Exhibit
10.4


 


EXECUTION VERSION


 


FIRST AMENDMENT,
dated as of January 24, 2018 (this “Agreement”), to the Credit Agreement dated as of August 15, 2017 (as amended,
restated, amended and restated, supplemented, or otherwise modified from time to time, the “Credit Agreement”),
among EQT Avatar Holdings, Inc., a Delaware corporation, Certara Holdco, Inc., a Delaware corporation (the “Parent Borrower”),
Certara USA, Inc., a Delaware corporation (the “Co-Borrower” and, together with the Parent Borrower, the “Borrowers”),
EQT Avatar Intermediate, Inc., a Delaware corporation (“Holdings”), the financial institutions from time to
time party thereto, Jefferies Finance LLC (“Jefferies”), as Administrative Agent (in such capacity, the “Administrative
Agent”), and Jefferies and Golub Capital LLC, as Issuing Banks.


 


A.      
Pursuant to Section 2.22(a) of the Credit Agreement, the Borrowers have requested that the Person set forth on Schedule
I hereto (the “Incremental Term Loan Lender”) extend additional senior secured first lien incremental term
loans to the Parent Borrower under the Credit Agreement in an aggregate principal amount equal to $25,000,000 (the “Incremental
Term Loans”).


 


B.       
The Incremental Term Loan Lender is willing to provide the Incremental Term Loans to the Borrowers on the First Amendment
Closing Date (as defined in Section 6 hereof) on the terms set forth herein and in the Credit Agreement and subject to the conditions
set forth herein.


 


C.       
The Incremental Term Loans shall have the same terms (other than with respect to issue price) as, and become part
of the same Class of Term Loans as, the Initial Term Loans outstanding under the Credit Agreement immediately prior to the effectiveness
of this Agreement.


 


D.      
The proceeds of the Incremental Term Loans will be used, together with cash on hand of the Parent Borrower, (a) for
general corporate purposes, including the funding of one or more acquisitions and (b) to pay related fees and expenses incurred
in connection herewith and therewith. Accordingly, in consideration of the mutual agreements herein contained and other good and
valuable consideration, the sufficiency and receipt of which are hereby acknowledged, the parties hereto agree as follows:


 


SECTION
1. Definitions. Capitalized terms used but not defined in this Agreement have the meanings assigned thereto in the
Credit Agreement. The provisions of Section 1.03 of the Credit Agreement are hereby incorporated by reference herein, mutatis
mutandis. This Agreement shall be an “Incremental Facility Agreement” for all purposes of the Credit Agreement,
and shall be a “Loan Document” for all purposes of the Credit Agreement and the other Loan Documents. The Incremental
Term Loan Lender shall, upon the effectiveness of this Agreement in accordance with Section 6 hereof, be a party to the Credit
Agreement, have the rights and obligations of a Lender thereunder, and shall be a “Lender” for all purposes of the
Credit Agreement and the other Loan Documents.


 






     


     


    

 


SECTION
2. Incremental Term Loans.


 


(a) Incremental
Term Loans. On the terms and subject to the conditions set forth herein, the Incremental Term Loan Lender hereby agrees to
make Incremental Term Loans to the Borrowers on the First Amendment Closing Date in an aggregate principal amount set forth opposite
its name under the heading “Incremental Term Commitment” on Schedule I hereto (each, an “Incremental
Term Commitment” and collectively, the “Incremental Term Commitments”). It is understood and agreed
that, once funded, the Incremental Term Loans shall be added to (and form part of) each Term Borrowing of outstanding Term Loans
on a pro rata basis (based on the relative sizes of the various outstanding Borrowings), so that each Term Lender will participate
proportionately in each then outstanding Term Borrowing. Interest will begin accruing on the Incremental Term Loans on the First
Amendment Closing Date. Unless previously terminated, the Incremental Term Commitments shall terminate at 5:00 p.m., New York City
time, on the First Amendment Closing Date. Amounts borrowed under this Section 2(a) and repaid or prepaid may not be reborrowed.


 


(b) The Incremental
Term Loans shall be an “Incremental Facility” for all purposes of the Credit Agreement and the other Loan Documents.
The Incremental Term Loans shall have the same terms applicable to, and shall constitute, “Loans”, “Initial Term
Loans”, “Term Loans” and “Additional Term Loans” under the Credit Agreement. From and after the First
Amendment Closing Date, the Incremental Term Loan Lender shall constitute an “Initial Term Lender”, a “Term Lender”,
an “Additional Lender” and a “Lender” for all purposes of the Credit Agreement and the other Loan Documents.


 


SECTION
3. Amendments to the Credit Agreement. Subject to the satisfaction or waiver of the conditions set forth in Section
6 hereof, the Credit Agreement is hereby amended as follows:


 


(a) Section 1.01 of
the Credit Agreement is hereby amended by inserting the following definitions in the appropriate alphabetical order therein:


 


“First
Amendment” means the First Amendment, dated as of January 24, 2018, among the Borrowers, Holdings, the Guarantors party
thereto, the Administrative Agent and the Lenders party thereto.


 


“First
Amendment Closing Date” has the meaning assigned to such term in the First Amendment.


 


“First
Amendment Incremental Term Lender” has the meaning assigned to the term “Incremental Term Loan Lender” in
the First Amendment.


 


“First
Amendment Incremental Term Loans” has the meaning assigned to the term “Incremental Term Loans” in the First
Amendment.


 


(b) Section
1.01 of the Credit Agreement is hereby amended by amending and restating the definition of “Initial Term Loans” in
its entirety to read as follows:


 






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“Initial
Term Loans”: means (i) prior to the First Amendment Closing Date, the term loans made by the Initial Term Lenders to
the Initial Borrower pursuant to Section 2.01(a)(i) on the Closing Date and (ii) on and after the First Amendment Closing
Date, the collective reference to (a) the term loans made by the Initial Term Lenders to the Initial Borrower pursuant to Section
2.01(a)(i) on the Closing Date and (b) the First Amendment Incremental Term Loans made on the First Amendment Closing Date.


 


(c) Section 1.01 of
the Credit Agreement is hereby amended by inserting “the First Amendment,” after “this Agreement,” in the
definition of “Loan Documents”.


 


(d) Section 2.01(a)(i)
of the Credit Agreement is hereby amended by inserting “or, in the case of the First Amendment Incremental Term Loans, on
the First Amendment Closing Date” after “Closing Date” in such subclause (a)(i).


 


(e) Section 2.09(a)(i)
of the Credit Agreement is hereby amended by inserting “or, in the case of the First Amendment Incremental Term Loans, on
the First Amendment Closing Date” after “Closing Date” in each instance where such term appears in such subclause
(a)(i).


 


(f) Section 2.10(a)(i)
of the Credit Agreement is hereby replaced in its entirety as follows: 


 


“(a)(i)
The Parent Borrower hereby unconditionally promises to repay the outstanding principal amount of the Term Loans to the Administrative
Agent for the account of each Term Lender (A) commencing March 2018, on the last Business Day of each December, March, June and
September prior to the Initial Term Loan Maturity Date (each such date being referred to as a “Loan Installment Date”),
in each case in the amounts set forth in the table below (as such payments may be reduced from time to time as a result of the
application of prepayments in accordance with Section 2.11 and purchases or assignments in accordance with Section 9.05(g)
or increased as a result of any increase in the amount of such Term Loans pursuant to Section 2.22(a)), and (B) on
the Initial Term Loan Maturity Date, in an amount equal to the remainder of the principal amount of the Initial Term Loans outstanding
on such date, together in each case with accrued and unpaid interest on the principal amount to be paid to but excluding the date
of such payment.


 






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	Installment	Principal Amount
	March 31, 2018	$687,656.64
	June 30, 2018	$687,656.64
	September 30, 2018	$687,656.64
	December 31, 2018	$687,656.64
	March 31, 2019	$687,656.64
	June 30, 2019	$687,656.64
	September 30, 2019	$687,656.64
	December 31, 2019	$687,656.64
	March 31, 2020	$687,656.64
	June 30, 2020	$687,656.64
	September 30, 2020	$687,656.64
	December 31, 2020	$687,656.64
	March 31, 2021	$687,656.64
	June 30, 2021	$687,656.64
	September 30, 2021	$687,656.64
	December 31, 2021	$687,656.64
	March 31, 2022	$687,656.64
	June 30, 2022	$687,656.64
	September 30, 2022	$687,656.64
	December 31, 2022	$687,656.64
	March 31, 2023	$687,656.64
	June 30, 2023	$687,656.64
	September 30, 2023	$687,656.64
	December 31, 2023	$687,656.64
	March 31, 2024	$687,656.64
	June 30, 2024	$687,656.64


 


(g) Section 3.19 of
the Credit Agreement is hereby replaced in its entirety as follows:


 


“3.19
Use of Proceeds. The Borrowers shall use the proceeds of (a) the Initial Term Loans incurred on the Closing Date to finance
the Transactions (including to pay Transaction Costs), (b) the Revolving Loans incurred on the Closing Date to pay a portion of
the Transaction Costs and on and after the Closing Date for working capital and general corporate purposes (including any purpose
not prohibited by this Agreement), (c) the First Amendment Incremental Term Loans incurred on the First Amendment Closing Date,
together with cash on hand of the Borrowers, (i) for general corporate purposes, including the funding of one or more acquisitions
and (ii) to pay related fees and expenses incurred in connection therewith and with the First Amendment, and (d) any Incremental
Facility for working capital and other general corporate purposes, including the financing of Permitted Acquisitions, other Investments
and any other use not prohibited by this Agreement.”


 


(h) Section 5.11 of
the Credit Agreement is hereby amended by adding the following clause (e) to the end of such Section 5.11:


 


“(e)
The Borrowers shall use the proceeds of the First Amendment Incremental Term Loans incurred on the First Amendment Closing Date,
together with cash on hand of the Borrowers, (i) for general corporate purposes, including the funding of one or more acquisitions
and (ii) to pay related fees and expenses incurred in connection therewith and with the First Amendment.


 






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SECTION
4. Other Agreements. The Borrowers acknowledge and agree that as of the First Amendment Closing Date, the aggregate
principal amount of all Incremental Facilities and/or Incremental Equivalent Debt incurred or issued in reliance on the Incremental
Amount is $0.


 


SECTION
5. Representations and Warranties. To induce the other parties hereto to enter into this Agreement, Holdings and
the Borrowers hereby jointly and severally represent and warrant to the Administrative Agent and each Lender that, as of the First
Amendment Closing Date:


 


(a) Holdings
and each Borrower have the organizational power and authority, and the legal right, to enter into this Agreement and to carry out
the transactions contemplated by, and perform its obligations under, this Agreement, the Credit Agreement and the other Loan Documents;


 


(b) Holdings
and each Borrower have taken all necessary organizational action to authorize the execution, delivery and performance of this Agreement;


 


(c) This Agreement
has been duly executed and delivered on behalf of Holdings and each Borrower and constitutes the legal, valid and binding obligation
of Holdings and each Borrower, enforceable against Holdings and each Borrower in accordance with its terms, except as enforceability
may be limited by any applicable bankruptcy, insolvency, reorganization, moratorium or similar laws affecting the enforcement of
creditor’s rights generally, by general equitable principles (whether enforcement is sought by proceedings in equity or at
law) and by general principles of good faith and fair dealing; and


 


(d) Each of
the representations and warranties made by any Loan Party in or pursuant to the Loan Documents are true and correct in all material
respects on and as of the First Amendment Closing Date as if made on and as of such date, except for representations and warranties
expressly stated to relate to a specified date, in which case such representations and warranties are true and correct in all material
respects as of such earlier date (it being understood and agreed that the reference in Section 3.12 of the Credit Agreement to
 “the Closing Date, immediately after the consummation of the Transactions to occur on the Closing Date” shall be deemed
to refer instead to “the First Amendment Closing Date, immediately after giving effect to the transactions to be consummated
on the First Amendment Closing Date”).


 


SECTION
6. Conditions Precedent to Effectiveness of this Agreement. This Agreement shall become effective on the first date
(the “First Amendment Closing Date”) on which the following conditions precedent are satisfied or waived:


 


(i)
the Administrative Agent (or its counsel) shall have received counterparts of this Agreement that, when taken together,
bear the signatures of (1) each Borrower, (2) Holdings, (3) the Reaffirming Loan Parties (as defined in Section 9 hereof), (4)
the Administrative Agent and (5) the Incremental Term Loan Lender;


 






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(ii)
all fees and expenses in connection with this Agreement or under any other Loan Document or other agreement with any Borrower
relating to the transactions contemplated hereby (including reasonable and documented out-of-pocket legal fees and expenses required
to be paid by the Parent Borrower pursuant to Section 9.03(a) of the Credit Agreement) payable by the Parent Borrower on or before
the First Amendment Closing Date shall have been paid to the extent then due; provided that any such expenses shall be required
to be paid, as a condition precedent to the First Amendment Closing Date, only to the extent invoiced at least two (2) Business
Days prior to the First Amendment Closing Date;


 


(iii)
the Administrative Agent shall have received a duly executed officer’s certificate of the Parent Borrower certifying,
as of the First Amendment Closing Date, that (A) each of the representations and warranties set forth in Section 5 above are true
and correct on and as of the First Amendment Closing Date and (B) no Default or Event of Default has occurred and is continuing
both before and immediately after giving effect to this Agreement and the transactions contemplated hereby;


 


(iv)
the Administrative Agent shall have received the following:


 


(i)             
a copy of a short form certificate of the Secretary of State or other applicable Governmental Authority of the jurisdiction
in which each Loan Party is organized, dated reasonably near the First Amendment Closing Date, certifying that such Loan Party
is duly organized and in good standing or full force and effect under the laws of such jurisdiction; and


 


(ii)            
a certificate of the Secretary, Assistant Secretary or other appropriate Responsible Officer of each Loan Party,
dated the First Amendment Closing Date and certifying (1) (x) that attached thereto is a true and complete copy of the by-laws,
limited liability company agreement or limited partnership agreement, as applicable, of such Loan Party as in effect on the First
Amendment Closing Date and at all times since a date prior to the date of the resolutions described in clause (2) below or (y)
that the by-laws, limited liability company agreement or limited partnership agreement, as applicable, of such Loan Party provided
in the certificate delivered on the Closing Date are still in effect, (2) (x) that attached thereto is a true and complete copy
of resolutions duly adopted by the board of directors, board of managers, members or other governing body, as applicable, of such
Loan Party authorizing the execution, delivery and performance of this Agreement and the borrowings hereunder, in the case of the
Borrowers, and any Loan Documents to which each such Loan Party is a party, and that such resolutions have not been modified, rescinded
or amended and are in full force and effect or (y) that the resolutions adopted by the board of directors, board of managers, members
or other governing body, as applicable, of such Loan Party in connection with the entry into the Credit Agreement on the Closing
Date have not been modified, rescinded or amended and are in full force and effect, and (3) (x) as to the incumbency and specimen
signature of each officer executing this Agreement or any other Loan Document or any other document delivered in connection herewith
on behalf of such Loan Party or (y) that the incumbency and specimen signature of each officer executing this Agreement provided
on the Closing Date have not changed;


 






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(v)
the Administrative Agent shall have received, on behalf of itself and the Lenders and each Issuing Bank, an opinion of Simpson
Thacher & Bartlett LLP, in its capacity as New York counsel to the Loan Parties, dated the First Amendment Closing Date and
addressed to the Administrative Agent and each Lender and Issuing Bank and in form and substance consistent with the opinions delivered
by such counsel on the Closing Date, taking into account the nature of this Agreement and the transactions contemplated hereby;


 


(vi)
delivery of a Borrowing Request pursuant to Section 2.03 of the Credit Agreement;


 


(vii)
the Borrowers shall have paid all unpaid interest and any other amounts in respect of the Initial Term Loans that has accrued
to but excluding the First Amendment Closing Date; and


 


(viii)
no later than three Business Days in advance of the First Amendment Closing Date, the Administrative Agent shall have received
all documentation and other information reasonably requested with respect to any Loan Party (including any entities that will become
Loan Parties in connection with the transactions contemplated by this Agreement) in writing by the Administrative Agent (including
on behalf of the Lenders) at least ten Business Days in advance of the First Amendment Closing Date, which documentation or other
information is required by regulatory authorities under applicable “know your customer” and anti-money laundering rules
and regulations, including the USA PATRIOT Act.


 


SECTION
7. Reserved.


 


SECTION
8. Effect of this Agreement. Except as expressly set forth herein, this Agreement shall not by implication or otherwise
limit, impair, constitute a waiver of, or otherwise affect the rights and remedies of the Lenders or the Agents under, the Credit
Agreement or any other Loan Document, and shall not alter, modify, amend or in any way affect any of the terms, conditions, obligations,
covenants or agreements contained in the Credit Agreement or any other Loan Document, all of which are ratified and affirmed in
all respects and shall continue in full force and effect. Nothing herein shall be deemed to entitle any Loan Party to a consent
to, or a waiver, amendment, modification or other change of, any of the terms, conditions, obligations, covenants or agreements
contained in the Credit Agreement or any other Loan Document in similar or different circumstances. Nothing herein can or may be
construed as a novation of the Credit Agreement or any other Loan Document. This Agreement shall apply and be effective only with
respect to the provisions of the Credit Agreement specifically referred to herein. After the First Amendment Closing Date, any
reference to the Credit Agreement shall mean the Credit Agreement as modified hereby.


 






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SECTION
9. Reaffirmation. Each of Holdings, each Borrower and each Guarantor identified on the signature pages hereto (collectively,
Holdings, the Borrowers and such Guarantors, the “Reaffirming Loan Parties”) hereby acknowledges that it expects
to receive substantial direct and indirect benefits as a result of this Agreement and the transactions contemplated hereby. Each
Reaffirming Loan Party hereby confirms its respective guarantees (including in respect of the Incremental Term Loans), pledges
and grants of security interests, as applicable, under each of the Loan Documents to which it is party, and agrees that, notwithstanding
the effectiveness of this Agreement and the transactions contemplated hereby, such guarantees, pledges and grants of security interests
shall continue to be in full force and effect and shall accrue to the benefit of the Secured Parties (including in respect of the
Incremental Term Loan Lender). Each of the Reaffirming Loan Parties hereby reaffirms its obligations under each provision of each
Loan Document to which it is party.


 


SECTION
10. Counterparts. This Agreement may be executed in one or more counterparts, each of which shall be deemed an original,
but all of which together shall constitute one and the same instrument. Delivery by telecopier (or other electronic transmission)
of an executed counterpart of a signature page to this Agreement shall be effective as delivery of an original executed counterpart
of this Agreement.


 


SECTION
11. Headings. Section headings used herein are for convenience of reference only, are not part of this Agreement
and are not to affect the construction of, or to be taken into consideration in interpreting, this Agreement.


 


SECTION
12. Governing Law; Jurisdiction, etc. This Agreement shall be construed in accordance with and governed by the laws
of the State of New York. The provisions of Sections 9.10 and 9.11 of the Credit Agreement shall apply to this Agreement, mutatis
mutandis.


 


[Remainder of page intentionally left blank]


 






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IN WITNESS WHEREOF, the
parties hereto have caused this Agreement to be duly executed by their respective authorized officers as of the day and year first
above written.


 


	 	EQT AVATAR INTERMEDIATE, Inc., as Holdings
	 	 	 
	 	By:	/s/ Jason Howard
	 	Name:   Jason Howard
	 	Title:     President
	 	 	 
	 	By: 	/s/ Robert Bradburn
	 	Name:   Robert Bradburn
	 	Title:
    Vice President and Secretary
	 	 	 
	 	EQT AVATAR HOLDINGS, Inc., as a Loan Guarantor
	 	 	 
	 	By:	/s/ Jason Howard
	 	Name:   Jason Howard
	 	Title:     President
	 	 	 
	 	By: 	/s/ Robert Bradburn
	 	Name:   Robert Bradburn
	 	Title:     Vice President and Secretary
	 	 	 
	 	CERTARA HOLDCO, Inc., as the Parent Borrower
	 	 	 
	 	By: 	/s/ Andrew Schemick
	 	Name:   Andrew Schemick
	 	Title:     Chief Financial Officer and Treasurer
	 	 	 
	 	CERTARA USA, Inc., as the Co-Borrower
	 	 	 
	 	By: 	/s/ Andrew Schemick
	 	Name:   Andrew Schemick
	 	Title:     Chief Financial Officer and Treasurer


 






    


     


    

 


	 	SUBSIDIARY GUARANTORS
	 	 	 
	 	CERTARA HOLDING, INC.
	 	 	 
	 	By:	/s/ Andrew Schemick
	 	Name:	        Andrew Schemick
	 	Title:	        Chief Financial Officer and Treasurer
	 	 	 
	 	MBDD US, LLC
	 	 	 
	 	By: 	/s/ Andrew Schemick
	 	Name:	        Andrew Schemick
	 	Title:	        Chief Financial Officer and Treasurer
	 	 	 
	 	TRIPOS INVESTMENTS, L.L.C.
	 	 	 
	 	By:	/s/ Andrew Schemick
	 	Name:	        Andrew Schemick
	 	Title: 	        Chief Financial Officer and Treasurer
	 	 	 
	 	SYNCHROGENIX INFORMATION STRATEGIES, LLC
	 	 	 
	 	By:	/s/ Andrew Schemick
	 	Name:	        Andrew Schemick
	 	Title:	        Chief Financial Officer and Treasurer
	 	 	 
	 	CERTARA, L.P.
	 	 
	 	By:	/s/ Andrew Schemick
	 	Name:	         Andrew Schemick
	 	Title:	        Chief Financial Officer and Treasurer


 






    


     


    

 


 


 


 


	 	
JEFFERIES FINANCE LLC, as 
 Administrative Agent and Incremental Term
 Loan Lender
	 	 	 
	 	 	by
	 	 	 	/s/ J. Paul McDonnell
	 	 	 	Name:  J. Paul McDonnell
	 	 	 	Title:    Managing Director


 






    


     


    

 


SCHEDULE I


to the First Amendment


 


Incremental Term
Commitments 


 





	Incremental Term Loan Lender	 	Incremental
Term
 Commitment
	 
	Jefferies Finance LLC	 	$	25,000,000	 
	Total	 	$	25,000,000