siox8k12g3exhibit41






                                                                                                                               Exhibit 4.1    SG    INCORPORATED UNDER THE                                                                          CUSIP 829399 10 4    LAWS OF THE STATE                                                                                                      SEE REVERSE FOR CERTAIN      OF DELAWARE                                                                                    DEFINITIONS AND LEGENDS    This certifies that                                                                                                                                BY:                                                                                                                                         COUNTERSIGNED  AND  REGISTERED:                                                                                                                                       AMERICAN  STOCK  TRANSFER & TRUST COMPANY, LLC                                                                                                                                     BOKY,N)TRANSFER AGENT  (BROOKLYN,  NY)   is the record holder of         FULLY PAID AND NONASSESSABLE SHARES OF COMMON STOCK, $0.00001 PAR VALUE PER SHARE, OF                                          Sio Gene Therapies Inc.  transferable on the books of the Corporation in person or by duly authorized attorney upon surrender of this Certificate properly   endorsed. This Certificate is not valid until countersigned by the Transfer Agent and registered by the Registrar.         AUTHORIZED  SIGNATURE  WITNESS the facsimile seal of the Corporation and the facsimile signatures of its duly authorized officers.                                                                                                                                    AND  REGISTRAR  Dated:                                                             THERAP                                                          E      IE                                                          N  OR   S                                                         E  RP AT                                                        G  O    E  IN                                                          C                                                        O          C                                                        I                                                                    .                                                        S                   PRINCIPAL EXECUTIVE OFFICER             SEAL              PRINCIPAL FINANCIAL OFFICER                                                          November 12,                                                       #    2020                                                                   #                                                         D                                                          E       E                                                           L A W A R





 






        The Corporation shall furnish without charge to each stockholder who so requests a statement of the powers, designations,   preferences and relative, participating, optional or other special rights of each class of stock of the Corporation or series thereof   and the qualifications, limitations or restrictions of such preferences and/or rights. Such requests shall be made to the Corporation’s   Secretary at the principal office of the Corporation.          KEEP THIS CERTIFICATE IN A SAFE PLACE. IF IT IS LOST, STOLEN,OR DESTROYED THE CORPORATION WILL REQUIRE   A BOND INDEMNITY AS A CONDITION TO THE ISSUANCE OF A REPLACEMENT CERTIFICATE.          The following abbreviations, when used in the inscription on the face of this certificate, shall be construed as though they were written out in full according to applicable   laws or regulations:  TEN COM        –   as tenants in common                                                                                               UNIF GIFT MIN ACT  –  ......................... Custodian ......................... TEN ENT        –   as tenants by the entireties                                                                                                                          (Cust)                      (Minor) JT TEN         –   as joint tenants with right of                                                                                                                under Uniform Gifts to Minors                     survivorship and not as tenants                                                                                                              Act..............................................................................                      in common                                                                                                                                                      (State) COM PROP  –   as community property                                                                                                   UNIF TRF MIN ACT  –        ................. Custodian (until age ..................)                                                                                                                                                                     (Cust)                                                                                                                                        ..................................... under Uniform Transfers                                                                                                                                                                             (Minor)                                                                                                                                                                  to Minors Act............................................................                                                                                                                                                                                                       (State)                                                                    Additional abbreviations may also be used though not in the above list.         FOR VALUE RECEIVED, _____________________________________________________  hereby sell(s), assign(s) and transfer(s) unto     PLEASE INSERT SOCIAL SECURITY OR OTHER         IDENTIFYING NUMBER OF ASSIGNEE                                                     (PLEASE PRINT OR TYPEWRITE NAME AND ADDRESS, INCLUDING ZIP CODE, OF ASSIGNEE)                                                                                                                                                                                                          shares of the capital stock represented by within Certificate, and do hereby irrevocably constitute and appoint                                                                                                                                                                                           attorney-in-fact to transfer the said stock on the books of the within named Corporation with full power of the substitution in the premises.   Dated                                                                  X                                                                 X  Signature(s) Guaranteed:                                            NOTICE:        THE SIGNATURE TO THIS ASSIGNMENT MUST CORRESPOND WITH THE NAME AS WRITTEN UPON THE                                                                                       FACE OF THE CERTIFICATE IN EVERY PARTICULAR, WITHOUT ALTERATION OR ENLARGEMENT OR ANY                                                                                       CHANGE WHATSOEVER.    By  THE SIGNATURE(S) SHOULD BE GUARANTEED BY AN ELIGIBLE GUARANTOR INSTITUTION, (BANKS, STOCKBROKERS,   SAVINGS AND LOAN ASSOCIATIONS AND CREDIT UNIONS WITH MEMBERSHIP IN AN APPROVED SIGNATURE   GUARANTEE MEDALLION PROGRAM), PURSUANT TO S.E.C. RULE 17Ad-15. GUARANTEES BY A NOTARY PUBLIC ARE NOT   ACCEPTABLE. SIGNATURE GUARANTEES MUST NOT BE DATED.