2

Mecoprop-p (MCPP-p) Preliminary Work Plan – Table of Contents 

OVERVIEW ................................................................................................................................... 4

ANTICIPATED DATA NEEDS .................................................................................................... 5

STATUTORY AND REGULATORY AUTHORITY ................................................................... 5

CHEMICAL FACTS ...................................................................................................................... 6

USE AND USAGE INFORMATION ............................................................................................ 6

RECENT ACTIONS ....................................................................................................................... 8

ANTICIPATED RISK ASSESSMENTS FOR REGISTRATION REVIEW ................................ 8

TIMELINE .................................................................................................................................... 10

NEXT STEPS ............................................................................................................................... 10

Appendix – Additional Areas Considered in the MCPP-p Registration Review ..................... 11 

References:

This Preliminary Work Plan summarizes the Environmental Protection Agency's current position 

based on the following documents: 

1. Problem Formulation for the Environmental Fate and Ecological Risk, Endangered 

Species, and Drinking Water Assessments in Support of the Registration Review of 

Mecoprop-p (MCPP-p). Carey, Steve and Adbel-Saheb, Ibrahim. June 2, 2014. 

2. MCPP, MCPP-p (Acid), MCPP-p DMAS, and MCPP-p potassium salt Human Health 

Assessment Scoping Document in Support of Registration Review. Tadayon, Seyed, 

Taylor, Linda, and Savoia, Peter. February 28, 2014. 

3. MCPP (Mecoprop): Tier I Review of Human Incidents. Recore, Shanna, and Evans, 

Elizabeth. February 4, 2014. 

4. BEAD Chemical Profile (BCP) for Registration Review of Mecoprop Chemical Case [Includes 

Mecoprop (031501); Mecoprop-potassium (031503); Mecoprop dimethylamine salt (031519); 

MCPP-P, DMA salt (031520); Mecoprop-P potassium (1 19046); and MCPP-p (129046)].

Hill, Elizabeth, Prieto, Rafael, and Yourman, Leonard. May 23, 2014. 
3

5. Mecoprop (MCPP) Screening Level Usage Analysis. May 8, 2013 

6. Environmental Fate and Effects Division Spreadsheet: PC Codes: 031402, 031403, 

031416, 031464, and 031465. May 5, 2014.

7. Health Effects Division Master Label Spreadsheet: PC Codes: 031402, 031403, 031416, 

031464, and 031465. May 5, 2014.

These and other supporting documents for the MCPP-p registration review case may be found in 

the docket EPA-HQ-OPP- EPA-HQ-OPP-2014-0361 at http://www.regulations.gov. 
4

OVERVIEW 

The docket for the MCPP-p case is now open, initiating the first public comment period for this 

registration review (docket number EPA-HQ-OPP-2014-0361). This case includes the following 

active ingredients: mecoprop-p acid (MCPP-p), MCPP-p dimethylamine salt (MCPP-p DMAS), 

and MCPP-p potassium salt. The PC codes included in this case are: 129046, 031520, and 

119046. These compounds are collectively referred to as MCPP-p. Products containing racemic 

mecoprop (MCPP) and its salts have been reformulated to the enriched isomer formulation 

MCPP-p. Therefore, registration review will focus solely on MCPP-p and its salts. MCPP-p is a 

non-selective herbicide in the chlorophenoxy class of herbicides that is registered for nonagricultural use to control a variety of weeds on commercial and residential lawns; turfgrass; golf 

courses; sod farms; and outdoor residential areas. It is registered for noxious weed and brush 

control use on uncultivated, non-agricultural areas such as rights-of-way, roadsides, and airports. 

There are no registered food or feed uses, and MCPP-p products are used primarily in residential, 

commercial, institutional, and industrial areas. This Preliminary Work Plan (PWP) document 

explains what EPA's Office of Pesticide Programs knows about MCPP-p, highlighting 

anticipated data and assessment needs, identifying the types of information that would be 

especially useful to the Agency in conducting the review, and providing an anticipated timeline 

for completing the registration review for MCPP-p. 

 

The registration review process was designed to include a public participation component to 

solicit input from interested stakeholders. The Agency intends, by sharing this information in the 

docket, to inform the public of what it knows about MCPP-p and what types of new data or other 

information would be helpful for the Agency to receive as it moves toward a decision on MCPPp. The Agency encourages all interested stakeholders to review the PWP and Appendix and to 

provide comments and additional information that will help the Agency’s decision-making 

process for this chemical. In addition to general areas on which persons may wish to comment, 

there are some areas identified in the PWP and Appendix about which the Agency specifically 

seeks comments and information. Interested stakeholders could include: environmental nonprofit or interest groups; pesticide manufacturers; agricultural labor or commodity groups; 

commercial, institutional, residential, and other users of pesticides; or the public at large. 

The Preliminary Work Plan begins by listing the anticipated data needs for MCPP-p. Next, it 

discusses the statutory and regulatory authority for Registration Review. Then the document 

provides chemical facts, use and usage information, recent actions, the anticipated risk 

assessments, and a projected registration review timeline for MCPP-p. Finally, the Appendix to 

this document includes identification and discussion of some areas that are considered generally 

in Registration Review along with some additional chemical case-specific information. 

 
5

ANTICIPATED DATA NEEDS 

Table 1 below summarizes anticipated data needs for MCPP-p. For additional discussion of the 

anticipated data needs, see the Problem Formulation for the Environmental Fate and Ecological 

Risk, Endangered Species, and Drinking Water Assessments in Support of the Registration 

Review of Mecoprop-p (MCPP-p) and MCPP, MCPP-p (Acid), MCPP-p DMAS, and MCPP-p 

potassium salt Human Health Assessment Scoping Document in Support of Registration Review.

Table 1: Anticipated Data Needs for the MCPP-p Registration Review 

Guideline 

Number1 Study Title1 

Test Material2

Estimated 

Timeframe 

(Months from 

receipt of DCI) 

850.2100 Avian oral toxicity (passerine species) TGAI 12 

850.2300 Avian reproduction (waterfowl species) TGAI 24 

870.34653 90-day inhalation toxicity TGAI 12 

NONGDLN Pollinator Acute Oral Toxicity (honeybee larvae) TGAI 12 

NONGDLN Pollinator Acute Oral Toxicity (honeybee adult) TGAI 12 

NONGDLN Pollinator Chronic Oral Toxicity (honeybee 

adult) TGAI 12 

TGAI = technical grade active ingredient; 

STATUTORY AND REGULATORY AUTHORITY 

The Food Quality Protection Act (FQPA) of 1996 mandated a registration review program. All 

pesticides distributed or sold in the United States (U.S.) generally must be registered by the 

Environmental Protection Agency (EPA or the Agency), based on scientific data showing that 

they will not cause unreasonable risks to human health or the environment when used as directed 

on product labeling. The registration review program is intended to make sure that, as the ability 

to assess risk evolves and as policies and practices change, all registered pesticides continue to 

meet the statutory standard of no unreasonable adverse effects to human health or the 

environment. Changes in science, public policy, and pesticide use practices will occur over time. 

Through the registration review program, the Agency periodically reevaluates pesticides to make 

sure that as change occurs, products in the marketplace can be used safely. Information on this 

program is provided on EPA’s website.4

 

1

 On June 27, 2012, EPA announced certain revisions in harmonized guideline series 850 – Ecological Effects Tests 

– including renumbering and other designations or changes for some guideline studies. See “Final Test 

Guidelines; OCSPP 850 Series; Notice of Availability” 77 FR 38282, June 27, 2012. 

http://www.regulations.gov/#!documentDetail;D=EPA-HQ-OPPT-2009-0154-0028 2

 Data are anticipated to be required on either the acid or DMAS formulation. 

3

 For the inhalation toxicity study, an acceptable test of 28 days duration would be expected to be sufficient to 

satisfy this anticipated data requirement. 

4

 http://www.epa.gov/oppsrrd1/registration_review/ 
6

The Agency is implementing the registration review program pursuant to Section 3(g) of the 

Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), and will review each registered 

pesticide every 15 years to determine whether it continues to meet the FIFRA standard for 

registration. The regulations governing registration review begin at 40 CFR 155.40. The 

Agency will consider benefits information and data as required by FIFRA. The public phase of 

registration review begins when the initial docket is opened for each case. The docket is the 

Agency’s opportunity to state what it knows about the pesticide and what additional risk analyses 

and data or information it believes are needed to make a registration review decision. After 

reviewing and responding to comments and data received in the docket during this initial 

comment period, the Agency will develop a Final Work Plan (FWP) and anticipated schedule for 

the registration review of MCPP-p. 

CHEMICAL FACTS 

Table 2 provides a summary of the chemical facts for MCPP-p. 

Table 2: Chemical Facts for MCPP-p

PC code 031520, 119046, and 129046 

Case Number 0377 

CAS Number 66423-09-4, 16484-77-8, 66423-05-0 

Year first registered MCPP:1968; MCPP-p:1996 

Pesticide Type Chlorophenoxy herbicide 

Chemical class Not applicable. 

Reregistration Eligibility 

Decision (RED) 

2007 

Tolerance Reassessment 

Eligibility Decision 

(TRED) 

Not applicable. There are no food or feed uses of MCPP-p. 

Cumulative group Not applicable. MCPP-p has not been identified as a member of a 

cumulative group that shares a common mechanism of toxicity. 

40 CFR Citation There are no established tolerances for MCPP-p. 

Dual-use MCPP-p is registered for conventional pesticidal uses only and 

has no registered antimicrobial or biopesticidal uses. 

Non-pesticidal uses There are no identified non-pesticidal uses of MCPP-p. 

Pesticide Re-evaluation 

Division, Chemical 

Review Manager 

Kaitlin Keller, keller.kaitlin@epa.gov, (703) 308-8172 

Registration Division, 

Product Manager 

Kathryn Montague, montague.kathryn@epa.gov, (703) 305-1243 

USE AND USAGE INFORMATION 

Table 3 summarizes the use and usage information for MCPP-p. Please see the BEAD Chemical 

Profile (BCP) for Registration Review of Mecoprop Chemical Case in the registration review 

docket for more details. 
7

Table 3: MCPP-p Use and Usage Information

Summary of Use MCPP-p is a non-selective chlorophenoxy herbicide registered for 

post-emergent use to control broadleaf and noxious weeds and 

brush in non-agricultural residential, commercial, and industrial 

areas such as rights-of-way, roadsides, golf courses, sod farms, 

and residential and commercial lawns. MCPP-p products are 

commonly co-formulated with other herbicides as ready-to-use 

turfgrass products. MCPP-p is not currently registered for food or 

agricultural uses. 

Use Sites Non-agricultural use sites include commercial/industrial areas, 

turfgrass (commercial/industrial, residential, recreational, golf 

course, sod farms), uncultivated areas, fencerows/hedgerows, 

rights-of-way, paths/patios, recreational areas, airport landing 

fields, and grasses grown for seed. 

Summary of Usage EPA has very limited usage data for MCPP-p due to its nonagricultural and diffuse types of use patterns. The vast majority 

of MCPP-p use is primarily for residential lawns, with smaller 

uses for commercial turf, such as for golf courses. From 2004-

20012, a relatively small amount of MCPP-p was reported on 

pasture/rangelands; however, it has not been reported since 2007. 

In 2012, approximately 800,000 pounds of MCPP-p formulations 

were used on turf and ornamentals.

Formulation Type(s) Granules, pressurized liquids, ready-to-use liquids, soluble 

liquids, wettable powders, pressurized liquids, flowable 

concentrates, emulsifiable concentrates, and liquid soluble 

concentrates. 

Application Method(s) Products can be applied by granular spreaders, 

handheld/backpack sprayers, ground sprayers, trigger spray 

bottles, mechanical sprays, and aerosol cans. 

Technical Registrant(s) Nufarm Americas, Inc. and PBI/Gordon Corp. 

No. of Registrations 278 Section 3 products5

Restricted Use No 

Guidance for Commenters: Additional areas of use and usage related information

requested for this registration review, and of particular interest to EPA, are described below. 

 Certain MCPP-p labels are unclear with respect to application parameters such as the size 

of the treated area, the extent of a treated “spot,” retreatment intervals, or maximum 

annual application rates. Without further information, EPA expects to use conservative 

assumptions to approximate these parameters in order to conduct a quantitative risk 

assessment. However, the Agency will work with registrants to clarify information on 

MCPP-p product labels, especially the maximum annual application rates for nonagricultural uses including golf courses, turf, ornamentals, and residential lawns. 

 

5

 Section 3 product labels can be obtained from the Pesticide Product Label System (PPLS) website 

(http://oaspub.epa.gov/pestlabl/ppls.home). 
8

 Confirmation of the following label information: sites of application; formulations; 

application methods and equipment; maximum application rates; frequency of 

application, application intervals, and maximum number of applications per season; and 

geographic limitations on use. 

 Use distribution (e.g., acreage and geographical distribution of relevant use sites). 

 Median and 90th percentile reported use rates (lbs ai/A) from usage data – national, state, 

and county. 

 Typical application timing (date of first application and application intervals) – national, 

state, and county. 

 Usage/use information for non-agricultural uses (total pounds active ingredient applied 

annually on residential, ornamental, turf, rights-of-way, and pastureland). 

 Percent crop/site treated. 

 Application rates: typical and maximum. 

 Frequency of application. 

 Typical application interval (days). 

 Methods of application. 

 Target or niche pests. 

 Efficacy information/product performance. 

 State or local use restrictions. 

 Foreign technical registrants not listed above who supply technical MCPP-p to the US 

market. 

RECENT ACTIONS 

There are no recent actions for MCPP-p. 

ANTICIPATED RISK ASSESSMENTS FOR REGISTRATION REVIEW 

The most recent comprehensive human health risk assessment for MCPP-p was completed on 

July 26, 2007 in preparation for the 2007 Reregistration Eligibility Decision. The most recent 

ecological and environmental fate risk assessment was completed August 28, 2007 for the same 

purpose. Findings and conclusions from these risk assessments are summarized in the Problem 

Formulation for the Environmental Fate and Ecological Risk, Endangered Species, and 

Drinking Water Assessments in Support of the Registration Review of Mecoprop-p (MCPP-p)

and MCPP, MCPP-p (Acid), MCPP-p DMAS, and MCPP-p potassium salt Human Health 

Assessment Scoping Document in Support of Registration Review.

During registration review, the Agency anticipates the need to conduct a comprehensive 

ecological risk assessment, including an endangered species assessment, for all uses of MCPP-p. 

For human health, EPA anticipates the need to conduct revised dietary (drinking water only), 

residential, and occupational risk assessments during registration review. If toxicological 

endpoints or points of departure are revised based on the data that are anticipated to be required 

for registration review, they will be considered in the new assessments, as well as any changes to 

the standard operating procedures or default exposure assumptions. 

Table 4 below summarizes the anticipated registration review risk assessments based on the 

EFED Problem Formulation and HED Scoping Document. 
9

Table 4: Anticipated Risk Assessments for the MCPP-p Registration Review 

Type of Risk Assessment Conduct? Notes 

Ecological and Environmental Fate 

Comprehensive ecological 

(species to be assessed 

include terrestrial and aquatic 

organisms), including 

endangered species 

Y 

Incidents Will check for 

updates 

For a discussion of reported ecological incidents for 

MCPP-p, see page 16 and Appendix B of the Problem 

Formulation. 

Human Health 

Dietary 

Food N MCPP-p is not currently registered for use on food or 

feed. 

Drinking water Y Updated dietary (drinking water only) risk 

assessments may be needed during registration review 

to consider newly estimated drinking water 

concentrations and/or changes in the toxicological 

endpoints. 

Occupational 

Handlers (mixers, loaders, 

applicators) 

Y Updated occupational exposure assessments may be 

needed during registration review to consider new 

exposure estimates based on current science policies 

or if there are changes in the toxicological endpoints. 

Post-application N There is no evidence of systemic toxicity from dermal 

exposure. Appropriate re-entry intervals (REIs) are 

currently on product labels, thus significant dermal 

exposure from recently treated areas is not 

anticipated. 

Residential 

Handlers Y Updated residential exposure assessments may be 

needed during registration review to consider new 

exposure estimates based on current science policies 

or if there are changes in the toxicological endpoints. 

Post-application Y 

Other 

Aggregate Y Evaluates the combined risk from dietary (drinking 

water only) and residential exposures. 

Cumulative N MCPP-p has not been identified as a member of a 

cumulative group that shares a common mechanism 

of toxicity. 

Tolerances N Tolerances are not established for MCPP-p since it is 

not registered for use on food or feed at this time. 
10

Incidents Will check for 

updates 

For a discussion of reported human incidents for 

MCPP-p, see page 9 of the Scoping Document and 

the MCPP (Mecoprop): Tier 1 Review of Human 

Incidents. 

Guidance for Commenters: Additional ecological information requested for this registration 

review, and of particular interest to EPA, is described below. 

 Ecological incidents (non-target plant damage and avian, fish, reptilian, amphibian and 

mammalian mortalities) not already reported to the Agency. 

 Water quality monitoring data (see Appendix for further details). 

TIMELINE 

EPA has created the following estimated timeline for the completion of the MCPP-p registration 

review in Table 5 below. 

Table 5: Projected MCPP-p Registration Review Timeline

Activities Estimated Date

Opening the Docket 

Open Docket and 60-day Public Comment Period 2014 – June 

Close Public Comment 2014 – August 

Case Development 

Final Work Plan 2014 – November 

Issue DCI 2015 – Jan.- March 

Data Submission 2017 – Jan.- March 

60-day Public Comment Period for Draft Risk 

Assessments6

2018 – July - Sept. 

Registration Review Decision 

60-day Public Comment Period for Proposed 

Registration Review Decision 

2019 – April - June 

Registration Review Decision and Begin Post-Decision 

Follow-up 

2020 

Total (years) 6 

NEXT STEPS 

After the 60-day public comment period closes, the Agency will review and respond to any 

comments received in a timely manner and then issue a Final Work Plan for the registration 

review of MCPP-p. 

 

6

 The regulations governing Registration Review generally require the Agency to provide a public comment period 

of at least 30 calendar days for draft risk assessments; see 40 CFR Part 155.53(c). For conventional pesticides, the 

Agency plans to provide a 60 calendar day public comment period generally for draft risk assessments. 
11

Appendix – Additional Areas Considered in the MCPP-p Registration Review 

PUBLIC COMMENTS AND FEEDBACK: 

Guidance for Commenters: The areas below highlight topics of special interest to the Agency 

where your comments, data submissions, or reference to sources of additional information could 

be of particular use.

Trade Irritants: 

Through the registration review process, the Agency intends to solicit information on trade 

irritants and, to the extent feasible, take steps toward facilitating irritant resolution. The Agency 

will work to harmonize tolerances and international maximum residue limits (MRLs) and may 

modify tolerance levels to do so, when possible. Growers and other stakeholders are asked to 

comment on any trade irritant issues resulting from lack of MRLs or disparities between U.S. 

tolerances and MRLs in key export markets, providing as much specificity as possible regarding 

the nature of the concern. Because MCPP-p is not registered for food/feed uses in the U.S., it 

has no U.S. tolerances; therefore, the Agency does not anticipate any trade irritant issues for it. 

Water Quality: 

MCPP-p is not identified as a cause of impairment for any water bodies listed as impaired under 

section 303(d) of the Clean Water Act.7 In addition, no Total Maximum Daily Loads (TMDL) 

have been developed for MCPP-p.8 More information on impaired water bodies and TMDLs can 

be found at the Agency’s website.9 The Agency invites submission of water quality data for 

this pesticide. To the extent possible, submissions should include the key data elements noted in 

the OPP Guidance for Submission of State and Tribal Water Quality Monitoring Data 10 in order 

to ensure they can be used quantitatively or qualitatively in pesticide risk assessments. 

Environmental Justice: 

EPA seeks to achieve environmental justice, the fair treatment and meaningful involvement of all 

people, regardless of race, color, national origin, or income, in the development, implementation, 

and enforcement of environmental laws, regulations, and policies. To help address potential 

environmental justice issues, the Agency seeks information on any groups or segments of the 

population who, as a result of their location, cultural practices, or other factors, may have 

atypical, unusually high exposure to MCPP-p compared to the general population. Please 

comment if you are aware of any sub-populations that may have atypical, unusually high 

exposure compared to the general population.

 

7 http://iaspub.epa.gov/tmdl_waters10/attains_nation_cy.cause_detail_303d?p_cause_group_id=885

8

http://iaspub.epa.gov/tmdl_waters10/attains_nation.tmdl_pollutant_detail?p_pollutant_group_id=885&p_pollutant_

group_name=PESTICIDES 9 http://www.epa.gov/owow/tmdl/

10 http://www.epa.gov/oppsrrd1/registration_review/water_quality_sop.htm
12

ENDANGERED SPECIES: 

A risk assessment that supports a complete endangered species determination has not been 

conducted for MCPP-p. The ecological risk assessment planned during registration review will 

allow the Agency to determine whether use of MCPP-p has “no effect” or “may affect” federally 

listed threatened or endangered species (listed species) or their designated critical habitats. 

When an assessment concludes that a pesticide’s use “may affect” a listed species or its 

designated critical habitat, the Agency will consult with the U.S. Fish and Wildlife Service 

and/or National Marine Fisheries Service (the Services), as appropriate. 

ENDOCRINE DISRUPTOR SCREENING PROGRAM: 

As required by FIFRA and FFDCA, EPA reviews numerous studies to assess potential adverse 

outcomes from exposure to chemicals. Collectively, these studies include acute, subchronic and 

chronic toxicity, including assessments of carcinogenicity, neurotoxicity, developmental, 

reproductive, and general or systemic toxicity. These studies include endpoints which may be 

susceptible to endocrine influence, including effects on endocrine target organ histopathology, 

organ weights, estrus cyclicity, sexual maturation, fertility, pregnancy rates, reproductive loss, 

and sex ratios in offspring. For ecological hazard assessments, EPA evaluates acute tests and 

chronic studies that assess growth, developmental and reproductive effects in different 

taxonomic groups. As part of its reregistration decision for MCPP-p, EPA reviewed these data 

and selected the most sensitive endpoints for relevant risk assessment scenarios from the existing 

hazard database. However, as required by FFDCA section 408(p), MCPP-p is subject to the 

endocrine screening part of the Endocrine Disruptor Screening Program (EDSP). 

EPA has developed the EDSP to determine whether certain substances (including pesticide 

active and other ingredients) may have an effect in humans or wildlife similar to an effect 

produced by a “naturally occurring estrogen, or other such endocrine effects as the Administrator 

may designate.” The EDSP employs a two-tiered approach to making the statutorily required 

determinations. Tier 1 consists of a battery of 11 screening assays to identify the potential of a 

chemical substance to interact with the estrogen, androgen, or thyroid (E, A, or T) hormonal 

systems. Chemicals that go through Tier 1 screening and are found to have the potential to 

interact with E, A, or T hormonal systems will proceed to the next stage of the EDSP where EPA 

will determine which, if any, of the Tier 2 tests are necessary based on the available data. Tier 2 

testing is designed to identify any adverse endocrine-related effects caused by the substance, and 

establish a dose-response relationship between the dose and the E, A, or T effect. 

Under FFDCA section 408(p), the Agency must screen all pesticide chemicals. Between 

October 2009 and February 2010, EPA issued test orders/data call-ins for the first group of 67 

chemicals, which contains 58 pesticide active ingredients and 9 inert ingredients. A second list 

of chemicals identified for EDSP screening was published on June 14, 201311 and includes some 

pesticides scheduled for registration review and chemicals found in water. Neither of these lists 

should be construed as a list of known or likely endocrine disruptors. 

 

11 See http://www.regulations.gov/#!documentDetail;D=EPA-HQ-OPPT-2009-0477-0074 for the final second list of 

chemicals. 
13

For further information on the status of the EDSP, the policies and procedures, the lists of 

chemicals, future lists, the test guidelines and the Tier 1 screening battery, please visit our 

website.12

HUMAN STUDIES: 

Occupational and Residential 

Past MCPP-p risk assessments rely in part on data from studies in which adult human subjects 

were intentionally exposed to a pesticide to determine their dermal and inhalation exposure. 

Many such studies, involving exposure to many different pesticides, comprise generic pesticide 

exposure databases such as the Pesticide Handlers Exposure Database (PHED), the Agricultural 

Reentry Task Force (ARTF) Database, and the Outdoor Residential Exposure Task Force 

(ORETF) Database. EPA has reviewed all the studies supporting these multi-pesticide generic 

exposure databases, and has found no clear and convincing evidence that the conduct of any of 

them was either fundamentally unethical or significantly deficient relative to the ethical 

standards prevailing at the time the research was conducted. All applicable requirements of 

EPA’s Rule for the Protection of Human Subjects of Research (40 CFR Part 26) have been 

satisfied, and there is no regulatory barrier to continued reliance on these studies. 

 

12 http://www.epa.gov/endo/