11562 Federal Register / Vol. 77, No. 38 / Monday, February 27, 2012 / Notices 

Potential Commercial Applications 

• Therapeutic potential for treating 

general and drug-resistant bacterial 

infections in clinical and veterinary 

populations. 

• Antiseptics in hospital settings. 

Competitive Advantages 

• Effective for commonly occurring 

drug-resistant infections MRSA and 

VRE. 

• Broad spectrum of efficacy because 

mechanism of action is against the 

bacterial protein FtsZ, which has similar 

structure in all bacteria. 

• Potential for additive efficacy when 

combined with other antibiotics due to 

distinct mechanism of action. 

• Other drugs with similar structure 

and antibacterial properties can be 

synthesized using the chemical 

structure template shown above. 

Development Stage 

• Early-stage. 

• In vitro data available. 

Inventors: Carole A Bewley, et al. 

(NIDDK). 

Publication: Plaza A, et al. 

Chrysophaentins A–H, antibacterial 

bisdiarylbutene macrocycles that inhibit 

the bacterial cell division protein FtsZ. 

J Am Chem Soc. 2010 Jul 

7;132(26):9069–9077. [PMID 20536175]. 

Intellectual Property: HHS Reference 

No. E–116–2010/0—PCT Application 

No. PCT/US2011/026200 filed 25 Feb 

2011, which published as WO 2011/ 

106630 on 01 Sep 2011. 

Licensing Contact: John Stansberry, 

Ph.D.; 301–435–5236; 

stansbej@mail.nih.gov. 

Collaborative Research Opportunity: 

The National Institute of Diabetes and 

Digestive and Kidney Diseases, 

Laboratory of Bioorganic Chemistry, is 

seeking statements of capability or 

interest from parties interested in 

collaborative research to further 

develop, evaluate, or commercialize the 

chrysophaentin antibiotics. Please 

contact Marguerite J. Miller at 301–451– 

3636 or millermarg@niddk.nih.gov for 

more information. 

Dated: February 21, 2012. 

Richard U. Rodriguez, 

Director, Division of Technology Development 

and Transfer, Office of Technology Transfer, 

National Institutes of Health. 

[FR Doc. 2012–4376 Filed 2–24–12; 8:45 am] 

BILLING CODE 4140–01–P 

DEPARTMENT OF HEALTH AND 

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National Institute of General Medical 

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Meeting. 

The meeting will be closed to the 

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Name of Committee: National Institute of 

General Medical Sciences Special Emphasis 

Panel Review of Minority Biomedical 

Research Support Genetics Applications. 

Date: March 19–20, 2012. 

Time: 8:30 a.m. to 5 p.m. 

Agenda: To review and evaluate grant 

applications. 

Place: Hyatt Regency—Bethesda, One 

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Contact Person: Saraswathy Seetharam, 

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Scientific Review, National Institute of 

General Medical Sciences, National Institutes 

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seetharams@nigms.nih.gov. 

(Catalogue of Federal Domestic Assistance 

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Research Support; 93.821, Cell Biology and 

Biophysics Research; 93.859, Pharmacology, 

Physiology, and Biological Chemistry 

Research; 93.862, Genetics and 

Developmental Biology Research; 93.88, 

Minority Access to Research Careers; 93.96, 

Special Minority Initiatives, National 

Institutes of Health, HHS) 

Dated: February 21, 2012. 

Jennifer S. Spaeth, 

Director, Office of Federal Advisory 

Committee Policy. 

[FR Doc. 2012–4526 Filed 2–24–12; 8:45 am] 

BILLING CODE 4140–01–P 

DEPARTMENT OF HEALTH AND 

HUMAN SERVICES 

National Institutes of Health 

National Institute on Deafness and 

Other Communication Disorders; 

Notice of Closed Meeting 

Pursuant to section 10(d) of the 

Federal Advisory Committee Act, as 

amended (5 U.S.C. App.), notice is 

hereby given of the following meeting. 

The meeting will be closed to the 

public in accordance with the 

provisions set forth in sections 

552b(c)(4) and 552b(c)(6), Title 5 

U.S.C., as amended. The grant 

applications and the discussions could 

disclose confidential trade secrets or 

commercial property such as patentable 

material, and personal information 

concerning individuals associated with 

the grant applications, the disclosure of 

which would constitute a clearly 

unwarranted invasion of personal 

privacy. 

Name of Committee: National Institute on 

Deafness and Other Communication 

Disorders Special Emphasis Panel P30 

Review 

Date: March 28, 2012. 

Time: 12:30 p.m. to 3:30 p.m. 

Agenda: To review and evaluate grant 

applications. 

Place: National Institutes of Health, 6120 

Executive Blvd., Rockville, MD 20852 

(Telephone Conference Call). 

Contact Person: Christine A. Livingston, 

Ph.D. Scientific Review Officer, Division of 

Extramural Activities, National Institutes of 

Health/NIDCD, 6120 Executive Blvd.—MSC 

7180, Bethesda, MD 20892, (301) 496–8683, 

livingsc@mail.nih.gov. 

Information is also available on the 

Institute’s/Center’s home page: http:// 

www.nidcd.nih.gov/about/groups/sep/, 

where an agenda and any additional 

information for the meeting will be posted 

when available. 

(Catalogue of Federal Domestic Assistance 

Program Nos. 93.173, Biological Research 

Related to Deafness and Communicative 

Disorders, National Institutes of Health, HHS) 

Dated: February 21, 2012. 

Jennifer S. Spaeth, 

Director, Office of Federal Advisory 

Committee Policy. 

[FR Doc. 2012–4535 Filed 2–24–12; 8:45 am] 

BILLING CODE 4140–01–P 

DEPARTMENT OF HEALTH AND 

HUMAN SERVICES 

National Institutes of Health 

National Institute of General Medical 

Sciences; Notice of Closed Meeting 

Pursuant to section 10(d) of the 

Federal Advisory Committee Act, as 


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