 	Exempted Transactions	  	 	30	 
	 Section 4.06
	 	Additional Guarantees	  	 	30	 
	 Section 4.07
	 	Sale and Leaseback Transactions	  	 	31	 
		
	 ARTICLE 5. SUCCESSORS
	  	 	31	 
			
	 Section 5.01
	 	Merger, Consolidation or Sale of Assets	  	 	31	 
	 Section 5.02
	 	Successor Corporation Substituted	  	 	32	 
	 Section 5.03
	 	Opinion of Counsel to Be Given to Trustee	  	 	33	 
		
	 ARTICLE 6. DEFAULT AND REMEDIES
	  	 	33	 
			
	 Section 6.01
	 	Events of Default	  	 	33	 
	 Section 6.02
	 	Acceleration	  	 	35	 
	 Section 6.03
	 	Other Remedies	  	 	35	 
	 Section 6.04
	 	Waiver of Past Defaults	  	 	35	 
	 Section 6.05
	 	Control by Majority	  	 	36	 
	 Section 6.06
	 	Limitation on Suits	  	 	36	 
	 Section 6.07
	 	Collection Suit by Trustee	  	 	36	 


  
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	 ARTICLE 7. LEGAL DEFEASANCE AND COVENANT DEFEASANCE
	  	 	36	 
			
	 Section 7.01
	 	Option to Effect Legal Defeasance or Covenant Defeasance	  	 	36	 
	 Section 7.02
	 	Legal Defeasance and Discharge	  	 	37	 
	 Section 7.03
	 	Covenant Defeasance	  	 	37	 
	 Section 7.04
	 	Conditions to Legal or Covenant Defeasance	  	 	38	 
	 Section 7.05
	 	Deposited Money and Government Securities to be Held in Trust; Other Miscellaneous Provisions	  	 	39	 
	 Section 7.06
	 	Repayment to Company	  	 	39	 
	 Section 7.07
	 	Reinstatement	  	 	40	 
		
	 ARTICLE 8. SATISFACTION AND DISCHARGE
	  	 	40	 
			
	 Section 8.01
	 	Satisfaction and Discharge of the Supplemental Indenture	  	 	40	 
	 Section 8.02
	 	Application of Trust Money	  	 	41	 
		
	 ARTICLE 9. GUARANTEES
	  	 	41	 
			
	 Section 9.01
	 	Guarantee	  	 	41	 
	 Section 9.02
	 	[Reserved]	  	 	42	 
	 Section 9.03
	 	Limitation on Guarantor Liability	  	 	42	 
	 Section 9.04
	 	Execution and Delivery	  	 	43	 
	 Section 9.05
	 	Guarantors May Consolidate, etc., on Certain Terms	  	 	43	 
	 Section 9.06
	 	Releases	  	 	44	 
		
	 ARTICLE 10. SUPPLEMENTAL INDENTURES
	  	 	45	 
			
	 Section 10.01
	 	Supplemental Indentures Without Consent of Holders	  	 	45	 
	 Section 10.02
	 	Supplemental Indentures With Consent of Holders	  	 	45	 
	 Section 10.03
	 	Notice of Amendment or Supplement	  	 	46	 
		
	 ARTICLE 11. MISCELLANEOUS
	  	 	47	 
			
	 Section 11.01
	 	Governing Law	  	 	47	 
	 Section 11.02
	 	No Security Interest Created	  	 	47	 
	 Section 11.03
	 	Trust Indenture Act	  	 	47	 
	 Section 11.04
	 	Benefits of Supplemental Indenture	  	 	47	 
	 Section 11.05
	 	Calculations	  	 	47	 
	 Section 11.06
	 	Effect of Headings and Table of Contents	  	 	47	 
	 Section 11.07
	 	Execution in Counterparts	  	 	47	 
	 Section 11.08
	 	Separability Clause	  	 	48	 
	 Section 11.09
	 	Ratification of Original Indenture	  	 	48	 
	 Section 11.10
	 	The Trustee	  	 	48	 
	 Section 11.11
	 	No Recourse Against Others	  	 	48	 


  
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 EXHIBIT 
  

							
	 Appendix A
	 	Provisions Relating to Initial Notes	  	 	I-1	 
			
	 Exhibit A
	 	Form of Note	  	 	A-1	 
			
	 Exhibit B
	 	Form of Supplemental Indenture	  	 	B-1	 


  
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 FIRST SUPPLEMENTAL INDENTURE (this “Supplemental Indenture”), dated
as of November 24, 2020, among Syneos Health, Inc., a Delaware corporation (the “Company”), the Guarantors listed on Schedule A hereto (the “Guarantors”) and Wells Fargo Bank, National Association
(the “Trustee”), as trustee under the Indenture, dated as of November 24, 2020, between the Company and the Trustee (as amended or supplemented from time to time in accordance with the terms thereof, the
“Original Indenture”). 
 RECITALS OF THE COMPANY 

WHEREAS, the Company executed and delivered the Original Indenture to the Trustee to provide, among other things, for the issuance, from time
to time, of the Company’s Securities, in an unlimited aggregate principal amount, in one or more series to be established by the Company under, and authenticated and delivered as provided in, the Original Indenture; 

WHEREAS, Section 9.1(j) of the Original Indenture provides for the Company and the Trustee to enter into supplemental indentures to the
Original Indenture to establish the form and terms of Securities of any series as contemplated by Sections 2.1 and 2.2 of the Original Indenture; 

WHEREAS, the Board of Directors of the Company has duly adopted resolutions authorizing the Company to execute and deliver this Supplemental
Indenture; 
 WHEREAS, pursuant to the terms of the Original Indenture, the Company desires to establish a new series of its Securities to
be known as its “3.625% Senior Notes due 2029” (the “Notes”), the form and substance of such Notes and the terms, provisions and conditions thereof to be set forth as provided in the Original Indenture and this
Supplemental Indenture; 
 WHEREAS, the Form of Note, the certificate of authentication to be borne by each Note and the Form of Assignment
and Transfer contemplated under the terms of the Notes are to be substantially in the forms hereinafter provided; and 
 WHEREAS, the
Company and the Guarantors have requested that the Trustee execute and deliver this Supplemental Indenture. 
 NOW, THEREFORE, THIS
SUPPLEMENTAL INDENTURE WITNESSETH, for and in consideration of the premises and the purchases of the Notes by the Holders thereof, it is mutually agreed, for the benefit of the Company and the Guarantors and the equal and proportionate benefit of
all Holders of the Notes, as follows: 
 ARTICLE 1. 

DEFINITIONS AND OTHER PROVISIONS OF GENERAL APPLICATION 

Section 1.01 Scope of Supplemental Indenture. Unless otherwise stated, the terms and provisions contained in the Original Indenture shall
constitute, and are hereby expressly made, a part of this Supplemental Indenture and the Company, the Guarantors and the Trustee, by their execution and delivery of this Supplemental Indenture, expressly agree to such terms and provisions and to be
bound thereby. Notwithstanding any of the foregoing to the contrary, the provisions of this Supplemental Indenture shall supersede any corresponding provisions in the Original Indenture, and to the extent any provision of the Original Indenture
conflicts with the express provisions of this Supplemental Indenture, the provisions of this Supplemental Indenture shall govern and be controlling. The changes, modifications and supplements to the Original Indenture effected by this Supplemental
Indenture shall be applicable only with respect to, and shall only govern the terms of, the Notes, which may be issued from time to time, and shall not apply to any other Securities that may be issued under the Original Indenture unless a
supplemental indenture with respect to such other Securities specifically incorporates such changes, modifications and supplements. 

  
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 Section 1.02 Definitions. 

For all purposes of this Supplemental Indenture, except as otherwise expressly provided or unless the context otherwise requires: 

(a) the terms defined in this Article 1 shall have the meanings assigned to them in this Article 1 and include the plural as well as
the singular; 
 (b) all words, terms and phrases defined in the Original Indenture (but not otherwise defined herein) shall have the same
meanings as in the Original Indenture; 
 (c) all accounting terms not otherwise defined herein shall have the meanings assigned to them in
accordance with GAAP, and, except as otherwise herein expressly provided, the term “GAAP” with respect to any computation required or permitted hereunder shall mean such accounting principles as are generally accepted at the date of this
instrument; and 
 (d) the words “herein,” “hereof” and “hereunder” and other words of similar import refer to
this Supplemental Indenture as a whole and not to any particular Article, Section or other subdivision. 
 “Additional
Notes” has the meaning specified in Section 2.01. 
 “Advent” means Advent International
Corporation and its Affiliates. 
 “Affiliate” of any specified Person means any other Person directly or indirectly
controlling or controlled by or under direct or indirect common control with such specified Person. For purposes of this definition, “control,” as used with respect to any Person, means the possession, directly or indirectly, of the power
to direct or cause the direction of the management or policies of such Person, whether through the ownership of voting securities, by agreement or otherwise. For purposes of this definition, the terms “controlling,” “controlled
by” and “under common control with” have correlative meanings. 
 “Appendix” has the meaning set
forth in Section 2.01. 
 “Applicable Premium” means, with respect to any Note being redeemed pursuant to
Section 3.03(b) on any redemption date, the greater of: 
 (1) 1.0% of the principal amount of the Note; or 

(2) the excess, if any, of: 
 (a)
the present value at such redemption date of (i) the redemption price of the Note at January 15, 2024 (such redemption price being set forth in the table appearing in Section 3.03(d)) plus (ii) all required interest payments due
on the Note through January 15, 2024 (excluding accrued but unpaid interest to the redemption date), computed using a discount rate equal to the Treasury Rate as of such redemption date plus 50 basis points; over 

(b) the principal amount of the Note. 

  
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 “Attributable Indebtedness” means, with respect to any Sale and
Lease Back Transaction, at the time of determination, the lesser of (1) the sale price of the property so leased multiplied by a fraction the numerator of which is the remaining portion of the base term of the lease included in such transaction
and the denominator of which is the base term of such lease, and (2) the total obligation (discounted to the present value at the implicit interest factor, determined in accordance with GAAP, included in the rental payments) of the lessee for
rental payments (other than amounts required to be paid on account of property taxes as well as maintenance, repairs, insurance, water rates and other items which do not constitute payments for property rights) during the remaining portion of the
base term of the lease included in such transaction. 
 “Beneficial Owner” has the meaning assigned to such term in
Rule 13d-3 and Rule 13d-5 under the Exchange Act, except that in calculating the beneficial ownership of any particular “person” (as that term is used in
Section 13(d)(3) of the Exchange Act), such “person” will be deemed to have beneficial ownership of all securities that such “person” has the right to acquire by conversion or exercise of other securities, whether such right
is currently exercisable or is exercisable only after the passage of time. The terms “Beneficially Owns” and “Beneficially Owned” have a corresponding meaning. 

“Board of Directors” means: 

(1) with respect to a corporation, the board of directors of the corporation or any committee thereof duly authorized to act on behalf of such
board; 
 (2) with respect to a partnership, the board of directors of the general partner of the partnership; 

(3) with respect to a limited liability company, the managing member or members or any controlling committee of managing members thereof; and

 (4) with respect to any other Person, the board or committee of such Person serving a similar function. 

“Calculation Date” has the meaning specified in the definition of “Consolidated Net Secured Leverage Ratio.”

 “Capital Lease Obligation” of any Person means the obligations of such Person to pay rent or other amounts under
any lease of (or other arrangement conveying the right to use) real or personal property, or a combination thereof, which obligations are required to be classified and accounted for as capital leases on a balance sheet of such Person under GAAP, and
the amount of such obligations shall be the capitalized amount thereof determined in accordance with GAAP. 
 “Capital
Stock” means: 
 (1) in the case of a corporation, corporate stock; 

(2) in the case of an association or business entity, any and all shares, interests, participations, rights or other equivalents (however
designated) of corporate stock; 
 (3) in the case of a partnership or limited liability company, partnership interests (whether general or
limited) or membership interests; and 

  
 3 













 (4) any other interest or participation that confers on a Person the right to receive a
share of the profits and losses of, or distributions of assets of, the issuing Person, 
 but excluding from all of the foregoing any debt securities
exchangeable or convertible into Capital Stock, whether or not such debt securities include any right of participation with Capital Stock. 

“Cash Equivalents” means: 

(1) Money, cash or currency, in each case determined in accordance with GAAP; 

(2) in the case of any Foreign Subsidiary that is a Subsidiary, (a) such local currencies held by it from time to time in the ordinary
course of business and (b) the currency of any country that is a member of the Organization for Economic Cooperation and Development; 

(3) securities issued or directly and fully guaranteed or insured by the United States government or any agency or instrumentality of the
United States government (provided that the full faith and credit of the United States is pledged in support of those securities) having maturities of not more than 24 months from the date of acquisition; 

(4) certificates of deposit and eurodollar time deposits with maturities of one year or less from the date of acquisition, bankers’
acceptances with maturities not exceeding one year and overnight bank deposits, in each case, with any lender party to a Credit Facility or with any commercial bank having capital and surplus in excess of $500.0 million; 

(5) repurchase obligations with a term of not more than seven days for underlying securities of the types described in clauses (3) and
(4) above entered into with any financial institution meeting the qualifications specified in clause (4) above; 
 (6) commercial paper
having one of the two highest ratings obtainable from Moody’s or S&P and, in each case, maturing within 12 months after the date of acquisition; 

(7) marketable short-term money market and similar securities having a rating of at least P-2 or A-2 from either Moody’s or S&P, respectively (or, if at any time neither Moody’s nor S&P shall be rating such obligations, an equivalent rating from another “nationally recognized statistical
rating organization” within the meaning of Rule 3(a)(62) under the Exchange Act selected by the Company as a replacement agency) and in each case maturing within 24 months after the date of creation or acquisition thereof; 

(8) readily marketable direct obligations issued by any state, commonwealth or territory of the United States or any political subdivision or
taxing authority thereof having an Investment Grade rating from either Moody’s or S&P with maturities of 12 months or less from the date of acquisition; and 

(9) money market funds at least 95% of the assets of which constitute Cash Equivalents of the kinds described in clauses (1) through (8) of this
definition. 
 “Change of Control” means the occurrence of any of the following: 

(1) the direct or indirect sale, lease, transfer, conveyance or other disposition (other than by way of merger or consolidation), in one or a
series of related transactions, of all or substantially all of the properties or assets of the Company and its Subsidiaries taken as a whole to any Person (including any “person” (as that term is used in Section 13(d)(3) of the
Exchange Act)) other than the Company or one of its Subsidiaries; or 

  
 4 













 (2) the consummation of any transaction (including, without limitation, any merger or
consolidation), the result of which is that any Person or “group” (as such term is used in Section 13(d)(3) of the Exchange Act) becomes the Beneficial Owner, directly or indirectly, of more than 50% of the Voting Stock of the
Company, measured by voting power rather than number of shares, other than any Sponsor; or 
 (3) the Company consolidates with, or merges
with or into, any Person, or any Person consolidates with, or merges with or into, the Company, in any such event pursuant to a transaction in which any of the outstanding Voting Stock of the Company is converted into or exchanged for cash,
securities or other property, other than any such transaction where: 
 (a) the Voting Stock of the Company outstanding immediately prior to
such transaction is converted into or exchanged for the Voting Stock of such surviving or transferee Person (or any direct or indirect parent thereof) immediately after giving effect to such transaction; and 

(b) the holders of the Voting Stock of the Company immediately prior to such transaction own, directly or indirectly, not less than a majority
of the Voting Stock of the Company or such surviving or transferee Person (or any direct or indirect parent thereof) immediately after giving effect to such transaction. 

Notwithstanding the foregoing, a transaction will not be deemed to involve a Change of Control solely as a result of the Company becoming a
direct or indirect Wholly-Owned Subsidiary of another company (whether the Company is directly owned by such company or indirectly through other subsidiaries of such company); provided that no “Person” or “group” (as such
terms are defined above) is the Beneficial Owner, directly or indirectly, of more than a majority of the total voting power of the Voting Stock of such company. 

“Charge” means any charge, expense, cost, accrual, reserve or loss of any kind. 

“Company” has the meaning specified in the first paragraph of this Supplemental Indenture. 

“Consolidated EBITDA” means, with respect to any Person on a consolidated basis for any period, the sum of: 

(1) Consolidated Net Income for such period; plus 

(2) to the extent not otherwise included in the determination of Consolidated Net Income for such period, the amount of any proceeds of any
business interruption insurance policy in an amount representing the earnings for the applicable period that such proceeds are intended to replace (whether or not then received so long as such Person in good faith expects to receive such proceeds
within the next four Fiscal Quarters (it being understood that to the extent such proceeds are not actually received within such Fiscal Quarters, such proceeds shall be deducted in calculating Consolidated EBITDA for such Fiscal Quarters));
plus 
 (3) without duplication, those amounts which, in the determination of Consolidated Net Income for such period, have been
deducted for: 
 (a) Consolidated Interest Expense; 

  
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 (b) Charges with respect to any de novo facility, including any construction, pre-opening and start-up period prior to opening, until such facility has been open and operating for a period of 18 consecutive months; 

(c) Taxes paid and any provision for Taxes, including income, capital, federal, state, local, franchise and similar Taxes, property Taxes,
foreign withholding Taxes and foreign unreimbursed value added Taxes (including penalties and interest related to any such Tax or arising from any Tax examination, and including pursuant to any Tax sharing arrangement or as a result of any Tax
distribution) of such Person paid or accrued during the relevant period; 
 (d) (A) depreciation, (B) amortization (including
amortization of goodwill, software and other intangible assets), (C) any impairment Charge (including any bad debt expense) and (D) any asset write-off and/or write-down; 

(e) any non-cash Charge, including the excess of GAAP rent expense over actual cash rent paid during
such period due to the use of straight line rent for GAAP purposes (provided that to the extent that any such non-cash Charge represents an accrual or reserve for any potential cash item in any future
period, (A) such Person may elect not to add back such non-cash Charge in the current period and (B) to the extent such Person elects to add back such non-cash
Charge, the cash payment in respect thereof in such future period shall be subtracted from Consolidated EBITDA (as a deduction in calculating net income or otherwise) to such extent); 

(f) any non-cash compensation Charge and/or any other non-cash
Charge arising from the granting of any stock option or similar arrangement (including any profits interest), the granting of any stock appreciation right and/or similar arrangement (including any repricing, amendment, modification, substitution or
change of any such stock option, stock appreciation right, profits interest or similar arrangement); 
 (g) (A) any Charge incurred
(1) in connection with any transaction (in each case, regardless of whether consummated), and whether or not permitted under the Indenture, including any issuance and/or incurrence of Indebtedness and/or any issuance and/or offering of Capital
Stock (including, in each case, by any parent entity), any Investment, any acquisition, any disposition, any recapitalization, any merger, consolidation or amalgamation, any option buyout or any repayment, redemption, refinancing, amendment or
modification of Indebtedness (including any amortization or write-off of debt issuance or deferred financing costs, premiums and prepayment penalties) or any similar transaction, and/or (2) in connection
with any public offering (whether or not consummated), (C) the amount of any Charge that is actually reimbursed or reimbursable by one or more third parties pursuant to indemnification or reimbursement provisions or similar agreements or insurance;
provided that in respect of any Charge that is added back in reliance on clause (C) above, the relevant Person in good faith expects to receive reimbursement for such fee, cost, expense or reserve within the next four Fiscal Quarters (it
being understood that to the extent any reimbursement amount is not actually received within such Fiscal Quarters, such reimbursement amount shall be deducted in calculating Consolidated EBITDA for such Fiscal Quarters) and/or (D) Public
Company Costs; 
 (h) the amount of any Charge or deduction associated with any Subsidiary that is attributable to any non-controlling interest and/or minority interest of any third party; 

  
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 (i) without duplication of any amount referred to in clause (2) above, the amount of
(A) any Charge to the extent that a corresponding amount is received in cash by such Person from a Person other than such Person, the Company or any Subsidiary of such Person under any agreement providing for reimbursement of such expense or
(B) any Charge with respect to any liability or casualty event, business interruption or any product recall, (i) so long as such Person has submitted in good faith, and reasonably expects to receive payment in connection with, a claim for
reimbursement of such amounts under its relevant insurance policy (with a deduction in the applicable future period for any amount so added back to the extent not so reimbursed within the next four Fiscal Quarters) or (ii) without duplication
of amounts included in a prior period under clause (B)(i) above, to the extent such Charge is covered by insurance proceeds received in cash during such period (it being understood that if the amount received in cash under any such agreement in any
period exceeds the amount of expense paid during such period, any excess amount received may be carried forward and applied against any expense in any future period); 

(j) the amount of management, monitoring, consulting, transaction and advisory fees and related indemnities and expenses (including
reimbursements) pursuant to any sponsor management agreement and payments made to any Investor (and/or its Affiliates or management companies) for any financial advisory, financing, underwriting or placement services or in respect of other
investment banking activities and payments to outside directors of the Company or a parent entity actually paid by or on behalf of, or accrued by, such Person or any of its subsidiaries; provided that such payment is permitted under the
Indenture; 
 (k) any Charge attributable to the undertaking and/or implementation of new initiatives, business optimization activities,
cost savings initiatives, cost rationalization programs, operating expense reductions and/or synergies and/or similar initiatives and/or programs (including in connection with any integration, restructuring or transition, any reconstruction,
decommissioning, recommissioning or reconfiguration of fixed assets for alternative uses, any facility opening and/or pre-opening), including the following: any inventory optimization program and/or any
curtailment, any business optimization Charge, any restructuring Charge (including any Charge relating to any tax restructuring), any Charge relating to the closure or consolidation of any facility (including but not limited to rent termination
costs, moving costs and legal costs), any systems implementation Charge, any severance Charge, any Charge relating to entry into a new market, any Charge relating to any strategic initiative, any signing Charge, any retention or completion bonus,
any expansion and/or relocation Charge, any Charge associated with any modification to any pension and postretirement employee benefit plan, any software development Charge, any Charge associated with new systems design, any implementation Charge,
any project startup Charge, any Charge in connection with new operations, any Charge in connection with unused warehouse space, any Charge relating to a new contract, any consulting Charge and/or any corporate development Charge; plus 

(l) the amount of any Charge incurred or accrued in connection with any single or one-time event,
including in connection with (A) any acquisition consummated after the date of the Indenture (including legal, accounting and other professional fees and expenses incurred in connection with acquisitions and other similar Investments made prior
to the date of the Indenture), (B) the closing, consolidation or reconfiguration of any facility during such period or (C) one-time consulting costs; plus 

(4) to the extent not included in Consolidated Net Income for such period, cash actually received (or any netting arrangement resulting in
reduced cash expenditures) during such period so long as the non-cash gain relating to the relevant cash receipt or netting arrangement was deducted in the calculation of Consolidated EBITDA (including any
component definition) pursuant to clause (h) below for any previous period and not added back; plus 

  
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 (5) the full pro forma “run rate” cost savings, operating expense reductions,
operational improvements and synergies (collectively, “Expected Cost Savings”) (net of actual amounts realized) that are reasonably identifiable and factually supportable (in the good faith determination of such Person) related to any
permitted acquisition, Investment, Disposition, operating improvement, restructuring, cost savings initiative, any similar initiative (including the renegotiation of contracts and other arrangements) and/or specified transaction (any such operating
improvement, restructuring, cost savings initiative or similar initiative or specified transaction, a “Business Optimization Initiative”); provided that such Expected Cost Savings are expected by the Company in good faith to result from
actions that have been taken or with respect to which substantial steps have been taken or are expected to be taken (in the good faith determination of the Company) prior to the date of the Indenture or within 24 months of the consummation of such
transaction or the taking of such initiative; provided, further, that the aggregate amounts added back pursuant to this clause (e) in any period shall not exceed 35% of Consolidated EBITDA for such period; it being understood and
agreed that the 35% cap described in this further proviso shall not apply to amounts that would be permitted to be included in pro forma financial statements prepared in accordance with Regulation S-X under
the Securities Act; plus 
 (6) adjustments of the nature used in connection with the calculation of “Adjusted EBITDA” as
set forth in footnote (6) of “Summary—Summary condensed consolidated financial and operating data” contained in the Offering Memorandum applied in good faith to the extent such adjustments continue to be applicable during the
period in which Consolidated EBITDA is being calculated; plus 
 (7) the amount of any revenue that is attributable to services
performed during such period but is not included in Consolidated Net Income for such period; it being understood that if such revenue is added back in calculating Consolidated EBITDA for such period, such revenue shall not be included in
Consolidated Net Income in the period in which it is actually recognized; plus 
 (8) the amount of any loss or discount on any sale
of any receivable and/or any related asset in connection with any Permitted Receivables Facility; minus 
 (9) any amount which, in
the determination of Consolidated Net Income for such period, has been included for any non-cash income or non-cash gain, all as determined in accordance with GAAP
(provided that if any non-cash income or non-cash gain represents an accrual or deferred income in respect of potential cash items in any future period, such
Person may determine not to deduct the relevant non-cash gain or income in the then-current period); minus 

(10) the amount of any cash payment made during such period in respect of any non-cash accrual,
reserve or other non-cash Charge that is accounted for in a prior period which was added to Consolidated Net Income to determine Consolidated EBITDA for such prior period and which does not otherwise reduce
Consolidated Net Income for the current period. 
 “Consolidated Interest Expense” means, with respect to any Person
for any period, the sum of (a) consolidated total interest expense of such Person and its Subsidiaries for such period, whether paid or accrued and whether or not capitalized (including (without duplication), amortization of any debt issuance
cost and/or original issue discount, any premium paid to obtain payment, financial assurance or similar bonds, any interest capitalized during construction, any non-cash interest payment, the interest
component of any deferred payment obligation, the interest component of any payment under any Capital Lease Obligation (regardless of whether accounted for as interest expense under GAAP), any commission, 

  
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 discount and/or other fee or charge owed with respect to any letter of credit and/or bankers’
acceptance, any fee and/or expense paid to the administrative agent under the Credit Agreement in connection with its services thereunder, any other bank, administrative agency (or trustee) and/or financing fee and any cost associated with any
surety bond in connection with financing activities (whether amortized or immediately expensed)) plus (b) any cash dividend paid or payable in respect of Capital Stock during such period other than to such Person or any of the Company or the
Guarantors, plus (c) any net losses or obligations arising from any Hedging Obligation and/or other derivative financial instrument issued by such Person for the benefit of such Person or its subsidiaries, in each case determined on a
consolidated basis for such period. For purposes of this definition, interest in respect of any capital lease shall be deemed to accrue at an interest rate reasonably determined by such Person to be the rate of interest implicit in such capital
lease in accordance with GAAP. 
 “Consolidated Net Income” means, with respect to any Person (the “Subject
Person”) on a consolidated basis for any period, an amount equal to the net income (loss) of such Subject Person and its Subsidiaries, determined in accordance with GAAP, but excluding: 

(1) (i) the income of any Person (other than a Subsidiary of the Subject Person) in which any other Person (other than the Subject Person or
any of its Subsidiaries) has a joint interest, except to the extent of the amount of dividends or distributions or other payments (including any ordinary course dividend, distribution or other payment) paid in cash (or to the extent converted into
cash) to the Subject Person or any of its Subsidiaries by such Person during such period, (ii) the loss of any Person (other than a Subsidiary of the Subject Person) in which any other Person (other than the Subject Person or any of its
Subsidiaries) has a joint interest, other than to the extent that the Subject Person or any of its Subsidiaries has contributed cash or Cash Equivalents to such Person in respect of such loss during such period; 

(2) any gain or loss (less all fees and expenses chargeable thereto) attributable to any asset disposition (including asset retirement costs)
or of returned or surplus assets outside the ordinary course of business; 
 (3) (i) any gain or Charge from (A) any extraordinary item
(as determined in good faith by such Person) and/or (B) any non-recurring or unusual item (as determined in good faith by such Person) and/or (ii) any Charge associated with and/or payment of any
actual or prospective legal settlement, fine, judgment or order; 
 (4) any net gain or Charge with respect to (i) any disposed,
abandoned, divested and/or discontinued asset, property or operation (other than, at the option of the Company, any asset, property or operation pending the disposal, abandonment, divestiture and/or termination thereof), (ii) any disposal,
abandonment, divestiture and/or discontinuation of any asset, property or operation (other than, at the option of such Person, relating to assets or properties held for sale or pending the divestiture or termination thereof) and/or (iii) any
facility that has been closed during such period; 
 (5) any net income or Charge (less all fees and expenses or charges related thereto)
attributable to the early extinguishment of Indebtedness (and the termination of any associated Hedging Obligation); 
 (6) (i) any Charge
incurred as a result of, in connection with or pursuant to any management equity plan, profits interest or stock option plan or any similar equity plan or agreement (including any deferred compensation arrangement) and (ii) any Charge incurred
in connection with the rollover, acceleration or payout of Capital Stock held by management of the Company and/or any Subsidiary, in each case under this clause (ii), to the extent that any cash Charge is funded with net cash proceeds contributed
(other than by the Company or any Guarantor) to the relevant Person as a capital contribution or as a result of the sale or issuance of Capital Stock; 

  
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 (7) any Charge that is established, adjusted and/or incurred, as applicable, within 12
months after the closing of any other acquisition that is required to be established, adjusted or incurred, as applicable, as a result of such acquisition in accordance with GAAP, (A) the effects of adjustments (including the effects of such
adjustments pushed down to the relevant Person and its subsidiaries) in component amounts required or permitted by GAAP (including, without limitation, in the inventory, property and equipment, lease, rights fee arrangements, software, goodwill,
intangible asset, in-process research and development, deferred revenue, advanced billing and debt line items thereof), resulting from the application of the acquisition method of accounting in relation to any
consummated acquisition or similar Investment or recapitalization accounting or the amortization or write-off of any amounts thereof, net of Taxes and/or (B) for any four consecutive Fiscal Quarters then
most recently ended for which financial statements of the Company have been delivered or are internally available including the Fiscal Quarter in which the relevant change was made, the cumulative effect of any change in accounting principles
(effected by way of either a cumulative effect adjustment or as a retroactive application, in each case, in accordance with GAAP) and/or any change resulting from the adoption or modification of accounting principles and/or policies in accordance
with GAAP (except that, if the Company determines in good faith that the cumulative effects thereof will not result in an impact of an aggregate amount in excess of $5,000,000 for the relevant period, the effects of any change, adoption or
modification of any such principle or policy may be included in any subsequent period after the Fiscal Quarter in which such change, adoption or modification was made); 

(8) any write-off or amortization made in such period of any deferred financing cost and/or premium
paid; 
 (9) (i) any realized or unrealized gain or loss in respect of (x) any obligation under any Hedging Obligation as determined in
accordance with GAAP and/or (y) any other derivative instrument pursuant to, in the case of this clause (y), Financial Accounting Standards Board’s Accounting Standards Codification No.
815-Derivatives and Hedging and (ii) any realized or unrealized foreign currency exchange gain or loss (including any currency re-measurement of Indebtedness, any
net gain or loss resulting from Hedging Obligations for currency exchange risk and any gain or loss resulting from intercompany Indebtedness, any foreign currency translation or transaction or any other currency-related risk); and 

(10) any deferred Tax expense associated with any tax deduction or net operating loss arising as a result of the Refinancing Transactions, or the release of
any valuation allowance related to any such item. 
 “Consolidated Net Secured Leverage Ratio” means, as of any date
of determination, the ratio of (1) the Indebtedness of the Company that is outstanding and measured according to GAAP and that is secured by a Lien (other than Exempted Liens and the aggregate principal amount of liens being incurred under
clause (1) of “Permitted Liens” on the same day) on the assets of the Company or any of its Subsidiaries as of such date minus Cash Equivalents included on the consolidated balance sheet of the Company as of the end of the most recent
fiscal quarter for which financial statements are available preceding the date of determination and still held by the Company as of such date to (2) the Consolidated EBITDA of the Company for the then most recently ended four full fiscal
quarters for which financial statements are available immediately preceding the date of determination, in each case with such pro forma adjustments as are consistent with the pro forma adjustment provisions set forth in this definition. 

  
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 In addition, for purposes of calculating the Consolidated Net Secured Leverage Ratio,
Investments, acquisitions, dispositions and mergers or consolidations that have been made by the specified Person or any of its Subsidiaries, or any Person or any of its Subsidiaries acquired by the specified Person or any of its Subsidiaries, and
including all related financing transactions and including increases in ownership of Subsidiaries, during the four-quarter reference period or subsequent to such reference period and on or prior to the date on which the event for which the
calculation of the Consolidated Net Secured Leverage Ratio is made (the “Calculation Date”), or that are to be made on the Calculation Date, will be given pro forma effect (as determined in good faith by a responsible financial or
accounting officer of the Company) as if they had occurred on the first day of the four-quarter reference period. 
 In the event that the
Company or any Subsidiary (x) creates or incurs any Liens to finance an acquisition or (y) assumes Liens of Persons that are acquired by the Company or any Subsidiary or merged into the Company or a Subsidiary in accordance with the terms
of this Indenture, the date of determination of the Consolidated Net Secured Leverage Ratio, as applicable, shall, at the option of the Company, be (a) the date that a definitive agreement for such acquisition is entered into and the
Consolidated Net Secured Leverage Ratio, shall be calculated giving pro forma effect to such acquisition and the other transactions to be entered into in connection therewith (including any incurrence or creation of Liens and the use of proceeds
thereof) consistent with the definition of the Consolidated Net Secured Leverage Ratio, and, for the avoidance of doubt, (A) if any such ratios are exceeded as a result of fluctuations in such ratio (including due to fluctuations in the
Consolidated EBITDA of the Company or the target company) at or prior to the consummation of the relevant acquisition, such ratios will not be deemed to have been exceeded as a result of such fluctuations solely for purposes of determining whether
such acquisition and any related transactions are permitted hereunder and (B) such ratios shall not be tested at the time of consummation of such acquisition or related transactions; provided, further, that if the Company elects
to have such determinations occur at the time of entry into such definitive agreement, (i) any such transaction shall be deemed to have occurred on the date the definitive agreement is entered into and to be outstanding thereafter for purposes
of calculating any ratios under this Indenture after the date of such agreement and before the earlier of the date of consummation of such acquisition or the date such agreement is terminated or expires without consummation of such acquisition and
(ii) to the extent any covenant baskets were utilized in satisfying any covenants, such baskets shall be deemed utilized until the earlier of the date of consummation of such acquisition or the date such agreement is terminated or expires
without consummation of such acquisition, but any calculation of Consolidated Net Income or Consolidated EBITDA for other purposes under the Indenture shall not reflect such acquisition until it has been consummated or (b) the date such
Indebtedness is incurred or assumed. 
 For purposes of this definition, whenever pro forma effect is to be given to an Investment,
acquisition, disposition and merger or consolidation, the pro forma calculations shall include factually supportable and identifiable pro forma cost savings related to operational efficiencies, expense reductions, strategic initiatives or
improvements or other synergies, in each case, projected by the Company in good faith to be realized based upon actions taken, committed to be taken or reasonably expected to be taken within 24 months of the Calculation Date (without duplication of
the amount of actual benefit realized during such period from such actions), which cost savings, improvements and synergies can be reasonably computed, as certified in writing by a responsible financial or accounting officer of the Company. Interest
on a Capital Lease Obligation shall be deemed to accrue at an interest rate reasonably determined by a responsible financial or accounting officer of the Company to be the rate of interest implicit in such Capital Lease Obligation in accordance with
GAAP. For purposes of making the computation referred to above, interest on any Indebtedness under revolving credit facilities computed on a pro forma basis shall be computed based upon the average daily balance of such Indebtedness during the
applicable period, or if lower, the maximum commitments under such revolving credit facilities as of the applicable Calculation Date. Interest on Indebtedness that may optionally be determined at an interest rate based upon a factor of a prime or
similar rate, a eurocurrency interbank offered rate, or other rate, shall be deemed to have been based upon the rate actually chosen, or, if none, then based upon such optional rate chosen as the Company may designate. 

  
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 “continuing” means, with respect to any Default or Event of Default,
that such Default or Event of Default has not been cured or waived. 
 “Corporate Trust Office” means the address of
the Trustee specified in Section 12.2 of the Original Indenture or such other address as to which the Trustee may give notice to the Company. 

“Covenant Defeasance” has the meaning specified in Section 7.03. 

“Credit Agreement” means that certain Credit Agreement, dated as of August 1, 2017, by and among the Company (as
Administrative Borrower), the other borrowers party thereto, the lenders from time to time party thereto, JPMorgan Chase Bank, N.A., as Administrative Agent, and the other parties from time to time party thereto (as amended by Amendment No. 1,
dated as of May 4, 2018, Amendment No. 2, dated as of March 26, 2019, and Amendment No. 3, dated as of April 7, 2020, and as further amended, restated, amended and restated, supplemented or otherwise modified from time to
time), including any related notes, Guarantees, collateral documents, instruments and agreements executed in connection therewith, and, in each case, as amended, restated, modified, renewed, refunded, replaced in any manner (whether upon or after
termination or otherwise) or refinanced (including by means of sales of debt securities to institutional investors) in whole or in part from time to time. 

“Credit Facilities” means, one or more debt facilities (including, without limitation, the Credit Agreement) or other
financing arrangements (including, without limitation, commercial paper facilities or indentures), in each case, providing for revolving credit loans, term loans, receivables financing (including through the sale of receivables to such lenders or to
special purpose entities formed to borrow from such lenders against such receivables), letters of credit or other indebtedness, including any notes, mortgages, guarantees, collateral documents, instruments and agreements executed in connection
therewith, in each case, as amended, supplemented, restated, modified, renewed, refunded, replaced in any manner (whether upon or after termination or otherwise) or refinanced (including by means of sales of debt securities) in whole or in part from
time to time, including any such replacement, refunding or refinancing facility or indenture that increases the amount permitted to be borrowed thereunder or alters the maturity thereof (provided that such increase in borrowings is permitted,
to the extent applicable, under Section 4.03) or adds Subsidiaries as additional borrowers or guarantors thereunder and whether by the same or any other agent, lender or group of lenders. 

“Custodian” means the Trustee, as custodian with respect to the Notes (so long as the Notes constitute Global Notes),
or any successor entity. 
 “Default” means any event that is, or with the passage of time or the giving of notice
or both would be, an Event of Default. 
 “Depository” means initially The Depository Trust Company until a
successor Depository shall have become such pursuant to the applicable provisions of the Indenture, and thereafter “Depository” shall mean such successor Depository. 

“Domestic Subsidiary” means any Subsidiary of the Company that is, at the time of determination, organized under the
laws of the United States or any state of the United States or the District of Columbia. 

  
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 “Equity Interests” means Capital Stock and all warrants, options or
other rights to acquire Capital Stock (but excluding any debt security that is convertible into, or exchangeable for, Capital Stock). 

“Equity Offering” means a public or private sale either: 

 

	 	(1)	 of Equity Interests of the Company by the Company (other than to a Subsidiary of the Company), or



  

	 	(2)	 of Equity Interests of a direct or indirect parent entity of the Company (other than to the Company or a
Subsidiary of the Company) to the extent that the net proceeds therefrom are contributed to the common equity capital of the Company. 



“Event of Default” has the meaning specified in Section 6.01. 

“Exchange Act” means the Securities Exchange Act of 1934, as amended, and the rules and regulations promulgated
thereunder. 
 “Fair Market Value” means the value that would be paid by a willing buyer to an unaffiliated willing
seller in a transaction not involving distress or necessity of either party, determined in good faith by the Board of Directors of the Company (unless otherwise provided in the Indenture). 

“Fall Away Date” has the meaning specified in Section 9.06. 

“FASB” means Financial Accounting Standards Board. 

“Fiscal Quarter” means a fiscal quarter of any Fiscal Year. 

“Fiscal Year” means the fiscal year of the Company ending December 31 of each calendar year. 

“Fixed Charges” means, with respect to any specified Person for any period, the sum, without duplication, of: 

(1) (a) the consolidated interest expense of such Person and its Subsidiaries for such period, to the extent such expense was deducted in
computing Consolidated Net Income, including, without limitation, (A) amortization of debt issuance costs and original issue discount, (B) non-cash interest payments (but excluding any non-cash interest expense attributable to the movement in the mark to market valuation of Hedging Obligations or other derivative instruments pursuant to GAAP), (C) the interest component of any deferred payment
obligations, (D) the interest component of all payments associated with Capital Lease Obligations, (E) commissions, discounts and other fees and charges incurred in respect of letter of credit or bankers’ acceptance financings, and
excluding, (v) penalties and interest relating to taxes, (w) any expense resulting from the discounting of Indebtedness in connection with the application of recapitalization or purchase accounting, (x) amortization of deferred
financing fees, debt issuance costs, commissions, fees and expenses, and original issue discount with respect to Indebtedness issued in connection with the Refinancing Transactions or any intercompany Indebtedness and (y) any expensing of
bridge, commitment and other financing fees in connection with any acquisitions after the date of this Supplemental Indenture, and net of the effect of all payments made or received pursuant to Hedging Obligations in respect of interest rates (but
excluding any one-time cash costs associated with breakage); plus 

  
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 (b) the consolidated interest expense of such Person and its Subsidiaries that was
capitalized during such period; plus 
 (c) any interest on Indebtedness of another Person that is guaranteed by such Person or one of
its Subsidiaries or secured by a Lien on assets of such Person or one of its Subsidiaries, whether or not such Guarantee or Lien is called upon; plus 

(d) all dividends, whether paid or accrued and whether or not in cash, on any series of preferred stock of such Person or any of its
Subsidiaries, other than dividends on Equity Interests payable solely in Equity Interests of the Company or to the Company or a Subsidiary of the Company; minus 

(2) (a) interest income of such Person and its Subsidiaries for such period; and 

(b) any amortization of deferred charges or debt discount resulting from the application of FASB Accounting Standards Codification Topic 470-20—Debt—Debt with Conversion and Other Options (formerly FASB Staff Position No. APB 14-1—Accounting for Convertible Debt Instruments That May Be Settled in
Cash Upon Conversion (Including Partial Cash Settlement)). 
 “Foreign Subsidiary” means, with respect to any
Person, any Subsidiary of such Person that is not organized or existing under the laws of the United States, any state thereof or the District of Columbia, and any Subsidiary of such Foreign Subsidiary. 

“Form of Assignment and Transfer” means the “Form of Assignment and Transfer” attached as Attachment 1 to
the Form of Note attached hereto as Exhibit A. 
 “GAAP” means generally accepted accounting principles set forth in
the opinions and pronouncements of the Accounting Principles Board of the American Institute of Certified Public Accountants and statements and pronouncements of the Financial Accounting Standards Board or in such other statements by such other
entity as have been approved by a significant segment of the accounting profession, which are in effect on the date of this Supplemental Indenture; provided that lease liabilities and associated expenses recorded by the Company pursuant to
ASU 2016-02, Leases, shall not be treated as Indebtedness and shall not be included in consolidated interest expense or Fixed Charges, unless the lease liabilities would have been treated as capital lease
obligations under GAAP as in effect prior to the adoption of ASU 2016-02, Leases (in which case such lease liabilities and associated expenses shall be treated as Capital Lease Obligations and included in
consolidated interest expense and Fixed Charges under the Indenture). 
 “Global Note” means any Note that is a
Global Security. 
 “Guarantee” of or by any Person means any obligation, contingent or otherwise, of the guarantor
guaranteeing or having the economic effect of guaranteeing any Indebtedness or other obligation of any other Person (the “primary obligor”) in any manner, whether directly or indirectly, and including any obligation of the
guarantor, direct or indirect: 
 (1) to purchase or pay (or advance or supply funds for the purchase or payment of) such Indebtedness or
other obligation or to purchase (or to advance or supply funds for the purchase of) any security for the payment thereof; 
 (2) to purchase
or lease property, securities or services for the purpose of assuring the owner of such Indebtedness or other obligation of the payment thereof; 

  
 14 













 (3) to maintain working capital, equity capital or any other financial statement condition
or liquidity of the primary obligor so as to enable the primary obligor to pay such Indebtedness or other obligation; or 
 (4) as an
account party in respect of any letter of credit or letter of guaranty issued to support such Indebtedness or obligation; 
 provided that the term
“Guarantee” will not include endorsements for collection or deposit in the ordinary course of business. In any computation of the Indebtedness or other liabilities of the obligor under any Guarantee, the Indebtedness or other obligations
that are the subject of such Guarantee will be assumed to be direct obligations of such obligor. 
 “Guarantee”
means the Guarantee by each Guarantor of the Company’s obligations under the Indenture and the Notes, in accordance with the provisions of the Indenture. 

“Guarantors” means any Subsidiary of the Company that issues a Guarantee by executing this Supplemental Indenture in
accordance with the provisions of the Indenture or executes a supplemental indenture in the form attached hereto as Exhibit B, and their respective successors and assigns, in each case, until the Guarantee of such Person has been released in
accordance with the provisions of the Indenture. 
 “Hedging Obligations” means, with respect to any specified
Person, the obligations of such Person under: 
 (1) interest rate swap agreements (whether from fixed to floating or from floating to
fixed), interest rate cap agreements and interest rate collar agreements; 
 (2) other agreements or arrangements designed to manage
interest rates or interest rate risk; and 
 (3) commodity swap agreement, commodity cap agreement, commodity collar agreement, foreign
exchange contract, currency swap agreement or any other agreements or arrangements designed to protect such Person against fluctuations in, or providing for the transfer or mitigation of risks related to, currency exchange rates or commodity prices,
in each case, either generally or under specific contingencies. 
 “Holder” means a person in whose name a Note is
registered. 
 “Immaterial Subsidiary” means, as of any date, any Subsidiary that is a Wholly-Owned Subsidiary whose
total assets do not exceed 7.5% of the consolidated assets of the Company and its Subsidiaries or whose revenues do not exceed 10.0% of the consolidated revenues of the Company and its Subsidiaries, determined as of the end of the Fiscal Quarter
most recently ended for which financial statements are available; provided that (1) a Subsidiary will not be considered to be an Immaterial Subsidiary if it, directly or indirectly, guarantees or otherwise provides direct credit support
for any other Indebtedness of the Company and (2) the aggregate amount of total assets of all Immaterial Subsidiaries shall not at any time exceed 7.5% of the consolidated assets of the Company and its Subsidiaries or whose revenues do not
exceed 10.0% of the consolidated revenues of the Company and its Subsidiaries, determined as of the end of the Fiscal Quarter most recently ended for which financial statements are available. 

  
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 “Indebtedness” means, with respect to any specified Person, any
indebtedness of such Person (excluding accrued interest (other than accrued interest or interest paid in kind that has accreted to the principal amount), accrued expenses and trade payables), whether or not contingent, in respect of borrowed money
and evidenced by bonds, notes, debentures or similar instruments or letters of credit (or, without duplication, reimbursement agreements in respect thereof). 

The amount of any Indebtedness outstanding as of any date will be: 

(1) the accreted value of the Indebtedness, in the case of any Indebtedness issued with original issue discount; 

(2) the principal amount of the Indebtedness, in the case of any other Indebtedness; and 

(3) in respect of Indebtedness of another Person secured by a Lien on the assets of the specified Person, the lesser of: 

(a) the Fair Market Value of such assets at the date of determination; and 

(b) the amount of the Indebtedness of the other Person. 

The term “Indebtedness” shall exclude any obligation under or in respect of any Permitted Receivables Facility. 

“Indenture” means the Original Indenture, as originally executed, and as supplemented by this Supplemental Indenture,
entered into pursuant to the applicable provisions of the Indenture, which, together, provide for the issuance of and establish the form and terms of the Notes, and as may be further supplemented from time to time by one or more supplements thereto.

 “Initial Notes” has the meaning specified in Section 2.01. 

“Interest Payment Date” means, with respect to the payment of interest on the Notes, each January 15 and
July 15 of each year. 
 “Investment Grade” means a rating equal to or higher than Baa3 (or the equivalent) by
Moody’s or BBB- (or the equivalent) by S&P, or, if either such entity ceases to rate the Notes for reasons outside of the control of the Company, the equivalent investment grade credit rating from any
other “nationally recognized statistical rating organization” within the meaning of Rule 3(a)(62) under the Exchange Act selected by the Company as a replacement agency. 

“Investments” means, with respect to any Person, all direct or indirect investments by such Person in other Persons
(including Affiliates) in the forms of loans (including Guarantees or other obligations), advances or capital contributions (excluding commission, travel and similar advances to officers and employees made in the ordinary course of business),
purchases or other acquisitions of Indebtedness, Equity Interests or other securities, together with all items that are or would be classified as investments on a balance sheet prepared in accordance with GAAP. Except as otherwise provided in the
Indenture, the amount of an Investment will be determined at the time the Investment is made and without giving effect to subsequent changes in value. 

“Investors” means (a) the Sponsors and (b) the Management Investors. 

  
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 “Issue Date” means, with respect to the Notes, November 24,
2020. 
 “Legal Defeasance” has the meaning specified in Section 7.02. 

“Lien” means, with respect to any asset, any mortgage, lien, pledge, charge, security interest or encumbrance of any
kind in respect of such asset, whether or not filed, recorded or otherwise perfected under applicable law, including any conditional sale or other title retention agreement, any lease in the nature thereof, any option or other agreement to sell or
give a security interest in and any filing of or agreement to give any financing statement under the Uniform Commercial Code (or equivalent statutes) of any jurisdiction; provided that in no event shall an operating lease be deemed to
constitute a Lien. 
 “Management Investors” means the officers, directors, managers, employees and members of
management of the Company, any parent entity and/or any subsidiary of the Company. 
 “Moody’s” means
Moody’s Investors Service, Inc., and any successor to its rating agency business. 
 “Net Proceeds” from a Sale
and Lease Back Transaction means cash payments received therefrom (including any cash payments received by way of deferred payment of principal pursuant to a note or installment receivable or otherwise and proceeds from the sale or other disposition
of any securities received as consideration, all purchase price adjustments, earn-outs and contingency payment obligations to which a seller may become entitled after the closing of such Sale and Lease Back Transaction and all holdbacks, in each
case, only as and when received in cash, but excluding any other consideration received in the form of assumption by the acquiring Person of Indebtedness or other obligations relating to such properties or assets or received in any other non-cash form), in each case net of (without duplication): (1) all legal, accounting, title and transfer or recording tax expenses, broker’s fees or commissions and other fees and expenses (including, without
duplication, any repatriation costs associated with receipt by the applicable taxpayer of such proceeds) incurred, and all federal, state, provincial, foreign and local taxes (whether on account of income, gains or otherwise) required to be accrued
as a liability under GAAP, as a consequence of such Sale and Lease Back Transaction; (2) all payments made on any Indebtedness which is secured by any assets subject to such Sale and Lease Back Transaction, in accordance with the terms of any
Lien upon or other security agreement of any kind with respect to such assets, or which must by its terms, or in order to obtain a necessary consent to such Sale and Lease Back Transaction, or by applicable law, be repaid out of the proceeds from
such Sale and Lease Back Transaction; (3) the deduction of appropriate amounts provided by the seller as a reserve, in accordance with GAAP, against any liabilities associated with the property or other assets disposed in such Sale and Lease
Back Transaction and retained by the Company or any Subsidiary after such Sale and Lease Back Transaction; (4) any portion of the purchase price from a Sale and Lease Back Transaction placed in escrow in connection with that Sale and Lease Back
Transaction; provided that upon the termination of that escrow, Net Proceeds will be increased by any portion of funds in the escrow that are released to the Company or any Subsidiary; and (5) the amount of any purchase price adjustment,
contingent or deferred payment obligation that the Company and/or any Subsidiary is obligated to pay to another Person in connection with a Sale and Lease Back Transaction. 

“Note” or “Notes” has the meaning specified in the fourth paragraph of the recitals of this
Supplemental Indenture, and shall include any Additional Notes issued pursuant to Section 2.01. 

“Obligations” means any principal, interest, penalties, fees, indemnifications, reimbursements, damages and other
liabilities payable under the documentation governing any Indebtedness, including interest accruing subsequent to the filing of a petition in a bankruptcy, reorganization or similar proceeding at the rate provided for in the documentation with
respect thereto, whether or not such interest is an allowed claim under applicable state, federal or foreign law. 

  
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 “Offering Memorandum” means the offering memorandum dated
November 18, 2020, pursuant to which the Initial Notes were offered to potential purchasers. 
 “Original
Indenture” has the meaning specified in the first paragraph of this Supplemental Indenture. 

“Outstanding” with respect to the Notes, has the meaning specified in Section 2.9 of the Original Indenture with
respect to Securities “outstanding,” as modified by Section 2.02. 
 “Paying Agent” has
the meaning set forth in the Original Indenture, which shall initially be the Trustee, and shall be the person authorized by the Company to pay the principal amount of, and premium and interest, if any, on, any Notes on behalf of the Company. 

“Permitted Liens” means: 

(1) Liens on assets of the Company or any of its Subsidiaries securing Indebtedness and other Obligations under Credit Facilities incurred
pursuant to this clause (1) not to exceed (a) $3.0 billion plus (b) the greater of (x) $750.0 million and (y) 100% of Consolidated EBITDA as of the last day of the most recently ended consecutive four Fiscal Quarters for which consolidated financial
statements are available; 
 (2) Liens in favor of the Company or the Guarantors; 

(3) Liens on property, shares of stock or other assets of a Person existing at the time such Person becomes a Subsidiary of the Company or is
merged with or into or consolidated with the Company or any Subsidiary of the Company; provided that such Liens were not created or incurred in contemplation of such Person becoming a Subsidiary of the Company or such merger or consolidation
and do not extend to any assets other than those of the Person that becomes a Subsidiary of the Company or the property, shares of stock or other assets acquired in the merger with or into or consolidation with the Company or any Subsidiary of the
Company; 
 (4) Liens on property (including Capital Stock) or other assets existing at the time of acquisition of such property or assets
by the Company or any Subsidiary of the Company; provided that such Liens were in existence prior to such acquisition and not incurred in contemplation of, such acquisition; 

(5) Liens to secure the performance of statutory obligations, insurance, surety or appeal bonds, workers compensation obligations, performance
bonds or other obligations of a like nature incurred in the ordinary course of business (including Liens to secure letters of credit issued to assure payment of such obligations) and any Liens in favor of, or required by contracts with, governmental
entities; 
 (6) Liens to secure Indebtedness represented by mortgage financings, capital leases or purchase money obligations; 

(7) Liens existing on the date of this Supplemental Indenture (with the exception of Liens securing the Credit Agreement on the date of the
Indenture which shall be deemed to be incurred pursuant to clause (1) of this definition); 

  
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 (8) extensions, renewals, alterations, refinancings or replacements of any Lien referred to
in the preceding clauses (3) through (7) above; provided, however, that (i) the principal amount of Indebtedness secured thereby shall not exceed the principal amount of Indebtedness so secured at the time of such extension,
renewal, alteration or replacement plus accrued and unpaid interest thereon together with any reasonable fees, premiums (including tender premiums) and expenses relating to such extension, renewal, alteration or replacement and (ii) such
extension, renewal, alteration, refinancing or replacement shall be limited to all or a part of the property or assets which secured the Lien so extended, renewed, altered or replaced (plus improvements on such property or assets); 

(9) Liens for taxes, assessments or governmental charges or claims that are not yet overdue for a period of 30 days or that are being
contested in good faith by appropriate proceedings; provided that any reserve or other appropriate provision as is required in conformity with GAAP has been made therefor; 

(10) Liens imposed by law, such as carriers’, warehousemen’s, landlord’s and mechanics’ Liens, in each case, incurred in
the ordinary course of business; 
 (11) survey exceptions, easements or reservations of, or rights of others for, licenses, rights-of-way, sewers, electric lines, telegraph and telephone lines and other similar purposes, or zoning or other restrictions as to the use of real property that were not
incurred in connection with Indebtedness and that do not in the aggregate materially adversely affect the value of said properties or materially impair their use in the operation of the business of such Person; 

(12) Liens created for the benefit of (or to secure) the Notes (or the Guarantees); 

(13) Liens on insurance policies and proceeds thereof, or other deposits, to secure insurance premium financings; 

(14) filing of Uniform Commercial Code financing statements as a precautionary measure in connection with operating leases; 

(15) bankers’ Liens, rights of setoff, Liens arising out of judgments or awards not constituting an Event of Default and notices of
lis pendens and associated rights related to litigation being contested in good faith by appropriate proceedings and for which adequate reserves have been made; 

(16) Liens on cash, Cash Equivalents or other property arising in connection with the defeasance, discharge or redemption of Indebtedness;

 (17) Liens on specific items of inventory or other goods (and the proceeds thereof) of any Person securing such Person’s obligations
in respect of bankers’ acceptances issued or created in the ordinary course of business for the account of such Person to facilitate the purchase, shipment or storage of such inventory or other goods; 

(18) (a) leases, subleases, licenses or sublicenses granted to others in the ordinary course of business which do not materially interfere
with the ordinary conduct of the business of the Company or any of its Subsidiaries and do not secure any Indebtedness and (b) grants of software and other technology licenses in the ordinary course of business; 

(19) Liens arising out of conditional sale, title retention, consignment or similar arrangements for the sale of goods entered into in the
ordinary course of business; 

  
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 (20) Liens securing Indebtedness of Foreign Subsidiaries that relate solely to the Equity
Interests or assets of Foreign Subsidiaries; 
 (21) Liens in favor of customs and revenue authorities arising as a matter of law to secure
payment of customs duties in connection with the importation of goods in the ordinary course of business; 
 (22) Liens (a) of a
collection bank arising under Section 4-210 of the Uniform Commercial Code on items in the course of collection, (b) attaching to commodity trading accounts or other brokerage accounts incurred in
the ordinary course of business, and (c) in favor of banking institutions arising as a matter of law encumbering deposits (including the right of set-off); 

(23) Liens that are contractual rights of set-off (a) relating to pooled deposit or sweep
accounts of the Company or any of its Subsidiaries to permit satisfaction of overdraft or similar obligations incurred in the ordinary course of business of the Company and its Subsidiaries or (b) relating to purchase orders and other
agreements entered into with customers of the Company or any of its Subsidiaries in the ordinary course of business; 
 (24) Liens securing
Hedging Obligations entered into in the ordinary course of business and not for speculative purposes; 
 (25) Liens incurred in the ordinary
course of business of the Company or any Subsidiary of the Company with respect to obligations that do not exceed, as of any date of incurrence, the greater of (a) $160.0 million and (b) 25% of Consolidated EBITDA; and 

(26) Liens on accounts receivable and related assets granted in connection with any Permitted Receivables Facility. 

For purposes of determining compliance with this definition, (x) a Lien need not be incurred solely by reference to one category of
Permitted Liens described in this definition, but may be incurred under any combination of such categories (including in part under one such category and in part under any other such category), (y) in the event that a Lien (or any portion thereof)
meets the criteria of one or more of such categories of Permitted Liens, the Company shall, in its sole discretion, classify or reclassify such Lien (or any portion thereof) in any manner that complies with this definition and (z) Liens
permitted to be incurred pursuant to Section 4.05 shall not be considered Permitted Liens under the Indenture, except for any Liens incurred pursuant to clause (1)(a) of the definition of “Permitted Liens,” which the Company shall not
be permitted to reclassify. 
 “Permitted Receivables Facility” means any of one or more receivables financing
facilities (and any guarantee of such financing facility), as amended, supplemented, modified, extended, renewed, restated, or refunded from time to time, the obligations of which are non-recourse (except for
customary representations, warranties, covenants, and indemnities made in connection with such facilities) to the Company and/or any Subsidiary (other than a Receivables Subsidiary) pursuant to which the Company and/or any Subsidiary sells, directly
or indirectly, grants a security interest in or otherwise transfers its accounts receivable to either (i) a Person that is not a Subsidiary or (ii) a Receivables Subsidiary that in turn funds such purchase by purporting to sell its
accounts receivable to a Person that is not a Subsidiary or by borrowing from such a Person or from another Receivables Subsidiary that in turn funds itself by borrowing from such a Person. 

“Person” means any individual, corporation, partnership, joint venture, association, joint-stock company, trust,
unincorporated organization, limited liability company or government or other entity. 

  
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 “Physical Notes” means certificated Notes that are not in global
form and are registered in the name of the Holder and issued in denominations of $2,000 principal amount and integral multiples of $1,000 in excess thereof. 

“Public Company Costs” means Charges associated with, or in anticipation of, or preparation for, compliance with the
requirements of the Sarbanes-Oxley Act of 2002 and the rules and regulations promulgated in connection therewith and Charges relating to compliance with the provisions of the Securities Act and the Exchange Act (and in the case of any requirement of
law, any similar requirement of law under any other applicable jurisdiction), as applicable to companies with equity or debt securities held by the public, the rules of national securities exchange companies with listed equity or debt securities,
directors’, managers’ and/or employees’ compensation, fees and expense reimbursement, Charges relating to investor relations, shareholder meetings and reports to shareholders or debtholders, directors’ and officers’
insurance and other executive costs, legal and other professional fees (including auditors’ and accountants’ fees), listing fees, filing fees and other costs and/or expenses associated with being a public company. 

“Rating Agencies” means Moody’s and S&P, or if Moody’s or S&P or both shall not make a rating on the
Notes publicly available, a nationally recognized statistical rating agency or agencies, as the case may be, selected by the Company, which shall be substituted for Moody’s or S&P or both, as the case may be. 

“Ratings Decline Period” means the period that (i) begins on the earlier of (a) a Change of Control or
(b) the first public notice of the intention by the Company to affect a Change of Control and (ii) ends 30 days following the consummation of such Change of Control; provided that such period will be extended so long as the rating
of the Notes is under publicly announced consideration for a possible downgrade by either of the Rating Agencies). 
 “Ratings
Event” means (i) a downgrade by one or more gradations (including gradations within ratings categories, as well as between rating categories) or withdrawal of the rating of the Notes within the Ratings Decline Period by each of the
Rating Agencies (unless the applicable Rating Agency shall have put forth a written statement to the effect that such downgrade or withdrawal is not attributable in whole or in part to the applicable Change of Control) and (ii) the Notes do not
have an Investment Grade rating from any of the Rating Agencies. 
 “Receivables Subsidiary” means any subsidiary
formed for the purpose of facilitating or entering into one or more Permitted Receivables Facilities, and in each case engages only in activities reasonably related or incidental thereto or another Person formed for the purposes of engaging in a
Permitted Receivables Facility in which the Company and/or any subsidiary makes an investment and to which the Company and/or any subsidiary transfers accounts receivables and related assets. 

“Refinancing Transactions” means the issuance of the Notes offered hereby, the use of the net proceeds therefrom as
described under the caption “Use of proceeds” in the Offering Memorandum and other transactions in connection therewith or incidental thereto. 

“Registrar” has the meaning specified in Section 2.4 of the Original Indenture with respect to the register with
respect to the Notes. 
 “Regular Record Date” means, with respect to the payment of interest on the Notes, the
January 1 (whether or not a Business Day) immediately preceding an Interest Payment Date on January 15 and the July 1 (whether or not a Business Day) immediately preceding an Interest Payment Date on July 15. 

  
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 “S&P” means Standard & Poor’s Ratings Services,
and any successor to its rating agency business. 
 “Significant Subsidiary” means any Subsidiary that would be a
“significant subsidiary” as defined in Article 1, Rule 1-02 of Regulation S-X, promulgated pursuant to the Securities Act, as such Regulation is in effect on
the date of this Supplemental Indenture. 
 “Sponsors” means, collectively, Advent and THL, their respective
controlled Affiliates and funds managed or advised by any of them or any of their respective controlled Affiliates (in each case, other than any portfolio company). 

“Stated Maturity” means, with respect to any installment of interest or principal on any series of Indebtedness, the
date on which the payment of interest or principal was scheduled to be paid in the documentation governing such Indebtedness as of the date of this Supplemental Indenture, and will not include any contingent obligations to repay, redeem or
repurchase any such interest or principal prior to the date originally scheduled for the payment thereof. 

“Subsidiary” means, with respect to any specified Person: 

(1) any corporation, association or other business entity of which more than 50% of the total voting power of shares of Capital Stock entitled
(without regard to the occurrence of any contingency and after giving effect to any voting agreement or stockholders’ agreement that effectively transfers voting power) to vote in the election of directors, managers or trustees of the
corporation, association or other business entity is at the time owned or controlled, directly or indirectly, by that Person or one or more of the other Subsidiaries of that Person (or a combination thereof); and 

(2) any partnership or limited liability company of which (a) more than 50% of the capital accounts, distribution rights, total equity
and voting interests or general and limited partnership interests, as applicable, are owned or controlled, directly or indirectly, by such Person or one or more of the other Subsidiaries of that Person or a combination thereof, whether in the form
of membership, general, special or limited partnership interests or otherwise, and (b) such Person or any Subsidiary of such Person is a controlling general partner or otherwise controls such entity. 

Notwithstanding the foregoing, any subsidiary that is a special purpose entity used for any permitted securitization or receivables facility
or financing (including any Receivables Subsidiary) shall not be a Subsidiary. 
 “Successor Company” has the
meaning specified in Section 5.02. 
 “Supplemental Indenture” has the meaning specified in the first paragraph
hereof. 
 “Surviving Guarantor” has the meaning specified in Section 9.05. 

“Taxes” means all present and future taxes, levies, imposts, duties, deductions, withholdings (including backup
withholding), assessments, fees or other charges imposed by any governmental authority, including any interest, additions to tax or penalties applicable thereto. 

“THL” means Thomas H. Lee Partners, L.P. and its Affiliates. 

“TIA” means the Trust Indenture Act of 1939, as amended. 

  
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 “Total Assets” means the total assets of the Company and the
Subsidiaries, as shown on the most recent balance sheet of the Company for the then most recently ended Fiscal Quarter for which financial statements are available immediately preceding the date of determination, with such adjustments to Total
Assets as are consistent with the pro forma adjustment provisions set forth in the definition of “Consolidated Net Secured Leverage Ratio.” 

“Transaction Costs” means the costs, fees, expenses and premiums associated with the Refinancing Transactions. 

“Treasury Rate” means, with respect to any redemption date with respect to any Note being redeemed pursuant to
Section 3.03(d), the yield to maturity as of the earlier of (a) such redemption date or (b) the date on which such Notes are defeased or satisfied and discharged of United States Treasury securities with a constant maturity (as
compiled and published in the most recent Federal Reserve Statistical Release H.15 (519) that has become publicly available at least two business days prior to the redemption date, or the date of defeasance or satisfaction and discharge (or, if such
Statistical Release is no longer published, any publicly available source of similar market data)) most nearly equal to the period from the redemption date, or the date of defeasance or satisfaction and discharge, to January 15, 2024;
provided, however, that if the period from the redemption date, or the date of defeasance or satisfaction and discharge, to January 15, 2024, is less than one year, the weekly average yield on actually traded United States Treasury
securities adjusted to a constant maturity of one year will be used. 
 “Trustee” has the meaning set forth in the
first paragraph of this Supplemental Indenture. 
 “U.S.” means the United States of America. 

“Voting Stock” of any specified Person as of any date means the Capital Stock of such Person that is at the time
entitled to vote in the election of the Board of Directors of such Person. 
 “Wholly-Owned Subsidiary” of any
Person means a Subsidiary of such Person, 100% of the outstanding Capital Stock or other ownership interests of which (other than directors’ qualifying shares) shall at the time be owned by such Person or by one or more Wholly-Owned
Subsidiaries of such Person. 
 ARTICLE 2. 

THE NOTES 
 Section 2.01 Title and
Terms; Payments.  
 There is hereby established a series of Securities designated the “3.625% Senior Notes due
2029” initially limited in aggregate principal amount to $600,000,000, which amount shall be as set forth in a Company Order for the authentication and delivery of Notes pursuant to Section 2.3 of the Original Indenture. 

The principal amount of Notes then Outstanding shall be payable at the Stated Maturity, which shall be January 15, 2029. Interest on the
Notes shall accrue at a rate of 3.625% per annum, from the Issue Date or from the most recent date on which interest has been paid or duly provided for, until the principal thereof is paid or made available for payment. Interest shall be payable
semi-annually in arrears on each Interest Payment Date, beginning on July 15, 2021, to the person in whose name a Note is registered on the Register at 5:00 p.m., New York City time, on the Regular Record Date immediately preceding the
applicable Interest Payment Date. Interest will be computed on the basis of a 360-day year comprised of twelve 30-day months. If any interest payment date, the maturity
date, any redemption date, or any earlier required repurchase date of a Note falls on a day that is not a business day, the required payment will be made on the next succeeding business day and no interest on such payment will accrue in respect of
the delay. 

  
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 The Company may, at its election and without notice to or the consent of the Holders of the
Notes, hereafter issue additional Notes (“Additional Notes”) under the Indenture with the same terms and with the same CUSIP numbers as the Notes issued on the date of this Supplemental Indenture (the “Initial
Notes”) in an unlimited aggregate principal amount. The Initial Notes and such Additional Notes, if any, will be treated as a single class for all purposes of the Indenture, including, without limitation, waivers, amendments,
redemptions and offers to purchase; provided that, if any such Additional Notes subsequently issued are not fungible for U.S. federal income tax purposes or securities law purposes with any Notes previously issued, such Additional Notes shall
trade separately from such previously issued Notes under a separate CUSIP number but shall otherwise be treated as a single class with all other Notes issued under the Indenture. 

Provisions relating to the Notes are set forth in Appendix A hereto (the “Appendix”), which is hereby incorporated in
an expressly made a part of this Supplemental Indenture. The terms and provisions contained in the Appendix and the Notes shall constitute, and are hereby expressly made, a part of this Supplemental Indenture, and the Company and the Trustee, by
their execution and delivery of this Supplemental Indenture, expressly agree to such terms and provisions and to be bound thereby. However, to the extent any provision of any Note or any notation of Guarantees thereon conflicts with the express
provisions of this Supplemental Indenture, the provisions of this Supplemental Indenture shall govern and be controlling. 
 Notes issued in
global form shall be substantially in the form of Exhibit A attached hereto (including the Global Notes Legend). Notes issued in definitive form shall be substantially in the form of Exhibit A attached hereto (but without the Global
Notes Legend and without the “Schedule of Exchanges of Interests in the Global Note” attached thereto). Each Global Note shall represent such aggregate principal amount of the outstanding Notes as shall be specified therein and each shall
provide that it shall represent the aggregate principal amount of outstanding Notes from time to time endorsed thereon and that the aggregate principal amount of outstanding Notes represented thereby may from time to time be reduced or increased, as
appropriate, to reflect exchanges and redemptions. Any endorsement of a Global Note to reflect the amount of any increase or decrease in the aggregate principal amount of outstanding Notes represented thereby shall be made by the Trustee, the
Depositary or the Note Custodian, at the direction of the Trustee, in accordance with written instructions given by the Holder thereof as required by Section 2.7 of the Original Indenture. 

The Company shall pay the principal of and interest on any Global Note in immediately available funds to the Depository or its nominee, as the
case may be, as the registered Holder of such Global Note. The Company, through the Paying Agent, shall make all payments of principal, premium, if any, and interest, with respect to Physical Notes by wire transfer of immediately available funds to
the accounts specified by the Holders of the Physical Notes or, if no such account is specified, by mailing a check to each such Holder’s registered address. The Company has initially designated the Trustee as its Paying Agent and its Registrar
in respect of the Notes. The Company may, however, change the Paying Agent or the Registrar for the Notes without prior notice to the Holders thereof, and the Company or one of its Subsidiaries may act as the Paying Agent or the Registrar for the
Notes. 
 A Holder may transfer or exchange Notes at the office of the Registrar in accordance with Section 2.7 of the Original
Indenture. 
 Section 2.02 Repurchase and Cancellation. To the extent permitted by law, the Company may at any time and from time
to time repurchase Notes in open market purchases or by tender at any price or in negotiated transactions without giving prior notice to Holders. The Company shall surrender any Notes repurchased by the Company to the Trustee for cancellation in
accordance with Section 2.12 of the Original Indenture and any such Notes repurchased by the Company shall be deemed to be no longer Outstanding. Any Notes surrendered for cancellation by the Company shall not be reissued or resold. 

  
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 ARTICLE 3. 

REDEMPTION AND PREPAYMENT 

Section 3.01 Notice of Redemption. 

(a) Notwithstanding Section 3.3 of the Original Indenture, notices of redemption will be delivered electronically in portable document
format (“pdf”) or mailed by first class mail at least 10 but not more than 60 days before the redemption date to each holder of Notes to be redeemed at its registered address or otherwise in accordance with the procedures of DTC, except
that redemption notices may be mailed more than 60 days prior to a redemption date if the notice is issued in connection with a defeasance of the Notes or a satisfaction and discharge of the Indenture. 

Section 3.02 Effect of Notice of Redemption. 

(a) Notwithstanding Section 3.4 of the Original Indenture, any notice of redemption may, at the Company’s discretion, be subject to
one or more conditions precedent, including, but not limited to, availability of borrowings under any Credit Facility, completion of a sale of common stock or other securities offering or corporate transaction. Once notice of redemption is provided
in accordance with the Indenture, Notes called for redemption become irrevocably due and payable on the redemption date at the redemption price, subject only to the satisfaction or waiver of any conditions precedent. 

(b) If such notice of redemption is subject to satisfaction of one or more conditions precedent, such notice shall state that, in the
Company’s discretion, the redemption date may be delayed until such time as any or all such conditions shall be satisfied (which, for the avoidance of doubt, may be later than 60 days from the date such notice was delivered or mailed), or such
redemption may not occur and such notice may be rescinded in the event that any or all such conditions shall not have been satisfied by the redemption date, or by the redemption date so delayed. 

Section 3.03 Optional Redemption. 

(a) At any time prior to July 15, 2023, the Company may on any one or more occasions redeem up to 40% of the aggregate principal amount of
Notes issued under this Supplemental Indenture (including any Additional Notes), upon not less than 10 nor more than 60 days’ notice, at a redemption price equal to 103.625% of the principal amount of the Notes redeemed, plus accrued and unpaid
interest, if any, to, but not including, the date of redemption (subject to the rights of Holders of Notes on the relevant record date to receive interest on the relevant interest payment date), with the net cash proceeds of an Equity Offering;
provided that: 
 (1) at least 60% of the aggregate principal amount of Notes originally issued under this Supplemental Indenture on
the date of this Supplemental Indenture remains outstanding after each such redemption (excluding Notes held by the Company and its Subsidiaries), unless all such Notes are repurchased or redeemed substantially concurrently; and 

(2) the redemption occurs within 180 days of the date of the closing of such Equity Offering. 

  
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 (b) At any time prior to January 15, 2024, the Company may on any one or more occasions
redeem all or a part of the Notes, upon not less than 10 nor more than 60 days’ notice, at a redemption price equal to 100% of the principal amount of the Notes redeemed, plus the Applicable Premium as of, and accrued and unpaid interest, if
any, to, but not including, the date of redemption, subject to the rights of Holders of Notes on the relevant record date to receive interest due on the relevant interest payment date. 

(c) Except pursuant to Sections 3.03(a) and (b), the Notes will not be redeemable at the Company’s option prior to January 15, 2024.

 (d) On or after January 15, 2024, the Company may on any one or more occasions redeem all or a part of the Notes, upon not less than
10 nor more than 60 days’ notice, at the redemption prices (expressed as percentages of principal amount) set forth below, plus accrued and unpaid interest, if any, on the Notes redeemed, to, but not including, the applicable date of
redemption, if redeemed during the twelve-month period beginning on January 15 of the years indicated below, subject to the rights of Holders of Notes on the relevant record date to receive interest due on the relevant interest payment date:

  

					
	 Year
	  	Percentage	 
	 2024
	  	 	101.813	% 
	 2025
	  	 	100.906	% 
	 2026 and thereafter
	  	 	100.000	% 

 Unless the Company defaults in the payment of the redemption price, interest will cease to accrue on the Notes
or portions thereof called for redemption on the applicable redemption date. 
 (e) If less than all of the Notes are to be redeemed at any
time, the Trustee will select Notes for redemption on a pro rata basis or, in the case of Global Notes, based on a method that most nearly approximates a pro rata selection as the Trustee deems fair and appropriate and in accordance
with the applicable procedures of the Depository unless otherwise required by law or applicable stock exchange or depositary requirements. 

(f) No Notes of $2,000 or less shall be redeemed in part. 

(g) Any redemption pursuant to this Section 3.03 shall be made pursuant to the provisions of Sections 3.01 and 3.02 hereof and Sections
3.1, 3.3, 3.5 and 3.6 of the Original Indenture. 
 (h) Notwithstanding the foregoing, in connection with any tender offer for the Notes,
including a Change of Control Offer, if Holders of not less than 90% in aggregate principal amount of the outstanding Notes validly tender and do not withdraw such Notes in such tender offer and the Company or any third party making such tender
offer in lieu of the Company, purchases all of the Notes validly tendered and not withdrawn by such holders, the Company or such third party will have the right upon not less than 10 nor more than 60 days’ prior notice, given not more than 10
days following such purchase date, to redeem all Notes that remain outstanding following such purchase at a redemption price equal to the price offered to each other holder in such tender offer plus, to the extent not included in the tender offer
payment, accrued and unpaid interest, if any, thereon, to, but not including, the date of such redemption. 
 (i) If any Note is to be
redeemed in part only, the notice of redemption that relates to that Note will state the portion of the principal amount of that Note that is to be redeemed. No Notes of $2,000 or less in principal amount will be redeemed in part. A new Note in
principal amount equal to the unredeemed portion of the original Note will be issued in the name of the Holder of Notes upon cancellation of the original Note. Notes called for redemption become due on the date fixed for redemption, unless such
redemption is conditioned on the happening of a future event. On the redemption date, interest ceases to accrue on Notes or portions of Notes redeemed unless the Company defaults in paying the applicable redemption price. 

  
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 Section 3.04 [Reserved].  

Section 3.05 Mandatory Redemption. 

The Company is not required to make mandatory redemption or sinking fund payments with respect to the Notes. 

ARTICLE 4. 
 COVENANTS

 Section 4.01 Reports. 
 (a)
Whether or not required by the rules and regulations of the SEC, so long as any Notes are outstanding, the Company shall provide to the Trustee copies of the annual reports and of the information, documents and other reports (or copies of such
portions of any of the foregoing as the SEC may from time to time by rules and regulations prescribe) that the Company would be required to file with the SEC pursuant to Section 13 or Section 15(d) of the Exchange Act, subject to the next
succeeding paragraph. The company shall be deemed to have complied with the previous sentence to the extent that such information, documents and reports are filed with the SEC via EDGAR, or any successor electronic delivery procedure. 

(b) If, at any time, the Company is no longer subject to the periodic reporting requirements of the Exchange Act for any reason, with respect
to the information, documents and reports provided for in the immediately preceding paragraph: (i) with respect to current reports on Form 8-K under the SEC’s rules and regulations, the Company shall
be required to provide only current reports containing substantially all of the information that would be required to be filed in a current report on Form 8-K under the Exchange Act on the Issue Date pursuant
to Sections 1, 2 and 4, Items 5.01, 5.02(a)-(c) (other than compensation information) and Item 9.01 (only to the extent relating to any of the foregoing) of Form 8-K; provided, however, that no such
current reports (or Items thereof or all or a portion of the financial statements that would have otherwise been required thereby) will be required to be provided (or included) if the Company determines in its good faith judgment that such event (or
information) is not material to Holders of the Notes or to the business, assets, operations or financial position of the Company and its Subsidiaries, taken as a whole; (ii) such information, documents and reports shall, in each case, be
subject to exceptions and exclusions consistent with the presentation of financial and other information in the Offering Memorandum, including with respect to the omission of financial statements or financial information required by Rules 3-09 or 3-10 under Regulation S-X promulgated by the SEC (or any successor provision), Compensation Discussion and Analysis otherwise
required by Regulation S-K Item 402(b), and information otherwise required by Section 404 of the Sarbanes-Oxley Act of 2002; (iii) trade secrets and other confidential information that is competitively
sensitive in the good faith and reasonable determination of the Company may be excluded from any information, documents and reports; (iv) in no event will such information, documents and reports will contain compensation or beneficial ownership
information; and (v) in no event will such information, documents and reports be required to comply with Regulation G under the Exchange Act or Item 10(e) of Regulation S-K promulgated by the SEC with
respect to any non-GAAP financial measures contained therein. 

  
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 (c) The Company may satisfy its obligations in this Section 4.01 with respect to
financial information relating to the Company by furnishing financial information relating to a direct or indirect parent entity; provided that if and so long as such parent entity shall have Independent Assets or Operations (as defined
below), the same is accompanied by consolidating information that explains in reasonable detail the differences between the information relating to such parent entity, on the one hand, and the information relating to the Company and its Subsidiaries
on a standalone basis, on the other hand. “Independent Assets or Operations” means, with respect to any such parent entity, that such parent entity’s total assets or revenues, determined in accordance with GAAP and as shown on the
most recent financial statements of such parent entity, is more than 5.0% of such parent entity’s corresponding consolidated amount. 

(d) Notwithstanding anything herein to the contrary, in the event that the Company fails to comply with its obligation to file or provide such
information, documents and reports as required hereunder, the Company will be deemed to have cured such Default with respect to the Notes for purposes of Section 6.01(4) upon the filing or provision of all such information, documents and
reports required hereunder prior to the expiration of 90 days after written notice to the Company of such failure from the Trustee or the Holders of at least 25% of the principal amount of the Notes. 

(e) The Trustee shall have no responsibility whatsoever to monitor whether any filing or posting contemplated by this Section 4.01 has
occurred. Delivery of any reports, information or documents pursuant to this Section 4.01 is for informational purposes only and the Trustee’s receipt of such shall not constitute constructive notice of any information contained therein or
determinable from information contained therein, including the Company’s compliance with any of its covenants hereunder (as to which the Trustee is entitled to rely exclusively on Officer’s Certificates). 

Section 4.02 [Reserved]. 
 Section 4.03
Liens. 
 (a) Except as permitted under Section 4.05, the Company will not, and will not permit any of its Subsidiaries to,
create, incur, assume or otherwise cause or suffer to exist or become effective any Lien of any kind (other than Permitted Liens) securing Indebtedness upon any of their property or assets, now owned or hereafter acquired, unless (1) in the
case of any Lien securing pari passu Indebtedness, the Notes are secured by a Lien that is senior in priority to or pari passu with such Lien and (2) in the case of any Lien securing subordinated Indebtedness, the Notes are
secured by a Lien that is senior in priority to such Lien. 
 (b) Any Lien created for the benefit of the Holders of the Notes pursuant to
Section 4.03(a) will provide by its terms that any such Lien shall be automatically and unconditionally released and discharged upon the release and discharge of the Lien on such other Indebtedness, without any further action required of the
Company, any Subsidiary or the Trustee. 
 (c) The expansion of Liens by virtue of accrual of interest, the accretion of accreted value, the
payment of interest or dividends in the form of additional Indebtedness, amortization of original issue discount and increases in the amount of Indebtedness outstanding solely as a result of fluctuations in the exchange rate of currencies or
increases in the value of property securing Indebtedness will not be deemed to be an incurrence of Liens for purposes of this Section 4.03. 

(d) For purposes of determining compliance with this Section 4.03, (i) a Lien need not be incurred solely by reference to one category of
Permitted Liens but may be incurred under any combination of such categories (including in part under one such category and in part under any other such category) and (ii) in the event that a Lien (or any portion thereof) meets the criteria of
one or more of such categories of Permitted Liens or may be incurred in compliance with the terms described under 

  
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 Section 4.05, the Company shall, in its sole discretion, classify or may subsequently reclassify at any
time such Lien (or any portion thereof) in any manner that complies with this Section 4.03 (including by complying with the terms described under Section 4.05) and the definition of Permitted Liens, except for any Liens incurred pursuant
to clause (1)(a) of the definition of “Permitted Liens,” which the Company shall not be permitted to reclassify. 
 Section 4.04 Offer to
Repurchase Upon Change of Control Triggering Event. 
 (a) If a Change of Control occurs and is accompanied by a Ratings Events
(together, a “Change of Control Triggering Event”), each Holder of Notes will have the right to require the Company to repurchase all or any part (equal to $2,000 or an integral multiple of $1,000 in excess thereof) of that
Holder’s Notes pursuant to an offer by the Company (a “Change of Control Offer”) on the terms set forth in this Supplemental Indenture. In the Change of Control Offer, the Company will offer a payment in cash equal to
101% of the aggregate principal amount of Notes repurchased, plus accrued and unpaid interest, if any, on the Notes repurchased to, but not including, the date of purchase (the “Change of Control Payment”), subject to the
rights of Holders of Notes on the relevant record date to receive interest due on the relevant interest payment date. Within thirty days following any Change of Control Triggering Event, the Company will deliver electronically in pdf format or mail
a notice to each Holder with a copy to the Trustee or otherwise in accordance with the procedures of DTC describing the transaction or transactions that constitute the Change of Control Triggering Event and offering to repurchase Notes on the date
specified in the notice, which date will be no earlier than 30 days and no later than 60 days from the date such notice is mailed or otherwise delivered (a “Change of Control Payment Date”), pursuant to the procedures
required by the Indenture and described in such notice. The Company will comply with the requirements of Rule 14e-1 under the Exchange Act and any other securities laws and regulations thereunder to the extent
those laws and regulations are applicable in connection with the repurchase of the Notes as a result of a Change of Control Offer. To the extent that the provisions of any securities laws or regulations conflict with the Change of Control Offer
provisions of the Indenture, the Company will comply with the applicable securities laws and regulations and will not be deemed to have breached its obligations under the Change of Control Offer provisions of the Indenture by virtue of such
compliance. 
 (b) On the Change of Control Payment Date, the Company will, to the extent lawful: 

(1) accept for payment all Notes or portions of Notes properly tendered pursuant to the Change of Control Offer; and 

(2) deposit with the Paying Agent an amount equal to the Change of Control Payment in respect of all Notes or portions of Notes properly
tendered. 
 The Paying Agent will promptly send to each Holder of Notes properly tendered the Change of Control Payment for such Notes, and
the Trustee will promptly authenticate and mail (or cause to be transferred by book entry in accordance with the applicable procedures of DTC) to each Holder a new Note equal in principal amount to any unpurchased portion of the Notes surrendered,
if any. The Company will publicly announce the results of the Change of Control Offer on or as soon as practicable after the Change of Control Payment Date. 

(c) The Company will not be required to make a Change of Control Offer upon a Change of Control Triggering Event if: 

  
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 (1) a third party makes the Change of Control Offer in the manner, at the times and
otherwise in compliance with the requirements set forth in the Indenture applicable to a Change of Control Offer made by the Company and purchases all Notes properly tendered and not withdrawn under the Change of Control Offer; provided,
however, in the event that such third party terminates, or defaults under, its offer, the Company will be required to make a Change of Control Offer treating the date of such termination or default as though it were the date of the Change of
Control Triggering Event; or 
 (2) notice of redemption has been given pursuant to the Indenture as described above under
Section 3.03, unless and until there is a default in payment of the applicable redemption price. 
 (d) Notwithstanding anything to the
contrary contained in this Section 4.04, a Change of Control Offer may be made in advance of a Change of Control Triggering Event, conditioned upon the consummation of such Change of Control Triggering Event, if a definitive agreement is in
place for the Change of Control at the time the Change of Control Offer is made. 
 Section 4.05 Exempted Transactions. 

(a) Notwithstanding Sections 4.03 and 4.07, the Company and any Subsidiary may (1) create, incur or assume any Lien upon any property or
assets, or (2) consummate any Sale and Lease Back Transaction, if: (i) the aggregate outstanding principal amount of all secured Indebtedness for borrowed money of the Company and its Subsidiaries that is secured by Liens on any of their
property or assets, now owned or hereafter acquired (which amount shall exclude Indebtedness secured by Liens incurred pursuant to clauses (2) through (26) of the definition of Permitted Liens (“Exempted Liens”)), plus (ii) the
aggregate Attributable Indebtedness in respect of Sale and Lease Back Transactions that is subject to the restriction on Sale and Lease Back Transactions described above does not exceed an amount that would cause the Consolidated Net Secured
Leverage Ratio for the period immediately preceding the creation, incurrence or assumption of such a Lien or consummation of such Sale and Lease Back Transaction, as applicable, to be greater than the greater of (x) 3.50 to 1.00 or (y) if such
Lien is created, incurred or assumed in connection with an acquisition or investment, the Consolidated Net Secured Leverage Ratio immediately prior to such creation, incurrence or assumption, in each case calculated on a pro forma basis consistent
with the pro forma adjustment provisions set forth in the definition of “Consolidated Net Secured Leverage Ratio,” and after giving effect to the creation, incurrence or assumption of such Lien described above and/or such Attributable
Indebtedness in respect of Sale and Lease Back Transactions that is subject to the restriction on Sale and Lease Back Transactions described above. The Company and any Subsidiary may guarantee any Lien created, incurred or assumed and any Sale and
Lease Back Transaction consummated, in each case, in compliance with the terms described in this paragraph. 
 (b) In the event any Lien is
created, incurred or assumed or any Sale and Lease Back Transaction is consummated, in each case, in reliance upon compliance with the Consolidated Net Secured Leverage Ratio described above, concurrently with creation, incurrence or assumption of
any Permitted Lien, then solely for purposes of calculating the Consolidated Net Secured Leverage Ratio at such time (but, for the avoidance of doubt, not in any subsequent calculation of the Consolidated Net Secured Leverage Ratio at a subsequent
time), the Consolidated Net Secured Leverage Ratio will be calculated without regard to the creation, incurrence or assumption of any such Permitted Lien. 

Section 4.06 Additional Guarantees. 

If the Company or any of its Subsidiaries acquires or creates another Domestic Subsidiary that is a Wholly-Owned Subsidiary after the date of
this Supplemental Indenture that guarantees or otherwise becomes an obligor with respect to any Indebtedness of the Company or any of its Subsidiaries under a Credit Facility (other than inter-company Indebtedness), then such Domestic Subsidiary
will become a Guarantor and execute a supplemental indenture and deliver an Opinion of Counsel to the Trustee within 60 business days of the date such Domestic Subsidiary guarantees or otherwise becomes an obligor with 

  
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 respect to any Indebtedness of the Company or any of its Subsidiaries under a Credit Facility; provided
that any such Domestic Subsidiary that constitutes an Immaterial Subsidiary need not become a Guarantor until such time as it ceases to be an Immaterial Subsidiary. Each Guarantee of a Domestic Subsidiary that is a Wholly-Owned Subsidiary will
provide by its terms that it will be automatically released under the circumstances described in Article 9. Beginning on the Fall Away Date and continuing at all times thereafter regardless of any subsequent changes in the ratings of the Notes, this
Section 4.06 will permanently cease to be in effect with respect to the Notes. 
 The Company may elect, in its sole discretion, to
cause any Subsidiary that is not otherwise required to be a Guarantor to become a Guarantor, in which case such Subsidiary shall not be required to comply with the 60 business day period described above. 

Section 4.07 Sale and Leaseback Transactions. 

(a) Except as permitted under Section 4.05, the Company will not, and will not permit any of its Subsidiaries to, engage in the sale or
transfer by the Company or any Subsidiary of any property to a Person (other than the Company or a Subsidiary) and the taking back by the Company or such Subsidiary, as the case may be, of a lease of such property (a “Sale and Leaseback
Transaction”) unless: 
 (1) the Company or such Subsidiary could incur Indebtedness secured by a Lien on the property to be
leased without equally and ratably securing the Notes; 
 (2) the property leased pursuant to such arrangement is sold for a price at least
equal to such property’s fair value (as determined by the Company in good faith); or 
 (3) within 365 days of the effective date of
any such Sale and Lease Back Transaction, the Company applies the Net Proceeds of the sale of the leased property, less the amount of Net Proceeds used to prepay, redeem or purchase the Notes, (i) to the prepayment or retirement of Indebtedness
of the Company and its Subsidiaries (which may include the Notes) and/or (ii) the acquisition, construction or improvement of any property or assets. 

ARTICLE 5. 
 SUCCESSORS

 Section 5.01 Merger, Consolidation or Sale of Assets. 

The provisions in Article V of the Original Indenture shall not apply with respect to the Notes, and this Article 5 supersedes the
entirety thereof. 
 (a) The Company will not, directly or indirectly: (1) consolidate or merge with or into another Person (whether or
not the Company is the surviving corporation), or (2) sell, assign, transfer, lease, convey or otherwise dispose of all or substantially all of the properties or assets of the Company and its Subsidiaries taken as a whole, in one or more
related transactions, to another Person, unless: 
 (1) either: 

(A) the Company is the surviving corporation; or 

(B) the Person formed by or surviving any such consolidation or merger (if other than the Company) or to which such sale, assignment,
transfer, lease, conveyance or other disposition has been made (the “Successor Company”) is an entity organized or existing under the laws of the United States, any state of the United States, the District of Columbia or any
territory thereof; and, if such entity is not a corporation, a co-obligor of the Notes is a corporation organized or existing under any such laws; 

  
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 (2) the Successor Company (if other than the Company) assumes all the obligations of the
Company under the Notes and this Supplemental Indenture pursuant to a supplemental indenture substantially in the form attached hereto as Exhibit B, or, in each case, pursuant to other documents or instruments reasonably satisfactory to the Trustee;
and 
 (3) immediately after such transaction, no Default or Event of Default exists. 

(b) The Successor Company will succeed to, and be substituted for, the Company under the Indenture and the Notes and the Company will
automatically be released and discharged from its obligations under the Indenture and the Notes, but in the case of a lease of all or substantially all of the properties and assets of the Company and its Subsidiaries taken as a whole, the Company
will not be released from the obligation to pay the principal of and interest on the Notes. 
 (c) Notwithstanding clause (3) of
Section 5.01(a), 
 (1) the Company or any Subsidiary may consolidate or amalgamate with or merge with or
into or transfer all or part of its properties and assets to the Company or another Subsidiary, and 
 (2) the
Company may merge with or into an Affiliate solely for the purpose of reincorporating the Company in another jurisdiction. 
 Section 5.02 Successor
Corporation Substituted. 
 In case of any such consolidation, merger, sale, conveyance, transfer, lease or other disposition set forth
in Section 5.01, in which the Company is not the Successor Company and upon the assumption by the Successor Company by supplemental indenture executed and delivered to the Trustee of the due and punctual payment of the principal of and interest
on all of the Notes, and the due and punctual performance and observance of all of the covenants and conditions of this Supplemental Indenture to be performed or satisfied by the Company, such Successor Company shall succeed to, and be substituted
for, and may exercise every right and power of, the Company under this Supplemental Indenture, with the same effect as if it had been named herein as the party of this first part, and the Company shall be discharged from its obligations under the
Notes and this Supplemental Indenture, except in the case of any such lease, as provided in Section 5.01(b). Such Successor Company thereupon may cause to be signed, and may issue either in its own name or in the name of the Company any or all
of the Notes, issuable hereunder that theretofore shall not have been signed by the Company and delivered to the Trustee; and, upon the order of such Successor Company instead of the Company and subject to all the terms, conditions and limitations
in this Supplemental Indenture prescribed, the Trustee shall authenticate and shall deliver, or cause to be authenticated and delivered, any Notes that previously shall have been signed and delivered by the officers of the Company to the Trustee for
authentication, and any Notes that such Successor Company thereafter shall cause to be signed and delivered to the Trustee for that purpose. All the Notes so issued shall in all respects have the same legal rank and benefit under this Supplemental
Indenture as the Notes theretofore or thereafter issued in accordance with the terms of this Supplemental Indenture as though all of such Notes had been issued at the date of the execution hereof. In the event of any such consolidation, merger,
sale, conveyance, transfer or other disposition upon compliance with this Article 5 the person named as the “Company” in the first paragraph of this Supplemental Indenture or any successor that shall thereafter have become such in the
manner prescribed in this Article 5 may be dissolved, wound up and liquidated at any time thereafter and such person shall be discharged from its liabilities as obligor and maker of the Notes and from its obligations under this Supplemental
Indenture with respect to the Notes. 

  
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 Section 5.03 Opinion of Counsel to Be Given to Trustee. Prior to execution of any
supplemental indenture pursuant to this Article 5, the Trustee shall receive an Officer’s Certificate and an Opinion of Counsel in accordance with Section 12.4 of the Original Indenture as conclusive evidence that consolidation, merger,
sale, conveyance, transfer, lease or other disposition set forth in Section 5.01 and any such assumption complies with the provisions of this Article 5. 

ARTICLE 6. 
 DEFAULT AND
REMEDIES 
 Section 6.01 Events of Default.  

Sections 6.7, 6.9, 6.10 and 6.11 in Article VI of the Original Indenture shall apply with respect to the Notes, and this Article 6 supersedes
the remaining sections thereof. 
 Each of the following events shall be an “Event of Default” wherever used herein with
respect to the Notes, and, except to the extent set forth in this Section 6.01, the Notes shall not have the benefit of any “Event of Default” specified in Section 6.1 of the Original Indenture: 

(1) default for 30 days in the payment when due of interest on the Notes; 

(2) default in the payment when due (at maturity, upon redemption or otherwise) of the principal of, or premium, if any, on, the Notes; 

(3) failure by the Company or any of its Subsidiaries to comply with the provisions described under Article 5 for 30 days after notice to the
Company by the Trustee or the Holders of at least 25% in aggregate principal amount of the Notes then outstanding; 
 (4) failure by the
Company or any of its Subsidiaries for 60 days (90 days in the case of the provisions set forth in Section 4.01 hereof) after notice to the Company by the Trustee or the Holders of at least 25% in aggregate principal amount of the Notes then
outstanding to comply with any of the other agreements in the Indenture; 
 (5) default with respect to any mortgage, agreement or other
instrument under which there may be outstanding, or by which may be secured or evidenced any Indebtedness for money borrowed in excess of $150.0 million in the aggregate by the Company or any of its Subsidiaries, whether such Indebtedness or
Guarantee now exists, or is created after the date of this Supplemental Indenture, if that default: 
 (a) constitutes a failure to pay the
principal or interest of any such Indebtedness or Guarantee when due and payable at its Stated Maturity, upon required repurchase, upon declaration or otherwise (subject to any applicable grace period); or 

(b) results in such Indebtedness becoming or being declared due and payable; 

(6) failure by the Company or any of its Subsidiaries to pay final judgments entered by a court or courts of competent jurisdiction
aggregating in excess of $150.0 million, which judgments are not paid, discharged or stayed, for a period of 60 days; 

  
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 (7) prior to the Fall Away Date, except as permitted by the Indenture, any Guarantee of any
Guarantor that is a Significant Subsidiary (or any group of Guarantors that, taken together, as of the latest audited consolidated financial statements for the Company would constitute a Significant Subsidiary) is held in any judicial proceeding to
be unenforceable or invalid or ceases for any reason to be in full force and effect, or any Guarantor that is a Significant Subsidiary, or any group of Guarantors that, taken together, would constitute a Significant Subsidiary, or any Person acting
on behalf of any such Guarantor or group of Guarantors, denies or disaffirms its obligations under its Guarantee; and 
 (8) the Company or
any of its Subsidiaries that is a Significant Subsidiary or any group of Subsidiaries of the Company that, taken together, would constitute a Significant Subsidiary: 

(a) commences a voluntary case, 

(b) consents to the entry of an order for relief against it in an involuntary case, 

(c) consents to the appointment of a custodian of it or for all or substantially all of its property, 

(d) makes a general assignment for the benefit of its creditors, or 

(e) generally is not paying its debts as they become due 

in each case, pursuant to or within the meaning of Bankruptcy Law; or 

(9) a court of competent jurisdiction enters an order or decree under any Bankruptcy Law that: 

(a) is for relief against the Company or any of its Subsidiaries that is a Significant Subsidiary or any group of Subsidiaries of the Company
that, taken together, would constitute a Significant Subsidiary in an involuntary case; 
 (b) appoints a custodian of the Company or any of
its Subsidiaries that is a Significant Subsidiary or any group of Subsidiaries of the Company that, taken together, would constitute a Significant Subsidiary or for all or substantially all of the property of the Company or any of its Subsidiaries
that is a Significant Subsidiary or any group of Subsidiaries of the Company that, taken together, would constitute a Significant Subsidiary; or 

(c) orders the liquidation of the Company or any of its Subsidiaries that is a Significant Subsidiary or any group of Subsidiaries of the
Company that, taken together, would constitute a Significant Subsidiary; 
 and the order or decree remains unstayed and in effect for 60
consecutive days. 
 So long as any of the Notes are outstanding, the Company will deliver to the Trustee, within 30 days of any Officer
becoming aware of any Default or Event of Default that is continuing, an Officer’s Certificate specifying such Default or Event of Default and what action the Company is taking or proposes to take with respect thereto. 

  
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 Section 6.02 Acceleration.  

In the case of an Event of Default specified in clause (8) or (9) of Section 6.01, with respect to the Company, any Subsidiary of
the Company that is a Significant Subsidiary or any group of Subsidiaries of the Company that, taken together, would constitute a Significant Subsidiary, all outstanding Notes will become due and payable immediately without further action or notice.
If any other Event of Default occurs and is continuing, the Trustee or the Holders of at least 25% in aggregate principal amount of the then outstanding Notes may declare all the Notes to be due and payable immediately. Upon any such declaration,
the Notes shall become due and payable immediately. 
 The Holders of a majority in aggregate principal amount of the then outstanding Notes
by written notice to the Trustee may, on behalf of all of the Holders of all the Notes, rescind an acceleration or waive any existing Default or Event of Default and its consequences under the Indenture, if the rescission would not conflict with any
judgment or decree, except a continuing Default or Event of Default in the payment of principal of, premium on, if any, or interest on the Notes. 

Section 6.03 Other Remedies. 
 If an
Event of Default occurs and is continuing, the Trustee may pursue any available remedy to collect the payment of principal of, premium on, if any, or interest, if any, on, the Notes or to enforce the performance of any provision of the Notes or the
Indenture. 
 The Trustee may maintain a proceeding even if it does not possess any of the Notes or does not produce any of them in the
proceeding. A delay or omission by the Trustee or any Holder of a Note in exercising any right or remedy accruing upon an Event of Default shall not impair the right or remedy or constitute a waiver of or acquiescence in the Event of Default. All
remedies are cumulative to the extent permitted by law. 
 Section 6.04 Waiver of Past Defaults. 

The Holders of a majority in aggregate principal amount of the then outstanding Notes by written notice to the Trustee may, on behalf of the
Holders of all of the Notes waive any existing Default or Event of Default and its consequences hereunder, except a continuing Default or Event of Default in the payment of principal of, premium on, if any, or interest on, the Notes (including in
connection with an offer to purchase); provided, however, that the Holders of a majority in aggregate principal amount of the then outstanding Notes may rescind an acceleration and its consequences, including any related payment default that
resulted from such acceleration. Upon any such waiver, such Default shall cease to exist, and any Event of Default arising therefrom shall be deemed to have been cured for every purpose of the Indenture with respect to the Notes; but no such waiver
shall extend to any subsequent or other Default or impair any right consequent thereon. 
 In the event of any Event of Default specified in
Section 6.01(5), such Event of Default and all consequences thereof (excluding any resulting payment default, other than as a result of acceleration of the Notes) shall be annulled, waived and rescinded, automatically and without any action by
the Trustee or the Holders, if within 30 days after such Event of Default arose: (1) the Indebtedness or Guarantee that is the basis for such Event of Default has been discharged; or (2) Holders thereof have rescinded or waived the
acceleration, notice or action (as the case may be) giving rise to such Event of Default; or (3) the default that is the basis for such Event of Default has been cured. 

A notice of an Event of Default may not be given with respect to any action reported publicly or to Holders, more than two years prior to such
notice of an Event of Default. 

  
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 Section 6.05 Control by Majority. 

Holders of a majority in principal amount of the then outstanding Notes may direct the time, method and place of conducting any proceeding for
exercising any remedy available to the Trustee or of exercising any trust or power conferred on the Trustee. The Trustee, however, may refuse to follow any direction that conflicts with law or the Indenture that the Trustee determines is unduly
prejudicial to the rights of any other Holders (it being understood that the Trustee does not have the affirmative duty to ascertain whether or not any such directions are unduly prejudicial to such Holders) of a Note or that could result in
personal liability for the Trustee. 
 Section 6.06 Limitation on Suits. 

In case an Event of Default occurs and is continuing, the Trustee will be under no obligation to exercise any of the rights or powers under the
Indenture at the request or direction of any Holders of Notes unless such Holders have offered to the Trustee indemnity or security satisfactory to the Trustee against any loss, liability or expense. Except to enforce the right to receive payment of
principal, premium, if any, or interest when due, no Holder of a Note may pursue any remedy with respect to the Indenture or the Notes unless: 
  

	(1)	 such Holder has previously given the Trustee written notice that an Event of Default is continuing;



  

	(2)	 Holders of at least 25% in aggregate principal amount of the then outstanding Notes make a written request to
the Trustee to pursue the remedy; 


  

	(3)	 such Holder or Holders offer and, if requested, provide to the Trustee security or indemnity satisfactory to
the Trustee against any loss, liability or expense; 


  

	(4)	 the Trustee does not comply with such request within 60 days after receipt of the request and the offer of
security or indemnity; and 


  

	(5)	 during such 60-day period, Holders of a majority in aggregate principal
amount of the then outstanding Notes do not give the Trustee a direction inconsistent with such request. 


 Section 6.07
Collection Suit by Trustee. 
 If an Event of Default specified in Section 6.01(1) or (2) hereof occurs and is continuing,
the Trustee is authorized to recover judgment in its own name and as Trustee of an express trust against the Company for the whole amount of principal of, premium on, if any, and interest remaining unpaid on, the Notes and interest on overdue
principal and, to the extent lawful, interest and such further amount as shall be sufficient to cover the costs and expenses of collection, including the reasonable compensation, expenses, disbursements and advances of the Trustee, its agents and
counsel. 
 ARTICLE 7. 

LEGAL DEFEASANCE AND COVENANT DEFEASANCE 

Section 7.01 Option to Effect Legal Defeasance or Covenant Defeasance. 

The provisions in Article VIII of the Original Indenture shall not apply with respect to the Notes, and this Article 7 supersedes the
entirety thereof. The Company may at any time, at the option of its Board of Directors evidenced by a resolution set forth in an Officer’s Certificate, elect to have either Section 7.02 or 7.03 hereof be applied to all outstanding Notes
upon compliance with the conditions set forth below in this Article 7. 

  
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 Section 7.02 Legal Defeasance and Discharge. 

Upon the Company’s exercise under Section 7.01 hereof of the option applicable to this Section 7.02, the Company and each of the
Guarantors will, subject to the satisfaction of the conditions set forth in Section 7.04 hereof, be deemed to have been discharged from their obligations with respect to the Indenture and all outstanding Notes (including the Guarantees) on the
date the conditions set forth below are satisfied (hereinafter, “Legal Defeasance”). For this purpose, Legal Defeasance means that the Company and the Guarantors will be deemed to have paid and discharged the entire
Indebtedness represented by the outstanding Notes (including the Guarantees), which will thereafter be deemed to be “outstanding” only for the purposes of Section 7.05 hereof and the other Sections of this Supplemental Indenture
referred to in clauses (1) and (2) below, and to have satisfied all their other obligations under such Notes, the Guarantees and the Indenture (and the Trustee, on demand of and at the expense of the Company, shall execute proper instruments
acknowledging the same), except for the following provisions which will survive until otherwise terminated or discharged hereunder: 
 (1)
the rights of Holders of outstanding Notes to receive payments in respect of the principal of, premium on, if any, or interest on, such Notes when such payments are due from the trust referred to below; 

(2) the Company’s obligations with respect to the Notes concerning issuing temporary Notes, registration of Notes, mutilated, destroyed,
lost or stolen Notes and the maintenance of an office or agency for payment and money for security payments held in trust; 
 (3) the
rights, powers, trusts, duties and immunities of the Trustee under the Indenture, and the Company’s and the Guarantors’ obligations in connection therewith; and 

(4) this Article 7. 
 Following
the Company’s exercise of its Legal Defeasance option, payment of the Notes may not be accelerated because of an Event of Default. 

Subject to compliance with this Article 7, the Company may exercise its option under this Section 7.02 notwithstanding the prior exercise
of its option under Section 7.03 hereof. 
 Section 7.03 Covenant Defeasance. 

Upon the Company’s exercise under Section 7.01 hereof of the option applicable to this Section 7.03, the Company and each of the
Guarantors will, subject to the satisfaction of the conditions set forth in Section 7.04 hereof, be released from each of their obligations under the covenants contained in Article 4 hereof, clause (3) of Section 5.01(a) hereof and
Sections 4.3, 4.5, 4.6 and 4.7 of the Original Indenture, in each case with respect to the outstanding Notes, and the Guarantors will be deemed to have been discharged from their obligations with respect to all Guarantees on and after the date the
conditions set forth in Section 7.04 hereof are satisfied (hereinafter, “Covenant Defeasance”), and the Notes will thereafter be deemed not “outstanding” for the purposes of any direction, waiver, consent or
declaration or act of Holders (and the consequences of any thereof) in connection with such covenants, but will continue to be deemed “outstanding” for all other purposes hereunder (it being understood that such Notes will not be deemed
outstanding for accounting purposes). For this purpose, Covenant Defeasance means that, with respect to the outstanding Notes and Guarantees, the Company and the Guarantors may omit to comply with and will have no liability in respect of any term,
condition or limitation set forth in any such covenant, whether directly or indirectly, by reason of any reference elsewhere herein to any such covenant or by reason of any reference in any such covenant to any other provision herein or in any other


  
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document and such omission to comply will not constitute a Default or an Event of Default under Section 6.01 hereof, but, except as specified above, the remainder of the Indenture and such
Notes and Guarantees will be unaffected thereby. In addition, upon the Company’s exercise under Section 7.01 hereof of the option applicable to this Section 7.03, subject to the satisfaction of the conditions set forth in
Section 7.04 hereof, Sections 6.01 (3), (4), (5), (6) and (7) hereof will not constitute Events of Default. 
 Section 7.04 Conditions to
Legal or Covenant Defeasance. 
 In order to exercise either Legal Defeasance or Covenant Defeasance under either Section 7.02 or
7.03 hereof: 
 (1) the Company must irrevocably deposit with the Trustee, in trust, for the benefit of the Holders, cash in
U.S. dollars, non-callable Government Securities, or a combination thereof, in such amounts as will be sufficient, in the opinion of a nationally recognized investment bank, appraisal firm or firm of
independent public accountants, to pay the principal of, premium on, if any, and interest on, the outstanding Notes on the stated date for payment thereof or on the applicable redemption date, as the case may be, and the Company must specify whether
the Notes are being defeased to such stated date for payment or to a particular redemption date; 
 (2) in the case of Legal
Defeasance, the Company must deliver to the Trustee an Opinion of Counsel confirming that: 
 (A) the Company has received
from, or there has been published by, the Internal Revenue Service a ruling; or 
 (B) since the date of this Supplemental
Indenture, there has been a change in the applicable federal income tax law, 
 in either case to the effect that, and based thereon such
Opinion of Counsel shall confirm that, the beneficial owners of the outstanding Notes will not recognize income, gain or loss for federal income tax purposes as a result of such Legal Defeasance and will be subject to federal income tax on the same
amounts, in the same manner and at the same times as would have been the case if such Legal Defeasance had not occurred; 

(3) in the case of Covenant Defeasance, the Company must deliver to the Trustee an Opinion of Counsel confirming that the
beneficial owners of the outstanding Notes will not recognize income, gain or loss for federal income tax purposes as a result of such Covenant Defeasance and will be subject to federal income tax on the same amounts, in the same manner and at the
same times as would have been the case if such Covenant Defeasance had not occurred; 
 (4) no Default or Event of Default
shall have occurred and is continuing on the date of such deposit (other than a Default or Event of Default resulting from the borrowing of funds to be applied to such deposit (and any similar concurrent deposit relating to other Indebtedness), and
the granting of Liens to secure such borrowings); 
 (5) such Legal Defeasance or Covenant Defeasance will not result in a
breach or violation of, or constitute a default under, any material agreement or instrument (other than the Indenture and the agreements governing any other Indebtedness being defeased, discharged or replaced) to which the Company or any of the
Guarantors is a party or by which the Company or any of the Guarantors is bound (other than a Default or Event of Default resulting from the borrowing of funds to be applied to such deposit (and any similar concurrent deposit relating to other
Indebtedness) and the granting of Liens to secure such borrowings); 

  
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 (6) the Company must deliver to the Trustee an Officer’s Certificate
stating that the deposit was not made by the Company with the intent of preferring the Holders of Notes over the other creditors of the Company with the intent of defeating, hindering, delaying or defrauding any creditors of the Company or others;
and 
 (7) the Company must deliver to the Trustee an Officer’s Certificate and an Opinion of Counsel, each stating that
all conditions precedent relating to the Legal Defeasance or the Covenant Defeasance have been complied with. 
 Section 7.05 Deposited Money and
Government Securities to be Held in Trust; Other Miscellaneous Provisions. 
 Subject to Section 7.06, all money and non-callable Government Securities (including the proceeds thereof) deposited with the Trustee (or other qualifying trustee, collectively for purposes of this Section 7.05, the
“Trustee”) pursuant to Section 7.04 in respect of the outstanding Notes will be held in trust and applied by the Trustee, in accordance with the provisions of such Notes and the Indenture, to the payment, either directly
or through any Paying Agent (including the Company acting as Paying Agent) as the Trustee may determine, to the Holders of such Notes of all sums due and to become due thereon in respect of principal, premium, if any, and interest but such money
need not be segregated from other funds except to the extent required by law. 
 The Company will pay and indemnify the Trustee against any
tax, fee or other charge imposed on or assessed against the cash or non-callable Government Securities deposited pursuant to Section 7.04 or the principal and interest received in respect thereof other
than any such tax, fee or other charge which by law is for the account of the Holders of the outstanding Notes. 
 Notwithstanding anything
in this Article 7 to the contrary, the Trustee will deliver or pay to the Company from time to time upon the request of the Company any money or non-callable Government Securities held by it as provided in
Section 7.04 which, in the opinion of a nationally recognized firm of independent public accountants expressed in a written certification thereof delivered to the Trustee (which may be the opinion delivered under Section 7.04(1)), are in
excess of the amount thereof that would then be required to be deposited to effect an equivalent Legal Defeasance or Covenant Defeasance. 

Section 7.06 Repayment to Company. 

Subject to the requirements of applicable law, any monies deposited with or paid to the Trustee for payment of the principal of or interest on
the Notes and not applied but remaining unclaimed by the Holders of the Notes for two years after the date upon which the principal of or interest on such Notes, as the case may be, shall have become due and payable, shall be repaid to the Company
by the Trustee on demand, and all liability of the Trustee shall thereupon cease with respect to such monies; and the Holder of any of the Notes shall thereafter look only to the Company for any payment or delivery that such Holder of the Notes may
be entitled to collect unless an applicable abandoned property law designates another person. 

  
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 Section 7.07 Reinstatement. 

If the Trustee or Paying Agent is unable to apply any U.S. dollars or non-callable Government
Securities in accordance with Section 7.02 or 7.03, as the case may be, by reason of any order or judgment of any court or governmental authority enjoining, restraining or otherwise prohibiting such application, then the Company’s and the
Guarantors’ obligations under the Indenture and the Notes and the Guarantees will be revived and reinstated as though no deposit had occurred pursuant to Section 7.02 or 7.03 until such time as the Trustee or Paying Agent is permitted to
apply all such money in accordance with Section 7.02 or 7.03, as the case may be; provided, however, that, if the Company makes any payment of principal of, premium on, if any, or interest on, any Note following the reinstatement of its
obligations, the Company will be subrogated to the rights of the Holders of such Notes to receive such payment from the money held by the Trustee or Paying Agent. 

ARTICLE 8. 
 SATISFACTION
AND DISCHARGE 
 Section 8.01 Satisfaction and Discharge of the Supplemental Indenture.  

Articles VIII and XI of the Original Indenture shall not apply to the Notes. Instead, the satisfaction and discharge provisions set forth in
this Article 8 shall, with respect to the Notes, supersede in their entirety Articles VIII and XI of the Original Indenture, and all references in the Original Indenture to Articles VIII and XI thereof and satisfaction and discharge
provisions therein, as the case may be, shall, with respect to the Notes, be deemed to be references to this Article 9 and the satisfaction and discharge provisions set forth in this Article 8, respectively. 

The Indenture will be discharged with respect to the Notes and will cease to be of further effect as to all Notes issued hereunder, when: 

(1) either: 

(a) all Notes that have been authenticated, except lost, stolen or destroyed Notes that have been replaced or paid and Notes
for whose payment money has been deposited in trust and thereafter repaid to the Company, have been delivered to the Trustee for cancellation; or 

(b) all Notes that have not been delivered to the Trustee for cancellation have become due and payable by reason of the giving
of a notice of redemption or otherwise or will become due and payable within one year or are to be called for redemption within one year and the Company or any Guarantor has irrevocably deposited or caused to be deposited with the Trustee as trust
funds in trust solely for the benefit of the Holders, cash in U.S. dollars, non-callable Government Securities, or a combination thereof, in amounts as will be sufficient, in the opinion of a nationally
recognized investment bank, appraisal firm or firm of independent public accountants, without consideration of any reinvestment of interest, to pay and discharge the entire Indebtedness on the Notes not delivered to the Trustee for cancellation for
principal of, premium on, if any, and interest on, the Notes to the date of maturity or redemption; 
 (2) in respect of clause 1(b), no
Default or Event of Default has occurred and is continuing on the date of the deposit (other than a Default or Event of Default resulting from the borrowing of funds to be applied to such deposit and any similar deposit relating to other
Indebtedness and, in each case, the granting of Liens to secure such borrowings) and the deposit will not result in a breach or violation of, or constitute a default under, any other material instrument to which the Company or any Guarantor is a
party or by which the Company or any Guarantor is bound (other than with respect to the borrowing of funds to be applied concurrently to make the deposit required to effect such satisfaction and discharge and any similar concurrent deposit relating
to other Indebtedness, and in each case the granting of Liens to secure such borrowings); 

  
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 (3) the Company or any Guarantor has paid or caused to be paid all sums payable by it under
the Indenture with respect to the Notes; and 
 (4) the Company has delivered irrevocable instructions to the Trustee under the Indenture to
apply the deposited money toward the payment of the Notes at maturity or on the redemption date, as the case may be. 
 In addition, the
Company must deliver an Officer’s Certificate and an Opinion of Counsel to the Trustee stating that all conditions precedent to satisfaction and discharge have been satisfied. 

Notwithstanding the satisfaction and discharge of the Indenture, if money has been deposited with the Trustee pursuant to subclause
(b) of clause (1) of this Section 8.01, the provisions of Sections 8.02 and 7.06 will survive. In addition, nothing in this Section 8.01 will be deemed to discharge those provisions of Section 7.6 of the Original Indenture,
that, by their terms, survive the satisfaction and discharge of the Indenture. 
 Section 8.02 Application of Trust Money. 

Subject to the provisions of Section 7.06, all money deposited with the Trustee pursuant to Section 8.01 shall be held in trust and
applied by it, in accordance with the provisions of the Notes and the Indenture, to the payment, either directly or through any Paying Agent (including the Company acting as its own Paying Agent) as the Trustee may determine, to the Persons entitled
thereto, of the principal, premium, if any, and interest, for whose payment such money has been deposited with the Trustee; but such money need not be segregated from other funds except to the extent required by law. 

If the Trustee or Paying Agent is unable to apply any money or Government Securities in accordance with Section 8.01 by reason of any
legal proceeding or by reason of any order or judgment of any court or governmental authority enjoining, restraining or otherwise prohibiting such application, the Company’s and any Guarantor’s obligations under the Indenture and the Notes
shall be revived and reinstated as though no deposit had occurred pursuant to Section 8.01; provided that if the Company has made any payment of principal of, premium on, if any, or interest, on, any Notes because of the reinstatement of
its obligations, the Company shall be subrogated to the rights of the Holders of such Notes to receive such payment from the money or Government Securities held by the Trustee or Paying Agent. 

ARTICLE 9. 
 GUARANTEES

 Section 9.01 Guarantee. 

Subject to this Article 9, each of the Guarantors hereby, jointly and severally, unconditionally guarantees to each Holder of a Note
authenticated and delivered by the Trustee and to the Trustee and its successors and assigns, irrespective of the validity and enforceability of the Indenture, the Notes or the obligations of the Company hereunder or thereunder, that: 

(1) the principal of, premium on, if any, and interest, on, the Notes will be promptly paid in full when due, whether at
maturity, by acceleration, redemption or otherwise, and interest on the overdue principal of, premium on, if any, and interest, on, the Notes, if lawful, and all other obligations of the Company to the Holders or the Trustee hereunder or thereunder
will be promptly paid in full or performed, all in accordance with the terms hereof and thereof; and 

  
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 (2) in case of any extension of time of payment or renewal of any Notes or
any of such other obligations, that same will be promptly paid in full when due or performed in accordance with the terms of the extension or renewal, whether at Stated Maturity, by acceleration or otherwise. 

Failing payment when due of any amount so guaranteed or any performance so guaranteed for whatever reason, the Guarantors will be jointly and
severally obligated to pay the same immediately. Each Guarantor agrees that this is a guarantee of payment and not a guarantee of collection. 

(b) The Guarantors hereby agree that their obligations hereunder are unconditional, irrespective of the validity, regularity or enforceability
of the Notes or the Indenture, the absence of any action to enforce the same, any waiver or consent by any Holder of the Notes with respect to any provisions hereof or thereof, the recovery of any judgment against the Company, any action to enforce
the same or any other circumstance which might otherwise constitute a legal or equitable discharge or defense of a guarantor. Each Guarantor hereby waives diligence, presentment, demand of payment, filing of claims with a court in the event of
insolvency or bankruptcy of the Company, any right to require a proceeding first against the Company, protest, notice and all demands whatsoever and covenant that this Guarantee will not be discharged except by complete performance of the
Obligations contained in the Notes and the Indenture. 
 (c) If any Holder or the Trustee is required by any court or otherwise to return to
the Company, the Guarantors or any custodian, trustee, liquidator or other similar official acting in relation to either the Company or the Guarantors, any amount paid by either to the Trustee or such Holder, this Guarantee, to the extent
theretofore discharged, will be reinstated in full force and effect. 
 (d) Each Guarantor agrees that it will not be entitled to any right
of subrogation in relation to the Holders in respect of any obligations guaranteed hereby until payment in full of all obligations guaranteed hereby. Each Guarantor further agrees that, as between the Guarantors, on the one hand, and the Holders and
the Trustee, on the other hand, (1) the maturity of the obligations guaranteed hereby may be accelerated as provided in Article 6 for the purposes of such Guarantor’s Guarantee, notwithstanding any stay, injunction or other prohibition
preventing such acceleration in respect of the obligations guaranteed hereby, and (2) in the event of any declaration of acceleration of such obligations as provided in Article 6, such obligations (whether or not due and payable) will forthwith
become due and payable by the Guarantors for the purpose of such Guarantor’s Guarantee. The Guarantors will have the right to seek contribution from any non-paying Guarantor so long as the exercise of
such right does not impair the rights of the Holders under the Guarantee. 
 Section 9.02 [Reserved]. 

Section 9.03 Limitation on Guarantor Liability. 

Each Guarantor, and by its acceptance of Notes, each Holder, hereby confirms that it is the intention of all such parties that the Guarantee of
such Guarantor not constitute a fraudulent transfer or conveyance for purposes of Bankruptcy Law, the Uniform Fraudulent Conveyance Act, the Uniform Fraudulent Transfer Act or any similar federal or state law to the extent applicable to any
Guarantee. To effectuate the foregoing intention, the Trustee, the Holders and the Guarantors hereby irrevocably agree that the obligations of such Guarantor will be limited to the maximum amount that will, after giving effect to such maximum amount
and all other contingent and fixed liabilities of such Guarantor that are relevant under such laws, and after giving effect to any collections from, rights to receive contribution from or payments made by or on behalf of any other Guarantor in
respect of the obligations of such other Guarantor under this Article 9, result in the obligations of such Guarantor under its Guarantee not 

  
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constituting a fraudulent transfer or conveyance. Each Guarantor that makes a payment under its Guarantee will be entitled upon payment in full of all Guaranteed Obligations under the Indenture
to a contribution from each other Guarantor in an amount equal to such other Guarantor’s pro rata portion of such payment based on the respective net assets of all the Guarantors at the time of such payment, determined in accordance with GAAP.

 Section 9.04 Execution and Delivery. 

To evidence its Guarantee set forth in Section 9.01, each Guarantor hereby agrees that this Supplemental Indenture will be executed on
behalf of such Guarantor by one of its Officers. 
 Each Guarantor hereby agrees that its Guarantee set forth in Section 9.01 will
remain in full force and effect notwithstanding the absence of the endorsement of any notation of such Guarantee on the Notes. 
 If an
Officer whose signature is on this Supplemental Indenture no longer holds that office at the time the Trustee authenticates the Notes, the Guarantee will be valid nevertheless. 

The delivery of any Note by the Trustee, after the authentication thereof hereunder, will constitute due delivery of the Guarantee set forth
in this Supplemental Indenture on behalf of the Guarantors. 
 In the event that the Company or any of its Subsidiaries creates or acquires
any Domestic Subsidiary after the date of this Supplemental Indenture, if required by Section 4.06, the Company will cause such Domestic Subsidiary to comply with the provisions of Section 4.06 and this Article 9, to the extent applicable.

 Section 9.05 Guarantors May Consolidate, etc., on Certain Terms. 

Subject to Section 9.06, a Guarantor may not sell or otherwise dispose of all or substantially all of its assets to, or consolidate with
or merge with or into another Person other than the Company or another Guarantor, unless, immediately after giving effect to such transaction: 

(a) such Guarantor shall be the surviving Person or the surviving Person (if other than such Guarantor) (such Guarantor or such surviving
Person, as the case may be, the “Surviving Guarantor”) formed by such merger, consolidation or amalgamation shall expressly assume, by supplemental indenture in form reasonably satisfactory to the Trustee, executed and
delivered to the Trustee by such surviving Person, the due and punctual payment of the principal of, and premium, if any, and interest on, the Notes, according to their tenor, and the due and punctual performance and observance of all the covenants
and conditions of the Indenture to be performed by such Guarantor; 
 (b) the Company shall deliver, or cause to be delivered, to the Trustee
an officer’s certificate and an opinion of counsel, each stating that all conditions precedent provided for in the Indenture relating to such transaction or series of transactions have been satisfied; and 

(c) immediately before and after giving effect to such transaction or series of transactions on a pro forma basis, no Default or Event of
Default shall have occurred and be continuing. 
 The Surviving Guarantor shall succeed to, and be substituted for, and may exercise every
right and power of such Guarantor under the Indenture. 

  
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 Except as set forth in Articles 4 and 5, and notwithstanding the foregoing, any Guarantor
may (i) merge into or transfer all or part of its properties and assets to another Guarantor or the Company, (ii) merge with an Affiliate of the Company solely for the purpose of reincorporating or reorganizing the Guarantor in the United
States, any state thereof, the District of Columbia or any territory thereof or (iii) convert into a Person organized or existing under the laws of a jurisdiction in the United States. 

Section 9.06 Releases. 
 (a) The
Guarantee of a Guarantor will be automatically and unconditionally released and discharged: 
 (1) in connection with any sale or other
disposition of all or substantially all of the assets of that Guarantor, by way of merger, consolidation or otherwise, to a Person that is not (either before or after giving effect to such transaction) the Company or Subsidiary of the Company; 

(2) in connection with any sale or other disposition of Capital Stock of that Guarantor to a Person that is not (either before or after giving
effect to such transaction) the Company or a Subsidiary of the Company, if the Guarantor ceases to be a Subsidiary of the Company as a result of the sale or other disposition; 

(3) if that Guarantor becomes an Immaterial Subsidiary; 

(4) if that Guarantor ceases to be a guarantor or other obligor with respect to any Indebtedness under any Credit Facility; provided,
however, that if, at any time following such release, that Guarantor subsequently guarantees or otherwise becomes an obligor with respect to any Indebtedness of the Company under a Credit Facility, then that Guarantor will be required to
provide a Guarantee in accordance with Section 4.06; 
 (5) upon legal defeasance, covenant defeasance or satisfaction and discharge of
the Indenture as provided in Article 7 and Article 8; or 
 (6) on the Fall Away Date. 

(b) Any release and discharge pursuant to Section 9.06(a) shall occur automatically upon the consummation of any such transaction without
any further action required of the Company, the applicable Guarantor or the Trustee; provided that the Trustee shall be entitled to an Officer’s Certificate and an Opinion of Counsel, each stating that all conditions precedent provided
for in the Indenture relating to such transaction have been complied with. 
 (c) If, on any date following the date of this Supplemental
Indenture: 
 (1)the Notes are rated Investment Grade by both Rating Agencies; and 

(2)no Default or Event of Default shall have occurred and be continuing, 

then, beginning on that day (the “Fall Away Date”) and continuing at all times thereafter regardless of any subsequent changes in the
rating of the Notes, the Guarantees of each of the Guarantors will be automatically released and Section 4.06 shall cease to apply to the Notes. 

  
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 ARTICLE 10. 

SUPPLEMENTAL INDENTURES 

Section 10.01 Supplemental Indentures Without Consent of Holders. In lieu of Section 9.1 of the Original Indenture, the
Company, the Guarantors and the Trustee may amend or supplement the Indenture, the Notes or the Guarantees without notice to, or the consent of, any Holder of the Notes: 

(a) to cure any ambiguity, defect or inconsistency; 

(b) to provide for uncertificated Notes in addition to or in place of Physical Notes; 

(c) to provide for the assumption of the Company’s obligations to Holders of Notes in the case of a merger or consolidation or sale of all
or substantially all of the Company’s assets; 
 (d) to make any change that would provide any additional rights or benefits to the
holders of Notes or that does not adversely affect the legal rights under the Indenture of any Holder; 
 (e) to comply with requirements of
the SEC in order to effect or maintain the qualification of the Indenture under the Trust Indenture Act of 1939, as amended (the “TIA”); 

(f) to conform this Supplemental Indenture, the Notes or the Guarantees and the form or terms of the Notes to the “Description of
notes” section as set forth in the Offering Memorandum as determined in good faith by the Company; 
 (g) to provide for the issuance of
Additional Notes in accordance with the limitations set forth in the Indenture as of the date of the Indenture; 
 (h) to release a Guarantor
from its Guarantee pursuant to the terms of the Indenture when permitted or required pursuant to the terms of the Indenture; 
 (i) to secure
the Notes and the related Guarantees or add covenants for the benefit of the Holders or to surrender any right or power conferred upon the Company or any Guarantor; 

(j) to add additional Guarantees; 

(k) to evidence and provide for the acceptance and appointment under the Indenture of a successor Trustee pursuant to the requirements hereof;
or 
 (l) to make any amendment to the provisions of the Indenture relating to the transfer or legending of the Notes; provided,
however, that (i) compliance with this Supplemental Indenture as so amended would not result in Notes being transferred in violation of the Securities Act, or any applicable securities law and (ii) such amendment does not materially
and adversely affect the rights of Holders to transfer Notes. 
 The consent of the Holders is not necessary to approve the particular form
of any proposed amendment. It is sufficient if such consent approves the substance of the proposed amendment. 
 Section 10.02 Supplemental
Indentures With Consent of Holders. Subject to Section 10.01, the Indenture, the Notes or the Guarantees may be amended or supplemented with the consent of the Holders of at least a majority in aggregate principal amount of
the then outstanding Notes (including, without limitation, Additional Notes, if any) voting as a single class (including, without limitation, consents 

  
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 obtained in connection with a tender offer or exchange offer for, or purchase of, the Notes), and any
existing Default or Event of Default (other than a Default or Event of Default in the payment of the principal of, premium on, if any, or interest, on, the Notes, except a payment default resulting from an acceleration that has been rescinded) or
compliance with any provision of the Indenture or the Notes or the Guarantees may be waived with the consent of the Holders of a majority in aggregate principal amount of the then outstanding Notes (including, without limitation, Additional Notes,
if any) voting as a single class (including, without limitation, consents obtained in connection with a purchase of, or tender offer or exchange offer for, Notes). In lieu of Section 9.2 of the Original Indenture, which shall not apply with
respect to the Notes, without the consent of each Holder affected thereby, no amendment, supplement or waiver, including a waiver in relation to a past Event of Default, may: 

(a) reduce the principal amount of Notes whose Holders must consent to an amendment, supplement or waiver; 

(b) reduce the principal of or change the fixed maturity of any Note or alter or waive any of the provisions with respect to the redemption of
the Notes (for the avoidance of doubt, the provisions with respect to the redemption of the Notes referred to in this clause (b) do not include the offers to purchase Notes described in Section 4.04); 

(c) reduce the rate of or change the time for payment of interest on any Note; 

(d) waive a Default or Event of Default in the payment of principal of, premium on, if any, or interest, on, the Notes (except a rescission of
acceleration of the Notes by the Holders of at least a majority in aggregate principal amount of the then outstanding Notes and a waiver of the payment default that resulted from such acceleration); 

(e) make any Note payable in money other than that stated in the Notes; 

(f) make any change in the provisions of the Indenture relating to waivers of past Defaults; 

(g) amend the contractual right expressly set forth in the Indenture or Notes of Holders to receive payments of principal of, premium on, if
any, or interest, on, the Notes on or after the due dates therefor or to institute suit to enforce such payment; 
 (h) waive a redemption
payment with respect to any Note (other than a payment required by Section 4.04);  

(i) prior to the Fall Away Date, release any Guarantor that is a Significant Subsidiary (or any group of Guarantors that, taken together, as of
the latest audited consolidated financial statements for the Company would constitute a Significant Subsidiary) from any of its obligations under its Guarantee or the Indenture, except in accordance with the terms of the Indenture; or 

(j) make any change in the preceding amendment and waiver provisions. 

The consent of the Holders is not necessary under the Indenture to approve the particular form of any proposed amendment. It is sufficient if
such consent approves the substance of the proposed amendment. 
 Section 10.03 Notice of Amendment or Supplement. After an
amendment or supplement under this Article 10 or Article IX of the Original Indenture becomes effective, the Company shall deliver to the Holders a notice briefly describing such amendment or supplement. However, the failure to give such
notice to all the Holders, or any defect in the notice, shall not impair or affect the validity of the amendment or supplement. 

  
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 ARTICLE 11. 

MISCELLANEOUS 
 Section 11.01
Governing Law. THIS SUPPLEMENTAL INDENTURE, EACH OF THE NOTES, EACH OF THE GUARANTEES AND ANY CLAIM, CONTROVERSY OR DISPUTE ARISING UNDER OR RELATED TO THIS SUPPLEMENTAL INDENTURE, EACH OF THE NOTES AND EACH OF THE GUARANTEES,
SHALL BE GOVERNED BY, AND CONSTRUED IN ACCORDANCE WITH, THE LAWS OF THE STATE OF NEW YORK. EACH OF THE COMPANY, EACH GUARANTOR OF ANY SERIES OF SECURITIES, THE TRUSTEE AND EACH HOLDER BY ACCEPTING A SECURITY IRREVOCABLY WAIVES, TO THE FULLEST EXTENT
PERMITTED BY APPLICABLE LAW, ANY AND ALL RIGHT TO TRIAL BY JURY IN ANY LEGAL PROCEEDING ARISING OUT OF OR RELATING TO THIS INDENTURE OR THE TRANSACTIONS CONTEMPLATED THEREBY. 

Section 11.02 No Security Interest Created. Nothing in this Supplemental Indenture, in the Notes or in the Guarantees expressed or
implied, shall be construed to constitute a security interest under the Uniform Commercial Code or similar legislation, as now or hereafter enacted and in effect, in any jurisdiction. 

Section 11.03 Trust Indenture Act.  

This Supplemental Indenture will not be subject to, or governed by, the TIA. 

Section 11.04 Benefits of Supplemental Indenture. Nothing in this Supplemental Indenture, in the Notes or the Guarantees, express or
implied, shall give to any person (including any Registrar, any Paying Agent and their successors hereunder), other than the parties hereto, any benefit or any legal or equitable right, remedy or claim under this Supplemental Indenture. 

Section 11.05 Calculations. The Company shall be responsible for making all calculations called for under the Notes. These
calculations include, but are not limited to, determinations of accrued interest payable on the Notes. The Company shall make all these calculations in good faith and, absent manifest error, the Company’s calculations shall be final and binding
on Holders of Notes. The Company shall provide a schedule of its calculations to the Trustee and the Trustee is entitled to rely conclusively upon the accuracy of the Company’s calculations without independent verification. The Trustee will
forward the Company’s calculations to any Holder of Notes upon the request of that Holder at the sole cost and expense of the Company. 

Section 11.06 Effect of Headings and Table of Contents. The Article and Section headings herein and the Table of Contents are for
convenience only and shall not affect the construction hereof. 
 Section 11.07 Execution in Counterparts. This Supplemental
Indenture may be executed in any number of counterparts, each of which shall be an original, but such counterparts shall together constitute but one and the same instrument. The words “execution,” “signed,” “signature,”
“delivery,” and words of like import in or relating to this Supplemental Indenture or any document to be signed in connection with this Supplemental Indenture shall be deemed to include electronic signatures, deliveries or the keeping of
records in electronic form, each of which shall be of the same legal effect, validity or enforceability as a manually executed signature, physical delivery thereof or the use of a paper-based recordkeeping system, as the case may be, and the parties
hereto consent to conduct the transactions contemplated hereunder by electronic means. 

  
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 Section 11.08 Separability Clause. In case any provision in this Supplemental
Indenture, in any Note or coupon or in any Guarantee shall be invalid, illegal or unenforceable, the validity, legality and enforceability of the remaining provisions shall not in any way be affected or impaired thereby. 

Section 11.09 Ratification of Original Indenture. The Original Indenture, as supplemented by this Supplemental Indenture, is in all
respects ratified and confirmed, and this Supplemental Indenture shall be deemed part of the Original Indenture in the manner and to the extent herein and therein provided. For the avoidance of doubt, each of the Company, each of the Guarantors and
each Holder of the Notes, by its acceptance of such Notes, acknowledges and agrees that all of the rights, privileges, protections, immunities, indemnities and benefits afforded to the 

Trustee under the Original Indenture are deemed to be incorporated herein, and shall be enforceable by the Trustee hereunder, in each of its capacities
hereunder as if set forth herein in full. 
 Section 11.10 The Trustee. The recitals in this Supplemental Indenture are made by
the Company and the Guarantors only and not the Trustee, and all of the provisions contained in the Original Indenture in respect of the rights, privileges, immunities, powers and duties of the Trustee shall be applicable in respect of the Notes,
the Guarantees and of this Supplemental Indenture as fully and with like effect as set forth in full herein. 
 The Trustee accepts the
amendments of the Indenture effected by this Supplemental Indenture, but on the terms and conditions set forth in the Indenture, including the terms and provisions defining and limiting the liabilities and responsibilities of the Trustee. Without
limiting the generality of the foregoing, the Trustee shall not be responsible in any manner whatsoever for or with respect to any of the recitals or statements contained herein, all of which recitals or statements are made solely by the Company, or
for or with respect to (i) the validity or sufficiency of this Supplemental Indenture or any of the terms or provisions hereof, (ii) the proper authorization hereof by the Company by action or otherwise, (iii) the due execution hereof
by the Company or (iv) the consequences of any amendment herein provided for, and the Trustee makes no representation with respect to any such matters. 

Section 11.11 No Recourse Against Others. 

No director, officer, employee, incorporator or stockholder of the Company or any Guarantor, as such, shall have any liability for any
obligations of the Company or the Guarantors under the Notes, the Indenture, the Guarantees or any claim based on, in respect of, or by reason of, such obligations or their creation. Each Holder of Notes by accepting a Note waives and releases all
such liability. The waiver and release are part of the consideration for issuance of the Notes. 
 [Remainder of the page intentionally
left blank] 

  
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 IN WITNESS WHEREOF, the parties hereto have executed this Supplemental Indenture as of the
date first written above. 
  

			
	SYNEOS HEALTH, INC.
		
	By:	 	 /s/ Jason Meggs



 
			
	Name:	 	Jason Meggs
	Title:	 	Chief Financial Officer


 [Signature Page to Supplemental Indenture] 













					
	Syneos Health US, Inc.
	inVentiv Commercial Services, LLC
		
	By	 	 /s/ Jason Meggs

		 	Name:	 	Jason Meggs
		 	Title:	 	Chief Financial Officer
	
	Syneos Health Communications, Inc.
	inChord Holding Corporation
	inVentiv Health Consulting, Inc.
	Pharmaceutical Institute, LLC
	Addison Whitney LLC
	Chamberlain Communications Group LLC
	inVentiv Health Public Relations, LLC
	Allidura Communications, LLC
	Chandler Chicco Agency, L.L.C.
	Biosector 2 LLC
	Litmus Medical Marketing Services LLC
	Syneos Health Medical Communications, LLC
	Palio + Ignite, LLC
	Navicor Group, LLC
	The Selva Group, LLC
	Gerbig, Snell/Weisheimer Advertising, LLC
	Cadent Medical Communications, LLC
	Taylor Strategy Partners, LLC
		
	By	 	 /s/ Mohammad Ali

		 	Name:	 	Mohammad Ali
		 	Title:	 	Treasurer


 [Signature Page to Supplemental Indenture] 













					
	Kendle Americas Investment Inc.
	Kendle Americas Management Inc.
		
	By	 	 /s/ Jonathan Olefson

		 	Name:	 	Jonathan Olefson
		 	Title:	 	Director, General Counsel, and
		 		 	Corporate Secretary
	
	
	Syneos Health Holdings, Inc.
		
	By	 	 /s/ Jonathan Olefson

		 	Name:	 	Jonathan Olefson
		 	Title:	 	Director and Secretary
	
	inVentiv Health Clinical, LLC
	inVentiv Health Clinical Research Services, LLC
		
	By	 	 /s/ Jonathan Olefson

		 	Name:	 	Jonathan Olefson
		 	Title:	 	Manager
	
	inVentiv Health Clinical Lab, Inc.
		
	By	 	 /s/ Jonathan Olefson

		 	Name:	 	Jonathan Olefson
		 	Title:	 	Director and Secretary


 [Signature Page to Supplemental Indenture] 













			
	inVentiv Health Research & Insights, LLC
		
	By	 	 /s/ Sara Epstein

		 	Name: Sara Epstein
		 	Title: Vice President
	
	 inVentiv Health Clinical SRE, LLC

inVentiv Clinical, LLC
 Syneos Health Clinical, Inc.

		
	By	 	 /s/ Robert Parks

		 	Name: Robert Parks
		 	Title: Treasurer


 [Signature Page to Supplemental Indenture] 













					
	 Syneos Health, LLC

		
	By	 	 /s/ Sara Epstein

		 	Name:	 	 Sara Epstein

		 	Title:	 	 SVP, Associate General Counsel



 [Signature Page to Supplemental Indenture] 












 
			
	WELLS FARGO BANK, NATIONAL ASSOCIATION, as Trustee
		
	By:	 	 /s/ Patrick Giordano

		 	Name: Patrick Giordano
		 	Title:   Vice President














 SCHEDULE A 

GUARANTORS 
  

			
	Entity Name	  	Jurisdiction of Organization
	 Allidura Communications LLC
	  	Delaware
	 Chamberlain Communications Group LLC
	  	Delaware
	 inChord Holding Corporation
	  	Delaware
	 inVentiv Clinical, LLC
	  	Delaware
	 inVentiv Health Clinical, LLC
	  	Delaware
	 inVentiv Health Clinical Research Services, LLC
	  	Delaware
	 inVentiv Health Public Relations, LLC
	  	Delaware
	 inVentiv Health Clinical SRE, LLC
	  	Delaware
	 inVentiv Health Research & Insights, LLC
	  	Delaware
	 Syneos Health, LLC
	  	Delaware
	 Syneos Health Clinical, Inc.
	  	Delaware
	 Syneos Health Holdings, Inc.
	  	Delaware
	 Syneos Health US, Inc.
	  	Delaware
	 BioSector 2 LLC
	  	New York
	 Chandler Chicco Agency, L.L.C.
	  	New York
	 Litmus Medical Marketing Services LLC
	  	New York
	 inVentiv Commercial Services, LLC
	  	New Jersey
	 inVentiv Health Clinical Lab, Inc.
	  	New Jersey
	 Addison Whitney LLC
	  	North Carolina
	 inVentiv Health Consulting, Inc.
	  	North Carolina
	 Pharmaceutical Institute, LLC
	  	North Carolina
	 Cadent Medical Communications, LLC
	  	Ohio
	 Gerbig Snell/Weisheimer Advertising, LLC
	  	Ohio
	 Kendle Americas Investment Inc.
	  	Ohio
	 Kendle Americas Management Inc.
	  	Ohio
	 Navicor Group, LLC
	  	Ohio
	 Palio + Ignite, LLC
	  	Ohio
	 Syneos Health Communications, Inc.
	  	Ohio
	 Syneos Health Medical Communications, LLC
	  	Ohio
	 Taylor Strategy Partners, LLC
	  	Ohio
	 The Selva Group, LLC
	  	Ohio













 APPENDIX A 

PROVISIONS RELATING TO INITIAL NOTES 
 The
following procedures shall apply to the Notes. Capitalized terms used but not defined in this Appendix A shall have the meaning given to such terms in this Indenture to which this Appendix A is attached. 

1. Definitions  
 1.1
Definitions 
 For the purposes of this Appendix A and this Indenture as a whole, the following terms shall have the meanings
indicated below: 
 “Applicable Procedures” means, with respect to any transfer or exchange of or for beneficial interests
in any Global Note, the rules and procedures of the Depositary, Euroclear and Clearstream that apply to such transfer or exchange. 

“Clearstream” means Clearstream Banking, sociètè anonyme. 

“Definitive Note” means a certificated Initial Note (bearing the Restricted Securities Legend if the transfer of such Note is
restricted by applicable law) that does not include the Global Notes Legend. 
 “Depositary” means The Depository Trust
Company, its nominees and their respective successors. 
 “Euroclear” means Euroclear Bank S.A./N.V. 

“Global Notes Legend” means the legend set forth under that caption in Exhibit A to this Indenture. 

“QIB” means a “qualified institutional buyer” as defined in Rule 144A. 

“Regulation S” means Regulation S under the Securities Act. 

“Regulation S Notes” means all Initial Notes offered and sold outside the United States in reliance on Regulation S.

 “Restricted Period” means, with respect to any Notes, the period of 40 consecutive days beginning on and including the
later of (a) the day on which such Notes are first offered to persons other than distributors (as defined in Regulation S under the Securities Act) in reliance on Regulation S, notice of which day shall be promptly given by the Company to
the Trustee, and (b) the Issue Date with respect to such Notes. 
 “Restricted Securities Legend” means the legend set
forth in Section 2.3(e)(i) herein. 
 “Rule 144A” means Rule 144A under the Securities Act. 

“Rule 144A Notes” means all Initial Notes offered and sold to QIBs in reliance on Rule 144A. 

“Securities Custodian” means the custodian with respect to a Global Note (as appointed by the Depositary) or any successor
person thereto, who shall initially be the Trustee. 
 “Transfer Restricted Notes” means Definitive Notes and any other
Notes that bear or are required to bear the Restricted Securities Legend. 

  
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 1.2 Other Definitions 

 

					
	Term:	  	Defined in Section:	 
	“Agent Members”	  	 	2.1(c)	 
	“Global Note”	  	 	2.1(b)	 
	“Regulation S Global Note”	  	 	2.1(b)	 
	“Rule 144A Global Note”	  	 	2.1(b)	 

 2. The Notes 

2.1 Form and Dating 
 (a)
The Initial Notes issued on the date hereof shall be (i) offered and sold by the Company pursuant to the Purchase Agreement, dated November 18, 2020, by and among the Company, the Guarantors party thereto and J.P. Morgan Securities LLC, as
representative of the initial purchasers, and (ii) resold, initially only to (1) QIBs in reliance on Rule 144A and (2) Persons other than U.S. Persons (as defined in Regulation S) in reliance on Regulation S. Such Initial Notes
may thereafter be transferred to, among others, (A) QIBs and purchasers in reliance on Regulation S and (B) pursuant to an exemption from registration under the Securities Act provided by Rule 144 thereunder (if applicable) or (C) in
accordance with another exemption from the registration requirements of the Securities Act (and based upon an Opinion of Counsel acceptable to the Company if the Company so requests). Additional Notes offered after the date hereof may be offered and
sold by the Company from time to time pursuant to one or more purchase agreements in accordance with applicable law. 
 (b) Global
Notes. Rule 144A Notes shall be issued initially in the form of one or more permanent Global Notes in definitive, fully registered form (collectively, the “Rule 144A Global Note”) and Regulation S Notes
shall be issued initially in the form of one or more Global Notes (collectively, the “Regulation S Global Note”), in each case without interest coupons and bearing the Global Notes Legend and Restricted Securities Legend, which
shall be deposited on behalf of the purchasers of the Notes represented thereby with the Securities Custodian, and registered in the name of the Depositary or a nominee of the Depositary, duly executed by the Company and authenticated by the Trustee
as provided in this Indenture. Beneficial ownership interests in the Regulation S Global Note shall not be exchangeable for interests in the Rule 144A Global Note or any other Note without a Restricted Securities Legend until the
expiration of the Restricted Period. The Rule 144A Global Note and the Regulation S Global Note are each referred to herein as a “Global Note” and are collectively referred to herein as “Global Notes”. The
aggregate principal amount of the Global Notes may from time to time be increased or decreased by adjustments made on the records of the Trustee and the Depositary or its nominee and on the schedules thereto as hereinafter provided. 

(c) Book-Entry Provisions. This Section 2.1(c) shall apply only to a Global Note deposited with or on behalf of the Depositary.

 The Company shall execute and the Trustee shall, in accordance with this Section 2.1(c) and Section 2.2 and pursuant to an
Officer’s Certificate, authenticate and deliver initially one or more Global Notes that (i) shall be registered in the name of the Depositary for such Global Note or Global Notes or the nominee of such Depositary and (ii) shall be
delivered by the Trustee to such Depositary or pursuant to such Depositary’s instructions or held by the Trustee as Securities Custodian. 

Members of, or participants in, the Depositary (“Agent Members”) shall have no rights under this Indenture with respect to
any Global Note held on their behalf by the Depositary or by the Trustee as Securities Custodian or under such Global Note, and the Depositary may be treated by the Company, the Trustee and any agent of the Company or the Trustee as the absolute
owner of such Global Note for all purposes whatsoever. Notwithstanding the foregoing, nothing herein shall prevent the Company, the Trustee or any agent of the Company or the Trustee from giving effect to any written certification, proxy or other
authorization furnished by the Depositary or impair, as between the Depositary and its Agent Members, the operation of customary practices of such Depositary governing the exercise of the rights of a Holder of a beneficial interest in any Global
Note. 

  
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 (d) Definitive Notes. Except as provided in Section 2.3 or 2.4, owners of
beneficial interests in Global Notes shall not be entitled to receive physical delivery of certificated Notes. 
 2.2 Authentication.
The Trustee shall authenticate and deliver (a) on the Issue Date, an aggregate principal amount of $600,000,000 3.625% Senior Notes due 2029 and (b) subject to the terms of this Indenture, any Additional Notes for an original issuance
specified in the Officer’s Certificate pursuant to Section 2.13 of this Indenture. The Officer’s Certificate with respect to the Additional Notes shall specify the amount of the Notes to be authenticated and the date on which such
Notes are to be authenticated. 
 2.3 Transfer and Exchange. 

(a) Transfer and Exchange of Definitive Notes. When Definitive Notes are presented to the Registrar with a request: 

(i) to register the transfer of such Definitive Notes; or 

(ii) to exchange such Definitive Notes for an equal principal amount of Definitive Notes of other authorized denominations,

 the Registrar shall register the transfer or make the exchange as requested if its reasonable requirements for such transaction are met; provided,
however, that the Definitive Notes surrendered for transfer or exchange: 
 (1) shall be duly endorsed or accompanied
by a written instrument of transfer in form reasonably satisfactory to the Company and the Registrar, duly executed by the Holder thereof or its attorney duly authorized in writing; and 

(2) in the case of Transfer Restricted Notes, are accompanied by the following additional information and documents, as
applicable: 
 (A) if such Definitive Notes are being delivered to the Registrar by a Holder for registration in the name of
such Holder, without transfer, a certification from such Holder to that effect (in the form set forth on the reverse side of the Initial Note); or 

(B) if such Definitive Notes are being transferred to the Company, a certification to that effect (in the form set forth on the
reverse side of the Initial Note); or 
 (C) if such Definitive Notes are being transferred pursuant to an exemption from
registration under the Securities Act or in reliance upon an exemption from the registration requirements of the Securities Act, (x) a certification to that effect (in the form set forth on the reverse side of the Initial Note) and (y) if
the Company so requests, an opinion of counsel or other evidence reasonably satisfactory to it as to the compliance with the restrictions set forth in the legend set forth in Section 2.3(e)(i). 

(b) Restrictions on Transfer of a Definitive Note for a Beneficial Interest in a Global Note. A Definitive Note may not be exchanged for
a beneficial interest in a Global Note except upon satisfaction of the requirements set forth below. Upon receipt by the Trustee of a Definitive Note, duly endorsed or accompanied by a written instrument of transfer in form reasonably satisfactory
to the Company and the Registrar, together with: (i) certification (in the form set forth on the reverse side of the Initial Note) that such Definitive Note is being transferred (1) to the Company, (2) to the Registrar for
registration in the name of a Holder, without transfer, (3) pursuant to an effective registration statement under the Securities Act, (4) to a QIB in accordance with Rule 144A, (5) outside the United States in an offshore
transaction within the meaning of Regulation S and in compliance with Rule 904 under the Securities Act, (6) in accordance with another exemption from the registration requirements of the Securities Act (and based upon an opinion of counsel
acceptable to the Company if the Company so requests) or (7) pursuant to another available exemption from registration provided by Rule 144 under the Securities Act; and 

  
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 (ii) written instructions directing the Trustee to make, or to direct
the Securities Custodian to make, an adjustment on its books and records with respect to such Global Note to reflect an increase in the aggregate principal amount of the Notes represented by the Global Note, such instructions to contain information
regarding the Depositary account to be credited with such increase, 
 then the Trustee shall cancel such Definitive Note and cause, or direct the
Securities Custodian to cause, in accordance with the standing instructions and procedures existing between the Depositary and the Securities Custodian, the aggregate principal amount of Notes represented by the Global Note to be increased by the
aggregate principal amount of the Definitive Note to be exchanged and shall credit or cause to be credited to the account of the Person specified in such instructions a beneficial interest in the Global Note equal to the principal amount of the
Definitive Note so canceled. If no Global Notes are then outstanding and the Global Note has not been previously exchanged for certificated Notes pursuant to Section 2.4, the Company shall issue and the Trustee shall authenticate, upon written
order of the Company in the form of an Officer’s Certificate, a new Global Note in the appropriate principal amount. 
 (c) Transfer
and Exchange of Global Notes. (i) The transfer and exchange of Global Notes or beneficial interests therein shall be effected through the Depositary, in accordance with this Indenture (including applicable restrictions on transfer set forth
herein, if any) and the procedures of the Depositary therefor. A transferor of a beneficial interest in a Global Note shall deliver a written order given in accordance with the Depositary’s procedures containing information regarding the
participant account of the Depositary to be credited with a beneficial interest in such Global Note or another Global Note and such account shall be credited in accordance with such order with a beneficial interest in the applicable Global Note and
the account of the Person making the transfer shall be debited by an amount equal to the beneficial interest in the Global Note being transferred. Transfers by an owner of a beneficial interest in the Rule 144A Global Note to a transferee who takes
delivery of such interest through the Regulation S Global Note, whether before or after the expiration of the Restricted Period, shall be made only upon receipt by the Trustee of a certification in the form provided on the reverse of the Initial
Notes from the transferor to the effect that such transfer is being made in accordance with Regulation S or (if available) Rule 144 under the Securities Act and that, if such transfer is being made prior to the expiration of the Restricted Period,
the interest transferred shall be held immediately thereafter through Euroclear or Clearstream. 
 (ii) If the proposed
transfer is a transfer of a beneficial interest in one Global Note to a beneficial interest in another Global Note, the Registrar shall reflect on its books and records the date and an increase in the principal amount of the Global Note to which
such interest is being transferred in an amount equal to the principal amount of the interest to be so transferred, and the Registrar shall reflect on its books and records the date and a corresponding decrease in the principal amount of the Global
Note from which such interest is being transferred. 
 (iii) Notwithstanding any other provisions of this Appendix (other
than the provisions set forth in Section 2.4), a Global Note may not be transferred as a whole except by the Depositary to a nominee of the Depositary or by a nominee of the Depositary to the Depositary or another nominee of the Depositary or
by the Depositary or any such nominee to a successor Depositary or a nominee of such successor Depositary. 
 (d) Restrictions on Transfer
of Regulation S Global Note. (i) Prior to the expiration of the Restricted Period, interests in the Regulation S Global Note may only be held through Euroclear or Clearstream. During the Restricted Period, beneficial
ownership interests in the Regulation S Global Note may only be sold, pledged or transferred through Euroclear or Clearstream in accordance with the Applicable Procedures and only (1) to the Company, (2) so long as such note is eligible
for resale pursuant to Rule 144A, to a person whom the selling Holder reasonably believes is a QIB that purchases for its own account or for the account of a QIB to whom notice is given that the resale, pledge or transfer is being made in
reliance on Rule 144A, (3) in an offshore transaction in accordance with Regulation S, (4) pursuant to an exemption from registration under the Securities Act provided by Rule 144 (if applicable) under the Securities Act,
(5) in accordance with another exemption from the registration requirements of the Securities Act (and based upon an opinion of counsel acceptable to the Company if the Company so requests) or (6) pursuant to an effective registration
statement under the Securities Act, in each case 

  
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in accordance with any applicable securities laws of any state of the United States. Prior to the expiration of the Restricted Period, transfers by an owner of a beneficial interest in the
Regulation S Global Note to a transferee who takes delivery of such interest through the Rule 144A Global Note shall be made only in accordance with Applicable Procedures and upon receipt by the Trustee of a written certification from the transferor
of the beneficial interest in the form provided on the reverse of the Initial Note to the effect that such transfer is being made to a QIB within the meaning of Rule 144A in a transaction meeting the requirements of Rule 144A. Such written
certification shall no longer be required after the expiration of the Restricted Period. 
 (ii) Upon the expiration of the
Restricted Period, beneficial ownership interests in the Regulation S Global Note shall be transferable in accordance with applicable law and the other terms of this Indenture. 

(e) Legend  

(i) Except as permitted by the following paragraphs (ii), (iii) or (iv), each Note certificate evidencing the Global Notes and
the Definitive Notes (and all Notes issued in exchange therefor or in substitution thereof) shall bear a legend in substantially the following form (each defined term in the legend being defined as such for purposes of the legend only): 

“THIS SECURITY HAS NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), OR THE SECURITIES
LAWS OF ANY STATE OR OTHER JURISDICTION. NEITHER THIS SECURITY NOR ANY INTEREST OR PARTICIPATION HEREIN MAY BE REOFFERED, SOLD, ASSIGNED, TRANSFERRED, PLEDGED, ENCUMBERED OR OTHERWISE DISPOSED OF IN THE ABSENCE OF SUCH REGISTRATION OR UNLESS SUCH
TRANSACTION IS EXEMPT FROM, OR NOT SUBJECT TO, SUCH REGISTRATION. THE HOLDER OF THIS SECURITY, BY ITS ACCEPTANCE HEREOF, AGREES ON ITS OWN BEHALF AND ON BEHALF OF ANY INVESTOR ACCOUNT FOR WHICH IT HAS PURCHASED SECURITIES, TO OFFER, SELL OR
OTHERWISE TRANSFER SUCH SECURITY, PRIOR TO THE DATE (THE “RESALE RESTRICTION TERMINATION DATE”) THAT IS [IN THE CASE OF RULE 144A NOTES: SIX MONTHS AFTER THE LATER OF THE ORIGINAL ISSUE DATE HEREOF, THE ORIGINAL ISSUE DATE OF THE ISSUANCE
OF ANY ADDITIONAL NOTES AND THE LAST DATE ON WHICH THE ISSUER OR ANY AFFILIATE OF THE ISSUER WAS THE OWNER OF THIS SECURITY (OR ANY PREDECESSOR OF SUCH SECURITY),] [IN THE CASE OF REGULATION S NOTES: 40 DAYS AFTER THE LATER OF THE ORIGINAL ISSUE
DATE HEREOF, THE ORIGINAL ISSUE DATE OF THE ISSUANCE OF ANY ADDITIONAL NOTES AND THE DATE ON WHICH THIS SECURITY (OR ANY PREDECESSOR OF SUCH SECURITY) WAS FIRST OFFERED TO PERSONS OTHER THAN DISTRIBUTORS (AS DEFINED IN RULE 902 OF REGULATION S) IN
RELIANCE ON REGULATION S], ONLY (A) TO THE COMPANY OR ANY SUBSIDIARY THEREOF, (B) PURSUANT TO A REGISTRATION STATEMENT THAT HAS BEEN DECLARED EFFECTIVE UNDER THE SECURITIES ACT, (C) FOR SO LONG AS THE SECURITIES ARE ELIGIBLE FOR
RESALE PURSUANT TO RULE 144A UNDER THE SECURITIES ACT (“RULE 144A”), TO A PERSON IT REASONABLY BELIEVES IS A “QUALIFIED INSTITUTIONAL BUYER” AS DEFINED IN RULE 144A THAT PURCHASES FOR ITS OWN ACCOUNT OR FOR THE ACCOUNT OF A
QUALIFIED INSTITUTIONAL BUYER TO WHOM NOTICE IS GIVEN THAT THE TRANSFER IS BEING MADE IN RELIANCE ON RULE 144A, (D) PURSUANT TO OFFERS AND SALES TO NON-U.S. PERSONS THAT OCCUR OUTSIDE THE UNITED STATES
WITHIN THE MEANING OF REGULATION S UNDER THE SECURITIES ACT, (E) TO AN INSTITUTIONAL “ACCREDITED INVESTOR” WITHIN THE MEANING OF RULE 501(a)(1), (2), (3) OR (7) UNDER THE SECURITIES ACT THAT IS NOT A QUALIFIED INSTITUTIONAL BUYER
AND THAT IS PURCHASING FOR ITS OWN ACCOUNT OR FOR THE ACCOUNT OF ANOTHER INSTITUTIONAL ACCREDITED INVESTOR, IN EACH CASE IN A MINIMUM PRINCIPAL AMOUNT OF $250,000 OF SECURITIES OR (F) PURSUANT TO ANOTHER AVAILABLE EXEMPTION FROM THE
REGISTRATION REQUIREMENTS OF THE SECURITIES ACT, SUBJECT TO THE COMPANY’S AND THE TRUSTEE’S RIGHT PRIOR TO ANY SUCH OFFER, SALE OR TRANSFER PURSUANT TO CLAUSES (D), (E) OR (F) TO REQUIRE THE DELIVERY OF AN OPINION OF COUNSEL,
CERTIFICATION AND/ OR OTHER INFORMATION SATISFACTORY TO EACH OF THEM. THIS LEGEND WILL BE REMOVED UPON THE REQUEST OF THE HOLDER AFTER THE RESALE RESTRICTION TERMINATION DATE. [IN THE CASE OF REGULATION S NOTES: BY ITS ACQUISITION HEREOF, THE HOLDER
HEREOF REPRESENTS THAT IT IS NOT A U.S. PERSON NOR IS IT PURCHASING FOR THE ACCOUNT OF A U.S. PERSON AND IS ACQUIRING THIS SECURITY IN AN OFFSHORE TRANSACTION IN ACCORDANCE WITH REGULATION S UNDER THE SECURITIES ACT.] 

 

  
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 BY ITS ACQUISITION OF THIS SECURITY, THE HOLDER AND SUBSEQUENT TRANSFEREE THEREOF WILL BE
DEEMED TO HAVE REPRESENTED AND WARRANTED THAT EITHER (1) NO PORTION OF THE ASSETS USED BY SUCH HOLDER OR TRANSFEREE TO ACQUIRE OR HOLD THIS SECURITY CONSTITUTES THE ASSETS OF AN EMPLOYEE BENEFIT PLAN SUBJECT TO TITLE I OF THE U.S. EMPLOYEE
RETIREMENT INCOME SECURITY ACT OF 1974, AS AMENDED (“ERISA”), OF A PLAN, INDIVIDUAL RETIREMENT ACCOUNT OR OTHER ARRANGEMENT THAT IS SUBJECT TO SECTION 4975 OF THE U.S. INTERNAL REVENUE CODE OF 1986, AS AMENDED (THE “CODE”) OR
PROVISIONS UNDER ANY OTHER U.S. OR NON-U.S. FEDERAL, STATE, LOCAL OR OTHER LAWS OR REGULATIONS THAT ARE SIMILAR TO SUCH PROVISIONS OF ERISA OR THE CODE (“SIMILAR LAWS”), OR OF AN ENTITY WHOSE
UNDERLYING ASSETS ARE CONSIDERED TO INCLUDE “PLAN ASSETS” OF ANY SUCH PLAN, ACCOUNT OR ARRANGEMENT, OR (2) THE ACQUISITION, HOLDING AND DISPOSITION OF THIS SECURITY WILL NOT CONSTITUTE OR RESULT IN A
NON-EXEMPT PROHIBITED TRANSACTION UNDER SECTION 406 OF ERISA OR SECTION 4975 OF THE CODE OR A VIOLATION UNDER ANY APPLICABLE SIMILAR LAWS.” 

Each Definitive Note shall bear the following additional legend: 

“IN CONNECTION WITH ANY TRANSFER, THE HOLDER SHALL DELIVER TO THE REGISTRAR AND TRANSFER AGENT SUCH CERTIFICATES AND OTHER INFORMATION AS
SUCH TRANSFER AGENT MAY REASONABLY REQUIRE TO CONFIRM THAT THE TRANSFER COMPLIES WITH THE FOREGOING RESTRICTIONS.” 

(ii) Upon any sale or transfer of a Transfer Restricted Note that is a Definitive Note, the Registrar shall permit the Holder
thereof to exchange such Transfer Restricted Note for a Definitive Note that does not bear the legends set forth above and rescind any restriction on the transfer of such Transfer Restricted Note if the Holder certifies in writing to the Registrar
that its request for such exchange was made in reliance on Rule 144 (such certification to be in the form set forth on the reverse of the Initial Note). 

(iii) After a transfer of any Initial Notes during the period of the effectiveness of a Shelf Registration Statement with
respect to such Initial Note, all requirements pertaining to the Restricted Securities Legend on such Initial Notes shall cease to apply and the requirements that any such Initial Notes be issued in global form shall continue to apply. 

(iv) Upon a sale or transfer after the expiration of the Restricted Period of any Initial Note acquired pursuant to Regulation
S, all requirements that such Initial Note bear the Restricted Securities Legend shall cease to apply and the requirements requiring any such Initial Note be issued in global form shall continue to apply. 

(v) Any Additional Notes sold in a registered offering shall not be required to bear the Restricted Securities Legend. 

(f) Cancellation or Adjustment of Global Note. At such time as all beneficial interests in a Global Note have either been exchanged for
Definitive Notes, transferred, redeemed, repurchased or cancelled, such Global Note shall be returned by the Depositary to the Trustee for cancellation or retained and cancelled by the Trustee. At any time prior to such cancellation, if any
beneficial interest in a Global Note is exchanged for Definitive Notes, transferred in exchange for an interest in another Global Note, redeemed, repurchased or canceled, the principal amount of Notes represented by such Global Note shall be reduced
and an adjustment shall be made on the books and records of the Trustee (if it is then the Securities Custodian for such Global Note) with respect to such Global Note, by the Trustee or the Securities Custodian, to reflect such reduction. 

  
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 (g) Obligations with Respect to Transfers and Exchanges of Notes 

(i) To permit registrations of transfers and exchanges, the Company shall execute upon receipt of a written request from the
Company and the Trustee shall authenticate, Definitive Notes and Global Notes at the Registrar’s request. 
 (ii) No
service charge shall be made for any registration of transfer or exchange, but the Company may require payment of a sum sufficient to cover any transfer tax, assessments, or similar governmental charge payable in connection therewith. 

(iii) Prior to the due presentation for registration of transfer of any Note, the Company, the Trustee, the Paying Agent or the
Registrar may deem and treat the person in whose name a Note is registered as the absolute owner of such Note for the purpose of receiving payment of principal of, premium, if any, and interest on such Note and for all other purposes whatsoever,
whether or not such Note is overdue, and none of the Company, the Trustee, the Paying Agent or the Registrar shall be affected by notice to the contrary. 

(iv) All Notes issued upon any transfer or exchange pursuant to the terms of this Indenture shall evidence the same debt and
shall be entitled to the same benefits under this Indenture as the Notes surrendered upon such transfer or exchange. 
 (h) No Obligation
of the Trustee 
 (i) The Trustee shall have no responsibility or obligation to any beneficial owner of a Global Note, a
member of, or a participant in the Depositary or any other Person with respect to the accuracy of the records of the Depositary or its nominee or of any participant or member thereof, with respect to any ownership interest in the Notes or with
respect to the delivery to any participant, member, beneficial owner or other Person (other than the Depositary) of any notice (including any notice of redemption or repurchase) or the payment of any amount, under or with respect to such Notes. All
notices and communications to be given to the Holders and all payments to be made to Holders under the Notes shall be given or made only to the registered Holders (which shall be the Depositary or its nominee in the case of a Global Note). The
rights of beneficial owners in any Global Note shall be exercised only through the Depositary subject to the applicable rules and procedures of the Depositary. The Trustee may rely and shall be fully protected in relying upon information furnished
by the Depositary with respect to its members, participants and any beneficial owners. 
 (ii) The Trustee shall have no
obligation or duty to monitor, determine or inquire as to compliance with any restrictions on transfer imposed under this Indenture or under applicable law with respect to any transfer of any interest in any Note (including any transfers between or
among Depositary participants, members or beneficial owners in any Global Note) other than to require delivery of such certificates, opinions and other documentation or evidence as are expressly required by, and to do so if and when expressly
required by, the terms of this Indenture, and to examine the same to determine substantial compliance as to form with the express requirements hereof. 

2.4 Definitive Notes. 

(a) A Global Note deposited with the Depositary or with the Trustee as Securities Custodian pursuant to Section 2.1 shall be transferred
to the beneficial owners thereof in the form of Definitive Notes in an aggregate principal amount equal to the principal amount of such Global Note, in exchange for such Global Note, only if such transfer complies with Section 2.3 and
(i) the Depositary notifies the Company that it is unwilling or unable to continue as a Depositary for such Global Note or if at any time the Depositary ceases to be a “clearing agency” registered under the Exchange Act, and, in
either case, a successor depositary is not appointed by the Company within 120 days of such notice or after the Company becomes aware of such event, or (ii) an Event of Default has occurred and is continuing or (iii) the Company, in
its sole discretion, notifies the Trustee in writing that it elects to cause the issuance of certificated Notes under this Indenture. 

  
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 (b) Any Global Note that is transferable to the beneficial owners thereof pursuant to this
Section 2.4 shall be surrendered by the Depositary to the Trustee, to be so transferred, in whole or from time to time in part, without charge, and the Trustee shall authenticate and deliver, upon such transfer of each portion of such Global
Note, an equal aggregate principal amount of Definitive Notes of authorized denominations. Any portion of a Global Note transferred pursuant to this Section 2.4 shall be executed, authenticated and delivered only in denominations of $2,000 and
whole multiples of $1,000 thereof and registered in such names as the Depositary shall direct. Any certificated Initial Note in the form of a Definitive Note delivered in exchange for an interest in the Global Note shall, except as otherwise
provided by Section 2.3(e), bear the Restricted Securities Legend. 
 (c) Subject to the provisions of Section 2.4(b), the
registered Holder of a Global Note may grant proxies and otherwise authorize any Person, including Agent Members and Persons that may hold interests through Agent Members, to take any action which a Holder is entitled to take under this Indenture or
the Notes. 
 (d) In the event of the occurrence of any of the events specified in Section 2.4(a)(i), (ii) or (iii), the Company shall
promptly make available to the Trustee a reasonable supply of Definitive Notes in fully registered form without interest coupons. 

  
 I-8 













 EXHIBIT A 

[Face of Note] 
  

[Global Notes Legend] 
 [THIS NOTE IS A GLOBAL
NOTE WITHIN THE MEANING OF THE INDENTURE HEREINAFTER REFERRED TO AND IS REGISTERED IN THE NAME OF A DEPOSITORY OR A NOMINEE OF A DEPOSITORY. THIS NOTE IS EXCHANGEABLE FOR NOTES REGISTERED IN THE NAME OF A PERSON OTHER THAN THE DEPOSITORY OR ITS
NOMINEE ONLY IN THE LIMITED CIRCUMSTANCES DESCRIBED IN THE INDENTURE, AND NO TRANSFER OF THIS NOTE (OTHER THAN A TRANSFER OF THIS NOTE AS A WHOLE BY THE DEPOSITORY TO A NOMINEE OF THE DEPOSITORY OR BY A NOMINEE OF THE DEPOSITORY TO THE DEPOSITORY OR
ANOTHER NOMINEE OF THE DEPOSITORY) MAY BE REGISTERED EXCEPT IN LIMITED CIRCUMSTANCES. 
 UNLESS THIS NOTE IS PRESENTED BY AN AUTHORIZED REPRESENTATIVE OF
THE DEPOSITORY TRUST COMPANY, A NEW YORK CORPORATION (“DTC”), TO THE COMPANY OR ITS AGENT FOR REGISTRATION OF TRANSFER, EXCHANGE OR PAYMENT, AND ANY NOTE ISSUED IS REGISTERED IN THE NAME OF CEDE & CO. OR IN SUCH OTHER NAME AS IS
REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF DTC (AND ANY PAYMENT HEREON IS MADE TO CEDE & CO. OR TO SUCH OTHER ENTITY AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF DTC), ANY TRANSFER, PLEDGE OR OTHER USE HEREOF FOR VALUE OR OTHERWISE
BY OR TO ANY PERSON IS WRONGFUL INASMUCH AS THE REGISTERED OWNER HEREOF, CEDE & CO., HAS AN INTEREST HEREIN. ] 
 [Restricted
Securities Legend] 
 [THIS SECURITY HAS NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), OR THE
SECURITIES LAWS OF ANY STATE OR OTHER JURISDICTION. NEITHER THIS SECURITY NOR ANY INTEREST OR PARTICIPATION HEREIN MAY BE REOFFERED, SOLD, ASSIGNED, TRANSFERRED, PLEDGED, ENCUMBERED OR OTHERWISE DISPOSED OF IN THE ABSENCE OF SUCH REGISTRATION OR
UNLESS SUCH TRANSACTION IS EXEMPT FROM, OR NOT SUBJECT TO, SUCH REGISTRATION. THE HOLDER OF THIS SECURITY, BY ITS ACCEPTANCE HEREOF, AGREES ON ITS OWN BEHALF AND ON BEHALF OF ANY INVESTOR ACCOUNT FOR WHICH IT HAS PURCHASED SECURITIES, TO OFFER, SELL
OR OTHERWISE TRANSFER SUCH SECURITY, PRIOR TO THE DATE (THE “RESALE RESTRICTION TERMINATION DATE”) THAT IS [IN THE CASE OF RULE 144A NOTES: SIX MONTHS AFTER THE LATER OF THE ORIGINAL ISSUE DATE HEREOF, THE ORIGINAL ISSUE DATE OF THE
ISSUANCE OF ANY ADDITIONAL NOTES AND THE LAST DATE ON WHICH THE ISSUER OR ANY AFFILIATE OF THE ISSUER WAS THE OWNER OF THIS SECURITY (OR ANY PREDECESSOR OF SUCH SECURITY),] [IN THE CASE OF REGULATION S NOTES: 40 DAYS AFTER THE LATER OF THE ORIGINAL
ISSUE DATE HEREOF, THE ORIGINAL ISSUE DATE OF THE ISSUANCE OF ANY ADDITIONAL NOTES AND THE DATE ON WHICH THIS SECURITY (OR ANY PREDECESSOR OF SUCH SECURITY) WAS FIRST OFFERED TO PERSONS OTHER THAN DISTRIBUTORS (AS DEFINED IN RULE 902 OF 

  
 A-1 













 REGULATION S) IN RELIANCE ON REGULATION S], ONLY (A) TO THE COMPANY OR ANY SUBSIDIARY THEREOF,
(B) PURSUANT TO A REGISTRATION STATEMENT THAT HAS BEEN DECLARED EFFECTIVE UNDER THE SECURITIES ACT, (C) FOR SO LONG AS THE SECURITIES ARE ELIGIBLE FOR RESALE PURSUANT TO RULE 144A UNDER THE SECURITIES ACT (“RULE 144A”), TO A
PERSON IT REASONABLY BELIEVES IS A “QUALIFIED INSTITUTIONAL BUYER” AS DEFINED IN RULE 144A THAT PURCHASES FOR ITS OWN ACCOUNT OR FOR THE ACCOUNT OF A QUALIFIED INSTITUTIONAL BUYER TO WHOM NOTICE IS GIVEN THAT THE TRANSFER IS BEING MADE IN
RELIANCE ON RULE 144A, (D) PURSUANT TO OFFERS AND SALES TO NON-U.S. PERSONS THAT OCCUR OUTSIDE THE UNITED STATES WITHIN THE MEANING OF REGULATION S UNDER THE SECURITIES ACT, (E) TO AN INSTITUTIONAL
“ACCREDITED INVESTOR” WITHIN THE MEANING OF RULE 501(a)(1), (2), (3) OR (7) UNDER THE SECURITIES ACT THAT IS NOT A QUALIFIED INSTITUTIONAL BUYER AND THAT IS PURCHASING FOR ITS OWN ACCOUNT OR FOR THE ACCOUNT OF ANOTHER INSTITUTIONAL
ACCREDITED INVESTOR, IN EACH CASE IN A MINIMUM PRINCIPAL AMOUNT OF $250,000 OF SECURITIES OR (F) PURSUANT TO ANOTHER AVAILABLE EXEMPTION FROM THE REGISTRATION REQUIREMENTS OF THE SECURITIES ACT, SUBJECT TO THE COMPANY’S AND THE
TRUSTEE’S RIGHT PRIOR TO ANY SUCH OFFER, SALE OR TRANSFER PURSUANT TO CLAUSES (D), (E) OR (F) TO REQUIRE THE DELIVERY OF AN OPINION OF COUNSEL, CERTIFICATION AND/ OR OTHER INFORMATION SATISFACTORY TO EACH OF THEM. THIS LEGEND WILL BE
REMOVED UPON THE REQUEST OF THE HOLDER AFTER THE RESALE RESTRICTION TERMINATION DATE. [IN THE CASE OF REGULATION S NOTES: BY ITS ACQUISITION HEREOF, THE HOLDER HEREOF REPRESENTS THAT IT IS NOT A U.S. PERSON NOR IS IT PURCHASING FOR THE ACCOUNT OF A
U.S. PERSON AND IS ACQUIRING THIS SECURITY IN AN OFFSHORE TRANSACTION IN ACCORDANCE WITH REGULATION S UNDER THE SECURITIES ACT.] 
 BY ITS ACQUISITION OF
THIS SECURITY, THE HOLDER AND SUBSEQUENT TRANSFEREE THEREOF WILL BE DEEMED TO HAVE REPRESENTED AND WARRANTED THAT EITHER (1) NO PORTION OF THE ASSETS USED BY SUCH HOLDER OR TRANSFEREE TO ACQUIRE OR HOLD THIS SECURITY CONSTITUTES THE ASSETS OF
AN EMPLOYEE BENEFIT PLAN SUBJECT TO TITLE I OF THE U.S. EMPLOYEE RETIREMENT INCOME SECURITY ACT OF 1974, AS AMENDED (“ERISA”), OF A PLAN, INDIVIDUAL RETIREMENT ACCOUNT OR OTHER ARRANGEMENT THAT IS SUBJECT TO SECTION 4975 OF THE U.S.
INTERNAL REVENUE CODE OF 1986, AS AMENDED (THE “CODE”) OR PROVISIONS UNDER ANY OTHER U.S. OR NON-U.S. FEDERAL, STATE, LOCAL OR OTHER LAWS OR REGULATIONS THAT ARE SIMILAR TO SUCH PROVISIONS OF ERISA
OR THE CODE (“SIMILAR LAWS”), OR OF AN ENTITY WHOSE UNDERLYING ASSETS ARE CONSIDERED TO INCLUDE “PLAN ASSETS” OF ANY SUCH PLAN, ACCOUNT OR ARRANGEMENT, OR (2) THE ACQUISITION, HOLDING AND DISPOSITION OF THIS SECURITY WILL
NOT CONSTITUTE OR RESULT IN A NON-EXEMPT PROHIBITED TRANSACTION UNDER SECTION 406 OF ERISA OR SECTION 4975 OF THE CODE OR A VIOLATION UNDER ANY APPLICABLE SIMILAR LAWS.] 

  
 A-2 













 CUSIP/ISIN [144A: 87166BAA0 / US87166BAA08] [Reg S: U8077BAA1 / USU8077BAA18] 

3.625% Senior Notes due 2029 
  

					
	No. ___	  		  	$____________*

 SYNEOS HEALTH, INC. 

promises to pay to                  or registered
assigns, 
 the principal sum of __________________________________________________________ DOLLARS [(or such lesser principal amount as shall be reflected
in the books and records of the Trustee and Depository)] on January 15, 2029. 
 Interest Payment Dates: January 15 and July 15 

Regular Record Dates: January 1 and July 1 
 Dated:
_______________, 2020 
 IN WITNESS WHEREOF, SYNEOS HEALTH, INC. has caused this instrument to be signed manually or by facsimile by two of its duly
authorized Officers. 
 Date: _______________, 2020 
  

			
	SYNEOS HEALTH, INC.
		
	By:	 	  

		 	Name:
		 	Title:
		
	By:	 	  

		 	Name:
		 	Title:


 This is one of the Notes referred to 

in the within-mentioned Indenture: 
  

	
	WELLS FARGO BANK, NATIONAL ASSOCIATION,
	as Trustee
	
	By:                                     
                                       
	Authorized Signatory
	
	                                      
                                      


  
 A-3 













 [Back of Note] 

3.625% Senior Notes due 2029 

Capitalized terms used herein have the meanings assigned to them in the Indenture referred to below unless otherwise indicated. 

(1) INTEREST. Syneos Health, Inc., a Delaware corporation (the
“Company”), promises to pay or cause to be paid interest on the principal amount of this Note at 3.625% per annum from November 24, 2020 until, but excluding, maturity. The Company will pay interest, if any, semi-annually in
arrears on January 15 and July 15 of each year, or if any such day is not a Business Day, on the next succeeding Business Day (each, an “Interest Payment Date”); provided that the first Interest Payment Date will
be                    . Interest on the Notes will accrue from the most recent date to which interest has been paid or, if no interest has been paid,
from the date of issuance; provided that, if this Note is authenticated between a record date referred to on the face hereof and the next succeeding Interest Payment Date, interest shall accrue from such next succeeding Interest Payment Date;
provided, further, that the first Interest Payment Date shall be                     . The Company will pay interest (including post-petition
interest in any proceeding under any Bankruptcy Law) on overdue principal at the otherwise applicable interest rate on the Notes to the extent lawful; it will pay interest (including post-petition interest in any proceeding under any Bankruptcy Law)
on overdue installments of interest (without regard to any applicable grace period), at the same rate to the extent lawful. 

Interest will be computed on the basis of a 360-day year comprised of twelve 30-day months. If any interest payment date, the maturity date, any redemption date, or any earlier required repurchase date of a Note falls on a day that is not a business day, the required payment will be made on
the next succeeding business day and no interest on such payment will accrue in respect of the delay. 
 (2)
METHOD OF PAYMENT. The Company will pay interest on the Notes (except defaulted interest) to the Persons who are registered Holders of Notes at 5:00 p.m., New York City time, on the
January 1 or July 1 next preceding the Interest Payment Date, even if such Notes are canceled after such record date and on or before such Interest Payment Date, except as provided in Section 2.12 of the Original Indenture with
respect to defaulted interest. The Company shall pay the principal of and interest on any Global Note in immediately available funds to the Depository or its nominee, as the case may be, as the registered Holder of such Global Note. The Company,
through the Paying Agent, shall make all payments of principal, premium, if any, and interest, with respect to Physical Notes by wire transfer of immediately available funds to the accounts specified by the Holders of the Physical Notes or, if no
such account is specified, by mailing a check to each such Holder’s registered address. Such payment will be in such coin or currency of the United States of America as at the time of payment is legal tender for payment of public and private
debts. 
 (3) PAYING AGENT AND REGISTRAR.
Initially, Wells Fargo Bank, National Association, the Trustee under the Indenture, will act as Paying Agent and Registrar. The Company may change the Paying Agent or Registrar without prior notice to the Holders of the Notes. The Company or any of
its Subsidiaries may act as Paying Agent or Registrar. 
 (4) INDENTURE. The Company
issued the Notes under a base indenture dated November 24, 2020, between the Company and the Trustee (the “Original Indenture”), as supplemented by the First Supplemental Indenture dated as of November 24, 2020 (the
“First Supplemental Indenture” and the Original Indenture as supplemented by the First Supplemental 

  
 A-4 













 Indenture, the “Indenture”) among the Company, the Guarantors and the
Trustee. The terms of the Notes include those stated in the Indenture. The Notes are subject to all such terms, and Holders are referred to the Indenture for a statement of such terms. To the extent any provision of this Note conflicts with the
express provisions of the Indenture, the provisions of the Indenture shall govern and be controlling. The Notes are unsecured obligations of the Company. The Indenture does not limit the aggregate principal amount of Notes that may be issued
thereunder. 
 (5) OPTIONAL REDEMPTION. 

(a) At any time prior to July 15, 2023, the Company may on any one or more occasions redeem up to 40% of the aggregate
principal amount of Notes issued under the Supplemental Indenture (including any Additional Notes), upon not less than 10 nor more than 60 days’ notice, at a redemption price equal to 103.625% of the principal amount of the Notes redeemed, plus
accrued and unpaid interest, to, but not including, the date of redemption (subject to the rights of Holders of Notes on the relevant record date to receive interest on the relevant interest payment date), with the net cash proceeds of an Equity
Offering by the Company; provided that: 
 (A) at least 60% of the aggregate principal amount of Notes originally
issued under the Supplemental Indenture on the date of the Supplemental Indenture remains outstanding after each such redemption (excluding Notes held by the Company and its Subsidiaries), unless all such Notes are repurchased or redeemed
substantially concurrently; and 
 (B) the redemption occurs within 180 days of the date of the closing of such Equity
Offering. 
 (b) At any time prior to January 15, 2024, the Company may on any one or more occasions redeem all or a
part of the Notes, upon not less than 10 nor more than 60 days’ notice, at a redemption price equal to 100% of the principal amount of the Notes redeemed, plus the Applicable Premium as of, and accrued and unpaid interest, to, but not
including, the date of redemption, subject to the rights of Holders of Notes on the relevant record date to receive interest due on the relevant interest payment date. 

(c) Except pursuant to the preceding paragraphs, the Notes will not be redeemable at the Company’s option prior to
January 15, 2024. 
 (d) On or after January 15, 2024, the Company may on any one or more occasions redeem all or a
part of the Notes, upon not less than 10 nor more than 60 days’ notice, at the redemption prices (expressed as percentages of principal amount) set forth below, plus accrued and unpaid interest, on the Notes redeemed, to, but not including, the
applicable date of redemption, if redeemed during the twelve-month period beginning on January 15 of the years indicated below, subject to the rights of Holders of Notes on the relevant record date to receive interest on the relevant interest
payment date: 
  

					
	 Year
	  	Percentage	 
	 2024
	  	 	101.813	% 
	 2025
	  	 	100.906	% 
	 2026 and thereafter
	  	 	100.000	% 


  
 A-5 













 Unless the Company defaults in the payment of the redemption price, interest will cease to
accrue on the Notes or portions thereof called for redemption on the applicable redemption date. 
 (6)
MANDATORY REDEMPTION; OPEN MARKET PURCHASES. The Company is not required to make mandatory redemption or sinking fund payments with respect to the
Notes. The Company may at any time and from time to time acquire Notes by tender offer, open market purchases, negotiated transactions or otherwise. 

(7) CHANGE OF CONTROL. If a Change of Control
occurs and is accompanied by a Ratings Event (together, a “Change of Control Triggering Event”), each Holder of Notes will have the right to require the Company to repurchase all or any part (equal to $2,000 or an integral multiple
of $1,000 in excess thereof) of that Holder’s Notes pursuant to an offer by the Company (a “Change of Control Offer”) on the terms set forth in the Indenture. In the Change of Control Offer, the Company will offer a payment in
cash equal to 101% of the aggregate principal amount of Notes repurchased, plus accrued and unpaid interest, on the Notes repurchased to, but not including, the date of purchase (the “Change of Control Payment”), subject to the
rights of Holders of Notes on the relevant record date to receive interest due on the relevant interest payment date. Within thirty days following any Change of Control Triggering Event, the Company will deliver electronically in pdf format or mail
a notice to each Holder with a copy to the Trustee or otherwise in accordance with the procedures of the Depositary describing the transaction or transactions that constitute the Change of Control Triggering Event and offering to repurchase Notes on
the date specified in the notice, which date will be no earlier than 30 days and no later than 60 days from the date such notice is mailed or otherwise delivered (a “Change of Control Payment Date”), pursuant to the procedures
required by the Indenture and described in such notice. The Company will comply with the requirements of Rule 14e-1 under the Exchange Act and any other securities laws and regulations thereunder to the extent
those laws and regulations are applicable in connection with the repurchase of the Notes as a result of a Change of Control Offer. To the extent that the provisions of any securities laws or regulations conflict with the Change of Control Offer
provisions of the Indenture, the Company will comply with the applicable securities laws and regulations and will not be deemed to have breached its obligations under the Change of Control Offer provisions of the Indenture by virtue of such
compliance. 
 (8) NOTICE OF REDEMPTION. At least 10 days
but not more than 60 days before a redemption date, the Company will deliver electronically in pdf format or mail or cause to be mailed, by first class mail, a notice of redemption to each Holder whose Notes are to be redeemed at its registered
address, except that redemption notices may be mailed more than 60 days prior to a redemption date if the notice is issued in connection with a defeasance of the Notes or a satisfaction and discharge of the Indenture pursuant to Articles 7 or 8 of
the First Supplemental Indenture. Notes and portions of Notes selected will be in amounts of $2,000 or whole multiples of $1,000 in excess thereof; except that if all of the Notes of a Holder are to be redeemed or purchased, the entire outstanding
amount of Notes held by such Holder shall be redeemed or purchased. 
 (9) DENOMINATIONS,
TRANSFER, EXCHANGE. The Notes are in registered form in denominations of $2,000 and integral multiples of $1,000 in excess thereof. The transfer of Notes may be registered and Notes may be exchanged
as provided in the Indenture. The Registrar and the Trustee may require a Holder, among other things, to furnish appropriate endorsements and transfer documents and the Company may require a Holder to pay any taxes and fees required by law or
permitted by the Indenture. The Company need not exchange or register the transfer of any Note or portion of a Note selected for redemption, except for the unredeemed portion of any Note being redeemed in part. Also, the Company need not exchange or
register the transfer of any Notes for a period of 15 days before the provision of a notice of redemption of Notes to be redeemed or during the period between a record date and the next succeeding Interest Payment Date. 

  
 A-6 













 (10) PERSONS DEEMED
OWNERS. The registered Holder of a Note may be treated as the owner of it for all purposes. Only registered Holders have rights under the Indenture. 

(11) AMENDMENT, SUPPLEMENT AND WAIVER. The
provisions governing amendment, supplement and waiver of any provision of the Indenture, the Notes or the Guarantees are set forth in Article 10 of the First Supplemental Indenture. 

(12) DEFAULTS AND REMEDIES. The Defaults and Event of
Default relating to the Notes are set forth in Section 6.01 of the First Supplemental Indenture.  
 (13)
TRUSTEE DEALINGS WITH COMPANY. The Trustee, in its individual or any other capacity, may make loans to, accept deposits from, and perform services for the Company or
its Affiliates, and may otherwise deal with the Company or its Affiliates, as if it were not the Trustee. 
 (14)
NO RECOURSE AGAINST OTHERS. No director, officer, employee, incorporator or stockholder of the Company or any Guarantor, as such, will have any liability for any
obligations of the Company or the Guarantors under the Notes, the Indenture, the Guarantees or for any claim based on, in respect of, or by reason of, such obligations or their creation. Each Holder of Notes by accepting a Note waives and releases
all such liability. The waiver and release are part of the consideration for issuance of the Notes. 
 (15)
AUTHENTICATION. This Note will not be valid until authenticated by the manual signature of the Trustee or an authenticating agent. 

(16) ABBREVIATIONS. Customary abbreviations may be used in the name of a Holder or an
assignee, such as: TEN COM (= tenants in common), TEN ENT (= tenants by the entireties), JT TEN (= joint tenants with right of survivorship and not as tenants in common), CUST (= Custodian), and U/G/M/A (= Uniform Gifts to Minors Act). 

(17) CUSIP NUMBERS. Pursuant to a recommendation promulgated by the Committee on Uniform
Security Identification Procedures, the Company has caused CUSIP numbers to be printed on the Notes, and the Trustee may use CUSIP numbers in notices of redemption as a convenience to Holders. No representation is made as to the accuracy of such
numbers either as printed on the Notes or as contained in any notice of redemption, and reliance may be placed only on the other identification numbers placed thereon. 

(18) GOVERNING LAW. THE INDENTURE, EACH OF THE NOTES, EACH OF THE GUARANTEES AND ANY CLAIM, CONTROVERSY OR DISPUTE
ARISING UNDER OR RELATED TO THE INDENTURE, EACH OF THE NOTES AND EACH OF THE GUARANTEES SHALL BE GOVERNED BY, AND CONSTRUED IN ACCORDANCE WITH THE LAWS OF THE STATE OF NEW YORK. 

  
 A-7 













 ASSIGNMENT FORM 

To assign this Note, fill in the form below: 

(I) or (we) assign and transfer this Note to:
                                         
                                         
                                       

(Insert assignee’s legal name) 
  

 
 (Insert assignee’s soc. sec. or
tax I.D. no.) 
  
  

  
  

  
  

  
  

(Print or type assignee’s name, address and zip code) 

and irrevocably appoint
                                         
                                         
                                         
                      
 to transfer this Note on
the books of the Company. The agent may substitute another to act for him. 
 Date: _______________ 

 

	
	Your
Signature:                                       
                                 
	(Sign exactly as your name appears on the face of this Note)


 Signature Guarantee*: _________________________ 

 

	*	 Participant in a recognized Signature Guarantee Medallion Program (or other signature guarantor acceptable to
the Trustee). 



  
 A-8 













 CERTIFICATE TO BE DELIVERED UPON EXCHANGE OR REGISTRATION OF TRANSFER 

RESTRICTED SECURITIES 
 This certificate
relates to $_________ principal amount of Notes held in (check applicable space) ____ book-entry or _____ definitive form by the undersigned. 
 The
undersigned (check one box below): 
  

	☐	 has requested the Trustee by written order to deliver in exchange for its beneficial interest in the Global
Note held by the Depositary a Note or Notes in definitive, registered form of authorized denominations and an aggregate principal amount equal to its beneficial interest in such Global Note (or the portion thereof indicated above);



  

	☐	 has requested the Trustee by written order to exchange or register the transfer of a Note or Notes.



 In connection with any transfer of any of the Notes evidenced by this certificate by a Person who is not an affiliate of the Company
occurring prior to the expiration of the period referred to in the last sentence of Rule 144(b)(1)(i) under the Securities Act, the undersigned confirms that such Notes are being transferred in accordance with its terms: 

CHECK ONE BOX BELOW 
  

					
	 (1)
	  	☐	  	to the Company; or
			
	 (2)
	  	☐	  	to the Registrar for registration in the name of the Holder, without transfer; or
			
	 (3)
	  	☐	  	pursuant to an effective registration statement under the Securities Act of 1933; or
			
	 (4)
	  	☐	  	inside the United States to a “qualified institutional buyer” (as defined in Rule 144A under the Securities Act of 1933) that purchases for its own account or for the account of a qualified institutional buyer to
whom notice is given that such transfer is being made in reliance on Rule 144A, in each case pursuant to and in compliance with Rule 144A under the Securities Act of 1933; or
			
	 (5)
	  	☐	  	outside the United States in an offshore transaction within the meaning of Regulation S under the Securities Act in compliance with Rule 903 or Rule 904 under the Securities Act of 1933 and such Note shall be held
immediately after the transfer through Euroclear or Clearstream until the expiration of the Restricted Period (as defined in the Indenture); or
			
	 (6)
	  	☐	  	pursuant to the exemption provided by Rule 144 under the Securities Act of 1933; or
			
	 (7)
	  	☐	  	in accordance with another exemption from the registration requirements of the Securities Act of 1933 (and based upon an opinion of counsel acceptable to the Company, if the Company so requests).

 Unless one of the boxes is checked, the Trustee shall refuse to register any of the Notes evidenced by this
certificate in the name of any Person other than the registered Holder thereof; provided, however, that if box (5), (6) or (7) is checked, the Trustee may require, prior to registering any such transfer of the Notes, such
legal opinions, certifications and other information as the Company has reasonably requested to confirm that such transfer is being made pursuant to an 

  
 A-9 













 exemption from, or in a transaction not subject to, the registration requirements of the
Securities Act of 1933. 
  

			
		  	                                      
                      
		  	Your Signature
	Signature Guarantee:	  	
		
	Date: ___________________	  	                                      
                      
	 Signature must be guaranteed
 by a participant
in a
 recognized signature guaranty
 medallion program or
other
 signature guarantor acceptable
 to the Trustee
	  	 Signature of Signature
 Guarantee


  
  

TO BE COMPLETED BY PURCHASER IF (4) ABOVE IS CHECKED. 

The undersigned represents and warrants that it is purchasing this Note for its own account or an account with respect to which it exercises
sole investment discretion and that it and any such account is a “qualified institutional buyer” within the meaning of Rule 144A under the Securities Act of 1933, and is aware that the sale to it is being made in reliance on
Rule 144A and acknowledges that it has received such information regarding the Company and the Guarantors as the undersigned has requested pursuant to Rule 144A or has determined not to request such information and that it is aware that
the transferor is relying upon the undersigned’s foregoing representations in order to claim the exemption from registration provided by Rule 144A. 
  

			
	Dated: ___________________	  	                                      
                          
		  	 NOTICE: To be executed by

an executive officer



  
 A-10 













 OPTION OF HOLDER TO
ELECT PURCHASE 
 If you want to elect to have this Note purchased by the Company pursuant to
Section 4.04 of the First Supplemental Indenture, check the box below: 
 ☐  Section 4.04 

If you want to elect to have only part of the Note purchased by the Company pursuant to Section Section 4.04 of the Indenture, state the
amount you elect to have purchased: 
 $_______________ 

Date: _______________ 
  

	
	Your
Signature:                                       
                                 
	(Sign exactly as your name appears on the face of this Note)
	
	 Tax Identification
No.:                                        
                    
  



 Signature Guarantee*: _________________________ 

 

	*	 Participant in a recognized Signature Guarantee Medallion Program (or other signature guarantor acceptable to
the Trustee). 



  
 A-11 













 SCHEDULE A 

EXCHANGES OF INTERESTS IN THE GLOBAL NOTE*** 

The following exchanges of a part of this Global Note for an interest in another Global Note or for a Definitive Note, or exchanges of a part
of another Global Note or Definitive Note for an interest in this Global Note, have been made: 
  

									
	 Date of Exchange
	  	Amount of decrease
in Amount of this
Global Note	  	Amount of increase
in Principal
Amount of this
Global Note	  	Principal Amount
of this Global Note
following such
decrease (or
increase)	  	Signature of
authorized Trustee
or Note Custodian
	  

	*** This Schedule should be included only if the Note is issued in global form.


  
 A-12 













 EXHIBIT B 

[FORM OF SUPPLEMENTAL INDENTURE 

TO BE DELIVERED BY SUBSEQUENT GUARANTORS] 

SUPPLEMENTAL INDENTURE (this “Supplemental Indenture”), dated as of ________________, among
__________________ (the “Guaranteeing Subsidiary”), a subsidiary of Syneos Health, Inc. (or its permitted successor), a Delaware corporation (the “Company”), the Company, the other Guarantors (as defined in the
Indenture referred to herein) and Wells Fargo Bank, National Association, as trustee under the Indenture referred to below (the “Trustee”). 

W I T N E S S E T H 

WHEREAS, the Company has heretofore executed and delivered to the Trustee an indenture (the “Original Indenture”), dated as
of November 24, 2020 and a First Supplemental Indenture, dated as of November 24, 2020 (the “First Supplemental Indenture” and, together with the Original Indenture, the “Indenture”) providing for the
issuance of 3.625% Senior Notes due 2029 (the “Notes”); 
 WHEREAS, the Indenture provides that under certain circumstances
the Guaranteeing Subsidiary shall execute and deliver to the Trustee a supplemental indenture pursuant to which the Guaranteeing Subsidiary shall unconditionally guarantee all of the Company’s Obligations under the Notes and the Indenture on
the terms and conditions set forth herein (the “Guarantee”); and 
 WHEREAS, pursuant to Section 10.01 of the First
Supplemental Indenture, the Trustee is authorized to execute and deliver this Supplemental Indenture. 
 NOW, THEREFORE, in consideration of
the foregoing and for other good and valuable consideration, the receipt of which is hereby acknowledged, the Guaranteeing Subsidiary and the Trustee mutually covenant and agree for the equal and ratable benefit of the Holders of the Notes as
follows: 
 1. CAPITALIZED TERMS. Capitalized terms used herein without definition shall have the meanings
assigned to them in the Indenture. 
 2. AGREEMENT TO GUARANTEE. The Guaranteeing Subsidiary
hereby agrees to provide an unconditional Guarantee on the terms and subject to the conditions set forth in the First Supplemental Indenture including but not limited to Article 9 thereof. 

4. NO RECOURSE AGAINST OTHERS. No director, officer, employee, incorporator or
stockholder of the Company or any Guarantor, as such, will have any liability for any obligations of the Company or the Guarantors under the Notes, the Indenture, the Guarantees or for any claim based on, in respect of, or by reason of, such
obligations or their creation. Each Holder of Notes by accepting a Note waives and releases all such liability. The waiver and release are part of the consideration for issuance of the Notes. 

5. NEW YORK LAW TO GOVERN. THIS SUPPLEMENTAL INDENTURE AND ANY CLAIM, CONTROVERSY OR DISPUTE ARISING UNDER OR RELATED TO THIS SUPPLEMENTAL
INDENTURE SHALL BE GOVERNED BY, AND CONSTRUED IN ACCORDANCE WITH, THE LAWS OF THE STATE OF NEW YORK. 
 6. COUNTERPARTS. The
parties may sign any number of copies of this Supplemental Indenture. Each signed copy shall be an original, but all of them together represent the same agreement. 

  
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 7. EFFECT OF HEADINGS. The Section headings
herein are for convenience only and shall not affect the construction hereof. 
 8. THE TRUSTEE. The Trustee
shall not be responsible in any manner whatsoever for or in respect of the validity or sufficiency of this Supplemental Indenture or for or in respect of the recitals contained herein, all of which recitals are made solely by the Guaranteeing
Subsidiary and the Company. 

  
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 IN WITNESS WHEREOF, the parties hereto have caused this Supplemental Indenture to be duly
executed and attested, all as of the date first above written. 
 Dated: _______________, 

 

			
	SYNEOS HEALTH, INC.
		
	By:	 	  

		 	Name:
		 	Title:
	
	[GUARANTEEING SUBSIDIARY]
		
	By:	 	  

		 	Name:
		 	Title:
	
	 WELLS FARGO BANK, NATIONAL ASSOCIATION,

as Trustee

		
	By:	 	  

		 	Authorized Signatory



  
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