From: "Jessica L. Poppe" <Jessica.Poppe@tufts.edu>

To: Elizabeth Mendez/DC/USEPA/US@EPA
Date: 02/25/2011 07:44 AM Subject: Questions about atrazine

Hello, My name is Jessica Poppe, and I am a senior at Tuft s University. I am currently in a public health engineering class, doi ng a semester-long project on pregnant women's exposure to atrazine fr om drinking water. While looking through the Scientific Advisory Panel meetings for the Reevaluation of Human Health Effects of Atrazine, I came across your name. I was wondering if you might be willing to an swer a few questions by e-mail (or on the phone)about atrazine exposure for my project.

Thank you for your time,

Jessica Poppe jessica.poppe@tufts.edu
978-844-1511

From: "Jessica L. Poppe" [Jessica.Poppe@tufts.edu] Sent: 02/28/2011 03:50 PM EST To: Anna Lowit Subject: Re: Questions about atrazine

Dear Anna,

Thank you so much for looking at my questions! I'm not sure whether you will be able to answer them, but I would love to he ar your opinion on the reevaluation of atrazine and its health effects on humans, particularly pregnant women.

The assignment for my project was to select an envi ronmental hazard in a discrete setting with a specific population, and I decided to investigate atrazine in drinking water and the pote ntial effects on pregnant women. The first part of the project (alre ady completed) was to write a hazard narrative and give an overview of the hazard. Now, I am working on writing a risk assessment and vulnera bility assessment for atrazine. This part of the project focuses on t he professional and scientific knowledge about the severity of the haza rd and what makes the particular population vulnerable to the hazard. Later in the semester, we will analyze the risk management metho ds in place to control the hazard (existing policies, health educa tion, controls at the source, along the path, and at the personal lev el).

My Questions:

At what stage in the process is the reevaluation of atrazine at currently?

Where there any studies or research in particular t hat prompted the reevaluation or are playing a particularly importan t role in the reevaluation?

Does the EPA have an approximation for the number o f people exposed to concentrations of atrazine (maybe the population wi thin the 1,172 watersheds with potential vulnerability)?

What groups do you think are most vulnerable to the health effects ofatrazine?

Is there any current information on the mechanism o f how atrazine might specifically affect pregnant women? Since atrazine seems to affect the hypothalamic pituitary axis, is it know what affect these changes could
have on a fetus?

Are there any pre-existing health conditions that a re known to possibly intensify the health effects of atrazine on any pop ulation?

Has atrazine caused any major potential health effe cts outside of the reproductive or endocrine systems?

Thank you so much for your help. It would be really helpful to me if you could e-mail me back for any of the questions y ou are able to answer. Since I am in class for most of the day dur ing the week, I'm a little harder to reach by phone (978-844-1511), but I should be available for most of the day on Thursday and Frida y.

Thank you again, Jessica

Quoting Lowit.Anna@epamail.epa.gov:

> I'd be glad to talk to you. Can you first send m e written questions > and a description of your project?

>
> Anna

>

> > ----- Original Message ----- > From: "Jessica L. Poppe" [Jessica.Poppe@tufts.edu ] > Sent: 02/25/2011 07:45 AM EST > To: Anna Lowit > Subject: Questions about atrazine

>

>

> > Hello, > My name is Jessica Poppe, and I am a senior at Tu fts University. I am > currently in a public health engineering class, d oing a semester-long > project on pregnant women's exposure to atrazine from drinking water. > While looking through the Scientific Advisory Pan el meetings for the > Reevaluation of Human Health Effects of Atrazine, I came across your > name. I was wondering if you might be willing to answer a few > questions by e-mail (or on the phone)about atrazi ne exposure for my > project.

> > Thank you for your time,

> > Jessica Poppe > jessica.poppe@tufts.edu
> 978-844-1511

To: Nelson Thurman/DC/USEPA/US@EPA From: "Jessica L. Poppe" <Jessica.Poppe@tufts.edu> Date: 02/25/2011 07:47AM Subject: Questions about atrazine

### Hello,

My name is Jessica Poppe, and I am a senior at Tuft s University. I am currently in a public health engineering class, doi ng a semester-long project on pregnant women's exposure to atrazine fr om drinking water. While looking through the Scientific Advisory Panel meetings for the Reevaluation of Human Health Effects of Atrazine, I came across your name. I was wondering if you might be willing to an swer a few questions by e-mail (or on the phone)about atrazine exposure for my project.

Thank you for your time,

Jessica Poppe jessica.poppe@tufts.edu

978-844-1511