Exhibit 10.2(b)

[***] Certain information in this document has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been
requested with respect to the omitted portions.

WORK ORDER #1

PROTOCOL NUMBER: CHS-1420-02

This Work Order #1 is made and entered as of the 31st day of March, 2015 (the Effective Date) by and between Coherus
BioSciences, Inc. (Sponsor) and Worldwide Clinical Trials, Inc. (WCT).

WHEREAS, Sponsor and WCT
have entered into that certain Master Services Agreement dated February 27, 2015 (hereinafter referred to as the Agreement); and

WHEREAS, pursuant to the Agreement, WCT has agreed to perform certain Services in accordance with Work Orders from time to time entered
into by the Parties, as more fully provided in Section 1.0 of the Master Agreement, and Sponsor and WCT now desire to enter into such a Work Order, (the Work Order).

WHEREAS, WCT and Sponsor desire that WCT provide certain Services with respect to CHS-1420-02: A Double-Blind, Randomized,
Parallel-Group, Active-Control Study to Compare the Efficacy and Safety of CHS-1420 DP Versus Humira® in Subjects with Chronic Plaque Psoriasis (PsO), (the Study) for the
study of the drug CHS-1420 (Study Drug).

NOW, THEREFORE, in consideration of the mutual covenants contained
herein, the Parties hereby agree as follows:

1. Scope of Services. WCT shall perform the Services described in the Scope of
Services, attached to this Work Order as Attachment A (Scope of Services).

2. Compensation. For performance of
these Services, Sponsor shall pay to WCT the amounts set forth in the Budget set forth in Attachment B to this Work Order, which amounts shall be payable pursuant to the Payment Schedule set forth in Attachment C to this Work Order.

3. Term and Termination. The term of this Work Order shall commence upon the Effective Date stated above and shall continue until
completion of Services as described in Attachment A, provided, however, the provisions of the Agreement shall govern its termination prior to completion.

4. Incorporation by Reference; Conflict. The provisions of the Agreement are hereby expressly incorporated by reference into and made a
part of this Work Order. In the event of a conflict between the terms and conditions of this Work Order and those of the Agreement, the terms of the Agreement shall take precedence and control over those of this Work Order unless the Work Order
expressly and specifically states an intent to supersede the Agreement on a specific matter by reference. Unless otherwise specifically defined herein, each term used herein which is defined in the Agreement shall have the meaning assigned to such
term in the Agreement.

5. Timely Completion. The timeline for this Work Order is attached as Attachment D.

6. Currency. All invoices and amounts to be paid shall be in USD.

7. Additional Indemnification. The parties agree that Sponsor further agrees to indemnify, defend, and hold harmless Service Provider,
its Affiliates and their respective officers, directors, employees, agents and other representatives against any and all claims, expenses or losses (including reasonable attorneys fees) as a result of [***].



1



---

IN WITNESS WHEREOF, the Parties have hereunto signed this Work Order effective as of the
Effective Date.



|                                |  |                           |  |  |  |        |  |                         |  | 
|------------------------------- |  | ------------------------- |  |  |  | ------ |  | ----------------------- |  | 
|Worldwide Clinical Trials, Inc. |  | Coherus BioSciences, Inc. |  | 
|                                |  |                           |  |  | 
|By:                             |  | /s/ Emily Hales           |  |  |  | By:    |  | /s/ Jean-Frederic Viret |  | 
|                                |  |                           |  |  | 
|Name:                           |  | Emily Hales               |  |  |  | Name:  |  | Jean-Frederic Viret     |  | 
|                                |  |                           |  |  | 
|Title:                          |  | Authorized Signatory      |  |  |  | Title: |  | Chief Financial Officer |  | 
|                                |  |                           |  |  | 
|Date:                           |  | April 1, 2015             |  |  |  | Date:  |  | April 10, 2015          |  | 

LIST OF ATTACHMENTS:



|              |  |  |  |                  
|------------- |  |  |  | -----------------
|ATTACHMENT A: |  |  |  | SCOPE OF SERVICES
|ATTACHMENT B: |  |  |  | BUDGET           
|ATTACHMENT C: |  |  |  | PAYMENT SCHEDULE 
|ATTACHMENT D: |  |  |  | TIMELINE         



[***] Certain information in this
document has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been requested with respect to the omitted portions.



2



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WORK ORDER #1

ATTACHMENT A

SCOPE OF
SERVICES



|                                    |  |                   |   |     
|----------------------------------- |  | ----------------- | - | ----
|Cost Driver                         |  | WCTs Assumptions |  
|Countries, Sites, Patients and CRAs | 
|[***]                               |  |                   | [ | ***]
|[***]                               |  |                   | [ | ***]
|[***]                               |  |                   | [ | ***]
|[***]                               |  |                   | [ | ***]
|[***]                               |  |                   | [ | ***]
|[***]                               |  |                   | [ | ***]
|[***]                               |  |                   | [ | ***]
|[***]                               |  |                   | [ | ***]
|[***]                               |  |                   | [ | ***]
|[***]                               |  |                   | [ | ***]
|[***]                               |  |                   | [ | ***]
|[***]                               |  |                   | [ | ***]
|[***]                               |  |                   | [ | ***]
|[***]                               |  |                   | [ | ***]
|[***]                               |  |                   | [ | ***]
|[***]                               |  |                   | [ | ***]
|                                    | 
|[***]                               |  |                   | [ | ***]
|                                    | 
|[***]                               |  |                   | [ | ***]
|[***]                               |  |                   | [ | ***]
|[***]                               |  |                   | [ | ***]
|[***]                               |  |                   | [ | ***]
|[***]                               |  |                   | [ | ***]
|[***]                               |  |                   | [ | ***]
|[***]                               |  |                   | [ | ***]
|[***]                               |  |                   | [ | ***]
|[***]                               |  |                   | [ | ***]
|[***]                               |  |                   | [ | ***]
|[***]                               |  |                   | [ | ***]
|                                    | 
|[***]                               |  |                   | [ | ***]
|                                    | 
|[***]                               |  |                   | [ | ***]
|[***]                               |  |                   | [ | ***]
|[***]                               |  |                   | [ | ***]
|[***]                               |  |                   | [ | ***]
|[***]                               |  |                   | [ | ***]
|[***]                               |  |                   | [ | ***]
|[***]                               |  |                   | [ | ***]
|Back-up Sites                       | 
|[***]                               |  |                   | [ | ***]



[***] Certain information in this
document has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been requested with respect to the omitted portions.



3



---

|                   |  |  |   |     
|------------------ |  |  | - | ----
|[***]              |  |  | [ | ***]
|[***]              |  |  | [ | ***]
|[***]              |  |  | [ | ***]
|[***]              |  |  | [ | ***]
|[***]              |  |  | [ | ***]
|[***]              |  |  | [ | ***]
|[***]              |  |  | [ | ***]
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|[***]              |  |  | [ | ***]
|[***]              |  |  | [ | ***]
|[***]              |  |  | [ | ***]
|[***]              |  |  | [ | ***]
|[***]              |  |  | [ | ***]
|[***]              |  |  | [ | ***]
|Study Duration     | 
|[***]              |  |  | [ | ***]
|[***]              |  |  | [ | ***]
|[***]              |  |  | [ | ***]
|[***]              |  |  | [ | ***]
|Project Management | 
|[***]              |  |  | [ | ***]
|[***]              |  |  | [ | ***]
|[***]              |  |  | [ | ***]
|[***]              |  |  | [ | ***]
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|[***]              |  |  | [ | ***]
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|[***]              |  |  | [ | ***]
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|[***]              |  |  | [ | ***]
|[***]              |  |  | [ | ***]
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|[***]              |  |  | [ | ***]
|[***]              |  |  | [ | ***]
|[***]              |  |  | [ | ***]
|[***]              |  |  | [ | ***]
|[***]              |  |  | [ | ***]



[***] Certain information in this
document has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been requested with respect to the omitted portions.



4



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|                                  |  |  |   |     
|--------------------------------- |  |  | - | ----
|[***]                             |  |  | [ | ***]
|[***]                             |  |  | [ | ***]
|Investigator Meeting              | 
|[***]                             |  |  | [ | ***]
|[***]                             |  |  | [ | ***]
|[***]                             |  |  | [ | ***]
|[***]                             |  |  | [ | ***]
|[***]                             |  |  | [ | ***]
|[***]                             |  |  | [ | ***]
|[***]                             |  |  | [ | ***]
|[***]                             |  |  | [ | ***]
|Communication                     | 
|[***]                             |  |  | [ | ***]
|[***]                             |  |  | [ | ***]
|[***]                             |  |  | [ | ***]
|[***]                             |  |  | [ | ***]
|[***]                             |  |  | [ | ***]
|[***]                             |  |  | [ | ***]
|[***]                             |  |  | [ | ***]
|[***]                             |  |  | [ | ***]
|Regulatory and Ethics Submissions | 
|[***]                             |  |  | [ | ***]
|[***]                             |  |  | [ | ***]
|[***]                             |  |  | [ | ***]
|[***]                             |  |  | [ | ***]
|[***]                             |  |  | [ | ***]
|[***]                             |  |  | [ | ***]
|[***]                             |  |  | [ | ***]
|[***]                             |  |  | [ | ***]
|[***]                             |  |  | [ | ***]
|[***]                             |  |  | [ | ***]
|[***]                             |  |  | [ | ***]
|[***]                             |  |  | [ | ***]
|[***]                             |  |  | [ | ***]
|[***]                             |  |  | [ | ***]
|[***]                             |  |  | [ | ***]
|[***]                             |  |  | [ | ***]
|[***]                             |  |  | [ | ***]
|[***]                             |  |  | [ | ***]
|[***]                             |  |  | [ | ***]
|[***]                             |  |  | [ | ***]
|[***]                             |  |  | [ | ***]
|[***]                             |  |  | [ | ***]
|[***]                             |  |  | [ | ***]



[***] Certain information in this
document has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been requested with respect to the omitted portions.



5



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|                    |  |  |   |     
|------------------- |  |  | - | ----
|[***]               |  |  | [ | ***]
|Start-up Activities | 
|[***]               |  |  | [ | ***]
|[***]               |  |  | [ | ***]
|[***]               |  |  | [ | ***]
|[***]               |  |  | [ | ***]
|[***]               |  |  | [ | ***]
|[***]               |  |  | [ | ***]
|                    | 
|[***]               |  |  | [ | ***]
|                    | 
|[***]               |  |  | [ | ***]
|[***]               |  |  | [ | ***]
|[***]               |  |  | [ | ***]
|[***]               |  |  | [ | ***]
|[***]               |  |  | [ | ***]
|[***]               |  |  | [ | ***]
|[***]               |  |  | [ | ***]
|[***]               |  |  | [ | ***]
|[***]               |  |  | [ | ***]
|[***]               |  |  | [ | ***]
|[***]               |  |  | [ | ***]
|[***]               |  |  | [ | ***]
|[***]               |  |  | [ | ***]
|[***]               |  |  | [ | ***]
|[***]               |  |  | [ | ***]
|[***]               |  |  | [ | ***]
|[***]               |  |  | [ | ***]
|[***]               |  |  | [ | ***]
|Study Initiation    | 
|[***]               |  |  | [ | ***]
|[***]               |  |  | [ | ***]
|[***]               |  |  | [ | ***]
|[***]               |  |  | [ | ***]
|[***]               |  |  | [ | ***]
|[***]               |  |  | [ | ***]
|[***]               |  |  | [ | ***]
|[***]               |  |  | [ | ***]
|[***]               |  |  | [ | ***]
|[***]               |  |  | [ | ***]
|[***]               |  |  | [ | ***]
|[***]               |  |  | [ | ***]
|[***]               |  |  | [ | ***]
|[***]               |  |  | [ | ***]
|[***]               |  |  | [ | ***]
|[***]               |  |  | [ | ***]



[***] Certain information in this
document has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been requested with respect to the omitted portions.



6



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|              |  |  |   |     
|------------- |  |  | - | ----
|[***]         |  |  | [ | ***]
|[***]         |  |  | [ | ***]
|[***]         |  |  | [ | ***]
|[***]         |  |  | [ | ***]
|Study Conduct |  |  |   |     
|[***]         |  |  | [ | ***]
|[***]         |  |  | [ | ***]
|[***]         |  |  | [ | ***]
|[***]         |  |  | [ | ***]
|[***]         |  |  | [ | ***]
|[***]         |  |  | [ | ***]
|[***]         |  |  | [ | ***]
|[***]
[***]   |  |  |   |     
|[***]         |  |  |   |     
|[***]         |  |  | [ | ***]
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|[***]         |  |  | [ | ***]
|[***]         |  |  | [ | ***]
|[***]         |  |  | [ | ***]
|[***]         |  |  | [ | ***]
|[***]         |  |  | [ | ***]
|[***]         |  |  | [ | ***]
|[***]         |  |  | [ | ***]
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|[***]         |  |  | [ | ***]
|[***]         |  |  | [ | ***]
|[***]         |  |  | [ | ***]
|[***]         |  |  | [ | ***]
|[***]         |  |  | [ | ***]



[***] Certain information in this
document has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been requested with respect to the omitted portions.



7



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|                                    |  |  |   |     
|----------------------------------- |  |  | - | ----
|[***]                               |  |  | [ | ***]
|Drug Safety / Pharmacovigilance     | 
|[***]                               |  |  | [ | ***]
|[***]                               |  |  | [ | ***]
|[***]
[***]
[***]
[***]
[***]
[***] |  |  |   |     
|                                    | 
|[***]                               |  |  | [ | ***]
|                                    | 
|[***]                               |  |  |   |     
|                                    | 
|[***]                               |  |  | [ | ***]
|                                    | 
|[***]                               |  |  | [ | ***]
|[***]                               |  |  | [ | ***]
|[***]                               |  |  | [ | ***]
|[***]                               |  |  | [ | ***]
|[***]                               |  |  | [ | ***]
|[***]                               |  |  | [ | ***]
|[***]                               |  |  | [ | ***]
|[***]                               |  |  | [ | ***]
|[***]                               |  |  | [ | ***]
|[***]                               |  |  | [ | ***]
|[***]                               |  |  | [ | ***]
|[***]                               |  |  | [ | ***]
|[***]                               |  |  | [ | ***]
|[***]                               |  |  | [ | ***]
|[***]                               |  |  | [ | ***]
|[***]                               |  |  | [ | ***]
|[***]                               |  |  | [ | ***]
|[***]                               |  |  | [ | ***]
|Drug Safety Monitoring Board (DSMB) |  |  |   |     
|[***]                               |  |  | [ | ***]
|[***]                               |  |  | [ | ***]
|[***]                               |  |  | [ | ***]
|[***]                               |  |  | [ | ***]
|[***]                               |  |  | [ | ***]
|Medical Monitoring                  |  |  |   |     



[***] Certain information in this
document has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been requested with respect to the omitted portions.



8



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|                              |  |  |   |     
|----------------------------- |  |  | - | ----
|[***]                         |  |  | [ | ***]
|                              | 
|[***]
[***]
[***]
[***]
[***] |  |  |   |     
|                              | 
|[***]                         |  |  | [ | ***]
|                              | 
|[***]
[***]                   |  |  |   |     
|[***]                         |  |  | [ | ***]
|[***]                         |  |  |   |     
|[***]                         |  |  | [ | ***]
|Data Management               |  |  |   |     
|[***]                         |  |  | [ | ***]
|[***]                         |  |  | [ | ***]
|[***]                         |  |  | [ | ***]
|[***]                         |  |  | [ | ***]
|[***]                         |  |  | [ | ***]
|[***]                         |  |  | [ | ***]
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|[***]                         |  |  | [ | ***]
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|[***]                         |  |  | [ | ***]
|[***]                         |  |  | [ | ***]
|[***]                         |  |  | [ | ***]
|[***]                         |  |  | [ | ***]
|[***]                         |  |  | [ | ***]
|Statistics                    |  |  |   |     
|[***]                         |  |  | [ | ***]
|[***]                         |  |  | [ | ***]



[***] Certain information in this
document has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been requested with respect to the omitted portions.



9



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|                |  |  |   |     
|--------------- |  |  | - | ----
|[***]           |  |  | [ | ***]
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|[***]           |  |  |   |     
|[***]           |  |  | [ | ***]
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|[***]           |  |  | [ | ***]
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|[***]           |  |  | [ | ***]
|[***]
[***]     |  |  |   |     
|[***]           |  |  | [ | ***]
|Medical Writing |  |  |   |     



[***] Certain information in this
document has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been requested with respect to the omitted portions.



10



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|                                                      |  |  |          |                         
|----------------------------------------------------- |  |  | -------- | ------------------------
|[***]                                                 |  |  | [        | ***]                    
|[***]                                                 |  |  | [        | ***]                    
|[***]                                                 |  |  | [        | ***]                    
|[***]
[***]
[***]                                     |  |  |          |                         
|[***]                                                 |  |  | [        | ***]                    
|[***]                                                 |  |  | [        | ***]                    
|[***]                                                 |  |  | [        | ***]                    
|[***]                                                 |  |  | [        | ***]                    
|[***]                                                 |  |  | [        | ***]                    
|Clinical Assessment and Training                      |  |  |          |                         
|[***]                                                 |  |  | [        | ***]                    
|[***]                                                 |  |  | [[
[ [
[ | ***] ***]
***] ***]
***]
|IxRS                                                  |  |  |          |                         
|[***]                                                 |  |  | [        | ***]                    
|[***]                                                 |  |  | [        | ***]                    
|[***]                                                 |  |  | [        | ***]                    
|[***]                                                 |  |  | [        | ***]                    
|                                                      | 
|[***]
[***]
[***]                                     |  |  |          |                         
|                                                      | 
|[***]                                                 |  |  | [        | ***]                    
|[***]
[***]
[***]
[***]
[***]
[***]
[***]
[***]
[***] |  |  |          |                         
|[***]                                                 |  |  | [        | ***]                    
|[***]
[***]
[***]                                     |  |  |          |                         
|[***]                                                 |  |  | [        | ***]                    



[***] Certain information in this
document has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been requested with respect to the omitted portions.



11



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|                                    |  |  |   |     
|----------------------------------- |  |  | - | ----
|[***]                               |  |  | [ | ***]
|[***]
[***]
[***]
[***]
[***]
[***] |  |  |   |     
|[***]                               |  |  | [ | ***]
|[***]
[***]
[***]
[***]
[***]       |  |  |   |     
|[***]                               |  |  | [ | ***]
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|[***]                               |  |  | [ | ***]
|[***]                               |  |  | [ | ***]
|[***]                               |  |  | [ | ***]
|[***]                               |  |  | [ | ***]
|[***]                               |  |  |   |     
|[***]                               |  |  | [ | ***]
|                                    | 
|[***]                               |  |  |   |     
|                                    | 
|[***]                               |  |  | [ | ***]
|[***]                               |  |  | [ | ***]
|Clinical Trials Materials Handling  |  |  |   |     
|[***]                               |  |  | [ | ***]
|[***]                               |  |  | [ | ***]
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|[***]
[***]
[***]                   |  |  |   |     
|[***]                               |  |  | [ | ***]
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|[***]                               |  |  | [ | ***]
|[***]                               |  |  | [ | ***]
|[***]                               |  |  | [ | ***]



[***] Certain information in this
document has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been requested with respect to the omitted portions.



12



---

|      |  |  |   |     
|----- |  |  | - | ----
|[***] |  |  | [ | ***]
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|[***] |  |  | [ | ***]
|[***] |  |  | [ | ***]
|[***] |  |  | [ | ***]



[***] Certain information in this
document has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been requested with respect to the omitted portions.



13



---

WORK ORDER #1

ATTACHMENT B

BUDGET



|                                 |  |                                                                                                                                                                                                |  |         |  |                 |  |                |  |      
|-------------------------------- |  | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- |  | ------- |  | --------------- |  | -------------- |  | -----
|Worldwide Clinical Trials Budget |  |                                                                                                                                                                                                |  |         |  |                 |  |               
|                                 |  |                                                                                                                                                                                                |  |         | 
|Client:                          |  |                                                                                                                                                                                                |  | Coherus |  |                 |  |                |  |      
|                                 | 
|Study:                           |  | CHS-1420-02: A Double-Blind, Randomized, Parallel-Group, Active-Control
Study to Compare the Efficacy and Safety of CHS-1420 DP Versus Humira® in Subjects with Chronic Plaque Psoriasis (PsO)
|Services                         |  | Unit                                                                                                                                                                                           |  | # Units |  | Unit Cost USD $ |  | WCT Fees USD $
|                                 |  |                                                                                                                                                                                                |  |        
|Clinical Start Up                |  |                                                                                                                                                                                                |  |         |  |                 |  |               
|                                 |  |                                                                                                                                                                                                |  |         | 
|o                                |  | [***]                                                                                                                                                                                          |  | [***]   |  | [***]           |  | [***]          |  | [***]
|                                 |  |                                                                                                                                                                                                |  |         | 
|o                                |  | [***]                                                                                                                                                                                          |  | [***]   |  | [***]           |  | [***]          |  | [***]
|                                 |  |                                                                                                                                                                                                |  |         | 
|o                                |  | [***]                                                                                                                                                                                          |  | [***]   |  | [***]           |  | [***]          |  | [***]
|                                 |  |                                                                                                                                                                                                |  |         | 
|o                                |  | [***]                                                                                                                                                                                          |  | [***]   |  | [***]           |  | [***]          |  | [***]
|                                 |  |                                                                                                                                                                                                |  |         | 
|o                                |  | [***]                                                                                                                                                                                          |  | [***]   |  | [***]           |  | [***]          |  | [***]
|                                 |  |                                                                                                                                                                                                |  |         | 
|o                                |  | [***]                                                                                                                                                                                          |  | [***]   |  | [***]           |  | [***]          |  | [***]
|                                 |  |                                                                                                                                                                                                |  |         | 
|o                                |  | [***]                                                                                                                                                                                          |  | [***]   |  | [***]           |  | [***]          |  | [***]
|                                 |  |                                                                                                                                                                                                |  |         | 
|o                                |  | [***]                                                                                                                                                                                          |  | [***]   |  | [***]           |  | [***]          |  | [***]
|                                 |  |                                                                                                                                                                                                |  |         | 
|o                                |  | [***]                                                                                                                                                                                          |  | [***]   |  | [***]           |  | [***]          |  | [***]
|                                 |  |                                                                                                                                                                                                |  |         | 
|o                                |  | [***]                                                                                                                                                                                          |  | [***]   |  | [***]           |  | [***]          |  | [***]
|                                 |  |                                                                                                                                                                                                |  |         | 
|o                                |  | [***]                                                                                                                                                                                          |  | [***]   |  | [***]           |  | [***]          |  | [***]
|                                 |  |                                                                                                                                                                                                |  |         | 
|o                                |  | [***]                                                                                                                                                                                          |  | [***]   |  | [***]           |  | [***]          |  | [***]
|                                 |  |                                                                                                                                                                                                |  |         | 
|o                                |  | [***]                                                                                                                                                                                          |  | [***]   |  | [***]           |  | [***]          |  | [***]
|                                 |  |                                                                                                                                                                                                |  |         | 
|o                                |  | [***]                                                                                                                                                                                          |  | [***]   |  | [***]           |  | [***]          |  | [***]
|                                 |  |                                                                                                                                                                                                |  |         | 
|o                                |  | [***]                                                                                                                                                                                          |  | [***]   |  | [***]           |  | [***]          |  | [***]
|                                 |  |                                                                                                                                                                                                |  |         | 
|o                                |  | [***]                                                                                                                                                                                          |  | [***]   |  | [***]           |  | [***]          |  | [***]
|                                 |  |                                                                                                                                                                                                |  |         | 
|o                                |  | [***]                                                                                                                                                                                          |  |         |  |                 |  |                |  |      
|                                 |  |                                                                                                                                                                                                |  |         | 
|                                 |  | [***]                                                                                                                                                                                          |  | [***]   |  | [***]           |  | [***]          |  | [***]
|                                 |  |                                                                                                                                                                                                |  |         | 
|                                 |  | [***]                                                                                                                                                                                          |  | [***]   |  | [***]           |  | [***]          |  | [***]
|                                 |  |                                                                                                                                                                                                |  |         | 
|o                                |  | [***]                                                                                                                                                                                          |  | [***]   |  | [***]           |  | [***]          |  | [***]
|                                 |  |                                                                                                                                                                                                |  |         | 
|o                                |  | [***]                                                                                                                                                                                          |  | [***]   |  | [***]           |  | [***]          |  | [***]
|Sub-Total Study Start Up         |  |                                                                                                                                                                                                |  |         |  |                 |  | [***]         
|                                 |  |                                                                                                                                                                                                |  |        
|Regulatory Affairs               |  |                                                                                                                                                                                                |  |         |  |                 |  |               
|                                 |  |                                                                                                                                                                                                |  |         | 
|o                                |  | [***]                                                                                                                                                                                          |  | [***]   |  | [***]           |  | [***]          |  | [***]
|                                 |  |                                                                                                                                                                                                |  |         | 
|o                                |  | [***]                                                                                                                                                                                          |  | [***]   |  | [***]           |  | [***]          |  | [***]



[***] Certain information in this
document has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been requested with respect to the omitted portions.



14



---

|                                          |  |       |  |       |  |       |  |       |  |      
|----------------------------------------- |  | ----- |  | ----- |  | ----- |  | ----- |  | -----
|o                                         |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                         |  | [***] |  |       |  |       |  |       |  |      
|                                          |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|                                          |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                         |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                         |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                         |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                         |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                         |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                         |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                         |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                         |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                         |  | [***] |  |       |  |       |  |       |  |      
|                                          |  | Full  |  | [***] |  | [***] |  | [***] |  | [***]
|Sub-Total Regulatory Affairs              |  |       |  |       |  |       |  | [***]
|Trial Master File                         |  |       |  |       |  |      
|o                                         |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                         |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                         |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|Sub-Total Trial Master File               |  |       |  |       |  |       |  | [***]
|Communication                             |  |       |  |       |  |      
|o                                         |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                         |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                         |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                         |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                         |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                         |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                         |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|Sub-Total Communication                   |  |       |  |       |  |       |  | [***]
|Vendor Contracting & Management           |  |       |  |       |  |      
|o                                         |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                         |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                         |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                         |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                         |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|Sub-Total Vendor Contracting & Management |  |       |  |       |  |       |  | [***]



[***] Certain information in this
document has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been requested with respect to the omitted portions.



15



---

|                              |  |       |  |       |  |       |  |       |  |      
|----------------------------- |  | ----- |  | ----- |  | ----- |  | ----- |  | -----
|Clinical Monitoring           |  |       |  |       |  |      
|o                             |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                             |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                             |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                             |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                             |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                             |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                             |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                             |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                             |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|Sub Total Clinical Monitoring |  |       |  |       |  |       |  | [***]
|Grant Payments                |  |       |  |       |  |      
|o                             |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                             |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                             |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                             |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                             |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|Sub-Total Grant Payments      |  |       |  |       |  |       |  | [***]
|Drug Safety Services          |  |       |  |       |  |      
|o                             |  | [***] |  |       |  |       |  |       |  |      
|                              |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|                              |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|                              |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|                              |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                             |  | [***] |  |       |  |       |  |       |  |      
|                              |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|                              |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                             |  | [***] |  |       |  |       |  |       |  |      
|                              |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|                              |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|                              |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|                              |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|                              |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|                              |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|                              |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|                              |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]



[***] Certain information in this
document has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been requested with respect to the omitted portions.



16



---

|                                    |  |       |  |       |  |       |  |       |  |      
|----------------------------------- |  | ----- |  | ----- |  | ----- |  | ----- |  | -----
|o                                   |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|Sub-Total Safety                    |  |       |  |       |  |       |  | [***]
|Drug Safety Monitoring Board (DSMB) |  |       |  |       |  |      
|o                                   |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                   |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|Sub-Total DSMB                      |  |       |  |       |  |       |  | [***]
|Medical Monitoring                  |  |       |  |       |  |      
|o                                   |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                   |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|Sub-Total Medical Monitoring        |  |       |  |       |  |       |  | [***]
|Data Management                     |  |       |  |       |  |      
|o                                   |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                   |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                   |  | [***] |  |       |  |       |  |       |  |      
|                                    |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|                                    |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|                                    |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                   |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                   |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                   |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                   |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                   |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                   |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                   |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                   |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                   |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                   |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                   |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                   |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|Sub-Total Data Management           |  |       |  |       |  |       |  | [***]
|Biostatistics                       |  |       |  |       |  |      
|o                                   |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                   |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                   |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                   |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                   |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]



[***] Certain information in this
document has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been requested with respect to the omitted portions.



17



---

|                        |  |       |  |       |  |       |  |       |  |      
|----------------------- |  | ----- |  | ----- |  | ----- |  | ----- |  | -----
|o                       |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                       |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                       |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                       |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                       |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                       |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                       |  | [***] |  |       |  |       |  |       |  |      
|                        |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|                        |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|                        |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|                        |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|                        |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                       |  | [***] |  |       |  |       |  |       |  |      
|                        |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|                        |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|                        |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|                        |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|                        |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                       |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                       |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                       |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                       |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                       |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                       |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                       |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                       |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                       |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                       |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                       |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                       |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                       |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|Sub-Total Biostatistics |  |       |  |       |  |       |  | [***]
|Clinical Writing        |  |       |  |       |  |      
|o                       |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                       |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                       |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]



[***] Certain information in this
document has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been requested with respect to the omitted portions.



18



---

|                                           |  |       |  |       |  |       |  |       |  |      
|------------------------------------------ |  | ----- |  | ----- |  | ----- |  | ----- |  | -----
|Sub-Total Clinical Writing                 |  |       |  |       |  |       |  | [***]
|Clinical Assessment and Training           |  |       |  |       |  |      
|o                                          |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|Sub-Total Clinical Assessment and Training |  |       |  |       |  |       |  | [***]
|Clinical Trial Materials Handling          |  |       |  |       |  |      
|o                                          |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                          |  | [***] |  |       |  |       |  |       |  |      
|                                           |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|                                           |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                          |  | [***] |  |       |  |       |  |       |  |      
|                                           |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|                                           |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|                                           |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|                                           |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|                                           |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|                                           |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                          |  | [***] |  |       |  |       |  |       |  |      
|                                           |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|                                           |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|                                           |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|                                           |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|                                           |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|                                           |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|                                           |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|                                           |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                          |  | [***] |  |       |  |       |  |       |  |      
|                                           |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]



[***] Certain information in this
document has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been requested with respect to the omitted portions.



19



---

|                                               |  |       |  |       |  |       |  |       |  |      
|---------------------------------------------- |  | ----- |  | ----- |  | ----- |  | ----- |  | -----
|o                                              |  | [***] |  |       |  |       |  |       |  |      
|                                               |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|                                               |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|                                               |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|Sub-Total Clinical Trials Materials Handling   |  |       |  |       |  |       |  | [***]
|IxRS                                           |  |       |  |       |  |      
|o                                              |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                              |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                              |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                              |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                              |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                              |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                              |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|Sub-Total IxRS                                 |  |       |  |       |  |       |  | [***]
|Technology                                     |  |       |  |       |  |      
|o                                              |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                              |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                              |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|Sub-Total Technology                           |  |       |  |       |  |       |  | [***]
|Project Management                             |  |       |  |       |  |      
|o                                              |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                              |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                              |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|Sub-Total Project Management                   |  |       |  |       |  |       |  | [***]
|Total Estimated Service Fees                   |  |       |  |       |  |       |  | [***]
|Estimated Pass-Through Costs                   |  |       |  |       |  |      
|Clinical Start-Up Pass-through Costs           |  |       |  |       |  |      
|o                                              |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                              |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                              |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|Sub-Total Clinical Start Up Pass-through Costs |  |       |  |       |  |       |  | [***]
|Regulatory Affairs Pass-through Costs          |  |       |  |       |  |      



[***] Certain information in this
document has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been requested with respect to the omitted portions.



20



---

|                                                    |  |       |  |       |  |       |  |       |  |      
|--------------------------------------------------- |  | ----- |  | ----- |  | ----- |  | ----- |  | -----
|o                                                   |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                                   |  | [***] |  |       |  |       |  |       |  |      
|                                                    |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|                                                    |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                                   |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                                   |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                                   |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                                   |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                                   |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                                   |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|Sub-Total Regulatory Affairs Pass-through Costs     |  |       |  |       |  |       |  | [***]
|Trial Master File Pass-through Costs                |  |       |  |       |  |      
|o                                                   |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|Sub-Total Trial Master File Pass-through Costs      |  |       |  |       |  |       |  | [***]
|Communication Pass-through Costs                    |  |       |  |       |  |      
|o                                                   |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                                   |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                                   |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|Sub-Total Communication Pass-through Costs          |  |       |  |       |  |       |  | [***]
|Study Conduct Pass-through Costs                    |  |       |  |       |  |      
|o                                                   |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                                   |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                                   |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                                   |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                                   |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                                   |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                                   |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                                   |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                                   |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|Sub Total Study Conduct Pass-through Costs          |  |       |  |       |  |       |  | [***]
|Clinical Assessment and Training Pass-through Costs |  |       |  |       |  |      
|o                                                   |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                                   |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                                   |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                                   |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]



[***] Certain information in this
document has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been requested with respect to the omitted portions.



21



---

|                                                                |  |       |  |       |  |       |  |       |  |      
|--------------------------------------------------------------- |  | ----- |  | ----- |  | ----- |  | ----- |  | -----
|o                                                               |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                                               |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                                               |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|Sub-Total Clinical Assessment and Training Pass-through Costs   |  |       |  |       |  | [***]
|Clinical Trial Materials Handling Pass-through Costs            |  |       |  |       |  |      
|o                                                               |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                                               |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                                               |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                                               |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                                               |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                                               |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                                               |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                                               |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                                               |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|Sub-Total Clinical Trials Materials Handling Pass-through Costs |  |       |  |       |  | [***]
|IxRS Pass-through Costs                                         |  |       |  |       |  |      
|o                                                               |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                                               |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                                               |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                                               |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|Sub-Total IxRS Pass-through Costs                               |  |       |  |       |  |       |  | [***]
|Archiving Pass-through Costs                                    |  |       |  |       |  |      
|o                                                               |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                                               |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                                               |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|Sub-Total Archiving Pass-through Costs                          |  |       |  |       |  |       |  | [***]
|Project Management Pass-through Costs                           |  |       |  |       |  |      
|o                                                               |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                                               |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                                               |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|Sub-Total Project Management Pass-through Costs                 |  |       |  |       |  |       |  | [***]



[***] Certain information in this
document has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been requested with respect to the omitted portions.



22



---

|                                   |  |       |  |       |  |       |  |       |  |      
|---------------------------------- |  | ----- |  | ----- |  | ----- |  | ----- |  | -----
|Third Party Vendor Costs           |  |       |  |       |  |      
|o                                  |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                  |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|Sub-Total Third Party Vendors      |  |       |  |       |  |       |  | [***]
|PI Fees                            |  |       |  |       |  |      
|o                                  |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                  |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|o                                  |  | [***] |  | [***] |  | [***] |  | [***] |  | [***]
|Sub-Total PI Fees                  |  |       |  |       |  |       |  | [***]
|Total Estimated Pass Through Costs |  |       |  |       |  | [***]
|Total Estimated Budget             |  |       |  |       |  | [***]



[***] Certain information in this
document has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been requested with respect to the omitted portions.



23



---

WORK ORDER #1

ATTACHMENT C

PAYMENT
SCHEDULE



|5. | Service Fees (To be billed separately):
|-- | ---------------------------------------



| | 5.1. | Notwithstanding the payment terms in Section 3.4 of the Agreement, [***] of this Work Order, Sponsor will [***] (Work Order [***]) which represents [***]. Work Order will be [***]. All subsequent invoices will be
submitted to Sponsor by email on a [***] basis for units completed in the previous [***], WCT will [***], until [***]. With the exception of [***], which shall be due within [***] days of Sponsors receipt of an invoice for same, payment terms
shall be as defined in the Agreement. Any outstanding balances will be reconciled at [***]. Service Fees shall be invoiced separately from Pass-through Expenses and Investigator/Institution Fees.
| | ---- | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | 5.2. | Bonus and Penalty fees: [Intentionally Omitted]
| | ---- | -----------------------------------------------



| | 5.3. | Payment shall be issued by [***]. Wiring instructions are as follows:
| | ---- | ---------------------------------------------------------------------



| |  |                   |  |  |  |                                
| |  | ----------------- |  |  |  | -------------------------------
| |  | Account Holder:   |  |  |  | Worldwide Clinical Trials, Inc.
| |  | Bank Name:        |  |  |  | [***]                          
| |  | Bank Address:     |  |  |  | [***]                          
| |  |                   |  |  |  | [***]                          
| |  | ABA Routing No.:  |  |  |  | [***]                          
| |  | Bank Account No.: |  |  |  | [***]                          
| |  | Swift Code:       |  |  |  | [***]                          
| |  | Taxpayer ID#:     |  |  |  | [***]                          



|6. | Pass-through Expenses (To be billed separately):
|-- | ------------------------------------------------



| | 6.1. | Notwithstanding the payment terms in Section 3.4 of the Agreement, [***] of this Work Order, Sponsor will [***] which is the [***], and [***] Pass-Through Expenses. Work Order will be [***].WCT will submit
subsequent [***] invoices by email for incurred Pass-through Expenses based on [***]. With each subsequent invoice for Pass-through Expenses, WCT will [***], until [***]. With the exception of [***], which shall be due within [***] days of
Sponsors receipt of an invoice for same, payment terms shall be as defined in the Agreement. Any outstanding balances will be reconciled at [***].
| | ---- | -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



|7. | Investigator/Institution Fees (To be billed separately):
|-- | --------------------------------------------------------



| | 7.1. | Notwithstanding the payment terms in Section 3.4 of the Agreement, [***] of this Work Order, Sponsor will [***] which represents [***]
| | ---- | --------------------------------------------------------------------------------------------------------------------------------------



[***] Certain information in this
document has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been requested with respect to the omitted portions.



24



---

| | [***]. Periodically, WCT will invoice Sponsor by email to [***]. The invoice will be accompanied by a report which [***]. If an increase in the amount of anticipated Investigator/Institution
grants is necessary, WCT will provide appropriate support justifying such increase. Any outstanding balances will be reconciled and provided [***]. For avoidance of doubt, WCT will make all grant payments only from funds received from Sponsor
specifically for this purpose. WCT shall not [***].
| | -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



|8. | Accounting close out for items 1, 2 and 3 above:
|-- | ------------------------------------------------



| | 8.1. | After [***] days following the end of the study, the presumption shall be that no further payments are owed by Sponsor to WCT for Service Fees. After [***] days following the end of the study, the presumption shall be
that no further payments will be made by Sponsor to WCT for Pass-through Expenses. Accordingly, Sponsor shall have a right to a refund of any amounts of the prepayments made in according to sections 1 through 3 above which exceed the aggregate
actual expense.
| | ---- | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



|9. | [***]:
|-- | ------

The parties shall negotiate in good faith a [***] as part of a change order.



[***] Certain information in this
document has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been requested with respect to the omitted portions.



25



---

WORK ORDER #1

ATTACHMENT D

TIMELINE



|                    |  |      
|------------------- |  | -----
|Assumptions Summary
|Milestone           |  | Date 
|[***]               |  | [***]
|[***]               |  | [***]
|[***]               |  | [***]
|[***]               |  | [***]
|[***]               |  | [***]
|[***]               |  | [***]
|[***]               |  | [***]
|[***]               |  | [***]
|[***]               |  | [***]
|[***]               |  | [***]



[***] Certain information in this
document has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been requested with respect to the omitted portions.



26