2005 Amended and Restated Stock Option Plan



 Exhibit 10.8 

NEOGENIX ONCOLOGY, INC. 

2005 AMENDED AND RESTATED STOCK OPTION PLAN 
  

	1.	DEFINITIONS. 

 Unless
otherwise specified or unless the context otherwise requires, the following terms, as used in this Neogenix Oncology, Inc. 2005 Amended and Restated Stock Option Plan, have the following meanings: 

“Affiliate” means a corporation which, for purposes of Section 424 of the Code, is a parent or subsidiary of the
Company, direct or indirect. 
 “Board of Directors” means the Board of Directors of the Company. 

“Change in Control” means the first to occur of the following: 

(1) the acquisition by any individual, entity or group (within the meaning of Section 13(d)(3) or 14(d)(2) of the
Exchange Act) (a “Person”) of beneficial ownership (within the meaning of Rule 13d-3 promulgated under the Exchange Act) of 30% or more of either (i) the then-outstanding shares of common stock of the Company (the “Outstanding
Company Common Stock”) or (ii) the combined voting power of the then-outstanding voting securities of the Company entitled to vote generally in the election of directors (the “Outstanding Company Voting Securities”); provided,
however, that, for purposes of this definition, the following acquisitions shall not constitute a Change in Control: (A) any acquisition directly from the Company, (B) any acquisition by the Company, (C) any acquisition by any
employee benefit plan (or related trust) sponsored or maintained by the Company or one of its affiliates, or (D) any acquisition pursuant to a transaction that complies with (3)(i), (3)(ii) and (3)(iii) below; 

(2) individuals who, as of the date hereof, constitute the Board of Directors (the “Incumbent Board”) cease for
any reason to constitute at least a majority of the Board of Directors; provided, however, that any individual becoming a director subsequent to the date hereof whose election or nomination for election by the Company’s stockholders was
approved by a vote of at least a majority of the directors then comprising the Incumbent Board shall be considered as though such individual were a member of the Incumbent Board, but excluding, for this purpose, any such individual whose initial
assumption of office occurs as a result of an actual or threatened election contest with respect to the election or removal of directors or other actual or threatened solicitation of proxies or consents by or on behalf of a Person other than the
Board of Directors; or 







 (3) consummation of a reorganization, merger, statutory share exchange or
consolidation or similar corporate transaction involving the Company or any of its subsidiaries, a sale or other disposition of all or substantially all of the assets of the Company, or the acquisition of assets or stock of another entity by the
Company or any of its subsidiaries (each, a “Business Combination”), in each case, unless, following such Business Combination, (i) all or substantially all of the individuals and entities that were the beneficial owners of the
Outstanding Company Common Stock and the Outstanding Company Voting Securities immediately prior to such Business Combination beneficially own, directly or indirectly, more than 50% of the then-outstanding shares of common stock and the combined
voting power of the then-outstanding voting securities entitled to vote generally in the election of directors, as the case may be, of the corporation or entity resulting from such Business Combination (including, without limitation, a corporation
or entity that, as a result of such transaction, owns the Company or all or substantially all of the Company’s assets either directly or through one or more subsidiaries) in substantially the same proportions as their ownership immediately
prior to such Business Combination of the Outstanding Company Common Stock and the Outstanding Company Voting Securities, as the case may be, (ii) no Person (excluding any employee benefit plan (or related trust) of the Company or any
corporation or entity resulting from such Business Combination) beneficially owns, directly or indirectly, 30% or more of, respectively, the then-outstanding shares of common stock of the corporation or entity resulting from such Business
Combination or the combined voting power of the then-outstanding voting securities of such corporation or entity, except to the extent that such ownership existed prior to the Business Combination, and (iii) at least a majority of the members
of the board of directors of the corporation or entity resulting from such Business Combination were members of the Incumbent Board at the time of the execution of the initial agreement or of the action of the Board of Directors providing for such
Business Combination. 
 “Code” means the United States Internal Revenue Code of 1986, as amended. 

“Committee” means the Compensation Committee of the Board of Directors to which the Board of Directors has delegated
power to act under or pursuant to the provisions of the Plan. 
 “Common Stock” means shares of the
Company’s common stock, $0.00001 par value per share. 
 “Company” means Neogenix Oncology, Inc., a
Maryland corporation. 
 “Consultant” means a consultant or advisor only if such person (1) is a natural
person, (2) provides bona fide services to the Company, and (3) the services are not in connection with the offer or sale of securities in a capital-raising transaction, and do not directly or indirectly promote or maintain a market for
the Company’s securities. 
  

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 “Director” means any individual who is a member of the Board of Directors;
provided, however, that any Director who is employed by the Company shall be considered an Employee under the Plan. 

“Disability” or “Disabled” means permanent and total disability as defined in Section 22(e)(3) of
the Code. 
 “Effective Date” means March 20, 2010, the date of approval by the Company’s stockholders
of the Plan. 
 “Employee” means any employee of the Company or of an Affiliate (including, without limitation,
an employee who is also serving as an officer or director of the Company or of an Affiliate), designated by the Committee to be eligible to be granted one or more Options under the Plan. 

“Exchange Act” means the Securities Exchange Act of 1934, as amended from time to time, or any successor act thereto.

 “Fair Market Value” of a Share of Common Stock means: 

(1) If the Common Stock is listed on a national securities exchange or traded in the over-the-counter market and sales prices are
regularly reported for the Common Stock, the closing or last price of the Common Stock on the Composite Tape or other comparable reporting system for the trading day immediately preceding the applicable date; 

(2) If the Common Stock is not traded on a national securities exchange but is traded on the over-the-counter market, if sales prices are
not regularly reported for the Common Stock for the trading day referred to in clause (1), and if bid and asked prices for the Common Stock are regularly reported, the mean between the bid and the asked price for the Common Stock at the close
of trading in the over-the-counter market for the trading day on which Common Stock was traded immediately preceding the applicable date; and 

(3) If the Common Stock is neither listed on a national securities exchange nor traded in the over-the-counter market, such value as the
Committee, in good faith, shall determine. 
 “Insider” means an individual who is, on the relevant date, an
executive officer, director or ten percent (10%) beneficial owner of any class of the Company’s equity securities that is registered pursuant to Section 12 of the Exchange Act, all as defined under Section 16 of the Exchange Act.

  

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 “ISO” means an option meant to qualify as an incentive stock option under
Section 422 of the Code. 
 “Non-Qualified Option” means an option which is not intended to qualify as an
ISO. 
 “Option” means an ISO or Non-Qualified Option granted under the Plan. 

“Option Agreement” means an agreement between the Company and a Participant delivered pursuant to the Plan, in such form
as the Committee shall approve. 
 “Participant” means an Employee, Director or Consultant of the Company or an
Affiliate to whom one or more Options are granted under the Plan. As used herein, “Participant” shall include “Participant’s Survivors” or “Participant’s Permitted Transferees” where the context requires.

 “Permitted Transferee” means an Employee’s Family Member (as defined below) who has acquired
Non-Qualified Options from such Employee through a gift or a domestic relations order. For purposes of this Plan, “Family Member” means an Employee making a transfer of a Non-Qualified Option and his or her child, stepchild, grandchild,
parent, stepparent, grandparent, spouse, former spouse, sibling, niece, nephew, mother-in-law, father-in-law, brother-in-law, or sister-in-law, including adoptive relationships; any person sharing the Employee’s household (other than a tenant
or employee); a trust in which the foregoing persons have more than fifty percent (50%) of the beneficial interest; a foundation in which the foregoing persons control the management of assets; and any other entity in which the foregoing
persons own more than fifty percent (50%) of the voting interests. 
 “Plan” means this Neogenix Oncology,
Inc. 2005 Amended and Restated Stock Option Plan. 
 “Prior Plan” means the Neogenix Oncology, Inc. 2005
Employee, Director and Consultant Stock Option Plan in effect prior to the Effective Date. 
 “Section 409A”
means Code Section 409A and the regulations and other guidance issued thereunder. 
 “Shares” means shares
of the Common Stock as to which Options have been or may be granted under the Plan or any shares of capital stock into which the Shares are changed or for which they are exchanged within the provisions of Paragraph 3 of the Plan. The Shares
issued upon exercise of Options granted under the Plan may be authorized and unissued shares or shares held by the Company in its treasury, or both. 
  

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 “Survivor” means a deceased Participant’s legal representatives and/or
any person or persons who acquired the Participant’s rights to an Option by will or by the laws of descent and distribution. 
  

	2.	PURPOSES OF THE PLAN. 


The Plan is intended to encourage ownership of Shares by Employees, Directors and Consultants in order to attract such people, to induce
them to work for the benefit of the Company or of an Affiliate and to provide additional incentive for them to promote the success of the Company or of an Affiliate. The Plan provides for the granting of ISOs and Non-Qualified Options. 

 

	3.	SHARES SUBJECT TO THE PLAN. 


A. Number of Shares Available for Options: The number of Shares which may be issued under ISOs or Non-Qualified Options shall be
eleven million (11,000,000), or the equivalent of such number of Shares after the Committee, in its sole discretion, has interpreted the effect of any stock split, stock dividend, combination, recapitalization or similar transaction in accordance
with Paragraph 15 of the Plan. 
 B. Share Counting and Reacquired Shares: If an Option ceases to be
“outstanding”, in whole or in part, the Shares which were subject to such Option shall be available for the granting of other Options under the Plan. Any Option shall be treated as “outstanding” until such Option is exercised in
full, or terminates or expires under the provisions of the Plan, or by agreement of the parties to the pertinent Option Agreement. 

C. Prior Awards: Options granted before the Effective Date to persons who were not Employees, Directors or Consultants on the
grant date shall be governed by the terms of the Plan in effect prior to the Effective Date. From and after the Effective Date, Options shall be granted under the Plan solely to Employees, Directors and Consultants. 

 

	4.	ADMINISTRATION OF THE PLAN. 


Subject to the provisions of the Plan, the Committee is authorized to: 

 

	 	a.	Interpret the provisions of the Plan or of any Option or Option Agreement and to make all rules and determinations which it deems necessary or advisable for the
administration of the Plan; 

  

	 	b.	Determine which Employees, Directors and Consultants shall be granted Options; 


 

	 	c.	Determine the number of Shares for which an Option or Options shall be granted; 


 

	 	d.	Specify the terms and conditions upon which an Option or Options may be granted; and 


 

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	 	e.	Adopt any sub-plans applicable to residents of any specified jurisdiction as it deems necessary or appropriate in order to comply with or take advantage of any tax laws
applicable to the Company or to Plan Participants or to otherwise facilitate the administration of the Plan, which sub-plans may include additional restrictions or conditions applicable to Options or Shares acquired upon exercise of Options.


 provided, however, that all such interpretations, rules, determinations, terms and conditions shall be made and prescribed in
the context of preserving the tax status under Section 422 of the Code of those Options which are designated as ISOs. Subject to the foregoing, the interpretation and construction by the Committee of any provisions of the Plan or of any Option
granted under it shall be final, unless otherwise determined by the Board of Directors. 
 If permissible under applicable law,
the Committee may allocate all or any portion of its responsibilities and powers to any one or more of its members and may delegate all or any portion of its responsibilities and powers to any other person selected by it. Any such allocation or
delegation may be revoked by the Committee at any time. 
  

	5.	ELIGIBILITY FOR PARTICIPATION. 


The Committee will, in its sole discretion, name the Participants in the Plan, provided, however, that each Participant must be an
Employee, Director or Consultant of the Company or of an Affiliate at the time an Option is granted. Notwithstanding the foregoing, the Committee may authorize the grant of an Option to a person not then an Employee, director or consultant of the
Company or of an Affiliate; provided, however, that the actual grant of such Option shall be conditioned upon such person becoming eligible to become a Participant at or prior to the time of the execution of the Option Agreement evidencing such
Option. ISOs may be granted only to Employees. Non-Qualified Options may be granted to any Employee, Director or Consultant of the Company or an Affiliate. The granting of any Option to any individual shall neither entitle that individual to, nor
disqualify him or her from, participation in any other grant of Options. 
  

	6.	TERMS AND CONDITIONS OF OPTIONS. 


Each Option shall be set forth in writing in an Option Agreement, duly executed by the Company and, to the extent required by law or
requested by the Company, by the Participant. The Committee may provide that Options be granted subject to such terms and conditions, consistent with the terms and conditions specifically required under this Plan, as the Committee may deem
appropriate including, without limitation, subsequent approval by the shareholders of the Company of this Plan or any amendments thereto. The Option Agreements shall be subject to at least the following terms and conditions: 

 

	 	A.	Non-Qualified Options: Each Option intended to be a Non-Qualified Option shall be subject to the terms and conditions which the Committee determines to be
appropriate and in the best interest of the Company, subject to the following minimum standards for any such Non-Qualified Option: 

  

	 	a.	Option Price: Each Option Agreement shall state the option price (per share) of the Shares covered by each Option, which option price shall be determined by the
Committee but shall not be less than 100% of the Fair Market Value per share of the Shares on the date of the grant of the Option; 

  

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	 	b.	Each Option Agreement shall state the number of Shares to which it pertains; 


 

	 	c.	Each Option Agreement shall state the date or dates on which it first is exercisable and the date after which it may no longer be exercised, and may provide that the
Option rights accrue or become exercisable in installments over a period of months or years, or upon the occurrence of certain conditions or the attainment of stated goals or events; and 


 

	 	d.	Exercise of any Option may be conditioned upon the Participant’s execution of a Share purchase agreement in form satisfactory to the Committee providing for
certain protections for the Company and its other shareholders, including requirements that: 

  

	 	i.	The Participant’s or the Participant’s Survivors’ right to sell or transfer the Shares may be restricted; and 


 

	 	ii.	The Participant or the Participant’s Survivors may be required to execute letters of investment intent and must also acknowledge that the Shares will bear legends
noting any applicable restrictions. 

  

	 	B.	ISOs: Each Option intended to be an ISO shall be issued only to an Employee and be subject to the following terms and conditions, with such additional
restrictions or changes as the Committee determines are appropriate but not in conflict with Section 422 of the Code and relevant regulations and rulings of the Internal Revenue Service: 


 

	 	a.	Minimum standards: The ISO shall meet the minimum standards required of Non-Qualified Options, as described in Paragraph 6(A) above, except clause (a) thereunder.


  

	 	b.	Option Price: Immediately before the ISO is granted, if the Participant owns, directly or by reason of the applicable attribution rules in Section 424(d) of the
Code: 

  

	 	i.	10% or less of the total combined voting power of all classes of stock of the Company or an Affiliate, the Option price per share of the Shares covered by each
ISO shall not be less than 100% of the Fair Market Value per share of the Shares on the date of the grant of the Option; or 

  

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	 	ii.	More than 10% of the total combined voting power of all classes of stock of the Company or an Affiliate, the Option price per share of the Shares covered by each ISO
shall not be less than 110% of the said Fair Market Value on the date of grant. 

  

	 	c.	Term of Option: For Participants who own: 

  

	 	i.	10% or less of the total combined voting power of all classes of stock of the Company or an Affiliate, each ISO shall terminate not more than ten years from the
date of the grant or at such earlier time as the Option Agreement may provide; or 

  

	 	ii.	More than 10% of the total combined voting power of all classes of stock of the Company or an Affiliate, each ISO shall terminate not more than five years from the date
of the grant or at such earlier time as the Option Agreement may provide. 

  

	 	d.	Limitation on Yearly Exercise: The Option Agreements shall restrict the amount of ISOs which may become exercisable in any calendar year (under this or any other ISO
plan of the Company or an Affiliate) so that the aggregate Fair Market Value (determined at the time each ISO is granted) of the stock with respect to which ISOs are exercisable for the first time by the Participant in any calendar year does not
exceed $100,000. 

  

	7.	EXERCISE OF OPTIONS AND ISSUE OF SHARES. 


An Option (or any part or installment thereof) shall be exercised by giving written notice to the Company or its designee, together with
provision for payment of the full purchase price in accordance with this Paragraph for the Shares as to which the Option is being exercised, and upon compliance with any other condition(s) set forth in the Option Agreement. Such notice shall be
signed by the person exercising the Option, shall state the number of Shares with respect to which the Option is being exercised and shall contain any representation required by the Plan or the Option Agreement. Payment of the purchase price for the
Shares as to which such Option is being exercised shall be made (a) in United States dollars in cash or by check, or (b) at the discretion of the Committee, through delivery of shares of Common Stock having a Fair Market Value equal as of
the date of the exercise to the cash exercise price of the Option and held for at least six months, or (c) at the discretion of the Committee, in accordance with a cashless exercise program established with a securities brokerage firm, and
approved by the Committee, or (d) at the discretion of the Committee, by any combination of (a), (b) and (c) above. Notwithstanding the foregoing, the Committee shall accept only such payment on exercise of an ISO as is permitted by
Section 422 of the Code. 
 The Company shall then reasonably promptly deliver the Shares as to which such Option was
exercised to the Participant (or to the Participant’s Survivors, as the case may be). In 
  

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determining what constitutes “reasonably promptly,” it is expressly understood that the issuance and delivery of the Shares may be delayed by the Company in order to comply with any law
or regulation (including, without limitation, state securities or “blue sky” laws) which requires the Company to take any action with respect to the Shares prior to their issuance. The Shares shall, upon delivery, be fully paid,
non-assessable Shares. 
 The Committee shall have the right to accelerate the date of exercise of any installment of any
Option; provided that the Committee shall not accelerate the exercise date of any installment of any Option granted to any Employee as an ISO (and not previously converted into a Non-Qualified Option pursuant to Paragraph 19) if such
acceleration would violate the annual vesting limitation contained in Section 422(d) of the Code, as described in Paragraph 6.B.d. 

The Committee may, in its discretion, amend any term or condition of an outstanding Option provided (i) such term or condition as
amended is permitted by the Plan, (ii) any such amendment shall be made only with the consent of the Participant to whom the Option was granted, or in the event of the death of the Participant, the Participant’s Survivors, if the amendment
is adverse to the Participant, and (iii) any such amendment of any ISO shall be made only after the Committee determines whether such amendment would constitute a “modification” of any Option which is an ISO (as that term is defined
in Section 424(h) of the Code) or would cause any adverse tax consequences for the holder of such ISO. 
  

	8.	RIGHTS AS A SHAREHOLDER. 


No Participant to whom an Option has been granted shall have rights as a shareholder with respect to any Shares covered by such Option,
except after due exercise of the Option and tender of the full purchase price for the Shares being purchased pursuant to such exercise and registration of the Shares in the Company’s share register in the name of the Participant. 

 

	9.	ASSIGNABILITY AND TRANSFERABILITY OF OPTIONS. 


By its terms, an Option granted to a Participant shall not be transferable by the Participant other than (i) by will or by the laws
of descent and distribution, or (ii) to a Permitted Transferee, if approved by the Committee in its discretion. Notwithstanding the foregoing, an ISO shall not be transferrable except in compliance with clause (i) above. The designation of
a beneficiary of an Option by a Participant, with the prior approval of the Committee and in such form as the Committee shall prescribe, shall not be deemed a transfer prohibited by this Paragraph. Except as provided above, an Option shall be
exercisable, during the Participant’s lifetime, only by such Participant (or by his or her legal representative) and shall not be assigned, pledged or hypothecated in any way (whether by operation of law or otherwise) and shall not be subject
to execution, attachment or similar process. Any attempted transfer, assignment, pledge, hypothecation or other disposition of any Option or of any rights granted thereunder contrary to the provisions of this Plan, or the levy of any attachment or
similar process upon an Option, shall be null and void. 
  

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	10.	EFFECT OF TERMINATION OF SERVICE OTHER THAN “FOR CAUSE” OR DEATH OR DISABILITY. 


Except as otherwise provided in a Participant’s Option Agreement, in the event of a termination of service (whether as an Employee,
Director or Consultant) with the Company or an Affiliate before the Participant has exercised an Option, the following rules apply: 
  

	 	a.	A Participant who ceases to be an Employee, Director or Consultant of the Company or of an Affiliate (for any reason other than termination “for cause”,
Disability, or death for which events there are special rules in Paragraphs 11, 12, and 13, respectively), may exercise any Option granted to him or her to the extent that the Option is exercisable on the date of such termination of service, but
only within such term as the Committee has designated in a Participant’s Option Agreement. 

  

	 	b.	Except as provided in Subparagraph (c) below, or Paragraph 12 or 13, in no event may an Option intended to be an ISO, be exercised later than three months after
the Participant’s termination of employment. 

  

	 	c.	The provisions of this Paragraph, and not the provisions of Paragraph 12 or 13, shall apply to a Participant who subsequently becomes Disabled or dies after the
termination of employment, director status or consultancy, provided, however, in the case of a Participant’s Disability or death within three months after the termination of employment, director status or consultancy, the Participant or the
Participant’s Survivors may exercise the Option within one year after the date of the Participant’s termination of service, but in no event after the date of expiration of the term of the Option. 


 

	 	d.	Notwithstanding anything herein to the contrary, if subsequent to a Participant’s termination of employment, termination of director status or termination of
consultancy, but prior to the exercise of an Option, the Board of Directors determines that, either prior or subsequent to the Participant’s termination, the Participant engaged in conduct which would constitute “cause”, then such
Participant shall forthwith cease to have any right to exercise any Option. 

  

	 	e.	A Participant to whom an Option has been granted under the Plan who is absent from work with the Company or with an Affiliate because of temporary disability (any
disability other than a permanent and total Disability as defined in Paragraph 1 hereof), or who is on leave of absence for any purpose, shall not, during the period of any such absence, be deemed, by virtue of such absence alone, to have
terminated such Participant’s employment, director status or consultancy with the Company or with an Affiliate, except as the Committee may otherwise expressly provide. 


 

	 	f.	 Except as required by law or as set forth in a Participant’s Option Agreement, Options granted under the Plan shall not be affected by any change
of a 


  

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Participant’s status within or among the Company and any Affiliates, so long as the Participant continues to be an Employee, Director or Consultant of the Company or any Affiliate. Except as
required by law or as set forth in a Participant’s Option Agreement, if a Participant is employed by an entity that ceases to be an Affiliate, the Participant will be treated as having terminated employment with the Company.


  

	11.	EFFECT OF TERMINATION OF SERVICE “FOR CAUSE”. 


Except as otherwise provided in a Participant’s Option Agreement, the following rules apply if the Participant’s service
(whether as an Employee, Director or Consultant) with the Company or an Affiliate is terminated “for cause” prior to the time that all his or her outstanding Options have been exercised: 

 

	 	a.	All outstanding and unexercised Options as of the time the Participant is notified his or her service is terminated “for cause” will immediately be forfeited.


  

	 	b.	For purposes of this Plan, “cause” shall include (and is not limited to) dishonesty with respect to the Company or any Affiliate, insubordination, substantial
malfeasance or non-feasance of duty, unauthorized disclosure of confidential information, breach by the Participant of any provision of any employment, consulting, advisory, nondisclosure, non-competition or similar agreement between the Participant
and the Company or any Affiliate, and conduct substantially prejudicial to the business of the Company or any Affiliate. The determination of the Committee as to the existence of “cause” will be conclusive on the Participant and the
Company. 

  

	 	c.	“Cause” is not limited to events which have occurred prior to a Participant’s termination of service, nor is it necessary that the Committee’s
finding of “cause” occur prior to termination. If the Committee determines, subsequent to a Participant’s termination of service but prior to the exercise of an Option, that either prior or subsequent to the Participant’s
termination the Participant engaged in conduct which would constitute “cause,” then the right to exercise any Option is forfeited. 

  

	 	d.	Any definition in an agreement between the Participant and the Company or an Affiliate, which contains a conflicting definition of “cause” for termination and
which is in effect at the time of such termination, shall supersede the definition in this Plan with respect to that Participant. 

  

	12.	EFFECT OF TERMINATION OF SERVICE FOR DISABILITY. 


Except as otherwise provided in a Participant’s Option Agreement, a Participant who ceases to be an Employee, Director or Consultant
of the Company or of an Affiliate by reason of Disability may exercise any Option granted to such Participant: 
  

	 	a.	To the extent that the Option has become exercisable but has not been exercised on the date of Disability; and 


 

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	 	b.	In the event rights to exercise the Option accrue periodically, to the extent of a pro rata portion through the date of Disability of any additional vesting rights that
would have accrued on the next vesting date had the Participant not become Disabled. The proration shall be based upon the number of days accrued in the current vesting period prior to the date of Disability. 


A Disabled Participant may exercise such rights only within the period ending one year after the date of the Participant’s
termination of employment, directorship or consultancy, as the case may be, notwithstanding that the Participant might have been able to exercise the Option as to some or all of the Shares on a later date if the Participant had not become Disabled
and had continued to be an Employee, Director or Consultant or, if earlier, within the originally prescribed term of the Option. 

The Committee shall make the determination both of whether Disability has occurred and the date of its occurrence (unless a procedure for
such determination is set forth in another agreement between the Company and such Participant, in which case such procedure shall be used for such determination). If requested, the Participant shall be examined by a physician selected or approved by
the Committee, the cost of which examination shall be paid for by the Company. 
  

	13.	EFFECT OF DEATH WHILE AN EMPLOYEE, DIRECTOR OR CONSULTANT. 


Except as otherwise provided in a Participant’s Option Agreement, in the event of the death of a Participant while the Participant is
an Employee, Director or Consultant of the Company or of an Affiliate, such Option may be exercised by the Participant’s Survivors: 
  

	 	a.	To the extent that the Option has become exercisable but has not been exercised on the date of death; and 


 

	 	b.	In the event rights to exercise the Option accrue periodically, to the extent of a pro rata portion through the date of death of any additional vesting rights that
would have accrued on the next vesting date had the Participant not died. The proration shall be based upon the number of days accrued in the current vesting period prior to the Participant’s date of death. 


If the Participant’s Survivors wish to exercise the Option, they must take all necessary steps to exercise the Option within one
year after the date of death of such Participant, notwithstanding that the decedent might have been able to exercise the Option as to some or all of the Shares on a later date if he or she had not died and had continued to be an Employee, Director
or Consultant or, if earlier, within the originally prescribed term of the Option. 
  

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	14.	DISSOLUTION OR LIQUIDATION OF THE COMPANY. 


Upon the dissolution or liquidation of the Company, all Options granted under this Plan which as of such date shall not have been
exercised will terminate and become null and void; provided, however, that if the rights of a Participant or a Participant’s Survivors have not otherwise terminated and expired, the Participant or the Participant’s Survivors will have the
right immediately prior to such dissolution or liquidation to exercise any Option to the extent that the Option is exercisable as of the date immediately prior to such dissolution or liquidation. 

 

	15.	ADJUSTMENTS. 

 Upon the
occurrence of any of the following events, a Participant’s rights with respect to any Option granted to him or her hereunder which has not previously been exercised in full shall be adjusted as hereinafter provided, unless otherwise
specifically provided in the Participant’s Option Agreement: 
 A. Stock Dividends and Stock Splits. If (i) the
shares of Common Stock shall be subdivided or combined into a greater or smaller number of shares or if the Company shall issue any shares of Common Stock as a stock dividend on its outstanding Common Stock, or (ii) additional shares or new or
different shares or other securities of the Company or other non-cash assets are distributed with respect to such shares of Common Stock, the number of shares of Common Stock deliverable upon the exercise of such Option may be appropriately
increased or decreased proportionately, and appropriate adjustments may be made including, in the purchase price per share, to reflect such events. 

B. Corporate Transactions. If the Company is to be consolidated with or acquired by another entity in a merger, sale of all or
substantially all of the Company’s assets other than a transaction to merely change the state of incorporation (a “Corporate Transaction”), or in the event of a Change in Control, the Committee or the board of directors of any entity
assuming the obligations of the Company hereunder (the “Successor Board”), shall, as to outstanding Options, either (i) make appropriate provision for the continuation of such Options by substituting on an equitable basis for the
Shares then subject to such Options either the consideration payable with respect to the outstanding shares of Common Stock in connection with the Corporate Transaction or securities of any successor or acquiring entity; or (ii) upon written
notice to the Participants, provide that all Options must be exercised (either to the extent then exercisable or, at the discretion of the Committee or, upon a Change in Control, all Options being made fully exercisable for purposes of this
Subparagraph), within a specified number of days of the date of such notice (or, if shorter, during their remaining term), at the end of which period the Options shall terminate; or (iii) terminate all Options in exchange for a cash payment
equal to the excess of the Fair Market Value of the Shares subject to such Options (either to the extent then exercisable or, at the discretion of the Committee, all Options being made fully exercisable for purposes of this Subparagraph) over the
exercise price thereof. 
 C. Recapitalization or Reorganization. In the event of a recapitalization or reorganization of
the Company other than a Corporate Transaction pursuant to which securities of the Company or of another corporation are issued with respect to the outstanding shares of 

 

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Common Stock, a Participant upon exercising an Option after the recapitalization or reorganization shall be entitled to receive for the purchase price paid upon such exercise the number of
replacement securities which would have been received if such Option had been exercised prior to such recapitalization or reorganization. 

D. Modification of ISOs. Notwithstanding the foregoing, any adjustments made pursuant to Subparagraph A, B or C above with respect
to ISOs shall be made only after the Committee determines whether such adjustments would constitute a “modification” of such ISOs (as that term is defined in Section 424(h) of the Code) or would cause any adverse tax consequences for
the holders of such ISOs. If the Committee determines that such adjustments made with respect to ISOs would constitute a modification of such ISOs, it may refrain from making such adjustments, unless the holder of an ISO specifically requests in
writing that such adjustment be made and such writing indicates that the holder has full knowledge of the consequences of such “modification” on his or her income tax treatment with respect to the ISO. 

 

	16.	ISSUANCES OF SECURITIES. 


Except as expressly provided herein, no issuance by the Company of shares of stock of any class, or securities convertible into shares of
stock of any class, shall affect, and no adjustment by reason thereof shall be made with respect to, the number or price of shares subject to Options. Except as expressly provided herein, no adjustments shall be made for dividends paid in cash or in
property (including without limitation, securities) of the Company. 
  

	17.	FRACTIONAL SHARES. 

 No
fractional shares shall be issued under the Plan and the person exercising such right shall receive from the Company cash in lieu of such fractional shares equal to the Fair Market Value thereof. 

 

	18.	CONVERSION OF ISOs INTO NON-QUALIFIED OPTIONS; TERMINATION OF ISOs. 


The Committee, at the written request of any Participant, may in its discretion take such actions as may be necessary to convert such
Participant’s ISOs (or any portions thereof) that have not been exercised on the date of conversion into Non-Qualified Options at any time prior to the expiration of such ISOs, regardless of whether the Participant is an employee of the Company
or an Affiliate at the time of such conversion. At the time of such conversion, the Committee (with the consent of the Participant) may impose such conditions on the exercise of the resulting Non-Qualified Options as the Committee in its discretion
may determine, provided that such conditions shall not be inconsistent with this Plan. Nothing in the Plan shall be deemed to give any Participant the right to have such Participant’s ISOs converted into Non-Qualified Options, and no such
conversion shall occur until and unless the Committee takes appropriate action. The Committee, with the consent of the Participant, may also terminate any portion of any ISO that has not been exercised at the time of such conversion. 

 

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	19.	WITHHOLDING. 

 In the
event that any federal, state, or local income taxes, employment taxes, Federal Insurance Contributions Act (“F.I.C.A.”) withholdings or other amounts are required by applicable law or governmental regulation to be withheld from the
Participant’s salary, wages or other remuneration in connection with the exercise of an Option or a Disqualifying Disposition (as defined in Paragraph 20), the Company may withhold from the Participant’s compensation, if any, or may
require that the Participant advance in cash to the Company, or to any Affiliate of the Company which employs or employed the Participant, the statutory minimum amount of such withholdings unless a different withholding arrangement, including the
use of shares of the Company’s Common Stock, is authorized by the Committee (and permitted by law). For purposes hereof, the Fair Market Value of the shares withheld for purposes of payroll withholding shall be determined in the manner provided
in Paragraph 1 above, as of the most recent practicable date prior to the date of exercise. If the Fair Market Value of the shares withheld is less than the amount of payroll withholdings required, the Participant may be required to advance the
difference in cash to the Company or the Affiliate employer. 
  

	20.	NOTICE TO COMPANY OF DISQUALIFYING DISPOSITION. 


Each Employee who receives an ISO must agree to notify the Company in writing immediately after the Employee makes a Disqualifying
Disposition of any shares acquired pursuant to the exercise of an ISO. A Disqualifying Disposition is defined in Section 424(c) of the Code and includes any disposition (including any sale or gift) of such shares before the later of
(a) two years after the date the Employee was granted the ISO, or (b) one year after the date the Employee acquired Shares by exercising the ISO, except as otherwise provided in Section 424(c) of the Code. If the Employee has died
before such stock is sold, these holding period requirements do not apply and no Disqualifying Disposition can occur thereafter. 
  

	21.	TERMINATION OF THE PLAN. 


The Plan will terminate on 10 years after adoption, the date which is ten years from the earlier of the date of its adoption by the
Board of Directors and the date of its approval by the shareholders. The Plan may be terminated at an earlier date by vote of the shareholders or the Board of Directors of the Company; provided, however, that any such earlier termination shall not
affect any Option Agreements executed prior to the effective date of such termination. 
  

	22.	AMENDMENT, MODIFICATION, TERMINATION AND TAX COMPLIANCE. 


A. Amendment, Modification, and Termination: Subject to the terms of the Plan, the Committee or the Board of Directors may at any
time and from time to time, alter, amend, suspend, or terminate the Plan in whole or in part or alter or amend any outstanding Options or Option Agreements. 

B. Options Previously Granted: Notwithstanding any other provision of the Plan to the contrary, no termination, amendment, or
modification of the Plan or any amendment of any outstanding Options or Option Agreements shall adversely affect in any material way any Option 

 

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previously granted under the Plan, without the written consent of the Participant holding such Option; provided that no consent is required for any amendment the Committee deems necessary or
appropriate to comply with applicable legal or tax requirements, including to the extent necessary to qualify the shares issuable upon exercise of any outstanding Options granted, or Options to be granted, under the Plan for listing on any national
securities exchange. 
 C. Shareholder Approval Required for Certain Amendments: Shareholder approval will be required
for any amendment of the Plan that does any of the following: (a) permits the grant of any Option with an exercise price less than the Fair Market Value of the Shares on the date of grant; or (b) reduces the exercise price of an
outstanding Option, either by lowering the exercise price or by canceling an outstanding Option and granting a replacement Option with a lower exercise price. 

D. Compliance with Section 409A: It is intended that Options granted under this Plan are exempt from Section 409A. The
Plan shall be administered and interpreted in accordance with that intent. By way of example, the following rules shall apply: 
  

	 	a.	Any adjustment or modification to an Option shall be made in compliance with Section 409A (e.g., any adjustment to an Option under Paragraph 15 shall be
made in accordance with the requirements of Section 409A); 

  

	 	b.	The determination of the Fair Market Value of a Share for purposes of establishing the exercise price of an Option shall be made in accordance with the requirements of
Section 409A; and 

  

	 	c.	Any right to amend, terminate or modify the Plan or any outstanding Option or Option Agreement is subject to the requirements and limitations of Section 409A.


 While the Company intends for Options to be exempt from Section 409A, neither the Company nor the Committee shall be
liable to any person for the tax consequences of any failure to comply with the requirements of Section 409A or any other tax consequences relating to Options under this Plan. 

 

	23.	EMPLOYMENT OR OTHER RELATIONSHIP. 


Nothing in this Plan or any Option Agreement shall be deemed to prevent the Company or an Affiliate from terminating the employment,
consultancy or director status of a Participant, nor to prevent a Participant from terminating his or her own employment, consultancy or director status or to give any Participant a right to be retained in employment or other service by the Company
or any Affiliate for any period of time. 
  

	24.	SUCCESSORS. 

 All
obligations of the Company under the Plan with respect to Options granted hereunder shall be binding on any successor to the Company, whether the existence of such successor is the result of a direct or indirect purchase, merger, consolidation, or
otherwise, of all or substantially all of the business, stock and/or assets of the Company. 
  

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	25.	GENERAL PROVISIONS. 

 A.
Gender and Number: Except where otherwise indicated by the context, any masculine term used herein also shall include the feminine; the plural shall include the singular and the singular shall include the plural. 

B. Severability: If any provision of the Plan shall be held illegal or invalid for any reason, the illegality or invalidity shall
not affect the remaining parts of the Plan, and the Plan shall be construed and enforced as if the illegal or invalid provision had not been included. 

C. Requirements of Law: The granting of Options and the issuance of Shares under the Plan shall be subject to all applicable laws,
rules, and regulations, and to such approvals by any governmental agencies or national securities exchanges as may be required. 

D. Securities Law Compliance: With respect to Insiders, transactions under this Plan are intended to comply with all applicable
conditions of Rule 16b-3 or its successors under the Exchange Act, unless determined otherwise by the Board of Directors. To the extent any provision of the Plan or action by the Committee fails to so comply, it shall be deemed null and void, to the
extent permitted by law and deemed advisable by the Board of Directors. 
 E. Listing: The Company may use reasonable
endeavors to register Shares allotted pursuant to the exercise of an Option with the United States Securities and Exchange Commission or to effect compliance with the registration, qualification, and listing requirements of any national securities
laws or stock exchange. 
 F. Inability to Obtain Authority: The inability of the Company to obtain authority from any
regulatory body having jurisdiction, which authority is deemed by the Company’s counsel to be necessary to the lawful issuance and sale of any Shares hereunder, shall relieve the Company of any liability in respect of the failure to issue or
sell such Shares as to which such requisite authority shall not have been obtained. 
 G. No Additional Rights: Neither
the grant of Options nor any benefits arising under this Plan shall constitute part of an employment contract between the Participant and the Company or any Affiliate, and accordingly, this Plan and the benefits hereunder may be terminated at any
time in the sole and exclusive discretion of the Board of Directors without giving rise to liability on the part of the Company or any Affiliate for severance payments. 

H. Uncertificated Shares: To the extent that the Plan provides for issuance of certificates to reflect the transfer of Shares, the
transfer of such Shares may be effected on a noncertificated basis, to the extent not prohibited by applicable law or the rules of any stock exchange. 

I. Governing Law: The Plan and each Option Agreement shall be governed by the laws of the State of Maryland, excluding any
conflicts or choice of law rule or principle that might otherwise refer construction or interpretation of the Plan to the substantive law of another 

 

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jurisdiction. Unless otherwise provided in the Option Agreement, recipients of an Option under the Plan are deemed to submit to the exclusive jurisdiction and venue of the federal or state courts
located in the State of Maryland, County of Prince Georges, to resolve any and all issues that may arise out of or relate to the Plan or any related Option Agreement. 

 

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