EPA Registration 264‐418

Vol.3
Material to be added to an e-Jacket/Jacket 

Reg. No. 

Description: \) \P- 't y r- I to 

1. D Placement within the e-JackeUjacket: 

WDefault: (chronological, top = newest) 

D File Location: (PDF page number, i.e., "before page 

45") 

2. D Send to Data Extraction contractors this material: 

D Newly stamped accepted label 

Er Notification 

D NewCSF 

D Other: ____________ _ 

3. Attach this coversheet to the top ofthe material or jacket. It 

must be well organized and clipped together, NOT STAPLED. 

Then give the material with this coversheet to staff in the 

Information Services Center (Room S-4900). 

Reviewer's Name: _-"U'="-----"'S'-'-c-<b-'-\.\)'-'-w-=--___ _ 

Phone: 3ij~ O~G6 Division: RO I Fe . 

Dale: ____ LA~~~¥~\~\--------------------__ -

Created August 19, 2008 

1

Material to be added to an e-Jacket/Jacket 

Reg. No. 

Description: \) \P- 't y r- I to 

1. D Placement within the e-JackeUjacket: 

WDefault: (chronological, top = newest) 

D File Location: (PDF page number, i.e., "before page 

45") 

2. D Send to Data Extraction contractors this material: 

D Newly stamped accepted label 

Er Notification 

D NewCSF 

D Other: ____________ _ 

3. Attach this coversheet to the top ofthe material or jacket. It 

must be well organized and clipped together, NOT STAPLED. 

Then give the material with this coversheet to staff in the 

Information Services Center (Room S-4900). 

Reviewer's Name: _-,D~--"'S:...l..c~b-'-\.\)t...;.w.:::::.O-___ _ 

Phone: 3ij~ O~G6 Division: RO I Fe . 

Dale: ____ LA~~~¥~\~\-----------------------

Created August 19, 2008 
UNITED STATES ENVIRONMENTAL PROTEC I,ON AGENCY 

WASHINGTON, DC 20460 

Bayer CropScience 

Laura Phelps 

2 T.W. Alexander Drive 

RTP, NC 27709 

Subject: ETHREL brand Ethephon Plant Growth Regulator 

Registration No.: 264-257 

Date Submitted: 311411 1 

Decision No.: 447178 

PREP brand Ethephon Plant Regulator for Cotton 

Registration No.: 264-380 

Date Submitted: 3114/11 

Decision No.: 447179 

PREP brand Ethephon for Cotton and Tobacco 

Registration No.: 264-418 

Date Submitted: 3114/11 

Decision No.: 447180 

CERONE brand Ethephon Plant Regulator 

Registration No.: 264-377 

Date Submitted: 3114/11 

Decision No.: 447181 

Dear Ms. Phelps: 

OFFICE OF 

CHEMICAL SAFETY AND 

POLLUTION PREVENTION 

MAY 1 1 2011 

The Agency is in receipt of your Applications for Pesticide Notification under Pesticide Registration 

Notice (PRN) 98~ 10. The Registration Division (RD) has conducted a review of this request for its 

applicability under PRN 98~10 and finds that the actions requested fall within the scope ofPRN 98~ 

10. 

The Agency acknowledges the removal of the patent number from the label. 

The label submitted with the application has been stamped "Notification" and will be placed in our 

records. If you have questions concerning this letter, please contact Dominic Schuler at 703~347~0260 or 

via email at schuler.dominic@epa.gov. 

ger22 

Fungicide Branch 

Registration Division (7504P) 

2

UNITED STATES ENVIRONMENTAL PROTEC I,ON AGENCY 

WASHINGTON, DC 20460 

Bayer CropScience 

Laura Phelps 

2 T.W. Alexander Drive 

RTP, NC 27709 

Subject: ETHREL brand Ethephon Plant Growth Regulator 

Registration No.: 264-257 

Date Submitted: 311411 1 

Decision No.: 447178 

PREP brand Ethephon Plant Regulator for Cotton 

Registration No.: 264-380 

Date Submitted: 3114/11 

Decision No.: 447179 

PREP brand Ethephon for Cotton and Tobacco 

Registration No.: 264-418 

Date Submitted: 3114/11 

Decision No.: 447180 

CERONE brand Ethephon Plant Regulator 

Registration No.: 264-377 

Date Submitted: 3114/11 

Decision No.: 447181 

Dear Ms. Phelps: 

OFFICE OF 

CHEMICAL SAFETY AND 

POLLUTION PREVENTION 

MAY 1 1 2011 

The Agency is in receipt of your Applications for Pesticide Notification under Pesticide Registration 

Notice (PRN) 98~ 10. The Registration Division (RD) has conducted a review of this request for its 

applicability under PRN 98~10 and finds that the actions requested fall within the scope ofPRN 98~ 

10. 

The Agency acknowledges the removal of the patent number from the label. 

The label submitted with the application has been stamped "Notification" and will be placed in our 

records. If you have questions concerning this letter, please contact Dominic Schuler at 703~347~0260 or 

via email at schuler.dominic@epa.gov. 

Sincerely, 

~ 

~YKiSh Product M ger 22 

Fungicide Branch 

Registration Division (7504P) 
5 f q l7 of "., Print Form 

JRU"':02~.·~ _______ .... F<>,",~",A~P~'U,~ov~.~d!;-, .;~N!s..·l2207Z02.oo;2!l~'20 .... !::::======l..., 

&EPA United Stotll, 

Environmental Protection Agency 

~ Registration 

Amendment 

aPP Identifier Number 

Wuhington, DC 20460 x Other 

Application for Pesticide M Section I 

1. CompenyJProduct Number 

264-418 

4. Compllny/Produot IName) 

PREP brand Ethephon for Cotton and Tobacco 

5. Namll .~ Addr." of Appticant (Include ZiP (;(Ida, 

Bayer CropScienc€ lP 

P. O. Box 12014; 2 T. W. Alexander Dr. 

Research Trianqle Park, NC 27709 

D Check if thi~ ~,. nllw address 

Amandmont • Expilliin below. 

2. EPA Produot Maneger 

Mr. Tony Kish 

PM' 

22 

3. Propo.ed ClIICljficlltlon 

o None 0 Re.trictod 

6. Expedited Review. In accordance with FIFRA Section 3{cHal 

(b)lj), my product i$ similar at identical in composition and labeling 

to: 

o EPA Reg. No. _______________ _ 

Product Name 

Section - II 

Final printed label. in raaponn to o Agency letter doted ____________ _ 

o 

EI 

Resubmleeion In reeponee to Agancylatter dated ______ _ 

o 

o 

o 

-Me Too" Applicetion. 

Notificetion· Explain below. Other· Explain balow. 

Explanation: U.a additionel pllgel.1 If necenary. IFor aactlon land Section 11.1 

Bayer CropScience is submitting a nolification for PREP brand Ethephon for Cotton and Tobacco to temove the patent numbetfrom the 

label. 

1. Materiel lb. Product WIU a. Pactagad In: 

Child·Reeiatent Pllckoging 

DV"- DNO a CsrtiIication must 

be submitted 

If -VOl- No. par 

Unit Packaging wgt. container 

Section - III 

Water Soluble Packaging 

E3 V .. 

No 

If -VasPackege wgt 

No. per 

contalnar 

3. Location 01 Nltt Contentelnformetion 

o Label 0 Container 

4. Size/sl Ratan Container 

6. Marmar in Which Lebel ia Affixed to Product o Other 

2. Typa of Container 

~::~o Gla .. 

Paper 

Other ISPecifyl _______ 1 

5. Looation ollabal DI,.ctiona 

LI On Labal 

(=:J On Labeling accompanying product 

r-r- Uthograph Paper glued Stencifed 

r-----------------==~~~~~------------~'--~---4 Section .. IV > .... : 

1. Conblct Point {Complete ;tllms dirlilctly billow for identiffcation of individuM To b, contacted. if nece$$ary, to I},hl:f}s:$~th .. oppJic8iion.} , ,-,---~ 

Nllma litle 

Reg. Affairs Specialist , ,1)jeJlJlone N9." Mcltfde Arell Codal 

lauta Phelps 

Certification , , > > , ~ , 

I certify that the ,tatamantIS I have mada on this form and all attachmants thereto ara true, accurate and complata. 

I acknowladg. thol any knowingly fala. or mislDlding atatamont mey b. puni,hebl. by fina or imprilliorvnent or 

both under "Pplicabla laW, 

3. TId_ 

Regulatory Affairs Specialist 

4. Typed Name 

laura Phelps 

EPA Form 8510·1 IRav. 8-941 Pralllous editionl era obaolete, 

5. Date 

March 14,2011 

Whhe • EPA flM Copy Ioriginall 

6. d'a"te APpliCation 

Rac$lved , ; , '(Stamped. 

Vallow • Applicant Copy 

3

5 f q l7 of '-' Ptint Form 

• b.,o,.. .r;,pw jRU",,,,,~"·~ _______ -,F<>,,,,~,,,A.P.'.'~OV~'~d,:;-' .;~N!s..'l2207Z02.oo;2!l~'20"T"::=======-'" 

&EPA United Stot" 

Environmental Protection Agency 

Wuhington, DC 20460 

~ Registration opp Identifier Number 

Amendment 

x Other 

Application for Pesticide M Section I 

1. Compeny/Product Number 

264-418 

4. Company/Produot INama) 

PREP brand Ethephon for Cotton and Tobacco 

5. Name a~ Addran of Appticant (lnc/ud. ZiP (;(Ida} 

Bayer CropScience lP 

P. O. Box 12014; 2 T. W. Alexander Dr. 

Research Trianqle Park, NC 27709 

D Chack if thi~ ~,. nllw address 

Amendment· Expilliin below. 

2. EPA Produot Manllgllr 

Mr. Tony Kish 

PM' 

22 

3. Propo.ed ClIICljficatlon 

o Nona 0 RII.trictod 

6. Expedited Review. In accordance with FIFRA Section 3{cH31 

(b)li), my product i$ similar Ot identical in composition and labellng 

to: 

o EPA Reg. No. _______________ _ 

Product Name 

Section - II 

Final printed label. in rllllpon .. to o Agency letter dotlld 

o 

EI 

Ruubmlellion In r"ponee to AgIIncylettllr dlltod ______ _ 

o 

o 

o 

-Me Too" Applicetion. 

Notificetion - Explain balow. Other - Explain below. 

Explanation: U.II additionel pllgel.1 If mtcenary. IFor IIlIction I lind Section 11.1 

Bayer CropScience is submitting a nolification for PREP brand Ethephon for Cotton and Tobacco to temove the patent numbetfrom the 

label. 

1. Material Th. Product WIU Sa Pactaglld In: 

Child·Rellllltent Packoging 

DV"- DNO 

• CsrtiIication must 

be submitted 

If -VOl- No. pllr 

Unit Packaging wgt, containllr 

Section - III 

Wiltor Soluble Peckaging 

E3 V .. 

No 

If -VasPackllgll wgt 

I 

No. pllr 

contalnllr 

3. Location 01 Nltt Contentelnformetion 

o Lllbel 0 Container 

4. Size/=I Ratan Container 

6. Marmar in Which Lllblll ie Affixed to Product o Othllr 

2. TyplI of Contlllnar 

~::~o GI ... 

Papllr 

Other ISPllcifyl _______ 1 

5. Looetion 01 Lebel Ol,actione 

LI OnLllbal 

(=:J On Labeling accompenying product 

'--f- Uthograph r --- Paper glued ~ __________________________________ ~ .. "S"t,·"e'~;~:·d":C-~ ____ ~~ ________________________ ----7'----;---------~ 

Section M IV > .... : 

1. Conblct Point {Complete itllms dirllct/y billow for identiffcation of individuM To ba contacted, if naclt.sse'Y, to I},hl:f}s:$~th .. oppJicltiion.} -----1 - ;--

Nllmll litllt , ,1)jIlJlJlone N9." Mcltfde Arlla Codel 

lauta Phelps Reg. Affairs Specialist 

Certification , , > > , ~ , 

I certify that the ,totllmentlS I have madll on this form end all attachments tharllto are true, accurate and completa. 

I acknowledgll thol any knowingly flllc, or milileeding statamont mey bll punishllblll by fina or imprilliorvnent or 

both under applicablll laW. 

3. TIde 

Regulatory Affairs Specialist 

4. Typed Namll 

laura Phelps 

EPA Form 8510-1 IRev. 8-941 Prelllou= editionl "re obllolltte. 

5, Date 

March 14,2011 

Whh. - EPA flM Copy Ioriginall 

6. O:te APplication 

Rllc$!ved , ; , '(Stamped. 

V.llow • Applicant Copy 
I 

Bayer Crop Science 

March 10,2011 

Document Processing Desk (NOTIF) 

Registration Division (7505P) 

Office of Pesticide Programs 

U.S. Environmental Protection Agency 

One Potomac Yard (South Building) 

2777 S, Crystal Drive 

Arlington, VA 22202 

Mr. Tony Kish, RD Team 22 

Subject: PREP brand Ethephon for Cotton and Tobacco, No. 264-418; 

Removal of Patent Number 

Dear ML Kish: 

Bayer CropScience is submitting a notification for PREP brand Ethephon for 

Cotton and Tobacco to remove the patent number from the label. 

B 

A 

BAYER 

E 

... R 

Bayer CropScience 

P. 0, Box 12014 

2. T. W. Alexander Drive 

Research Triangle Park, NC 27709 

'" , 

, , , , > " 

This notification is consistent with the provisions ofPR Notice 98-10. No 

other changes have been made to the labeling or the Confidential Statement of 

Formula for this product. I understand that it is a violation of 18 U.S.C. 

Section 1001 to willfully make any false statement to EPA. I further 

understand that if the amended label is not consistent with the requirements of 

40 CFR §§156,10, 156,140, 156.144, 156.146 and 156,156, this product may 

be in violation of FIFRA and I may be subjected to enforcement action and 

penalties under Section 12 and 14 ofFlFRA". , , " " , 

Enclosed are an EPA Form 8570-1 and one copy of the revised PREP brand 

Ethephon for Cotton and Tobacco label for review. 

Please contact me if you should have further questions. 

Sincerely, 

, , " , ) 

, , 

" ) " , , " , , , 

, , , , > , , , 

, 

, , , , , , " , 

, , 

,,"" , , 

, , 

"'" , , 

4

I 

Bayer Crop Science 

March 10,2011 

Document Processing Desk (NOTIF) 

Registration Division (7505P) 

Office of Pesticide Programs 

U.S. Environmental Protection Agency 

One Potomac Yard (South Building) 

2777 S, Crystal Drive 

Arlington, VA 22202 

Mr. Tony Kish, RD Team 22 

Subject: PREP brand Ethephon for Cotton and Tobacco, No. 264-418; 

Removal of Patent Number 

Dear ML Kish: 

Bayer CropScience is submitting a notification for PREP brand Ethephon for 

Cotton and Tobacco to remove the patent number from the label. 

B 

A 

BAYER 

E 

... R 

Bayer CropScience 

P. 0, Box 12014 

2. T. W. Alexander Drive 

Research Triangle Park, NC 27709 

'" , 

, , , , > " 

This notification is consistent with the provisions ofPR Notice 98-10. No 

other changes have been made to the labeling or the Confidential Statement of 

Formula for this product. I understand that it is a violation of 18 U.S.C. 

Section 1001 to willfully make any false statement to EPA. I further 

understand that if the amended label is not consistent with the requirements of 

40 CFR §§156,10, 156,140, 156.144, 156.146 and 156,156, this product may 

be in violation of FIFRA and I may be subjected to enforcement action and 

penalties under Section 12 and 14 ofFlFRA". , , " " , 

Enclosed are an EPA Form 8570-1 and one copy of the revised PREP brand 

Ethephon for Cotton and Tobacco label for review. 

Please contact me if you should have further questions. 

Sincerely, 

, , " , ) 

, , 

" ) " , , " , , , 

, , , , > , , , 

, 

, , , , , , " , 

, , 

,,"" , , 

, , 

"'" , , 
Bayer Crop Science 

Laura Phelps 

Regulatory Affairs, Herbicides & PGRs 

Bayer CropScience 

2 T. W. Alexander Drive 

RTP, NC 27709 

office: 919-549-2302 

mobil:919-352-8075 

email: laura.phelps@bayer.com 

, • , , 0 , 

, , ' , , 

,,,,,, , 

13 

A 

BAYER 

E 

R 

> > > , 

, , J , •• > > , 

> > > , 

, " 

5

Bayer Crop Science 

Laura Phelps 

Regulatory Affairs, Herbicides & PGRs 

Bayer CropScience 

2 T. W. Alexander Drive 

RTP, NC 27709 

office: 919-549-2302 

mobil:919-352-8075 

email: laura.phelps@bayer.com 

, • , , 0 , 

, , ' , , 

,,,,,, , 

13 

A 

BAYER 

E 

R 

> > > , 

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, " 
TM PREP brand Ethephon 

NOTIFICATION 

MAY 1 1 2011 

FOR COTTON AND TOBACCO 

For Commercial Use Or Agricultural Use Only_ Not For Residential Use 

ACTIVE INGREDIENT: Ethephon (2-Chloroethyl) phosphonic acid* ................................................................. 55.4% 

INERT INGREDIENTS: ......................................................................................................................................... 44.60/0 

*This product contains 6 pounds ethephon per galion. 

EPA Reg. No. 264-418 EPA Est. No. 264-PA-Ol 

KEEP OUT OF REACH OF CHILDREN 

DANGER PELIGRO 

Si usled no entiende la etiqueta, busque a alguien para que se la explique a usted en detalle. 

(If you do not understand the label, find someone to explain it to you in detail.) 

For MEDICAL And TRANSPORTATION Emergencies ONLY Call 24 Hours A Day 1-800-334-7577 

For pRODUCI' USE Information Calt 1-866-99BAYER (1-866-992-2937) 

FIRST AID 

IF IN EYES: • Hold eye open and rinse slowly and gently with water for 15-20 minutes. 

• Remove contact lenses, if present, after the lirst 5 minutes, then continue rinsing eye. 

• Call a poison control center or doctor lor treatment advice. 

IF ON SKIN OR • Take off contaminated clothing. 

CLOTHING: 

• Rinse skin immediately with plenty of water for t5-20 minutes. 

• Call a poison control center or doctor for treatment advice. 

IF SWALLOWED: • Immediately call a poison control center or doctor for treatment advice. 

• Do not induce vomiting unless told to do so by a poison control center or doctor. 

• Have person sip a glass 01 water if able to swallow. 

• Do not ive anvthing bv mouth to an unconscious person. 

For MEDICAL Emergencies Call 24 Hours A Day 1-800-334-7577. 

Have the product container or tabel with you when calling a poison controt center or doctor or goine; for treatment. 

NOTE TO PHYSICIAN: Treat symptomatically. Consideration should be given to the possibility that overexposure to materials 

other than this product may have occurred. No specific antidote is available. Probable mucosal damage may contrair.:::I;cs~e the use 

of _gastric lavage 

PRECAUTIONARY STATEMENTS 

DANGER 

HAZARDS TO HUMANS AND DOMESTIC ANIMALS 

CORROSIVE. Causes irreversible eye damage and skin bums. Harmlul if swallowed or absorbed through skir.. Do not Qet in eyes, on 

sk'in or on clothing. 

PERSONAL PROTECTIVE EQUIPMENT (PPE) 

Applicators and other handlers must wear coveralls over short-sleeved shirts and short pants, chemical resistant gl{'lv~~ MR.de 01 any 

waterproof material (such as Nitrile, Butyl, Neoprene and/or Barrier Laminate), chemical-resistant footwear plus socks, protective 

eyewear, chemical-resistant headgear for overhead exposure and chemical-resistant apron when cleaning equipmbnt or mixing and 

loading. 

Discard clothing and other absorbent materials that have been drenched or heavily contaminated with this products concentrate. Do 

not reuse them. Follow manufacturer's instructions for cleaning/maintaining PPE. If no such inslruC1ions for washables, use detergent 

and hot water. Keep and wash PPE separately Irom other laundry. 

6

TM PREP brand Ethephon 

NOTIFICATION 

MAY 1 1 2011 

FOR COTTON AND TOBACCO 

For Commercial Use Or Agricultural Use Only_ Not For Residential Use 

ACTIVE INGREDIENT: Ethephon (2-Chloroethyl) phosphonic acid* ................................................................. 55.4% 

INERT INGREDIENTS: ......................................................................................................................................... 44.60/0 

*This product contains 6 pounds ethephon per galion. 

EPA Reg. No. 264-418 EPA Est. No. 264-PA-Ol 

KEEP OUT OF REACH OF CHILDREN 

DANGER PELIGRO 

Si usled no entiende la etiqueta, busque a alguien para que se la explique a usted en detalle. 

(If you do not understand the label, find someone to explain it to you in detail.) 

For MEDICAL And TRANSPORTATION Emergencies ONLY Call 24 Hours A Day 1-800-334-7577 

For pRODUCI' USE Information Calt 1-866-99BAYER (1-866-992-2937) 

FIRST AID 

IF IN EYES: • Hold eye open and rinse slowly and gently with water for 15-20 minutes. 

• Remove contact lenses, if present, after the lirst 5 minutes, then continue rinsing eye. 

• Call a coison control center or doctor lor treatment advice. 

IF ON SKIN OR • Take off contaminated clothing. 

CLOTHING: 

• Rinse skin immediately with plenty of water for t5-20 minutes. 

• Call a poison control center or doctor for treatment advice. 

IF SWALLOWED: • Immediately call a poison control center or doctor for treatment advice. 

• Do not induce vomiting unless told to do so by a poison control center or doctor. 

• Have person sip a glass 01 water if able to swallow. 

• Do not oive anvthina bv mouth to an unconscious oerson. 

For MEDICAL Emergencies Call 24 Hours A Day 1-800-334-7577. 

Have the Drodue! container or tabel with you when calling_ll_poison controt center or doctor or oin for treatment. 

NOTE TO PHYSICIAN: Treat symptomatically. Consideration should be given to the possibility that overexposure to materials 

other than this product may have occurred. No specific antidote is available. Probable mucosal damage may contrair.:::I;cs~e the use 

of aasttic lavaae 

PRECAUTIONARY STATEMENTS 

DANGER 

HAZARDS TO HUMANS AND DOMESTIC ANIMALS 

CORROSIVE. Causes irreversible eye damage and skin bums. Harmlul if swallowed or absorbed through skir.. Do not Qet in eyes, on 

sk'in or on clothing. 

PERSONAL PROTECTIVE EQUIPMENT (PPE) 

Applicators and other handlers must wear coveralls over short-sleeved shirts and short pants, chemical resistant gl{'lv~~ MRde 01 any 

waterproof material (such as Nitrile, Butyl, Neoprene and/or Barrier Laminate), chemical-resistant footwear plus socks, protective 

eyewear, chemical-resistant headgear for overhead exposure and chemical-resistant apron when cleaning equipmbnt or mixing and 

loading. 

Discard clothing and other absorbent materials that have been drenched or heavily contaminated with this products concentrate. Do 

not reuse them. Follow manufacturer's instructions for cleaning/maintaining PPE. If no such inslruC1ions for washables, use detergent 

and hot water. Keep and wash PPE separately Irom other laundry. 
When handlers use closed systems, enclosed cabs, or aircraft in a manner that meets the requirements listed in the Worker Protection 

Standard (WPS) for agricultural pesticides [40 CFR t70.240 (d) [4-6)], the handler PPE requirements may be reduced or modified as 

specified in the WPS. 

User Safety Recommendations 

Users should wash hands before eating, drinking, chewing gum, using tobacco or using the toilet. 

Users should remove clothing immediately if pesticide gets inside. Then wash body thoroughly and put on clean clothing. 

Users should remove PPE immediately after handling this product. As soon as possible, wash thoroughly and change into clean 

clothing. Wash the outside of gloves before removing. 

ENVIRONMENTAL HAZARDS 

Do not apply directly to water, or to areas where surface water is present or to intertidal areas below the mean high water mark. 

Do not contaminate water when disposing of equipment waShwaters. 

Do not contaminate water used for irrigation or domestic purposes. 

SPRAY DRIFT 

Avoid spray drift. Do not apply when weather conditions may cause drift. Do not allow this product to drift on to non-target areas. Drift 

may result in illegal residues or injury to adjacent crops and vegetation, in the form of leaf yellowing and defoliation. To avoid spray 

drift, DO NOT apply aeria!ly when wind speed is greater than 10 mph or during periods of temperature inversions. Use of larger droplet 

size will also reduce spray drift. 

AVOIDING SPRAY DRIFT AT THE APPLICATION SITE IS THE RESPONSIBILITY OF THE APPLICATOR. 

The interaction of many equipment-and-weather-related factors determine the potential for spray drift. The applicator is responsible for 

considering all these factors when making decisions. 

The following drift management requirements must be followed to avoid off-target movement from aerial applications to agricultural field 

crops. These requirements do not apply to forestry applications, public health uses or to applications using dry formulations. 

1. The distance of the outer most nozzles on the boom must not exceed 3!4the length of the wingspan or rotor. 

2. Nozzles must always point backward parallel with the air stream and never be pointed downwards more than 45 degrees. 

Where states have more stringent regulations, they should be observed. 

The applicator should be familiar with and take into account the information covered in the Aerial Drift Reduction Advisory below: 

AERIAL DRIFT REDUCTION ADVISORY 

[This section is advisory in nature and does not supersede the mandatory label requirements]. 

INFORl~ATION ON DROPLET SIZE 

The most effective way to reduce drift potential is to apply large droplets. The best drift management strategy is to apply the largest 

droplets that provide sufficient coverage and control. Applying larger droplets reduces drift potential, but will not prevent drift if 

applic:ations are made improperly, or under unfavorable environmental conditions (See Wind, Temperature and Humidity, and 

Temperature Inversions). 

CONTROLLING DROPLET SIZE 

Volume - Use high flow rate nozzles to apply the highest practical spray volume. Nozzles with higher rated flows produce larger 

droplets. 

Pressure - Do not exceed the nozzle manufacturer's recommended pressures. For many nozzle types lower pressure prt'lrluces larger 

droplets. When higher flow rates are needed, use higher flow rate nozzles instead of increasing pressure. 

Number of nozzles - Use the minimum number of nozzles that provide uniform coverage. 

Nozzle Orientation - Orienting nozzles so that the spray is released parallel to the airstream prodt,ce$ larger dropletS than other 

orientations and is the recommended practice. Significant deflection from horizontal will reduce droplet :;.ize anti increasp. driit potential. 

Nozzle Type - Use a nozzle type that is designed for the intended application. With most nozzle types, na~rOW9r spray angles produce 

larger droplets. Consider using low-drift nozzles. Solid stream nozzles oriented straight back produce the largest dro;Jle's and the 

lowest drift. 

BOOM LENGTH 

For some use patterns, reducing the effective boom length to less than 3/4 of the wingspan or rotor length may fL:rther reduce drift 

without reducing swath width. 

APPLICATION HEIGHT 

Applications should not be made at a height greater than 10 feet above the top of the target plants unless a greater height is required 

for aircraft safety. Making applications at the lowest height that is safe reduces exposure of droplets to evaporation and wind. 

2 

7

When handlers use closed systems, enclosed cabs, or aircraft in a manner that meets the requirements listed in the Worker Protection 

Standard (WPS) for agricultural pesticides [40 CFR t70.240 (d) [4-6)], the handler PPE requirements may be reduced or modified as 

specified in the WPS. 

User Safety Recommendations 

Users should wash hands before eating, drinking, chewing gum, using tobacco or using the toilet. 

Users should remove clothing immediately if pesticide gets inside. Then wash body thoroughly and put on clean clothing. 

Users should remove PPE immediately after handling this product. As soon as possible, wash thoroughly and change into clean 

clothing. Wash the outside of gloves before removing. 

ENVIRONMENTAL HAZARDS 

Do not apply directly to water, or to areas where surface water is present or to intertidal areas below the mean high water mark. 

Do not contaminate water when disposing of equipment waShwaters. 

Do not contaminate water used for irrigation or domestic purposes. 

SPRAY DRIFT 

Avoid spray drift. Do not apply when weather conditions may cause drift. Do not allow this product to drift on to non-target areas. Drift 

may result in illegal residues or injury to adjacent crops and vegetation, in the form of leaf yellowing and defoliation. To avoid spray 

drift, DO NOT apply aeria!ly when wind speed is greater than 10 mph or during periods of temperature inversions. Use of larger droplet 

size will also reduce spray drift. 

AVOIDING SPRAY DRIFT AT THE APPLICATION SITE IS THE RESPONSIBILITY OF THE APPLICATOR. 

The interaction of many equipment-and-weather-related factors determine the potential for spray drift. The applicator is responsible for 

considering all these factors when making decisions. 

The following drift management requirements must be followed to avoid off-target movement from aerial applications to agricultural field 

crops. These requirements do not apply to forestry applications, public health uses or to applications using dry formulations. 

1. The distance of the outer most nozzles on the boom must not exceed 3!4the length of the wingspan or rotor. 

2. Nozzles must always point backward parallel with the air stream and never be pointed downwards more than 45 degrees. 

Where states have more stringent regulations, they should be observed. 

The applicator should be familiar with and take into account the information covered in the Aerial Drift Reduction Advisory below: 

AERIAL DRIFT REDUCTION ADVISORY 

[This section is advisory in nature and does not supersede the mandatory label requirements]. 

INFORl~ATION ON DROPLET SIZE 

The most effective way to reduce drift potential is to apply large droplets. The best drift management strategy is to apply the largest 

droplets that provide sufficient coverage and control. Applying larger droplets reduces drift potential, but will not prevent drift if 

applic:ations are made improperly, or under unfavorable environmental conditions (See Wind, Temperature and Humidity, and 

Temperature Inversions). 

CONTROLLING DROPLET SIZE 

Volume - Use high flow rate nozzles to apply the highest practical spray volume. Nozzles with higher rated flows produce larger 

droplets. 

Pressure - Do not exceed the nozzle manufacturer's recommended pressures. For many nozzle types lower pressure prt'lrluces larger 

droplets. When higher flow rates are needed, use higher flow rate nozzles instead of increasing pressure. 

Number of nozzles - Use the minimum number of nozzles that provide uniform coverage. 

Nozzle Orientation - Orienting nozzles so that the spray is released parallel to the airstream prodt,ce$ larger dropletS than other 

orientations and is the recommended practice. Significant deflection from horizontal will reduce droplet :;.ize anti increasp. driit potential. 

Nozzle Type - Use a nozzle type that is designed for the intended application. With most nozzle types, na~rOW9r spray angles produce 

larger droplets. Consider using low-drift nozzles. Solid stream nozzles oriented straight back produce the largest dro;Jle's and the 

lowest drift. 

BOOM LENGTH 

For some use patterns, reducing the effective boom length to less than 3/4 of the wingspan or rotor length may fL:rther reduce drift 

without reducing swath width. 

APPLICATION HEIGHT 

Applications should not be made at a height greater than 10 feet above the top of the target plants unless a greater height is required 

for aircraft safety. Making applications at the lowest height that is safe reduces exposure of droplets to evaporation and wind. 

2 
SWATH ADJUSTMENT 

When applications are made with a crosswind, the swath will be displaced downwind. Therefore, on the up and downwind edges of the 

field, the applicator should compensate for this displacement by adjusting the path Of the aircraft upwind. Swath adjustment distance 

should increase, with increasing drift potential (higher wind, smaller drops, etc,). 

WIND 

Drift potential is lowest between wind speeds of 2 - 10 mph. However, many factors, including droplet size and eqUipment type 

determine drift potential at any given speed. Application should be avoided below 2 mph due to variable wind direction and high 

inversion potential. NOTE: Local terrain can influence wind patterns. Every applicator should be familiar with local wind patterns and 

how they affect spray drift. 

TEMPERATURE AND HUMIDITY 

When making applications in low relative humidity, set up equipment to produce larger droplets to compensate for evaporation. Droplet 

evaporation is most severe when conditions are both hot and dry. 

TEMPERATURE INVERSIONS 

Applications should not occur during a temperature inversion because drift potential is high. Temperature inversions restrict vertical air 

mixing, which causes small suspended droplets to remain in a concentrated cloud. This cloud can move in unpredictable directions due 

to the light variable winds common during inversions. Temperature inversions are characterized by increasing temperatures with 

altitude and are common on nights with limited cloud cover and light to no wind. They begin to form as the sun sets and often continue 

into the morning. Their presence can be indicated by ground fog; however, if fog is not present, inversions can also be identified by the 

movement of smoke from a ground source or an aircraft smoke generator. Smoke that layers and moves laterally in a concentrated 

cloud (under low wind conditions) indicates an inversion, while smoke that moves upward and rapidly dissipates indicates good vertical 

air mixing. 

SENSITIVE AREAS 

The pesticide should only be applied when the potential for drift to adjacent sensitive areas (e.g. residential areas, bodies of water, 

known habitat for threatened or endangered species, non-target crops) is minimal (e.g. when wind is blowing away from the sensitive 

areas). 

USE PRECAUTIONS 

Do not apply PREpTM brand Ethephon for Cotton and Tobacco through any type of irrigation system. 

Avoid spray drift to nearby crops as this product will cause modifications in plant growth. Plant injury or reduced yields will result. 

Mix only the amount of spray you expect to use each day. Do not allow mixed solution to stand overnight. 

DIRECTIONS FOR USE 

It is a viotation orFederat taw to use this product in a manner inconsistent with its I:lbeling. 

Do not apply this product in a way that will contact workers or other persons, either directly or through drift. Only protected handlers 

may be in the area during application. For any requirements specific to your State or Tribe, consult the agency responsible for pesticide 

regulations, Read entire label before using this product. 

AGRICULTURAL USE REQUIREMENTS 

Use this product only in accordance with its labeling and with the Worker Protection Standard, 40 CFR part 170. This standard contains 

requirements for the protection of agricultural workers on farms, forests, nurseries, and greenhouses, and handlers of agricultural 

pesticides. It contains requirements for training, decontamination, notification, and emergency assistance. It also contair:s specific 

instructions and exceptions pertaining to the statements on this label about personal protective equipment (PPE), notification to workers 

and restricted-entry intervals. The requirements in this box only apply to uses of this product that are covered by the Worl!'er -='rotection 

Standard. 

Do not enter or anow worker entry into treated areas during the restricted-entry interval (REI) of 48 hourt. The 9.EI is 72 hours in areas 

where average rainfan is less than 25 inches per year. 

PPE required for early entry to treated areas that is permitted under the Worker Protection Standard ar,d that involve~ contact with 

anything that has been treated such as plants, soil or water is coveralls over long-sleeved shirt and long pants, c;lem:ca: resistant 

gloves made of any waterproof material, such as nitrile, butyl, neoprene, or barrier laminate, chemical re3ist;:nt footwear plus socks, 

and protective eyewear. For overhead exposure, chemical-resistant headgear is also required. 

Notify workers of the application by warning them orally and posting warning signs at entrances to treated areas. 

3 

8

SWATH ADJUSTMENT 

When applications are made with a crosswind, the swath will be displaced downwind. Therefore, on the up and downwind edges of the 

field, the applicator should compensate for this displacement by adjusting the path Of the aircraft upwind. Swath adjustment distance 

should increase, with increasing drift potential (higher wind, smaller drops, etc,). 

WIND 

Drift potential is lowest between wind speeds of 2 - 10 mph. However, many factors, including droplet size and eqUipment type 

determine drift potential at any given speed. Application should be avoided below 2 mph due to variable wind direction and high 

inversion potential. NOTE: Local terrain can influence wind patterns. Every applicator should be familiar with local wind patterns and 

how they affect spray drift. 

TEMPERATURE AND HUMIDITY 

When making applications in low relative humidity, set up equipment to produce larger droplets to compensate for evaporation. Droplet 

evaporation is most severe when conditions are both hot and dry. 

TEMPERATURE INVERSIONS 

Applications should not occur during a temperature inversion because drift potential is high. Temperature inversions restrict vertical air 

mixing, which causes small suspended droplets to remain in a concentrated cloud. This cloud can move in unpredictable directions due 

to the light variable winds common during inversions. Temperature inversions are characterized by increasing temperatures with 

altitude and are common on nights with limited cloud cover and light to no wind. They begin to form as the sun sets and often continue 

into the morning. Their presence can be indicated by ground fog; however, if fog is not present, inversions can also be identified by the 

movement of smoke from a ground source or an aircraft smoke generator. Smoke that layers and moves laterally in a concentrated 

cloud (under low wind conditions) indicates an inversion, while smoke that moves upward and rapidly dissipates indicates good vertical 

air mixing. 

SENSITIVE AREAS 

The pesticide should only be applied when the potential for drift to adjacent sensitive areas (e.g. residential areas, bodies of water, 

known habitat for threatened or endangered species, non-target crops) is minimal (e.g. when wind is blowing away from the sensitive 

areas). 

USE PRECAUTIONS 

Do not apply PREpTM brand Ethephon for Cotton and Tobacco through any type of irrigation system. 

Avoid spray drift to nearby crops as this product will cause modifications in plant growth. Plant injury or reduced yields will result. 

Mix only the amount of spray you expect to use each day. Do not allow mixed solution to stand overnight. 

DIRECTIONS FOR USE 

It is a viotation orFederat taw to use this product in a manner inconsistent with its I:lbeling. 

Do not apply this product in a way that will contact workers or other persons, either directly or through drift. Only protected handlers 

may be in the area during application. For any requirements specific to your State or Tribe, consult the agency responsible for pesticide 

regulations, Read entire label before using this product. 

AGRICULTURAL USE REQUIREMENTS 

Use this product only in accordance with its labeling and with the Worker Protection Standard, 40 CFR part 170. This standard contains 

requirements for the protection of agricultural workers on farms, forests, nurseries, and greenhouses, and handlers of agricultural 

pesticides. It contains requirements for training, decontamination, notification, and emergency assistance. It also contair:s specific 

instructions and exceptions pertaining to the statements on this label about personal protective equipment (PPE), notification to workers 

and restricted-entry intervals. The requirements in this box only apply to uses of this product that are covered by the Worl!'er -='rotection 

Standard. 

Do not enter or anow worker entry into treated areas during the restricted-entry interval (REI) of 48 hourt. The 9.EI is 72 hours in areas 

where average rainfan is less than 25 inches per year. 

PPE required for early entry to treated areas that is permitted under the Worker Protection Standard ar,d that involve~ contact with 

anything that has been treated such as plants, soil or water is coveralls over long-sleeved shirt and long pants, c;lem:ca: resistant 

gloves made of any waterproof material, such as nitrile, butyl, neoprene, or barrier laminate, chemical re3ist;:nt footwear plus socks, 

and protective eyewear. For overhead exposure, chemical-resistant headgear is also required. 

Notify workers of the application by warning them orally and posting warning signs at entrances to treated areas. 

3 
STORAGE AND DISPOSAL 

Do not contaminate water, food, or feed by storage or disposal. 

PESTICIDE STORAGE 

Store in a cool, dry place and away from food, feed and other pesticides. IF SPILLED: If container is broken or contents have spilled, 

follow all precautions Indicated above and clean up immediately. Belore cleaning up, put on full length trousers, long sleeved shirt, 

protective gloves, and goggles or face shield. Soak up spill with absorbent media such as sand, earth or other suitable material and 

dispose of waste at an approved waste disposal facility. 

PESTICIDE DISPOSAL 

Pesticide wastes are acutely hazardous. Improper disposal of excess pestlclde, spray mixture, or rinsate is a violation of Federal law. If 

these wastes cannot be disposed of by use according to label instructions, contact your State Pesticide or Environmental Control 

Agency or the Hazardous Waste representative at the nearest EPA Regional Offlce for guidance. 

CONTAINER DISPOSAL 

Rigid, Non-refi!!able containers small enough to shake (I.e., with capacities equal to or tess than 5 gallons) 

Non-refillable container. Do not reuse or retlll this container. Triple rinse or pressure rinse container (or equivalent) promptly after 

emptying. Triple rinse as follows: Empty the remaining contents into application equipment or a mix tank and drain tor to seconds aller 

the flow begins to drip. Fill the container 1/4 full with water and recap. Shake for 10 seconds. Pour rinsate into application equipment or 

a mix tank or store rinsate for later use or disposal. Drain for 10 seconds after the flow begins to drip. Repeat this procedure two more 

times. Once container is rinsed, offer for recycling if available or puncture and dispose of in a sanitary landfill. 

Rigid Non-ref!!!able containers that are too farge to shake (i.e., with capacities greater than 5 gatlons or 50 tbs) 

Non-refillabte Containers 

Non-refillable containers - Do not reuse or rellli this container. Refer to Bottom Discharge IBC or Top Discharge IBC, Drums, Kegs 

intormation as follows. 

Bottom Discharge IBC (e.g. - Schuetz Caged IBC or Snyder Square Stackable) 

Pressure rinsing the container before final disposal is the responsibility of the person disposing of the container. To pressure rinse the 

container before final disposal, empty the remaining contents from the IBC into application equipment or mix tank. Raise the bottom of 

the IBC by 1.5 inches on the side which is oppOsite of the bottom discharge valve to promote more complete product removal. 

Completely remove the top lid ot the IBC. Use water pressurized to at least 40 PSI to rinse all interior portions. Continuously pump or 

drain rinsate into application equipment or rinsate collection system while pressure rinsing. Continue pressure rinsing for 2 minutes or 

until rinsate becomes clear. Replace the lid and close bottom valve. 

Top Discharge IBC, Drums, Kegs (e.g.- Snyder 120 Nex1 Gen, Bonar 8120, Drums, Kegs). 

Triple rinSing the container before final disposal is the responsibility of the person disposing of the container. To triple rinse the 

container betore final disposal, empty the remaining contents from this container into application equipment or mix tank. Fill the 

container at least 10 percent tull with water. Agitate vigorously or recirculate water with the pump for 2 minutes. Rinse all interior 

surfaces. Pour or pump rinsate into application equipment or rinsate collection system. Repeat this procedure two more times. Once 

container is rinsed, offer for recycling if available or puncture and dispose of in a sanitary landf~l. 

Refillabfe Containers 

Refillable container- Refer to Bottom Discharge IBC or Top Discharge IBC, Drums, Kegs information as follows. Retill this container 

with pestiCide only. Do not reuse this container for any other purpose. After emptying product from container, either return container to 

Bayer CropScience per instructions from Bayer CropScience Customer Service Center (1-800-527-4781) or rinse and "ilher roc%le or 

dispose of the container as follows: 

Bottom Discharge fBC (e.g. - Schuetz Caged IBC or Snyder Square Stackable) 

Pressure rinsing the container before flnal disposal is the responsibility of the person disposing of the COl"'t<l.i.,~·. Cleaning b~tore refilling 

is the responsibility of the refiller. To pressure rinse the container before Unal disposal, empty the remaini!'l.g con'ents fr0m th~ IBC into 

appncation equipment or mix tank. Raise the bottom of the IBC by 1.5 inches on the side which is oppOSite ot thA botto!!'l. ai::;charge 

valve to promote more complete product removal. Completely remove the top lid of the IBC. Use water pres.;;uri .. ed to atlp.<lst 40 PSI to 

rinse all interior portions. Continuously pump or drain rinsate into application equipment or rinsate collection system wh;le D,es.;;ure 

rinSing. Continue pressure rinsing for 2 minutes or until rinsate becomes clear. Replace the lid and close bo:tom valve. 

Top Discharge IBC, Drums, Kegs (e.g.- Snyder 120 Next Gen, Bonar 8120, Drums, Kegs). 

Triple rinsing the container before final disposal is the responsibility of the person disposing of the container. Cleaning Lefore retming is 

the responsibility ot the refliler. To triple rinse the containers before tinal disposal, empty the remaining contents from th:s cor,tainer into 

application equipment or mix tank. Fill the container at least 10 percent full with water. Agitate vigorously or recirculate \'/ater with the 

pump for 2 minutes. Rinse all interior surfaces. Pour or pump rinsate into application equipment or rinsate collection system. Repeat this 

procedure two more times. Once container is rinsed, offer for recycling it available or puncture and dispose of in a sanitary landfill. 

4 

9

STORAGE AND DISPOSAL 

Do not contaminate water, food, or feed by storage or disposal. 

PESTICIDE STORAGE 

Store in a cool, dry place and away from food, feed and other pesticides. IF SPILLED: If container is broken or contents have spilled, 

follow all precautions Indicated above and clean up immediately. Belore cleaning up, put on full length trousers, long sleeved shirt, 

protective gloves, and goggles or face shield. Soak up spill with absorbent media such as sand, earth or other suitable material and 

dispose of waste at an approved waste disposal facility. 

PESTICIDE DISPOSAL 

Pesticide wastes are acutely hazardous. Improper disposal of excess pestlclde, spray mixture, or rinsate is a violation of Federal law. If 

these wastes cannot be disposed of by use according to label instructions, contact your State Pesticide or Environmental Control 

Agency or the Hazardous Waste representative at the nearest EPA Regional Offlce for guidance. 

CONTAINER DISPOSAL 

Rigid, Non-refi!!able containers small enough to shake (I.e., with capacities equal to or tess than 5 gallons) 

Non-refillable container. Do not reuse or retlll this container. Triple rinse or pressure rinse container (or equivalent) promptly after 

emptying. Triple rinse as follows: Empty the remaining contents into application equipment or a mix tank and drain tor to seconds aller 

the flow begins to drip. Fill the container 1/4 full with water and recap. Shake for 10 seconds. Pour rinsate into application equipment or 

a mix tank or store rinsate for later use or disposal. Drain for 10 seconds after the flow begins to drip. Repeat this procedure two more 

times. Once container is rinsed, offer for recycling if available or puncture and dispose of in a sanitary landfill. 

Rigid Non-ref!!!able containers that are too farge to shake (i.e., with capacities greater than 5 gatlons or 50 tbs) 

Non-refillabte Containers 

Non-refillable containers - Do not reuse or rellli this container. Refer to Bottom Discharge IBC or Top Discharge IBC, Drums, Kegs 

intormation as follows. 

Bottom Discharge IBC (e.g. - Schuetz Caged IBC or Snyder Square Stackable) 

Pressure rinsing the container before final disposal is the responsibility of the person disposing of the container. To pressure rinse the 

container before final disposal, empty the remaining contents from the IBC into application equipment or mix tank. Raise the bottom of 

the IBC by 1.5 inches on the side which is oppOsite of the bottom discharge valve to promote more complete product removal. 

Completely remove the top lid ot the IBC. Use water pressurized to at least 40 PSI to rinse all interior portions. Continuously pump or 

drain rinsate into application equipment or rinsate collection system while pressure rinsing. Continue pressure rinsing for 2 minutes or 

until rinsate becomes clear. Replace the lid and close bottom valve. 

Top Discharge IBC, Drums, Kegs (e.g.- Snyder 120 Nex1 Gen, Bonar 8120, Drums, Kegs). 

Triple rinSing the container before final disposal is the responsibility of the person disposing of the container. To triple rinse the 

container betore final disposal, empty the remaining contents from this container into application equipment or mix tank. Fill the 

container at least 10 percent tull with water. Agitate vigorously or recirculate water with the pump for 2 minutes. Rinse all interior 

surfaces. Pour or pump rinsate into application equipment or rinsate collection system. Repeat this procedure two more times. Once 

container is rinsed, offer for recycling if available or puncture and dispose of in a sanitary landf~l. 

Refillabfe Containers 

Refillable container- Refer to Bottom Discharge IBC or Top Discharge IBC, Drums, Kegs information as follows. Retill this container 

with pestiCide only. Do not reuse this container for any other purpose. After emptying product from container, either return container to 

Bayer CropScience per instructions from Bayer CropScience Customer Service Center (1-800-527-4781) or rinse and "ilher roc%le or 

dispose of the container as follows: 

Bottom Discharge fBC (e.g. - Schuetz Caged IBC or Snyder Square Stackable) 

Pressure rinsing the container before flnal disposal is the responsibility of the person disposing of the COl"'t<l.i.,~·. Cleaning b~tore refilling 

is the responsibility of the refiller. To pressure rinse the container before Unal disposal, empty the remaini!'l.g con'ents fr0m th~ IBC into 

appncation equipment or mix tank. Raise the bottom of the IBC by 1.5 inches on the side which is oppOSite ot thA botto!!'l. ai::;charge 

valve to promote more complete product removal. Completely remove the top lid of the IBC. Use water pres.;;uri .. ed to atlp.<lst 40 PSI to 

rinse all interior portions. Continuously pump or drain rinsate into application equipment or rinsate collection system wh;le D,es.;;ure 

rinSing. Continue pressure rinsing for 2 minutes or until rinsate becomes clear. Replace the lid and close bo:tom valve. 

Top Discharge IBC, Drums, Kegs (e.g.- Snyder 120 Next Gen, Bonar 8120, Drums, Kegs). 

Triple rinsing the container before final disposal is the responsibility of the person disposing of the container. Cleaning Lefore retming is 

the responsibility ot the refliler. To triple rinse the containers before tinal disposal, empty the remaining contents from th:s cor,tainer into 

application equipment or mix tank. Fill the container at least 10 percent full with water. Agitate vigorously or recirculate \'/ater with the 

pump for 2 minutes. Rinse all interior surfaces. Pour or pump rinsate into application equipment or rinsate collection system. Repeat this 

procedure two more times. Once container is rinsed, offer for recycling it available or puncture and dispose of in a sanitary landfill. 

4 
Refillabfe Containers 

End users are authorized to remove tamper evident cables as required to remove the product from the container unless the container is 

equipped with one way valves and refilling or retuming is planned. If this is the case, end users are not authorized to remove tamper 

evident cables, one way valves or clean container. See Container Disposal instructions under Storage and Disposal. 

GENERALINFO~TION 

COlTON 

A foliar spray of PREPwl brand Ethephon for Cotton and Tobacco will accelerate opening of mature unopened cotton bolls and enhance 

defoliation which can result in earlier harvest with an increased recoverable yield. PREpTM brand Ethephon for Cotton and Tobacoo 

treatment on cotton allows increased efficiency from a once-over harvest. 

TOBACCO (FLUE-CURED): A foliar spray of PREpTM brand Ethephon for Cotton and Tobacco promotes early, uniform 'yellowing" of 

mature tobacco. PREpTM brand Ethephon for Cotton and Tobacco reduces curing time, allowing more efficient use of curing barn 

space, and increased control over harvest schedules. 

SPRAY PREPARATION 

Add 1/2 to 3/4 of the required amount of water to the spray tank. Start agitation. Add the required amount of PREpTM brand Ethephon 

for Cotton and Tobacco, and the remaining amount of water. Prepare only as much spray solution as can be used on the day of mixing. 

Do not allow spray solution to stand ovemight Do not spill the concentrated product on spray equipment, or any airplane parts. 

ANY SPILLS SHOULD BE RINSED IMMEDIATELY WITH PLENTY OF WATER. 

Use of a nurse tank is highly recommended for avoiding possible spills of concentrated formulation on spray equipment or any airplane 

parts. 

TANK MIXTURES WITH DEFOLIANTS AND INSECTICIDES 

PREpTM brand Ethephon for Cotton and Tobacco is compatible with DEf=®, FOLEX®, Dropp®. Dropp® UJtraTM, Ginstar®, Harvade®, 

Methyl Parathion, Guthion®, and MalathionTM. PREpTM brand Ethephon for Cotton and Tobacco may be applied in sequence or as a 

tank mixture (DO NOT TANK MIX WITH DESICCANTS IF COTTON IS TO BE SPINDLE HARVESTED). Follow all applicable use 

precautions and rate per acre recommendations on labels of products applied as tank mixtures or in sequence with PREP TM brand 

Ethephon for Cotton and Tobacco. In some cases slight reduction in boll opening response has been observed when tank mixes with 

defoliants were used. 

Good agitation in the spray tank is essential and a tank mixture should not be allowed to stand without agitation for more than 5 to 10 

minutes. Read and observe all appropriate label use directions and precautions for the defoliants and insecticides used. 

NOTE: UNDER CERTAIN CONDITIONS, TANK MIXTURES OF PREpTM BRAND ETHEPHON FOR COTTON AND TOBACCO WITH 

DESICCANTS CONTAINING SODIUM CHLORATE COULD RESULT IN THE FORMATION OF HYPOCHLOROUS ACIDS WHICH 

ON HEATING WILL EMIT TOXIC CHLORIDE FUMES. 

DO NOT MIX PREpTM BRAND ETHEPHON FOR COTTON AND TOBACCO WITH AMMONIUM THIOSULFATE. SUCH TANK 

MIXTURES MAY RESULT IN FORMATION OF TOXIC FUMES. 

EQUIPMENT CLEANING 

Because of the acidic nature of this product, prolonged exposure to spray deposit will damage acrylic plastics, certain paints, and 

metals. 

Rinse thoroughly with a detergent and water all exposed acrylic plastic-type materials (e.g., aircraft windshields), and painted surfaces 

within an hour after exposure to spray depOSits. 

At the end of each day, rinse thoroughly with a detergent and water all the metal parts of the aircratt and the associated spray 

equipment exposed to the spray deposits. 

5 

10

Refillabfe Containers 

End users are authorized to remove tamper evident cables as required to remove the product from the container unless the container is 

equipped with one way valves and refilling or retuming is planned. If this is the case, end users are not authorized to remove tamper 

evident cables, one way valves or clean container. See Container Disposal instructions under Storage and Disposal. 

GENERALINFO~TION 

COlTON 

A foliar spray of PREPwl brand Ethephon for Cotton and Tobacco will accelerate opening of mature unopened cotton bolls and enhance 

defoliation which can result in earlier harvest with an increased recoverable yield. PREpTM brand Ethephon for Cotton and Tobacoo 

treatment on cotton allows increased efficiency from a once-over harvest. 

TOBACCO (FLUE-CURED): A foliar spray of PREpTM brand Ethephon for Cotton and Tobacco promotes early, uniform 'yellowing" of 

mature tobacco. PREpTM brand Ethephon for Cotton and Tobacco reduces curing time, allowing more efficient use of curing barn 

space, and increased control over harvest schedules. 

SPRAY PREPARATION 

Add 1/2 to 3/4 of the required amount of water to the spray tank. Start agitation. Add the required amount of PREpTM brand Ethephon 

for Cotton and Tobacco, and the remaining amount of water. Prepare only as much spray solution as can be used on the day of mixing. 

Do not allow spray solution to stand ovemight Do not spill the concentrated product on spray equipment, or any airplane parts. 

ANY SPILLS SHOULD BE RINSED IMMEDIATELY WITH PLENTY OF WATER. 

Use of a nurse tank is highly recommended for avoiding possible spills of concentrated formulation on spray equipment or any airplane 

parts. 

TANK MIXTURES WITH DEFOLIANTS AND INSECTICIDES 

PREpTM brand Ethephon for Cotton and Tobacco is compatible with DEf=®, FOLEX®, Dropp®. Dropp® UJtraTM, Ginstar®, Harvade®, 

Methyl Parathion, Guthion®, and MalathionTM. PREpTM brand Ethephon for Cotton and Tobacco may be applied in sequence or as a 

tank mixture (DO NOT TANK MIX WITH DESICCANTS IF COTTON IS TO BE SPINDLE HARVESTED). Follow all applicable use 

precautions and rate per acre recommendations on labels of products applied as tank mixtures or in sequence with PREP TM brand 

Ethephon for Cotton and Tobacco. In some cases slight reduction in boll opening response has been observed when tank mixes with 

defoliants were used. 

Good agitation in the spray tank is essential and a tank mixture should not be allowed to stand without agitation for more than 5 to 10 

minutes. Read and observe all appropriate label use directions and precautions for the defoliants and insecticides used. 

NOTE: UNDER CERTAIN CONDITIONS, TANK MIXTURES OF PREpTM BRAND ETHEPHON FOR COTTON AND TOBACCO WITH 

DESICCANTS CONTAINING SODIUM CHLORATE COULD RESULT IN THE FORMATION OF HYPOCHLOROUS ACIDS WHICH 

ON HEATING WILL EMIT TOXIC CHLORIDE FUMES. 

DO NOT MIX PREpTM BRAND ETHEPHON FOR COTTON AND TOBACCO WITH AMMONIUM THIOSULFATE. SUCH TANK 

MIXTURES MAY RESULT IN FORMATION OF TOXIC FUMES. 

EQUIPMENT CLEANING 

Because of the acidic nature of this product, prolonged exposure to spray deposit will damage acrylic plastics, certain paints, and 

metals. 

Rinse thoroughly with a detergent and water all exposed acrylic plastic-type materials (e.g., aircraft windshields), and painted surfaces 

within an hour after exposure to spray depOSits. 

At the end of each day, rinse thoroughly with a detergent and water all the metal parts of the aircratt and the associated spray 

equipment exposed to the spray deposits. 

5 
COTTON 

USE EXPECTED PREprM BRAND ONE MINL"IUM SPRAY APPLICATION 

CONDITIONS ETHEPHON FOR GALLON VOLUMES TIMING 

COITONAND PREprn (G:tts/A)* 

TOBACCO BRAND 

RATE ETHEPHO 

NFOR 

COTTON 

AND 

TOBACCO 

TREATS 

P,ntslA LBS A.I. Acres Ground Air*"'** 

PREpr~· brand Hoi and dry aO"F or 1 1/3 1.0 6 Apply when the number of 

ETHEPHo."l" FOR higher mature unopened bolls ;s 

COTIONAND Dry and 75 to 80"F 2 1.5 4 sufficient to produce th, 

TOBACCO 10 2 desired crop. See below for 

Boll Opener"" Cool but above 65"F 2213 2.0 3 test ot boll maturity. 

Treatment uniformly opens 

0' bolls 7 to 14 days earller. 

Rank cotton 

PREPTM brand High soil moisture 113 0.25 24 10 5 Apply 4 to 7 days prior to 

ETHEPHON FOR 0' PREpTM brand Ethephon for 

CQITONAND High fertiJfly level Cotton aod Tobacco boll 

TOBACCO + opening application. To be 

FOLE.X® 0' used as a sequential 

Defoliant Tank Rank cotton treatment with, not in place 

M'x*** 

of PREpTM brand Ethephon 

for Cotton and Tobacco boll 

ooening treatment. 

PREpriU brand High soil moisture tl3 0.25 24 10 3 Apply 4 to 7 days prior to 

ETHEPHON FOR 0' PREpTM brand Ethephon for 

COTTON AND High fertility level Cotton aod Tobacco boll 

TOBACCO + Dropp opening application. To be 

0' used as a sequential Defoliant Tank 

Mix*** Rank cotton treatment with, not in place 

of PREpTM brand Ethephon 

for Cotton and Tobacco boll 

ooenino treatment. 

Pre~CoDd<t'oner r" Hot, dry, above 213 0.5 12 Apply 4 to 7 days prior to 

DefbHation aO"F 1113 1.0 6 to 2 defoliant. Enhances top 

Cool, above 65"F crop defoliation reduCing 

deterioration of bottom crop 0' aod allows :0r earlier 

Rank cotton harvest. 

* For best performance, by ground or air application, choose equipment and spray volumes that will insure uniform cC'ver?,ge of foliage 

and bolls. 

"* Pretrentment With Defoliants Prior to PREPTM brand Ethephon for Cotton and Tobacco Bo:1 Oflel,ing Treatment: If the 

cotton is over1y rank or laying down in the middles and good spray coverage of the bolls with PREpTM brand EIt,dr-\;1011 jar Cotton 

and Tobacco is difficult, a pretreatmem with defoliants will be useful to improve boll coverage with PRErTM brand Ethephon for 

Cotton and Tobacco. Use dosage rates of PREpTM brand Ethephon for Cotton and Tobacco recommended for bdl op:m::1g. Read 

and observe all appropriate label use directions and precautions for the defoliant used. 

*"* Can use up to full label rate for each product. 

**** In California and Arizona use a volume of no less than 5 gallons per acre for aerial applications. 

Boll Maturity 

A boll is mature when it is too hard to be dented when squeezed between thumb and fingers, too hard to be sliced with a sharp knife, 

and when the seed coat becomes light brown in color. 

Use Limitntions 

Do not exceed a maximum of 2.0 lb. ethephon active ingredient per acre per year through combined or repeated uses of any 

ethephon products. 

6 

11

COTTON 

USE EXPECTED PREprM BRAND ONE MINL"IUM SPRAY APPLICATION 

CONDITIONS ETHEPHON FOR GALLON VOLUMES TIMING 

COITONAND PREprn (G:tts/A)* 

TOBACCO BRAND 

RATE ETHEPHO 

NFOR 

COTTON 

AND 

TOBACCO 

TREATS 

P,ntslA LBS A.I. Acres Ground Air*"'** 

PREpr~· brand Hoi and dry aO"F or 1 1/3 1.0 6 Apply when the number of 

ETHEPHo."l" FOR higher mature unopened bolls ;s 

COTIONAND Dry and 75 to 80"F 2 1.5 4 sufficient to produce th, 

TOBACCO 10 2 desired crop. See below for 

Boll Opener"" Cool but above 65"F 2213 2.0 3 test ot boll maturity. 

Treatment uniformly opens 

0' bolls 7 to 14 days earller. 

Rank cotton 

PREPTM brand High soil moisture 113 0.25 24 10 5 Apply 4 to 7 days prior to 

ETHEPHON FOR 0' PREpTM brand Ethephon for 

CQITONAND High fertiJfly level Cotton aod Tobacco boll 

TOBACCO + opening application. To be 

FOLE.X® 0' used as a sequential 

Defoliant Tank Rank cotton treatment with, not in place 

M'x*** 

of PREpTM brand Ethephon 

for Cotton and Tobacco boll 

openina treatment. 

PREpriU brand High soil moisture tl3 0.25 24 10 3 Apply 4 to 7 days prior to 

ETHEPHON FOR 0' PREpTM brand Ethephon for 

COTTON AND High fertility level Cotton aod Tobacco boll 

TOBACCO + Dropp opening application. To be 

0' used as a sequential DeColiant Tank 

Mix*** Rank cotton treatment with, not in place 

of PREpTM brand Ethephon 

for Cotton and Tobacco boll 

openino treatment. 

Pre~CoDd<t'oner r" Hot, dry, above 213 0.5 12 Apply 4 to 7 days prior to 

DefbHation aO"F 1113 1.0 6 to 2 defoliant. Enhances top 

Cool, above 65"F crop defoliation reduCing 

deterioration of bottom crop 0' aod allows :0r earlier 

Rank cotton harvest. 

* For best performance, by ground or air application, choose equipment and spray volumes that Will Insure uniform cC'ver?,ge of foliage 

and bolls. 

"* Pretrentment With Defoliants Prior to PREPTM brand Ethephon Cor Cotton and Tobacco Bo:1 Oflel,ing Treatment: If the 

cotton is overly rank or laying down in the middles and good spray coverage of the bolls with PREpTM brand EIt,dr-\;1011 jar Cotton 

and Tobacco is difficult, a pretreatmem with defoliants will be useful to improve boll coverage with PRErTM brand Ethephon for 

Cotton and Tobacco. Use dosage rates of PREpTM brand Ethephon for Cotton and Tobacco recommended for bdl op:m::1g. Read 

and observe all appropriate label use directions and precautions for the defoliant used. 

*"* Can use up to full label rate for each product. 

**** In California and Arizona use a volume of no less than 5 gallons per acre for aerial applications. 

Boll Maturity 

A boll is mature when it is too hard to be dented when squeezed between thumb and fingers, too hard to be sliced with a sharp knife, 

and when the seed coat becomes light brown in color. 

Use Limitntions 

Do not exceed a maximum of 2.0 lb. ethephon active ingredient per acre per year through combined or repeated uses of any 

ethephon products. 

6 
Boll Opening: 00 not tank mix PREpTM brand Ethephon tor Cotton and Tobacco with a desiccant if the cotton is to be spindle 

harvested. 

Pre-Condition for Defoliation: Do not tank nix PREpTM brand Ethephon for Cotton and Tobacco with desiccants unless plant 

desiccation is required. 00 not use a defoliant before there is sufficient mature unopened bolls to produce the desired yield (see 

General Intormation section on how to test for boll maturity. 

00 NOT APPLY PREpTM BRAND ETHEPHON FOR COTTON AND TOBACCO IF RAIN IS EXPECTED WITHIN 6 HOURS. 

Rainfall within 6 hours of application may reduce product performance. 

00 not plant another crop within 30 days after treatment. Small grains planted earlier than 1 month or intercropped with the cotton 

crop to which PREpTM brand Ethephon for Cotton and Tobacco will be applied may only be used as cover crops and may not be 

harvested for toad or feed. PREpTM brand Ethephon for Callan and Tobacco may cause yellowing and growth inhibition of treated 

small grains. 

WHEN TO HARVEST COTTON 

00 not harvest cotton sooner than 7 days after a treatment with PREpTM brand Ethephon for Cotton and Tobacco. 

Observe the treated crop and harvest when optimum boll opening has been reached. Too early harvest might reduce the full advantage 

of the treatment and too late a harvest may result in reduced quality and loss of lint which will drop tram the plant. 

PREpnl brand 

Crop Situation Ethephon for 

Cotton aod 

Tobacco 

Pints/Acre 

Directed Spray 1 1/3 

Application 

Over-The-Top t 113-2213 

Application 

USE LIMITATIONS 

TOBACCO 

(Flue-Cured Only) 

Mioimum Spray 

Votumes 

Gallons/ Specific Directions 

Acre 

50 Use drop nozzles. Choose TG or DC spray tips designed to apply 50 - 60 

gpa at 35-40 psi and at tractor speed of 2-3 mph. Use 

2 nozzles per row; one on each side of the row dropped low enough to direct 

the spray to the leaves to be ripened and harvested. Thorough spray 

coverage is essential. With a directed spray, be sure to harvest all leaves 

with 20% or more yellowing. 

40 Treat only when leaves remaining on the stalk are mature. To ensure 

remaining leaves are mature, test spray several tobacco plants as described 

under the section "Proper Time of Treatment." Use the lower rate in a 

normally mature crop when experience indicates that minimum ripening 

inducement is required. Use the higher rate when the crop is heavy and has 

a tendency to be more rank or when temperatures are lower than normal. 

Always test spray to determine if the tobacco is mature enough to respond 

to treatment w'rth PREpTM brand Ethephon for Cotton and Tobacco. 

Apply over-the-top PREpTM brand Ethephon for Cotton and Tobacco spray 

as a fine mist using three nozzles (one nozzle tip over the center of the 

plant, and one on each side) so all leaves are covered thoroughly, similar to 

the application pattern of systemic sucker control agents. l'e~ a spray 

I pressure ot 40 to 60 psi, 

00 not apply PREpTM brand Ethephon for Cotton and Tobacco to immature leaves as this can result in unsatisfactory coloring, 

weight loss and reduced leaf quality. 

00 not allow the crop to over ripen in the field after using PREpTM brand Ethephon for Cotton and Tobacco, s!nc~ tllh, may cause 

some reduction in yield and quality. 

00 not treat before anticipated major storm which could prevent harvest and result in crop loss. 

00 NOT APPLY PREpTM BRAND ETHEPHON FOR COTTON AND TOBACCO IF RAIN IS E~~r[C7ED WITHIN 6 HOURS. 

Rainfall within 6 hours of application may reduce product performance. 

00 not use PREpTM brand Ethephon tor Cotton and Tobacco with additives other than recommended on this label. 

00 not plant another crop within 30 days after treatment. 

00 not exceed a maximum of 2 Ibs ethephon active ingredient per acre per year through repeated uses of any ethephon products. 

7 

12

Boll Opening: 00 not tank mix PREpTM brand Ethephon tor Cotton and Tobacco with a desiccant if the cotton is to be spindle 

harvested. 

Pre-Condition for Defoliation: Do not tank nix PREpTM brand Ethephon for Cotton and Tobacco with desiccants unless plant 

desiccation is required. 00 not use a defoliant before there is sufficient mature unopened bolls to produce the desired yield (see 

General Intormation section on how to test for boll maturity. 

00 NOT APPLY PREpTM BRAND ETHEPHON FOR COTTON AND TOBACCO IF RAIN IS EXPECTED WITHIN 6 HOURS. 

Rainfall within 6 hours of application may reduce product performance. 

00 not plant another crop within 30 days after treatment. Small grains planted earlier than 1 month or intercropped with the cotton 

crop to which PREpTM brand Ethephon for Cotton and Tobacco will be applied may only be used as cover crops and may not be 

harvested for toad or feed. PREpTM brand Ethephon for Callan and Tobacco may cause yellowing and growth inhibition of treated 

small grains. 

WHEN TO HARVEST COTTON 

00 not harvest cotton sooner than 7 days after a treatment with PREpTM brand Ethephon for Cotton and Tobacco. 

Observe the treated crop and harvest when optimum boll opening has been reached. Too early harvest might reduce the full advantage 

of the treatment and too late a harvest may result in reduced quality and loss of lint which will drop tram the plant. 

PREpnl brand 

Crop Situation Ethephon for 

Cotton aod 

Tobacco 

Pints/Acre 

Directed Spray 1 1/3 

Application 

Over-The-Top t 113-2213 

Application 

USE LIMITATIONS 

TOBACCO 

(Flue-Cured Only) 

Mioimum Spray 

Votumes 

Gallons/ Specific Directions 

Acre 

50 Use drop nozzles. Choose TG or DC spray tips designed to apply 50 - 60 

gpa at 35-40 psi and at tractor speed of 2-3 mph. Use 

2 nozzles per row; one on each side of the row dropped low enough to direct 

the spray to the leaves to be ripened and harvested. Thorough spray 

coverage is essential. With a directed spray, be sure to harvest all leaves 

with 20% or more vellowino. 

40 Treat only when leaves remaining on the stalk are mature. To ensure 

remaining leaves are mature, test spray several tobacco plants as described 

under the section "Proper Time of Treatment." Use the lower rate in a 

normally mature crop when experience indicates that minimum ripening 

inducement is required. Use the higher rate when the crop is heavy and has 

a tendency to be more rank or when temperatures are lower than normal. 

Always test spray to determine if the tobacco is mature enough to respond 

to treatment w'rth PREpTM brand Ethephon for Cotton and Tobacco. 

Apply over-the-top PREpTM brand Ethephon for Cotton and Tobacco spray 

as a fine mist using three nozzles (one nozzle tip over the center of the 

plant, and one on each side) so all leaves are covered thoroughly, similar to 

the application pattern of systemic sucker control agents. I pressure ot 40 to 6Qpsi, 

l'e~ a spray 

00 not apply PREpTM brand Ethephon for Cotton and Tobacco to immature leaves as this can result in unsatisfactory coloring, 

weight loss and reduced leaf quality. 

00 not allow the crop to over ripen in the field after using PREpTM brand Ethephon for Cotton and Tobacco, s!nc~ tin" may cause 

some reduction in yield and quality. 

00 not treat before anticipated major storm which could prevent harvest and result in crop loss. 

00 NOT APPLY PREpTM BRAND ETHEPHON FOR COTTON AND TOBACCO IF RAIN IS E~~r[C7ED WITHIN 6 HOURS. 

Rainfall within 6 hours of application may reduce product performance. 

00 not use PREpTM brand Ethephon tor Cotton and Tobacco with additives other than recommended on this label. 

00 not plant another crop within 30 days after treatment. 

00 not exceed a maximum of 2 Ibs ethephon active ingredient per acre per year through repeated uses of any ethephon products. 

7 
APPLICATION TIMING 

Successful results with PREpTM brand Ethephon for Cotton and Tobacco call for treatment When leaves are mature, not overly rank 

green when sprayed. To easily determine the proper treatment timing and the number of leaves per stalk ready for harvest, test spray 

several plants in more than one location in each field and observe the response. Mature leaves will begin to yellow in 24 to 72 hours. 

Test leaves that fail to yellow in 72 hours are not mature and are not ready for PREpTM brand Ethephon for Cotton and Tobacco 

treatment. Wait a few days to permit further natural maturing, then make another test spray or 'maturity" check. 

To avoid quality loss and or possible leaf drop, harvest any yeJlowed leaves prior to application. Use lower rates under most conditions. 

Limit use of higher rates to cool (below 65Q

F at the time of treatment) slow ripening conditions. 

When you have confirmed the desired number of leaves per plant that will color, you can determine the number of acres to treat in order 

to till the barn. 

Prepare your test spray by mixing one teaspoon of PREpTM brand Ethephon for Cotton and Tobacco in 1 quart of water. Spray each 

test plant with about 1 oz. of this mixture, covering all leaves with a fine mist. PREpTM brand Ethephon for Cotton and Tobacco will not 

color immature sprayed leaves. 

WHEN TO HARVEST 

All mature, sprayed leaves will begin to color within 24 to 72 hours after PREpTM brand Ethephon for Cotton and Tobacco application. 

The yellOW'lng process is weather dependent; cool weather will delay, while hot, sunny weather can speed up the process. Harvest 

treated tobacco when leaves have reached the desired color intensity. 

Harvest can commence 48 hours after PREpTM brand Ethephon for Cotton and T obaceo application. To determine harvest timing and 

avoid quality loss or leaf drop, closely monitor treated crop and weather conditions. 

CURING PREpm BRAND ETHEPHONFOR COTTON AND TOBACCO TREATED TOBACCO 

Curing procedures are as much an art as a science and each cure must be iudged on the basis of tobacco condition, interval between 

treatment and harvest, weather and type of curing facility before.prescription temperature and Ventilation schedules can be established. 

To obtain maximum quality, care must be taken to observe and control the curing process closely, especiaUy during the late "coloring" 

and early "drying' stages of the leaf. 

PAEpTM brand Ethephon for Cotton and Tobacco treated tobacco will have started the coloring process when harvested, reducing the 

time required in the coloring phase of curing. Treated tobacco should be dried faster. If tobacco leaves are green or contain some 

green when harvested, it may be necessary to color them for a few hours. If the leaves are completely yelloW, temperature and 

ventilation must be adjusted in a manner to dry the tobacco as fast as possible without scalding. Once the leaf is dried (314 dry), you 

should follow normal procedures tor curing. Since PREpM brand Ethephon for Cotton and Tobacco treated leaves cure faster, treated 

and untreated leaves should not be cured together in the same barn. 

8 

13

APPLICATION TIMING 

Successful results with PREpTM brand Ethephon for Cotton and Tobacco call for treatment When leaves are mature, not overly rank 

green when sprayed. To easily determine the proper treatment timing and the number of leaves per stalk ready for harvest, test spray 

several plants in more than one location in each field and observe the response. Mature leaves will begin to yellow in 24 to 72 hours. 

Test leaves that fail to yellow in 72 hours are not mature and are not ready for PREpTM brand Ethephon for Cotton and Tobacco 

treatment. Wait a few days to permit further natural maturing, then make another test spray or 'maturity" check. 

To avoid quality loss and or possible leaf drop, harvest any yeJlowed leaves prior to application. Use lower rates under most conditions. 

Limit use of higher rates to cool (below 65Q

F at the time of treatment) slow ripening conditions. 

When you have confirmed the desired number of leaves per plant that will color, you can determine the number of acres to treat in order 

to till the barn. 

Prepare your test spray by mixing one teaspoon of PREpTM brand Ethephon for Cotton and Tobacco in 1 quart of water. Spray each 

test plant with about 1 oz. of this mixture, covering all leaves with a fine mist. PREpTM brand Ethephon for Cotton and Tobacco will not 

color immature sprayed leaves. 

WHEN TO HARVEST 

All mature, sprayed leaves will begin to color within 24 to 72 hours after PREpTM brand Ethephon for Cotton and Tobacco application. 

The yellOW'lng process is weather dependent; cool weather will delay, while hot, sunny weather can speed up the process. Harvest 

treated tobacco when leaves have reached the desired color intensity. 

Harvest can commence 48 hours after PREpTM brand Ethephon for Cotton and T obaceo application. To determine harvest timing and 

avoid quality loss or leaf drop, closely monitor treated crop and weather conditions. 

CURING PREpm BRAND ETHEPHONFOR COTTON AND TOBACCO TREATED TOBACCO 

Curing procedures are as much an art as a science and each cure must be iudged on the basis of tobacco condition, interval between 

treatment and harvest, weather and type of curing facility before.prescription temperature and Ventilation schedules can be established. 

To obtain maximum quality, care must be taken to observe and control the curing process closely, especiaUy during the late "coloring" 

and early "drying' stages of the leaf. 

PAEpTM brand Ethephon for Cotton and Tobacco treated tobacco will have started the coloring process when harvested, reducing the 

time required in the coloring phase of curing. Treated tobacco should be dried faster. If tobacco leaves are green or contain some 

green when harvested, it may be necessary to color them for a few hours. If the leaves are completely yelloW, temperature and 

ventilation must be adjusted in a manner to dry the tobacco as fast as possible without scalding. Once the leaf is dried (314 dry), you 

should follow normal procedures tor curing. Since PREpM brand Ethephon for Cotton and Tobacco treated leaves cure faster, treated 

and untreated leaves should not be cured together in the same barn. 

8 
IMPORTANT: READ BEFORE USE 

Read the entire Directions for Use, Conditions, Disclaimer of Warranties and Limitations of Liability before using this product. If terms 

are not acceptable, return the unopened product container at once. 

By using this product, user or buyer accepts the following Conditions, Disclaimer of Warranties and Limitations of Liability. 

CONDITIONS: The directions for use of this product are believed to be adequate and must be followed carefully. However, it is 

impossible to eliminate all risks associated with the use of this product. Crop injury, ineffectiveness or other unintended consequences 

may result because of such factors as weather condiUons, presence of other materials, or the manner of use or application, all of which 

are beyond the control 01 Bayer CropScience. All such risks shall be assumed by the user or buyer. 

DISCLAIMER OF WARRANTIES: TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, BAYER CROPSCIENCE MAKES NO 

OTHER WARRANTIES, EXPRESS OR IMPLIED, OF MERCHANTABILITY OR OF FITNESS FOR A PARTICULAR PURPOSE OR 

OTHERWISE, THAT EXTEND BEYOND THE STATEMENTS MADE ON THIS LABEL No agent 01 Bayer CropScience is authorized to 

make any warranties beyond those contained herein or to modify the warranties contained herein. TO THE EXTENT CONSISTENT 

WITH APPLICABLE LAW, BAYER CROPSCIENCE DISCLAIMS ANY LIABILITY WHATSOEVER FOR SPECIAL, INCIDENTAL OR 

CONSEQUENTIAL DAMAGES RESUlTING FROM THE USE OR HANDLING OF THIS PRODUCT. 

LIMITATIONS OF LIABILITY: TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, THE EXCLUSIVE REMEDY OF THE 

USER OR BUYER FOR ANY AND AlL LOSSES, INJURIES OR DAMAGES RESULTING FROM THE USE OR HANDLING OF THIS 

PRODUCT, WHETHER IN CONTPACT, WARIW-ITY, TORT, NEGUG8\'CE, STRICT lJABflfTY OR OTHERWISE, SI-W.L NOT EXCEED THE 

PURCHASE PRICE PAID, OR AT BAYER CROPSCIENCE'S ELEC'TlOO, THE REPlACBllf8IJT0F PRODUCT. 

NET CONTENTS: 2.5 GALLONS 

Dropp, Ginstar, Def and Guihion are registered trademarks and Prep and Ultra are trademarks of Bayer. 

Folex is a registered trademark of Amvac Chemical Corporation. 

Harvade is a registered trademark 01 Uniroyal Company. 

Malathion is a trademark 01 American Cyanamid Company. 

~ Bayer Crop Science 

Bayer CropScience LP 

P.O. Box 12014,2 T.W. Alexander Drive 

Research Triangle Park, North Carolina 27709 

1~866~99BA YER (l~866~992-2937) 

PREpTM brand Ethephon lor Cotton and Tobacco (MASTER) 11/09/2010, Notiffcation 03/14/2011 

9 

14

IMPORTANT: READ BEFORE USE 

Read the entire Directions for Use, Conditions, Disclaimer of Warranties and Limitations of Liability before using this product. If terms 

are not acceptable, return the unopened product container at once. 

By using this product, user or buyer accepts the following Conditions, Disclaimer of Warranties and Limitations of Liability. 

CONDITIONS: The directions for use of this product are believed to be adequate and must be followed carefully. However, it is 

impossible to eliminate all risks associated with the use of this product. Crop injury, ineffectiveness or other unintended consequences 

may result because of such factors as weather condiUons, presence of other materials, or the manner of use or application, all of which 

are beyond the control 01 Bayer CropScience. All such risks shall be assumed by the user or buyer. 

DISCLAIMER OF WARRANTIES: TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, BAYER CROPSCIENCE MAKES NO 

OTHER WARRANTIES, EXPRESS OR IMPLIED, OF MERCHANTABILITY OR OF FITNESS FOR A PARTICULAR PURPOSE OR 

OTHERWISE, THAT EXTEND BEYOND THE STATEMENTS MADE ON THIS LABEL No agent 01 Bayer CropScience is authorized to 

make any warranties beyond those contained herein or to modify the warranties contained herein. TO THE EXTENT CONSISTENT 

WITH APPLICABLE LAW, BAYER CROPSCIENCE DISCLAIMS ANY LIABILITY WHATSOEVER FOR SPECIAL, INCIDENTAL OR 

CONSEQUENTIAL DAMAGES RESUlTING FROM THE USE OR HANDLING OF THIS PRODUCT. 

LIMITATIONS OF LIABILITY: TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, THE EXCLUSIVE REMEDY OF THE 

USER OR BUYER FOR ANY AND AlL LOSSES, INJURIES OR DAMAGES RESULTING FROM THE USE OR HANDLING OF THIS 

PRODUCT, WHETHER IN CONTPACT, WARIW-ITY, TORT, NEGUG8\'CE, STRICT lJABflfTY OR OTHERWISE, SI-W.L NOT EXCEED THE 

PURCHASE PRICE PAID, OR AT BAYER CROPSCIENCE'S ELEC'TlOO, THE REPlACBllf8IJT0F PRODUCT. 

NET CONTENTS: 2.5 GALLONS 

Dropp, Ginstar, Def and Guihion are registered trademarks and Prep and Ultra are trademarks of Bayer. 

Folex is a registered trademark of Amvac Chemical Corporation. 

Harvade is a registered trademark 01 Uniroyal Company. 

Malathion is a trademark 01 American Cyanamid Company. 

~ Bayer Crop Science 

Bayer CropScience LP 

P.O. Box 12014,2 T.W. Alexander Drive 

Research Triangle Park, North Carolina 27709 

1~866~99BA YER (l~866~992-2937) 

PREpTM brand Ethephon lor Cotton and Tobacco (MASTER) 11/09/2010, Notiffcation 03/14/2011 

9 
Bayer Crop Science 

Document Processing Desk (DIST) 

Office of Pesticide Programs (7504P) 

Insecticide-Rodenticide Branch 

U.S. Environmental Protection Agency 

Room S-4900, One Potomac Yard 

2777 South Crystal Drive 

Arlington, VA 22202-4501 

Attention: Ms. Joanne S. Edwards 

\ 

Subject: Notice of Cancellation of Supplemental Distributor 

Registration 

Dear Ms. Edwards, 

This letter is to notify the Agency of cancellation of supplemental distributor 

registrations for Southern States Cooperative, Inc. and Goldkist, Inc as 

distributors of the Bayer CropScience product listed below. The Company 

Number for Southern States Cooperative is 7183 and the company number for 

Goldkist is 2269. This cancellation is effective immediately. 

SOUTHERN STATES PREP BRAND ETHEPHON FOR COTTON; 

EPA Reg. No. 264-418-7138 if".", - 3 ., 

GK PREP (BRAND ETHEPHON FOR COTTON AND TOBACCO: 

EPA Reg. No. 264-418-2269 

If you have any questions or need additional information regarding this matter, 

please do not hesitate to contact me at 919-549-2302 or via e-mail at 

laura.phelps@bayer.com. 

Sincerely, 

Laura Phelps 

Regulatory Affairs, Herbicides & PGRs 

Bayer CropScience 

May 4, 2011 

Bayer CropScience 

P. O. Box 12014 

2 TW Alexander Drive 

Research Triangle Park 

NC 27709 

Tel: 91954g·2000 

, , , , 

"" , , ),' 

. . " . ) , J , 

'" , 

" , 

, , , . > , , • 

15

Bayer Crop Science 

Document Processing Desk (DIST) 

Office of Pesticide Programs (7504P) 

Insecticide-Rodenticide Branch 

U.S. Environmental Protection Agency 

Room S-4900, One Potomac Yard 

2777 South Crystal Drive 

Arlington, VA 22202-4501 

Attention: Ms. Joanne S. Edwards 

\ 

Subject: Notice of Cancellation of Supplemental Distributor 

Registration 

Dear Ms. Edwards, 

This letter is to notify the Agency of cancellation of supplemental distributor 

registrations for Southern States Cooperative, Inc. and Goldkist, Inc as 

distributors of the Bayer CropScience product listed below. The Company 

Number for Southern States Cooperative is 7183 and the company number for 

Goldkist is 2269. This cancellation is effective immediately. 

SOUTHERN STATES PREP BRAND ETHEPHON FOR COTTON; 

EPA Reg. No. 264-418-7138 if".", - 3 ., 

GK PREP (BRAND ETHEPHON FOR COTTON AND TOBACCO: 

EPA Reg. No. 264-418-2269 

If you have any questions or need additional information regarding this matter, 

please do not hesitate to contact me at 919-549-2302 or via e-mail at 

laura.phelps@bayer.com. 

Sincerely, 

Laura Phelps 

Regulatory Affairs, Herbicides & PGRs 

Bayer CropScience 

B . 

A \ 

BAYER 

E ,. R 

May 4, 2011 

Bayer CropScience 

P. O. Box 12014 

2 TW Alexander Drive 

Research Triangle Park 

NC 27709 

Tel: 91954g·2000 

, , , , 

"" , , ),' 

. . " . ) , J , 

'" , 

" , 

, , , . > , , • 
Bayer Crop Science 

2 T. W. Alexander Drive 

RTP, NC 27709 

office: 919-549-2302 

mobil:919-352-8075 

email: laura.phelps@bayer.coIll 

c. c. Jim Paul 

Senior Product Manager 

Southern States Cooperative, Inc. 

6606 West Broad St 

Po Box 26234 

Richmond, VA 23260 

8 

A 

BAYER 

E 

R 

'" , ", , 

> , , '" 

, 'J , 

, '" 

16

Bayer Crop Science 

2 T. W. Alexander Drive 

RTP, NC 27709 

office: 919-549-2302 

mobil:919-352-8075 

email: laura.phelps@bayer.coIll 

c. c. Jim Paul 

Senior Product Manager 

Southern States Cooperative, Inc. 

6606 West Broad St 

Po Box 26234 

Richmond, VA 23260 

8 

A 

BAYER 

E 

R 

'" , ", , 

> , , '" 

, 'J , 

, '" 
Bayer Crop Science 

Document Processing Desk (DIST) 

Office of Pesticide Programs (7504P) 

Insecticide-Rodenticide Branch 

U.S. Environmental Protection Agency 

Room S-4900, One Potomac Yard 

2777 South Crystal Drive 

Arlington, VA 22202-4501 

Attention: Ms. Joanne S. Edwards 

Subject: Notice of Cancellation of Supplemental Distributor 

Registration 

Dear Ms. Edwards, 

This letter is to notify the Agency of cancellation of a supplemental distributor 

registration for Chern Nut, Inc. as a distributor of the Bayer CropScience 

product listed below. The Company Number for Chern Nut, Inc. is 37686. This 

cancellation is effective immediately. 

PREP BRAND ETHEPHON FOR COTTON AND TOBACCO; EPA 

Reg. No. 264-418-37686 -_ 

PREP BRAND ETHEPHON COTTON BOLL OPENER: EPA Reg. No. 

264-418-37686 _ ~ 

If you have any questions or need additional information regarding this matter, 

please do not hesitate to contact me at 919-549-2302 or via e-mail at 

laura.phelps@baver.com. 

Sincerely, 

Laura Phelps 

Regulatory Affairs, Herbicides & PGRs 

Bayer CropScience 

2 T. W. Alexander Drive 

RTP, NC 27709 

office: 919-549-2302 

mobil:919-352-8075 

email: laura.phelps@bayer.com 

May 3, 2011 

Bayer CropScience 

P. O. Box 12014 

2 TW Alexander Drive 

Research Triangle Park 

NC 27709 

Tel: 919549-2000 

") , 

) '" 

17

Bayer Crop Science 

Document Processing Desk (DIST) 

Office of Pesticide Programs (7504P) 

Insecticide-Rodenticide Branch 

U.S. Environmental Protection Agency 

Room S-4900, One Potomac Yard 

2777 South Crystal Drive 

Arlington, VA 22202-4501 

Attention: Ms. Joanne S. Edwards 

Subject: Notice of Cancellation of Supplemental Distributor 

Registration 

Dear Ms. Edwards, 

This letter is to notify the Agency of cancellation of a supplemental distributor 

registration for Chern Nut, Inc. as a distributor of the Bayer CropScience 

product listed below. The Company Number for Chern Nut, Inc. is 37686. This 

cancellation is effective immediately. 

PREP BRAND ETHEPHON FOR COTTON AND TOBACCO; EPA 

Reg. No. 264-418-37686 -_ 

PREP BRAND ETHEPHON COTTON BOLL OPENER: EPA Reg. No. 

264-418-37686 _ ~ 

If you have any questions or need additional information regarding this matter, 

please do not hesitate to contact me at 919-549-2302 or via e-mail at 

laura.phelps@baver.com. 

Sincerely, 

Laura Phelps 

Regulatory Affairs, Herbicides & PGRs 

Bayer CropScience 

2 T. W. Alexander Drive 

RTP, NC 27709 

office: 919-549-2302 

mobil:919-352-8075 

email: laura.phelps@bayer.com 

B \ A \ V

YER 

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May 3, 2011 

Bayer CropScience 

P. O. Box 12014 

2 TW Alexander Drive 

Research Triangle Park 

NC 27709 

Tel: 919549-2000 

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Bayer CropScience 

Document Processing Desk (DIST) 

Office o[Pesticide Programs (7504P) 

Insecticide-Rodenticide Branch 

U.S. Environmental Protection Agency 

Room S-4900, One Potomac Yard 

2777 South Crystal Drive 

Arlington, VA 22202-4501 

Attention: Ms. Joanne S. Edwards 

Subject: Notice of Cancellation of Supplemental Distributor 

Registration 

Dear Ms. Edwards, 

This letter is to notify the Agency of cancellation of supplemental distributor 

registrations for Puregro Company and Royster Clark, Inc as distributors of the 

Bayer CropScience product listed below. The Company Number for Puregro 

Company is 1202 and the company number for Royster Clark, Inc is 4904.This 

cancellation is effective immediately. 

Puregro Company: 264-418-1202 PREP BRAND ETHEPHON FOR 

COTTON AND TOBACCO 

Royster Clark, Inc: 264-418-4904 POP BRAND ETHEPHON FOR 

COTTON AND TOBACCO 

If you have any questions or need additional infonnation regarding this matter, 

please do not hesitate to contact me at 919-549-2302 or via e-mail at 

laura.phelps@bayer.com. 

Sincerely, 

Laura Phelps 

Regulatory Affairs, Herbicides & PGRs 

Bayer CropScience 

May 4, 2011 

Bayer CropScience 

P. O. Box 12014 

2 TW Alexander Drive 

Research Triangle Park 

NC27709 

Tel: 919549-2000 

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18

Bayer CropScience 

Document Processing Desk (DIST) 

Office o[Pesticide Programs (7504P) 

Insecticide-Rodenticide Branch 

U.S. Environmental Protection Agency 

Room S-4900, One Potomac Yard 

2777 South Crystal Drive 

Arlington, VA 22202-4501 

Attention: Ms. Joanne S. Edwards 

Subject: Notice of Cancellation of Supplemental Distributor 

Registration 

Dear Ms. Edwards, 

This letter is to notify the Agency of cancellation of supplemental distributor 

registrations for Puregro Company and Royster Clark, Inc as distributors of the 

Bayer CropScience product listed below. The Company Number for Puregro 

Company is 1202 and the company number for Royster Clark, Inc is 4904.This 

cancellation is effective immediately. 

Puregro Company: 264-418-1202 PREP BRAND ETHEPHON FOR 

COTTON AND TOBACCO 

Royster Clark, Inc: 264-418-4904 POP BRAND ETHEPHON FOR 

COTTON AND TOBACCO 

If you have any questions or need additional infonnation regarding this matter, 

please do not hesitate to contact me at 919-549-2302 or via e-mail at 

laura.phelps@bayer.com. 

Sincerely, 

Laura Phelps 

Regulatory Affairs, Herbicides & PGRs 

Bayer CropScience 

May 4, 2011 

Bayer CropScience 

P. O. Box 12014 

2 TW Alexander Drive 

Research Triangle Park 

NC27709 

Tel: 919549-2000 

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ayer Crop Science 

2 T. W. Alexander Drive 

RTP, NC 27709 

office: 919~549-2302 

mobil:919-352-8075 

email: laura.phelps@bayer.com 

c. c. Mark R. Trostle 

Global Director of Registrations & Regulatory Affairs 

Loveland Products, Inc. 

Crop Production Services, Inc. 

3005 Rocky Mountain Ave. 

Loveland, CO 80538 

13 

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ayer Crop Science 

2 T. W. Alexander Drive 

RTP, NC 27709 

office: 919~549-2302 

mobil:919-352-8075 

email: laura.phelps@bayer.com 

c. c. Mark R Trostle 

Global Director of Registrations & Regulatory Affairs 

Loveland Products, Inc. 

Crop Production Services, Inc. 

3005 Rocky Mountain Ave. 

Loveland, CO 80538 

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Bayer CropScience 

November 17, 2010 

Document Processing Desk (NOTlF) 

Registration Division (7505P) 

Office of Pesticide Programs 

U.S. Environmental Protection Agency 

One Potomac Yard (South Building) 

2777 S. Crystal Drive 

Arlington, VA 22202 

Attn: Me. Tony Kish (PM22) 

Subject: PREP Brand Ethephon, EPA Registration. No. 264-418 

Submission of Final Printed Label 

Dear Mr. Kish: 

Bayer CropScience is submitting two copies of the final printed label for 

PREP Brand Ethephon, EPA Registration. No. 264A18 in response to the 

Agency's letter dated November 9,2010. 

A completed EPA fonn 8570-1 accompanies this cover. Please contact me if 

you should have further questions. 

Sincerely, 

Laura Phelps 

Regulatory Affairs, Herbicides & PGRs 

Bayer CropScience 

2 T. W. Alexander Drive 

RTP, NC 27709 

office: 919-549-2302 

mobiI:919-352-8075 

email: laura.phelps@bayer.com 

B 

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BAYER 

E 

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Bayer CropScience 

P. O. Box 12014 

2. T. W. Alexander Drive 

Research Triangle Park, NC 27709 

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20

Bayer CropScience 

November 17, 2010 

Document Processing Desk (NOTlF) 

Registration Division (7505P) 

Office of Pesticide Programs 

U.S. Environmental Protection Agency 

One Potomac Yard (South Building) 

2777 S. Crystal Drive 

Arlington, VA 22202 

Attn: Mr. Tony Kish (PM22) 

Subject: PREP Brand Ethephon, EPA Registration. No. 264-418 

Submission of Final Printed Label 

Dear Mr. Kish: 

Bayer CropScience is submitting two copies of the final printed label for 

PREP Brand Ethephon, EPA Registration. No. 264A18 in response to the 

Agency's letter dated November 9,2010. 

A completed EPA fonn 8570-1 accompanies this cover. Please contact me if 

you should have further questions. 

Sincerely, 

Laura Phelps 

Regulatory Affairs, Herbicides & PGRs 

Bayer CropScience 

2 T. W. Alexander Drive 

RTP, NC 27709 

office: 919-549-2302 

mobiI:919-352-8075 

email: Iaura.phelps@bayer.com 

Bayer CropScience 

P. O. Box 12014 

2. T. W. Alexander Drive 

Research Triangle Park, NC 27709 

, , 

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PI_III ,..d itul ctJo on,.~.be •• "'-- F~A roved. OMB No. 2070-0080 

United Stet .. § Registration OPP Identifier Number 

&EPA Environmental Protection Agency Amendment 

Washington, DC 20460 X Other 

Application for Pesticide - Section I 

1. CompenvIProduct Number 2. EPA Product Menagar 3. Propol&d Cla .. lflcation 

264-41B Mr. Tony Kish 

DNone o Re,trict&d 4. CompanylPfOduct (NJlme) PM' 

PREP Brand Ethephon 22 

5. Nama ond Addre .. of Appflcont (lncludo ZIP C6del 6. Expedited Review. In accgrdance with FIFRA Sectlgn 31cH3) 

Bayer CropScience LP IbHiJ, mv product is similar gr identical in composition and labeling 

P. O. Box 12014; 2 T. w. Alexander Dr. tg: 

Research Trianqle Park, NC 27709 II EPA Reg. No. 

o Chflck H thi$ is. nllw addrl$$ Product Name 

Section - II 

0 Amendmant - Explain balow. 0 Final printed labele in r .. pon .. to Nov, 9, 2010 

Agenoy lattar dated 

0 Reeubml .. ion In raepon .. to Agancy letter deted 0 eMe Tooe Application. 

0 Notificetion· Explain balow. 0 Othar· Explain below. 

Explanation; UIM additional page(e} If necellary. (For laction I and Section II.) 

A final printed label is submitted for PREP Brand Ethephon registration as stipulated in the Agency's letter of November 9, 2010. 

Section - III 

1. Meterial Th~ Product WIll a. Packl\Jed In: 

Child-Ra.ltent Packaging Unit Packoging Watlr Soluble Packaging 2. Typi of Containar 

B:" Bv" a v .. ~r .. ·, PlOltiC N. N. Glall 

• Cert1fiC8tion must II ey"e No. plr If eYase No, per Pepar 

Unit Packaging Wat. containar Pockagl wgt contalnar Other ISpecify} be submitted 

I 

3. Location of NIt ContOntl Information 4. Siza(sl Rltail Container 5. Lacetion of Label Oilectienll 

0 o Container 

B OnL.bel 

Leblll On Labeling Iccompenying product 

6. Mannar in Which Labal il Affixed to Product 

~ UthOgraruh 0 Otlar 

Peper R uad 

Stlnci Id 

Section -IV , , ... _,. 

1. Conlact Point IComplettt iref1l8 dirfICrly bl1low for idenrirrcotion of i'nd;vlduttl to bl conracrlld, if nttc-=ary, to proCI$$ th~ /lPpHcltion.1 

N_ Titll Telaphone No. --!lMUII .. a Arel Coda) 

Laura Phelps Reg. Affa'irs Associate "'H ~ , , , 

- - Certific8tion , ., -

6, ':)a~a''''ppliCQtien 

I cartify that tha IItotement. I heve made on thi. form Ind all auachrnents tharato era true, occurata and compl"te.' Racah/od 

, ., I ecknowlotdg. that any knowingly falae or mialeading etetemant may be punilhabll bV fino or imprillonmen, er j' , ;t~1ampedJ 

blth undlr applicablo law, , '; 

2, Slgn.tula 3. Titla , , , > , 

Regulatory Affairs Associate , 

, > , , , , 4. TyPotd Neml 5. Date ,. , , 

Laura Phelps November 1 7, 2010 

EPA - - Form 8570-1 IRlv. 8-94) PleVlou, .dltlonl ere ob\lliete. Whhe • EPA m. Copy lorlglnal) Ylliow • Appllcllnt Copy 

21

) 

PI_III ,..d Iturnx:t/OtM on ,.~. b.rtn. tomlN"dl'Hl ""1m. F rm ADDroved. 01'118 No. 2070-0080 

Unlt"d Stat .. § Registration opp Identifi,r Number 

&EPA Environmental Protection Agency Amendment 

Washington, DC 20460 X Other 

Application for Pesticide - Section I 

1. Complov/Product NUmb,r 2. EPA Product Mlnaoar 3. PropoI&d CI" .. lflcetion 

264-418 Mr. Tony Kish 

DNone o R.,tricted 4. CompanvlPfOdl,/ct (NJlmI) PM' 

PREP Brand Ethephon 22 

5. Nama ond Addr ... of Appflcont (lncludo ZIP C6dal 6. Expedited Review. In accordance with FIFRA Sectlgn 31cH3) 

Bayer CropScience LP IbHiJ, mv product is similar or identical in composition and labeling 

P. O. Box 12014; 2 T. W. Alexander Dr. to: 

Research Trianqle Park, NC 27709 II EPA Reg. No. 

o Chflck H thi$ is. nllw addrus Product Name 

Section - II 

0 Amendment - Explain balow, 0 Final printed labele in rellpon .. to Nov. 9, 2010 

Agenoy lener dated 

0 Re,ubml .. ion In r"pon .. to Agency lenor deted 0 eMe Tooe Application. 

0 Notificetion· Explain below. 0 Other· Explain below. 

Explanation; UIM additional paga!e} If nece .. ery. (For lection I and Section II.) 

A final printed label is submitted for PREP Brand Ethephon registration as stipulated in the Agency's letter of November 9, 2010. 

Section - III 

1. Meterial Th~ Product WIll a. P"eke\J8d In: 

Child-Roai.tent Pack"glng Unit Packoging Wot.r Soluble Packeging 2. Type of Containar 

B:" Bv" a v .. ~r .. ·, Plo.tic N. N. Gle .. 

• Cert1fiC8tion must II eYe.e No. per If "Yese No. per Peper 

Unit Packeging Wat. conteinar Pocbge wgt contolner Other ISpecify} be submitted 

3. Locetion of Net Contonte Infonnotion 4. Siza!sl Retail Container 5. Lecetion of Lobel Oilectien' 

0 o Container 

B On Label 

Lebal On Labeling eccompenying product 

6. Manner in Which Label ie Affixed to Product 1= UthOgraruh 0 Otlar 

Paper Rued 

Stenci ed 

Section -IV -

".-,. - 1. Conlact Point IComplattt ir'f1I8 dirfICrly bl1low for idanrif'rcotion of i'nd;vldual to be conracr"d, if ntlc-=ary. to proCHll th~ "PPHcation.J 

N_ Titla Telephone No. --IIMM",a Ara' Code) 

Laura Phelps Reg. Affa'lrs Associate "'H ~ 

- -

, 

- , 

Certific8tion - " , 6. ':)a~a''''ppliCQtien 

I certify that the stotement. I heve mllde on thi. form end all attachments thareto ere true, occureta and compl"ta.' Raceh/od 

, I acknowlotdg. that any knowingly falee or misleading statemont O1I1Y be puniahabl, by fino or imprisonmen, er j' " , ;t~tampedJ bath undar applicablo I,w, , '; 

2. Slgnlltul8 3. Titla , , , > , 

Regulatory Affairs Associate , 

, > , , 

- , 4. TyPod Name 5. Date " , , 

laura Phelps November 1 7, 2010 

, . EPA Form 8570-1 IRev, 8-94) PIIIVlOUS edltione era ob$elate. Whh •• EPA m. Copy lorlglnal) Yellow· Appllcllnt Copy 
PRE P TM brand Ethephon FOR COnON AND TOBACCO 

For Commercial Use Or Agricultural Use Only. Not For Residential Use 

ACTIVE INGREDIENT: Ethephon (2-Chloroethyl) phosphonic acid* .......................................... , ....................•.......... 55.4% 

INERT INGREDIENTS: ..................•.....•...........•............................................................................................................ 44.6% 

*This product contains 6 pounds ethephon per galion. 

EPA Reg. No. 264·418 EPA Est. No. 264·PA·01 

KEEP OUT OF REACH OF CHILDREN 

DANGER PELIGRO 

Si usted no enfiende la etiqueta, bus que a alguien para que se la exp!ique a usted en delalle. 

(If you do not understand the label, Und someone to explain lito you in delaiL) 

For MEDICAL And TRANSPORTATION Emergencies ONLY Call 24 Hours A Day 1·800-334-7577 

For PRODUCT USE Information Call1·866-99BAYER (1-866-992-2937) 

The use of this product for a variety of plant growth regulation uses are protected by United States and foreign patents including 

U.S. Patent 4,240,819. No license is granted to use this product in countries other than the United States or for any use not 

contemplated by this label. Liability for patent infringement may result from use or sale of this product outside the United States. 

IF IN EVES: 

IF ON SKIN OR 

CLOTHING: 

IF SWALLOWED: 

FIRST AID 

• Hold eye open and rinse slowly and gent!y with water for 15·20 minutes. 

• Remove contact lenses, if present, after the tirst 5 minutes, then continue rinsing eye. 

• Caff a poison control center or doctor for treatment advice. 

• Take off contaminated c!othing. 

• Rinse skin immediately with plenty of water for t5-20 minutes. 

• Caff a poison control center or doctor for treatment advice. 

• ImmedIately carr a poison control center or doctor for treatment advice. 

• 

• 

Do not induce vomiting unless told to do so by a poison control center or doctor. 

Have person sip a glass of water iI able to swaffow. 

• Do not ive anvthina bv mouth to an unconscious person. 

For MEDICAL Emergencies Call 24 Hours A Day 1-800-334-7577. 

Have the product container or label with vou when ca!!ina a poison control center or doctor or aoina for treatment 

NOTE TO PHYSICIAN: Treat symptomaticaffy. Consideration should be given to the possibi!lty that overexposure to n'iateri~l; other 

than this product may have occurred. No specitic antidote is avaiJable. Probable mucosal damage may contraindicale the use of 

Qastric lavace • ~ ~,' • 

PRECAUTIONARY STATEMENTS 

DANGER 

HAZARDS TO HUMANS AND DOMESTIC ANIMALS 

CORROSIVE. Causes irreversible eye damage and skin bums. 

skin or on clothing. 

PERSONAL PROTECTIVE EQUIPMENT (PPE) 

, -, , 

.. Harmful it swaffowed or absorbed throup~ikir.'. Do not get"in eyes, on 

Applicators and other handlers must wear coverarrs over short-sleeved shirts and short pants, chemical resistant glove§: made of any 

waterprool material (such as Nitrile, Butyl, Neoprene andlor Barrier Laminate), chemical-resistant footwear plus sVi;R&; protective 

eye":,,ear, chemical-resistant ~9ftftlfE1imlTead exposure and chemical-resistant apron when cleaning equipment or mixing and 

load"9· In Accordance with FR Notice 82-2 

Based On Draft Labeling Dated 

~l~Sl __ 22

PRE P TM brand Ethephon FOR COnON AND TOBACCO 

For Commercial Use Or Agricultural Use Only. Not For Residential Use 

ACTIVE INGREDIENT: Ethephon (2-Chloroethyl) phosphonic acid* .......................................... , ....................•.......... 55.4% 

INERT INGREDIENTS: ..................•.....•...........•............................................................................................................ 44.6% 

*This product contains 6 pounds ethephon per galion. 

EPA Reg. No. 264·418 EPA Est. No. 264·PA·01 

KEEP OUT OF REACH OF CHILDREN 

DANGER PELIGRO 

Si usted no enfiende la etiqueta, bus que a alguien para que se la exp!ique a usted en delalle. 

(If you do not understand the label, Und someone to explain lito you in delaiL) 

For MEDICAL And TRANSPORTATION Emergencies ONLY Call 24 Hours A Day 1·800-334-7577 

For PRODUCT USE Information Call1·866-99BAYER (1-866-992-2937) 

The use of this product for a variety of plant growth regulation uses are protected by United States and foreign patents including 

U.S. Patent 4,240,819. No license is granted to use this product in countries other than the United States or for any use not 

contemplated by this label. Liability for patent infringement may result from use or sale of this product outside the United States. 

FIRST AID 

IF IN EVES: • Hold eye open and rinse slowly and gent!y with water for 15·20 minutes. 

• Remove contact lenses, if present, after the tirst 5 minutes, then continue rinsing eye. 

IF ON SKIN OR 

CLOTHING: 

IF SWALLOWED: 

• Can a poison control center or doctor for treatment advice. 

• Take off contaminated c!othing. 

• Rinse skin immediately with plenty of water for t5-20 minutes. 

• can a poison control center or doctor for treatment advice. 

• ImmedIately carr a poison control center or doctor for treatment advice. 

• Do not induce vomiting unless told to do so by a poison control center or doctor. 

• Have person sip a glass of water iI able to swanow. 

• Do not give anything by mouth to an unconscious person. 

For MEDICAL Emergencies Call 24 Hours A Day 1-800-334-7577. 

Have the product container or label with you when ca!!ing a poison control center or doctor or going for treatment 

NOTE TO PHYSICIAN: Treat symptomaticany. Consideration should be given to the possibi!lty that overexposure to n'iateri~l; other 

than this product may have occurred. No specitic antidote is avaHable. Probable mucosal damage may contraindicale the use of 

! gastric lavage • ~ ~,' • 

PRECAUTIONARY STATEMENTS 

DANGER , -, , HAZARDS TO HUMANS AND DOMESTIC ANIMALS .. CORROSIVE. Causes irreversible eye damage and skin bums. 

skin or on clothing. 

Harmful it swanowed or absorbed throup~ikir.'. Do not get"in eyes, on 

PERSONAL PROTECTIVE EQUIPMENT (PPE) 

Applicators and other handlers must wear coverarrs over short-sleeved shirts and short pants, chemical resistant glove§: made of any 

waterprool material (such as Nitrile, Butyl, Neoprene andlor Barrier Laminate), chemical-resistant footwear plus sVi;R&; protective 

eye":,,ear, chemical-resistant ~9ftftlfE1imlTead exposure and chemical-resistant apron when cleaning equipment or mixing and 

load"9· In Accordance with FR Notice 82-2 

Based On Draft Labeling Dated 

~""lSl,--__ 
) 

Discard clothing and other absorbent materials that have been drenched or heavily contaminated with this products concentrate. Do 

not reuse them. Follow manufacturers instructions for cleaning/maintaining PPE. If no such instructions for washables, use detergent 

and hoi water. Keep and wash PPE separately from other laundry. 

When handlers use closed systems, enclosed cabs, or aircraft in a manner thai meels the requirements lisled in the Worker Protection 

Standard (WPS) for agricultural pesticides [40 CFR 170.240 (d) (4-6)], the handler PPE requirements may be reduced or modified as 

specified in Ihe WPS. 

User Safety Recommendations 

Users should wash hands before eatlng, drinking, chewing gum, using tobacco or using the tollet. 

Users should remove clothing immediately if pesticide gets inside. Then wash body thoroughly and put on clean clothing. 

Users should remove PPE immediately after handling this product. As soon as possible, wash thoroughly and change into clean 

clothing. Wash the outside of gloves before removing. 

ENVIRONMENTAL HAZARDS 

Do not apply directly to water, or to areas where surface water is present or to intertidal areas below the mean high water mark. 

Do not contaminate water when disposing of equipment washwaters. 

Do not contaminate water used for irrigation or domestic purposes. 

SPRAY DRIFT 

Avoid spray drift. Do not apply when weather conditions may cause drift. Do not allow this product to drift on to non-target areas. Drift 

may result in illegal residues or injury to adjacent crops and vegetation, in the form of leaf yellowing and defoliation. To avoid spray 

drift, DO NOT apply aerially when wind speed is greater than 10 mph or during periods of temperature inversions. Use of larger droplet 

size will also reduce spray drift. 

AVOIDING SPRAY DRIFT AT THE APPLICATION SITE IS THE RESPONSIBILITY OF THE APPLICATOR. 

The interaction of many equipment-and-weather-related factors determine the potential for spray drift. The applicator is responsible for 

considering all these tactors when making decisions. 

The following drift management requirements must be followed to avoid Oil-target movement from aerial applications to agricultural field 

crops. These requirements do not apply to forestry applications, public health uses or to applications using dry formulallons. 

1. The distance of the outer most nozzles on the boom must not exceed 3/4 the length of the wingspan or rotor. 

2. Nozzles must always point backward parallel with the air stream and never be pOinted downwards more than 45 degrees. 

Where states have more stringent regulations, they should be obselVed. 

The applicator should be tamiliar with and take into account the information covered in the Aerial Drift Reduction AdviSOry below: 

AERIAL DRIFT REDUCTION ADVISORY 

[This section is adviSOry in nature and does not supersede the mandatory label requirements]. 

INFORMATION ON DROPLET SIZE 

The most effective way to reduce drift potential is to apply large droplets. The best drift management strategy is to apply Ihe largest 

droplets that provide sufficient coverage and control. Applying larger droplets reduces drift potential, but will not prevent drift if 

applications are made improperly, or under unfavorable environmental conditions (See Wind, Temperature and Humidity, and 

Temperature Inversions). 

CONTROLLING DROPLET SIZE 

Volume - Use high tlow rate nozzles to apply the highest practical spray volume. Nozzles with higher rated flows produce larger 

droplets. 

Pressure - Do not exceed the nozzle manufacturer's recommended pressures. For many nozzle types lower pressure produces larger 

droplets. When higher flow rates are needed, use higher !low rate nozzles instead of increasing pressure. 

Number of nozzles - Use the minimum number ot nozzles that provide uniform coverage. 

Nozzle Orientation - Orienting nozzles so that the spray is released parallel to the airstream produces larger droplets Ihan other 

orientations and is the recommended practice. Significant deflection from horizontal will reduce droplet size and increase drift potential. 

Nozzle Type - Use a nozzle type that is designed for the intended application. With most nozzle types, narrower spray angles produce 

larger droplets. Consider using low-drift nozzles. Solid stream nozzles oriented straight back produce the largest droplets and the 

lowest drift. 

BOOM lENGTH 

For some use pallerns, reducing the effective boom length to less than 3/4 of the wingspan or rotor length may further reduce drift 

without reducing swath width. 

APPLICATION HEtGHT 

Applications should not be made at a height greater than 10 feet above the top of the target plants unless a greater height is required 

for aircraft safety. Making applications at the lowest height that is safe reduces exposure of droplets to evaporation and wind. 

2 

23

Discard clothing and other absorbent materials that have been drenched or heavily contaminated with this products concentrate. Do 

not reuse them. Follow manufacturer's instructions for cleaning/maintaining PPE. If no such instructions for washables, use detergent 

and hot water. Keep and wash PPE separately from other laundry. 

When handlers use closed systems, enclosed cabs, or aircraft in a manner that meets the requirements listed in the Worker Protection 

Standard (WPS) for agricultural pesticides [40 CFR 170.240 (d) (4-6)], the handler PPE requirements may be reduced or modified as 

specified in Ihe WPS. 

User Safety Recommendations 

Users should wash hands before eating, drinking, chewing gum, using tobacco or using the toilet. 

Users should remove clothing immediately if pesticide gets inside. Then wash body thoroughly and put on clean clothing. 

Users should remove PPE immediately after handling this product. As soon as possible, wash thoroughly and change into clean 

clothing. Wash the outside of gloves before removing. 

ENVIRONMENTAL HAZARDS 

Do not apply directly to water, or to areas where surface water is present or to intertidal areas below the mean high water mark. 

Do not contaminate water when disposing of equipment washwaters. 

Do not contaminate water used for irrigation or domestic purposes. 

SPRAY DRIFT 

Avoid spray drift. Do not apply when weather conditions may cause drift. Do not allow this product to drift on to non-target areas. Drift 

may result in illegal residues or injury to adjacent crops and vegetation, in the form of leaf yellowing and defoliation. To avoid spray 

drift, DO NOT apply aerially when wind speed is greater than 10 mph or during periods of temperature inversions. Use of larger droplet 

size will also reduce spray drift. 

AVOIDING SPRAY DRIFT AT THE APPLICATION SITE IS THE RESPONSIBILITY OF THE APPLICATOR. 

The interaction of many equipment-and-weather-related factors determine the potential for spray drift. The applicator is responsible for 

considering all these tactors when making decisions. 

The following drift management requirements must be followed to avoid ott-target movement from aerial applications to agricultural field 

crops. These requirements do not apply to forestry applications, public health uses or to applications using dry formulations. 

1. The distance of the outer most nozzles on the boom must not exceed 3/4 the length of the wingspan or rotor. 

2. Nozzles must always point backward parallel with the air stream and never be pOinted downwards more than 45 degrees. 

Where states have more stringent regulations, they should be obselVed. 

The applicator should be tamiliar with and take into account the information covered in the Aerial Drift Reduction AdviSory below: 

AERIAL DRIFT REDUCTION ADVISORY 

[This section is advisory in nature and does not supersede the mandatory label requirements]. 

INFORMATION ON DROPLET SIZE 

The most effective way to reduce drift potential is to apply large droplets. The best drift management strategy is to apply Ihe largest 

droplets that provide sufficient coverage and control. Applying larger droplets reduces drift potential, but will not prevent drift if 

applications are made improperly, or under unfavorable environmental conditions (See Wind, Temperature and Humidity, and 

Temperature Inversions). 

CONTROLLING DROPLET SIZE 

Volume - Use high tlow rate nozzles to apply the highest practical spray volume. Nozzles with higher rated flows produce larger 

droplets. 

Pressure - Do not exceed the nozzle manufacturer's recommended pressures. For many nozzle types lower pressure produces larger 

droplets. When higher flow rates are needed, use higher tlow rate nozzles instead of increasing pressure. 

Number of nozzles - Use the minimum number ot nozzles that provide uniform coverage. 

Nozzle Orientation - Orienting nozzles so that the spray is released parallel to the airstream produces larger droplets Ihan other 

orientations and is the recommended practice. Significant deflection from horizontal will reduce droplet size and increase drift potential. 

Nozzle Type - Use a nozzle type that is designed for the intended application. With most nozzle types, narrower spray angles produce 

larger droplets. Consider using low-drift nozzles. Solid stream nozzles oriented straight back produce the largest droplets and the 

lowest drift. 

BOOM lENGTH 

For some use patterns, reducing the effective boom length to less than 3/4 of the wingspan or rotor length may further reduce drift 

without reducing swath width. 

APPLICATION HEtGHT 

Applications should not be made at a height greater than 10 feet above the top of the target plants unless a greater height is required 

for aircraft safety. Making applications at the lowest height that is safe reduces exposure of droplets to evaporation and wind. 

2 
SWATH ADJUSTMENT 

When applications are made with a crosswind, the swath will be displaced downwind. Therefore, on the up and downwind edges of the 

field, the applicator should compensate for this displacement by adjustfng the path of the aircratt upwind. Swath adjustment distance 

should increase, with increasing drift potential (higher wind, smaller drops, etc.). 

WIND 

Drift potential is lowest between wind speeds of 2 • 10 mph. However, many factors, including droplet size and equipment type 

determine drift potential at any given speed. Application should be avoided below 2 mph due to variable wind direction and high 

inversion potential. NOTE: Local terrain can influence wind patterns. Every applicator should be tamiliar with local wind patterns and 

how they affect spray drift. 

TEMPERATURE AND HUMIDITY 

When making applicatfons in low relative humidity, set up equipment to produce larger droplets to compensate for evaporation. Droplet 

evaporation is most severe when conditions are both hot and dry. 

TEMPERATURE INVERSIONS 

Applications should not occur during a temperature inversion because dr'ift potential is high. Temperature 'Inversions restrict vertical air 

mixing, which causes srnall suspended droplets to remain in a concentrated cloud. This cloud can move in unpredictable directions due 

to the light variable winds common during inversions. Temperature inversions are characterized by increasing temperatures with 

altitude and are common on nights with limited cloud cover and light to no wind. They begin to form as the sun sets and often continue 

into the moming. Their presence can be indicated by ground fog; however, if fog is not present, inversions can also be identified by the 

movement of smoke from a ground source or an aircraft smoke generator. Smoke that layers and moves laterally in a concentrated 

cloud (under low wind conditions) indicates an inversion, while smoke that moves upward and rapidly dissipates indicates good vertical 

air mixing. 

SENSITIVE AREAS 

The pesticide should only be applied when the potential for drill to adjaCent sensitive areas (e.g. residential areas, bodies ot water, 

known habitat for threatened or endangered species, non·target crops) is minimal (e.g. when wind is blowing away from the sensitive 

areas). 

USE PRECAUTIONS 

Do not apply PREpTM brand Ethephon for Collon and Tobacco through any type of irrigation system. 

Avoid spray driJtto nearby crops as th'ls product will cause modilications in plant growth. Plant injury or reduced y'lelds will result. 

Mix only the amount oj spray you expect to use each day. Do not allow mixed solution to stand overnight. 

DIRECTIONS FOR USE 

It is a violation of Federal law to use this product in a manner inconsistent with its labeling. 

Do not apply this product in a way that will contact workers or olher persons, either directly or through dritt. Only protected handlers 

may be in the area during application. For any requirements specific to your State or Tribe, consult the agency responsible for pesticide 

regulations. Read entire label before using this prodUCt. 

AGRICULTURAL USE REQUIREMENTS 

Use this product only in accordance with its labeling and with the Worker Protection Standard, 40 CFR part 170. This standard contains 

requiremenls for the protection ot agricultural workers on fanns, forests, nurseries, and greenhouses, and handlers of agricultural 

pesticides. It contains requirements for training, decontamination, notification. and emergency assistance. It also contains specitic 

instructions and exceptfons pertaining to the statements on this label about personal proteclive equipment (PPE), notitication to workers 

and restricted'entry intervals. The requirements in this box only apply to uses otthis product that are covered by the Worker Protection 

Standard. 

Do not enter or allow worker entry into treated areas during the restricted-entry interval (REI) of 48 hours. The REI is 72 hours in areas 

where average rainfall is less than 25 inches per year. 

PPE required tor early entry to treated areas that is permitted under the Worker Protection Standard and that involves contact with 

anything that has been treated such as plants, soil or water is coveralls over long-sleeved shirt and long pants, chemical resistant 

gloves made of any waterproot material, such as nitrile, butyl, neoprene, or barrier laminate, chemical resistant footwear plus socks, 

and protective eyewear. For overhead exposure, chemical-resistant headgear is also required. 

Notify workers otthe application by waming them orally and posting warning signs at entrances to treated areas. 

3 

24

SWATH ADJUSTMENT 

When applications are made with a crosswind, the swath will be displaced downwind. Therefore, on the up and downwind edges of the 

field, the applicator should compensate for this displacement by adjustfng the path of the aircratt upwind. Swath adjustment distance 

should increase, with increasing drift potential (higher wind, smaller drops, etc.). 

WIND 

Drift potential is lowest between wind speeds of 2 • 10 mph. However, many factors, including droplet size and equipment type 

determine drift potential at any given speed. Application should be avoided below 2 mph due to variable wind direction and high 

inversion potential. NOTE: Local terrain can influence wind patterns. Every applicator should be tamiliar with local wind patterns and 

how they affect spray drift. 

TEMPERATURE AND HUMIDITY 

When making applicatfons in low relative humidity, set up equipment to produce larger droplets to compensate for evaporation. Droplet 

evaporation is most severe when conditions are both hot and dry. 

TEMPERATURE INVERSIONS 

Applications should not occur during a temperature inversion because dr'ift potential is high. Temperature 'Inversions restrict vertical air 

mixing, which causes srnall suspended droplets to remain in a concentrated cloud. This cloud can move in unpredictable directions due 

to the light variable winds common during inversions. Temperature inversions are characterized by increasing temperatures with 

altitude and are common on nights with limited cloud cover and light to no wind. They begin to form as the sun sets and often continue 

into the moming. Their presence can be indicated by ground fog; however, if fog is not present, inversions can also be identified by the 

movement of smoke from a ground source or an aircraft smoke generator. Smoke that layers and moves laterally in a concentrated 

cloud (under low wind conditions) indicates an inversion, while smoke that moves upward and rapidly dissipates indicates good vertical 

air mixing. 

SENSITIVE AREAS 

The pesticide should only be applied when the potential for drill to adjaCent sensitive areas (e.g. residential areas, bodies ot water, 

known habitat for threatened or endangered species, non·target crops) is minimal (e.g. when wind is blowing away from the sensitive 

areas). 

USE PRECAUTIONS 

Do not apply PREpTM brand Ethephon for Collon and Tobacco through any type of irrigation system. 

Avoid spray driJtto nearby crops as th'ls product will cause modilications in plant growth. Plant injury or reduced y'lelds will result. 

Mix only the amount oj spray you expect to use each day. Do not allow mixed solution to stand overnight. 

DIRECTIONS FOR USE 

It is a violation of Federal law to use this product in a manner inconsistent with its labeling. 

Do not apply this product in a way that will contact workers or olher persons, either directly or through dritt. Only protected handlers 

may be in the area during application. For any requirements specific to your State or Tribe, consult the agency responsible for pesticide 

regulations. Read entire label before using this prodUCt. 

AGRICULTURAL USE REQUIREMENTS 

Use this product only in accordance with its labeling and with the Worker Protection Standard, 40 CFR part 170. This standard contains 

requiremenls for the protection ot agricultural workers on fanns, forests, nurseries, and greenhouses, and handlers of agricultural 

pesticides. It contains requirements for training, decontamination, notification. and emergency assistance. It also contains specitic 

instructions and exceptfons pertaining to the statements on this label about personal proteclive equipment (PPE), notitication to workers 

and restricted'entry intervals. The requirements in this box only apply to uses otthis product that are covered by the Worker Protection 

Standard. 

Do not enter or allow worker entry into treated areas during the restricted-entry interval (REI) of 48 hours. The REI is 72 hours in areas 

where average rainfall is less than 25 inches per year. 

PPE required tor early entry to treated areas that is permitted under the Worker Protection Standard and that involves contact with 

anything that has been treated such as plants, soil or water is coveralls over long-sleeved shirt and long pants, chemical resistant 

gloves made of any waterproot material, such as nitrile, butyl, neoprene, or barrier laminate, chemical resistant footwear plus socks, 

and protective eyewear. For overhead exposure, chemical-resistant headgear is also required. 

Notify workers otthe application by waming them orally and posting warning signs at entrances to treated areas. 

3 
STORAGE AND DISPOSAL 

Do not contaminate water, food, or feed by storage or disposal. 

PESTICIDE STORAGE 

Store in a cool, dry place and away trom load, feed and other pesticides. IF SPILLED: If container is broken or contents have spilled, 

follow all precautions indicated above and clean up immediately. Belore cleaning up, put on ful! length trousers, long sleeved shirt, 

protective gloves, and goggles or face shield. Soak up spill with absorbent media such as sand, earth or other suitable material and 

dispose of wasle at an approved waste disposal facility. 

PESTICIDE DISPOSAL 

Pesticide wastes are acutely hazardous. Improper disposal of excess pestiCide, spray mixture, or rinsale is a violation 01 Federal law. If 

these wastes cannot be disposed of by use according to label instructions, contact your State Pesticide or Environmental Control 

Agency or the Hazardous Waste representative at the nearest EPA Regional Otfice for guidance. 

CONTAINER DISPOSAL 

Rigid, Non-refillable containers small enough to shake (i.e., with capacities equal to or less than 5 gallons) 

Non·refillable container. Do not reuse or refill this container. Triple rinse or pressure rinse container (or equivalent) promptly after 

emptying. Triple rinse as follows: Empty the remaining contents into application equipment or a mix tank and drain for to seconds after 

the How begins to drip. Fill the container 1/4 full with water and recap. Shake for 10 seconds. Pour rinsate into application equipment or 

a mix tank or store rinsate for later use or disposal. Drain for to seconds after the flow begins to drip. Repeat this procedure two more 

times. Once container is rinsed, offer for recycling if available or puncture and dispose of in a sanitary landtill. 

Rigid Non-refillable containers that are too large to shake (I.e., with capacities greater than 5 gallons or 50 Ibs) 

Non-reflllabfe Containers 

Non-retillable containers - Do not reuse or refill this container. Refer to Boltom Discharge IBC or Top Discharge IBC, Drums, Kegs 

information as follows. 

Bottom Discharge IBC (e.g. - Schuetz Caged IBC or Snyder Square Stackable) 

Pressure rinsing the container before final disposal is the responsibility otthe person disposing of the container. To pressure rinse the 

container before tinal disposal, empty the remaining contents from the IBC into application equipment or mix tank. Raise the bottom of 

the IBC by 1.5 inches on the side which is opposite of the boltom discharge valve to promote more complete product removal. 

Completely remove the top lid of the IBC. Use water pressurized to at least 40 PSI to rinse all interior portions. Continuously pump or 

drain rinsate into application equipment or rinsate collection system while pressure rinsing. Continue pressure rinsing for 2 minutes or 

until rinsate becomes clear. Replace the lid and close boltom valve. 

Top Discharge IBC, Drums, Kegs (e.g.- Snyder 120 Next Gen, Bonar 8120, Drums, Kegs). 

Triple rinSing the container before final disposal is the responsibility otthe person disposing of the container. To triple rinse the 

container before final disposal, empty the remaining contents from this container into application equipment or mix tank. Fill the 

container at least 1 ° percenttull with water. Agitate vigorously or recirculate water with the pump for 2 minutes. Rinse all interior 

surlaces. Pour or pump rinsate into application equipment or rinsate collection system. Repeat this procedure two more times. Once 

container is rinsed, offer for recycling if available or puncture and dispose ot in a sanitary landfill. 

Refillable Containers 

Retillable container - Refer to Bottom Discharge IBC or Top Discharge IBC, Drums, Kegs information as follows. Refill this container 

with pesticide only. Do not reuse this container for any other purpose. After emptying product from container, either retum container10 

Bayer CropScience per instructions from Bayer CropScience Customer Service Cell1er (1-800-527-4781) or rinse and either recycle or 

dispose oflhe container as follows: 

Bottom Discharge IBC (e.g. - Schuetz Caged IBC or Snyder Square Stackable) 

Pressure rinsing the container before tinal disposal is the responsibility of the person disposing of the container. Cleaning before refilling 

is the responsibility otthe refiller. To pressure rinse the container betore final disposal, empty the remaining contents from the IBC into 

application equipment or mix tank. Raise the bollom of the IBC by 1.5 inches on the side which is opposite of the bollom discharge 

valve to promote more complete product removal. Completely remove the top lid of the IBC. Use water pressurized to at least 40 PSI to 

rinse all interior portions. Continuously pump or drain rinsate into application equipment or rinsate coRection system while pressure 

rinsing. Continue pressure rinsing for 2 minutes or until rinsate becomes clear. Replace the lid and close bollom valve. 

Top Discharge IBC, Drums, Kegs (e.g.- Snyder 120 Next Gen, Bonar 8120, Drums, Kegs). 

Triple rinSing the container betore final disposal is the responsibility of the person disposing of the container. Cleaning betore retilling is 

the responsibility of the refmer. To triple rinse the containers betore final disposal, empty the remaining contents from this container into 

application equipment or mix tank. Fill the container at least 1 ° percent ful! with water. Agitate vigorously or recirculate water with the 

pump for 2 minutes. Rinse all interior surlaces. Pour or pump rinsate into application equipment or rinsate collection system. Repeat this 

procedure two more times. Once container is rinsed, oller tor recycling if available or puncture and dispose of in a sanitary landfill. 

4 

25

STORAGE AND DISPOSAL 

Do not contaminate water, food, or feed by storage or disposal. 

PESTICIDE STORAGE 

Store in a cool, dry place and away trom load, feed and other pesticides. IF SPILLED: If container is broken or contents have spilled, 

follow all precautions indicated above and clean up immediately. Belore cleaning up, put on ful! length trousers, long sleeved shirt, 

protective gloves, and goggles or face shield. Soak up spill with absorbent media such as sand, earth or other suitable material and 

dispose of wasle at an approved waste disposal facility. 

PESTICIDE DISPOSAL 

Pesticide wastes are acutely hazardous. Improper disposal of excess pestiCide, spray mixture, or rinsale is a violation 01 Federal law. If 

these wastes cannot be disposed of by use according to label instructions, contact your State Pesticide or Environmental Control 

Agency or the Hazardous Waste representative at the nearest EPA Regional Otfice for guidance. 

CONTAINER DISPOSAL 

Rigid, Non-refillable containers small enough to shake (i.e., with capacities equal to or less than 5 gallons) 

Non·refillable container. Do not reuse or refill this container. Triple rinse or pressure rinse container (or equivalent) promptly after 

emptying. Triple rinse as follows: Empty the remaining contents into application equipment or a mix tank and drain for to seconds after 

the How begins to drip. Fill the container 1/4 full with water and recap. Shake for 10 seconds. Pour rinsate into application equipment or 

a mix tank or store rinsate for later use or disposal. Drain for to seconds after the flow begins to drip. Repeat this procedure two more 

times. Once container is rinsed, offer for recycling if available or puncture and dispose of in a sanitary landtill. 

Rigid Non-refillable containers that are too large to shake (I.e., with capacities greater than 5 gallons or 50 Ibs) 

Non-reflllabfe Containers 

Non-retillable containers - Do not reuse or refill this container. Refer to Boltom Discharge IBC or Top Discharge IBC, Drums, Kegs 

information as follows. 

Bottom Discharge IBC (e.g. - Schuetz Caged IBC or Snyder Square Stackable) 

Pressure rinsing the container before final disposal is the responsibility otthe person disposing of the container. To pressure rinse the 

container before tinal disposal, empty the remaining contents from the IBC into application equipment or mix tank. Raise the bottom of 

the IBC by 1.5 inches on the side which is opposite of the boltom discharge valve to promote more complete product removal. 

Completely remove the top lid of the IBC. Use water pressurized to at least 40 PSI to rinse all interior portions. Continuously pump or 

drain rinsate into application equipment or rinsate collection system while pressure rinsing. Continue pressure rinsing for 2 minutes or 

until rinsate becomes clear. Replace the lid and close boltom valve. 

Top Discharge IBC, Drums, Kegs (e.g.- Snyder 120 Next Gen, Bonar 8120, Drums, Kegs). 

Triple rinSing the container before final disposal is the responsibility otthe person disposing of the container. To triple rinse the 

container before final disposal, empty the remaining contents from this container into application equipment or mix tank. Fill the 

container at least 1 ° percenttull with water. Agitate vigorously or recirculate water with the pump for 2 minutes. Rinse all interior 

surlaces. Pour or pump rinsate into application equipment or rinsate collection system. Repeat this procedure two more times. Once 

container is rinsed, offer for recycling if available or puncture and dispose ot in a sanitary landfill. 

Refillable Containers 

Retillable container - Refer to Bottom Discharge IBC or Top Discharge IBC, Drums, Kegs information as follows. Refill this container 

with pesticide only. Do not reuse this container for any other purpose. After emptying product from container, either retum container10 

Bayer CropScience per instructions from Bayer CropScience Customer Service Cell1er (1-800-527-4781) or rinse and either recycle or 

dispose oflhe container as follows: 

Bottom Discharge IBC (e.g. - Schuetz Caged IBC or Snyder Square Stackable) 

Pressure rinsing the container before tinal disposal is the responsibility of the person disposing of the container. Cleaning before refilling 

is the responsibility otthe refiller. To pressure rinse the container betore final disposal, empty the remaining contents from the IBC into 

application equipment or mix tank. Raise the bollom of the IBC by 1.5 inches on the side which is opposite of the bollom discharge 

valve to promote more complete product removal. Completely remove the top lid of the IBC. Use water pressurized to at least 40 PSI to 

rinse all interior portions. Continuously pump or drain rinsate into application equipment or rinsate coRection system while pressure 

rinsing. Continue pressure rinsing for 2 minutes or until rinsate becomes clear. Replace the lid and close bollom valve. 

Top Discharge IBC, Drums, Kegs (e.g.- Snyder 120 Next Gen, Bonar 8120, Drums, Kegs). 

Triple rinSing the container betore final disposal is the responsibility of the person disposing of the container. Cleaning betore retilling is 

the responsibility of the refmer. To triple rinse the containers betore final disposal, empty the remaining contents from this container into 

application equipment or mix tank. Fill the container at least 1 ° percent ful! with water. Agitate vigorously or recirculate water with the 

pump for 2 minutes. Rinse all interior surlaces. Pour or pump rinsate into application equipment or rinsate collection system. Repeat this 

procedure two more times. Once container is rinsed, oller tor recycling if available or puncture and dispose of in a sanitary landfill. 

4 
ReflUable Containers 

End users are authorized to remove tamper evident cables as required to remove the product from the container unless the container is 

equipped with one way valves and refilling or returning is planned. If this is the case, end users are not authorized to remove tamper 

evident cables, one way valves or clean container. See Container Disposal instructions under Storage and Disposal. 

GENERAL INFORMATION 

conON 

A foliar spray of PREpTM brand Ethephon for Colton and Tobacco will accelerate opening ot mature unopened colton bolls and enhance 

defoliation which can result in earlier harvest with an increased recoverable yield. PREpTM brand Ethephon for Colton and Tobacoo 

treatment on colton allows increased elliciency from a once-over harvest. 

TOBACCO (FLUE·CURED): A foliar spray of PREpTM brand Ethephon for Colton and Tobacco promotes early, unitorm "yellowing" of 

mature tobacco. PREpTM brand Ethephon for Cotton and Tobacco reduces curing time, allowing more eftfcient use of curing bam 

space, and increased control over harvest schedules. 

SPRAY PREPARATION 

Add 112 to 3/4 of the required amount ot water to the spray tank. Start agitation. Add the required amount of PREpTM brand Ethephon 

for Cotton and Tobacco, and the remaining amount of water. Prepare only as much spray solution as can be used on the day of mixing, 

Do not allow spray solution to stand overnight. Do not spill the concentrated product on spray eqUipment, or any airplane paris. 

ANY SPILLS SHOULD BE RINSED IMMEDIATELY WITH PLENTY OF WATER. 

Use of a nurse tank is highly recommended for avoiding possible spills of concentrated formulation on spray equipment or any airplane 

parts, 

TANK MIXTURES WITH DEFOLIANTS AND INSECTICIDES 

PREpTM brand Ethephon tor Cotton and Tobacco is compatible with DEf=®, FOLEX®, Dropp®, Dropp® UltraTM, Ginstar®, Harvade®, 

Methyl Parathion, Guthion®, and MalathionTM, PREpTM brand Ethephon for Colton and Tobacco may be applied in sequence or as a 

tank mixture (DO NOT TANK MIX WITH DESICCANTS IF COTTON IS TO BE SPINDLE HARVESTED). Follow all applicable use 

precautions and rate per acre recommendations on labels ot products applied as tank mixtures or in sequence with PREP TM brand 

Ethephon for Colton and Tobacco. In some cases slight reducflon in boll opening response has been observed when tank mixes with 

defoliants were used. 

Good agitation in the spray tank is essential and a tank mixture should not be allowed to stand without agitation tor more than 5 to 10 

minutes. Read and observe all appropriate label use directions and precautions for the defoliants and insecticides used. 

NOTE: UNDER CERTAIN CONDITIONS, TANK MIXTURES OF PREpTM BRAND ETHEPHON FOR COTTON AND TOBACCO WITH 

DESICCANTS CONTAINING SODIUM CHLORATE COULD RESULT IN THE FORMATION OF HYPOCHLOROUS ACIDS WHICH 

ON HEATING WILL EMIT TOXIC CHLORIDE FUMES. 

DO NOT MIX PREpTM BRAND ETHEPHON FOR COTTON AND TOBACCO WITH AMMONIUM THIOSULFATE. SUCH TANK 

MIXTURES MAY RESULT IN FORMATION OF TOXIC FUMES. 

EQUIPMENT CLEANING 

Because of the acidic nature of this product, prolonged exposure to spray deposit will damage acrylic plastics, certain pa'lnts, and 

metals. 

Rinse thoroughly with a detergent and water all exposed acrylic plastic-type matenals (e.g., aircratt windshields), and painted surfaces 

within an hour after exposure to spray deposits. 

At the end of each day, rinse thoroughly with a detergent and water all the metal parts of the aircraft and the associated spray 

eqUipment exposed to the spray deposits. 

5 

26

ReflUable Containers 

End users are authorized to remove tamper evident cables as required to remove the product from the container unless the container is 

equipped with one way valves and refilling or returning is planned. If this is the case, end users are not authorized to remove tamper 

evident cables, one way valves or clean container. See Container Disposal instructions under Storage and Disposal. 

GENERAL INFORMATION 

conON 

A foliar spray of PREpTM brand Ethephon for Colton and Tobacco will accelerate opening ot mature unopened colton bolls and enhance 

defoliation which can result in earlier harvest with an increased recoverable yield. PREpTM brand Ethephon for Colton and Tobacoo 

treatment on colton allows increased elliciency from a once-over harvest. 

TOBACCO (FLUE·CURED): A foliar spray of PREpTM brand Ethephon for Colton and Tobacco promotes early, unitorm "yellowing" of 

mature tobacco. PREpTM brand Ethephon for Cotton and Tobacco reduces curing time, allowing more eftfcient use of curing bam 

space, and increased control over harvest schedules. 

SPRAY PREPARATION 

Add 112 to 3/4 of the required amount ot water to the spray tank. Start agitation. Add the required amount of PREpTM brand Ethephon 

for Cotton and Tobacco, and the remaining amount of water. Prepare only as much spray solution as can be used on the day of mixing, 

Do not allow spray solution to stand overnight. Do not spill the concentrated product on spray eqUipment, or any airplane paris. 

ANY SPILLS SHOULD BE RINSED IMMEDIATELY WITH PLENTY OF WATER. 

Use of a nurse tank is highly recommended for avoiding possible spills of concentrated formulation on spray equipment or any airplane 

parts, 

TANK MIXTURES WITH DEFOLIANTS AND INSECTICIDES 

PREpTM brand Ethephon tor Cotton and Tobacco is compatible with DEf=®, FOLEX®, Dropp®, Dropp® UltraTM, Ginstar®, Harvade®, 

Methyl Parathion, Guthion®, and MalathionTM, PREpTM brand Ethephon for Colton and Tobacco may be applied in sequence or as a 

tank mixture (DO NOT TANK MIX WITH DESICCANTS IF COTTON IS TO BE SPINDLE HARVESTED). Follow all applicable use 

precautions and rate per acre recommendations on labels ot products applied as tank mixtures or in sequence with PREP TM brand 

Ethephon for Colton and Tobacco. In some cases slight reducflon in boll opening response has been observed when tank mixes with 

defoliants were used. 

Good agitation in the spray tank is essential and a tank mixture should not be allowed to stand without agitation tor more than 5 to 10 

minutes. Read and observe all appropriate label use directions and precautions for the defoliants and insecticides used. 

NOTE: UNDER CERTAIN CONDITIONS, TANK MIXTURES OF PREpTM BRAND ETHEPHON FOR COTTON AND TOBACCO WITH 

DESICCANTS CONTAINING SODIUM CHLORATE COULD RESULT IN THE FORMATION OF HYPOCHLOROUS ACIDS WHICH 

ON HEATING WILL EMIT TOXIC CHLORIDE FUMES. 

DO NOT MIX PREpTM BRAND ETHEPHON FOR COTTON AND TOBACCO WITH AMMONIUM THIOSULFATE. SUCH TANK 

MIXTURES MAY RESULT IN FORMATION OF TOXIC FUMES. 

EQUIPMENT CLEANING 

Because of the acidic nature of this product, prolonged exposure to spray deposit will damage acrylic plastics, certain pa'lnts, and 

metals. 

Rinse thoroughly with a detergent and water all exposed acrylic plastic-type matenals (e.g., aircratt windshields), and painted surfaces 

within an hour after exposure to spray deposits. 

At the end of each day, rinse thoroughly with a detergent and water all the metal parts of the aircraft and the associated spray 

eqUipment exposed to the spray deposits. 

5 
COTTON 

US, EXPECTED PREP"" BRAND ONE GAllON MINIMUM SPRAY APPLICATION 

CONDITiONS ETHEPHON FOR PREP'" VOLUMES TiMING 

COTTON AND BRAND (GalsfA)* 

TOBACCO ETHEPHON 

RATE FOR COTTON 

AND 

TOBACCO 

TREATS 

PinlsfA LBSA.f. Acres Ground Air·· .. 

PREpTM brand Hoi and dry BO°F or t t/3 1.0 6 Apply when the number of 

ETHEPHON FOR higher mature unopened bolls is 

COTTON AND Dry and 75 10 80°F 2 1.5 4 sufficient to proouce the 

TOBACCO to 2 des'lred crop. See below for 

Boll Opener" Cool but above 65°F 2 2/3 2.0 3 lest 01 boll maturity. 

Treatment uniformly opens 0, bolls 710 14 days earlier. 

Rank cotlon 

PREP"" brand High soil moisture t/3 0.25 24 to 5 Apply 4 10 7 days prior to 

ETHEPHON FOR 0' PREpTM brand Ethephon for 

COTTON AND High fertility level Collon and Tobacco boll 

TOBACCO + FOlEx"' opening appfication. To be 0, used "' a sequential Defoliant Tank Mix'" Rank collon treatment with, not in place 

01 PREpTM brand Ethephon 

lor Callan and Tobacco boll 

openinQ treatment. 

PREP"" brard High soil moisture t/3 0.25 24 to 3 Apply 4 to 7 days prior to 

ETHEPHON FOR 0, PREpTM brand Ethephon tor 

COTTON AND High lertility level Callan and Tobacco boll 

TOBACCO + Dropp opening application. To be 

0' used as a sequential Deloliant Tank Mix'" Rank collon treatment with, not in place 

01 PAEpTM brand Ethephon 

for Cotton and Tobacco boll 

opening treatment. 

Pre-Conditioner 00, Hot, dry, above 2/3 0.5 t2 Apply 4 to 7 days prior to 

Defoliation 80°F t t/3 1.0 6 10 2 defoliant. Enhances top 

Cool, above 65°F crop detoliation reducing 

0, deterioration of bottom crop 

and allows 10' earlier 

Aank calion halVest. 

• For best performance, by ground or air application, choose equipment and spray volumes that will insure unilorm coverage 01 loliage 

and bolls . 

.. Pretreatment With Defofiams Prior to PREP'M brand Ethephon for Cotton and Tobacco Boll Opening Treatment: If the Calion is overly 

rank or laying down in the middles and good spray coverage of the boffs with PREpTM brand Ethephon tor Collon and Tobacco is 

diflicufl, a pretreatment with defoliants will be useful to improve boll coverage with PREpTM brand Ethephon for Colton and Tobacco. 

Use dosage rates at PREpTM brand Ethephon for Callan and Tobacco recommended for boll opening. Read and obselVe all 

appropriate label use directions and precautions for the detoliant used . 

... Can use up to tull label rate for each product. 

** •• In California and Arizona use a volume of no less than 5 gallons per acre for aerial applications. 

Boll Malurity 

A boll is mature when it is too hard to be dented when squeezed between thumb and fingers, too hard to be sliced with a sharp knife, 

and when the seed coat becomes light brown in color. 

Use limitations 

Do not exceed a maximum of 2.0 lb. elhephon active ingredient per acre per year through combined or repeated uses 01 any 

ethephon products. 

Boll Opening: Do not tank mix PREpTM brand Ethephon for Callan and Tobacco with a desiccant if the callan is to be spindle 

halVested. 

6 

27

COTTON 

US, EXPECTED PREP"" BRAND ONE GAllON MINIMUM SPRAY APPLICATION 

CONDITiONS ETHEPHON FOR PREP'" VOLUMES TiMING 

COTTON AND BRAND (GalsfA)* 

TOBACCO ETHEPHON 

RATE FOR COTTON 

AND 

TOBACCO 

TREATS 

PinlsfA LBSA.f. Acres Ground Air·· .. 

PREpTM brand Hoi and dry BO°F or t t/3 1.0 6 Apply when the number of 

ETHEPHON FOR higher mature unopened bolls is 

COTTON AND Dry and 75 10 80°F 2 1.5 4 sufficient to proouce the 

TOBACCO to 2 des'lred crop. See below for 

Boll Opener" Cool but above 65°F 2 2/3 2.0 3 lest 01 boll maturity. 

Treatment uniformly opens 0, bolls 710 14 days earlier. 

Rank cotlon 

PREP"" brand High soil moisture t/3 0.25 24 to 5 Apply 4 10 7 days prior to 

ETHEPHON FOR 0' PREpTM brand Ethephon for 

COTTON AND High fertility level Collon and Tobacco boll 

TOBACCO + FOlEx"' opening appfication. To be 0, used "' a sequential Defoliant Tank Mix'" Rank collon treatment with, not in place 

01 PREpTM brand Ethephon 

lor Callan and Tobacco boll 

ooenino treatment. 

PREP"" brard High soil moisture t/3 0.25 24 to 3 Apply 4 to 7 days prior to 

ETHEPHON FOR 0, PREpTM brand Ethephon tor 

COTTON AND High lertility level Callan and Tobacco boll 

TOBACCO + Dropp opening application. To be 

0' used as a sequential Deloliant Tank Mix'" Rank collon treatment with, not in place 

01 PAEpTM brand Ethephon 

for Cotton and Tobacco boll 

ooenino treatment. 

Pre-Conditioner 00, Hot, dry, above 2/3 0.5 t2 Apply 4 to 7 days prior to 

Defoliation 80°F t t/3 1.0 6 10 2 defoliant. Enhances top 

Cool, above 65°F crop detoliation reducing 

0, deterioration of bottom crop 

and allows 10' earlier 

Aank calion halVest. 

• For best performance, by ground or air application, choose equipment and spray volumes that will insure unilorm coverage 01 loliage 

and bolls . 

.. Pretreatment With Defofiams Prior to PREP'M brand Ethephon for Cotton and Tobacco Boll Opening Treatment: If the Calion is overly 

rank or laying down in the middles and good spray coverage of the boffs with PREpTM brand Ethephon tor Collon and Tobacco is 

diflicufl, a pretreatment with defoliants will be useful to improve boll coverage with PREpTM brand Ethephon for Colton and Tobacco. 

Use dosage rates at PREpTM brand Ethephon for Callan and Tobacco recommended for boll opening. Read and obselVe all 

appropriate label use directions and precautions for the detoliant used . 

... Can use up to tull label rate for each product. 

** •• In California and Arizona use a volume of no less than 5 gallons per acre for aerial applications. 

Boll Malurity 

A boll is mature when it is too hard to be dented when squeezed between thumb and fingers, too hard to be sliced with a sharp knife, 

and when the seed coat becomes light brown in color. 

Use limitations 

Do not exceed a maximum of 2.0 lb. elhephon active ingredient per acre per year through combined or repeated uses 01 any 

ethephon products. 

Boll Opening: Do not tank mix PREpTM brand Ethephon for Callan and Tobacco with a desiccant if the callan is to be spindle 

halVested. 

6 
Pre-Condition for Defoliation: Do not tank mix PREpTM brand Ethephon for Cotton and Tobacco with desiccants unless plant 

desiccation is required. Do not use a defoliant before there is sufficient mature unopened bans to produce the desired yield (see 

General Information section on how to test for boll maturity. 

DO NOT APPLY PREpTM BRAND ETHEPHON FOR COTTON AND TOBACCO IF RAIN IS EXPECTED WITHIN 6 HOURS. 

Rainfall within 6 hours of application may reduce product performance. 

Do not plant another crop within 30 days after treatment. Small grains planted earlier than 1 month or intercropped with the callan 

crop to which PREpTM brand Ethephon tor Cotton and Tobacco will be applied may only be used as cover crops and may not be 

harvested for food or feed. PREpTM brand Ethephon for Collon and Tobacco may cause yellowing and growth inhibition of treated 

small grains. 

WHEN TO HARVEST COnON 

Do not harvest cotlon sooner than 7 days after a treatment with PREpTM brand Ethephon tor Colton and Tobacco. 

Observe the treated crop and harvest when optimum boll opening has been reached. Too early harvest might reduce the tull advantage 

of the treatment and too late a harvest may result in reduced quality and loss of lint which will drop from the plant. 

TOBACCO 

(Flue-Cured Only) 

Minimum Spray 

PREpTM brand Volumes Gallonsl 

Crop Situation E thephon for Am Specific Oirections 

Callan and 

Tobacco 

Pints/Acre 

Directed Spray 1 1/3 50 Use drop nozzles. Choose TG or DC spray tips designed to apply 50 - 60 

Application gpa al 35-40 psi aod al tractor speed of 2·3 mph. U" 

2 nozzles per row; one on each side of the row dropped low enough to direct 

the spray to the leaves to be ripened and harvested. Thorough spray 

coverage is essential. With a directed spray, be sure to harvest all leaves 

with 20% or more yellowing. 

Over-The-Top t 1/3-2213 40 Treat only when leaves remaining on the stalk are mature. To ensure 

Application remaining leaves are mature, test spray several tobacco plants as described 

under the section 'Proper Time of Treatment." Use the lower rate in a 

normally mature crop when experience indicates that minimum ripening 

inducement is required. Use the higher rate when the crop is heavy and has 

a tendency to be more rank or when temperatures are lower than nonnal. 

Always test spray to determine if the tobacco is mature enough to respond 

to treatment with PREpTM brand Ethephon for Callan and Tobacco. 

Apply over-the-top PREpTM brand Ethephon for Collon and Tobacco spray 

as a fine mist using Ihree nozzles (one nozzle tip over the center of the 

plant, and one on each side) so all leaves are covered thoroughly, similar to 

the application pallern of systemic sucker control agents. Use a spray 

oressure of 40 to 60 psi. 

USE LIMITATIONS 

Do not apply PREpTM brand Ethephon tor Calion and Tobacco to immature leaves as this can result in unsatisfactory coloring, 

weight loss and reduced leat quality. 

Do not allow the crop to over ripen in the field after using PREpTM brand Ethephon for Cotton and Tobacco, since this may cause 

some reduction in yield and quality. 

Do not treat before anticipated major storm which could prevent harvest and result in crop loss. 

DO NOT APPLY PREpTM BRAND ETHEPHON FOR COTTON AND TOBACCO IF RAIN IS EXPECTED WITHIN 6 HOURS. 

Rainfall within 6 hours of application may reduce product performance. 

Do not use PREpTM brand Ethephon for Collon and Tobacco with additives other than recommended on this label. 

Do not plant another crop within 30 days after treatment. 

Do not exceed a maximum of 2 Ibs ethephon active ingredient per acre per year through repeated uses of any ethephon products. 

7 

28

Pre-Condition for Defoliation: Do not tank mix PREpTM brand Ethephon for Cotton and Tobacco with desiccants unless plant 

desiccation is required. Do not use a defoliant before there is sufficient mature unopened bans to produce the desired yield (see 

General Information section on how to test for boll maturity. 

DO NOT APPLY PREpTM BRAND ETHEPHON FOR COTTON AND TOBACCO IF RAIN IS EXPECTED WITHIN 6 HOURS. 

Rainfall within 6 hours of application may reduce product performance. 

Do not plant another crop within 30 days after treatment. Small grains planted earlier than 1 month or intercropped with the callan 

crop to which PREpTM brand Ethephon tor Cotton and Tobacco will be applied may only be used as cover crops and may not be 

harvested for food or feed. PREpTM brand Ethephon for Collon and Tobacco may cause yellowing and growth inhibition of treated 

small grains. 

WHEN TO HARVEST COnON 

Do not harvest cotlon sooner than 7 days after a treatment with PREpTM brand Ethephon tor Colton and Tobacco. 

Observe the treated crop and harvest when optimum boll opening has been reached. Too early harvest might reduce the tull advantage 

of the treatment and too late a harvest may result in reduced quality and loss of lint which will drop from the plant. 

Minimum Spray 

PREpTM brand Volumes Gallonsl 

Crop Situation E thephon for Am 

Callan and 

Tobacco 

Pints/Acre 

Directed Spray 1 1/3 50 

Application 

Over-The-Top t 1/3-2213 40 

Application 

USE LIMITATIONS 

TOBACCO 

(Flue-Cured Only) 

Specific Directions 

Use drop nozzles. Choose TG or DC spray tips designed to apply 50 - 60 

gpa al 35-40 psi aod al tractor speed of 2·3 mph. U" 

2 nozzles per row; one on each side of the row dropped low enough to direct 

the spray to the leaves to be ripened and harvested. Thorough spray 

coverage is essential. With a directed spray, be sure to harvest all leaves 

with 20% or more yellowing. 

Treat only when leaves remaining on the stalk are mature. To ensure 

remaining leaves are mature, test spray several tobacco plants as described 

under the section 'Proper Time of Treatment." Use the lower rate in a 

normally mature crop when experience indicates that minimum ripening 

inducement is required. Use the higher rate when the crop is heavy and has 

a tendency to be more rank or when temperatures are lower than nonnal. 

Always test spray to determine if the tobacco is mature enough to respond 

to treatment with PREpTM brand Ethephon for Callan and Tobacco. 

Apply over-the-top PREpTM brand Ethephon for Collon and Tobacco spray 

as a fine mist using Ihree nozzles (one nozzle tip over the center of the 

plant, and one on each side) so all leaves are covered thoroughly, similar to 

the application pallern of systemic sucker control agents. 

I oressure of 40 to 60 osi. 

Use a spray 

Do not apply PREpTM brand Ethephon tor Calion and Tobacco to immature leaves as this can result in unsatisfactory coloring, 

weight loss and reduced leat quality. 

Do not allow the crop to over ripen in the field after using PREpTM brand Ethephon for Cotton and Tobacco, since this may cause 

some reduction in yield and quality. 

Do not treat before anticipated major storm which could prevent harvest and result in crop loss. 

DO NOT APPLY PREpTM BRAND ETHEPHON FOR COTTON AND TOBACCO IF RAIN IS EXPECTED WITHIN 6 HOURS. 

Rainfall within 6 hours of application may reduce product performance. 

Do not use PREpTM brand Ethephon for Collon and Tobacco with additives other than recommended on this label. 

Do not plant another crop within 30 days after treatment. 

Do not exceed a maximum of 2 Ibs ethephon active ingredient per acre per year through repeated uses of any ethephon products. 

7 
APPL!CATJONTIMING 

Successtul results with PREpTM brand Ethephon for Cotton and Tobacco call for treatment when leaves are mature, not overly rank 

green when sprayed. To easily determine the proper treatment timing and the number of leaves per stalk ready tor harvest, test spray 

several plants in more than one location in each field and observe the response. Mature leaves will begin to yellow in 24 to 72 hours. 

Test leaves that fail to yellow in 72 hours are not mature and are not ready for PREpTM brand Ethephon for Cotton and Tobacco 

treatment. Wait a few days to permlt turther natural maturing, then make another test spray or "maturity" check. 

To avoid quality loss and or possible leaf drop, harvest any yellowed leaves prior to applicalion. Use lower rates under most conditions. 

Limit use of higher rates to cool (below 65°F at the time of treatment) slow ripening conditions. 

When you have contirmed the desired number ot leaves per plant that will color, you can determine the number of acres to treat in order 

to fill the barn. 

Prepare your test spray by mixing one teaspoon of PREpTM brand Ethephon for Cotton and Tobacco in 1 quart of water. Spray each 

test plant with about 1 oz. of this mixture, covering all leaves with a tine mist. PREpTM brand Ethephon for Cotton and Tobacco will not 

color immature sprayed leaves. 

WHEN TO HARVEST 

All mature, sprayed leaves wiIJ begin to color within 24 to 72 hours after PREpTM brand Ethephon for Cotton and Tobacco application. 

The yellowing process is weather dependent; cool wea1her will delay, while hot, sunny weather can speed up the process. Harvest 

treated tobacco when leaves have reached the desired color intensity. 

Harvest can commence 48 hours after PREpTM brand Ethephon for Cotton and Tobacco application. To determine harvest timing and 

avoid quality loss or leaf drop, closely monitor treated crop and weather conditions. 

CURING PREP'" BRAND ETHEPHON FOR COnaN ANO TOBACCOTREATEOTOBACCO 

Curing procedures are as much an art as a science and each Cljre must be judged on the basis of tobacco condition, interval between 

1reatment and harvest, weather and type of curing facility before prescription temperature and ventilation schedules can be established. 

To obtain maximum quality, care must be taken to observe and control the curing process closely, especially during the late "coloring" 

and early "drying" stages of the leal. 

PREpTM brand Ethephon for Collon and Tobacco treated tobacco will have started the coloring process when harvested, reducing the 

time required in the coloring phase ot curing. Treated tobacco should be dried faster. If tobacco leaves are green or contain some 

green when harvested, it may be necessary to color them for a tew hours. If the leaves are completely yellow, temperature and 

ventilation must be adjusted in a manner to dry the tobacco as fast as possible without scalding. Once the leaf is dried (3/4 dry), you 

should follow normal procedures tor curing. Since PREpTM brand Ethephon for Cotlon and Tobacco treated leaves cure taster, treated 

and untreated leaves should not be cured together in the same barn. 

8 

29

APPL!CATJONTIMING 

Successtul results with PREpTM brand Ethephon for Cotton and Tobacco call for treatment when leaves are mature, not overly rank 

green when sprayed. To easily determine the proper treatment timing and the number of leaves per stalk ready tor harvest, test spray 

several plants in more than one location in each field and observe the response. Mature leaves will begin to yellow in 24 to 72 hours. 

Test leaves that fail to yellow in 72 hours are not mature and are not ready for PREpTM brand Ethephon for Cotton and Tobacco 

treatment. Wait a few days to permlt turther natural maturing, then make another test spray or "maturity" check. 

To avoid quality loss and or possible leaf drop, harvest any yellowed leaves prior to applicalion. Use lower rates under most conditions. 

Limit use of higher rates to cool (below 65°F at the time of treatment) slow ripening conditions. 

When you have contirmed the desired number ot leaves per plant that will color, you can determine the number of acres to treat in order 

to fill the barn. 

Prepare your test spray by mixing one teaspoon of PREpTM brand Ethephon for Cotton and Tobacco in 1 quart of water. Spray each 

test plant with about 1 oz. of this mixture, covering all leaves with a tine mist. PREpTM brand Ethephon for Cotton and Tobacco will not 

color immature sprayed leaves. 

WHEN TO HARVEST 

All mature, sprayed leaves wiIJ begin to color within 24 to 72 hours after PREpTM brand Ethephon for Cotton and Tobacco application. 

The yellowing process is weather dependent; cool wea1her will delay, while hot, sunny weather can speed up the process. Harvest 

treated tobacco when leaves have reached the desired color intensity. 

Harvest can commence 48 hours after PREpTM brand Ethephon for Cotton and Tobacco application. To determine harvest timing and 

avoid quality loss or leaf drop, closely monitor treated crop and weather conditions. 

CURING PREP'" BRAND ETHEPHON FOR COnaN ANO TOBACCOTREATEOTOBACCO 

Curing procedures are as much an art as a science and each Cljre must be judged on the basis of tobacco condition, interval between 

1reatment and harvest, weather and type of curing facility before prescription temperature and ventilation schedules can be established. 

To obtain maximum quality, care must be taken to observe and control the curing process closely, especially during the late "coloring" 

and early "drying" stages of the leal. 

PREpTM brand Ethephon for Collon and Tobacco treated tobacco will have started the coloring process when harvested, reducing the 

time required in the coloring phase ot curing. Treated tobacco should be dried faster. If tobacco leaves are green or contain some 

green when harvested, it may be necessary to color them for a tew hours. If the leaves are completely yellow, temperature and 

ventilation must be adjusted in a manner to dry the tobacco as fast as possible without scalding. Once the leaf is dried (3/4 dry), you 

should follow normal procedures tor curing. Since PREpTM brand Ethephon for Cotlon and Tobacco treated leaves cure taster, treated 

and untreated leaves should not be cured together in the same barn. 

8 
IMPORTANT: READ BEFORE USE 

Read the entire Directions for Use, Conditions, Disclaimer of Warranties and Limitations of liability before using this product. It terms 

are not acceptable, relurn the unopened product container al once. 

By using this product, user or buyer accepts the following Conditions, Disclaimer 01 Warranties and limitations 01 Liability. 

CONDITIONS: The directions lor use of this product are believed to be adequate and must be followed carefully. However, it is 

impossible to eliminate all risks associated with the use of this product. Crop injury, ineffectiveness or other unintended consequences 

may result because of such faclors as weather condHions, presence of other maler'lals, or the manner of use or application, all of wh'lch 

are beyond the control of Bayer CropScience. All such risks shall be assumed by the user or buyer. 

DISCLAIMER OF WARRANTIES: TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, BAYER CROP SCIENCE MAKES NO 

OTHER WARRANTIES, EXPRESS OR IMPLIED, OF MERCHANTABILITY OR OF FITNESS FOR A PARTICULAR PURPOSE OR 

OTHERWISE, THAT EXTEND BEYOND THE STATEMENTS MADE ON THIS LABEL. No agent of Bayer CropScience is authorized to 

make any warranties beyond those contained herein or to modify the warranties contained herein. TO THE EXTENT CONSISTENT 

WITH APPLICABLE LAW, BAYER CROPSCIENCE DISCLAIMS ANY LIABILITY WHATSOEVER FOR SPECIAL, INCIDENTAL OR 

CONSEQUENTIAL DAMAGES RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT. 

LIMITATIONS OF LIABILITY: TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, THE EXCLUSIVE REMEDY OF THE 

USER OR BUYER FOR ANY AND ALL LOSSES, INJURIES OR DAMAGES RESULTING FROM THE USE OR HANDLING OF THIS 

PRODUCT, WHETHER IN CONTRACT, WIIRR.ANTY, TORT, NEGUGENCE, STRICT LIA9IUfY OR Oll-ERWISE, SI-Wl.. NOT EXCEED THE 

PURCHASE PRICE PAlD, OR AT SAYER CAOPSClENCE'S ELECllON, THE REPlACEMENT OF PRODUCT. 

NET CONTENTS: 2.5 GALLONS 

Dropp, Ginstar, Def and Guthion are registered trademarks and Prep and Ultra are trademarks ot Bayer. 

Folex is a registered trademark ot Amvac Chemical Corporation. 

Harvade is a registered trademark of Uniroyal Company. 

Malathion is a trademark ot American Cyanamid Company. 

{ajj Bayer CropScience 

Bayer CropScience lP 

P,O, Box 12014, 2 T.W. Alexander Drive 

Research Triangle Park. North Carolina 27709 

1·866·99BAYER (1-866-992-2937) 

PREpTM brand Ethephon for Cotton and Tobacco (MASTER) 11/09/20tO 

9 

30

IMPORTANT: READ BEFORE USE 

Read the entire Directions for Use, Conditions, Disclaimer of Warranties and Limitations of liability before using this product. It terms 

are not acceptable, relurn the unopened product container al once. 

By using this product, user or buyer accepts the following Conditions, Disclaimer 01 Warranties and limitations 01 Liability. 

CONDITIONS: The directions lor use of this product are believed to be adequate and must be followed carefully. However, it is 

impossible to eliminate all risks associated with the use of this product. Crop injury, ineffectiveness or other unintended consequences 

may result because of such faclors as weather condHions, presence of other maler'lals, or the manner of use or application, all of wh'lch 

are beyond the control of Bayer CropScience. All such risks shall be assumed by the user or buyer. 

DISCLAIMER OF WARRANTIES: TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, BAYER CROP SCIENCE MAKES NO 

OTHER WARRANTIES, EXPRESS OR IMPLIED, OF MERCHANTABILITY OR OF FITNESS FOR A PARTICULAR PURPOSE OR 

OTHERWISE, THAT EXTEND BEYOND THE STATEMENTS MADE ON THIS LABEL. No agent of Bayer CropScience is authorized to 

make any warranties beyond those contained herein or to modify the warranties contained herein. TO THE EXTENT CONSISTENT 

WITH APPLICABLE LAW, BAYER CROPSCIENCE DISCLAIMS ANY LIABILITY WHATSOEVER FOR SPECIAL, INCIDENTAL OR 

CONSEQUENTIAL DAMAGES RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT. 

LIMITATIONS OF LIABILITY: TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, THE EXCLUSIVE REMEDY OF THE 

USER OR BUYER FOR ANY AND ALL LOSSES, INJURIES OR DAMAGES RESULTING FROM THE USE OR HANDLING OF THIS 

PRODUCT, WHETHER IN CONTRACT, WIIRR.ANTY, TORT, NEGUGENCE, STRICT LIA9IUfY OR Oll-ERWISE, SI-Wl.. NOT EXCEED THE 

PURCHASE PRICE PAlD, OR AT SAYER CAOPSClENCE'S ELECllON, THE REPlACEMENT OF PRODUCT. 

NET CONTENTS: 2.5 GALLONS 

Dropp, Ginstar, Def and Guthion are registered trademarks and Prep and Ultra are trademarks ot Bayer. 

Folex is a registered trademark ot Amvac Chemical Corporation. 

Harvade is a registered trademark of Uniroyal Company. 

Malathion is a trademark ot American Cyanamid Company. 

{ajj Bayer CropScience 

Bayer CropScience lP 

P,O, Box 12014, 2 T.W. Alexander Drive 

Research Triangle Park. North Carolina 27709 

1·866·99BAYER (1-866-992-2937) 

PREpTM brand Ethephon for Cotton and Tobacco (MASTER) 11/09/20tO 

9 
PRE P TM brand Ethephon FOR COTTON AND TOBACCO 

for Commercial Use Or Agricultural Use Only. Not for Residential Use 

ACTIVE INGREDIENT: Ethephon (2~Chloroethyl) phosphonic acid* .......................................................................... 55.4% 

INERT INGREDIENTS: ................................................................................................................................................. 44.6% 

*This product contains 6 pounds ethephon per gallon. 

EPA Reg. No. 264-418 EPA Est. No. 264-PA-01 

KEEP OUT OF REACH OF CHILDREN 

DANGER PELIGRO 

Si usled no entiende la eliqueta, busque a alguien para que se Ja explique a usled en delalJe. 

(If you do not understand the label, lind someone to explain it to you in detail.) 

For MEDICAL And TRANSPORTATION Emergencies ONLY Call 24 Hours A Day 1-800-334·7577 

For PRODUCT USE Information Call1-866·99BAYER (1-866·992-2937) 

The use of this product for a variety of plant growth regulation uses are protected by United States and foreign patents including 

U.S. Patent 4,240,819. No license is granted to use this product in countries other than the United States or for any use not 

contemplated by this label. Liability tor patent infringement may result from use or sale of this product outside the United States. 

IF IN EYES: 

IF ON SKIN OR 

CLOTHING: 

IF SWALLOWEO: 

FIRST AID 

• Hold eye open and rinse slowly and gently with water for t5-20 minutes. 

• 

• 

Remove contact lenses, it present, atter the firstS minutes, then conlinue rinsing eye. 

Call a poison control center or doctor for treatment advice. 

• Take off contaminated clothing. 

• Rinse skin immediately with plenty of water for t5-20 minutes. 

• Call a_p_oison control center or doctor for treatment advice. 

• Immediately call a poison control center or doctor for treatment advice. 

• Do not induce vomiflng unless told to do so by a poison control center or doctor. 

• Have person sip a glass of water if able to swallow. 

• Do not give anything by mouth to an unconscious person. 

For MEDICAL Emergencies Call 24 Hours A Day '·800-334·7577. 

Have theproouC! conta'mer or label with'jou when calling a poison control center or doctor or going for treatment. 

NOTE TO PHYSICIAN: Treat symptomatically. Consideration should be given to the possibility that overexposure to mat"1ialG other 

than this product may have occurred. No specific antidote is available. Probable mucosal damage may contraindicate the use of 

gastric lavage : ~. , ~ 

PRECAUTIONARY STATEMENTS 

DANGER 

HAZARDS TO HUMANS AND DOMESTIC ANIMALS 

,~ , . 

, " 

• 

CORROSIVE. Causes irreversible eye damage and skin burns. Harmful if swallowed or absorbed throt':::!h>!'Jdn. Do no~ ]ot·in eyes, on 

skin or on clothing. 

PERSONAL PROTECTIVE EQUIPMENT (PPE) , Applicators and other handlers must wear coveralls over short-sleeved shirts and short pants, chemical resistant glovPJ)J1ade of any 

waterproof material (such as Nitrile, Butyl, Neoprene and/or Barrier Laminate), chemical-resistant footwear plus s9f~St protective 

eyewear, chemical-resistant hea~! !,Q,r...5!Y.erhead exposure and Chemical-resistant apron when cleaning equipment or mixing and 

loading. NOT :t1J!;vlt;ww 

In Accordanoe Irtth PR Notice 82-2 

Based on Draft Labeling Dated 

\\\~ \\\) 

31

PRE P TM brand Ethephon FOR COTTON AND TOBACCO 

for Commercial Use Or Agricultural Use Only. Not for Residential Use 

ACTIVE INGREDIENT: Ethephon (2~Chloroethyl) phosphonic acid* .......................................................................... 55.4% 

INERT INGREDIENTS: ................................................................................................................................................. 44.6% 

*This product contains 6 pounds ethephon per gallon. 

EPA Reg. No. 264-418 EPA Est. No. 264-PA-01 

KEEP OUT OF REACH OF CHILDREN 

DANGER PELIGRO 

Si usled no entiende la eliqueta, busque a alguien para que se Ja explique a usled en delalJe. 

(If you do not understand the label, lind someone to explain it to you in detail.) 

For MEDICAL And TRANSPORTATION Emergencies ONLY Call 24 Hours A Day 1-800-334·7577 

For PRODUCT USE Information Call1-866·99BAYER (1-866·992-2937) 

The use of this product for a variety of plant growth regulation uses are protected by United States and foreign patents including 

U.S. Patent 4,240,819. No license is granted to use this product in countries other than the United States or for any use not 

contemplated by this label. Liability tor patent infringement may result from use or sale of this product outside the United States. 

IF IN EYES: 

IF ON SKIN OR 

CLOTHING: 

IF SWALLOWEO: 

FIRST AID 

• Hold eye open and rinse slowly and gently with water for t5-20 minutes. 

• Remove contact lenses, it present, atter the firstS minutes, then conlinue rinsing eye. 

• Call apoison control center or doctor for treatment advice. 

• Take off contaminated clothing. 

• Rinse skin immediately with plenty of water for t5-20 minutes. 

• Call a poison control center or doctor for treatment advice. 

• Immediately call a poison control center or doctor for treatment advice. 

• Do not induce vomiflng unless told to do so by a poison control center or doctor. 

• Have person sip a glass of water if able to swallow. 

• Do not aive anvthing ~mouth to an unconscious person. 

For MEDICAL Emergencies Call 24 Hours A Day '·800-334·7577. 

Have theproouct conta'mer or label wit!!~tou when callin~~_p()ison control center or doctor or aoino for treatment. 

NOTE TO PHYSICIAN: Treat symptomatically. Consideration should be given to the possibility that overexposure to mat"1ialG other 

than this product may have occurred. No specific antidote is available. Probable mucosal damage may contraindicate the use of 

, aastric lavaoe : ~. , ~ 

PRECAUTIONARY STATEMENTS 

DANGER 

HAZARDS TO HUMANS AND DOMESTIC ANIMALS 

,~ , . 

, " 

• 

CORROSIVE. Causes irreversible eye damage and skin burns. Harmful if swallowed or absorbed throt':::!h>!'Jdn. Do no~ ]ot,in eyes, on 

skin or on clothing. 

PERSONAL PROTECTIVE EQUIPMENT (PPE) , Applicators and other handlers must wear coveralls over short-sleeved shirts and short pants, chemical resistant glovPJ)J1ade of any 

waterproof material (such as Nitrile, Butyl, Neoprene and/or Barrier Laminate), chemical-resistant footwear plus s9f~St protective 

eyewear, chemical-resistant hea~! !,Q,r..5!Y.erhead exposure and Chemical-resistant apron when cleaning equipment or mixing and 

loading. NOT :t1J!;vlt;ww 

In Accordanoe Irtth PR Notice 82-2 

Based on Draft Labeling Dated 

\\\~ \\\) 
} 

Discard clothing and other absorbent materials thai have been drenched or heavily contaminated with this products concentrate. Do 

not reuse them. Follow manufacturer's instructions for cleaning/maintaining PPE. If no such instructions for washables, use detergent 

and hoi water. Keep and wash PPE separately from other laundry. 

When handlers use closed systems, enclosed cabs, or aircraft in a manner thai meets the requirements listed in the Worker Protection 

Standard (WPS) lor agricultural pesticides [40 CFR 170.240' (d) (4-6)), the handler PPE requirements may be reduced or modified as 

specilied in the WPS. 

User Safety Recommendations 

Users should wash hands before eating, drinking, chewing gum, using tobacco or using the toilet. 

Users should remove clothing immediately if pesticide gets inside. Then wash body thoroughly and put on clean clothing. 

Users should remove PPE immediately aller handling this product. As soon as possible, wash thoroughly and change into clean 

clothing. Wash the outside of gloves before removing. 

ENVIRONMENTAL HAZARDS 

Do not apply directly to water, or to areas where surface water is present or to intertidal areas below the mean high water marie 

Do not contaminate water when disposing of equipment washwaters. 

Do not contaminate water used for irrigation or domestic purposes. 

SPRAY DRIFT 

Avoid spray drift. Do not apply when weather conditions may cause drill. Do not allow this product to drift on to non-target areas. Drift 

may result in megal residues or injury to adracent crops and vegetation, in the form of leat yellowing and defoliation. To avoid spray 

drift, DO NOT apply aerially when wind speed is greater than J 0 mph or during periods ottemperature inversions. Use of larger droplet 

size will also reduce spray drift. 

AVOIDING SPRAY DRIFT AT THE APPLICATION SITE IS THE RESPONSIBILITY OF THE APPLICATOR. 

The interaction of many equipment-and-weather-related tactors determine the potential for spray drift. The applicator is responsible for 

considering all these factors when making decisions. 

The following drift management requirements must be tollowed to avoid off-target movement from aerial applications to agricultural field 

crops. These requirements do not apply to forestry applications, public health uses or to applications using dry formulations. 

1. The distance of the outer most nozzles on the boom must not exceed 3/4 the length of the wingspan or rotor. 

2. Nozzles must always point backward parallel with the air stream and never be pointed downwards more than 45 degrees. 

Where states have more stringent regulations, they should be observed. 

The applicator should be familiar with and take into account the information covered in the Aerial Drill Reduction Advisory below: 

AERIAL DRIFT REDUCTION ADVISORY 

[This section is advisory in nature and does not supersede the mandatory label requirements]. 

INFORMATION ON DROPLET SIZE 

The most effective way to reduce drift potential is to apply large droplets. The best drift management strategy is to apply the largest 

droplets that provide sullicient coverage and control. Applying larger droplets reduces drill potential, but will not prevent drift if 

applications are made improperly, or under untavorable environmental conditions (See Wind, Temperature and Humidity, and 

Temperature Inversions). 

CONTROLLING DROPLET SIZE 

Volume - Use high tlow rate nozzles to apply the highest practical spray volume. Nozzles with higher rated tlows produce larger 

droplets. 

Pressure - Do not exceed the nozzle manufacturer's recommended pressures. For many nozzle types lower pressure produces larger 

droplets. When higher lIow rates are needed, use higher flow rate nozzles instead of increasing pressure. 

Number of nozzles - Use the minimum number of nozzles that provide uniform coverage. 

Nozzle Orientation - Orienting nozzles so that the spray is released parallel to the airstream produces larger droplets than other 

orientations and is the recommended practice. Significant dellection from horizontal will reduce droplet size and increase drill potential. 

Nozzle Type - Use a nozzle type that is designed tor the intended application. With most nozzle types, narrower spray angles produce 

larger droplets. Consider using low-drift nozzles. Solld stream nozzles oriented straight back produce the largest droplets and the 

lowest drift. 

BOOM LENGTH 

For some use pattems, reducing the effective boom length to less than 3/4 ot the wingspan or rotor length may further reduce drift 

without reducing swath width. 

APPLICATION HEIGHT 

Applications should not be made at a height greater than 10 feet above the top ot the target plants unless a greater height is required 

tor aircraft satety. Making applications at the lowest height that is safe reduces exposure of droplets to evaporation and wind. 

2 

32

) 

Discard clothing and other absorbent materials thai have been drenched or heavily contaminated with this products concentrate. Do 

not reuse them. Follow manufacturer's instructions for cleaning/maintaining PPE. If no such instructions for washables, use detergent 

and hoi water. Keep and wash PPE separately from other laundry. 

When handlers use closed systems, enclosed cabs, or aircraft in a manner thai meets the requirements listed in the Worker Protection 

Standard (WPS) lor agricultural pesticides [40 CFR 170.240' (d) (4-6)), the handler PPE requirements may be reduced or modified as 

specilied in the WPS. 

User Safety Recommendations 

Users should wash hands before eating, drinking, chewing gum, using tobacco or using the toilet. 

Users should remove clothing immediately if pesticide gets inside. Then wash body thoroughly and put on clean clothing. 

Users should remove PPE immediately aller handling this product. As soon as possible, wash thoroughly and change into clean 

clothing. Wash the outside of gloves before removing. 

ENVIRONMENTAL HAZARDS 

Do not apply directly to water, or to areas where surface water is present or to intertidal areas below the mean high water marie 

Do not contaminate water when disposing of equipment washwaters. 

Do not contaminate water used for irrigation or domestic purposes. 

SPRAY DRIFT 

Avoid spray drift. Do not apply when weather conditions may cause drill. Do not allow this product to drift on to non-target areas. Drift 

may result in megal residues or injury to adracent crops and vegetation, in the form of leat yellowing and defoliation. To avoid spray 

drift, DO NOT apply aerially when wind speed is greater than J 0 mph or during periods ottemperature inversions. Use of larger droplet 

size will also reduce spray drift. 

AVOIDING SPRAY DRIFT AT THE APPLICATION SITE IS THE RESPONSIBILITY OF THE APPLICATOR. 

The interaction of many equipment-and-weather-related tactors determine the potential for spray drift. The applicator is responsible for 

considering all these factors when making decisions. 

The following drift management requirements must be tollowed to avoid off-target movement from aerial applications to agricultural field 

crops. These requirements do not apply to forestry applications, public health uses or to applications using dry formulations. 

1. The distance of the outer most nozzles on the boom must not exceed 3/4 the length of the wingspan or rotor. 

2. Nozzles must always point backward parallel with the air stream and never be pointed downwards more than 45 degrees. 

Where states have more stringent regulations, they should be observed. 

The applicator should be familiar with and take into account the information covered in the Aerial Drill Reduction Advisory below: 

AERIAL DRIFT REDUCTION ADVISORY 

[This section is advisory in nature and does not supersede the mandatory label requirements]. 

INFORMATION ON DROPLET SIZE 

The most effective way to reduce drift potential is to apply large droplets. The best drift management strategy is to apply the largest 

droplets that provide sullicient coverage and control. Applying larger droplets reduces drill potential, but will not prevent drift if 

applications are made improperly, or under untavorable environmental conditions (See Wind, Temperature and Humidity, and 

Temperature Inversions). 

CONTROLLING DROPLET SIZE 

Volume - Use high tlow rate nozzles to apply the highest practical spray volume. Nozzles with higher rated tlows produce larger 

droplets. 

Pressure - Do not exceed the nozzle manufacturer's recommended pressures. For many nozzle types lower pressure produces larger 

droplets. When higher lIow rates are needed, use higher flow rate nozzles instead of increasing pressure. 

Number of nozzles - Use the minimum number of nozzles that provide uniform coverage. 

Nozzle Orientation - Orienting nozzles so that the spray is released parallel to the airstream produces larger droplets than other 

orientations and is the recommended practice. Significant dellection from horizontal will reduce droplet size and increase drill potential. 

Nozzle Type - Use a nozzle type that is designed tor the intended application. With most nozzle types, narrower spray angles produce 

larger droplets. Consider using low-drift nozzles. Solld stream nozzles oriented straight back produce the largest droplets and the 

lowest drift. 

BOOM LENGTH 

For some use pattems, reducing the effective boom length to less than 3/4 ot the wingspan or rotor length may further reduce drift 

without reducing swath width. 

APPLICATION HEIGHT 

Applications should not be made at a height greater than 10 feet above the top ot the target plants unless a greater height is required 

tor aircraft satety. Making applications at the lowest height that is safe reduces exposure of droplets to evaporation and wind. 

2 
\ 

SWATH ADJUSTMENT 

When applications are made with a crosswind, the swath wi!! be displaced downwind. Therefore, on the up and downwind edges 01 the 

field, the applicator should compensate tor !his displacement by adjusting the path of the aircraft upwind. Swath adjustment distance 

should increase, with increasing drift potential (higher wind, smaller drops, etc.). 

WIND 

Drift potential is lowest between wind speeds of 2 • to mph. However, many factors, Including droplet size and equipment type 

determine drift potential at any given speed. Application should be avoided below 2 mph due to variable wind direction and high 

inversion potential. NOTE: Local terrain can intluence wind patterns. Every applicator should be familiar with local wind patterns and 

how they affect spray drift. 

TEMPERATURE AND HUMIDITY 

When making applications in low relative humidity, set up equipment to produce larger droplets to compensate for evaporation. Droplet 

evaporation is most severe when conditions are both hot and dry. 

TEMPERATURE INVERSIONS 

Applications should not occur during a temperature inversion because drift potenflal is h·lgh. Temperature inversions reslrict vertical air 

mixing, which causes small suspended droplets to remain in a concentrated cloud. This cloud can move in unpredictable directions due 

to the light variable winds common during inversions. Temperature inversions are characterized by increasing temperatures with 

altitude and are common on nights with limited cloud cover and light to no wind. They begin to form as the sun sets and often continue 

into the morning. Their presence can be indicated by ground tog; however, if fog is not present, inversions can also be identified by the 

movement 01 smoke from a ground source or an aircraft smoke generator. Smoke that layers and moves laterally in a concentrated 

cloud (under low wind conditions) indicates an inversion, while smoke that moves upward and rapidly dissipates indicates good vertical 

air mixing. 

SENSITIVE AREAS 

The pestiCide should only be applied when the potential for drift to adjacent sensitive areas (e.g. residential areas, bodies ot water, 

known habitat for threatened or endangered species, non-target crops) is minimal (e.g. when wind is blowing away from the sensitive 

areas). 

USE PRECAUTIONS 

Do not apply PREpTM brand Ethephon for Cotton and Tobacco through any type ot irrigation system. 

Avoid spray drift to nearby crops as this product will cause moditications in plant growth. Plant injury or reduced yields will result. 

Mix only the amount of spray you expect to use each day. Do not allow mixed solution to stand overnight. 

DIRECTIONS FOR USE 

H is a violation of Federal lawto use this product in a manner inconsistent with its labeling. 

Do not apply Ihis product in a way that will contact workers or other persons, either directly or through drift. Only protected handlers 

may be in the area during application. For any requirements specitic to your State or Tribe, consult the agency responsible for pesticide 

regulations. Read entire label before using this product. 

AGRICULTURAL USE REQUIREMENTS 

Use this product only in accordance with its labeling and with the Worker Protection Standard, 40 CFR part 170. This standard contains 

requirements tor the protection of agricultural workers on larms, forests, nurseries, and greenhouses, and handlers of agricultural 

pesticides. It contains requirements for training, decontamination, notftication, and emergency assistance. It also contains specific 

instructions and exceptions pertaining to the statements on this label about personal protective equipment (PPE), notification to workers 

and restricted-entry intervals. The requirements in this box only apply to uses of this product that are covered by the Worker Protection 

Standard. 

Do not enter or allow worker entry into treated areas during the restricted-entry interval (REI) of 48 hours. The REI is 72 hours in areas 

where average rainfall is less than 25 inches per year. 

PPE requ'lred lor early entry to treated areas that 'IS permitted under the Worker Protection Standard and that involves contact with 

anything that has been treated such as plants, soil or water is coveralls over long-sleeved shirt and long pants, chemical resistant 

gloves made of any waterproof material, such as nitrile, butyl, neoprene, or barrier laminate, chemical resistant footwear plus socks, 

and protective eyewear. For overhead exposure, chemical-resistant headgear is also required. 

Notify workers of the application by warning them orally and posting warning Signs at entrances to treated areas. 

3 

33

\ 

SWATH ADJUSTMENT 

When applications are made with a crosswind, the swath wi!! be displaced downwind. Therefore, on the up and downwind edges 01 the 

field, the applicator should compensate tor !his displacement by adjusting the path of the aircraft upwind. Swath adjustment distance 

should increase, with increasing drift potential (higher wind, smaller drops, etc.). 

WIND 

Drift potential is lowest between wind speeds of 2 • to mph. However, many factors, Including droplet size and equipment type 

determine drift potential at any given speed. Application should be avoided below 2 mph due to variable wind direction and high 

inversion potential. NOTE: Local terrain can intluence wind patterns. Every applicator should be familiar with local wind patterns and 

how they affect spray drift. 

TEMPERATURE AND HUMIDITY 

When making applications in low relative humidity, set up equipment to produce larger droplets to compensate for evaporation. Droplet 

evaporation is most severe when conditions are both hot and dry. 

TEMPERATURE INVERSIONS 

Applications should not occur during a temperature inversion because drift potenflal is h·lgh. Temperature inversions reslrict vertical air 

mixing, which causes small suspended droplets to remain in a concentrated cloud. This cloud can move in unpredictable directions due 

to the light variable winds common during inversions. Temperature inversions are characterized by increasing temperatures with 

altitude and are common on nights with limited cloud cover and light to no wind. They begin to form as the sun sets and often continue 

into the morning. Their presence can be indicated by ground tog; however, if fog is not present, inversions can also be identified by the 

movement 01 smoke from a ground source or an aircraft smoke generator. Smoke that layers and moves laterally in a concentrated 

cloud (under low wind conditions) indicates an inversion, while smoke that moves upward and rapidly dissipates indicates good vertical 

air mixing. 

SENSITIVE AREAS 

The pestiCide should only be applied when the potential for drift to adjacent sensitive areas (e.g. residential areas, bodies ot water, 

known habitat for threatened or endangered species, non-target crops) is minimal (e.g. when wind is blowing away from the sensitive 

areas). 

USE PRECAUTIONS 

Do not apply PREpTM brand Ethephon for Cotton and Tobacco through any type ot irrigation system. 

Avoid spray drift to nearby crops as this product will cause moditications in plant growth. Plant injury or reduced yields will result. 

Mix only the amount of spray you expect to use each day. Do not allow mixed solution to stand overnight. 

DIRECTIONS FOR USE 

H is a violation of Federal lawto use this product in a manner inconsistent with its labeling. 

Do not apply Ihis product in a way that will contact workers or other persons, either directly or through drift. Only protected handlers 

may be in the area during application. For any requirements specitic to your State or Tribe, consult the agency responsible for pesticide 

regulations. Read entire label before using this product. 

AGRICULTURAL USE REQUIREMENTS 

Use this product only in accordance with its labeling and with the Worker Protection Standard, 40 CFR part 170. This standard contains 

requirements tor the protection of agricultural workers on larms, forests, nurseries, and greenhouses, and handlers of agricultural 

pesticides. It contains requirements for training, decontamination, notftication, and emergency assistance. It also contains specific 

instructions and exceptions pertaining to the statements on this label about personal protective equipment (PPE), notification to workers 

and restricted-entry intervals. The requirements in this box only apply to uses of this product that are covered by the Worker Protection 

Standard. 

Do not enter or allow worker entry into treated areas during the restricted-entry interval (REI) of 48 hours. The REI is 72 hours in areas 

where average rainfall is less than 25 inches per year. 

PPE requ'lred lor early entry to treated areas that 'IS permitted under the Worker Protection Standard and that involves contact with 

anything that has been treated such as plants, soil or water is coveralls over long-sleeved shirt and long pants, chemical resistant 

gloves made of any waterproof material, such as nitrile, butyl, neoprene, or barrier laminate, chemical resistant footwear plus socks, 

and protective eyewear. For overhead exposure, chemical-resistant headgear is also required. 

Notify workers of the application by warning them orally and posting warning Signs at entrances to treated areas. 

3 
STORAGE AND DISPOSAL 

Do not conlam'lnate water, tood, or feed by storage or disposal. 

PESTICIDE STORAGE 

\ 

Store in a cool, dry place and away trom food, feed and other pesticides. IF SPILLED: It container is broken or contents have spilled, 

follow all precautlons indicated above and clean up immediately. Before cleaning up, put on full length trousers, long sleeved shirt, 

protective gloves, and goggles or face shield. Soak up spill with absorbent media such as sand, earth or other suitable material and 

dispose of waste at an approved waste disposal facility. 

PESTICIDE DISPOSAL 

Pesticide wastes are acutely hazardous, Improper disposal of excess pesticide, spray mixture, or rinsate is a violation of Federal law. If 

Ihese wastes cannot be disposed 01 by use according to label instructions, contact your State Pesticide or Environmental Control 

Agency or the Hazardous Waste representative at the nearest EPA Regional Ottice for guidance. 

CONTAINER DISPOSAL 

Rigid, Non-refillable containers small enough to shake (I.e., with capacities equal to or less than 5 gallons) 

Non-refillable container. Do not reuse or refill this container. Triple rinse or pressure rinse container (or equivalent) promptly after 

emptying. Triple rinse as follows: Empty the remaining contents into application equipment or a mix tank and drain for to seconds after 

the flow begins to drip. Fill the container 114 full with water and recap. Shake for to seconds. Pour nnsate into application equipment or 

a mix tank or store rinsate for later use or disposal. Drain for 10 seconds after the tlow begins to drip. Repeat this procedure two more 

times. Once container is rinsed, offer for recycling if available or puncture and d'ispose of in a sanital)' landtilr. 

Rigid Non-refmable containers that are too large to shake (I.e., with capacities greater than 5 gallons or 50 Ibs) 

Non-refillable Containers 

Non-retillable containers - Do not reuse or refill this container. Refer to Bottom Discharge IBC or Top Discharge IBC, Drums, Kegs 

intormation as tollows. 

Bottom Discharge IBe (e.g. - Schuetz Caged IBC or Snyder Square Stackable) 

Pressure rinsing the container before linal disposal is the responsibility 01 the person disposing ot the container. To pressure rinse the 

container before final disposal, empty the remaining contents from the IBC into appflcation equipment or mix tank. Raise the bottom ot 

the IBe by 1.5 inches on the side which is opposite of the bottom discharge valve to promote more complete product removal. 

Completely remove the top lid of the IBC. Use water pressurized to at least 40 PSI to rinse all interior portions. Continuously pump or 

drain rinsate inlo application eqUIpment or rinsate collection system while pressure rinsing. Continue pressure rinsing for 2 minutes or 

untif rinsate becomes clear. Replace the lid and close bottom valve. 

Top Discharge IBC, Drums, Kegs (e.g.- Snyder 120 Next Gen, Bonar B120, Drums, Kegs). 

Triple rinsing the container betore final disposal is the responsibility of the person disposing of the container. To triple rinse the 

container betore final disposal, empty the remaining contents trom this container into application equipment or mix tank. Fill the 

container at least to percent tull with water. Agitate vigorously or recirculate water with the pump tor 2 minutes. Rinse all interior 

surtaces. Pour or pump rinsate into application equipment or rinsate coHection system. Repeat this procedure two more times. Once 

container is rinsed, offer for recycling it avaifable or puncture and dispose of in a sanitary landtiff. 

Refillable Containers 

Retillable container- Refer to Bottom Discharge IBe or Top Discharge IBC, Drums, Kegs information as tollows. Refill this container 

with pesticide only. Do not reuse this container for any other purpose. After emptying product from container, either return container to 

Bayer CropScience per instructions from Bayer CropScience Customer Service Center (1-800-527-4781) or rinse and either recycle or 

dispose of the container as follows: 

Bottom Discharge fBC (e.g. - Schuetz Caged IBC or Snyder Square Stackable) 

Pressure rinsing the container before final disposal is the responsibility ot the person disposing of the container. Cleaning betore refilling 

is the responsibility of the retiller. To pressure rinse the container before tinal disposal, empty the remaining contents from the IBC into 

application equipment or mix tank. Raise the bottom of the IBC by 1.5 inches on the side which is opposite of the bottom discharge 

valve to promote more complete product removal. Completely remove the top lid of the IBC. Use water pressurized to at least 40 PSI to 

rinse all interior portions. Continuously pump or drain rinsate into application equipment or rinsate collection system while pressure 

rinSing. Continue pressure rinsing for 2 minutes or until rinsate becomes clear. Replace the lid and close bottom valve. 

Top Discharge IBC, Drums, Kegs (e.g.- Snyder 120 Next Gen, Bonar B120, Drums, Kegs). 

Triple rinsing the container betere final disposal is the responsibility of the person disposing of the container. Cleaning before refilling is 

the responsibility of the refiller. To triple rinse the containers betere tina! disposal, empty the remaining contents from this container into 

application equipment or mix tank. Fill the container at least 10 percent full with water. Agitate vigorously or recirculate water with the 

pump tor 2 minutes. Rinse all interior surtaces. Pour or pump rinsate into application equipment or rinsate collection system. Repeat this 

procedure two more times. Once container is rinsed, offer for recycling if available or puncture and dispose of in a sanitary landfill. 

4 

34

STORAGE AND DISPOSAL 

Do not conlam'lnate water, tood, or feed by storage or disposal. 

PESTICIDE STORAGE 

\ 

Store in a cool, dry place and away trom food, feed and other pesticides. IF SPILLED: It container is broken or contents have spilled, 

follow all precautlons indicated above and clean up immediately. Before cleaning up, put on full length trousers, long sleeved shirt, 

protective gloves, and goggles or face shield. Soak up spill with absorbent media such as sand, earth or other suitable material and 

dispose of waste at an approved waste disposal facility. 

PESTICIDE DISPOSAL 

Pesticide wastes are acutely hazardous, Improper disposal of excess pesticide, spray mixture, or rinsate is a violation of Federal law. If 

Ihese wastes cannot be disposed 01 by use according to label instructions, contact your State Pesticide or Environmental Control 

Agency or the Hazardous Waste representative at the nearest EPA Regional Ottice for guidance. 

CONTAINER DISPOSAL 

Rigid, Non-refillable containers small enough to shake (I.e., with capacities equal to or less than 5 gallons) 

Non-refillable container. Do not reuse or refill this container. Triple rinse or pressure rinse container (or equivalent) promptly after 

emptying. Triple rinse as follows: Empty the remaining contents into application equipment or a mix tank and drain for to seconds after 

the flow begins to drip. Fill the container 114 full with water and recap. Shake for to seconds. Pour nnsate into application equipment or 

a mix tank or store rinsate for later use or disposal. Drain for 10 seconds after the tlow begins to drip. Repeat this procedure two more 

times. Once container is rinsed, offer for recycling if available or puncture and d'ispose of in a sanital)' landtilr. 

Rigid Non-refmable containers that are too large to shake (I.e., with capacities greater than 5 gallons or 50 Ibs) 

Non-refillable Containers 

Non-retillable containers - Do not reuse or refill this container. Refer to Bottom Discharge IBC or Top Discharge IBC, Drums, Kegs 

intormation as tollows. 

Bottom Discharge IBe (e.g. - Schuetz Caged IBC or Snyder Square Stackable) 

Pressure rinsing the container before linal disposal is the responsibility 01 the person disposing ot the container. To pressure rinse the 

container before final disposal, empty the remaining contents from the IBC into appflcation equipment or mix tank. Raise the bottom ot 

the IBe by 1.5 inches on the side which is opposite of the bottom discharge valve to promote more complete product removal. 

Completely remove the top lid of the IBC. Use water pressurized to at least 40 PSI to rinse all interior portions. Continuously pump or 

drain rinsate inlo application eqUIpment or rinsate collection system while pressure rinsing. Continue pressure rinsing for 2 minutes or 

untif rinsate becomes clear. Replace the lid and close bottom valve. 

Top Discharge IBC, Drums, Kegs (e.g.- Snyder 120 Next Gen, Bonar B120, Drums, Kegs). 

Triple rinsing the container betore final disposal is the responsibility of the person disposing of the container. To triple rinse the 

container betore final disposal, empty the remaining contents trom this container into application equipment or mix tank. Fill the 

container at least to percent tull with water. Agitate vigorously or recirculate water with the pump tor 2 minutes. Rinse all interior 

surtaces. Pour or pump rinsate into application equipment or rinsate coHection system. Repeat this procedure two more times. Once 

container is rinsed, offer for recycling it avaifable or puncture and dispose of in a sanitary landtiff. 

Refillable Containers 

Retillable container- Refer to Bottom Discharge IBe or Top Discharge IBC, Drums, Kegs information as tollows. Refill this container 

with pesticide only. Do not reuse this container for any other purpose. After emptying product from container, either return container to 

Bayer CropScience per instructions from Bayer CropScience Customer Service Center (1-800-527-4781) or rinse and either recycle or 

dispose of the container as follows: 

Bottom Discharge fBC (e.g. - Schuetz Caged IBC or Snyder Square Stackable) 

Pressure rinsing the container before final disposal is the responsibility ot the person disposing of the container. Cleaning betore refilling 

is the responsibility of the retiller. To pressure rinse the container before tinal disposal, empty the remaining contents from the IBC into 

application equipment or mix tank. Raise the bottom of the IBC by 1.5 inches on the side which is opposite of the bottom discharge 

valve to promote more complete product removal. Completely remove the top lid of the IBC. Use water pressurized to at least 40 PSI to 

rinse all interior portions. Continuously pump or drain rinsate into application equipment or rinsate collection system while pressure 

rinSing. Continue pressure rinsing for 2 minutes or until rinsate becomes clear. Replace the lid and close bottom valve. 

Top Discharge IBC, Drums, Kegs (e.g.- Snyder 120 Next Gen, Bonar B120, Drums, Kegs). 

Triple rinsing the container betere final disposal is the responsibility of the person disposing of the container. Cleaning before refilling is 

the responsibility of the refiller. To triple rinse the containers betere tina! disposal, empty the remaining contents from this container into 

application equipment or mix tank. Fill the container at least 10 percent full with water. Agitate vigorously or recirculate water with the 

pump tor 2 minutes. Rinse all interior surtaces. Pour or pump rinsate into application equipment or rinsate collection system. Repeat this 

procedure two more times. Once container is rinsed, offer for recycling if available or puncture and dispose of in a sanitary landfill. 

4 
Refillable Containers 

End users are authorized to remove tamper evident cables as required to remove the product from the container unless the container is 

equipped with one way valves and refilling or returning is planned. If this is the case, end users are not authorized to remove tamper 

evident cables, one way valves or clean container. See Container Disposal instructions under Storage and Disposal. 

GENERAL INFORMATION 

conON 

A foliar spray of PREpTM brand Ethephon for Cotton and Tobacco will accelerate opening of mature unopened cotton bolls and enhance 

defoliation which can result in earlier harvest with an increased recoverable yield. PREpTM brand Ethephon for Cotton and Tobacoo 

treatment on cotton allows increased efficiency from a once-over harvest. 

TOBACCO (FLUE-CURED): A foliar spray of PREpTM brand Ethephon for Cotton and Tobacco promotes ear1y, uniform "yellowing' of 

mature tobacco. PREpTM brand Ethephon for Cotton and Tobacco reduces curing time, allowing more efficient use of curing bam 

space, and increased conlrol over harvest schedules. 

SPRAY PREPARATION 

Add 1/2 to 3/4 of the required amount of water to the spray tank. Start agitation. Add the required amount of PREpTM brand Ethephon 

for Cotton and Tobacco, and the remaining amount of water. Prepare only as much spray solution as can be used on the day of mixing. 

Do not allow spray solution to stand overnight. Do not spill the concentrated product on spray equipment, or any airplane parts. 

ANY SPILLS SHOULD BE RINSED IMMEDIATELY WITH PLENTY OF WATER. 

Use of a nurse tank is highly recommended for avoiding possible spills of concentrated formulation on spray equipment or any airplane 

parts. 

TANK MIXTURES WITH DEFOLIANTS AND INSECTIClDES 

PREpTM brand Ethephon for Cotton and Tobacco is compatible with DEpt>, FOLEX®, Dropp®, Dropp® Ultr'aTM, GinstarlID, Harvade®, 

Methyl Parathion, Guthion®, and MalathionTM. PREpTM brand Ethephon for Cotton and Tobacco may be applied in sequence or as a 

tank mixture (DO NOT TANK MIX WITH DESICCANTS IF COTTON IS TO BE SPINDLE HARVESTED). Follow all applicable use 

precautions and rate per acre recommendations on labels of products applied as tank mixtures or in sequence with PREP TM brand 

Ethephon for Cotton and Tobacco. In some cases slight reduction in boll opening response has been observed when tank mixes with 

defoliants were used. 

Good agitation in the spray tank is essential and a tank mixture should not be allowed to stand without agitation for more than 5 to to 

minutes. Read and observe all appropriate label use directions and precautions for the defoliants and insecticides used. 

NOTE: UNDER CERTAIN CONDITIONS, TANK MIXTURES OF PREpTM BRAND ETHEPHON FOR COTTON AND TOBACCO WITH 

DESICCANTS CONTAINING SODIUM CHLORATE COULD RESULT IN THE FORMATION OF HYPOCHLOROUS ACIDS WHICH 

ON HEATING WILL EMIT TOXIC CHLORIDE FUMES. 

DO NOT MIX PREpTM BRAND ETHEPHON FOR COTTON AND TOBACCO WITH AMMONIUM THIOSULFATE. SUCH TANK 

MIXTURES MAY RESULT IN FORMATION OF TOXIC FUMES. 

EQUIPMENT CLEANING 

Because of the acidic nature of this product, prolonged exposure to spray deposit will damage acrylic plastiCS, certain paints, and 

metals. 

Rinse thoroughly with a detergent and water all exposed acrylic plastic-type materials (e.g., aircraft windshields), and painted surfaces 

within an hour after exposure to spray deposits. 

At the end of each day, rinse thoroughly with a detergent and water all the metal parts of the aircraft and the associated spray 

equipment exposed to the spray deposits. 

5 

35

Refillable Containers 

End users are authorized to remove tamper evident cables as required to remove the product from the container unless the container is 

equipped with one way valves and refilling or returning is planned. If this is the case, end users are not authorized to remove tamper 

evident cables, one way valves or clean container. See Container Disposal instructions under Storage and Disposal. 

GENERAL INFORMATION 

conON 

A foliar spray of PREpTM brand Ethephon for Cotton and Tobacco will accelerate opening of mature unopened cotton bolls and enhance 

defoliation which can result in earlier harvest with an increased recoverable yield. PREpTM brand Ethephon for Cotton and Tobacoo 

treatment on cotton allows increased efficiency from a once-over harvest. 

TOBACCO (FLUE-CURED): A foliar spray of PREpTM brand Ethephon for Cotton and Tobacco promotes ear1y, uniform "yellowing' of 

mature tobacco. PREpTM brand Ethephon for Cotton and Tobacco reduces curing time, allowing more efficient use of curing bam 

space, and increased conlrol over harvest schedules. 

SPRAY PREPARATION 

Add 1/2 to 3/4 of the required amount of water to the spray tank. Start agitation. Add the required amount of PREpTM brand Ethephon 

for Cotton and Tobacco, and the remaining amount of water. Prepare only as much spray solution as can be used on the day of mixing. 

Do not allow spray solution to stand overnight. Do not spill the concentrated product on spray equipment, or any airplane parts. 

ANY SPILLS SHOULD BE RINSED IMMEDIATELY WITH PLENTY OF WATER. 

Use of a nurse tank is highly recommended for avoiding possible spills of concentrated formulation on spray equipment or any airplane 

parts. 

TANK MIXTURES WITH DEFOLIANTS AND INSECTIClDES 

PREpTM brand Ethephon for Cotton and Tobacco is compatible with DEpt>, FOLEX®, Dropp®, Dropp® Ultr'aTM, GinstarlID, Harvade®, 

Methyl Parathion, Guthion®, and MalathionTM. PREpTM brand Ethephon for Cotton and Tobacco may be applied in sequence or as a 

tank mixture (DO NOT TANK MIX WITH DESICCANTS IF COTTON IS TO BE SPINDLE HARVESTED). Follow all applicable use 

precautions and rate per acre recommendations on labels of products applied as tank mixtures or in sequence with PREP TM brand 

Ethephon for Cotton and Tobacco. In some cases slight reduction in boll opening response has been observed when tank mixes with 

defoliants were used. 

Good agitation in the spray tank is essential and a tank mixture should not be allowed to stand without agitation for more than 5 to to 

minutes. Read and observe all appropriate label use directions and precautions for the defoliants and insecticides used. 

NOTE: UNDER CERTAIN CONDITIONS, TANK MIXTURES OF PREpTM BRAND ETHEPHON FOR COTTON AND TOBACCO WITH 

DESICCANTS CONTAINING SODIUM CHLORATE COULD RESULT IN THE FORMATION OF HYPOCHLOROUS ACIDS WHICH 

ON HEATING WILL EMIT TOXIC CHLORIDE FUMES. 

DO NOT MIX PREpTM BRAND ETHEPHON FOR COTTON AND TOBACCO WITH AMMONIUM THIOSULFATE. SUCH TANK 

MIXTURES MAY RESULT IN FORMATION OF TOXIC FUMES. 

EQUIPMENT CLEANING 

Because of the acidic nature of this product, prolonged exposure to spray deposit will damage acrylic plastiCS, certain paints, and 

metals. 

Rinse thoroughly with a detergent and water all exposed acrylic plastic-type materials (e.g., aircraft windshields), and painted surfaces 

within an hour after exposure to spray deposits. 

At the end of each day, rinse thoroughly with a detergent and water all the metal parts of the aircraft and the associated spray 

equipment exposed to the spray deposits. 

5 
COTTON 

USE EXPECTED PREP"" BRAND ONE GALLON MINIMUM SPRAY APPLICATION 

CONDITIONS ETHEPHON FOR PREpTM VOLUMES TIMING 

COnONAND BRAND (Gals/A)' 

TOBACCO ETHEPHON 

RATE FOR COTTON 

AND 

TOBACCO 

TREATS 

PintsfA LBSAJ. Acres Ground Air'''' 

PREP"'" brand Hot and dry BOaF or t tl3 1.0 6 Apply when the number of 

ETHEPHON FOR higher mature unopened bolls is 

COTTON AND Dry and 75 to aO°F 2 1.5 4 sufficient 10 produce Ih, 

TOBACCO ID 2 desired crop, See below for 

Boll Opener" Cool but above 65°F 2213 2.0 3 I"" of boll maturity. 

Treatment unilormly opens 

or bolls 710 14 days earlier. 

Rank colton 

PREP'''' brand High soil moisture 1/3 0.25 24 10 5 Apply 4 to 7 days prior to 

ETHEPHON FOR or PREpTM brand Elhephon lor 

COnONAND High lertility level Cotlon "d Tobacco boll 

TOBACCO + FOlEX@ opening application, To be· 

or used os , sequential DefolianlTank Mix'" Rank cotton treatment with, not in place 

at PREpTM brand Ethephon 

for Callan am Tobacco boll 

opening treatment. 

PREP'''' brand High soil moisture 1/3 0.25 24 10 3 Apply 4 to 7 days prior to 

ETHEPHON FOR or PREpTM brand Ethephon for 

COnONAND High fertility level Cotlon "d Tobacco boll 

TOBACCO + Dropp opening application. To be 

or used " , sequential DefoliantTank Mix'" 

Rank cotton treatment with, not in place 

of PREpTM brand Ethephon 

for Collon and Tobacco boll 

opening treatment. 

Pre-Conditioner for Hot, dry, above 213 0.5 12 Apply 4 to 7 days prior to 

Defoliation BO°F 1 t/3 1.0 6 ID 2 defoliant. Enhances lop 

Cool, above 65°F crop defoliation reducing 

or 

deterioration of bottom crop 

and allows for earlier 

Rank cotton harvest. 

• For best pertormance, by ground or air application, choose equipment and spray volumes that will insure unilorm coverage of foliage 

and bolls . 

•• Pretreatment With Defoliants Prior to PREpThI brand Ethephon for Cotton and Tobacco Boll Opening Treatment: If the Callan is overly 

rank or laying down in the middles and good spray coverage of the bolls with PREpTM brand Ethephon for Calion and Tobacco is 

dillicull, a pretreatment with defoliants will be useful to improve boll coverage with PREpTM brand Ethephon tor Cotton and Tobacco. 

Use dosage rates of PREpTM brand Ethephon for Callan and Tobacco recommended for boll opening. Read and observe all 

appropriate label use directions and precauflons for Ihe defoliant used . 

• ** Can use up to full label rate for each product. 

.... In California and Arizona use a volume ot no less than 5 gallons per acre for aerial applications. 

Boll Maturity 

A boll is mature when it is too hard to be dented when squeezed between thumb and fingers, too hard to be sliced with a sharp knife, 

and when the seed coat becomes light brown in color. 

Use limitations 

Do not exceed a maximum of 2.D lb. ethephon active ingredient per acre per year through combined or repeated uses of any 

ethephon products. 

Boll Opening: Do not tank mix PREpTM brand Ethephon for Cotton and Tobacco with a desiccant if the cotton is to be spindle 

harvested. 

6 

36

COTTON 

USE EXPECTED PREP"" BRAND ONE GALLON MINIMUM SPRAY APPLICATION 

CONDITIONS ETHEPHON FOR PREpTM VOLUMES TIMING 

COnONAND BRAND (Gals/A)' 

TOBACCO ETHEPHON 

RATE FOR COTTON 

AND 

TOBACCO 

TREATS 

PintsfA LBSAJ. Acres Ground Air'''' 

PREP"'" brand Hot and dry BOaF or t tl3 1.0 6 Apply when the number of 

ETHEPHON FOR higher mature unopened bolls is 

COTTON AND Dry and 75 to aO°F 2 1.5 4 sufficient 10 produce Ih, 

TOBACCO ID 2 desired crop, See below for 

Boll Opener" Cool but above 65°F 2213 2.0 3 I"" of boll maturity. 

Treatment unilormly opens 

or bolls 710 14 days earlier. 

Rank colton 

PREP'''' brand High soil moisture 1/3 0.25 24 10 5 Apply 4 to 7 days prior to 

ETHEPHON FOR or PREpTM brand Elhephon lor 

COnONAND High lertility level Cotlon "d Tobacco boll 

TOBACCO + FOlEX@ opening application, To be· 

or used os , sequential DefolianlTank Mix'" Rank cotton treatment with, not in place 

at PREpTM brand Ethephon 

for Callan am Tobacco boll 

openinQ treatment. 

PREP'''' brand High soil moisture 1/3 0.25 24 10 3 Apply 4 to 7 days prior to 

ETHEPHON FOR or PREpTM brand Ethephon for 

COnONAND High fertility level Cotlon "d Tobacco boll 

TOBACCO + Dropp opening application. To be 

or used " , sequential DefoliantTank Mix'" 

Rank cotton treatment with, not in place 

of PREpTM brand Ethephon 

for Collon and Tobacco boll 

opening treatment. 

Pre-Conditioner for Hot, dry, above 213 0.5 12 Apply 4 to 7 days prior to 

Defoliation BO°F 1 t/3 1.0 6 ID 2 defoliant. Enhances lop 

Cool, above 65°F crop defoliation reducing 

or 

deterioration of bottom crop 

and allows for earlier 

Rank cotton harvest. 

• For best pertormance, by ground or air application, choose equipment and spray volumes that will insure unilorm coverage of foliage 

and bolls . 

•• Pretreatment With Defoliants Prior to PREpThI brand Ethephon for Cotton and Tobacco Boll Opening Treatment: If the Callan is overly 

rank or laying down in the middles and good spray coverage of the bolls with PREpTM brand Ethephon for Calion and Tobacco is 

dillicull, a pretreatment with defoliants will be useful to improve boll coverage with PREpTM brand Ethephon tor Cotton and Tobacco. 

Use dosage rates of PREpTM brand Ethephon for Callan and Tobacco recommended for boll opening. Read and observe all 

appropriate label use directions and precauflons for Ihe defoliant used . 

• ** Can use up to full label rate for each product. 

.... In California and Arizona use a volume ot no less than 5 gallons per acre for aerial applications. 

Boll Maturity 

A boll is mature when it is too hard to be dented when squeezed between thumb and fingers, too hard to be sliced with a sharp knife, 

and when the seed coat becomes light brown in color. 

Use limitations 

Do not exceed a maximum of 2.D lb. ethephon active ingredient per acre per year through combined or repeated uses of any 

ethephon products. 

Boll Opening: Do not tank mix PREpTM brand Ethephon for Cotton and Tobacco with a desiccant if the cotton is to be spindle 

harvested. 

6 
Pre-Condition for Defoliation: Do not tank mix PREpTM brand Ethephon for Cotton and Tobacco with desiccants unless plant 

desiccation is required. Do not use a defoliant before there is sufflcient mature unopened bolls to produce the desired yield (see 

General Information section on how to test for boll maturity. 

DO NOT APPLY PREpTM BRAND ETHEPHON FOR COTTON AND TOBACCO IF RAIN IS EXPECTED WITHIN 6 HOURS. 

Rainfall within 6 hours of application may reduce product performance. 

Do not plant another crop within 30 days after treatment. Small grains planted earlier than 1 month or intercropped with the collon 

crop to which PREpTM brand Ethephon for Collon and Tobacco will be applied may only be used as cover crops and may not be 

harvested for food or feed. PREpTM brand Ethephon for Cotton and Tobacco may cause yellowing and growth inhibition of treated 

small grains. 

WHEN TO HARVEST COTTON 

Do not harvest cotton sooner than 7 days after a treatment with PREpTM brand Ethephon for Collon and Tobacco. 

Observe the treated crop and harvest when optimum boll opening has been reached. Too early harvest might reduce the full advantage 

of the treatment and too late a harvest may result in reduced quality and loss of lint which will drop from the plant. 

Minimum spray 

PREpTM brand Volumes Gallonsf 

crop Situation Ethephon for Acre 

Calion and 

Tobacco 

PintsfAcre 

Directed Spray 1113 50 

Applicalion 

Over-The-Top 11/3-2213 40 

Application 

USE LIMITATIONS 

TOBACCO 

(Flue-Cured Only) 

Specific Oirections 

Use drop nozzles. Choose TG or OC spray tips designed to apply 50 • 60 

gpa al 35·40 psi and al tractor speed 01 2-3 mp~ U" 

2 nozzles per row; one on each side of the row dropped low enough to direct 

the spray to the leaves to be ripened and harvested. Thorough spray 

coverage is essential. With a directed spray, be sure to harvest all leaves 

with 20% or more yellowing. 

Treat only when leaves remaining on the stalk are mature. To ensure 

remaining leaves are mature, test spray several tobacco plants as described 

under the section "Proper Time of Treatment." Use the lower rate in a 

normally mature crop when experience indicates that minimum ripening 

indUcement Is required. Use the higher rate when the crop is heavy and has 

a tendency to be more rank or when temperatures are lower than normal. 

Always test spray to determine if the tobacco is mature enough to respond 

to treatment with PRE pHIl brand Ethephon for Collon and Tobacco. 

Apply over-the-top PREpTM brand Ethephon for Calion and Tobacco spray 

as a fine mist using three nozzles (one nozzle tip over the center of the 

plant, and one on each side) so all leaves are covered thoroughly, similar to 

the application pattem of systemic sucker control agents. Use a spray 

res sure of 40 to 60 osi. 

Do not apply PREp!M brand Ethephon for Cotton and Tobacco to immature leaves as this can result in unsatisfactory coloring, 

weight loss and reduced leaf quality. 

Do not allow the crop to over ripen in the field after using PREpTM brand Ethephon for Colton and Tobacco, since this may cause 

some reduction in yield and quality. 

Do not treat before anticipated major storm which could prevent harvest and result in crop loss. 

DO NOT APPLY PREpTM BRAND ETHEPHON FOR COTTON AND TOBACCO IF RAIN IS EXPECTED WITHIN 6 HOURS. 

Rainfall within 6 hours of application may reduce product performance. 

Do not use PREPTM brand Ethephon for Colton and Tobacco with additives other than recommended on this label. 

Do not planf another crop within 30 days after treatment. 

Do not exceed a maximum of 21bs ethephon active ingredient per acre per year through repeated uses of any ethephon products. 

7 

37

Pre-Condition for Defoliation: Do not tank mix PREpTM brand Ethephon for Cotton and Tobacco with desiccants unless plant 

desiccation is required. Do not use a defoliant before there is sufflcient mature unopened bolls to produce the desired yield (see 

General Information section on how to test for boll maturity. 

DO NOT APPLY PREpTM BRAND ETHEPHON FOR COTTON AND TOBACCO IF RAIN IS EXPECTED WITHIN 6 HOURS. 

Rainfall within 6 hours of application may reduce product performance. 

Do not plant another crop within 30 days after treatment. Small grains planted earlier than 1 month or intercropped with the collon 

crop to which PREpTM brand Ethephon for Collon and Tobacco will be applied may only be used as cover crops and may not be 

harvested for food or feed. PREpTM brand Ethephon for Cotton and Tobacco may cause yellowing and growth inhibition of treated 

small grains. 

WHEN TO HARVEST COTTON 

Do not harvest cotton sooner than 7 days after a treatment with PREpTM brand Ethephon for Collon and Tobacco. 

Observe the treated crop and harvest when optimum boll opening has been reached. Too early harvest might reduce the full advantage 

of the treatment and too late a harvest may result in reduced quality and loss of lint which will drop from the plant. 

TOBACCO 

(Flue-Cured Only) 

Minimum spray 

PREpTM brand Volumes Gallonsf 

crop Situation Ethephon for Acre Specific Oirections 

Callan and 

Tobacco 

PintsfAcre 

Directed Spray 1113 50 Use drop nozzles. Choose TG or OC spray tips designed to apply 50 • 60 

Applicalion gpa al 35·40 psi and al tractor speed 01 2-3 mp~ U" 

2 nozzles per row; one on each side of the row dropped low enough to direct 

the spray to the leaves to be ripened and harvested. Thorough spray 

coverage is essential. With a directed spray, be sure to harvest all leaves 

with 20% or more veliowinQ. 

Over-The-Top 11/3-2213 40 Treat only when leaves remaining on the stalk are mature. To ensure 

Application remaining leaves are mature, test spray several tobacco plants as described 

under the section "Proper Time of Treatment." Use the lower rate in a 

normally mature crop when experience indicates that minimum ripening 

indUcement Is required. Use the higher rate when the crop is heavy and has 

a tendency to be more rank or when temperatures are lower than normal. 

Always test spray to determine if the tobacco is mature enough to respond 

to treatment with PRE pHIl brand Ethephon for Collon and Tobacco. 

Apply over-the-top PREpTM brand Ethephon for Calion and Tobacco spray 

as a fine mist using three nozzles (one nozzle tip over the center of the 

plant, and one on each side) so all leaves are covered thoroughly, similar to 

the application pattem of systemic sucker control agents. Use a spray 

pressure of 40 to 60 psi. 

USE LIMITATIONS 

Do not apply PREp!M brand Ethephon for Cotton and Tobacco to immature leaves as this can result in unsatisfactory coloring, 

weight loss and reduced leaf quality. 

Do not allow the crop to over ripen in the field after using PREpTM brand Ethephon for Colton and Tobacco, since this may cause 

some reduction in yield and quality. 

Do not treat before anticipated major storm which could prevent harvest and result in crop loss. 

DO NOT APPLY PREpTM BRAND ETHEPHON FOR COTTON AND TOBACCO IF RAIN IS EXPECTED WITHIN 6 HOURS. 

Rainfall within 6 hours of application may reduce product performance. 

Do not use PREPTM brand Ethephon for Colton and Tobacco with additives other than recommended on this label. 

Do not planf another crop within 30 days after treatment. 

Do not exceed a maximum of 21bs ethephon active ingredient per acre per year through repeated uses of any ethephon products. 

7 
APPLICATION TIMING 

Successtul results with PREpTM brand Ethephon for Cotton and Tobacco call for treatment when leaves are mature, not overly rank 

green when sprayed. To easily detemline the proper treatment timing and the number of leaves per stalk ready for halVest, test spray 

several plants in more than one location in each lield and obselVe the response. Mature leaves will begin to yellow in 24 to 72 hours. 

Test leaves that fail to yellow in 72 hours are not mature and are not ready for PREpTM brand Ethephon for Cotton and Tobacco 

treatment. Wait a few days to pemlit turther natural maturing, then make another test spray or "maturity" check. 

To avoid quality losS and or possible leaf drop, harvest any yellowed leaves prior to application. Use lower rates under most conditions. 

Limit use of higher rates to cool (below 65Q

F at the time of treatment) slow ripening conditions. 

When you have confirmed the desired number of leaves per plant that will color, you can determine the number of acres to treat in order 

to fill the barn. 

Prepare your test spray by mixing one teaspoon of PREpTM brand Ethephon for Cotton and Tobacco in 1 quart ot water. Spray each 

test plant with about 1 oz. of this mixture, covering all leaves with a tine rnist. PREpTM brand Ethephon for Cotton and Tobacco will not 

color immature sprayed leaves. 

WHEN TO HARVEST 

All mature, sprayed leaves wiff begin to color within 24 to 72 hours after PREpTM brand Ethephon for Cotton and Tobacco application. 

The yellowing process is weather dependent; cool weather will delay, while hot, sunny weather can speed up the process. HalVest 

treated tobacco when leaves have reached the desired color intensity. 

Harvest can commence 48 hours after PREpTM brand Ethephon for Cotton and Tobacco applfcation. To detemline halVest timing and 

avoid quality loss or leaf drop, closely monitor treated crop and weather conditions. 

CURING PREP'M 8RAND ETHEPHON FOR COTTON AND TOBACCO TREATED TOBACCO 

Curing procedures are as much an art as a science and each c.ure must be judged on the basis of tobacco condition, intelVal between 

treatment and harvest, weather and type of curing facility before prescription temperature and ventilation schedules can be established. 

To obtain maximum quality, care must be taken to obselVe and control the curing process closely, especially during the late "coloring" 

and early "drying" stages ot the leaf. 

PREpTM brand Ethephon for Cotton and Tobacco treated tcbacco will have started the co!or'lng process 'Nhen halVested, reducing the 

time required in the coloring phase of curing. Treated tobacco should be dried faster. If tobacco leaves are green or contain some 

green when halVested, it may be necessary to color them for a few hours. If the leaves are completely yellow, temperature and 

ventilation must be adjusted in a manner to dry the tobacco as fast as possible without scalding. Once the leaf is dried (3/4 dry), you 

should follow normal procedures tor curing. Since PREpTM brand Ethephon for Cotlon and Tobacco treated leaves cure faster, treated 

and untreated leaves should not be cured together in the same barn. 

8 

38

APPLICATION TIMING 

Successtul results with PREpTM brand Ethephon for Cotton and Tobacco call for treatment when leaves are mature, not overly rank 

green when sprayed. To easily detemline the proper treatment timing and the number of leaves per stalk ready for halVest, test spray 

several plants in more than one location in each lield and obselVe the response. Mature leaves will begin to yellow in 24 to 72 hours. 

Test leaves that fail to yellow in 72 hours are not mature and are not ready for PREpTM brand Ethephon for Cotton and Tobacco 

treatment. Wait a few days to pemlit turther natural maturing, then make another test spray or "maturity" check. 

To avoid quality losS and or possible leaf drop, harvest any yellowed leaves prior to application. Use lower rates under most conditions. 

Limit use of higher rates to cool (below 65Q

F at the time of treatment) slow ripening conditions. 

When you have confirmed the desired number of leaves per plant that will color, you can determine the number of acres to treat in order 

to fill the barn. 

Prepare your test spray by mixing one teaspoon of PREpTM brand Ethephon for Cotton and Tobacco in 1 quart ot water. Spray each 

test plant with about 1 oz. of this mixture, covering all leaves with a tine rnist. PREpTM brand Ethephon for Cotton and Tobacco will not 

color immature sprayed leaves. 

WHEN TO HARVEST 

All mature, sprayed leaves wiff begin to color within 24 to 72 hours after PREpTM brand Ethephon for Cotton and Tobacco application. 

The yellowing process is weather dependent; cool weather will delay, while hot, sunny weather can speed up the process. HalVest 

treated tobacco when leaves have reached the desired color intensity. 

Harvest can commence 48 hours after PREpTM brand Ethephon for Cotton and Tobacco applfcation. To detemline halVest timing and 

avoid quality loss or leaf drop, closely monitor treated crop and weather conditions. 

CURING PREP'M 8RAND ETHEPHON FOR COTTON AND TOBACCO TREATED TOBACCO 

Curing procedures are as much an art as a science and each c.ure must be judged on the basis of tobacco condition, intelVal between 

treatment and harvest, weather and type of curing facility before prescription temperature and ventilation schedules can be established. 

To obtain maximum quality, care must be taken to obselVe and control the curing process closely, especially during the late "coloring" 

and early "drying" stages ot the leaf. 

PREpTM brand Ethephon for Cotton and Tobacco treated tcbacco will have started the co!or'lng process 'Nhen halVested, reducing the 

time required in the coloring phase of curing. Treated tobacco should be dried faster. If tobacco leaves are green or contain some 

green when halVested, it may be necessary to color them for a few hours. If the leaves are completely yellow, temperature and 

ventilation must be adjusted in a manner to dry the tobacco as fast as possible without scalding. Once the leaf is dried (3/4 dry), you 

should follow normal procedures tor curing. Since PREpTM brand Ethephon for Cotlon and Tobacco treated leaves cure faster, treated 

and untreated leaves should not be cured together in the same barn. 

8 
) 

IMPORTANT: READ BEFORE USE 

Read the entire Directions for Use, Conditions, Disclaimer of Warranties and Limitations of Liability before using this product. If terms 

are not acceptable, return the unopened product container at once. 

By using this product, user or buyer accepts the following Conditions, Disclaimer of Warranties and Limitations of Liability. 

CONDITIONS: The directions for use of this product are believed to be adequate and must be followed carefully. However, it is 

impossible to eliminate all risks associated with the use of this product. Crop iniury, ineffectiveness or other unintended consequences 

may result because of such factors as weather conditions, presence of other materials, or the manner of use or application, all of which 

are beyond the control of Bayer CropScience. All such risks shall be assumed by the user or buyer. 

DISCLAIMER OF WARRANTIES: TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, BAYER CROPSCIENCE MAKES NO 

OTHER WARRANTIES, EXPRESS OR IMPLIED, OF MERCHANTABILITY OR OF FITNESS FOR A PARTICULAR PURPOSE OR 

OTHERWISE, THAT EXTEND BEYOND THE STATEMENTS MADE ON THIS LABEL. No agent of Bayer CropScience is authorized to 

make any warranties beyond those contained herein or to modify the warranties contained herein. TO THE EXTENT CONSISTENT 

WITH APPLICABLE LAW, BAYER CROPSCIENCE DISCLAIMS ANY LIABILITY WHATSOEVER FOR SPECIAL, INCIDENTAL OR 

CONSEQUENTIAL DAMAGES RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT. 

L1MtTATIONS OF LIABILITY: TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, THE EXCLUSIVE REMEDY OF THE 

USER OR BUYER FOR ANY AND ALL LOSSES, INJURIES OR DAMAGES RESULTING FROM THE USE OR HANDLING OF THIS 

PRODUCT, WHETHER IN CONTRACT, WARRANTY, TORT, NEGUGENCE, STRICT LIABILITY DR OTHERWISE, SI-Wl. NOT EXCEED THE 

PURCHASE PRICE PAID, DRAT BAYERCROPSCIENCE'S BECTION, THE REPLACEMENT OF PROOJCT. 

NET CONTENTS: 2.5 GALLONS 

Dropp, Ginstar, Def and Guthion are registered trademarks and Prep and Ultra are trademarks of Bayer. 

Folex is a registered trademark of Amvac Chemical Corporation. 

Harvade is a registered trademark of Uniroyal Company. 

Malathion is a trademark of American Cyanamid Company. 

4 Bayer Crop Science 

Bayer CropScience lP 

P,O. Box 12014, 2 T.W. Alexander Drive 

Research Triangle Park, North carolina 27109 

1·866·99SAYER (1·866·992·293n 

PREpTM brand Ethephon for Collon and Tobacco (MASTER) 11/09/2010 

9 

39

) 

IMPORTANT: READ BEFORE USE 

Read the entire Directions for Use, Conditions, Disclaimer of Warranties and Limitations of Liability before using this product. If terms 

are not acceptable, return the unopened product container at once. 

By using this product, user or buyer accepts the following Conditions, Disclaimer of Warranties and Limitations of Liability. 

CONDITIONS: The directions for use of this product are believed to be adequate and must be followed carefully. However, it is 

impossible to eliminate all risks associated with the use of this product. Crop iniury, ineffectiveness or other unintended consequences 

may result because of such factors as weather conditions, presence of other materials, or the manner of use or application, all of which 

are beyond the control of Bayer CropScience. All such risks shall be assumed by the user or buyer. 

DISCLAIMER OF WARRANTIES: TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, BAYER CROPSCIENCE MAKES NO 

OTHER WARRANTIES, EXPRESS OR IMPLIED, OF MERCHANTABILITY OR OF FITNESS FOR A PARTICULAR PURPOSE OR 

OTHERWISE, THAT EXTEND BEYOND THE STATEMENTS MADE ON THIS LABEL. No agent of Bayer CropScience is authorized to 

make any warranties beyond those contained herein or to modify the warranties contained herein. TO THE EXTENT CONSISTENT 

WITH APPLICABLE LAW, BAYER CROPSCIENCE DISCLAIMS ANY LIABILITY WHATSOEVER FOR SPECIAL, INCIDENTAL OR 

CONSEQUENTIAL DAMAGES RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT. 

L1MtTATIONS OF LIABILITY: TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, THE EXCLUSIVE REMEDY OF THE 

USER OR BUYER FOR ANY AND ALL LOSSES, INJURIES OR DAMAGES RESULTING FROM THE USE OR HANDLING OF THIS 

PRODUCT, WHETHER IN CONTRACT, WARRANTY, TORT, NEGUGENCE, STRICT LIABILITY DR OTHERWISE, SI-Wl. NOT EXCEED THE 

PURCHASE PRICE PAID, DRAT BAYERCROPSCIENCE'S BECTION, THE REPLACEMENT OF PROOJCT. 

NET CONTENTS: 2.5 GALLONS 

Dropp, Ginstar, Def and Guthion are registered trademarks and Prep and Ultra are trademarks of Bayer. 

Folex is a registered trademark of Amvac Chemical Corporation. 

Harvade is a registered trademark of Uniroyal Company. 

Malathion is a trademark of American Cyanamid Company. 

4 Bayer Crop Science 

Bayer CropScience lP 

P,O. Box 12014, 2 T.W. Alexander Drive 

Research Triangle Park, North carolina 27109 

1·866·99SAYER (1·866·992·293n 

PREpTM brand Ethephon for Collon and Tobacco (MASTER) 11/09/2010 

9 
Material to be added to an e-Jacket/Jacket 

Reg. No. '-.bLj-lfl ~ 

Description: fV..u.//~6~/.n ffLS 

1. ft Placement within the e-Jacket/jacket: 

o Default: (chronological, top = newest) 

o File Location: (PDF page number, i.e., "before page 

45") 

2. 0 Send to Data Extraction contractors this material: 

X Newly stamped accepted label 

o Notification 

o NewCSF 

o Other: 

3. Attach this coversheet to the top of the material or jacket. It 

must be well organized and clipped together, NOT STAPLED. 

Then give the material with this coversheet to staff in the 

Information Services Center (Room S-4900). 

Reviewer's Name: Tot'Y7 k.r t"?/ 

Phone: ,:,og' ,}lftr3 Division: ~ b 

Date: JL/;~h Created August 19, 2008 

40

Material to be added to an e-Jacket/Jacket 

Reg. No. '-.bLj-lfl ~ 

Description: fV..u.//~6~/.n ffLS 

1. ft Placement within the e-Jacket/jacket: 

o Default: (chronological, top = newest) 

o File Location: (PDF page number, Le., "before page 

45") 

2. 0 Send to Data Extraction contractors this material: 

X Newly stamped accepted label 

o Notification 

o NewCSF 

o Other: 

3. Attach this coversheet to the top of the material or jacket. It 

must be well organized and clipped together, NOT STAPLED. 

Then give the material with this coversheet to staff in the 

Information Services Center (Room S-4900). 

Reviewer's Name: Tot'Y7 k.r t"?/ 

Phone: ,:,og' ,}lftr3 Division: ~ b 

Date: JL/;~h Created August 19, 2008 
UNITED STATES ENVIRONMENTAL PROTECTION AGENCY 

WASHINGTON, D.C. 20460 

Laura Phelps 

Regulatory Affairs 

Bayer CropScience 

2 T. W. Alexander Drive 

Raleigh, NC 27709 

RE; Amendment Dated May 20, 2010 

Decision 441883 

PREP brand Ethephon for Cotton and Tobacco 

EPA Reg. Number 264w418 

Dear Ms. Phelps: 

OFFICE OF CHE~IICAL SAFETY 

,HiD POLLUTION PREVENTIO;\' 

The amendment referred to above, submitted in connection with registration under the Federal Insecticide, Fungicide, 

and Rodenticide Act (FIFRA), as amended, to provide a label which revises the storage and disposal section to exactly 

match the Bayer companywwide template approved by EPA November 19. 2009, is acceptable. 

Submit two copies ofa final printed label and attach a copy of this letter with it. Enclosed please find a copy of the 

revised label stamped "Accepted". If you have questions concerning this letter, please me at 703w308-9443. 

Sincerely, 

rJ=fPyJf.~ Tony Kish 

Product Manager, Team 22 

Fungicide Branch 

Registration Division (7504P) 

41

UNITED STATES ENVIRONMENTAL PROTECTION AGENCY 

WASHINGTON, D.C. 20460 

Laura Phelps 

Regulatory Affairs 

Bayer CropScience 

2 T. W. Alexander Drive 

Raleigh, NC 27709 

RE; Amendment Dated May 20, 2010 

Decision 441883 

PREP brand Ethephon for Cotton and Tobacco 

EPA Reg. Number 264w418 

Dear Ms. Phelps: 

OFFICE OF CHE~IICAL SAFETY 

,HiD POLLUTION PREVENTIO;\' 

The amendment referred to above, submitted in connection with registration under the Federal Insecticide, Fungicide, 

and Rodenticide Act (FIFRA), as amended, to provide a label which revises the storage and disposal section to exactly 

match the Bayer companywwide template approved by EPA November 19. 2009, is acceptable. 

Submit two copies ofa final printed label and attach a copy of this letter with it. Enclosed please find a copy of the 

revised label stamped "Accepted". If you have questions concerning this letter, please me at 703w308-9443. 

Sincerely, 

rj=o,n.vJ 

Tony Kish 

Product Manager, Team 22 

Fungicide Branch 

Registration Division (7504P) 
PRE P TM brand Ethephon FOR COTTON AND TOBACCO 

For Commercial Use Or Agricultural Use Only. Not For Residential Use 

ACTIVE INGREmENT: Ethephon (2-Chloroethyl) phosphonic acid~ ............................................. , ...................... , •.... 55.4% 

INERT INGREDIENTS: ............... , ..•...•...•... ,,,.,, .......................................... ., ............................................................... ,. 44.6GIa 

KEEP OUT OF REACH OF CHILDREN 

DANGER PELIGRO 

Si usted no entiende' la etiqueta, busque a alguien para que se la explique 

(If you do not understand the label, find someone to explain it to you' 

For MEDfCAlAnd TRANSPORTATION Emergencies ONLY catl24 Hours A Day 1-800·334·7577 

ForPRODUCT USE Information Can 1·86S-99BAVER (1-8SS·992·2937) 

The use of this product for a variety of plant growth regulation uses are protected by United States and foreign patents inclUding 

U.S. Palent 4,240,819. No license is granted to use Ihis product in counllies other than the United States or fur any use not 

contemplated by this label. liabilitY for patent infringement may result from use or sale of this product oUl$ide the United States. 

FIRST AID 

IFIN EVES: • Hold eye open and rinse slowly and gently with waler fur 15-20 minutes. 

• Remove contact lenses, jf present, after the first 5 minutes, then continue rinsing eye. 

• Call1!P9ison control center or doctor for treatment advice. 

IF ON SKIN OR • Take off contaminated dolhing. 

CLOTHING: • Rinse skin immediately with plenty of water fur 15-20 minutes. 

• Call a Doison control center or doctor for treatment advice. 

IF SWALLOWED: • Immediately call a poison control center or doctor for treatment advice. 

• Do not induce vomiting unless told to do so by a poison alntrol center or doctor. 

• Have person sip a glass of water if able to swallOw. 

• Do not ~ive anv!hing bv mouth -to an unconscious person. 

ForMEDICAl Emergencies Call 24 Hours A Day 1-800-334-7577. 

Have the oroduct cootainer or label with YOU when caUina a Doison conlIOl center or doctor or aaine for treatment 

NOTE TO PHYSICIAN: Treat symptomatically. Consideration should be given to the posSibility that overexposure to materials other 

than this product may have occurred. No specific antidote is available. Probable mucosal damage may contraindicate the use of 

. gastric lavace 

PRECAUTIONARY STATEMENTS 

DANGER 

HAZARDS TO HUMANS AND DOMESTIC ANIMALS 

CORROSIVE. Causes irreversible eye damage and skin bums. Harmful if swallowed or absorbed through skin. Do not get in eyes, on 

skin or on clothing, 

PERSONAL PROTECTIVE EQUIPMENT (PPE) 

Applicators and other handlers must wear coveralls over short-sleeved shirts and short pants, chemical resistant gtoves made of any 

waterproof material (such as Nitrile, Butyl, Neoprene and/or Barrier Laminate), chemical-resistant footwear plus socks, prolective 

eyewear, chemical-resistant headgear fur overhead exposure and chemicaJ..reslstani apron when cleaning equipment or mixing and 

Wading. 

Discard clothing and other absorbent male rials that have been drenched or heavily contaminated with this products concentrate. Do not 

reuse them. Follow manufacturer's instructions for cleaning/maintaining PPE. If no such instructions for washables, use detergent and 

hot water. Keep and wash PPE separately from other laundry. 1 

42

PRE P TM brand Ethephon FOR COTTON AND TOBACCO 

For Commercial Use Or Agricultural Use Only. Not For Residential Use 

ACTIVE INGREmENT: Ethephon (2-Chloroethyl) phosphonic acid~ ............................................. , ...................... , •.... 55.4% 

INERT INGREDIENTS: ............... , ..•...•...•... ,,,.,, .......................................... ., ............................................................... ,. 44.6GIa 

KEEP OUT OF REACH OF CHILDREN 

DANGER PELIGRO 

Si usted no entiende'la etiqueta, busque a alguien para que se la explique ,"sled, 

(If you do not understand the label, find someone to explain it to 

ForPRODUCT USE Information Can 1·86S-99BAVER (1-866·992·2937) 

NOV 09 20m 

The use of this product for a variety of plant growth regulation uses are protected by United States and foreign patents inclUding 

U.S. Palent 4,240,819. No license is granted to use Ihis product in counllies other than the United States or for any use not 

contemplated by this label. liabilitY for patent infringement may result from use or sale of this product oUl$ide the United States. 

FIRST AID 

IFIN EVES: • Hold eye open and rinse slowly and gently with waler for 15-20 minutes. 

• Remove contact lenses, jf present, after the first 5 minutes, then continue rinsing eye. 

• Call a poison control center or doctor for treatment advice. 

IF ON SKIN OR • Take off contaminated dolhing. 

CLOTHING: • Rinse skin immediately with plenty of water for 15-20 minutes. 

• Call a poison control center or doctor for treatment advice. 

IF SWALLOWED: • Immediately call a poison control center or doctor for treatment advice. 

• Do not induce vomiting unless told to do so by a poison alntrol center or doctor. 

• Have person sip a glass of water if able to swallOw. 

• Do not aive anvlhirm....Qymouth -to an unconscious person. 

ForMEDICAl Emergencies Call 24 Hours A Day 1-800-334-7577. 

Have the product cootainer or label with YOU when caUinq a Doison conlIOl center or doctor or qainQ for treatment 

NOTE TO PHYSICIAN: Treat symptomatically. Consideration should be given to the posSibility that overexposure to materials other 

than this product may have occurred. No specifiC antidote is available. Probable mucosal damage may contraindicate the use of 

, oastric lava~e 

PRECAUTIONARY STATEMENTS 

DANGER 

HAZARDS TO HUMANS AND DOMESTIC ANIMALS 

CORROSIVE. Causes irreversible eye damage and skin bums. Harmful if swallowed or absorbed through skin. Do not get in eyes, on 

skin or on clothing, 

PERSONAL PROTECTIVE EQUIPMENT (PPE) 

Applicators and other handlers must wear coveralls over short-sleeved shirts and short pants, chemical resistant gtoves made of any 

waterproof material (such as Nitrile, Butyl, Neoprene and/or Barrier Laminate), chemical-resistant footwear plus socks, prolective 

eyewear, chemical-resistant headgear for overhead exposure and chemicaJ..reslstani apron when cleaning equipment or mixing and 

Wading. 

Discard clothing and other absorbent male rials that have been drenched or heavily contaminated with this products concentrate. Do not 

reuse them. Follow manufacturer's instructions for cleaning/maintaining PPE. If no such instructions for washables, use detergent and 

hot water. Keep and wash PPE separately from other laundry. 1 
VVhen handlers use closed systems, enclosed cabs, or aircraft in a manner that meets the requirements listed in the Worker Protection 

Standard (WPS) for agricultural pesticides [40 CFR 170.240 (d) (4-6»), the handler PPE requirements may be reduced or modified as 

speCified in the WPS. 

User Safety Recommendations 

Users should wash hands before ealing, drinking, chewing gum, using tobacco or using the toilet 

Users should remove clothing immediately if pesticide gets inside, Then wash body thoroughly and put on clean clothing. 

Users should remove PPE immediately after handling this product, As soon as possible, wash thoroughly and change into clean 

clothing. Wash the outside of gloves before removing. 

ENWRONMENTALHAZARDS 

Do not apply d"lrectly to water, or to areas where surface water is present-or to intertidal areas below the mean high water mark. 

Do not contaminate water when disposing of equipment washwaters. 

Do not contaminate water used for irrigation or domestic p.Jrposes. 

SPRAY DRIFT 

Avoid spray drift Do not appJy when weather conditions may cause drift. Do not arrow this product t-o drift on to non-target areas. Drift 

may result in illegal residues or Injury to adjacent crops and vegetation, in the form of leaf yellowing and defolialion. To avoid spray 

drift, DO NOT apply aerially when v.ind speed is greater than 10 mph or during periods of temperature inversions. Use of larger droplet 

size wiR also reduce spray drift. 

AVOIDING SPRAY DRIFT AT THE APPLICATION SITE tS THE RESPONSIBILITY OF THE APPLICATOR, 

The interaction of many equipment-ancJ...weather...related factors determine the'potential for spray drift. The appUcalor is responsible for 

considering aJf these factors when making deCisions. 

The following drift management requirements must be followed to avoid Off-target movement from aerial applications to agricultural field 

crops. These requirements do not apply to forestry applications, public health uses or to applications using dry formulations. 

1. The distance -of the outer most nozzles on the boom must not exceed 3/4 the length of the wingspan or rotor. 

2. Nozzles must always point backward parallel with the air stream and never be pointed downwards more than 45 degrees. 

VVhere stales have more stringent regulations, they should be observed. 

The appHcator should be familiar with and take into account the information covered in the Aerial Drift Reduction Advisory betow: 

AERIAL DRIFT REDUCTION ADVISORY 

[This section is advisory in nature and does not supersede the mandatory label requirements]. 

INfORMATION ON DROPlET SIZE 

The most effective way to reduce drift potential is to apply large droplets. The best drift management strategy is to apply the largest 

droplets that provide sufficient coverage and control. Applying larger droplets reduces drift potential, but will not prevent drift if 

applications are made improperly, or under unfavorable environmental conditions (See Wind, Temperature and HumK::lity, and 

Temperature Inversions). 

CONTROlliNG DROPlET SIZE 

Volume w Use high flow rate nOZZles to apply the highest practical spray Volume. Nozzles..vith higher rated flows produce larger 

droplets. 

Pressure - Do not exceed the nozzle manufacturer's recommended pressures. For many nozzle types lower pressure produces larger 

droplets. When hig,erflow rates are needed, use higher flow rale noules instead of increaSing pressure. 

Number of nozzles w Use the minimum number of nozzles that provide uniform coverage. 

Nozzle Orientation w Orienting nozzles so that the spray is released parallel to the airstream produces larger droplets than other 

orientations and is the recommended practice. Significant deflection from horizontal will reduce droplet size and increase drift potential. 

Nozzle Type - Use a nozzle type that is designed for the intended application. VVith most nozzle types, narrower spray angles produce 

larger droplets. Consider using low-drift nozzles. Solid stream nozzles oriented straight back produce the largest droplets and the 

lowest drift. 

BOOM lENGTH 

For some use patterns, reducing the effective boom tength to less than 3/4 of the wingspan or rotor length may further reduce drift 

without redUCing swath width. 

APPUCATION HEtGHT 

Applications shoutd not be made at a height greater than 10 feet above the top of the target plants unless a greater height is required 

for aircraft safety. Making applications at the lowest height that is safe reduces exposure of droplets to evaporation and wind. 

2 

43

VVhen handlers use closed systems, enclosed cabs, or aircraft in a manner that meets the requirements listed in the Worker Protection 

Standard (WPS) for agricultural pesticides [40 CFR 170.240 (d) (4-6»), the handler PPE requirements may be reduced or modified as 

speCified in the WPS. 

User Safety Recommendations 

Users should wash hands before ealing, drinking, chewing gum, using tobacco or using the toilet 

Users should remove clothing immediately if pesticide gets inside, Then wash body thoroughly and put on clean clothing. 

Users should remove PPE immediately after handling this product, As soon as possible, wash thoroughly and change into clean 

clothing. Wash the outside of gloves before removing. 

ENWRONMENTALHAZARDS 

Do not apply d"lrectly to water, or to areas where surface water is present-or to intertidal areas below the mean high water mark. 

Do not contaminate water when disposing of equipment washwaters. 

Do not contaminate water used for irrigation or domestic p.Jrposes. 

SPRAY DRIFT 

Avoid spray drift Do not appJy when weather conditions may cause drift. Do not arrow this product t-o drift on to non-target areas. Drift 

may result in illegal residues or Injury to adjacent crops and vegetation, in the form of leaf yellowing and defolialion. To avoid spray 

drift, DO NOT apply aerially when v.ind speed is greater than 10 mph or during periods of temperature inversions. Use of larger droplet 

size wiR also reduce spray drift. 

AVOIDING SPRAY DRIFT AT THE APPLICATION SITE tS THE RESPONSIBILITY OF THE APPLICATOR, 

The interaction of many equipment-ancJ...weather...related factors determine the'potential for spray drift. The appUcalor is responsible for 

considering aJf these factors when making deCisions. 

The following drift management requirements must be followed to avoid Off-target movement from aerial applications to agricultural field 

crops. These requirements do not apply to forestry applications, public health uses or to applications using dry formulations. 

1. The distance -of the outer most nozzles on the boom must not exceed 3/4 the length of the wingspan or rotor. 

2. Nozzles must always point backward parallel with the air stream and never be pointed downwards more than 45 degrees. 

VVhere stales have more stringent regulations, they should be observed. 

The appHcator should be familiar with and take into account the information covered in the Aerial Drift Reduction Advisory betow: 

AERIAL DRIFT REDUCTION ADVISORY 

[This section is advisory in nature and does not supersede the mandatory label requirements]. 

INfORMATION ON DROPlET SIZE 

The most effective way to reduce drift potential is to apply large droplets. The best drift management strategy is to apply the largest 

droplets that provide sufficient coverage and control. Applying larger droplets reduces drift potential, but will not prevent drift if 

applications are made improperly, or under unfavorable environmental conditions (See Wind, Temperature and HumK::lity, and 

Temperature Inversions). 

CONTROlliNG DROPlET SIZE 

Volume w Use high flow rate nOZZles to apply the highest practical spray Volume. Nozzles..vith higher rated flows produce larger 

droplets. 

Pressure - Do not exceed the nozzle manufacturer's recommended pressures. For many nozzle types lower pressure produces larger 

droplets. When hig,erflow rates are needed, use higher flow rale noules instead of increaSing pressure. 

Number of nozzles w Use the minimum number of nozzles that provide uniform coverage. 

Nozzle Orientation w Orienting nozzles so that the spray is released parallel to the airstream produces larger droplets than other 

orientations and is the recommended practice. Significant deflection from horizontal will reduce droplet size and increase drift potential. 

Nozzle Type - Use a nozzle type that is designed for the intended application. VVith most nozzle types, narrower spray angles produce 

larger droplets. Consider using low-drift nozzles. Solid stream nozzles oriented straight back produce the largest droplets and the 

lowest drift. 

BOOM lENGTH 

For some use patterns, reducing the effective boom tength to less than 3/4 of the wingspan or rotor length may further reduce drift 

without redUCing swath width. 

APPUCATION HEtGHT 

Applications shoutd not be made at a height greater than 10 feet above the top of the target plants unless a greater height is required 

for aircraft safety. Making applications at the lowest height that is safe reduces exposure of droplets to evaporation and wind. 

2 
SWAm ADJUSTMENT 

When applications are made with a crosswind, the swath will be displaced downwind. Therefore, on the up and downwind edges of the 

field, the applicator should compensate for this displacement by adjusting the path of the aircraft upwind. Swath adjustment distance 

should increase, With increasing dr"lft potential (higher >Mnd, smaller drops, etc.). 

WIND 

Drift potential is lowest between wind speeds of 2 ~ 10 mph. However, many factors, including droplet size and equipment type 

determine drift potential al any given speed. Application should be aVoided belOw 2 mph due to variable wind direction and high 

inversion potential. NOTE: local terrain can influence wind patterns. EvelY applJcator should be familiar with local wind patterns and 

how they affect sjXay drift. 

TEMPERATURE AND HUMIDITY 

When making applications in low relative hum·d.lty, set up equipment to produce larger droplets to compensale for evaporation. Droplet 

evaporallon is most severe when condilions are both hot and dry. 

TEMPERATURE INVERSIONS 

Applications should not occur during a temperature inversion because drift potential is high. Temperature inversions reslrict vertical air 

mIXing, which causes smail suspended droplets to remain in a concentrated cloud. This cloud can move in unpredictable directions due 

to Ihe light variable winds common during inversions, Temperature Inversions are characterized by increasing temperatures wilh 

altitude and are common on nights with limited cloud cover and light to no wind. They begin to form as the sun sets and often continue 

inlo the morning. Their presence can be indicated by ground fog; however, if fog is not present, Inversions can also be identified by the 

movement of smoke from a ground source or an a'ircraft smoke generator. Smoke Ihat Jayers and moves laterally in a concentraled 

cloud (under low wind conditions) indicates an inversion, while smoke that moves upward and rapIdly dissipates indicates good vertical 

air mixing. 

SENSmVE AREAS 

The pestidde should only be appfied when the potential for drift to adjacent sensitive areas (e.g. residential areas, bodies of water, 

known habitat for threatened or endangered spec'Ie5, non-targel crops) is minimal (e.g. when wind is blowing away from the sensitive 

areas). 

USE PRECAUTIONS 

Do not apply PREpTM brand Ethephon for Cotton and Tobacco through any type of irrigation system. 

Avoid spray drift to nearby crops as this product will cause modifications in plant growth. Plant injury or reduced yields will result. 

Mix only the amount of spray you expect to use each day. Do not aUow mixed solution to stand overnight. 

DIRECTIONS FOR USE 

It is a violation of Federal law to use !his product in a manner inconsistent With its labeling. 

Do not apply th'ls product in a way Ihat will contact workers or other persons, ·eilher direclly or through dlift. Only protected handlers 

may be in the area during appncation. For any requirements specific to your State or Tribe, consult the agency responsible for pesticide 

regulations. Read entire label before using this product. 

AGRICULTURAL USE REQUIREMENTS 

Use this product only in accordance with its labeling and ~ the Worl<er Protection Standard, 4D CFR part 170. This standard contains 

requirements for the protection of agricultural workers on farms, forests, nurseries, and greenhouses, and handlers of agricultural 

pesticIdes. It contains requirements for training, decontamination, notification, and emergency assistance. It also contains specific 

instructions and exceptions pertaining to the statements on this Jabel aboul personal protective equipment (PPE), notification to workers 

and restrlcled-entfy intervals. The requirements in this box only applY to uses of this product that are covered by the Worker Protection 

Standard. 

Do not enter or aUow worker entry into treated areas during the restricted-entry interval (REt) of 48 hours. The REI is 72 hours in areas 

where average rainfall is less than 2S inches per year. 

pPE required for early entfy to treated areas that Is permitted under the Worl<er ProtectiOn Standard and that invol\les contact with 

anything that has been Ireated such as plants, soil or water is coveratts over long~sleeved shirt and long pants, chemIcal resislant 

gloves made of any waterproof material, such as nitrile, butyl, neoprene, or barlier laminate, chemical resislant footwear plus socks, and 

protective eyewear. For overhead exposure, chemical-resistant headgear is also required. 

Notify workers ofthe application by warning them orally and posting warning signs at entrances to treated areas. 

3 

44

SWAm ADJUSTMENT 

When applications are made with a crosswind, the swath will be displaced downwind. Therefore, on the up and downwind edges of the 

field, the applicator should compensate for this displacement by adjusting the path of the aircraft upwind. Swath adjustment distance 

should increase, With increasing dr"lft potential (higher >Mnd, smaller drops, etc.). 

WIND 

Drift potential is lowest between wind speeds of 2 ~ 10 mph. However, many factors, including droplet size and equipment type 

determine drift potential al any given speed. Application should be aVoided belOw 2 mph due to variable wind direction and high 

inversion potential. NOTE: local terrain can influence wind patterns. EvelY applJcator should be familiar with local wind patterns and 

how they affect sjXay drift. 

TEMPERATURE AND HUMIDITY 

When making applications in low relative hum·d.lty, set up equipment to produce larger droplets to compensale for evaporation. Droplet 

evaporallon is most severe when condilions are both hot and dry. 

TEMPERATURE INVERSIONS 

Applications should not occur during a temperature inversion because drift potential is high. Temperature inversions reslrict vertical air 

mIXing, which causes smail suspended droplets to remain in a concentrated cloud. This cloud can move in unpredictable directions due 

to Ihe light variable winds common during inversions, Temperature Inversions are characterized by increasing temperatures wilh 

altitude and are common on nights with limited cloud cover and light to no wind. They begin to form as the sun sets and often continue 

inlo the morning. Their presence can be indicated by ground fog; however, if fog is not present, Inversions can also be identified by the 

movement of smoke from a ground source or an a'ircraft smoke generator. Smoke Ihat Jayers and moves laterally in a concentraled 

cloud (under low wind conditions) indicates an inversion, while smoke that moves upward and rapIdly dissipates indicates good vertical 

air mixing. 

SENSmVE AREAS 

The pestidde should only be appfied when the potential for drift to adjacent sensitive areas (e.g. residential areas, bodies of water, 

known habitat for threatened or endangered spec'Ie5, non-targel crops) is minimal (e.g. when wind is blowing away from the sensitive 

areas). 

USE PRECAUTIONS 

Do not apply PREpTM brand Ethephon for Cotton and Tobacco through any type of irrigation system. 

Avoid spray drift to nearby crops as this product will cause modifications in plant growth. Plant injury or reduced yields will result. 

Mix only the amount of spray you expect to use each day. Do not aUow mixed solution to stand overnight. 

DIRECTIONS FOR USE 

It is a violation of Federal law to use !his product in a manner inconsistent With its labeling. 

Do not apply th'ls product in a way Ihat will contact workers or other persons, ·eilher direclly or through dlift. Only protected handlers 

may be in the area during appncation. For any requirements specific to your State or Tribe, consult the agency responsible for pesticide 

regulations. Read entire label before using this product. 

AGRICULTURAL USE REQUIREMENTS 

Use this product only in accordance with its labeling and ~ the Worl<er Protection Standard, 4D CFR part 170. This standard contains 

requirements for the protection of agricultural workers on farms, forests, nurseries, and greenhouses, and handlers of agricultural 

pesticIdes. It contains requirements for training, decontamination, notification, and emergency assistance. It also contains specific 

instructions and exceptions pertaining to the statements on this Jabel aboul personal protective equipment (PPE), notification to workers 

and restrlcled-entfy intervals. The requirements in this box only applY to uses of this product that are covered by the Worker Protection 

Standard. 

Do not enter or aUow worker entry into treated areas during the restricted-entry interval (REt) of 48 hours. The REI is 72 hours in areas 

where average rainfall is less than 2S inches per year. 

pPE required for early entfy to treated areas that Is permitted under the Worl<er ProtectiOn Standard and that invol\les contact with 

anything that has been Ireated such as plants, soil or water is coveratts over long~sleeved shirt and long pants, chemIcal resislant 

gloves made of any waterproof material, such as nitrile, butyl, neoprene, or barlier laminate, chemical resislant footwear plus socks, and 

protective eyewear. For overhead exposure, chemical-resistant headgear is also required. 

Notify workers ofthe application by warning them orally and posting warning signs at entrances to treated areas. 

3 
STORAGE AND DISPOSAL 

Do not contaminate water, food, or feed by storage or d'isposai. 

PESTICIDE STORAGE 

Store in a cool, dry place and away from food, feed and other pesticides. IF SPILLED: If container is broken or contents have spilled, 

fcnow alf precautions indicated above and clean up immediately, Before cleaning up, put on fuillengih trousers, long sleeved shirt, 

prole clive gloves, and goggles or face shield. Soak up spill with absorbent media such as sand, earth or other suitable malerial and 

dispose of waste al an approved waste disposal facility. 

PESTICIOE DISPOSAL 

Pesticide wastes are acutely hazardous. Improper disposal of excess pesticide, spray mixlure, or rinsate is a violation of Federal law. If 

these wastes cannot be disposed of by use according to label instructions, contact your State Pesticide or Environmental Control 

Agency or the Hazardous Wasle representative at the nearest EPA Regional Office for guidance. 

CONTAINER DISPOSAL 

Rtgld, Non-refillable containers small enough to shake (i,e" with capacities equatto or less than 5 gallons) 

Non-refillable container. Do not reuse or refill this container. Triple rinse or pressure rinse container (or equivalent) promptly after 

emptying. Triple rinse as follow-;: Empty the remaining contents into application equipment or a mix tank and drain for to seconds after 

the flow begins to drip. Fill the container t/4 full with water and recap. Shake for 10 seconds. Pour rinsate inlo application equipment or 

a mix tank or slore rinsate for later use ord·lsposal. Drain for 10 seconds after the flow begins 10 drip. Repeat this procedure two more 

times. Once container is rinsed, offer for recycling if avaifable or puncture and dispose of in a sanitary landfill. 

Rtgld Non-refillable containers that are too large to shako. (I.e., with capacllles greater than 5 gallons or 50 Ibs) 

Non-refllfable Containers 

Non-refillable containers - Do not reuse or refill this container. Refer to Boltom Discharge IBC or Top Discharge IBC. Drums. Kegs 

information as follows. 

BoHom DIscharge IBC (&.g. -Schuetz Cagod IBC or Snyder Square Stackable) 

Pressure rinsing the container before final disposal Is the responsibility of the person disposing of the container. To pressure rinse the 

container before final disposal. empty the remaining contents from the IBC into application equipment or mix tank. Raise the bottom of 

the tBC by 1.5 inches on the side which is opposite of the bottom discharge valve to promote more complele product removal. 

Completely remove the top fid of the IBC. Use water pressurized to at least 40 PSI to rinse all interior portions. Continuously pump or 

drain rinsate into application equipment or rinsale collection system While pressure rinsing. Continue pressure rinsing for 2 minutes or 

until rinsale becomes clear. Replace the lid and close bottom valve. 

Top Discharge IBC, Drums, Kegs (e.g.-Snyder 120 Next Gen, Bonar 8120, Drums, Kegs). 

Triple rinsirg the container before final disposal Is the responsibility of the person disposing of the container. To triple rinse the 

container before final disposal. empty the remaining contents from this container into application aquipment or mix tank. Fill the 

container al least 10 percent full with water. Agitate vigorously or recirculat& water with the pump for 2 minutes. Rinse all Interior 

surfaces. Pour or pump rinsale into application equipment or rinsate coRection system. Repeat this procedure two more times. Once 

container is rinsed, offer for recyclIng if available or puncture and dispose of in a sanitary landlill. 

Refillabte Containers 

Refillable conlalner - Refer to Bottom Discharge IBC or Top Discharge IBC, Drums, Kegs information as folioM. Refill this contaIner 

with pesticide only. Do not reuse this container for any other purpose. Arter emptying product from container, either retum container to 

Bayer CropScience per instructions from Bayer CropScience Customer Service Center (1-800.5274781) or rinse and either recycfe or 

dispose of the container as follows: 

Bottom Discharge IBC (e.g. - Schuetz Caged IBC or Snyder Square Stackabte) 

Pressure rinsing the container before final disposal is the responsib~ity of the person disposing of the container. Cleaning before refiRing 

Is the responsibiftty of the refiller. To pressure rinse the container before final disposal, empty the remaining contents from the IBC into 

application equipment or mix tank. Raise the bottom of the IBC by 1.5 inches on the side which is opposite of the bottom discharge 

valve to promote more complete product removal. Completafy remove the top lid of the IBC. Use water pressurized to at least 40 PSI to 

rinse all interior portions. Continuously pump or drain rinsate Into appUcation equipment or rinsate collection system while pressure 

rinsing. Continue pressure rinsing for 2 minutes or until rinsate becomes clear. Repface the lid and close boltom valve. 

Top DIscharge IBC, Drums, Kegs (o.g.- Snydor 120 Next Gon, Bonar B120, Drums, Kegs). 

Triple rinsing the container before final disposal is the responsibility of the person disposing of the container. Cleaning before refilling 'IS 

the responsibility of the refiller. To triple rinse the containers before final disposal, empty the remaining contents from this container into 

application equipment or mix lank. Fill the container at leest to percent full with water. Agitate vigorously or recirculate water with the 

pump for 2 minutes. Rinse all Interior surfaces. Pour or pump rinsate into appfication eqUipment or rinsale collection system. Repeat this 

procedure two more times. Once container is rinsed, offer for recycling if avaifable or puncture and dispose of in a sanitary landfifl. 

4 

45

STORAGE AND DISPOSAL 

Do not contaminate water, food, or feed by storage or d'isposai. 

PESTICIDE STORAGE 

Store in a cool, dry place and away from food, feed and other pesticides. IF SPILLED: If container is broken or contents have spilled, 

fcnow alf precautions indicated above and clean up immediately, Before cleaning up, put on fuillengih trousers, long sleeved shirt, 

prole clive gloves, and goggles or face shield. Soak up spill with absorbent media such as sand, earth or other suitable malerial and 

dispose of waste al an approved waste disposal facility. 

PESTICIOE DISPOSAL 

Pesticide wastes are acutely hazardous. Improper disposal of excess pesticide, spray mixlure, or rinsate is a violation of Federal law. If 

these wastes cannot be disposed of by use according to label instructions, contact your State Pesticide or Environmental Control 

Agency or the Hazardous Wasle representative at the nearest EPA Regional Office for guidance. 

CONTAINER DISPOSAL 

Rtgld, Non-refillable containers small enough to shake (i,e" with capacities equatto or less than 5 gallons) 

Non-refillable container. Do not reuse or refill this container. Triple rinse or pressure rinse container (or equivalent) promptly after 

emptying. Triple rinse as follow-;: Empty the remaining contents into application equipment or a mix tank and drain for to seconds after 

the flow begins to drip. Fill the container t/4 full with water and recap. Shake for 10 seconds. Pour rinsate inlo application equipment or 

a mix tank or slore rinsate for later use ord·lsposal. Drain for 10 seconds after the flow begins 10 drip. Repeat this procedure two more 

times. Once container is rinsed, offer for recycling if avaifable or puncture and dispose of in a sanitary landfill. 

Rtgld Non-refillable containers that are too large to shako. (I.e., with capacllles greater than 5 gallons or 50 Ibs) 

Non-refllfable Containers 

Non-refillable containers - Do not reuse or refill this container. Refer to Boltom Discharge IBC or Top Discharge IBC. Drums. Kegs 

information as follows. 

BoHom DIscharge IBC (&.g. -Schuetz Cagod IBC or Snyder Square Stackable) 

Pressure rinsing the container before final disposal Is the responsibility of the person disposing of the container. To pressure rinse the 

container before final disposal. empty the remaining contents from the IBC into application equipment or mix tank. Raise the bottom of 

the tBC by 1.5 inches on the side which is opposite of the bottom discharge valve to promote more complele product removal. 

Completely remove the top fid of the IBC. Use water pressurized to at least 40 PSI to rinse all interior portions. Continuously pump or 

drain rinsate into application equipment or rinsale collection system While pressure rinsing. Continue pressure rinsing for 2 minutes or 

until rinsale becomes clear. Replace the lid and close bottom valve. 

Top Discharge IBC, Drums, Kegs (e.g.-Snyder 120 Next Gen, Bonar 8120, Drums, Kegs). 

Triple rinsirg the container before final disposal Is the responsibility of the person disposing of the container. To triple rinse the 

container before final disposal. empty the remaining contents from this container into application aquipment or mix tank. Fill the 

container al least 10 percent full with water. Agitate vigorously or recirculat& water with the pump for 2 minutes. Rinse all Interior 

surfaces. Pour or pump rinsale into application equipment or rinsate coRection system. Repeat this procedure two more times. Once 

container is rinsed, offer for recyclIng if available or puncture and dispose of in a sanitary landlill. 

Refillabte Containers 

Refillable conlalner - Refer to Bottom Discharge IBC or Top Discharge IBC, Drums, Kegs information as folioM. Refill this contaIner 

with pesticide only. Do not reuse this container for any other purpose. Arter emptying product from container, either retum container to 

Bayer CropScience per instructions from Bayer CropScience Customer Service Center (1-800.5274781) or rinse and either recycfe or 

dispose of the container as follows: 

Bottom Discharge IBC (e.g. - Schuetz Caged IBC or Snyder Square Stackabte) 

Pressure rinsing the container before final disposal is the responsib~ity of the person disposing of the container. Cleaning before refiRing 

Is the responsibiftty of the refiller. To pressure rinse the container before final disposal, empty the remaining contents from the IBC into 

application equipment or mix tank. Raise the bottom of the IBC by 1.5 inches on the side which is opposite of the bottom discharge 

valve to promote more complete product removal. Completafy remove the top lid of the IBC. Use water pressurized to at least 40 PSI to 

rinse all interior portions. Continuously pump or drain rinsate Into appUcation equipment or rinsate collection system while pressure 

rinsing. Continue pressure rinsing for 2 minutes or until rinsate becomes clear. Repface the lid and close boltom valve. 

Top DIscharge IBC, Drums, Kegs (o.g.- Snydor 120 Next Gon, Bonar B120, Drums, Kegs). 

Triple rinsing the container before final disposal is the responsibility of the person disposing of the container. Cleaning before refilling 'IS 

the responsibility of the refiller. To triple rinse the containers before final disposal, empty the remaining contents from this container into 

application equipment or mix lank. Fill the container at leest to percent full with water. Agitate vigorously or recirculate water with the 

pump for 2 minutes. Rinse all Interior surfaces. Pour or pump rinsate into appfication eqUipment or rinsale collection system. Repeat this 

procedure two more times. Once container is rinsed, offer for recycling if avaifable or puncture and dispose of in a sanitary landfifl. 

4 
Refillabte Contatners 

End users are authorized to remove tamper evident cables as required to remove the product from the container unless the container is 

equipped with one way valves and refilling or returning is planned. If this is the case, end users are not authorized to remove tamper 

evident cables, one way valves or clean co"ntainer. See Container Disposal instructions under Storage and Disposal. 

GENERAL INFORMATION 

conON 

A foliar spray of PREpThi brand Ethe~on for cotton and Tobacco will accelerate opaning of mature unopened cotton bolls and enhance 

defoliation Which can resu~ in earlier harvest with an increased recoverable yield. PREp1M brand Ethephon for Cotton and Tobacoo 

treatment on cotton allows increased efficiency from a once-over harvest. 

TOBACCO (FLUE-CURED): A folfar spray of PREp1M brand 8hephon for Cotton and Tobacco promotes early. un·lform "yellowing" of 

mature tobacco. PREp1M brand Ethephon for Cotton and Tobacco reduces curing time, allowing more efficient use of curing barn 

space, and increased control over harvest schedules. 

SPRAY PREPARATION 

Add U2 to 3/4 of the required amount of water to the spray tank. Start agitation. Add the required amount of PREpTM brand Ethephon 

for Cotton and Tobacco, and the remaining amount of water. Prepare only as much spray solution as can be used on the day of mixing. 

Do not allow spray solution to stand overnight Do not spill the concentrated product on spray equipment. or any airplane parts. 

ANY SPILLS SHOULD BE RINSED IMMEDIATELY WITH PLENTY OF WATER. 

Use of a nurse tank is highly recommended for avoiding possible spills of concentrated formulation on spray equipment or any airplane 

parts. 

TANK MIXTURES WITH DEFOLIANTS AND iNSECnCIDES 

PREplI.I brand Ethephon for Cotton and Tobacco is compatible with DEFiIl, FOLEX®, Drop~. Dropp® Unra m, Ginstar®, Harvade®. 

Methyl Parathion, Guthion®, and Malathionm. PREpm brand Ethephon for Cotton and Tobacco may be applied in sequence or as a 

tank mixture (DO NOT TANK MIX VVlTH DESICCANTS IF COTTON IS TO BE SPtNDLE HARVESTED). Follow all applicable use 

precautions and rate per acre recommendations on labels of products applied as tank mixtures or In sequence with PREP 1M brand 

Elhephon for Cotton and Tobacco. In some cases slight reduction in boll opening response has been observed when tank mixes wilh 

defoliants were used. 

Good agitation in the spray tank is essential and a tank mixture should not be allowed to stand without agitation for more than 5 to 10 

minutes. Read and observe all appropriate label use directions and precautions for the defoliants and insecticides used. 

NOTE: UNDER CERTAIN CONDITiONS, TANK MtXTURES OF PREp1101 BRAND ETI-lEPHON FOR COTTON AND TOBACCO WITH 

DESICCANTS CONTAINING SODIUM CHLORATE COULD RESULT IN THE FORMATION OF HYPOCHLOROUS ACIDS WHICH 

ON HEATING VVlLL EMIT TOXIC CHLORlPE FUMES. 

DO NOT MIX PREpm BRAND ETHEPHON FOR COTTON AND TOBACCO WITH AMMONIUM THIOSULFATE. SUCH TANK 

MIXTURES MAY RESULT IN FORMATION OF TOXIC FUMES. 

EQUIPMENT CLEANING 

Because of Ihe acidic nature of this product, prolonged exposure to spray deposit will damage acryNc plastics, certain paints, and 

metals. 

Rinse thoroughly with a detergent and water all exposed acrylic plastic-type materials (e.g., aircraft windshields). and painted surfaces 

within an hour after exposure to spray depOsits. 

At the end of each day, rinse thoroughly with a detergent and water all the metal parts of the aircraft and the associated spray 

equipment exposad to the spray depOSits. 

5 

46

Refillabte Contatners 

End users are authorized to remove tamper evident cables as required to remove the product from the container unless the container is 

equipped with one way valves and refilling or returning is planned. If this is the case, end users are not authorized to remove tamper 

evident cables, one way valves or clean co"ntainer. See Container Disposal instructions under Storage and Disposal. 

GENERAL INFORMATION 

conON 

A foliar spray of PREpThi brand Ethe~on for cotton and Tobacco will accelerate opaning of mature unopened cotton bolls and enhance 

defoliation Which can resu~ in earlier harvest with an increased recoverable yield. PREp1M brand Ethephon for Cotton and Tobacoo 

treatment on cotton allows increased efficiency from a once-over harvest. 

TOBACCO (FLUE-CURED): A folfar spray of PREp1M brand 8hephon for Cotton and Tobacco promotes early. un·lform "yellowing" of 

mature tobacco. PREp1M brand Ethephon for Cotton and Tobacco reduces curing time, allowing more efficient use of curing barn 

space, and increased control over harvest schedules. 

SPRAY PREPARATION 

Add U2 to 3/4 of the required amount of water to the spray tank. Start agitation. Add the required amount of PREpTM brand Ethephon 

for Cotton and Tobacco, and the remaining amount of water. Prepare only as much spray solution as can be used on the day of mixing. 

Do not allow spray solution to stand overnight Do not spill the concentrated product on spray equipment. or any airplane parts. 

ANY SPILLS SHOULD BE RINSED IMMEDIATELY WITH PLENTY OF WATER. 

Use of a nurse tank is highly recommended for avoiding possible spills of concentrated formulation on spray equipment or any airplane 

parts. 

TANK MIXTURES WITH DEFOLIANTS AND iNSECnCIDES 

PREplI.I brand Ethephon for Cotton and Tobacco is compatible with DEFiIl, FOLEX®, Drop~. Dropp® Unra m, Ginstar®, Harvade®. 

Methyl Parathion, Guthion®, and Malathionm. PREpm brand Ethephon for Cotton and Tobacco may be applied in sequence or as a 

tank mixture (DO NOT TANK MIX VVlTH DESICCANTS IF COTTON IS TO BE SPtNDLE HARVESTED). Follow all applicable use 

precautions and rate per acre recommendations on labels of products applied as tank mixtures or In sequence with PREP 1M brand 

Elhephon for Cotton and Tobacco. In some cases slight reduction in boll opening response has been observed when tank mixes wilh 

defoliants were used. 

Good agitation in the spray tank is essential and a tank mixture should not be allowed to stand without agitation for more than 5 to 10 

minutes. Read and observe all appropriate label use directions and precautions for the defoliants and insecticides used. 

NOTE: UNDER CERTAIN CONDITiONS, TANK MtXTURES OF PREp1101 BRAND ETI-lEPHON FOR COTTON AND TOBACCO WITH 

DESICCANTS CONTAINING SODIUM CHLORATE COULD RESULT IN THE FORMATION OF HYPOCHLOROUS ACIDS WHICH 

ON HEATING VVlLL EMIT TOXIC CHLORlPE FUMES. 

DO NOT MIX PREpm BRAND ETHEPHON FOR COTTON AND TOBACCO WITH AMMONIUM THIOSULFATE. SUCH TANK 

MIXTURES MAY RESULT IN FORMATION OF TOXIC FUMES. 

EQUIPMENT CLEANING 

Because of Ihe acidic nature of this product, prolonged exposure to spray deposit will damage acryNc plastics, certain paints, and 

metals. 

Rinse thoroughly with a detergent and water all exposed acrylic plastic-type materials (e.g., aircraft windshields). and painted surfaces 

within an hour after exposure to spray depOsits. 

At the end of each day, rinse thoroughly with a detergent and water all the metal parts of the aircraft and the associated spray 

equipment exposad to the spray depOSits. 

5 
COTTON 

USE EXPECTED PREplM BRANQ ONE GALLON MINIMUM SPRAY APPlICAnON 

CONOmONS ETHEPHON FOR PREP'" VOLUMES TIMING 

COTTON ANa BRAND (Gats/A)" 

TOBACCO ETHEPHON 

RATE FOR COTTON 

AND 

TOBACCO 

TREATS 

PintslA lBSAJ. Acres Ground Air"" 

PREP""brnnd Hot and dry 80"F or 1 113 1.0 6 Apply when the number of 

ETHEPHON FOR higher mature unopened bolls is 

COTIONAND Dry and 75 to BO"F 2 1.5 4 sufficient' ~ produce ~, 

TOBACCO 10 2 desired crop. See below for 

Bol/Opener" Cool but above 65°F 2 213 2.0 3 test of boll maturity. 

Treatment unifonnly opens 

0' bolls 7 to 14 days earlier. 

Rank cotton 

PREP'''' brand High soil moisture 113 0.25 24 10 5 Apply 4 to 7 days prior to 

ETHEPHON FOR " PREpTM brand Ethephon for 

COnONANO High fertiHty level Cotton aod Tobacco boll 

TOBACCO + fOlEX""' opening applicalion. To be 

" used as a sequential Defoliant Tank Mix'" Rank cotton treatment wHh, not in place 

of PREp'IM brand Ethephon 

for Cotton and Tobacco bon 

opening treatment. 

PREP"" brand High soil moisture 113 0.25 24 10 3 Apply 4 to 7 days prior to 

ETHEPHON FOR " PREpl'Id brand Ethephon for 

COTTON AND High fertility level Cotton aod Tobacco boll 

TOBACCO + Oropp opening application. To be 

" used as a sequential Defoliant Tank Mix"· Rank cotton treatment with, not in place 

of PREpTM brand Ethephon 

for Cotton and Tobacco boll 

ooeninQ treatment. 

Pre-Conditioner '" Hot, dry, above 213 0.5 12 Apply 4 to 7 days prior to 

Oefoliation BOoF 1 113 1.0 6 10 2 deforl<!ml Enhances top 

Cool, above 65~F crop defonation redUcing 

0' 

deterioralion of bottom crop 

aod allows 10, earlier 

Rank cotton harvest. 

• For best peliormance, by ground or air application, choose equipment and spray volumes that win insure uniform coverage of foliage 

and bans . 

•• Pretreatment With Defoliants Prior to PREplM brand Elhephon for Cotton and Tobacco Boll Opening Treatment: If the cotton is overly 

rank or laying down in fhe mlddlos and good spray coverage of the bolls with PREpm brand Ethephon for Cotton and Tobacco is 

difficult, a pretreatment with defoHants will be useful to improve boll coverage wilh PREplM brand Ethephon for Cotton and 1obao::o. 

Use dosage rates of PREpTM brand Ethephon for Cotton and Tobacco recommended for boll opening. Read and observe all 

appropriate label use direction!; and precautions for the defoliant used. 

*". Can use up to full label rate for each product . 

...... In California and Arizona use a volume of no less than 5 gallons per acre for aeriat applications. 

Boll Maturity 

A borr is mature when it is too hard to be dented when squeezed bet.v.oeen thumb and fingers, too hard to be sliced with a sharp knife, 

and when the seed coat becomes light brown in color. 

Use limitations 

Do nol exceed a maximum of 2.0 Ib, ethephon active ingredient per acre per year through combined or repeated uses 01 any 

etheJ110n products. 

Boll Opening: Do not tank mix PREpTM brand Ethephon for Cotton and Tobacco with a desiccant if the rotton is to be spindle 

harvested. 

6 

47

COTTON 

USE EXPECTED PREplM BRANQ ONE GALLON MINIMUM SPRAY APPlICAnON 

CONOmONS ETHEPHON FOR PREP'" VOLUMES TIMING 

COTTON ANa BRAND (Gats/A)" 

TOBACCO ETHEPHON 

RATE FOR COTTON 

AND 

TOBACCO 

TREATS 

PintslA lBSAJ. Acres Ground Air"" 

PREP""brnnd Hot and dry 80"F or 1 113 1.0 6 Apply when the number of 

ETHEPHON FOR higher mature unopened bolls is 

COTIONAND Dry and 75 to BO"F 2 1.5 4 sufficient' ~ produce ~, 

TOBACCO 10 2 desired crop. See below for 

Bol/Opener" Cool but above 65°F 2 213 2.0 3 test of boll maturity. 

Treatment unifonnly opens 

0' bolls 7 to 14 days earlier. 

Rank cotton 

PREP'''' brand High soil moisture 113 0.25 24 10 5 Apply 4 to 7 days prior to 

ETHEPHON FOR " PREpTM brand Ethephon for 

COnONANO High fertiHty level Cotton aod Tobacco boll 

TOBACCO + fOlEX""' opening applicalion. To be 

" used as a sequential Defoliant Tank Mix'" Rank cotton treatment wHh, not in place 

of PREp'IM brand Ethephon 

for Cotton and Tobacco bon 

opening treatment. 

PREP"" brand High soil moisture 113 0.25 24 10 3 Apply 4 to 7 days prior to 

ETHEPHON FOR " PREpl'Id brand Ethephon for 

COTTON AND High fertility level Cotton aod Tobacco boll 

TOBACCO + Oropp opening application. To be 

" used as a sequential Defoliant Tank Mix"· Rank cotton treatment with, not in place 

of PREpTM brand Ethephon 

for Cotton and Tobacco boll 

ooeninQ treatment. 

Pre-Conditioner '" Hot, dry, above 213 0.5 12 Apply 4 to 7 days prior to 

Oefoliation BOoF 1 113 1.0 6 10 2 deforl<!ml Enhances top 

Cool, above 65~F crop defonation redUcing 

0' 

deterioralion of bottom crop 

aod allows 10, earlier 

Rank cotton harvest. 

• For best peliormance, by ground or air application, choose equipment and spray volumes that win insure uniform coverage of foliage 

and bans . 

•• Pretreatment With Defoliants Prior to PREplM brand Elhephon for Cotton and Tobacco Boll Opening Treatment: If the cotton is overly 

rank or laying down in fhe mlddlos and good spray coverage of the bolls with PREpm brand Ethephon for Cotton and Tobacco is 

difficult, a pretreatment with defoHants will be useful to improve boll coverage wilh PREplM brand Ethephon for Cotton and 1obao::o. 

Use dosage rates of PREpTM brand Ethephon for Cotton and Tobacco recommended for boll opening. Read and observe all 

appropriate label use direction!; and precautions for the defoliant used. 

*". Can use up to full label rate for each product . 

...... In California and Arizona use a volume of no less than 5 gallons per acre for aeriat applications. 

Boll Maturity 

A borr is mature when it is too hard to be dented when squeezed bet.v.oeen thumb and fingers, too hard to be sliced with a sharp knife, 

and when the seed coat becomes light brown in color. 

Use limitations 

Do nol exceed a maximum of 2.0 Ib, ethephon active ingredient per acre per year through combined or repeated uses 01 any 

etheJ110n products. 

Boll Opening: Do not tank mix PREpTM brand Ethephon for Cotton and Tobacco with a desiccant if the rotton is to be spindle 

harvested. 

6 
Pre·Condition for Defoliation: Do not lank mix PREpTM brand Ethephon for Colton and Tobacco With desiccanls unless plant 

desiccation is required. Do not use a defoliant before there is sufficient malure unopened bolls 10 produce Ihe desired yield (see 

General Information section on how to test for boll maturity. 

DO NOT APPLY PREpTM BRAND ETHEPHON FOR COTTON AND TOBACCO IF RAIN IS EXPECTED WITHIN 6 HOURS. 

Rainfall ;vjlhin 6 hours of applicalion may reduce product performance. 

00 not plant anolher crop within 30 days after treatment. Small graIns planted earlier than 1 month or intercropped with the cotton 

crop 10 which PREpTM brand Elhephon for Cotlon and Tobacco will be sppUed may only be used as cover crops and may nol be 

harvesled for food or feed. PREplM brand Ethephon for Cotton and Tobacco may cause yeno....;ng and growth inhibition of treated 

small graIns. 

WHEN TO HARVEST COTTON 

Do not harvest cotton sooner than 7 days after a treatment with PREPTM brand Ethephon for Cotlon and Tobacco. 

Observe the trealed crop and harvest when oplimum bon opening has been reached. Too early harvest might reduce the rull advantage 

of the trealment and too lale a harvest may result in reduced quality and loss of lint which will drop from the plant. 

TOBACCO 

(Flue-Cured Only) 

PREP"'" brand 

Minimum Spray 

Volumes Gallonsl 

Crop Situation Eth!phon for Acre Specific orrections 

Cotton and 

Tobacco 

Pints/Acre 

Directed Spray t 1/3 50 Use drop nozzles. Choose TG or OC spray tips designed to apply 50 ~ 60 

Application gpa " 3S-40 psi ,"d at tractor speed of 2-3 mph. U,. 

2 nozzles per row; one on each side of the row dropped low enough to direc! 

the spray to Ihe leaves. to be ripened and harvested. Thorough spray 

coverage is essential. With a direcled spray, be sure to harvest all leaves 

with 20% or more vellowina. 

Over~The-Top t 113-22/3 40 Treat only when leaves remaining on the stalk are mature. To ensure 

Application remaining leaves are mature, test spray several tobacco planls as described 

under Ihe section "Proper Time of Treatment" Use the lower rate in a 

normally mature crop when experience indicates that minimum ripening 

inducement is required. Use the higher rale when the crop Is heavy and has 

a tendency to be more rank or when temperalures are lower than normal. 

Always test spray 10 determine if the tobacco is malure enough to respond to 

treatment with PREpm brand Ethephon for Cotton and Tobacco. 

Apply over~the-top PREpm brand Ethephon for Cotton and Tobacco spray 

as a line mist using Ihree nozzles (one nozzle tip over the center of the 

plant, and one on each side) so all leaves are covered thoroughly, similar to 

the application pattern of syslemic sucker conlrol agenls. 

I pressure of 40 to 60 osi. 

Use a spray 

USEUf,1rrATIONS 

~ Do not apply PREP'IM brand Ethephon for Cation and Tobacco to immalure leaves as this can result in unsatisfactory coloring, 

weight loss and reduced teaf quanty. 

Do not allow the crop to over ripen in Ihe field after using PREpru brand Ethephon for Cotton and Tobacco, since this may cause 

some reduclion in yield and qUality, 

00 not ireat before anticipated major slorm which could prevent harvest and result in crop loss. 

DO NOT APPLY PREpm BRAND ETHEPHON FOR COTTON AND TOBACCO IF RAIN IS EXPECTED WITHIN 6 HOURS, 

RaInfall within 6 hours of application may reduce product perfOrmance. 

Do not Use PREpm brand Ethephon for Cotton and Tobacco wilh additives other than recommended on Ihis label. 

Do not plant another crop wilhin 30 days after treatment. 

Do not exceed a maximum of2 Ibs elhephon active ingredient per acre per year through repeated uses of any ethephon products. 

7 

48

Pre·Condition for Defoliation: Do not lank mix PREpTM brand Ethephon for Colton and Tobacco With desiccanls unless plant 

desiccation is required. Do not use a defoliant before there is sufficient malure unopened bolls 10 produce Ihe desired yield (see 

General Information section on how to test for boll maturity. 

DO NOT APPLY PREpTM BRAND ETHEPHON FOR COTTON AND TOBACCO IF RAIN IS EXPECTED WITHIN 6 HOURS. 

Rainfall ;vjlhin 6 hours of applicalion may reduce product performance. 

00 not plant anolher crop within 30 days after treatment. Small graIns planted earlier than 1 month or intercropped with the cotton 

crop 10 which PREpTM brand Elhephon for Cotlon and Tobacco will be sppUed may only be used as cover crops and may nol be 

harvesled for food or feed. PREplM brand Ethephon for Cotton and Tobacco may cause yeno....;ng and growth inhibition of treated 

small graIns. 

WHEN TO HARVEST COTTON 

Do not harvest cotton sooner than 7 days after a treatment with PREPTM brand Ethephon for Cotlon and Tobacco. 

Observe the trealed crop and harvest when oplimum bon opening has been reached. Too early harvest might reduce the rull advantage 

of the trealment and too lale a harvest may result in reduced quality and loss of lint which will drop from the plant. 

PREP"'" brand 

Minimum Spray 

Volumes Gallonsl 

Crop Situation Eth!phon for Acre 

Cotton and 

Tobacco 

Pints/Acre 

Directed Spray t 1/3 50 

Application 

Over~The-Top t 113-22/3 40 

Application 

USEUf,1rrATIONS 

TOBACCO 

(Flue-Cured Only) 

Specific orrections 

Use drop nozzles. Choose TG or OC spray tips designed to apply 50 ~ 60 

gpa " 3S-40 psi ,"d at tractor speed of 2-3 mph. U,. 

2 nozzles per row; one on each side of the row dropped low enough to direc! 

the spray to Ihe leaves. to be ripened and harvested. Thorough spray 

coverage is essential. With a direcled spray, be sure to harvest all leaves 

with 20% or more yellowing. 

Treat only when leaves remaining on the stalk are mature. To ensure 

remaining leaves are mature, test spray several tobacco planls as described 

under Ihe section "Proper Time of Treatment" Use the lower rate in a 

normally mature crop when experience indicates that minimum ripening 

inducement is required. Use the higher rale when the crop Is heavy and has 

a tendency to be more rank or when temperalures are lower than normal. 

Always test spray 10 determine if the tobacco is malure enough to respond to 

treatment with PREpm brand Ethephon for Cotton and Tobacco. 

Apply over~the-top PREpm brand Ethephon for Cotton and Tobacco spray 

as a line mist using Ihree nozzles (one nozzle tip over the center of the 

plant, and one on each side) so all leaves are covered thoroughly, similar to 

the application pattern of syslemic sucker conlrol agenls. I pressure of 40 to 60 psi. Use a spray 

~ Do not apply PREP'IM brand Ethephon for Cation and Tobacco to immalure leaves as this can result in unsatisfactory coloring, 

weight loss and reduced teaf quanty. 

Do not allow the crop to over ripen in Ihe field after using PREpru brand Ethephon for Cotton and Tobacco, since this may cause 

some reduclion in yield and qUality, 

00 not ireat before anticipated major slorm which could prevent harvest and result in crop loss. 

DO NOT APPLY PREpm BRAND ETHEPHON FOR COTTON AND TOBACCO IF RAIN IS EXPECTED WITHIN 6 HOURS, 

RaInfall within 6 hours of application may reduce product perfOrmance. 

Do not Use PREpm brand Ethephon for Cotton and Tobacco wilh additives other than recommended on Ihis label. 

Do not plant another crop wilhin 30 days after treatment. 

Do not exceed a maximum of2 Ibs elhephon active ingredient per acre per year through repeated uses of any ethephon products. 

7 
APPLICATION TIMING 

Successful results with PREpTI.! brand Ethephon for Cotton and Tobacco call for treatment when leaves are mature, not overly rank 

green when sprayed. To easYy determine the proper treatment tim'lng and the number of leaves per stalk ready for harvest, test spray 

several plants in more than one locatIon in each field and observe the response. Mature leaves will begin to yellow in 24 to 72 hours. 

Test leaves that fail to yellow in 72 hours are not mature and are not ready for PREpno brand Ethephon for Cotton and Tobacco 

treatment. Wait a few days to pennit further natural maturing, then make another test spray or~maturily" check. 

To avoid quaHty loss and or pOSSible leaf drop, harvest any yenowed leaves prior to application, Use lower rates under most conditions. 

Umit use of higher rates to cool (below 65~F at the time of treatment) slow ripening conditions. 

When you have confirmed the desired number of leaves per plant that will color, you can determine the number of acres to treat in order 

to fill the barn. 

Prepare your test spray by mixing one teaspoon of PREPTM brand Ethephon for Cotton and Tobacco in 1 quart of water. Spray each 

test plant v.ith about 1 oz. of this mixture, covering all leaves with a fine mist. PREprn brand Ethephon for Cotton and Tobacco will not 

color immature sprayed leaves. 

WHEN TO HARVEST 

All mature, sprayed leaves win begin to color within 24 to 72 hours after PREpTM brand Ethephon for Cotton and Tobacco application. 

The yellowing process is weather dependent, cool weather will delay, While hot, sunny weather can speed up the process. Harvest 

treated tobacco when leaves have reached the desired color intenSity. 

Harvest can commence 48 hours after PREpm brand Ethephon for Cotton and Tobacco application. To determine harvest timing and 

avoid quaffty loss or leaf drop, closely monitor treated crop and weather conditions. 

CURING PREp .... BRAND ETHfPHON FOR COTTON AND TOBACCO TREATED TOBACCO 

CUring procedures are as much an art as a sdence and each cure must be judged on the basis of tobacco condition, intervat between 

treatment and harvest, weather and type of curing facility before prescription temperature and ventilation schedules can be estabr,shed. 

To obtain maximum quality, care must be taken to observe and control the curing process closely, especially during the late "colOring" 

and early ~drying" siages of the leaf. 

PREpm brand Ethephon for Cotton and Tobacco treated tobacco win have started the coloring process when harvested, reducing thCil 

time required in the cotoring phase of curing. Traated tobacco shoutd be dried faster. If tobacco teaves are green or contain some 

green when harvested, it may be necessary to color them for a few hours, If the leaves are completely yerrow, temperature and 

ventilation must be adjusted in a manner to dry the tobacco as fast as possible without scalding. Once the leaf is dried (3/4 dry), you 

should follow normal prOcedures for curing. Since PREpm brand Ethephon for Cotton and Tobacco treated leaves cure faster, treated 

and untreated leaves should not be cured together in the same bam. 

• 

49

APPLICATION TIMING 

Successful results with PREpTI.! brand Ethephon for Cotton and Tobacco call for treatment when leaves are mature, not overly rank 

green when sprayed. To easYy determine the proper treatment tim'lng and the number of leaves per stalk ready for harvest, test spray 

several plants in more than one locatIon in each field and observe the response. Mature leaves will begin to yellow in 24 to 72 hours. 

Test leaves that fail to yellow in 72 hours are not mature and are not ready for PREpno brand Ethephon for Cotton and Tobacco 

treatment. Wait a few days to pennit further natural maturing, then make another test spray or~maturily" check. 

To avoid quaHty loss and or pOSSible leaf drop, harvest any yenowed leaves prior to application, Use lower rates under most conditions. 

Umit use of higher rates to cool (below 65~F at the time of treatment) slow ripening conditions. 

When you have confirmed the desired number of leaves per plant that will color, you can determine the number of acres to treat in order 

to fill the barn. 

Prepare your test spray by mixing one teaspoon of PREPTM brand Ethephon for Cotton and Tobacco in 1 quart of water. Spray each 

test plant v.ith about 1 oz. of this mixture, covering all leaves with a fine mist. PREprn brand Ethephon for Cotton and Tobacco will not 

color immature sprayed leaves. 

WHEN TO HARVEST 

All mature, sprayed leaves win begin to color within 24 to 72 hours after PREpTM brand Ethephon for Cotton and Tobacco application. 

The yellowing process is weather dependent, cool weather will delay, While hot, sunny weather can speed up the process. Harvest 

treated tobacco when leaves have reached the desired color intenSity. 

Harvest can commence 48 hours after PREpm brand Ethephon for Cotton and Tobacco application. To determine harvest timing and 

avoid quaffty loss or leaf drop, closely monitor treated crop and weather conditions. 

CURING PREp .... BRAND ETHfPHON FOR COTTON AND TOBACCO TREATED TOBACCO 

CUring procedures are as much an art as a sdence and each cure must be judged on the basis of tobacco condition, intervat between 

treatment and harvest, weather and type of curing facility before prescription temperature and ventilation schedules can be estabr,shed. 

To obtain maximum quality, care must be taken to observe and control the curing process closely, especially during the late "colOring" 

and early ~drying" siages of the leaf. 

PREpm brand Ethephon for Cotton and Tobacco treated tobacco win have started the coloring process when harvested, reducing thCil 

time required in the cotoring phase of curing. Traated tobacco shoutd be dried faster. If tobacco teaves are green or contain some 

green when harvested, it may be necessary to color them for a few hours, If the leaves are completely yerrow, temperature and 

ventilation must be adjusted in a manner to dry the tobacco as fast as possible without scalding. Once the leaf is dried (3/4 dry), you 

should follow normal prOcedures for curing. Since PREpm brand Ethephon for Cotton and Tobacco treated leaves cure faster, treated 

and untreated leaves should not be cured together in the same bam. 

• 
IMPORTANT: READ BEFORE USE 

Read the entire Directions for Use, Condilfons, Disclaimer of Warranties and Limitations of Liability before using this product. If terms 

are not acceptable, return the unopened product container al once. 

By using this product, user or buyer accepts the following Concf'ltions, Disclaimer of Warranties and limitations of l.iability. 

CONDITIONS: The directions for use of this product are believed to be adequate and must be followed carefully. However, it is 

impossible to eliminale atl risks associated with the use of this product. Crop injury, ineffectiveness or other unintended consequences 

may result because of such factors as weather conditions, presence of other materials, or the manner of use or application, all of which 

are beyond the control of Bayer CropScience. All such risks shat! be assumed by the user or buyer. 

DISCLAIMER OF WARRANTIES; TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, BAYER CROP SCIENCE MAKES NO 

OTHER WARRANTIES, EXPRESS OR IMPLIED, OF MERCHANTABILITY OR OF FITNESS FOR A PARTICULAR PURPOSE OR 

OTHERVVlSE, THAT EXTEND BEYOND THE STATEMENTS MADE ON THIS LABEL. No agent of Bayer CropScienoo Is authorized 10 

make any warranfles beyond Ihose conlained herein or 10 modify Ihe warranlies conlained herein. TO THE EXTENT CONSISTENT 

WITH APPLICABLE LAW, BAYER CROPSCIENCE DISCLAIMS ANY LIABILITY WHATSOEVER FOR SPECIAL, INCIDENTAL OR 

CONSEQUENTIAL DAMAGES RESULTING FROM THE USE OR HANDliNG OF THIS PRODUCT. 

LIMITATIONS OF UABILlTY: TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, THE EXCLUSIVE REMEDY OF THE 

USER OR BUYER FOR ANY AND ALL LOSSES, INJURIES OR DAMAGES RESULTING FROM THE USE OR HANDLING OF THIS 

PRODUCT, WHETHER IN C~T, ~, TORT, NEGUGENCE, STRICT UABllITY OR OTHERWSE, SHALl. NOT EXCEED THE 

PURCH4.SE PRICE PAID. DRAT M YER CROPSCIENCE'S 8.ECTION, THE REPlACEMENT OF PRODUCT. 

NET CONTENTS: 2.5 GALLONS 

Dropp, Ginslar, Def and Gulhion are regislered Irademarks and Prep and Ultra are trademarks of Bayer. 

Folex is a registered Irademark of Amvac Chemical Corporalion. 

Harvade is a regislered trademark of Uniroyal Company. 

Malalhion is a Irademark of American Cyanamid Company. 

Bayer CropScience lP 

P.O. Box 12014, 2 T.W. Alexander Drive 

Research Triangle Park. North Carolina 27709 

1·866-99BAVER (1-866-992-2937) 

PREpTM brand Elhephon for Cotton and Tobacco (PENDING) 05/24110, Resubmitted 06/01/10 

9 

50

IMPORTANT: READ BEFORE USE 

Read the entire Directions for Use, Condilfons, Disclaimer of Warranties and Limitations of Liability before using this product. If terms 

are not acceptable, return the unopened product container al once. 

By using this product, user or buyer accepts the following Concf'ltions, Disclaimer of Warranties and limitations of l.iability. 

CONDITIONS: The directions for use of this product are believed to be adequate and must be followed carefully. However, it is 

impossible to eliminale atl risks associated with the use of this product. Crop injury, ineffectiveness or other unintended consequences 

may result because of such factors as weather conditions, presence of other materials, or the manner of use or application, all of which 

are beyond the control of Bayer CropScience. All such risks shat! be assumed by the user or buyer. 

DISCLAIMER OF WARRANTIES; TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, BAYER CROP SCIENCE MAKES NO 

OTHER WARRANTIES, EXPRESS OR IMPLIED, OF MERCHANTABILITY OR OF FITNESS FOR A PARTICULAR PURPOSE OR 

OTHERVVlSE, THAT EXTEND BEYOND THE STATEMENTS MADE ON THIS LABEL. No agent of Bayer CropScienoo Is authorized 10 

make any warranfles beyond Ihose conlained herein or 10 modify Ihe warranlies conlained herein. TO THE EXTENT CONSISTENT 

WITH APPLICABLE LAW, BAYER CROPSCIENCE DISCLAIMS ANY LIABILITY WHATSOEVER FOR SPECIAL, INCIDENTAL OR 

CONSEQUENTIAL DAMAGES RESULTING FROM THE USE OR HANDliNG OF THIS PRODUCT. 

LIMITATIONS OF UABILlTY: TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, THE EXCLUSIVE REMEDY OF THE 

USER OR BUYER FOR ANY AND ALL LOSSES, INJURIES OR DAMAGES RESULTING FROM THE USE OR HANDLING OF THIS 

PRODUCT, WHETHER IN C~T, ~, TORT, NEGUGENCE, STRICT UABllITY OR OTHERWSE, SHALl. NOT EXCEED THE 

PURCH4.SE PRICE PAID. DRAT M YER CROPSCIENCE'S 8.ECTION, THE REPlACEMENT OF PRODUCT. 

NET CONTENTS: 2.5 GALLONS 

Dropp, Ginslar, Def and Gulhion are regislered Irademarks and Prep and Ultra are trademarks of Bayer. 

Folex is a registered Irademark of Amvac Chemical Corporalion. 

Harvade is a regislered trademark of Uniroyal Company. 

Malalhion is a Irademark of American Cyanamid Company. 

Bayer CropScience lP 

P.O. Box 12014, 2 T.W. Alexander Drive 

Research Triangle Park. North Carolina 27709 

1·866-99BAVER (1-866-992-2937) 

PREpTM brand Elhephon for Cotton and Tobacco (PENDING) 05/24110, Resubmitted 06/01/10 

9 
Baver Crop Science 

May 20,2010 

Document Processing Desk (AMEND) 

Office of Pesticide Program (H7504P) 

U.S. EPA, Room S4900 

One Potomac Yard 

Arlington, VA 22202 -4525 

ATTN: Mr. Tony Kish (PM 22) 

Registration Division (750SP) 

Subject: PREP brand Ethephon for Cotton and Tobacco (Reg. No.: 264-418): 

Submission of the Application of Pesticide Notification mlder PR Notice 2007-4 (Ref.: 

the Pesticide Container and Containment Final Rule, August 16, 2006) 

Dear Mr. Kish: 

Bayer CropScience herein submits this amendment for the PREP brand Ethephon for 

Cotton and Tobacco (Reg. No.: 264-418), a soluti~n containing ethephon as the active 

ingredient. The amendment is to comply with the label language required by the regulation 

in 40 CFR part 156 established by the Final Rule "Pesticide Management and Disposal; 

Standards for Pesticide Container and Containment" (August 16, 2006). Based on the 

Guidance issued under the PR Notice 2007-4 and the product-specific information. we 

propose the following "Container Disposal" labeling (see Section for "Storage and 

Disposal"); 

CONTAINER DISPOSAL 

Rigid, Non-refillable containers small enough to shake (I.e., with capacities equal to or less than 5 gallons) 

Non-refillable container. Do not reuse or refilllhis container. Offer for recycling, if available. Triple rinse or pressure rinse 

container (or equivalent) promptly after emptying. Triple rinse as foDows: Empty the remaining contents into application 

equlpmenl or a mix tank and drain for 10 seconds after the flow begins to drip. Fill the container tl4 full with water and 

recap. Shake for 10 seconds. Pour rinsale into application equipment or a mix \;Ink or store rinsale for later use or disposal. 

Ot;:lin for 10 seconds after the flow begins to drip. Repeat this procedure two more times. Once container is rinsed, offer for 

recycling if ava~able or puncture and dispose of in a sanitary landfill. 

51

Baver Crop Science 

May 20,2010 

Document Processing Desk (AMEND) 

Office of Pesticide Program (H7504P) 

U.S. EPA, Room S4900 

One Potomac Yard 

Arlington, VA 22202 -4525 

ATTN: Mr. Tony Kish (PM 22) 

Registration Division (750SP) 

Subject: PREP brand Ethephon for Cotton and Tobacco (Reg. No.: 264-418): 

Submission of the Application of Pesticide Notification mlder PR Notice 2007-4 (Ref.: 

the Pesticide Container and Containment Final Rule, August 16, 2006) 

Dear Mr. Kish: 

Bayer CropScience herein submits this amendment for the PREP brand Ethephon for 

Cotton and Tobacco (Reg. No.: 264-418), a soluti~n containing ethephon as the active 

ingredient. The amendment is to comply with the label language required by the regulation 

in 40 CFR part 156 established by the Final Rule "Pesticide Management and Disposal; 

Standards for Pesticide Container and Containment" (August 16, 2006). Based on the 

Guidance issued under the PR Notice 2007-4 and the product-specific information. we 

propose the following "Container Disposal" labeling (see Section for "Storage and 

Disposal"); 

CONTAINER DISPOSAL 

Rigid, Non-refillable containers small enough to shake (I.e., with capacities equal to or less than 5 gallons) 

Non-refillable container. Do not reuse or refilllhis container. Offer for recycling, if available. Triple rinse or pressure rinse 

container (or equivalent) promptly after emptying. Triple rinse as foDows: Empty the remaining contents into application 

equlpmenl or a mix tank and drain for 10 seconds after the flow begins to drip. Fill the container tl4 full with water and 

recap. Shake for 10 seconds. Pour rinsale into application equipment or a mix \;Ink or store rinsale for later use or disposal. 

Ot;:lin for 10 seconds after the flow begins to drip. Repeat this procedure two more times. Once container is rinsed, offer for 

recycling if ava~able or puncture and dispose of in a sanitary landfill. 
Rigtd NOMefillable containers that aM too targe to shake (I.e., with capac/ties greater than 5 gallons or 50 Ibs) 

Non·refUtable Containers 

Non-refillable containers· 00 not reuse or rer~lthis container. Refer to Bottom Oi!>Charge IBC or Top Discharge IBC, Drums, 

Kegs infonnalion as follows. 

Bottom OisCharge IBC (e.g. - Schuetz Caged IBC or Snyder Square Stackable) 

Pressure rinsing the container before final disposal is the rasponsibi~ty of the person disposing of the container. To pressure 

r1nse the container before final disposal, empty the remaining contents from the IBC into applicallon equipment or mix tank. 

Raise the bottom of the IBC by t.5 inches on the side which is opposite of the bottom discharge valve to promote more 

complete product removal. Completely remove the top lid of the IBC. Use water pressurized to atleast40 PSI to rinse all 

interior portions. COntinuously pump or drain rinsate into application equipment or rinsate collection system while pressure 

rinsing. ConfinuG pressure rinsing for 2 minutes or until rinsate becomes clear. Replace the lid and close boHom valve. 

Top Discharge IBC, Drums, Kegs (e.g.- Snyder t20 Next Gen, Bonar B120, Drums. Kegs). 

Triple rinsing the container before fmat disposal Is the responsibility of the person d"lSposing of the container. To triple rinse 

the conlainerbeforefinal disposal; empty the H!maining contents from this container into application equipment ormix tank. 

FlU the container at /east 10 percent full with water. Agitate vigorously or recirculate water with the pumP for 2 minutes. 

RInse all Interior surfaces. Pour or pump rlnsate into application equipment or rinsate collection system. Repeat this 

procedure two more times. Once container is rinsed, offer for recycling if available or puncture and dl$p05e of in a sanitary 

landrdl. 

Refillable Containers 

ReffllabJe contalner- Refer to Bottom Discharge IBC or Top Discharge IBC, Drums. Kegs information as foDows. Refillihis 

container with pesticide only. Do not reuse this container for any other purpose. Afteremptying product from container,either 

retum con!a'lnerto BayerCropScience per instructions from Bayer CropScience Customer Service Genter (1-800·527-4781) 

or rinse and either recycle or dispose of the container as follows: 

Bottom Discharge IBC (e.g. - Schuetz Caged IBC or Snyder Square Stacl<able) 

Pressure rinsing the coriainer before fmal d"HlPO$al Is the responslbUIly of the person dispOSing of the container. Cleaning 

before refining is the responsibility of the refiller. To pressure rinse the contalner before fmal disposal, empty the remaining 

contents from the lac into application equipment or mix tank. Raise the bottom of the !BC by 1.5 inches on the side which is 

opposite of the bottom discharge valve to promote more complete product removal. Completely remove the top lid of the 

IBC. Use water pressurized to at least 40 PSI to rinse all interior portions. Continuously pump or drain rinsate into 

application equipment or rinsate collection system while pressure rinsing. ContinUe pressure rinsing for 2 minutes or unm 

rinsate becomes dear. Replace the lid and close bottom valve. 

Top Oi!>Charge IBC, Drums, Kegs (e.g.-Snyder 120 Next Gen, Bonar B t20, Drums, Kegs). 

Triple rinsing the container before final disposal is the responsibaity of the person disposing of the conJainer. Cleaning 

before refining is the responsibility of the refiller. To triple rinse the containers before final disposal, empty the remaining 

contents from this conlainerlnto application equipment or mix tank. Fill the container al least 10 percent full with water. 

Agitate vigorously or recirculate water wilh the pump for 2 minutes. Rinse all interior surfaces. Pour or pump rinsate into 

application equipmont orrinsale collection system. Repeat this procedure two more times. Once container is rinsed, offer for 

recycling if available orpunclure and dispose of in a sanitary landfill. 

Ritlfllable Containers 

End users are authorized to remove tamper evident cables as required to remove the product from the container unless the 

container is equipped with one way valves and refilling or retumlng is planned. If this is the case, end users are not 

authorized to remove tamper evident cables, one way valves or clean container. See Container Disposal instructions under 

Storage and Disposal. 

Enclosed is an EPA Fonn 8570~1, one copy of the revised PREP brand Ethephon for Cotton 

and Tobacco (Reg, No.: 264~418) label for review, and an extra page (witb the Container 

Disposal Section) where the revised/new text is highlighted. 

This amendment is consistent with the guidance in PR Notice Z007~4 and EPA's 

alternative language acceptance letter to Bayer CropScience dated November 10, Z009. No other 

changes have been made to the labeling or the Confidential Statement of Formula for this product. 

I understand that it is a violation of 18 U.S.c. Section 1001 to willfully make any false statement to 

2 

52

Rigtd NOMefillable containers that aM too targe to shake (I.e., with capac/ties greater than 5 gallons or 50 Ibs) 

Non·refUtable Containers 

Non-refillable containers· 00 not reuse or rer~lthis container. Refer to Bottom Oi!>Charge IBC or Top Discharge IBC, Drums, 

Kegs infonnalion as follows. 

Bottom OisCharge IBC (e.g. - Schuetz Caged IBC or Snyder Square Stackable) 

Pressure rinsing the container before final disposal is the rasponsibi~ty of the person disposing of the container. To pressure 

r1nse the container before final disposal, empty the remaining contents from the IBC into applicallon equipment or mix tank. 

Raise the bottom of the IBC by t.5 inches on the side which is opposite of the bottom discharge valve to promote more 

complete product removal. Completely remove the top lid of the IBC. Use water pressurized to atleast40 PSI to rinse all 

interior portions. COntinuously pump or drain rinsate into application equipment or rinsate collection system while pressure 

rinsing. ConfinuG pressure rinsing for 2 minutes or until rinsate becomes clear. Replace the lid and close boHom valve. 

Top Discharge IBC, Drums, Kegs (e.g.- Snyder t20 Next Gen, Bonar B120, Drums. Kegs). 

Triple rinsing the container before fmat disposal Is the responsibility of the person d"lSposing of the container. To triple rinse 

the conlainerbeforefinal disposal; empty the H!maining contents from this container into application equipment ormix tank. 

FlU the container at /east 10 percent full with water. Agitate vigorously or recirculate water with the pumP for 2 minutes. 

RInse all Interior surfaces. Pour or pump rlnsate into application equipment or rinsate collection system. Repeat this 

procedure two more times. Once container is rinsed, offer for recycling if available or puncture and dl$p05e of in a sanitary 

landrdl. 

Refillable Containers 

ReffllabJe contalner- Refer to Bottom Discharge IBC or Top Discharge IBC, Drums. Kegs information as foDows. Refillihis 

container with pesticide only. Do not reuse this container for any other purpose. Afteremptying product from container,either 

retum con!a'lnerto BayerCropScience per instructions from Bayer CropScience Customer Service Genter (1-800·527-4781) 

or rinse and either recycle or dispose of the container as follows: 

Bottom Discharge IBC (e.g. - Schuetz Caged IBC or Snyder Square Stacl<able) 

Pressure rinsing the coriainer before fmal d"HlPO$al Is the responslbUIly of the person dispOSing of the container. Cleaning 

before refining is the responsibility of the refiller. To pressure rinse the contalner before fmal disposal, empty the remaining 

contents from the lac into application equipment or mix tank. Raise the bottom of the !BC by 1.5 inches on the side which is 

opposite of the bottom discharge valve to promote more complete product removal. Completely remove the top lid of the 

IBC. Use water pressurized to at least 40 PSI to rinse all interior portions. Continuously pump or drain rinsate into 

application equipment or rinsate collection system while pressure rinsing. ContinUe pressure rinsing for 2 minutes or unm 

rinsate becomes dear. Replace the lid and close bottom valve. 

Top Oi!>Charge IBC, Drums, Kegs (e.g.-Snyder 120 Next Gen, Bonar B t20, Drums, Kegs). 

Triple rinsing the container before final disposal is the responsibaity of the person disposing of the conJainer. Cleaning 

before refining is the responsibility of the refiller. To triple rinse the containers before final disposal, empty the remaining 

contents from this conlainerlnto application equipment or mix tank. Fill the container al least 10 percent full with water. 

Agitate vigorously or recirculate water wilh the pump for 2 minutes. Rinse all interior surfaces. Pour or pump rinsate into 

application equipmont orrinsale collection system. Repeat this procedure two more times. Once container is rinsed, offer for 

recycling if available orpunclure and dispose of in a sanitary landfill. 

Ritlfllable Containers 

End users are authorized to remove tamper evident cables as required to remove the product from the container unless the 

container is equipped with one way valves and refilling or retumlng is planned. If this is the case, end users are not 

authorized to remove tamper evident cables, one way valves or clean container. See Container Disposal instructions under 

Storage and Disposal. 

Enclosed is an EPA Fonn 8570~1, one copy of the revised PREP brand Ethephon for Cotton 

and Tobacco (Reg, No.: 264~418) label for review, and an extra page (witb the Container 

Disposal Section) where the revised/new text is highlighted. 

This amendment is consistent with the guidance in PR Notice Z007~4 and EPA's 

alternative language acceptance letter to Bayer CropScience dated November 10, Z009. No other 

changes have been made to the labeling or the Confidential Statement of Formula for this product. 

I understand that it is a violation of 18 U.S.c. Section 1001 to willfully make any false statement to 

2 
EPA. I further understand that iftbe amended label is not consistent witb tbe requirements of 40 

CFR §§ 156.10, 156.140, 156.144, 156.146 and 156.156, this product may be in violation of FIFRA 

and I may be subjected to enforcement action and penalties under Section 12 and 14 of FIPRA". 

Please contact me if you should have further questions. 

Sincerely, 

daUlk 

Laura Phelps 

Regulatory Affairs, Herbicides & PGRs 

Bayer CropScience 

2 T. W. Alexander Drive 

RTP, NC 27709 

office: 919~549-2302 

mobil:9 I 9-352-8075 

email;laura.phelps@bayercropscience.com 

3 

53

EPA. I further understand that iftbe amended label is not consistent witb tbe requirements of 40 

CFR §§ 156.10, 156.140, 156.144, 156.146 and 156.156, this product may be in violation of FIFRA 

and I may be subjected to enforcement action and penalties under Section 12 and 14 of FIPRA". 

Please contact me if you should have further questions. 

Sincerely, 

daUlk 

Laura Phelps 

Regulatory Affairs, Herbicides & PGRs 

Bayer CropScience 

2 T. W. Alexander Drive 

RTP, NC 27709 

office: 919~549-2302 

mobil:9 I 9-352-8075 

email;laura.phelps@bayercropscience.com 

3 
oEPA 

Number 

) 

... Unlad swe .. 

Environmental Protection Agency 

W .. hinglon. oc 20480 

-:-7 Registration :E: Amendment 

Other 

lIor 1- ,I 

I ~ .. EP!'. P~,.' ........ I !VII. I~II! Kish 

P .... 

PM Team #22 

3. I"fCllloelNf Clo .. lfic:.tion 

DNOM D R.mictH 

5. N_.and ~ of App&IN~ (lnrmw. m 0>., 

Bayer CropScience; 

P.D, Box 12014,2 T.W.AlexanderOrive; 

Research Trlanqre Park, NC 27709 

6. Expedited Review, In aceordanca with FIFRA Section 3/eIl3) I !~~(il, my product i$ similar Of idemfcalln composition and labeling 

II EPA Reg. No. ______________ _ 

D Chm H thi8 J." _w eddr_ 

~-ll 

BayerCropScience would like to add the required container disposal language to the PREP brand Ethephon for Cotton and Tobacco 

label per PR Notice 2007-4 

, - t. • .......... WII .. 

......... Packaging 2. Type of C4nUllner 

v,,- r- Yu 

tis N. ~ N. 

"" :;. c::=::::; mus' 

~~--"",---+¥V-,::-:'---::----I ;'::!'-. ..... _..." ..... ..... § E- P.or '",,".'",Wgl. • ....... ':!'. :!. wgl ......... !'. 01htr'S."1fv

, ______ 1 

, 

1;3~'~ ........ 1-:_~M._::_"._"_-_._,,_E __ ._A_ .. _X_ ... _"'_,,_ .... _,_t _2 .. ~-;95;30;2209 D "'''" ______ _ 

-IV 

• C"""" Pol .. 

:':':'Ph'(PS 

r ... 

Reg. Affairs SpecialIst 

Certification 

f clltl'fy tnllt the .wamenu f navo made on thic. fOIm end ell ottachmont$ thereto .,a Uue, lIcc:"rat, end c.ompfatto. 

I acknowledg' (n.t any knewinglv fill .. or mill,odinD It&tem,nt mtvbe puriatllabl, by Ii"" 01 ~rl.onm.nt or 

both under .... 

14. Typed Nwnt 

laura Phelps 

.. A ....... 7 .. " ........ " • editions 0'0 

3. nUl 

Reg. Affairs Specialist 

5. D.n. 

20 May 2010 

Whhf, • EPA file Copy loriglnill 

No. Clno{ude Atu Code' 

e. Dele Applic.tien 

Received 

fStamped) 

y.vow • AppffQnt CopV 

54

) 

... Unlad swe .. 

Environmental Protection Agency 

W .. hinglon. oc 20480 

Registration 

Amendment 

Other 

,. , Number 

5. N_.and ~ of App&IN~ (lnrmw. m 0>., 

Bayer CropScience; 

P.D, Box 12014,2 T.W.AlexanderOrive; 

Research Trlanqre Park, NC 27709 

D Chm H thi8 J." _w eddr_ 

o Am.ndlTlfnt· ~.n below. 

lIor , -

2. EPA Product Manag.r 

Mr. Tony Kish 

P .... 

PM Team #22 

6. Expedited Review, In aceordanca with FIFRA Section 3/eIl3) 

(blli), my product i$ similar Of idemfcalln composition and labeling 

1'0' II EPA Reg. No. ______________ _ 

I -~I 

-, 

_I FiMl printM I"'" ill "'P0ntl. to o R,submI..ton In "'POn •• 10 Agency fen., d.1ed _____ _ 

:= A~novl.mld.ted ____________ 1 

-Mo Too" AppIlQ81ion. 

o Nolfl'lc.uon - fJrpIaln ~ow. = Oth., - Explain I*ow. 

BayerCropScience would like to add the required container disposal language to the PREP brand Ethephon for Cotton and Tobacco 

label per PR Notice 2007-4 

1;m~--------------4 

........... WII .. 

r- Yu - v .. 

t;<" N. K N. 

wgt. 

No. po, 

contaiMI 

'-Yu" ..., 

, 

,., 

~ Lab" 0 Conteln.r 

6. M.nner in Which Lebel " Affix-lid to Ptoduct j;3 ~!:r.:~~ 

I-----~ -IV 

25;95;30;22°9 

r ... 

No. p{t1 contaira, 

2. Type of C4nUllner 

§=-

Ptpor 

01htrIS'''''~I _______ 1 

fL'~'~ " .... " D "'''" ______ _ 

1_ C""",. P .... 

:':':'Ph'(PS Reg. Affairs SpecialIst 

No. Clt\OfUd. Atu Code' 

14. Typed NII'I'It 

laura Phelps 

IPA""""'o-, ' ........ 1, • Ridons oro 

Certification 

5. D/rtt 

20 May 2010 

,Cop, I YoU ... .~, 
UNITED STATES ENVIRONMENTAL PROTECTION AGENCY 

WASHINGTON. D.C. 20460 

November 10, 2009 

Mr. Mel Tolliver 

Bayer CropScience LP 

2 T.W, Alexander Drive, 

Research Triangle Park, NC 27709 

OFFICE OF 

PREVENTION, PESTICIDES 

"""""","",,,-:c=,._..ANo..TOXIC SUBSTANCES 

rclWUC2 !]: [: IT" i'l ~~'- lCo co ' d '!"I 

I~I' NOV 192009 il': Ui , '; , ... i 

By, _I 

Subject: EPA accepted Bayer CropScience label template with modified container 

disposal and residue removal language 

Dear Mr. Tolliver: 

Pursuant to 40, CFR 156,140(c) and 156,144(d), Bayer CropSc!ence (8CS) 

requested modifications to the container disposal and residue removal language in 40 

CFR part 156 and PR Notice 2007~4. EPA has reviewed BGS's proposed label 

Instructions on handling, rinsing and disposal of both nonrefillable and refillable 

contaIners of seed treatment and non~seed treatment products and has determined that 

the language in Attachment 1 Is acceptable and that label amendments incorporating the 

language in Attachment 1 can be approved. Please note that two editorial changes have 

been made to your October 10,2009 draft by (1) inserting the word "by" before 

"incineration" in the last sentence under the heading "Non~refmable Containers" for seed 

treatment products and (2) changing L~nch" to "inchesR where instructions say to ~Raise 

the bottom of the IBC by 1.5 inch ... " 

Although EPA believes that these alternative statements could be suitable for 

various pesticide products, this letter is not an approval of the use of such statements on 

any particular product. In order to use these statements on a pesticide product label, . 

you must apply for amendment of the product registration. Such applications must 

conform to the requirements of 40 CFR 152.44 since the language is not the exact 

wording as in the statements in 40 CFR Part 156.140 through 156.156. 

The following is a summary 01 the changes accepted by EPA: 

1) Identification of Container Type Statements 

The federal regulations in §156.140(c) allow EPA to modify or waive the 

requirements, or permit or require alternative labeling statements, for the 

"Identification of container type" statements that include a recycling or 

reconditioning statement. EPA is allowing BCS to use a statement for seed 

treatment products in nonrefillable containers that is different than the standard 

recycling or reconditioning statements provided in §156.140(a)(3). 

55

UNITED STATES ENVIRONMENTAL PROTECTION AGENCY 

WASHINGTON. D.C. 20460 

November 10, 2009 

Mr. Mel Tolliver 

Bayer CropScience LP 

2 T.W, Alexander Drive, 

Research Triangle Park, NC 27709 

OFFICE OF 

PREVENTION, PESTICIDES 

"""""","",,,-:c=,._..ANo..TOXIC SUBSTANCES 

rclWUC2 !]: [: IT" i'l ~~'- lCo co ' d '!"I 

I~I' NOV 192009 il': Ui , '; , ... i 

By, _I 

Subject: EPA accepted Bayer CropScience label template with modified container 

disposal and residue removal language 

Dear Mr. Tolliver: 

Pursuant to 40, CFR 156,140(c) and 156,144(d), Bayer CropSc!ence (8CS) 

requested modifications to the container disposal and residue removal language in 40 

CFR part 156 and PR Notice 2007~4. EPA has reviewed BGS's proposed label 

Instructions on handling, rinsing and disposal of both nonrefillable and refillable 

contaIners of seed treatment and non~seed treatment products and has determined that 

the language in Attachment 1 Is acceptable and that label amendments incorporating the 

language in Attachment 1 can be approved. Please note that two editorial changes have 

been made to your October 10,2009 draft by (1) inserting the word "by" before 

"incineration" in the last sentence under the heading "Non~refmable Containers" for seed 

treatment products and (2) changing L~nch" to "inchesR where instructions say to ~Raise 

the bottom of the IBC by 1.5 inch ... " 

Although EPA believes that these alternative statements could be suitable for 

various pesticide products, this letter is not an approval of the use of such statements on 

any particular product. In order to use these statements on a pesticide product label, . 

you must apply for amendment of the product registration. Such applications must 

conform to the requirements of 40 CFR 152.44 since the language is not the exact 

wording as in the statements in 40 CFR Part 156.140 through 156.156. 

The following is a summary 01 the changes accepted by EPA: 

1) Identification of Container Type Statements 

The federal regulations in §156.140(c) allow EPA to modify or waive the 

requirements, or permit or require alternative labeling statements, for the 

"Identification of container type" statements that include a recycling or 

reconditioning statement. EPA is allowing BCS to use a statement for seed 

treatment products in nonrefillable containers that is different than the standard 

recycling or reconditioning statements provided in §156.140(a)(3). 
2) Pressure~rinsing Instructions for Nonrefillable Containers that are Bottom 

Discharge IBCs 

The federal regulations in § t56.144 allow EPA to modify or waive the 

requirements, or permit or require alternative labeling statements, for residue 

removal instructions, BCS asserts that the standard residue removal instructions 

for nonrefillable containers that are too large to shake are impractical for the 

nonrefillable bottom discharge IBCs. Therefore, EPA is allowing BCS to use its 

own pressure-rinsing instructions, rather than the options in §t56.146(c), for both 

seed and non-seed treatment products in rigid, nonrefillable containers that are 

Bottom Discharge IBCs. 

3) Triple-rinsing Instructions for Nonrefillable Containers that are Top Discharge 

18Cs, Drums and Kegs 

The federal regulations in §156.144 allow EPA to modify or waive the 

requirements, or permit or require alternative labeling statements, for residue 

removal instructions. BCS asserts that the standard residue removal instructions 

(in § t56.146) for nonrefillable containers that are too large to shake are 

impractical. Therefore, EPA is allowing BCS to use its own trlple~rinsing 

instructions. The BCS triple~rinsing instructions are the same for both seed and 

non-seed treatment products in rigid, nonrefillable containers that are Top 

Discharge IBCs, Drums, or Kegs. 

4) Rinsing Instructions for Refillable Containers 

The federal regulations in § t56. t56 require instructions on labels of 

refillable containers for rinsing the container prior to disposal, which must be 

appropriate for the characteristics and formulation of the pesticide product and 

adequate to protect human health and the environment. The regulations provide 

several options for these cleaning instructions prior to disposal, including "any 

other statement the registrant considers appropriate". Because the container 

designs are the same for refillable containers and nonrefillable containers, EPA is 

allowing BGS to use the for the refillable 

bottom discharge IBCs IBCs and the 

same triple rinsing statements for 

kegs as for the nonrefillable top discharge I 

5) Other Changes to the Container HandUng Instructions 

Although not required in §156. t40(b) EPA is allowing BGS to add a 

recycling or reconditioning statement for refillable containers. In addition, BGS 

has Indicated that it intends to delete the references to buming, as suggested by 

EPA. 

6) Directions for Use 

Lastly, although not required, EPA is allowing BCS to add text to the 

directions for use on the labels of seed and non-seed treatment products In 

refillable containers that allow the user to remove tamper evident cables unless 

the container has one~way valves and will be refilled or returned. 

Attachment 2 explains the differences in more detail between statements in the 

federal regulations and the BCS template label. 

2 

56

2) Pressure~rinsing Instructions for Nonrefillable Containers that are Bottom 

Discharge IBCs 

The federal regulations in § t56.144 allow EPA to modify or waive the 

requirements, or permit or require alternative labeling statements, for residue 

removal instructions, BCS asserts that the standard residue removal instructions 

for nonrefillable containers that are too large to shake are impractical for the 

nonrefillable bottom discharge IBCs. Therefore, EPA is allowing BCS to use its 

own pressure-rinsing instructions, rather than the options in §t56.146(c), for both 

seed and non-seed treatment products in rigid, nonrefillable containers that are 

Bottom Discharge IBCs. 

3) Triple-rinsing Instructions for Nonrefillable Containers that are Top Discharge 

18Cs, Drums and Kegs 

The federal regulations in §156.144 allow EPA to modify or waive the 

requirements, or permit or require alternative labeling statements, for residue 

removal instructions. BCS asserts that the standard residue removal instructions 

(in § t56.146) for nonrefillable containers that are too large to shake are 

impractical. Therefore, EPA is allowing BCS to use its own trlple~rinsing 

instructions. The BCS triple~rinsing instructions are the same for both seed and 

non-seed treatment products in rigid, nonrefillable containers that are Top 

Discharge IBCs, Drums, or Kegs. 

4) Rinsing Instructions for Refillable Containers 

The federal regulations in § t56. t56 require instructions on labels of 

refillable containers for rinsing the container prior to disposal, which must be 

appropriate for the characteristics and formulation of the pesticide product and 

adequate to protect human health and the environment. The regulations provide 

several options for these cleaning instructions prior to disposal, including "any 

other statement the registrant considers appropriate". Because the container 

designs are the same for refillable containers and nonrefillable containers, EPA is 

allowing BGS to use the for the refillable 

bottom discharge IBCs IBCs and the 

same triple rinsing statements for 

kegs as for the nonrefillable top discharge I 

5) Other Changes to the Container HandUng Instructions 

Although not required in §156. t40(b) EPA is allowing BGS to add a 

recycling or reconditioning statement for refillable containers. In addition, BGS 

has Indicated that it intends to delete the references to buming, as suggested by 

EPA. 

6) Directions for Use 

Lastly, although not required, EPA is allowing BCS to add text to the 

directions for use on the labels of seed and non-seed treatment products In 

refillable containers that allow the user to remove tamper evident cables unless 

the container has one~way valves and will be refilled or returned. 

Attachment 2 explains the differences in more detail between statements in the 

federal regulations and the BCS template label. 

2 
EPA recommends that, in order to facilitate the review of revised labels, you 

include a copy of this letter and the relevant page(s) from Attachment t each time you 

submit an amendment regarding the container handling, rinsing and disposal 

statements. 

If you have any questions, please feel free to contact me at 

kasai.jeanne@epa.gov or (703) 308·3240 or Nancy Fltz at fitz.nancy@epa.govor(703) 

305·7385. 

cc: Heather Garvie 

Nancy Fitz 

Tony Kish 

Enclosures: 

Sincerely, 

d::t~ Field and External Affairs Division 

Attachment 1. Bayer CropScience Label Template for Container Handl'lng and Disposal 

Statements (§§156,140 -156,156) Accepted by EPA as of November 2009 

Attachment 2. Differences between statements provided in 40 CFR part 156 and 

PR Notice 2007-4, and BCS statements accepted by EPA as of November 2009 

3 

57

EPA recommends that, in order to facilitate the review of revised labels, you 

include a copy of this letter and the relevant page(s) from Attachment t each time you 

submit an amendment regarding the container handling, rinsing and disposal 

statements. 

If you have any questions, please feel free to contact me at 

I or (703) 308·3240 or Nancy Fltz at fitz.nancy@epa.govor(703) 

cc: Heather Garvie 

Nancy Fitz 

Tony Kish 

Enclosures: 

Sincerely, 

d::t~ Field and External Affairs Division 

Attachment 1. Bayer CropScience Label Template for Container Handl'lng and Disposal 

Statements (§§156,140 -156,156) Accepted by EPA as of November 2009 

Attachment 2. Differences between statements provided in 40 CFR part 156 and 

PR Notice 2007-4, and BCS statements accepted by EPA as of November 2009 

3 
Attachment 1 

• Page 1 of4-

Bayer CropScience Label Template for Container Handling and Disposal 

Statement. (§§156.140-156.156) Accepted by EPA •• of November 2009 

Seed Treatment Products 

Rigid Non-refillable containers that are too large to shake (l.e'J with capacities 

greater than 5 gallons or 50 Ibs) 

Non-refillable Containers 

Non-refillable containers - Do not reuse or refill this container. After emptying product 

from container, either return container to Bayer CropSclence per instructions from Bayer 

CropScience Customer Service Center (1-800-527-4781), or rinse and either recycle or 

dispose ot the container as follows: 

Bottom Discharge IBC (e.g. - Schuetz Caged IBC or Snyder Square Stackable) 

Pressure rinsing the container before final disposal is the responsibility of the person 

disposing of the container. To pressure rinse the container before linal disposal, 

empty the remaining contents from the IBC Into application equipment or mix tank. 

Raise the bottom of the IBC by 1 .5 inches on the side which is opposite of the bottom 

discharge valve to promote more complete product removal. Completely remove the 

top Ud of the IBC. Use water pressurized to at least 40 PSI to rinse all Interior 

portions. Continuously pump or drain rinsate into application equipment or rinsate 

collection system while pressure rinsing. Continue pressure rinsing for 2 minutes or 

until rinsate becomes clear. Replace the lid and close bottom valve. 

TOp Discharge IBC, Drums, Kegs (e.9.- Snyder 120 Next Gen, Bonar 8120, Drums, and 

Kegs). 

Triple rinsing the container before final disposal is the responsibility of the person 

disposing of the container. To triple rinse the container before final disposal, empty 

the remaining contents trom this container into application equipment or mix tank. Fill 

the container at least 10 percent full with water. Agitate vigorously or recirculate water 

with the pump for 2 minutes. Rinse all interior suriaces. Pour or pump rinsate into 

application equipment or rinsate collection system. Repeat this procedure two more 

times. 

Once container is rinsed, offer for recycling if available or puncture and dispose of in a 

sanitary landfill, or by incineration. 

58

Attachment 1 

• Page 1 of4-

Bayer CropScience Label Template for Container Handling and Disposal 

Statement. (§§156.140-156.156) Accepted by EPA •• of November 2009 

Seed Treatment Products 

Rigid Non-refillable containers that are too large to shake (l.e'J with capacities 

greater than 5 gallons or 50 Ibs) 

Non-refillable Containers 

Non-refillable containers - Do not reuse or refill this container. After emptying product 

from container, either return container to Bayer CropSclence per instructions from Bayer 

CropScience Customer Service Center (1-800-527-4781), or rinse and either recycle or 

dispose ot the container as follows: 

Bottom Discharge IBC (e.g. - Schuetz Caged IBC or Snyder Square Stackable) 

Pressure rinsing the container before final disposal is the responsibility of the person 

disposing of the container. To pressure rinse the container before linal disposal, 

empty the remaining contents from the IBC Into application equipment or mix tank. 

Raise the bottom of the IBC by 1 .5 inches on the side which is opposite of the bottom 

discharge valve to promote more complete product removal. Completely remove the 

top Ud of the IBC. Use water pressurized to at least 40 PSI to rinse all Interior 

portions. Continuously pump or drain rinsate into application equipment or rinsate 

collection system while pressure rinsing. Continue pressure rinsing for 2 minutes or 

until rinsate becomes clear. Replace the lid and close bottom valve. 

TOp Discharge IBC, Drums, Kegs (e.9.- Snyder 120 Next Gen, Bonar 8120, Drums, and 

Kegs). 

Triple rinsing the container before final disposal is the responsibility of the person 

disposing of the container. To triple rinse the container before final disposal, empty 

the remaining contents trom this container into application equipment or mix tank. Fill 

the container at least 10 percent full with water. Agitate vigorously or recirculate water 

with the pump for 2 minutes. Rinse all interior suriaces. Pour or pump rinsate into 

application equipment or rinsate collection system. Repeat this procedure two more 

times. 

Once container is rinsed, offer for recycling if available or puncture and dispose of in a 

sanitary landfill, or by incineration. 
Attachment 1 

~ Page 2 of4~ 

Bayer CropSclence Label Template for Container Handling and Disposaf 

Statements (§§t56.t40-156.156) Accepted by EPA as of November 2009 

Seed Treatment Products in RefUlabfe Containers 

Refillable container. Refill this container with pesticide only. Do not reuse this container 

for any other purpose. After emptying product from container, either return container to 

Bayer CropSclence per instructions from Bayer CropScience Customer Service Center 

(1~800~527~4781) or rinse and either recycle or dispose of the container as follows: 

Bottom Discharge IBC (e.g. - Schuetz Caged IBC or Snyder Square Stackable) 

Pressure rinsing the container before final disposal is the responsibility of the person 

disposing of the container. Cleaning before refilling is the responsibility of the refiller. 

To pressure rinse the container before final disposal, empty the remaining contents 

from the IBC into application equipment or mix tank. Raise the bottom of the IBC by 

1.5 inches on the side which is opposite of the bottom discharge valve to promote 

more complete product removal. Completely remove the top lid of the IBC. Use water 

pressurized to at least 40 PSI to rinse all interior portions. Continuously pump or drain 

rinsate into application equipment or rinsate collection system while pressure rinsing, 

Continue pressure rinsing for 2 minutes or until rinsate becomes clear. Replace the lid 

and close bottom valve, 

Top Discharge IBC, Drums, Kegs (e.g. - Snyder 120 Next Gen, Bonar B120, Drums, 

and Kegs). 

Triple rinsing the container before final disposal is the responsibility of the person 

disposing of the container. Cleaning before refilling is the responsibility of the refiller. 

To tripfe rinse the -containers before final disposal, empty the remaining contents from 

this container into application equipment or mix tank. Fill the container at least 10 

percent full with water. Agitate vigorously or recirculate water with the pump for 2 

minutes. Rinse all interior surfaces. Pour or pump r'rnsate into application equ'lpment 

or rinsate collection system. Repeat this procedure two more times, 

Once container is rinsed, offer for recycling if available or puncture and dispose of in a 

sanitary landfill or by incineration, 

Text to Add to Dfrectfons for Use on Labefs of Seed Treatment Products fn 

Refflfable Contafners 

Refflfable Containers 

End users are authorized to remove tamper evident cables as required to remove the 

product from the container unless the container is equipped with one way valves and 

refilling or returning is planned. ff this is the case, end users are not authorized to 

remove tamper evident cables, one way valves or clean container, See Container 

Disposal instructions under Storage and Disposal. 

59

Attachment 1 

~ Page 2 of4~ 

Bayer CropSclence Label Template for Container Handling and Disposaf 

Statements (§§t56.t40-156.156) Accepted by EPA as of November 2009 

Seed Treatment Products in RefUlabfe Containers 

Refillable container. Refill this container with pesticide only. Do not reuse this container 

for any other purpose. After emptying product from container, either return container to 

Bayer CropSclence per instructions from Bayer CropScience Customer Service Center 

(1~800~527~4781) or rinse and either recycle or dispose of the container as follows: 

Bottom Discharge IBC (e.g. - Schuetz Caged IBC or Snyder Square Stackable) 

Pressure rinsing the container before final disposal is the responsibility of the person 

disposing of the container. Cleaning before refilling is the responsibility of the refiller. 

To pressure rinse the container before final disposal, empty the remaining contents 

from the IBC into application equipment or mix tank. Raise the bottom of the IBC by 

1.5 inches on the side which is opposite of the bottom discharge valve to promote 

more complete product removal. Completely remove the top lid of the IBC. Use water 

pressurized to at least 40 PSI to rinse all interior portions. Continuously pump or drain 

rinsate into application equipment or rinsate collection system while pressure rinsing, 

Continue pressure rinsing for 2 minutes or until rinsate becomes clear. Replace the lid 

and close bottom valve, 

Top Discharge IBC, Drums, Kegs (e.g. - Snyder 120 Next Gen, Bonar B120, Drums, 

and Kegs). 

Triple rinsing the container before final disposal is the responsibility of the person 

disposing of the container. Cleaning before refilling is the responsibility of the refiller. 

To tripfe rinse the -containers before final disposal, empty the remaining contents from 

this container into application equipment or mix tank. Fill the container at least 10 

percent full with water. Agitate vigorously or recirculate water with the pump for 2 

minutes. Rinse all interior surfaces. Pour or pump r'rnsate into application equ'lpment 

or rinsate collection system. Repeat this procedure two more times, 

Once container is rinsed, offer for recycling if available or puncture and dispose of in a 

sanitary landfill or by incineration, 

Text to Add to Dfrectfons for Use on Labefs of Seed Treatment Products fn 

Refflfable Contafners 

Refflfable Containers 

End users are authorized to remove tamper evident cables as required to remove the 

product from the container unless the container is equipped with one way valves and 

refilling or returning is planned. ff this is the case, end users are not authorized to 

remove tamper evident cables, one way valves or clean container, See Container 

Disposal instructions under Storage and Disposal. 
Attachment 1 

~Page30f4· 

Bayer CropScience Label Template for Container Handling and Disposal 

Statements (§§156.140 -156.156) Accepted by EPA as of November 2009 

NOIl"'Seed Treatment Products 

Rigid Non-refillable containers that are too large to shake (I.e., with capacities 

greater than 5 gallons or 50 Ibs) 

Non-refillable Containers 

Non-refillable containers - Do not reuse or refill this container. Refer to Bottom 

Discharge IBC or Top Discharge IBC, Drums, Kegs information as follows. 

Bottom Discharge IBC (e.g. - Schuetz Caged IBC or Snyder Square Stackable) 

Pressure rinsing the container before final disposal is the responsibility of the person 

disposing of the container. To pressure rinse the container before final disposal, empty 

the remaining contents from the IBC into application equipment or mix tank. Raise the 

bottom of the IBC by 1.5 inches on the side which is opposite of the bottom discharge 

valve to promote more complete product removal. Completely remove the top lid of the 

IBC. Use water pressurized to at le'ast 40 PSI to rinse all interior portions. Continuously 

pump or drain rinsate into application equipment or rinsate collection system while 

pressure rinsing. Continue pressure rinsing for 2 minutes or until rinsate becomes 

clear. Replace the lid and close bottom valve. 

Top Discharge IBC, Drums, Kegs (e.g.- Snyder 120 Next Gen, Bonar B120, Drums, 

Kegs). 

Triple rinsing the container before final disposal is the responsibility of the person 

disposing of the container. To triple rinse the container before final disposal, empty the 

remaining contents from this container into application equipment or mix tank. Fill the 

container at least 10 percent full with water. Agitate vigorously or recirculate water with 

the pump for 2 minutes. Rinse all interior surfaces. Pour or pump rinsate Into 

application equipment or rinsate collection system. Repeat this procedure two more 

times. 

Once container Is rinsed, offer for recycling if available or puncture and dispose of in a 

sanitary landfill Or by incineration. 

60

Attachment 1 

~Page30f4· 

Bayer CropScience Label Template for Container Handling and Disposal 

Statements (§§156.140 -156.156) Accepted by EPA as of November 2009 

NOIl"'Seed Treatment Products 

Rigid Non-refillable containers that are too large to shake (I.e., with capacities 

greater than 5 gallons or 50 Ibs) 

Non-refillable Containers 

Non-refillable containers - Do not reuse or refill this container. Refer to Bottom 

Discharge IBC or Top Discharge IBC, Drums, Kegs information as follows. 

Bottom Discharge IBC (e.g. - Schuetz Caged IBC or Snyder Square Stackable) 

Pressure rinsing the container before final disposal is the responsibility of the person 

disposing of the container. To pressure rinse the container before final disposal, empty 

the remaining contents from the IBC into application equipment or mix tank. Raise the 

bottom of the IBC by 1.5 inches on the side which is opposite of the bottom discharge 

valve to promote more complete product removal. Completely remove the top lid of the 

IBC. Use water pressurized to at le'ast 40 PSI to rinse all interior portions. Continuously 

pump or drain rinsate into application equipment or rinsate collection system while 

pressure rinsing. Continue pressure rinsing for 2 minutes or until rinsate becomes 

clear. Replace the lid and close bottom valve. 

Top Discharge IBC, Drums, Kegs (e.g.- Snyder 120 Next Gen, Bonar B120, Drums, 

Kegs). 

Triple rinsing the container before final disposal is the responsibility of the person 

disposing of the container. To triple rinse the container before final disposal, empty the 

remaining contents from this container into application equipment or mix tank. Fill the 

container at least 10 percent full with water. Agitate vigorously or recirculate water with 

the pump for 2 minutes. Rinse all interior surfaces. Pour or pump rinsate Into 

application equipment or rinsate collection system. Repeat this procedure two more 

times. 

Once container Is rinsed, offer for recycling if available or puncture and dispose of in a 

sanitary landfill Or by incineration. 
Attachment 1 

~ page 4 of4-

Bayer CropSclence Label Template for Container Handling and Disposal 

Statements (§§156.140-156.156) Accepted by EPA as of November 2009 

Non Seed~ Treatment Products In Refillable Containers 

Relillable container - Reier to Bottom Discharge IBC or Top Discharge IBC, Drums, 

Kegs information as follows. Refill this container with pesticide only. Do not reuse this 

container for any other purpose. Contact your Ag retailer or Bayer CropScience for 

container return, disposal and recycling inlormation. 

Bottom Discharge IBC (e.g. - Schuetz Caged IBC or Snyder Square Stackable) 

Pressure rinsing the container before final disposal is the responsibility of the person 

disposing of the container. Cleaning before refilling is the responsibility of the refiller. 

To pressure rinse the container before final disposal, empty the remaining contents 

from the IBC into application equipment or mix tank. Raise the, bottom of the IBC by 

1.5 inches on the side which is opposite of the bottom discharge varve to promote 

more complete product removal. Completely remove the top lid of the IBC. Use water 

pressurized to at least 40 PSI to rinse all Interior portions. Continuously pump or drain 

rinsate into application equipment or rinsate collection system while pressure rinsing. 

Continue pressure rinsing for 2 minutes or until rinsate becomes clear. Replace the lid 

and close bottom valve. 

TOp Discharge IBC, Drums, Kegs (e.g.- Snyder 120 Next Gen, Bonar 8120, Drums, 

Kegs). 

Triple rinsing the container before final disposal is the responsibility of the person 

disposing of the container. Cleaning before refiRing is·the responsibility of the refiller. 

To triple rinse the containers before final disposal, empty the remaining contents from 

this container into application equipment or mix tank. Fill the container at least to 

percent full with water. Agitate vigorously or recirculate water with the pump for 2 

minutes. Rinse all interior surfaces. Pour or pump rinsate into application equipment 

or rinsate collection system. Repeat this procedure two more times. 

Once container is rinsed, offer for recycling if available or puncture and dispose of in a 

sanitary landfill or by inCineration. 

Text to Add to Directions for Use on Labels of Non-Seed Treatment Products In 

Refillable Containers 

End users are authorized to remove tamper evident cables as required to remove the 

product from the container unless the container is equipped with one way valves and 

refilling or returning is planned. If this is the case, end users are not authorized to 

remove tamper evident cables, one way valves or, clean container. See Container 

Disposal instructions under Storage and Disposal. 

61

Attachment 1 

~ page 4 of4-

Bayer CropSclence Label Template for Container Handling and Disposal 

Statements (§§156.140-156.156) Accepted by EPA as of November 2009 

Non Seed~ Treatment Products In Refillable Containers 

Relillable container - Reier to Bottom Discharge IBC or Top Discharge IBC, Drums, 

Kegs information as follows. Refill this container with pesticide only. Do not reuse this 

container for any other purpose. Contact your Ag retailer or Bayer CropScience for 

container return, disposal and recycling inlormation. 

Bottom Discharge IBC (e.g. - Schuetz Caged IBC or Snyder Square Stackable) 

Pressure rinsing the container before final disposal is the responsibility of the person 

disposing of the container. Cleaning before refilling is the responsibility of the refiller. 

To pressure rinse the container before final disposal, empty the remaining contents 

from the IBC into application equipment or mix tank. Raise the, bottom of the IBC by 

1.5 inches on the side which is opposite of the bottom discharge varve to promote 

more complete product removal. Completely remove the top lid of the IBC. Use water 

pressurized to at least 40 PSI to rinse all Interior portions. Continuously pump or drain 

rinsate into application equipment or rinsate collection system while pressure rinsing. 

Continue pressure rinsing for 2 minutes or until rinsate becomes clear. Replace the lid 

and close bottom valve. 

TOp Discharge IBC, Drums, Kegs (e.g.- Snyder 120 Next Gen, Bonar 8120, Drums, 

Kegs). 

Triple rinsing the container before final disposal is the responsibility of the person 

disposing of the container. Cleaning before refiRing is·the responsibility of the refiller. 

To triple rinse the containers before final disposal, empty the remaining contents from 

this container into application equipment or mix tank. Fill the container at least to 

percent full with water. Agitate vigorously or recirculate water with the pump for 2 

minutes. Rinse all interior surfaces. Pour or pump rinsate into application equipment 

or rinsate collection system. Repeat this procedure two more times. 

Once container is rinsed, offer for recycling if available or puncture and dispose of in a 

sanitary landfill or by inCineration. 

Text to Add to Directions for Use on Labels of Non-Seed Treatment Products In 

Refillable Containers 

End users are authorized to remove tamper evident cables as required to remove the 

product from the container unless the container is equipped with one way valves and 

refilling or returning is planned. If this is the case, end users are not authorized to 

remove tamper evident cables, one way valves or, clean container. See Container 

Disposal instructions under Storage and Disposal. 
Attachment 2 

~Page1 of3~ 

Differences between statements provided in 40 CFR part 156 and 

PR Notice 2007~4, and BeS statements accepted by EPA as of November 2009 

1) Identification of Container Types 

The federal regulations in §t56. t40(c) allow EPA to modify or waive the 

requirements, or permit or require alternative labeling statements, for the 

"Identification of container types" statements that include recycling or reconditioning 

statements. 

BCS uses a statement other than the standard recycling or reconditioning 

statements provided in §156. t40(a)(3) for nonrefillable containers for seed treatment 

products. BCS's instructions for seed treatment products in nonrefillable containers 

direct the user to return the container to BCS or offer it for recycling, dispose of in a 

sanitary landfill, or by incineration. 

2) Pressurewrlnsing instructions for nonrefillable containers that are Bottom 

Discharge IBCs 

The BCS pressure-rinsing instructions are the same for seed and non-seed 

treatment products in rigid, nonrefillable Bottom Discharge IBCs containers that are 

too large to shake. 

8CS adds the statements for the "timing of the residue removal procedure" 

provided in §156.156 for refillable containers to the instructions for nonrefillable 

containers "before final disposaL" Those statements are: "Pressure rinsing the 

container before final disposal is the responsibility of the person disposing of the 

container." The federal regulations in §156.t46(a) give options for instructions to 

clean/rinse nonrefillable containers promptly after emptying, rather than before final 

disposal. 

8CS may use pressure rinsing instructions for nonrefillable bottom discharge 

IBCs, rather than the triple rinsing instructions in §156.146(b). 

In addition, the BCS pressure rinsing instructions differ in the following ways from 

the options for instructions provided in §156. t46(c) for nonrefillable, rigid containers 

of dilutable pesticides that are too large to shake: 

Instead of holding the container upside down over application equipment or 

mix tank, users are instructed to "Raise the bottom of the IBC by 1.5 Inches on the 

side which is opposite of the bottom discharge valve to promote more complete 

product removaL" and to "Completely remove the top lid of the IBC." 

In the language provided in the EPA regulations, users are directed to rinse 

at about 40 PSI for at least 30 seconds and drain for to seconds after the flow 

begins to drip. Instead, the BGS language directs users to continuously pump or 

drain rinsate and to pressure rinse for 2 minutes until rinsate becomes clear. 

Because the BCS language instructs users to completely remove the top lid, 

the label also directs users to replace the lid and close the bottom valve. 

62

Attachment 2 

~Page1 of3~ 

Differences between statements provided in 40 CFR part 156 and 

PR Notice 2007~4, and BeS statements accepted by EPA as of November 2009 

1) Identification of Container Types 

The federal regulations in §t56. t40(c) allow EPA to modify or waive the 

requirements, or permit or require alternative labeling statements, for the 

"Identification of container types" statements that include recycling or reconditioning 

statements. 

BCS uses a statement other than the standard recycling or reconditioning 

statements provided in §156. t40(a)(3) for nonrefillable containers for seed treatment 

products. BCS's instructions for seed treatment products in nonrefillable containers 

direct the user to return the container to BCS or offer it for recycling, dispose of in a 

sanitary landfill, or by incineration. 

2) Pressurewrlnsing instructions for nonrefillable containers that are Bottom 

Discharge IBCs 

The BCS pressure-rinsing instructions are the same for seed and non-seed 

treatment products in rigid, nonrefillable Bottom Discharge IBCs containers that are 

too large to shake. 

8CS adds the statements for the "timing of the residue removal procedure" 

provided in §156.156 for refillable containers to the instructions for nonrefillable 

containers "before final disposaL" Those statements are: "Pressure rinsing the 

container before final disposal is the responsibility of the person disposing of the 

container." The federal regulations in §156.t46(a) give options for instructions to 

clean/rinse nonrefillable containers promptly after emptying, rather than before final 

may use pressure rinsing instructions for nonrefillable bottom discharge 

IBCs, rather than the triple rinsing instructions in §156.146(b). 

In addition, the BCS pressure rinsing instructions differ in the following ways from 

the options for instructions provided in §156. t46(c) for nonrefillable, rigid containers 

of dilutable pesticides that are too large to shake: 

Instead of holding the container upside down over application equipment or 

mix tank, users are instructed to "Raise the bottom of the IBC by 1.5 Inches on the 

side which is opposite of the bottom discharge valve to promote more complete 

product removaL" and to "Completely remove the top lid of the IBC." 

In the language provided in the EPA regulations, users are directed to rinse 

at about 40 PSI for at least 30 seconds and drain for to seconds after the flow 

begins to drip. Instead, the BGS language directs users to continuously pump or 

drain rinsate and to pressure rinse for 2 minutes until rinsate becomes clear. 

Because the BCS language instructs users to completely remove the top lid, 

the label also directs users to replace the lid and close the bottom valve. 
Attachment 2 

.Pago2of3· 

Differences between statements provided In 40 CFR part 156 and 

PR Notice 2007-4, and SCS statements accepted by EPA as of November 2009 

(Note: The federal regulations in 156.146(c) have different pressurewrinse 

Instructions for nonrefillable containers of liquid and solid dilutable pesticides. 

BGS does not indicate whether its instructions would apply to liquid or solid 

dllutables, or both, although these containers are generally designed to hold 

liquids. It is acceptable for BGS to use the same pressure rinsing instructions 

for containers of both liquid and solid dilutable pesticides.) 

3) Triple-rinsing Instructions for Nonrefillable Containers that are Top 

Discharge ISCs, Drums and Kegs 

The BCS triple-rinsing instructions are the same for both seed and nonwseed 

treatment products in rigid, nonrefillable containers that are Top Discharge IBCs, 

Drums, and Kegs. Here is how those instructions differ from the options for 

instructions provided in §156.146(b)(3) for dilutable pesticides in nonrefillable, rigid 

containers too large to shake: 

BCS adds the follOwing statement for the "timing of the residue removal 

procedure" to the triplewrinsing instrUctions for nonrefillable containers: "Pressure 

rinsing [or Cleaning] the container before final disposal is the responsibility of the 

person disposing of the container." The federal regulations, on the other hand, give 

options for instructions to clean/rinse nonrefillable containers promptly after emptying 

[in §156, 146(a)], but not before final disposal. 

Instead of filling the container 'WI full with water, recap and shake for 10 

seconds as provided in the federal regulations under §156.146(b), BCS instructs the 

user to fill the container at least 10% full with water. 

The BCS instructions do not include the sentence for nonrefillable 

containers too large to shake from § 156.146(b)(2)(3) "Replace and tighten closures," 

BCS uses the cleaning instructions from §156, 156(b)(2)(iii) for refillable 

containers for the nonrefillable top discharge IBGs, drums and kegs with the addition 

of the statement "Rinse all interior surfaces". 

The BGS instructions to "Pour or pump rinsate into application equipment 

or rinsate collection system" differs slightly from the language in the regulations 

under §156.146(b), which says "Pour rlnsate into appfication equipment or a mix tank 

or store rinsate for later use or disposal. n 

4) Rinsing Instructions - Refillable Containers 

The BCS pressurewrlnsing instructions (for both seed and non-seed treatment 

products) for refillable Bottom Discharge IBCs are the same as the instructions used 

for nonrefillable bottom discharge IBCs, except that the instructions for refillable 

containers adds: "Cleaning before refilling is the responsibility of the refiller." 

[Required in §156.156(a)]. 

As discussed in section 3 above, the cleaning instructions for the top discharge 

IBCs, drums and kegs are the same as the cleaning instructions from 

63

Attachment 2 

.Pago2of3· 

Differences between statements provided In 40 CFR part 156 and 

PR Notice 2007-4, and SCS statements accepted by EPA as of November 2009 

(Note: The federal regulations in 156.146(c) have different pressurewrinse 

Instructions for nonrefillable containers of liquid and solid dilutable pesticides. 

BGS does not indicate whether its instructions would apply to liquid or solid 

dllutables, or both, although these containers are generally designed to hold 

liquids. It is acceptable for BGS to use the same pressure rinsing instructions 

for containers of both liquid and solid dilutable pesticides.) 

3) Triple-rinsing Instructions for Nonrefillable Containers that are Top 

Discharge ISCs, Drums and Kegs 

The BCS triple-rinsing instructions are the same for both seed and nonwseed 

treatment products in rigid, nonrefillable containers that are Top Discharge IBCs, 

Drums, and Kegs. Here is how those instructions differ from the options for 

instructions provided in §156.146(b)(3) for dilutable pesticides in nonrefillable, rigid 

containers too large to shake: 

BCS adds the follOwing statement for the "timing of the residue removal 

procedure" to the triplewrinsing instrUctions for nonrefillable containers: "Pressure 

rinsing [or Cleaning] the container before final disposal is the responsibility of the 

person disposing of the container." The federal regulations, on the other hand, give 

options for instructions to clean/rinse nonrefillable containers promptly after emptying 

[in §156, 146(a)], but not before final disposal. 

Instead of filling the container 'WI full with water, recap and shake for 10 

seconds as provided in the federal regulations under §156.146(b), BCS instructs the 

user to fill the container at least 10% full with water. 

The BCS instructions do not include the sentence for nonrefillable 

containers too large to shake from § 156.146(b)(2)(3) "Replace and tighten closures," 

BCS uses the cleaning instructions from §156, 156(b)(2)(iii) for refillable 

containers for the nonrefillable top discharge IBGs, drums and kegs with the addition 

of the statement "Rinse all interior surfaces". 

The BGS instructions to "Pour or pump rinsate into application equipment 

or rinsate collection system" differs slightly from the language in the regulations 

under §156.146(b), which says "Pour rlnsate into appfication equipment or a mix tank 

or store rinsate for later use or disposal. n 

4) Rinsing Instructions - Refillable Containers 

The BCS pressurewrlnsing instructions (for both seed and non-seed treatment 

products) for refillable Bottom Discharge IBCs are the same as the instructions used 

for nonrefillable bottom discharge IBCs, except that the instructions for refillable 

containers adds: "Cleaning before refilling is the responsibility of the refiller." 

[Required in §156.156(a)]. 

As discussed in section 3 above, the cleaning instructions for the top discharge 

IBCs, drums and kegs are the same as the cleaning instructions from 
Attachment 2 

~Page3013-

Differences between statements provided in 40 CFR part 156 and 

PR Notice 2007-4, and BCS statements accepted by EPA as of November 2009 

§156, 156(b)(2)(Jii) with the addition of the statement "Rinse all interIor surfaces" and 

a change in the Introduction from "To clean the container before final disposal .. ," to 

"To triple rinse the container before final disposal." 

5) Other Changes to the Container Handling Instructions 

The BCS instructions for disposal of refillable containers for non-seed treatment 

products give users the option of contacting an agricultural retailer or BGS for 

container return, disposal and recycling information; in contrast, the instructions for 

disposal of refillable containers for seed treatment products instruct the user to 

contact BCS Customer Service Center. 

Although not required in §156,140(b), BCS adds a recycling or reconditioning 

statement for refillable containers, 

I n all cases, BCS uses the statement "Once container is rinsed, offer for recycflng 

if available or puncture and dispose of in a sanitary landfill or by incinerations" for 

both nonrefillable and refillable containers of both seed and non-seed treatment 

products. BCS is voluntarily deleting all references to burning as suggested by EPA. 

6) Directions for Use 

Lastly, BGS adds text to the directions for use on the labels of seed and nonseed treatment products in refillable containers that allow the user to remove tamper 

evident cables unless the container has one-way valves arid will be refilled or 

returned, 

64

Attachment 2 

~Page3013-

Differences between statements provided in 40 CFR part 156 and 

PR Notice 2007-4, and BCS statements accepted by EPA as of November 2009 

§156, 156(b)(2)(Jii) with the addition of the statement "Rinse all interIor surfaces" and 

a change in the Introduction from "To clean the container before final disposal .. ," to 

"To triple rinse the container before final disposal." 

5) Other Changes to the Container Handling Instructions 

The BCS instructions for disposal of refillable containers for non-seed treatment 

products give users the option of contacting an agricultural retailer or BGS for 

container return, disposal and recycling information; in contrast, the instructions for 

disposal of refillable containers for seed treatment products instruct the user to 

contact BCS Customer Service Center. 

Although not required in §156,140(b), BCS adds a recycling or reconditioning 

statement for refillable containers, 

I n all cases, BCS uses the statement "Once container is rinsed, offer for recycflng 

if available or puncture and dispose of in a sanitary landfill or by incinerations" for 

both nonrefillable and refillable containers of both seed and non-seed treatment 

products. BCS is voluntarily deleting all references to burning as suggested by EPA. 

6) Directions for Use 

Lastly, BGS adds text to the directions for use on the labels of seed and nonseed treatment products in refillable containers that allow the user to remove tamper 

evident cables unless the container has one-way valves arid will be refilled or 

returned, 
&EPA 

\JNfMa,.. .. 

Environmtnt.1 Pro\aclion Agency (In.. IIf "'1101". 1"'1"'II"nU 1'1100609 

w .. ~ DC 2l>4&Oc 

Notice of flupp1amenull DJetrlbutlon 'Of • Rogllter.d P.atleldt Product 

tnnrucUlJru 

Aftol' 111 regllluant lUa 4)btJlln.!I fin .. rcolstt'ltidn f.:.r tM bllic: prodllet. 1M nt~Ulmt m • ., then aupplllmunatty 

dtslrlbute hl.altwc pl'(Ithlet. On, t':'rrTi mu.t ". &ubmltlld fer IN<:h diITrlbutor produet Md MUll b, signed by thl 

dislI'lbutcr Invc] .... d. Tn. b"ic: fagilltatlon hUmber and tIwI dlatributo. complnV number mm.! b, .hDwn. 

II. rtgll'tWIt "' •• pelland_' dletrfbutor who do .. not hIVI' company number .. lIIiOntd. theRt. .hould have the 

diltltlu!ot appiV . .:." flmmCII:d etatlcnety, to thlt Riclmation DM,iotl 10 han. numbar ... lan~ prior 10 'ubrnltclno 

\hi, I"",,, to 1M -Ottley. 

Thi, Notice of Sup:pfam11'l1ll1 OiSlritmoon Mull b~ aubmm.d by rho t)uic: tlIIDit.lr.anl. TI\I completed form mull haw 

th. conc ..... r&rll:» and IID"lur. of bat;I) the IllgIMr,nt.-.d the dialribu1Dr. 

Royller..cJark,.lnc. 

009 Wa1arslde Drtv. 

St.t!e 800 

NorfoII:, VA 23610 

I--------=:-.===-;=-,;;-:;:c--------------- R&HI AN CondhlfNll s.IMI 81."".,. 

"", , 

I. Thlt dLUributor product tTMJ,ll1;av.lh. um. C:OtnFbli.ion .. the buic: prbcwc;l. : :: 

2. Th. dl:UrlbuwT prodllCt muSI be mllnt,Jf.llIured .rld pllC1c-ood by Ih. sam ....... on \MIO mlHlut'ctullt'.'llI F"'C!atU"'$ 

Iht roghi~ed b .. lo ;mJdllCt. • • ! ' > : 

3. 1M l'b&lin{l to( the di.tributor 1Jlcduct mllft bl" 1hI UtN c1.I/nII ;., mit "nlc 1Jrodut.I, provkl,d. how~.1) th;)l 

spume: cr.lm$. mav b. dII'-,,"d If by dIIlhp.o. no otll" ohtrlilUlo t~ lab.., .r. nlC:NllfY. ' • 

4. T~ prodllCt tI'IU" IIl,",in in tho nunufKll,lr"'l. unbrca.n con"ln,r. ; , ~ , , , 

5. T~ IJbcl mull "lIIlr the EPA raglstrallon numbel 4)\ the ooslo product, klllowlld bv II hyptutn .nd thl &st!i?~t,0!'6 

complny no.mw. 

6. OistributOr prOduCl tihm I'Mllt bl., Ihl name I(Id addt .. ,.:.1 T~ dbUibulOr qudfl.d by lUc:h 'Irm. MI "peckod 

for ... • .. dkltrli>u1od by".': or 'sold by •• ," to) .now ttl-.lttlo nWIII i& Mt 1M! of rtI. manl,>f,llctur,r. 

1. All c.:.ndhl01\t of In. b .. 1c fl011U.t10ft IPflIy lqullly to) dlatlibLJIor producla. It II ttl. rupanalblDty I,)f the balk: 

... giltrant tl,)". tllit ,II cietrib(ltnr ~.bt:ling i, ~t in eomp1~nc. with taQuk'l!m.n\£ pl2c.d on tho buic produtt. 

Dittrfbl.llOr 

w. kH_ ht ~H .... ,~ lind" 110. rx. ..... ,,_ ru_. No ..... pINli..,.,..... ~0Jbj."'I' ht ... _...,,/io,or. ¥u _ _ rloU """"~ .. 

, .. Apdl 24. 2006 

",,,,hil,."t 

r_ Mlr 11>. 1IfII",e,,1Ot _1I.bo". mry"'.o.tr/ltoohtW _lilt /JI-.~ ,.,.....,~~'"'II'~ ...... ~'rl ft> HI. oN'I.wUU lPf#fIH<M rN$ 

~:._. __ ..... ~T~~lf~·?'~01. AJ~ DanielleA.Larochelle o.-t. 3...k11:. __ LL -, &iLl!... Re.g~s!~~~~~~.~.oduct Manager April ~"h 2006 

\ 

I 

> ", 

. 

. ,. , > > ., , 

, 

, , , ... 

, , .. > > •• 

• 

65

&EPA 

\JNfMa,.. .. 

Environmtnt.1 Pro\aclion Agency (In.. IIf "'1101". 1"'1"'II"nU 1'1100609 

w .. ~ DC 2l>4&Oc 

Notice of flupp1amenull DJetrlbutlon 'Of • Rogllter.d P.atleldt Product 

tnnrucUlJru 

Aftol' 111 regllluant lUa 4)btJlln.!I fin .. rcolstt'ltidn f.:.r tM bllic: prodllet. 1M nt~Ulmt m • ., then aupplllmunatty 

dtslrlbute hl.altwc pl'(Ithlet. On, t':'rrTi mu.t ". &ubmltlld fer IN<:h diITrlbutor produet Md MUll b, signed by thl 

dislI'lbutcr Invc] .... d. Tn. b"ic: fagilltatlon hUmber and tIwI dlatributo. complnV number mm.! b, .hDwn. 

II. rtgll'tWIt "' •• pelland_' dletrfbutor who do .. not hIVI' company number .. lIIiOntd. theRt. .hould have the 

diltltlu!ot appiV . .:." flmmCII:d etatlcnety, to thlt Riclmation DM,iotl 10 han. numbar ... lan~ prior 10 'ubrnltclno 

\hi, I"",,, to 1M -Ottley. 

Thi, Notice of Sup:pfam11'l1ll1 OiSlritmoon Mull b~ aubmm.d by rho t)uic: tlIIDit.lr.anl. TI\I completed form mull haw 

th. conc ..... r&rll:» and IID"lur. of bat;I) the IllgIMr,nt.-.d the dialribu1Dr. 

Royller..cJark,.lnc. 

009 Wa1arslde Drtv. 

St.t!e 800 

NorfoII:, VA 23610 

1--------,;;:::;-:;====:::--------------- R&HI AN CondhlfNll s.IMI 81."".,. 

"", , 

I. Thlt dLUributor product tTMJ,ll1;av.lh. um. C:OtnFbli.ion .. the buic: prbcwc;l. : :: 

2. Th. dl:UrlbuwT prodllCt muSI be mllnt,Jf.llIured .rld pllC1c-ood by Ih. sam ....... on \MIO mlHlut'ctullt'.'llI F"'C!atU"'$ 

Iht roghi~ed b .. lo ;mJdllCt. • • ! ' > : 

3. 1M l'b&lin{l to( the di.tributor 1Jlcduct mllft bl" 1hI UtN c1.I/nII ;., mit "nlc 1Jrodut.I, provkl,d. how~.1) th;)l 

spume: cr.lm$. mav b. dII'-,,"d If by dIIlhp.o. no otll" ohtrlilUlo t~ lab.., .r. nlC:NllfY. ' • 

4. T~ prodllCt tI'IU" IIl,",in in tho nunufKll,lr"'l. unbrca.n con"ln,r. ; , ~ , , , 

5. T~ IJbcl mull "lIIlr the EPA raglstrallon numbel 4)\ the ooslo product, klllowlld bv II hyptutn .nd thl &st!i?~t,0!'6 

complny no.mw. 

6. OistributOr prOduCl tihm I'Mllt bl., Ihl name I(Id addt .. ,.:.1 T~ dbUibulOr qudfl.d by lUc:h 'Irm. MI "peckod 

for ... • .. dkltrli>u1od by".': or 'sold by •• ," to) .now ttl-.lttlo nWIII i& Mt 1M! of rtI. manl,>f,llctur,r. 

1. All c.:.ndhl01\t of In. b .. 1c fl011U.t10ft IPflIy lqullly to) dlatlibLJIor producla. It II ttl. rupanalblDty I,)f Ihe balk: 

"'giltrar'll 11,)". thll III cietrib(ltnr ~.bt:ling il ~t in eomp1~nc. with I'IQuk'l!mln\£ pl2c.d on 1M buic produtt. 

Dittrfbl.llOr 

w. kH_ ht ~H .... ,~ lind" 110. rx. ..... ,,_ ru_. No ..... pINli..,.,..... ~0Jbj."'I' ht ... _...,,/io,or. ¥u _ _ rloU """"~ .. 

, .. Apdl 24. 2006 

"1",hil,."1 

r_ Mlr 11>. 1IfII",e,,1Ot _1I.bo". mry"'.o.tr/ltoohtW _lilt /JI-.~ ,.,.....,~~'"'III~ ...... ~'rl ft> HI. oN'I.wUU lPf#fIH<M rN$ 

~:._' __ " ..'~T~~lf~·?'~0{. AJ~ DanielleA.Larochelle D.-t. 3...k11:. __ LL -, &iLl!... Re.g~s!~~~~~~.~.oduct Manager April ~"h 2006 

\ 

I 

> ", 

. 

. ,. , > > ., , 

, 

, , , ... 

, , .. 
&EPA 

U,.._Stat .. 

Environmantal Protection Agency ~ f& "'\1A\ \0 Qf'fIc. of Pntlctd. P~r.". (7505C) . t 

Wnh1ngtDn. DC 204«1 

Notice of Supplemental Distribution of a Registered Pesticide Product 

Inmuctlons 

Attar a registrant has obtained final registration for thO basic prOduct. the registrant may then SUPJ)lamentalfy 

diatributa his/her product. Ona form must be submitted for •• ch distributor product and mUl;t be signed by the 

distributor involved, The basic registration number and the distributor company number must be shown. 

If a registrant has a potential distributor who does not have a company number assigned. she/he should have the 

distributor apply, on Jatterhaad stationery. to the Registration Division to nave a number uslgned prior to submitting 

this form to the agency. 

This Notice of Supplemental Distribution must be submitted by the basic regIstrant. The compteted fann must have 

the concurrence and signature of both the registrant and the distributor. 

EPA R'cllstratlon. NurrIb« of Pr.dlJct 

21>4418 

Note: 00 not submit dfstribLitor product label, 

N.m. of R,aIett,.d ProcfuI!I Ib-.k; PI"Odlll:r nam. IICCMNd by EPAI 

PREP brilnd E~phoo ~bkicre 

Teo~~ 

100 North PolntCl!nter "-

Suite 330 

Alpharetta. GA 30022-8142 

T~kw: Ethephon 6 

1. The distributor product must have the same composition as the baaic: prOduct. 

2. The distributor product must be manufactured and packaged by the sama person who manufactures and pac1Qges 

the regi$tered basic product. 

3. The labehng for the distributor product must bear the same claims as the basic product. provided. however. that 

specific claims may be delated If by doing $:0. no otluK changos to the labet are n&ensary. 

4. The product mu$t remain in the manufacturer's unbroken container. 

S. The label must bear the EPA registration number of the basic product. followed by a hyphan and the distributor's 

company number. 

6. Distributor product labels must bear the name and address of the distributor qualified by such terms as ·packed 

for ... ·, "distributed by ... "; or "sold by ..... to show that the name is not that of the manufacrurer. 

7. All conditions of the basic registration apply equally to distributor products. It is the responsibiUtv of the basic 

registrant to see that all distributor labeling is kept In compliance with requirements placed on the basic product. 

Distributor 

, Dat", ' 

(?,'\): ,h, '~,()J () 

EPA Ferm 8570.5 fRev. U04) ~. Millon ••• o~ta. 

>, , , 

66

&EPA 

U,.._Stat .. 

Environmantal Protection Agency ~ f& "'\1A\ \0 Qf'fIc. of Pntlctd. P~r.". (7505C) . t 

Wnh1ngtDn. DC 204«1 

Notice of Supplemental Distribution of a Registered Pesticide Product 

Inmuctlons 

Attar a registrant has obtained final registration for thO basic prOduct. the registrant may then SUPJ)lamentalfy 

diatributa his/her product. Ona form must be submitted for •• ch distributor product and mUl;t be signed by the 

distributor involved, The basic registration number and the distributor company number must be shown. 

If a registrant has a potential distributor who does not have a company number assigned. she/he should have the 

distributor apply, on Jatterhaad stationery. to the Registration Division to nave a number uslgned prior to submitting 

this form to the agency. 

This Notice of Supplemental Distribution must be submitted by the basic regIstrant. The compteted fann must have 

the concurrence and signature of both the registrant and the distributor. 

EPA R'cllstratlon. NurrIb« of Pr.dlJct 

21>4418 

Note: 00 not submit dfstribLitor product label, 

N.m. of R,aIett,.d ProcfuI!I Ib-.k; PI"Odlll:r nam. IICCMNd by EPAI 

PREP brilnd E~phoo ~bkicre 

Teo~~ 

100 North PolntCl!nter "-

Suite 330 

Alpharetta. GA 30022-8142 

T~kw: Ethephon 6 

1. The distributor product must have the same composition as the baaic: prOduct. 

2. The distributor product must be manufactured and packaged by the sama person who manufactures and pac1Qges 

the regi$tered basic product. 

3. The labehng for the distributor product must bear the same claims as the basic product. provided. however. that 

specific claims may be delated If by doing $:0. no otluK changos to the labet are n&ensary. 

4. The product mu$t remain in the manufacturer's unbroken container. 

S. The label must bear the EPA registration number of the basic product. followed by a hyphan and the distributor's 

company number. 

6. Distributor product labels must bear the name and address of the distributor qualified by such terms as ·packed 

for ... ·, "distributed by ... "; or "sold by ..... to show that the name is not that of the manufacrurer. 

7. All conditions of the basic registration apply equally to distributor products. It is the responsibiUtv of the basic 

registrant to see that all distributor labeling is kept In compliance with requirements placed on the basic product. 

Distributor 

, Dat", ' 

(~'O:' Q '~,()J () 

EPA Ferm 8570.5 fRev. U04) ~. Millon ••• o~ta. 

>, , , 
Bayer CropScience 

May 20,2010 

Document Processing Desk (AMEND) 

Office of Pesticide Program (H7504P) 

U.S. EPA, Room S4900 

One Potomac Yard 

Arlington, VA 22202 -4525 

A TIN: Mr. Tony Kish (PM 22) 

Registration Division (7505P) 

Subject: PREP brand Ethephon for Cotton and Tobacco (Reg. No.: 264-418): 

Submission of the Application of Pesticide Notification under PR Notice 2007-4 (Ref.: 

the Pesticide Container and Containment Final Rule, August 16, 2006) 

Dear Mr. Kish: 

Bayer CropScience herein submits this amendment for the PREP brand Ethephon for 

Cotton and Tobacco (Reg. No.: 264-418), a solution containing ethephon as the active 

ingredient. The amendment is to comply with the label language required by the regulation 

in 40 CFR part r5b"eSfiiIiITShed by the Final Rule "Pesticide Management and Disposal; 

Standards for Pesticide Container and Containment" (August 16, 2006). Based on the 

Guidance issued under the PR Notice 2007-4 and the product-specific information, we 

propose the following "Container Disposal" labeling (see Section for "Storage and 

Disposal"): , . , ~ 

, , , , 

CONTAINER DISPOSAL 

Rigid, Non-refi11able containers small enough to shake (i.e., with capacities equal to or less thaJl~5,~0I}19ns) 

, ,. 

, , , . , , " , 

Non·refillable container. Do not reuse or refill this container. Offer fOr recycling, if available. Triple rins~ or prdsure ri~se~ • > , 

container (or equivalent) promptly after emptying. Triple rinse as follows: Empty the remaining contents'irM aoplicatiori' • > • 

equipment or a mix tank and drain for 10 seconds after the flow begins to drip. Fill the container 1/4 full wit;', water an,'j' , 

recap. Shake for 10 seconds. Pour rjnsate into application equipment or a mix tank or store rinsate for,I:1It£l~ ,1se or di~pobb ' 

Drain for 10 seconds after the flow begins to drip. Repeat this procedure two more times. Once contaiO;lf~r;il ~irlsed, offer fQr 

recycling if available or puncture and dispose of in a sanitary landfill. , " ., , , , 

, , , , 

," , 

67

Bayer CropScience 

May 20,2010 

Document Processing Desk (AMEND) 

Office of Pesticide Program (H7504P) 

U.S. EPA, Room S4900 

One Potomac Yard 

Arlington, VA 22202 -4525 

A TIN: Mr. Tony Kish (PM 22) 

Registration Division (7505P) 

Subject: PREP brand Ethephon for Cotton and Tobacco (Reg. No.: 264-418): 

Submission of the Application of Pesticide Notification under PR Notice 2007-4 (Ref.: 

the Pesticide Container and Containment Final Rule, August 16, 2006) 

Dear Mr. Kish: 

Bayer CropScience herein submits this amendment for the PREP brand Ethephon for 

Cotton and Tobacco (Reg. No.: 264-418), a solution containing ethephon as the active 

ingredient. The amendment is to comply with the label language required by the regulation 

in 40 CFR part r5b"eSfiiIiITShed by the Final Rule "Pesticide Management and Disposal; 

Standards for Pesticide Container and Containment" (August 16, 2006). Based on the 

Guidance issued under the PR Notice 2007-4 and the product-specific information, we 

propose the following "Container Disposal" labeling (see Section for "Storage and 

Disposal"): , . , ~ 

, , , , 

CONTAINER DISPOSAL 

Rigid, Non-refi11able containers small enough to shake (i.e., with capacities equal to or less thaJl~5,~0I}19ns) 

, ,. 

, , , . , , " , 

Non·refillable container. Do not reuse or refill this container. Offer fOr recycling, if available. Triple rins~ or prdsure ri~se~ • > , 

container (or equivalent) promptly after emptying. Triple rinse as follows: Empty the remaining contents'irM aoplicatiori' • > • 

equipment or a mix tank and drain for 10 seconds after the flow begins to drip. Fill the container 1/4 full wit;', water an,'j' , 

recap. Shake for 10 seconds. Pour rjnsate into application equipment or a mix tank or store rinsate for,I:1It£l~ ,1se or di~pobb ' 

Drain for 10 seconds after the flow begins to drip. Repeat this procedure two more times. Once contaiO;lf~r;il ~irlsed, offer fQr 

recycling if available or puncture and dispose of in a sanitary landfill. , " ., , , , 

, , , , 

," , 
Rigid Non-refillable containers that are too large to shake (i.e.) with capacities greater than 5 gallons or 50 lbs) 

Non-refillable Containers 

Non-refillable containers - Do not reuse or refill this container. Refer to Bottom Discharge IBC or Top Discharge IBC, Drums, 

Kegs infonnation as follows. 

Bottom Discharge IBC (e.g. - Schuetz Caged IBC or Snyder Square Stackable) 

Pressure rinsing the container before final disposal is the responsibility of the person disposing of the container. To pressure 

rinse the container before final disposal, empty the remaining contents from the IBC into application equipment or mix tank. 

Raise the bottom of the IBC by 1.5 inches on the side which is opposite of the bottom discharge valve to promote more 

complete product removal. Completely remove the top lid of the lBC. Use water pressurized to at least 40 PSI to rinse all 

interior portions. Continuously pump or drain rinsate into application equipment or rinsate collection system while pressure 

rinSing. Continue pressure rinsing for 2 minutes or until rinsate becomes clear. Replace the lid and close bottom valve. 

Top Discharge IBC, Drums, Kegs (e.g.- Snyder 120 Next Gen, Bonar B120, Drums, Kegs). 

Triple rinsing the container before final disposal is the responsibility of the person disposing of the container. To triple rinse 

the container before final disposal, empty the remaining contents from this container into application equipment or mix tank. 

Fill the container at least 10 percent full with water. Agitate vigorously or recirculate water with the pump for 2 minutes. 

Rinse all interior surfaces. Pour or pump rinsate into application equipment or rinsate collection system. Repeat this 

procedure two more times. Once container is rinsed, offer for recycling if available or puncture and dispose of in a sanitary 

landfill. 

Refillable Containers 

Refillable container - Refer to Bottom Discharge IBC or Top Discharge IBC, Drums, Kegs infonnation as follows. Refill this 

container with pesticide only. Do not reuse this container for any other purpose. After emptying product from container,either 

return container to Bayer CropScience per instructions from Bayer CropScience Customer Service Center (f-800-527-4781) 

or rinse and either recycle or dispose of the container as follows: 

Bottom Discharge IBC (e.g. - Schuetz Caged IBC or Snyder Square StackabJe) 

Pressure rinsing the container before final disposal is the responsibility of the person disposing of the container. Cleaning 

before refilling is the responsibility of the refiller. To pressure rinse the container before final disposal, empty the remaining 

contents from the IBC into application equipment or mix tank. Raise the bottom of the IBC by 1.5 inches on the side which is 

opposite of the bottom discharge valve to promote more complete product removal. Completely remove the top lid of the 

IBC. Use water pressurized to at least 40 PSI to rinse all interior portions. Continuously pump or drain rinsate into 

application equipment or rinsate collection system while pressure rinsing. Continue pressure rinsing for 2 minutes or until 

rinsate becomes clear. Replace the lid and close bottom valve. 

Top Discharge lBC, Drums, Kegs (e.g.- Snyder 120 Next Gen, Bonar B120, Drums, Kegs)_ 

Triple rinsing the container before final disposal is the responsibility of the person disposing of the container. Cleaning 

before refilling is the responsibility of the refiller. To triple rinse the containers before final disposal, empty the remaining 

contents from this container into application equipment or mix tank. Fill the container at least 10 percent full with water. 

Agitate vigorously or recirculate water with the pump for 2 minutes. Rinse all interior surfaces. Pour or pump rinsate into 

application equipment or rinsate collection system. Repeat this procedure two more times. Once container is rinsed, offer for 

recycling if available or puncture and dispose of in a sanitary landfill. 

Refillable Containers 

End users are authorized to remove tamper evident cables as required to remove the product from the container unleS$JI}E" 

container is equipped with one way valves and refilling or returning is planned. If this is the case, end users are not ~.,.,' 

aulhorized to remove tamper evident cables, one way valves or clean container. See Container Disposal instructions under 

Storage and Disposal. ••• , ~ 

) .... Enclosed is an EPA Fonn 8570-1, one copy ofthe revised PREP brand Ethephon f01-COttol-l' >' • , , and Tobacco (Reg. No.: 264-418) label for review, and an extra page (with the Cohtainer ,. 

Disposal Section) where the revised/new text is highlighted. . " , ;" , , ;, , ) 

" 

This amendment is consistent with the guidance in PR Notice 2007-4 and EPA's :'" » 

alternative language acceptance letter to Bayer CropScience dated November 10, 2009. No otpe, , > <-

changes have been made to the labeling or the Confidential Statement of Formula for this prodat(.' 

I understand that it is a violation of 18 U.S.c. Section 1001 to willfully make any false statement to 

68

2 

Rigid Non-refillable containers that are too large to shake (i.e.) with capacities greater than 5 gallons or 50 lbs) 

Non-refillable Containers 

Non-refillable containers - Do not reuse or refill this container. Refer to Bottom Discharge IBC or Top Discharge IBC, Drums, 

Kegs infonnation as follows. 

Bottom Discharge IBC (e.g. - Schuetz Caged IBC or Snyder Square Stackable) 

Pressure rinsing the container before final disposal is the responsibility of the person disposing of the container. To pressure 

rinse the container before final disposal, empty the remaining contents from the IBC into application equipment or mix tank. 

Raise the bottom of the IBC by 1.5 inches on the side which is opposite of the bottom discharge valve to promote more 

complete product removal. Completely remove the top lid of the lBC. Use water pressurized to at least 40 PSI to rinse all 

interior portions. Continuously pump or drain rinsate into application equipment or rinsate collection system while pressure 

rinSing. Continue pressure rinsing for 2 minutes or until rinsate becomes clear. Replace the lid and close bottom valve. 

Top Discharge IBC, Drums, Kegs (e.g.- Snyder 120 Next Gen, Bonar B120, Drums, Kegs). 

Triple rinsing the container before final disposal is the responsibility of the person disposing of the container. To triple rinse 

the container before final disposal, empty the remaining contents from this container into application equipment or mix tank. 

Fill the container at least 10 percent full with water. Agitate vigorously or recirculate water with the pump for 2 minutes. 

Rinse all interior surfaces. Pour or pump rinsate into application equipment or rinsate collection system. Repeat this 

procedure two more times. Once container is rinsed, offer for recycling if available or puncture and dispose of in a sanitary 

landfill. 

Refillable Containers 

Refillable container - Refer to Bottom Discharge IBC or Top Discharge IBC, Drums, Kegs infonnation as follows. Refill this 

container with pesticide only. Do not reuse this container for any other purpose. After emptying product from container,either 

return container to Bayer CropScience per instructions from Bayer CropScience Customer Service Center (f-800-527-4781) 

or rinse and either recycle or dispose of the container as follows: 

Bottom Discharge IBC (e.g. - Schuetz Caged IBC or Snyder Square StackabJe) 

Pressure rinsing the container before final disposal is the responsibility of the person disposing of the container. Cleaning 

before refilling is the responsibility of the refiller. To pressure rinse the container before final disposal, empty the remaining 

contents from the IBC into application equipment or mix tank. Raise the bottom of the IBC by 1.5 inches on the side which is 

opposite of the bottom discharge valve to promote more complete product removal. Completely remove the top lid of the 

IBC. Use water pressurized to at least 40 PSI to rinse all interior portions. Continuously pump or drain rinsate into 

application equipment or rinsate collection system while pressure rinsing. Continue pressure rinsing for 2 minutes or until 

rinsate becomes clear. Replace the lid and close bottom valve. 

Top Discharge lBC, Drums, Kegs (e.g.- Snyder 120 Next Gen, Bonar B120, Drums, Kegs)_ 

Triple rinsing the container before final disposal is the responsibility of the person disposing of the container. Cleaning 

before refilling is the responsibility of the refiller. To triple rinse the containers before final disposal, empty the remaining 

contents from this container into application equipment or mix tank. Fill the container at least 10 percent full with water. 

Agitate vigorously or recirculate water with the pump for 2 minutes. Rinse all interior surfaces. Pour or pump rinsate into 

application equipment or rinsate collection system. Repeat this procedure two more times. Once container is rinsed, offer for 

recycling if available or puncture and dispose of in a sanitary landfill. 

Refillable Containers 

End users are authorized to remove tamper evident cables as required to remove the product from the container unleS$JI}E" 

container is equipped with one way valves and refilling or returning is planned. If this is the case, end users are not ~.,.,' 

aulhorized to remove tamper evident cables, one way valves or clean container. See Container Disposal instructions under 

Storage and Disposal. ••• , ~ 

) .... Enclosed is an EPA Fonn 8570-1, one copy ofthe revised PREP brand Ethephon f01-COttol-l' >' • , , and Tobacco (Reg. No.: 264-418) label for review, and an extra page (with the Cohtainer ,. 

Disposal Section) where the revised/new text is highlighted. . " , ;" , , ;, , ) 

" 

This amendment is consistent with the guidance in PR Notice 2007-4 and EPA's :'" » 

alternative language acceptance letter to Bayer CropScience dated November 10, 2009. No otpe, , > <-

changes have been made to the labeling or the Confidential Statement of Formula for this prodat(.' 

I understand that it is a violation of 18 U.S.c. Section 1001 to willfully make any false statement to 

2 
EPA. I further understand that if the amended label is not consistent with the requirements of 40 

CFR §§ 156.1 0, 156.l40, 156.144, l56.146 and 156.l56, this product may be in violation of FIFRA 

and 1 may be sUbjected to enforcement action and penalties under Section 12 and 14 of FlFRA". 

Please contact me if you should have further questions. 

Sincerely, 

cYUU1k 

Laura Phelps 

Regulatory Affairs, Herbicides & PGRs 

Bayer CropScience 

2 T. W. Alexander Drive 

RTP, NC 27709 

office: 919-549-2302 

mobil:919-352-8075 

email: laura.phelps@bayercropscience.com 

, , " " , 

, , , > 

, • > , 

, > , , , , 

, > > > 

) , , J ' • ", , • , , " , , , , , ) . , ,,), , 

) , , , 

, > , , 

69

3 

EPA. I further understand that if the amended label is not consistent with the requirements of 40 

CFR §§ 156.1 0, 156.l40, 156.144, l56.146 and 156.l56, this product may be in violation of FIFRA 

and 1 may be sUbjected to enforcement action and penalties under Section 12 and 14 of FlFRA". 

Please contact me if you should have further questions. 

Sincerely, 

cYUU1k 

Laura Phelps 

Regulatory Affairs, Herbicides & PGRs 

Bayer CropScience 

2 T. W. Alexander Drive 

RTP, NC 27709 

office: 919-549-2302 

mobil:919-352-8075 

email: laura.phelps@bayercropscience.com 

, , " " , 

, , , > 

, • > , 

, > , , , , 

, > > > 

) , , J ' • ", , • , , " , , , , , ) . , ,,), , 

) , , , 

, > , , 

3 
PI .... ,..d itJ#trUCtIoM on • b.fON m •• J:=: . Fllrm A2I1:rov!S!. OM! ,,:I'o70-00eo . Unite/Statol ~ Registration OPP Identifier Numbllr 

&EPA Environmental Protection Agency x Amendment 

Waahington. DC 20460 Other 

Application for Pesticide ~ Section I 

1. COmpany/Produet Number 2. EPA Produet MIIneger 3. Propolod Clo .. ifieetion 

264-418 Mr. Tony Kish 

ONone o R .. trieted 

4. CoptanYJProduet (Nemal 

PREP rand Ethephon PM' PM Team # 22 

S. Name and Addre .. of Applicant (Include ZIP Codl' 6. Expedited Review. In accordance with FIFRA Section 3Ic)(3) 

Bayer CropSciencei (bllil. my product is similar or identical in composition and labeling 

P.O. Box 120 14, 2 T.w. Alexander Drive; to: 

Research Trianqle Park, NC 27709 0 EPA Reg. No. 

D Ch.r;k if this is "nllw Iddrll$$ Product Name 

Section - II 

0 Amllndment - EXplain below. 0 Final printlld labelll in respOn8"e to 

Agsnoy Iliner deted 

0 Resubml"lon In fellpOn.s to Agoncy Isnsr datod 0 ·Ms Too· Applioetion. 

0 Nlltillcation • Explain billow. 0 Other· Explain balow. 

Explanation: U.o odditionel pIIgIIIII If necelilary. {For .action I arid Sliction 11.1 

BayerCropScience would like to add the required container disposal language to the PREP brand Ethephon for Cotton and Tobacco 

label per PR Notice 2007-4 

Section - III 

1. Material nu. Product Will Be Pacbgad In: 

Child-ROIistant Paekaging Unit Paekaging Wstar Soluble Peckaging 2. Type of Container 

f~t· ~V" fa V" 

X N. X N. §M". X Plelltio 

N. Glall. 

• Certification must If ~Y8'· No. par If ·VIIS· No. per Papsr 

Unit Paekeging wgt. containar Paekltgll wgt container Othllr (Spllclfy! b. submitted 

I 

3. Loeation of Net Content. Information 4. Sizals) Retail Contalnar 5. Locetion of Label Directionll 

I8l o Containar 2.S;9.S;30;220g ~ On Labal 

Label On Labliling accompenying product 

6. Monnar in Which labal is Affixacl to P,oouet E Uthogreph 0 Other 

Pap.r reuOd 

Stonci ad 

Section - IV 

1. Conlact Point (Compr.ra irflfrlS dir.ctly billow for idtHltification ofindividueJ ro b. conracrtld, if nacauary, to proca$$ this lIppJir:fJti:J,~.J 

. ~ .. Nama TItia Tataphone No. (lncludll Araa Coda) 

Laura Phelps Reg. Affairs Specialist ~ ... , , , ., , 

Certification ' , , .t ,. 6. Deta 'Applicatilln , , 

I eartity that tha statamonts I havo mllde on this form and all anaehments therato ara tllJa, accurata and eofupleta. , R!.lc.~Md , , Ilicknowladge thet any knowingly fohla or mislaading statement may be punishable by finll or ImpriIlOf"lmllnt'o'r; .t • , ',Stamped' both undltl appneoblelaw. " " , , , , , " j J , , " 22% flu ~ 3. TItla , > , > , • , 

'", CrAMec '1t J- Reg. Affairs Specialist , , , > > • , > 

, 

4. Typed Nama 5.0ela .t , > > , , 

Laura Phelps > , , , 

20May2010 

, , Whh •• EPA Fu. Copy lorigln~1 V.llow • Applicant Capy 

70

PI .... ,..d itJ#trUCtIoM on • b.fON mltl.ti ):aa: . Fllrm A2I1:rov!S!. OM! \2070-00eo . Unitll/Statol ~ Registration OPP Idllntifillr Numbllr 

&EPA Environmental Protection Agency x Amendment 

Waahington. DC 20460 Other 

Application for Pesticide ~ Section I 

1. COmpany/Produet Number 2. EPA Produet Manager 3. Propolod Clo .. ifieation 

264-418 Mr. Tony Kish o Nonll o R .. trieted 

4. CoptanYJProduet (Nemal 

PREP rand Ethephon PM' PM Team # 22 

S. Name and Addre .. of Applicant (Include ZIP Codl' 6. Expedited Review. In accordance with FIFRA Section 3Ic)(3) 

Bayer CropSciencei (bllil. my product is similar or identical in composition and labeling 

P.O. Box 120 14, 2 T.w. Alexander Drive; to: 

Research Trianqle Park, NC 27709 0 EPA Reg. No. 

D Ch.r;k if this is "nllw Iddrll$$ Product Name 

Section - II 

0 Amllndmllnt - EXplain below. 0 Final printlld labelll in respOn8"e to 

Agsnoy IlInlir dlltlld 

0 Resubml"lon In flillpOn.S to Agoncy Isnsr datod 0 ·Ms Too· Appliolltion. 

0 Nlltillcation • Explain balow. 0 Other· Explain balow. 

Explanation: U.o odditionel pIIgIIIII If neclllliary. {For .action I arid Sliction 11.1 

BayerCropScience would like to add the required container disposal language to the PREP brand Ethephon for Cotton and Tobacco 

label per PR Notice 2007-4 

Section - III 

1. Material nu. Product Will Be Pacbgad In: 

Child-ROIistant Paekaging Unit Paekaging Wstar Soluble Peckaging 2. Type of Container 

f~t· ~V" fa V" 

X N. X N. §M". X Plelltio 

N. Glall. 

• Certification must If ~Y8'· No. par If ·VIIS· No. per Papsr 

Unit Paekaging wgt. containar Paekltgll wgt container Othllr (Spllclfy! b. submitted 

I 

3. Loeation of Nllt Content. Information 4. Sizals) Retail Contalnar 5. Loclltion of Label Dirllctionll 

I8l o Containar 2.S;9.S;30;220g ~ On Labal 

Label On Labliling accompenying product 

6. Monnar in Which labal is Affixacl to P,oouet 1C Uthogrllph 

Pap.r reuOd 

Stonci ad 

0 Othllr 

Section - IV 

1. Conlact Point (Compr.ra irflfrlS dir.ctly billow for idtHltification ofindividuaJ ro b. conracrtld, if nacauary, to proca$$ this lIppJir:fJti:J,~.J 

. ~ .. Nama TItia Tataphone No. (lncludll Araa Coda) 

Laura Phelps Reg. Affairs Specialist ~ ... , , , ., , 

Certification ' , , .t ,. 6. Dllta 'Applicatilln , , 

I eartity that tha statamonts I havo mlldll on this form and all anaehments therato ara tllJa, accurata and eofupleta. , R!.lc.~Md , , Ilicknowladgli thet any knowingly fohla or mislaading statement may bll punishable by finll or ImpriIlOf"lmllnt'o'r; .t • , ',Stamped' both undltl appneobllllaw. " " , , , , 

2. Sl'~" // fN ,,/2 ' " j J , , 3. TItla , " > , > , • , 

(7CiAMec VA 0, V ..J Reg. Affairs Specialist , , , > > • , > 

, 

4. Typed Nama 5.01l1a .t , > > , , 

Laura Phelps > , , , 

20May2010 

.. Whh •• EPA Fu. Copy lorigln~1 V.llow • Applicant Capy 
PRE P TM brand Ethephon FOR COTTON AND TOBACCO 

For Commercial Use Or Agricultural Use Only. Not For Residential Use 

ACTIVE INGREDIENT: Ethephon (2-Chloroethyl) phosphonic acid* .......................................................................... 55,4% 

INERT INGREDIENTS: ................................................................................................................................................. 44.6% 

*This product contains 6 pounds ethephon per gallon. 

EPA Reg. No. 264·418 EPA Est. No. 264-PA·01 

KEEP OUT OF REACH OF CHILDREN 

DANGER PELIGRO 

Si usted no entiende la etiqueta, busque a alguien para que se la explique a usted en detalle. 

(If you do not understand the laber, find someone to explain it to you in detail.) 

For MEDICAL And TRANSPORTATION Emergencies ONLY Call 24 Hours A Day 1·800·334·7577 

For PRODUCT USE Information Call1·866-99BAYER (1·866·992-2937) 

The use of this product for a variety of plant growth regulation uses are protected by United Siates and foreign patents including 

U.S. Patent 4,240,819. No license is granted to use this product in countries other than the United States or for any use not 

contemplated by this label. Liability for patent infringement may result from use or sale of this product outside the United States. 

FIRST AID 

IF IN EYES: • Ho!d eye open and rinse slowly and gently with water for 15-20 minutes. 

• Remove contact lenses, if present, after the first 5 minutes, then continue rinsing eye. 

• Call a poison control center or doctor for treatment advIce. 

!F ON SKIN OR • Take off contaminated clothing. 

CLOTH!NG: 

• Rinse skin immediately with plenty of water for 15-20 minutes. 

• Call a Doison control center or doctor for treatment advice. 

IF SWALLOWED: • !mmediately cal! a poison control center or doctor for treatment advice. 

• Do not induce vomiting unless told to do so by a poison control center or doctor. 

• Have person sip a glass of water if able to swallow. 

• Do nolgjve anything !:?ymouth to an unconscious person. 

For MEDICAL Emergencies Call 24 Hours A Day 1·800·334·7577. 

Have the product container or labe! with you when calling a poison control center or doctor or going for treatment. 

NOTE TO PHYSICIAN: Treat symptomatically. Consideration should be given to the possibility that overexposure to materials other 

than this product may have occurred. No speCific antidote is available. Probable mucosal damage may contraindicate the use of 

oastric lavaae 

PRECAUTIONARY STATEMENTS 

DANGER 

HAZARDS TO HUMANS AND DOMESTIC ANIMALS , , , , " , " 

,» 

, 

" ", 

, , 

CORROSIVE. Causes irreversible eye damage and skin bums. 

skin or on clothing. 

Harmfu! if swallowed or absorbed throuyh skin.' 00 nqt"9l:lt m.eyes, on 

""" , "" 

PERSONAL PROTECTIVE EQUIPMENT (PPE) , , 0"", ,. 

Applicators and other handlers must wear coveralls over short·sleeved shirts and short pants. chemict"J Meistant gloves made of any 

waterproof material (such as Nitrile, Butyl. Neoprene and/or Barrier Laminate). chemical-resistant footwear plus ~ocks, protective 

eyewear, chemical-resistant headgear for overhead exposure and chemical-resistant apron when cleaning equipmej1i bt hlixing and 

loading. 

Discard clothing and other absorbent materials that have been drenched or heavily contaminated with this products con'c~n~~I!'e. Do not 

reuse them. Follow manufacturer's instructions for cleaning/maintaining PPE. If no such instructions for washables, use detergent and 

hot water. Keep and wash PPE separately from other laundry. t 

71

PRE P TM brand Ethephon FOR COTTON AND TOBACCO 

For Commercial Use Or Agricultural Use Only. Not For Residential Use 

ACTIVE INGREDIENT: Ethephon (2-Chloroethyl) phosphonic acid* .......................................................................... 55,4% 

INERT INGREDIENTS: ................................................................................................................................................. 44.6% 

*This product contains 6 pounds ethephon per gallon. 

EPA Reg. No. 264·418 EPA Est. No. 264-PA·01 

KEEP OUT OF REACH OF CHILDREN 

DANGER PELIGRO 

Si usted no entiende la etiqueta, busque a alguien para que se la explique a usted en detalle. 

(If you do not understand the laber, find someone to explain it to you in detail.) 

For MEDICAL And TRANSPORTATION Emergencies ONLY Call 24 Hours A Day 1·800·334·7577 

For PRODUCT USE Information Call1·866-99BAYER (1·866·992-2937) 

The use of this product for a variety of plant growth regulation uses are protected by United Siates and foreign patents including 

U.S. Patent 4,240,819. No license is granted to use this product in countries other than the United States or for any use not 

contemplated by this label. Liability for patent infringement may result from use or sale of this product outside the United States. 

FIRST AID 

IF IN EYES: • Ho!d eye open and rinse slowly and gently with water for 15-20 minutes. 

• Remove contact lenses, if present, after the first 5 minutes, then continue rinsing eye. 

• Call c!'p_oison control center or doctor for treatment advIce. 

!F ON SKIN OR • Take off contaminated clothing. 

CLOTH!NG: 

• Rinse skin immediately with plenty of water for 15-20 minutes. 

• Call a Doison control center or doctor for treatment advice. 

IF SWALLOWED: • !mmediately cal! a poison control center or doctor for treatment advice. 

• Do not induce vomiting unless told to do so by a poison control center or doctor. 

• Have person sip a glass of water if able to swallow. 

• Do not aive anvthino bv mouth to an unconscious oerson. 

For MEDICAL Emergencies Call 24 Hours A Day 1·800·334·7577. 

Have the Droduct container or labe! with you when callino a Doison control center or doctor or aoina for treatment. 

NOTE TO PHYSICIAN: Treat symptomatically. Consideration should be given to the possibility that overexposure to materials other 

than this product may have occurred. No speCific antidote is available. Probable mucosal damage may contraindicate the use of 

oastric lavaoe 

PRECAUTIONARY STATEMENTS 

DANGER 

HAZARDS TO HUMANS AND DOMESTIC ANIMALS , , , , " , " 

,» 

, , " ", 

, , 

CORROSIVE. Causes irreversible eye damage and skin bums. 

skin or on clothing. 

Harmfu! if swallowed or absorbed throuyh skin.' 00 nqt"9l:lt m.eyes, on 

""" , "" 

PERSONAL PROTECTIVE EQUIPMENT (PPE) , , 0"", ,. 

Applicators and other handlers must wear coveralls over short·sleeved shirts and short pants. chemict"J Meistant gloves made of any 

waterproof material (such as Nitrile, Butyl. Neoprene and/or Barrier Laminate). chemical-resistant footwear plus ~ocks, protective 

eyewear, chemical-resistant headgear for overhead exposure and chemical-resistant apron when cleaning equipmej1i bt hlixing and 

loading. 

Discard clothing and other absorbent materials that have been drenched or heavily contaminated with this products con'c~n~~I!'e. Do not 

reuse them. Follow manufacturer's instructions for cleaning/maintaining PPE. If no such instructions for washables, use detergent and 

hot water. Keep and wash PPE separately from other laundry. t 
I 

When handlers use closed systems, enclosed cabs, or aircraft in a manner that meets the requirements listed in the Worker Protection 

Standard (WPS) for agricultural pesticides [40 CFR 170.240 (d) [4-6)], the handler PPE requirements may be reduced or modified as 

specified in the WPS. 

User Safety Recommendations 

Users should wash hands before eating, drinking, chewing gum, using tobacco or using the toilet. 

Users should remove clothing immediately if pesticide gets inside. Then wash body thoroughly and put on clean clothing, 

Users should remove pPE immediately after handling this product. As soon as possible, wash thoroughly and change into clean 

clothing. Wash the outside of gloves before removing. 

ENVIRONMENTAL HAZARDS 

Do not apply directly to water, or to areas where surface water is present or to intertidal areas below the mean high water mark. 

Do not contaminate water when disposing of equipment washwaters. 

Do not contaminate water used for irrigation or domestic purposes. 

SPRAY DRIFT 

Avoid spray drift. Do not apply when weather conditions may cause drift. Do not allow this product to drift on to non.target areas. Drift 

may result in illegal residues or injury to adjacent crops and vegetation, in the form of leaf yellowing and defoliation. To avoid spray 

drift, DO NOT apply aerially when wind speed is greater than 10 mph or during periods of temperature inversions. Use of larger droplet 

size will also reduce spray drift. 

AVOIDING SPRAY DRIFT AT THE APPLICATION SJTE IS THE RESPONSIBILITY OF THE APPLICATOR. 

The interaction of many equipment-and·weather.related factors determine the potential for spray drift. The applicator is responsible for 

conSidering all these factors when making decisions. 

The follOwing drift management requirements must be followed to avoid off·target movement from aerial applications to agricultural field 

crops. These requirements do not apply to forestry applications, public health uses or to applications using dry formulations. 

1. The distance of the outer most nozzles on the boom must not exceed 3/4 the length of the wingspan or rotor. 

2. Nozzles must always point backward parallel with the air stream and never be pointed downwards more than 45 degrees. 

Where states have more stringent regulations, they should be observed. 

The applicator should be familiar with and take into account the information covered in the Aerial Drift Reduction Advisory below: 

AERIAL DRIFT REDUCTION ADVISORY 

[This section is advisory in nature and does not supersede the mandatory label requirements[. 

INFORMATION ON DROPLET SIZE 

The most effective way to reduce drift potential is to apply large droplets. The best drift management strategy is to apply the largest 

droplets that provide sufficient coverage and control. Applying larger droplets reduces drift potential, but will not prevent drift if 

applications are made improperly, or under unfavorable environmental conditions (See Wind, Temperature and Humidity, and 

Temperature Inversions). 

CONTROLUNG DROPLET SIZE 

Volume· Use high flow rate nozzles to apply the highest practical spray volume. Nozzles with higher rated flows produce larger 

droplets. 

Pressure· Do not exceed the nozzle manufacturer's recommended pressures. For many nozzle types lower pressure produces larger 

droplets. When higher flow rates are needed, use higher flow rate nozzles instead of increasing pressure. 

NUmber of nozzles· Use the minimum number of nozzles that provide uniform coverage. 

Nozzle Orientation· Orienting nozzles so that the spray is released parallel to the airstream produces larger dronlljt;;.than other 

orientations and is the recommended practice. Significant deflect'lon from horizontal will reduce droplet size and increaSfJ PIitt'PotentiaJ. 

Nozzle Type· Use a nozzle type that is designed for the intended application. With most nozzle types, narrower spray -€ng!es produce 

larger droplets. Consider using low..clrift nozzles. Solid stream nozzles oriented straight back produce the largest droplets and the 

lowest drift. , , , , , , , , BOOM lENGTH , > > , , 

For some use pattems, reducing the effective boom length to less than 3/4 of the 'Ningspan or rotor Mr:fJth may furth§f reduce drift 

without redUCing swath 'Nidth. \ , : \, ' ,,, " , , > 

APPUCATlQN HEJGHT 

Applications should not be made at a height greater than 10 feet above the top of the target plants unless a greater ~eight) is required 

for aircraft safety. Making applications at the lowest height that is safe reduces exposure of droplets to evaporation anrj Wlrfd.' 

") , 

2 

72

I 

When handlers use closed systems, enclosed cabs, or aircraft in a manner that meets the requirements listed in the Worker Protection 

Standard (WPS) for agricultural pesticides [40 CFR 170.240 (d) [4-6)], the handler PPE requirements may be reduced or modified as 

specified in the WPS. 

User Safety Recommendations 

Users should wash hands before eating, drinking, chewing gum, using tobacco or using the toilet. 

Users should remove clothing immediately if pesticide gets inside. Then wash body thoroughly and put on clean clothing, 

Users should remove pPE immediately after handling this product. As soon as possible, wash thoroughly and change into clean 

clothing. Wash the outside of gloves before removing. 

ENVIRONMENTAL HAZARDS 

Do not apply directly to water, or to areas where surface water is present or to intertidal areas below the mean high water mark. 

Do not contaminate water when disposing of equipment washwaters. 

Do not contaminate water used for irrigation or domestic purposes. 

SPRAY DRIFT 

Avoid spray drift. Do not apply when weather conditions may cause drift. Do not allow this product to drift on to non.target areas. Drift 

may result in illegal residues or injury to adjacent crops and vegetation, in the form of leaf yellowing and defoliation. To avoid spray 

drift, DO NOT apply aerially when wind speed is greater than 10 mph or during periods of temperature inversions. Use of larger droplet 

size will also reduce spray drift. 

AVOIDING SPRAY DRIFT AT THE APPLICATION SJTE IS THE RESPONSIBILITY OF THE APPLICATOR. 

The interaction of many equipment-and·weather.related factors determine the potential for spray drift. The applicator is responsible for 

conSidering all these factors when making decisions. 

The follOwing drift management requirements must be followed to avoid off·target movement from aerial applications to agricultural field 

crops. These requirements do not apply to forestry applications, public health uses or to applications using dry formulations. 

1. The distance of the outer most nozzles on the boom must not exceed 3/4 the length of the wingspan or rotor. 

2. Nozzles must always point backward parallel with the air stream and never be pointed downwards more than 45 degrees. 

Where states have more stringent regulations, they should be observed. 

The applicator should be familiar with and take into account the information covered in the Aerial Drift Reduction Advisory below: 

AERIAL DRIFT REDUCTION ADVISORY 

[This section is advisory in nature and does not supersede the mandatory label requirements[. 

INFORMATION ON DROPLET SIZE 

The most effective way to reduce drift potential is to apply large droplets. The best drift management strategy is to apply the largest 

droplets that provide sufficient coverage and control. Applying larger droplets reduces drift potential, but will not prevent drift if 

applications are made improperly, or under unfavorable environmental conditions (See Wind, Temperature and Humidity, and 

Temperature Inversions). 

CONTROLUNG DROPLET SIZE 

Volume· Use high flow rate nozzles to apply the highest practical spray volume. Nozzles with higher rated flows produce larger 

droplets. 

Pressure· Do not exceed the nozzle manufacturer's recommended pressures. For many nozzle types lower pressure produces larger 

droplets. When higher flow rates are needed, use higher flow rate nozzles instead of increasing pressure. 

NUmber of nozzles· Use the minimum number of nozzles that provide uniform coverage. 

Nozzle Orientation· Orienting nozzles so that the spray is released parallel to the airstream produces larger dronlljt;;.than other 

orientations and is the recommended practice. Significant deflect'lon from horizontal will reduce droplet size and increaSfJ PIitt'PotentiaJ. 

Nozzle Type· Use a nozzle type that is designed for the intended application. With most nozzle types, narrower spray -€ng!es produce 

larger droplets. Consider using low..clrift nozzles. Solid stream nozzles oriented straight back produce the largest droplets and the 

lowest drift. , , , , , , , , 

BOOM lENGTH , > > , , 

For some use pattems, reducing the effective boom length to less than 3/4 of the 'Ningspan or rotor Mr:fJth may furth§f reduce drift 

without redUCing swath 'Nidth. \ , : \, ' ,,, " , , > 

APPUCATlQN HEJGHT 

Applications should not be made at a height greater than 10 feet above the top of the target plants unless a greater ~eight) is required 

for aircraft safety. Making applications at the lowest height that is safe reduces exposure of droplets to evaporation anrj Wlrfd.' 

") , 

2 
SWATH ADJUSTMENT 

When applications are made with a crosswind, the swath will be displaced downwind. Therefore, on the up and downwind edges of the 

field, the applicator should compensate for this displacement by adjusting the path of the aircraft upwind. Swath adjustment distance 

should increase, with increasing drift potential (higher wind, smaller drops, etc.). 

WINO 

Drift potential is lowest between wind speeds of 2 - 10 mph. However, many factors, including droplet size and equipment type 

determine drift potential at any given speed. Application should be avoided below 2 mph due to variable wind direction and high 

inversion potential. NOTE: Local terrain can influence wind patterns. Every applicator should be familiar '<\lith local wind patterns and 

how they affect spray drift. 

TEMPERATURE AND HUMIDITY 

When making applications in low relative humidity, set up equipment to produce larger droplets to compensate for evaporation. Droplet 

evaporation is most severe when conditions are both hot and dry. 

TEMPERATURE INVERSIONS 

Applications should not occur during a temperature inversion because drift potential is high. Temperature inversions restrict vertical air 

mixing, which causes small suspended droplets to remain in a concentrated cloud. This cloud can move in unpredictable directions due 

to the light variable winds common during inversions. Temperature inversions are characterized by increasing temperatures with 

altitude and are common on nights with limited cloud cover and light to no wind. They begin to form as the sun sets and often continue 

into the morning. Their presence can be indicated by ground fog; however, if fog is not present, inversions can also be identified by the 

movement of smoke from a ground source or an aircraft smoke generator. Smoke that layers and moves laterally in a concentrated 

cloud (under low wind conditions) indicates an inversion, while smoke that moves upward and rapidly dissipates indicates good vertical 

air mixing. 

SENSJTJVE AREAS 

The pesticide should only be applied when the potential for drift to adjacent sensitive areas (e.g. residential areas, bodies of water, 

known habitat for threatened or endangered species, non-target crops) is minimal (e.g. when wind is blowing away from the sensitive 

areas). 

USE PRECAUTIONS 

Do not apply PREpTM brand Ethephon for Cotton and Tobacco through any type of irrigation system. 

Avoid spray drift to nearby crops as this product will cause modifications in plant growth. Plant injury or reduced yields wiU result. 

Mix only the amount of spray you expect to use each day. Do not allow mixed solution to stand overnight. 

DIRECTIONS FOR USE 

It is a violation of Federal law to use this product in a manner inconsistent with its labeling. 

Do not apply this product in a way that will contact workers or other persons, either directly or through drift. Only protected handlers 

may be in the area during application. For any requirements specific to your State or Tribe, consult the agency responsible for pesticide 

regulations. Read entire label before using this product. 

AGRICULTURAL USE REQUIREMENTS 

Use this product only in accordance with its labeling and with the Worker Protection Standard, 40 CFR part 170. This standard contains 

requirements for the protection of agricultural workers on farms, forests, nurseries, and greenhouses, and handlers of agricultural 

pesticides. It contains requirements for training, decontamination, notification, and emergency assistance. It also contains specific 

instructions and exceptions pertaining to the statements on this label about personal protective equipment (PPE), notification to workers 

and restricted-entry intervals. The requirements in this box only apply to uses of this product that are covered by the Worker Protection 

Standard. 

Do not enter or allow worker entry into treated areas during the restricted-entry interval (REI) of 48 hours. The REI is 73 nOl1rs in areas 

where average rainfall is less than 25 inches per year. ' '''" •• 

PPE required for early entry to treated areas that is permitted under the Worker Protection Standard and that involves:t.'Ojltact with 

anything that has been treated such as plants, soil or water is coveralls over long-sleeved shirt and long pants, Ch*1l1icat resistant 

gloves made of any waterproof material, such as nitrile, butyl, neoprene, or bamer laminate, chemical resiman\'fnol:viear plL-'S socks, and 

protective eyewear. For overhead exposure, chemical-resistant headgear is also required. ~ ': ,j >, , , Notify workers of the application by warning them orally and posting warning signs at entrances to treated a(~as; '" , 

, , , " 

" , , " 

, , > , 

'"' , 

3 

73

SWATH ADJUSTMENT 

When applications are made with a crosswind, the swath will be displaced downwind. Therefore, on the up and downwind edges of the 

field, the applicator should compensate for this displacement by adjusting the path of the aircraft upwind. Swath adjustment distance 

should increase, with increasing drift potential (higher wind, smaller drops, etc.). 

WINO 

Drift potential is lowest between wind speeds of 2 - 10 mph. However, many factors, including droplet size and equipment type 

determine drift potential at any given speed. Application should be avoided below 2 mph due to variable wind direction and high 

inversion potential. NOTE: Local terrain can influence wind patterns. Every applicator should be familiar '<\lith local wind patterns and 

how they affect spray drift. 

TEMPERATURE AND HUMIDITY 

When making applications in low relative humidity, set up equipment to produce larger droplets to compensate for evaporation. Droplet 

evaporation is most severe when conditions are both hot and dry. 

TEMPERATURE INVERSIONS 

Applications should not occur during a temperature inversion because drift potential is high. Temperature inversions restrict vertical air 

mixing, which causes small suspended droplets to remain in a concentrated cloud. This cloud can move in unpredictable directions due 

to the light variable winds common during inversions. Temperature inversions are characterized by increasing temperatures with 

altitude and are common on nights with limited cloud cover and light to no wind. They begin to form as the sun sets and often continue 

into the morning. Their presence can be indicated by ground fog; however, if fog is not present, inversions can also be identified by the 

movement of smoke from a ground source or an aircraft smoke generator. Smoke that layers and moves laterally in a concentrated 

cloud (under low wind conditions) indicates an inversion, while smoke that moves upward and rapidly dissipates indicates good vertical 

air mixing. 

SENSJTJVE AREAS 

The pesticide should only be applied when the potential for drift to adjacent sensitive areas (e.g. residential areas, bodies of water, 

known habitat for threatened or endangered species, non-target crops) is minimal (e.g. when wind is blowing away from the sensitive 

areas). 

USE PRECAUTIONS 

Do not apply PREpTM brand Ethephon for Cotton and Tobacco through any type of irrigation system. 

Avoid spray drift to nearby crops as this product will cause modifications in plant growth. Plant injury or reduced yields wiU result. 

Mix only the amount of spray you expect to use each day. Do not allow mixed solution to stand overnight. 

DIRECTIONS FOR USE 

It is a violation of Federal law to use this product in a manner inconsistent with its labeling. 

Do not apply this product in a way that will contact workers or other persons, either directly or through drift. Only protected handlers 

may be in the area during application. For any requirements specific to your State or Tribe, consult the agency responsible for pesticide 

regulations. Read entire label before using this product. 

AGRICULTURAL USE REQUIREMENTS 

Use this product only in accordance with its labeling and with the Worker Protection Standard, 40 CFR part 170. This standard contains 

requirements for the protection of agricultural workers on farms, forests, nurseries, and greenhouses, and handlers of agricultural 

pesticides. It contains requirements for training, decontamination, notification, and emergency assistance. It also contains specific 

instructions and exceptions pertaining to the statements on this label about personal protective equipment (PPE), notification to workers 

and restricted-entry intervals. The requirements in this box only apply to uses of this product that are covered by the Worker Protection 

Standard. 

Do not enter or allow worker entry into treated areas during the restricted-entry interval (REI) of 48 hours. The REI is 73 nOl1rs in areas 

where average rainfall is less than 25 inches per year. ' '''" •• 

PPE required for early entry to treated areas that is permitted under the Worker Protection Standard and that involves:t.'Ojltact with 

anything that has been treated such as plants, soil or water is coveralls over long-sleeved shirt and long pants, Ch*1l1icat resistant 

gloves made of any waterproof material, such as nitrile, butyl, neoprene, or bamer laminate, chemical resiman\'fnol:viear plL-'S socks, and 

protective eyewear. For overhead exposure, chemical-resistant headgear is also required. ~ ': ,j >, , , Notify workers of the application by warning them orally and posting warning signs at entrances to treated a(~as; '" , 

, , , " 

" , , " 

, , > , 

'"' , 

3 
STORAGE AND DISPOSAL 

Do not contaminate water, food, or feed by storage or disposal. 

PESTICIDE STORAGE 

Store in a cool, dry place and away from food, feed and other pesticides. IF SPILLED: If container is broken or contents have spilled, 

follow all precautions indicated above and clean up immediately. Before cleaning up, put on full length trousers. long sleeved shirt, 

protective gloves, and goggles or face shield. Soak up spill with absorbent media such as sand, earth or other suitable material and 

dispose of waste at an approved waste disposal facility. 

PESTICIDE DISPOSAL 

Pesticide wastes are acutely hazardous. Improper disposal of excess pesticide, spray mixture, or rinsate is a violation of Federal law. If 

these wastes cannot be disposed of by use according to label instructions, contact your State Pesticide or Environmental Control 

Agency or the Hazardous Waste representative at the nearest EPA Regional Office for guidance. 

CONTA[NER DISPOSAL 

Rigid, Non-refillable containers small enough to shake (i.e., with capacities equal to or less than 5 gallons) 

Non·refillable container. Do not reuse or refiU this container. Triple rinse or pressure rinse container (or equivalent) promptly after 

emptying. Triple rinse as follows: Empty the remaining contents into application equipment or a mix tank and drain for to seconds after 

the now begins to drip. Fill the container 1/4 fuJi with water and recap. Shake for 10 seconds. Pour rinsate inlo application equipment or 

a mix tank or store rinsate for later use or disposal. Drain for 10 seconds after the flow begins to drip. Repeat this procedure two more 

times. Once container is rinsed, offer for recycling if available or puncture and dispose of in a sanitary landfill. 

Rigid Non-refillable containers that are too large to shake ([.e., with capacities greater than 5 gallons or 50 lbs) 

Non·refillable Containers 

Non·refillable containers· Do not reuse or refill this container. Refer to Bottom Discharge IBC or Top Discharge IBC, Drums, Kegs 

information as fonows. 

Bottom Discharge IBC (e.g. - Schuetz Caged [BC or Snyder Square Stackable) 

Pressure rinsing the container before final disposal is the responsibility of the person disposing of the container. To pressure rinse the 

container before final disposal, empty the remaining contents from the IBC into application equipment or mix tank. Raise the bottom of 

the IBC by 1.5 inches on the side which is opposite of the bottom discharge valve to promote more complete product removal. 

Complete[y remove the top lid of the IBC. Use water pressurized to at least 40 PSI to rinse aI[ interior portions. Continuously pump or 

drain rinsate into application equipment or rinsate collection system while pressure rinsing. Continue pressure rinsing for 2 minutes or 

until rinsate becomes clear. Replace the lid and dose bottom valve. 

Top Discharge IBC, Drums, Kegs (e.g.- Snyder 120 Next Gen, Bonar B120, Drums, Kegs), 

Triple rinSing the container before final disposal is the responsibility of the person dispOSing of the container. To triple rinse the 

container before final disposal, empty the remaining contents from this container into application equipment or mix tank. Fill the 

container at least 10 percent full with water. Agitate vigorously or recirculate water with the pump for 2 minutes. Rinse aU interior 

surfaces. Pour or pump rinsate into apPlication equipment or rinsate collection system. Repeat this procedure two more times. Once 

container is rinsed, offer for recycling 'If avalJable or puncture and dispose of in a sanitary landfill. 

Refil[able Containers 

Refillable container- Refer to Bottom Discharge IBC or Top Discharge IBC, Drums, Kegs information as follows. Refill this container 

with pesticide only. Do not reuse this container for any other purpose. After emptying producl from container, either return conlainer to 

Bayer CropScience per instructions from Bayer CropScience Customer Service Center (1·800-527-4781) or rinse and either recycle or 

dispose of the container as follows'. 

Bottom Discharge IBC (e.g. -Schuetz Caged IBC or Snyder Square Stackab[e) 

Pressure rinsing the container before final disposal is the responsibility of the person disposing of the container. Cleaning before refilling 

is the responsibility of the refiller. To pressure rinse the container before final disposal, empty the remaining contents fr.o'hi fhe.IBC into 

application equipment or mix tank. Raise the bottom of the IBC by 1.5 inches on the side which is opposite of the bottom ai~eharge 

valve to promote more complete product removal. Completely remove the top lid of the IBC. Use water pressurized to -'}t'le~st.40 PSI to 

rinse all interior portions. Continuously pump or drain rinsate into application equipment or rinsate collection system while'Pressure 

rinsing. Continue pressure rinsing for 2 minutes or until rinsate becomes dear. Replace the lid and c[ose;DGttp7l1 valve. 

Top Discharge IBC, Drums, Kegs (e.9.- Snyder 120 Next Gen, Bonar B120, Drums, Kegs). , , , , 

Triple rinsing the container before final disposal is the responsibility of the person disposing of the containel'. >C,!tlaning 9§!for~ refiJJing is 

the responsibility of the refiner. To triple rinse the containers before final disposal, empty the remaining contents from i:lis'COn:ainer into 

application equipment or mix tank. Fill the container at least 10 percent full with water. Agitate vigorously' or~reci7culate Jwater wilh the 

pump for 2 minutes. Rinse aU interior surfaces. Pour or pump rinsate into application eqUipment or rinsate ~cJolJiktion system. Repeat this 

procedure two more times. Once container is rinsed, offer for recyding if available or puncture and dispose of in a sanl:!?J'j JarJ:lfill. 

." , 

4 

74

STORAGE AND DISPOSAL 

Do not contaminate water, food, or feed by storage or disposal. 

PESTICIDE STORAGE 

Store in a cool, dry place and away from food, feed and other pesticides. IF SPILLED: If container is broken or contents have spilled, 

follow all precautions indicated above and clean up immediately. Before cleaning up, put on full length trousers. long sleeved shirt, 

protective gloves, and goggles or face shield. Soak up spill with absorbent media such as sand, earth or other suitable material and 

dispose of waste at an approved waste disposal facility. 

PESTICIDE DISPOSAL 

Pesticide wastes are acutely hazardous. Improper disposal of excess pesticide, spray mixture, or rinsate is a violation of Federal law. If 

these wastes cannot be disposed of by use according to label instructions, contact your State Pesticide or Environmental Control 

Agency or the Hazardous Waste representative at the nearest EPA Regional Office for guidance. 

CONTA[NER DISPOSAL 

Rigid, Non-refillable containers small enough to shake (i.e., with capacities equal to or less than 5 gallons) 

Non·refillable container. Do not reuse or refiU this container. Triple rinse or pressure rinse container (or equivalent) promptly after 

emptying. Triple rinse as follows: Empty the remaining contents into application equipment or a mix tank and drain for to seconds after 

the now begins to drip. Fill the container 1/4 fuJi with water and recap. Shake for 10 seconds. Pour rinsate inlo application equipment or 

a mix tank or store rinsate for later use or disposal. Drain for 10 seconds after the flow begins to drip. Repeat this procedure two more 

times. Once container is rinsed, offer for recycling if available or puncture and dispose of in a sanitary landfill. 

Rigid Non-refillable containers that are too large to shake ([.e., with capacities greater than 5 gallons or 50 lbs) 

Non·refillable Containers 

Non·refillable containers· Do not reuse or refill this container. Refer to Bottom Discharge IBC or Top Discharge IBC, Drums, Kegs 

information as fonows. 

Bottom Discharge IBC (e.g. - Schuetz Caged [BC or Snyder Square Stackable) 

Pressure rinsing the container before final disposal is the responsibility of the person disposing of the container. To pressure rinse the 

container before final disposal, empty the remaining contents from the IBC into application equipment or mix tank. Raise the bottom of 

the IBC by 1.5 inches on the side which is opposite of the bottom discharge valve to promote more complete product removal. 

Complete[y remove the top lid of the IBC. Use water pressurized to at least 40 PSI to rinse aI[ interior portions. Continuously pump or 

drain rinsate into application equipment or rinsate collection system while pressure rinsing. Continue pressure rinsing for 2 minutes or 

until rinsate becomes clear. Replace the lid and dose bottom valve. 

Top Discharge IBC, Drums, Kegs (e.g.- Snyder 120 Next Gen, Bonar B120, Drums, Kegs), 

Triple rinSing the container before final disposal is the responsibility of the person dispOSing of the container. To triple rinse the 

container before final disposal, empty the remaining contents from this container into application equipment or mix tank. Fill the 

container at least 10 percent full with water. Agitate vigorously or recirculate water with the pump for 2 minutes. Rinse aU interior 

surfaces. Pour or pump rinsate into apPlication equipment or rinsate collection system. Repeat this procedure two more times. Once 

container is rinsed, offer for recycling 'If avalJable or puncture and dispose of in a sanitary landfill. 

Refil[able Containers 

Refillable container- Refer to Bottom Discharge IBC or Top Discharge IBC, Drums, Kegs information as follows. Refill this container 

with pesticide only. Do not reuse this container for any other purpose. After emptying producl from container, either return conlainer to 

Bayer CropScience per instructions from Bayer CropScience Customer Service Center (1·800-527-4781) or rinse and either recycle or 

dispose of the container as follows'. 

Bottom Discharge IBC (e.g. -Schuetz Caged IBC or Snyder Square Stackab[e) 

Pressure rinsing the container before final disposal is the responsibility of the person disposing of the container. Cleaning before refilling 

is the responsibility of the refiller. To pressure rinse the container before final disposal, empty the remaining contents fr.o'hi fhe.IBC into 

application equipment or mix tank. Raise the bottom of the IBC by 1.5 inches on the side which is opposite of the bottom ai~eharge 

valve to promote more complete product removal. Completely remove the top lid of the IBC. Use water pressurized to -'}t'le~st.40 PSI to 

rinse all interior portions. Continuously pump or drain rinsate into application equipment or rinsate collection system while'Pressure 

rinsing. Continue pressure rinsing for 2 minutes or until rinsate becomes dear. Replace the lid and c[ose;DGttp7l1 valve. 

Top Discharge IBC, Drums, Kegs (e.9.- Snyder 120 Next Gen, Bonar B120, Drums, Kegs). , , , , 

Triple rinsing the container before final disposal is the responsibility of the person disposing of the containel'. >C,!tlaning 9§!for~ refiJJing is 

the responsibility of the refiner. To triple rinse the containers before final disposal, empty the remaining contents from i:lis'COn:ainer into 

application equipment or mix tank. Fill the container at least 10 percent full with water. Agitate vigorously' or~reci7culate Jwater wilh the 

pump for 2 minutes. Rinse aU interior surfaces. Pour or pump rinsate into application eqUipment or rinsate ~cJolJiktion system. Repeat this 

procedure two more times. Once container is rinsed, offer for recyding if available or puncture and dispose of in a sanl:!?J'j JarJ:lfill. 

." , 

4 
Refillable Containers 

End users are authorized to remove tamper evident cables as required to remove the product from the container unless the container is 

equipped with one way valves and refilling or returning is planned. If this is the case, end users are not authorized to remove tamper 

evident cables, one way valves or clean container. See Container Disposal instructions under Storage and Disposal. 

GENERAL INFORMATION 

COTTON 

A foliar spray of PREP"'" brand Ethephon for Cotton and Tobacco will accelerate opening of mature unopened cotton bolls and enhance 

defoliation w11ich can result in earlier harvest with an increased recoverable yield. PREpTM brand Ethephon for Cotton and Tobacoo 

treatment on cotton al/ows increased efficiency from a once-over harvest. 

TOBACCO (FLUE-CURED): A foliar spray of PREpTM brand Ethephon for Cotton and Tobacco promotes early, uniform "yeHowing" of 

mature tobacco. PREpTM brand Ethephon for Cotton and Tobacco reduces curing time, allowing more efficient use of curing barn 

space, and increased control over harvest schedules. 

SPRAY PREPARATION 

Add f/2 to 3/4 of the required amount of water to the spray tank. Start agitation. Add the required amount of PREpTM brand Ethephon 

for Cotton and Tobacco, and the remain'lng amount of water, Prepare only as much spray solution as can be used on the day of mixing. 

Do not allow spray solution to stand overnight. Do not spill the concentrated product on spray equipment, or any airplane parts. 

ANY SPILLS SHOULD BE RINSED IMMEDIATELY WITH PLENTY OF WATER. 

Use of a nurse tank is highly recommended for avoiding possible spills of concentrated formulation on spray equipment or any airplane 

parts, 

TANK MIXTIJRESWITH DEFOLIANTS AND INSECT/CIDES 

PREP"'" brand Ethephon for Cotton and Tobacco is compatible with DEF®, FOLEX®, Dropp®, Dropp® UltraTM, Ginstar®, Harvade®, 

Methyl Parathion, Guthion®, and MalathionTM, PREpTM brand Ethephon for Cotton and Tobacco may be applied in sequence or as a 

tank mixture (DO NOT TANK MIX WITH DESICCANTS IF COTTON IS TO BE SPINDLE HARVESTED). Follow all applicable use 

precautions and rate per acre recommendations on labels of products applied as tank mixtures or in sequence with PREP TM brand 

Ethephon for Cotton and Tobacco. In some cases slight reduction in boll opening response has been observed when tank mixes with 

defoliants were used. 

Good agitation in the spray tank is essential and a tank mixture should not be allowed to stand without agitation fOr more than 5 to 10 

minutes. Read and observe all appropriate label use directions and precautions for the defoliants and insecticides used. 

NOTE: UNDER CERTAIN CONDITIONS, TANK MIXTURES OF PREpm BRAND ETHEPHON FOR COTTON AND TOBACCO WITH 

DESICCANTS CONTAINING SODIUM CHLORATE COULD RESULT IN THE FORMATION OF HYPOCHLOROUS ACIDS WHICH 

ON HEATING WILL EMIT TOXIC CHLORIDE FUMES. 

DO NOT MIX PREpTM BRAND ETHEPHON FOR COTTON AND TOBACCO WITH AMMONIUM THiOSULFATE. SUCH TANK 

MIXTURES MAY RESULT IN FORMATION OF TOXIC FUMES. 

EQUIPMENT CLEANING 

Because of the acidic nature of this product, prolonged exposure to spray deposit will damage acrylic plastiCS, certain paints, and 

metals. 

Rinse thoroughly with a detergent and water all exposed acryliC plastic-type materials (e.g., aircraft windshields). and painted surfaces 

within an hour after exposure to spray depOSits. 

At the end of each day, rinse thoroughly with a detergent and water all the metal parts of the aircraft and the associated spray 

equipment exposed to the spray deposits. 

, " , " , , 

, " " , 

, , > • 

'" , 

'" , 

, , , , , , 

, , , > 

." , 

5 

75

Refillable Containers 

End users are authorized to remove tamper evident cables as required to remove the product from the container unless the container is 

equipped with one way valves and refilling or returning is planned. If this is the case, end users are not authorized to remove tamper 

evident cables, one way valves or clean container. See Container Disposal instructions under Storage and Disposal. 

GENERAL INFORMATION 

COTTON 

A foliar spray of PREP"'" brand Ethephon for Cotton and Tobacco will accelerate opening of mature unopened cotton bolls and enhance 

defoliation w11ich can result in earlier harvest with an increased recoverable yield. PREpTM brand Ethephon for Cotton and Tobacoo 

treatment on cotton al/ows increased efficiency from a once-over harvest. 

TOBACCO (FLUE-CURED): A foliar spray of PREpTM brand Ethephon for Cotton and Tobacco promotes early, uniform "yeHowing" of 

mature tobacco. PREpTM brand Ethephon for Cotton and Tobacco reduces curing time, allowing more efficient use of curing barn 

space, and increased control over harvest schedules. 

SPRAY PREPARATION 

Add f/2 to 3/4 of the required amount of water to the spray tank. Start agitation. Add the required amount of PREpTM brand Ethephon 

for Cotton and Tobacco, and the remain'lng amount of water, Prepare only as much spray solution as can be used on the day of mixing. 

Do not allow spray solution to stand overnight. Do not spill the concentrated product on spray equipment, or any airplane parts. 

ANY SPILLS SHOULD BE RINSED IMMEDIATELY WITH PLENTY OF WATER. 

Use of a nurse tank is highly recommended for avoiding possible spills of concentrated formulation on spray equipment or any airplane 

parts, 

TANK MIXTIJRESWITH DEFOLIANTS AND INSECT/CIDES 

PREP"'" brand Ethephon for Cotton and Tobacco is compatible with DEF®, FOLEX®, Dropp®, Dropp® UltraTM, Ginstar®, Harvade®, 

Methyl Parathion, Guthion®, and MalathionTM, PREpTM brand Ethephon for Cotton and Tobacco may be applied in sequence or as a 

tank mixture (DO NOT TANK MIX WITH DESICCANTS IF COTTON IS TO BE SPINDLE HARVESTED). Follow all applicable use 

precautions and rate per acre recommendations on labels of products applied as tank mixtures or in sequence with PREP TM brand 

Ethephon for Cotton and Tobacco. In some cases slight reduction in boll opening response has been observed when tank mixes with 

defoliants were used. 

Good agitation in the spray tank is essential and a tank mixture should not be allowed to stand without agitation fOr more than 5 to 10 

minutes. Read and observe all appropriate label use directions and precautions for the defoliants and insecticides used. 

NOTE: UNDER CERTAIN CONDITIONS, TANK MIXTURES OF PREpm BRAND ETHEPHON FOR COTTON AND TOBACCO WITH 

DESICCANTS CONTAINING SODIUM CHLORATE COULD RESULT IN THE FORMATION OF HYPOCHLOROUS ACIDS WHICH 

ON HEATING WILL EMIT TOXIC CHLORIDE FUMES. 

DO NOT MIX PREpTM BRAND ETHEPHON FOR COTTON AND TOBACCO WITH AMMONIUM THiOSULFATE. SUCH TANK 

MIXTURES MAY RESULT IN FORMATION OF TOXIC FUMES. 

EQUIPMENT CLEANING 

Because of the acidic nature of this product, prolonged exposure to spray deposit will damage acrylic plastiCS, certain paints, and 

metals. 

Rinse thoroughly with a detergent and water all exposed acryliC plastic-type materials (e.g., aircraft windshields). and painted surfaces 

within an hour after exposure to spray depOSits. 

At the end of each day, rinse thoroughly with a detergent and water all the metal parts of the aircraft and the associated spray 

equipment exposed to the spray deposits. 

, " , " , , 

, " " , 

, , > • 

'" , 

'" , 

, , , , , , 

, , , > 

." , 

5 
COTTON 

USE EXPECTED PREP"" BRAND ONE GAllON MINIMUM SPRAY APPLICATION 

CONOJTlONS ETHEPHON fOR PREpn.. VOLUMES TIMING 

COTTON AND BRAND (Gals/A)' 

TOBACCO ETHEPHON 

RATE FOR COTTON 

AND 

TOBACCO 

TREATS 

Pints/A LB5A.I. Acres Ground Air'''' 

PREP"" brand Hot and dry BO°F or t 1/3 1.0 6 Apply when the number of 

ETHEPHON FOR higher mature unopened boUs ;s 

CDTTONANO Dry and 7510 BO°F 2 1.5 • sufficient to produce the 

TOBACCO to 2 desired crop. See below for 

Boll Opener" Cool but above 6SoF 22/3 2.0 3 test of boll maturity. 

Treatment unitormly opens oc bolls 7 to 14 days earlier. 

Rank cotton 

PREP"" brand High soil moisture 113 0.25 2. 10 5 Apply 4 to 7 days prior to 

ETHEPHON FOR oc PREpTM brand Ethephon for 

COTTON AND High fertility level Cotion aod Tobacco boll 

TQBACCO+FDlEX$ opening application. To be 

oc used as a sequential Defoliant Tank Mix'" Rank cotton treatment with, not in place 

of PREpTM brand Ethephon 

for Cotton and Tobacco boll 

ooenina treatment 

PREP"" brand High soil moisture (/3 0.25 2. 10 3 Apply 4 to 7 days prior to 

ETHEPHON FOR oc PREpTM brand Ethephon for 

conaN AND High fertility level Cotton aod Tobacco boll 

TOBACCO + Dropp opening application. To be 

oc used as a sequential Defoliant Tank Mix'" 

Rank cotton treatment with, not in place 

of PREpTM brand Ethephon 

for Cotton and Tobacco boll 

openina treatment 

Pre·Conditioner roc Hot, dry, above 213 0.5 12 Apply 4 to 7 days prior to 

Defoliation BO°F t 1/3 1.0 6 10 2 detoliant. Enhances top 

Cool, above 65°F crop defoliation reducing 

oc 

deterioration of bottom crop 

aod allows foc earlier 

Rank cotton harvest. 

" For best performance, by ground or air application, choose equipment and spray volumes that will insure uniform coverage of foliage 

and bolls. 

*" Pretreatment With Defoliants Prior to PREpTM brand Ethephon for Cotton and Tobacco Boll Opening Treatment: If the cotton is overly 

rank or laying down in the middles and good spray coverage of the bolls with PREpTM brand Ethephon for Cotton and Tobacco is 

difficult, a pretreatment with defoliants will be useful to improve boll coverage with PREpTM brand Ethephon for Cotict)smd Tobacco. 

Use dosage rates of PREpTM brand Ethephon tor Cotton and Tobacco recommended for boll opening. Read ano;:l.dbserve all 

appropriate label use directions and precautions for the defoliant used. } • , > 

"** Can use up to fUll label rate for each product. 

"*** In California and Arizona use a volume of no less than 5 gallons per acre for aerial applications. 

Boll Maturity 

" ) ) , " , " 

, } > > 

A boll is mature when it is too hard to be dented when squeezed between thumb and fingers, too hard to'l;;(; sliced \"lilh a,o$harp knife, 

and when the seed coat becomes light brown in color. . , , , , " ), > > 

Use Limitations ' ~ , ) , 

Do not exceed a maximum of 2.0 lb. ethephon active ingredient per acre per year through combined or repe.atea uses of any 

ethephon products. ' ,}} } 

Boll Opening: Do not tank mix PREpTM brand Ethephon for Cotton and Tobacco with a desiccant if the cotton .10;. J9 'be spindle 

harvested. 

6 

76

COTTON 

USE EXPECTED PREP"" BRAND ONE GAllON MINIMUM SPRAY APPLICATION 

CONOJTlONS ETHEPHON fOR PREpn.. VOLUMES TIMING 

COTTON AND BRAND (Gals/A)' 

TOBACCO ETHEPHON 

RATE FOR COTTON 

AND 

TOBACCO 

TREATS 

Pints/A LB5A.I. Acres Ground Air'''' 

PREP"" brand Hot and dry BO°F or t 1/3 1.0 6 Apply when the number of 

ETHEPHON FOR higher mature unopened boUs ;s 

CDTTONANO Dry and 7510 BO°F 2 1.5 • sufficient to produce the 

TOBACCO to 2 desired crop. See below for 

Boll Opener" Cool but above 6SoF 22/3 2.0 3 test of boll maturity. 

Treatment unitormly opens oc bolls 7 to 14 days earlier. 

Rank cotton 

PREP"" brand High soil moisture 113 0.25 2. 10 5 Apply 4 to 7 days prior to 

ETHEPHON FOR oc PREpTM brand Ethephon for 

COTTON AND High fertility level Cotion aod Tobacco boll 

TQBACCO+FDlEX$ opening application. To be 

oc used as a sequential Defoliant Tank Mix'" Rank cotton treatment with, not in place 

of PREpTM brand Ethephon 

for Cotton and Tobacco boll 

openinq treatment 

PREP"" brand High soil moisture (/3 0.25 2. 10 3 Apply 4 to 7 days prior to 

ETHEPHON FOR oc PREpTM brand Ethephon for 

conaN AND High fertility level Cotton aod Tobacco boll 

TOBACCO + Dropp opening application. To be 

oc used as a sequential Defoliant Tank Mix'" 

Rank cotton treatment with, not in place 

of PREpTM brand Ethephon 

for Cotton and Tobacco boll 

openinq treatment 

Pre·Conditioner roc Hot, dry, above 213 0.5 12 Apply 4 to 7 days prior to 

Defoliation BO°F t 1/3 1.0 6 10 2 detoliant. Enhances top 

Cool, above 65°F crop defoliation redUCing 

oc deterioration of bottom crop 

aod allows foc earlier 

Rank cotton harvest. 

" For best performance, by ground or air application, choose equipment and spray volumes that will insure uniform coverage of foliage 

and bolls. 

*" Pretreatment With Defoliants Prior to PREpTM brand Ethephon for Cotton and Tobacco Boll Opening Treatment: If the cotton is overly 

rank or laying down in the middles and good spray coverage of the bolls with PREpTM brand Ethephon for cotton and Tobacco is 

difficult, a pretreatment with defoliants will be useful to improve boll coverage with PREpTM brand Ethephon for Cotict)smd Tobacco. 

Use dosage rates of PREpTM brand Ethephon tor Cotton and Tobacco recommended for boll opening. Read ano;:l.dbserve all 

appropriate label use directions and precautions for the defoliant used. } • , > 

"** Can use up to fUll label rate for each product. 

"*** In California and Arizona use a volume of no less than 5 gallons per acre for aerial applications. 

Boll Maturity 

" ) ) , " , " 

, } > > 

A boll is mature when it is too hard to be dented when squeezed between thumb and fingers, too hard to'l;;(; sliced \"lilh a,o$harp knife, 

and when the seed coat becomes light brown in color. . , , , , " ), > > 

Use Limitations ' ~ , ) , 

Do not exceed a maximum of 2.0 lb. ethephon active ingredient per acre per year through combined or repe.atea uses of any 

ethephon products. ' ,}} } 

Boll Opening: Do not tank mix PREpTM brand Ethephon for Cotton and Tobacco with a desiccant if the cotton .10;. J9 'be spindle 

harvested. 

6 
" ; . J 

Pre-Condition for Defoliation: Do not tank mix PREpTM brand Ethephon for Cotton and Tobacco with desiccants unless plant 

desiccation is required. Do not use a defoliant before there is sufficient mature unopened bolls to produce the desired yield (see 

General Information section on how to test for boll maturity. 

DO NOT APPLY PREpTM BRAND ETHEPHON FOR COTTON AND TOBACCO IF RAIN IS EXPECTED WITHIN 6 HOURS. 

Rainfall within 6 hours of application may reduce product performance. 

Do not plant another crop within 30 days after treatment. Small grains planted earlier than 1 month or intercropped with the cotton 

crop to which PREpTM brand Ethephon for Cotton and Tobacco will be applied may only be used as cover crops and may not be 

harvested for food or feed. PREpTM brand Ethephon for Cotton and Tobacco may cause yellowing and growth inhibition of treated 

small grains. 

WHEN TO HARVEST COTTON 

Do not harvest cotton sooner than 7 days after a treatment with PREpTM brand Ethephon for Cotton and Tobacco. 

Observe the treated crop and harvest when optimum boll opening has been reached. Too early harvest might reduce the full advantage 

of the treatment and too late a harvest may result in reduced quality and loss of lint which will drop from the plant. 

Minimum Spray 

PREP'M brand Volumes Gallons! 

Crop Situation Ethephon for Acre 

Cotton and 

Tobacco 

Pints/Acre 

Directed Spray 1 1!3 50 

Application 

Over-The-Top 11!3-22/3 40 

Application 

USE LIMITATIONS 

TOBACCO 

(Flue-Cured Only) 

Specific Directions 

Use drop nozzles. Choose TG or OC spray tips designed to apply 50 - 60 

gpa at 35-40 psi aod at tractor speed of 2-3 mph. U,. 

2 nozzles per row; one on each side of the row dropped low enough to direct 

the spray to the leaves to be ripened and harvested. Thorough spray 

coverage is essential. With a directed spray, be sure to harvest all leaves 

with 20% or more yellowing. 

Treat only when leaves remaining on the stalk are mature. To ensure 

remaining leaves are mature, test spray several tobacco plants as described 

under the section "Proper Time of Treatment." Use the lower rate in a 

normally mature crop when experience indicates that minimum ripening 

inducement is required. Use the higher rate when the crop is heavy and has 

a tendency to be more rank or vkIen temperatures are lower than normal. 

Always test spray to determine if the tobacco is mature enough to respond to 

treatment with PREpTM brand Ethephon for Cotton and Tobacco. 

Apply over-the-top PREpTM brand Ethephon for Cotton and Tobacco spray 

as a fine mist using three nozzles (one nozzle tip over the center of the 

plant, and one on each side) so all leaves are covered thoroughly, similar to 

the application pattern of systemic sucker control agents. Use a spray 

pressure of 40 to 60 psi. 

Do not apply PREpTM brand Ethephon for Cotton and Tobacco to immature leaves as this can result in unsatisfactory coloring, 

weight loss and reduced leaf quality. 

Do not anow the crop to over ripen in the field after using PREpTM brard Ethephon for Cotton and Tobacco, since this may cause 

some reduction in yield and quality. } > , , 

Do not treat before anticipated major storm which could prevent harvest and result in crop loss. ,>., 

DO NOT APPLY PREpTM BRAND ETHEPHON FOR COTTON AND TOBACCO IF RAIN IS EXPECTED WlJHI~'~ HOURS. 

Rainfall within 6 hours of application may reduce product performance. -> ~ 

Do not use PREpTM brand Ethephon for Cotton and Tobacco with additives other than recommende6on !h16 label. , , , , , . Do not plant another crop within 30 days after treatment. 

Do not exceed a maximum of 2 Ibs ethephon active ingredient per acre per year through repeated uses oJ .ally ethe1)~on ~roducts. ., , 

• , , > 

, , > , 

7 

77

" ; . J 

Pre-Condition for Defoliation: Do not tank mix PREpTM brand Ethephon for Cotton and Tobacco with desiccants unless plant 

desiccation is required. Do not use a defoliant before there is sufficient mature unopened bolls to produce the desired yield (see 

General Information section on how to test for boll maturity. 

DO NOT APPLY PREpTM BRAND ETHEPHON FOR COTTON AND TOBACCO IF RAIN IS EXPECTED WITHIN 6 HOURS. 

Rainfall within 6 hours of application may reduce product performance. 

Do not plant another crop within 30 days after treatment. Small grains planted earlier than 1 month or intercropped with the cotton 

crop to which PREpTM brand Ethephon for Cotton and Tobacco will be applied may only be used as cover crops and may not be 

harvested for food or feed. PREpTM brand Ethephon for Cotton and Tobacco may cause yellowing and growth inhibition of treated 

small grains. 

WHEN TO HARVEST COTTON 

Do not harvest cotton sooner than 7 days after a treatment with PREpTM brand Ethephon for Cotton and Tobacco. 

Observe the treated crop and harvest when optimum boll opening has been reached. Too early harvest might reduce the full advantage 

of the treatment and too late a harvest may result in reduced quality and loss of lint which will drop from the plant. 

Minimum Spray 

PREP'M brand Volumes Gallons! 

Crop Situation Ethephon for Acre 

Cotton and 

Tobacco 

Pints/Acre 

Directed Spray 1 1!3 50 

Application 

Over-The-Top 11!3-22/3 40 

Application 

USE LIMITATIONS 

TOBACCO 

(Flue-Cured Only) 

Specific Directions 

Use drop nozzles. Choose TG or OC spray tips designed to apply 50 - 60 

gpa at 35-40 psi aod at tractor speed of 2-3 mph. U,. 

2 nozzles per row; one on each side of the row dropped low enough to direct 

the spray to the leaves to be ripened and harvested. Thorough spray 

coverage is essential. With a directed spray, be sure to harvest all leaves 

with 20% or more veliowinQ. 

Treat only when leaves remaining on the stalk are mature. To ensure 

remaining leaves are mature, test spray several tobacco plants as described 

under the section "Proper Time of Treatment." Use the lower rate in a 

normally mature crop when experience indicates that minimum ripening 

inducement is required. Use the higher rate when the crop is heavy and has 

a tendency to be more rank or vkIen temperatures are lower than normal. 

Always test spray to determine if the tobacco is mature enough to respond to 

treatment with PREpTM brand Ethephon for Cotton and Tobacco. 

Apply over-the-top PREpTM brand Ethephon for Cotton and Tobacco spray 

as a fine mist using three nozzles (one nozzle tip over the center of the 

plant, and one on each side) so all leaves are covered thoroughly, similar to 

the application pattern of systemic sucker control agents. Use a spray 

pressure of 40 to 60 osi. 

Do not apply PREpTM brand Ethephon for Cotton and Tobacco to immature leaves as this can result in unsatisfactory coloring, 

weight loss and reduced leaf quality. 

Do not anow the crop to over ripen in the field after using PREpTM brard Ethephon for Cotton and Tobacco, since this may cause 

some reduction in yield and quality. } > , , 

Do not treat before anticipated major storm which could prevent harvest and result in crop loss. ,>., 

DO NOT APPLY PREpTM BRAND ETHEPHON FOR COTTON AND TOBACCO IF RAIN IS EXPECTED WlJHI~'~ HOURS. 

Rainfall within 6 hours of application may reduce product performance. -> ~ 

Do not use PREpTM brand Ethephon for Cotton and Tobacco with additives other than recommende6on !h16 label. , , , , , . Do not plant another crop within 30 days after treatment. 

Do not exceed a maximum of 2 Ibs ethephon active ingredient per acre per year through repeated uses oJ .ally ethe1)~on ~roducts. ., , 

• , , > 

, , > , 

7 
APPLICATION TIMING 

Successful results with PREpTM brand Ethephon for Cotton and Tobacco call for treatment when leaves are mature, not overly rank 

green when sprayed. To easily determine the proper treatment timing and the number of leaves per stalk ready fOr harvest, test spray 

several plants in more than one location in each field and observe the response. Mature leaves will begin to yellow in 24 to 72 hours. 

Test leaves that fail to yellow in 72 hours are not mature and are not ready for PREpTM brand Ethephon for Cotton and Tobacco 

treatment. Wait a few days to permit further natural maturing, then make another test spray or "maturity" check. 

To avoid quality loss and or possible leaf drop, harvest any yellowed leaves prior to application. Use lower rates under most conditions. 

Limit use of higher rates to cool (below 65"F at the time of treatment) slow ripening conditions. 

When you have confinned the desired number of leaves per plant that will color, you can determine the number of acres to treat in order 

to fill the barn. 

Prepare your test spray by mixing one teaspoon of PREpTM brand Ethephon for Cotton and Tobacco in 1 quart of water. Spray each 

test plant with about 1 oz. of this mixture, covering all leaves with a fine mist. PREpTM brand Ethephon for Cotton and Tobacco will not 

color immature sprayed leaves. 

WHEN TO HARVEST 

All mature, sprayed leaves will begin to color within 24 to 72 hours after PREPTM brand Ethephon for Cotton and Tobacco application. 

The yellowing process is weather dependent; cool weather will delay, while hot, sunny weather can speed up the process. Harvest 

treated tobacco when leaves have reached the desired color intensity. 

Harvest can commence 4B hours after PREpTM brand Ethephon for Cotton and Tobacco application. To determine harvest timing and 

avoid quality loss or leaf drop, closely monitor treated crop and weather conditions. 

CURING PREpm BRAND ETHEPHON FOR COTTON AND TOBACCO TREATED TOBACCO 

Curing procedures are as much an art as a science and each cure must be judged on the basis of tobacco condition, interval between 

treatment and harvest, weather and type of curing facility before prescription temperature and ventilation schedules can be established. 

To obtain maximum quality, care must be taken to observe and control the curing process closely, especially during the late "coloring" 

and early "drying" stages of the leaf. 

PREpTM brand Ethephon for Cotton and Tobacco treated tobacco will have started the coloring process when harvested, reducing the 

time required in the coloring phase of curing. Treated tobacco should be dried faster. If tobacco leaves are green or contain some 

green when harvested, it may be necessary to color them for a few hours. If the leaves are completely yellow, temperature and 

ventilation must be adjusted in a manner to dry the tobacco as fast as possible without scalding. Once the leaf is dried (3/4 dry), you 

should follow normal procedures fOr curing. Since PREpTM brand Ethephon for Cotton and Tobacco treated leaves cure faster, treated 

and untreated leaves should not be cured together in the same barn. 

, • > , 

, , , . 

> • , , 

, , , , , 

'"' , 

8 

78

APPLICATION TIMING 

Successful results with PREpTM brand Ethephon for Cotton and Tobacco call for treatment when leaves are mature, not overly rank 

green when sprayed. To easily determine the proper treatment timing and the number of leaves per stalk ready fOr harvest, test spray 

several plants in more than one location in each field and observe the response. Mature leaves will begin to yellow in 24 to 72 hours. 

Test leaves that fail to yellow in 72 hours are not mature and are not ready for PREpTM brand Ethephon for Cotton and Tobacco 

treatment. Wait a few days to permit further natural maturing, then make another test spray or "maturity" check. 

To avoid quality loss and or possible leaf drop, harvest any yellowed leaves prior to application. Use lower rates under most conditions. 

Limit use of higher rates to cool (below 65"F at the time of treatment) slow ripening conditions. 

When you have confinned the desired number of leaves per plant that will color, you can determine the number of acres to treat in order 

to fill the barn. 

Prepare your test spray by mixing one teaspoon of PREpTM brand Ethephon for Cotton and Tobacco in 1 quart of water. Spray each 

test plant with about 1 oz. of this mixture, covering all leaves with a fine mist. PREpTM brand Ethephon for Cotton and Tobacco will not 

color immature sprayed leaves. 

WHEN TO HARVEST 

All mature, sprayed leaves will begin to color within 24 to 72 hours after PREPTM brand Ethephon for Cotton and Tobacco application. 

The yellowing process is weather dependent; cool weather will delay, while hot, sunny weather can speed up the process. Harvest 

treated tobacco when leaves have reached the desired color intensity. 

Harvest can commence 4B hours after PREpTM brand Ethephon for Cotton and Tobacco application. To determine harvest timing and 

avoid quality loss or leaf drop, closely monitor treated crop and weather conditions. 

CURING PREpm BRAND ETHEPHON FOR COTTON AND TOBACCO TREATED TOBACCO 

Curing procedures are as much an art as a science and each cure must be judged on the basis of tobacco condition, interval between 

treatment and harvest, weather and type of curing facility before prescription temperature and ventilation schedules can be established. 

To obtain maximum quality, care must be taken to observe and control the curing process closely, especially during the late "coloring" 

and early "drying" stages of the leaf. 

PREpTM brand Ethephon for Cotton and Tobacco treated tobacco will have started the coloring process when harvested, reducing the 

time required in the coloring phase of curing. Treated tobacco should be dried faster. If tobacco leaves are green or contain some 

green when harvested, it may be necessary to color them for a few hours. If the leaves are completely yellow, temperature and 

ventilation must be adjusted in a manner to dry the tobacco as fast as possible without scalding. Once the leaf is dried (3/4 dry), you 

should follow normal procedures fOr curing. Since PREpTM brand Ethephon for Cotton and Tobacco treated leaves cure faster, treated 

and untreated leaves should not be cured together in the same barn. 

, • > , 

, , , . 

> • , , 

, , , , , 

'"' , 

8 
IMPORTANT: READ BEFORE USE 

Read the entire Directions for Use, Conditions, Disclaimer of Warranties and Umitations of Liability before using this product. Jf terms 

are not acceptable, return the unopened product container at once. 

By using this product, user or buyer accepts the following Conditions, Disclaimer of Warranties and limitations of Liability. 

CONDlTtONS: The directions for use of this product are beHeved to be adequate and must be followed carefully. However, it is 

impossible to eliminate aU risks associated with the use of this product. Crop 'Injury, ineffectiveness or other unintended consequences 

may result because of such factors as weather conditions, presence of other materials, or the manner of use or application, all of which 

are beyond the control of Bayer CropScience. All such risks shalJ be assumed by the user or buyer. 

DISCLAIMER OF WARRANTIES: TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, BAYER CROP SCIENCE MAKES NO 

OTHER WARRANTIES, EXPRESS OR IMPLIED, OF MERCHANTABILITY OR OF FITNESS FOR A PARTICULAR PURPOSE OR 

OTHERWISE, THAT EXTEND BEYOND THE STATEMENTS MADE ON THIS LABEL. No agent of Bayer CropScience is authorized to 

make any warranties beyond those contained herein or to modify the warranties contained herein. TO THE EXTENT CONSISTENT 

WITH APPLICABLE LAW, BAYER CROPSCIENCE DISCLAIMS ANY LIABILITY WHATSOEVER FOR SPECIAL, INCIDENTAL OR 

CONSEQUENTIAL DAMAGES RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT. 

LIMITATIONS OF LIABILITY: TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, THE EXCLUSIVE REMEDY OF THE 

USER OR BUYER FOR ANY AND ALL LOSSES, INJURIES OR DAMAGES RESULTING FROM THE USE OR HANDLING OF THIS 

PRODUCT, WHETHER IN CONTRACT, WARRANTY, TORT, NEGLIGENCE, STRICT UAB/UTY OR OlHERWSE, SHALL NOT EXCEED THE 

PURCHASE PRICE PAID, ORATBAYER CROPSCIENCE'S ElECllON, THE REPLACEMENT OF PRODUCT. 

NET CONTENTS: 2.5 GALLONS 

Dropp, Ginstar, Def and Guthion are registered trademarks and Prep and Ultra are trademarks of Bayer. 

Folex is a registered trademark of Amvac Chemical Corporation. 

Harvade is a registered trademark of Uniroyal Company. 

Malathion is a trademark of American Cyanamid Company. 

'fy Bayer CropScience 

Bayer CropScience lP 

P.O. Box 12014, 2 T.W. Alexander Drive 

Research Triangle Park, North Carolina 27709 

1·866·99BAYER (1·866·992·2937) 

PREpTM brand Ethephon for Cotton and Tobacco (PENDING) OS/24/10. Resubmitted 06/01/10 

, , '" " , " 

) > • > 

) > > , 

, , , . 

, 

, , , , 

, " " , 

", , 

), , 

9 

79

IMPORTANT: READ BEFORE USE 

Read the entire Directions for Use, Conditions, Disclaimer of Warranties and Umitations of Liability before using this product. Jf terms 

are not acceptable, return the unopened product container at once. 

By using this product, user or buyer accepts the following Conditions, Disclaimer of Warranties and limitations of Liability. 

CONDlTtONS: The directions for use of this product are beHeved to be adequate and must be followed carefully. However, it is 

impossible to eliminate aU risks associated with the use of this product. Crop 'Injury, ineffectiveness or other unintended consequences 

may result because of such factors as weather conditions, presence of other materials, or the manner of use or application, all of which 

are beyond the control of Bayer CropScience. All such risks shalJ be assumed by the user or buyer. 

DISCLAIMER OF WARRANTIES: TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, BAYER CROP SCIENCE MAKES NO 

OTHER WARRANTIES, EXPRESS OR IMPLIED, OF MERCHANTABILITY OR OF FITNESS FOR A PARTICULAR PURPOSE OR 

OTHERWISE, THAT EXTEND BEYOND THE STATEMENTS MADE ON THIS LABEL. No agent of Bayer CropScience is authorized to 

make any warranties beyond those contained herein or to modify the warranties contained herein. TO THE EXTENT CONSISTENT 

WITH APPLICABLE LAW, BAYER CROPSCIENCE DISCLAIMS ANY LIABILITY WHATSOEVER FOR SPECIAL, INCIDENTAL OR 

CONSEQUENTIAL DAMAGES RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT. 

LIMITATIONS OF LIABILITY: TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, THE EXCLUSIVE REMEDY OF THE 

USER OR BUYER FOR ANY AND ALL LOSSES, INJURIES OR DAMAGES RESULTING FROM THE USE OR HANDLING OF THIS 

PRODUCT, WHETHER IN CONTRACT, WARRANTY, TORT, NEGLIGENCE, STRICT UAB/UTY OR OlHERWSE, SHALL NOT EXCEED THE 

PURCHASE PRICE PAID, ORATBAYER CROPSCIENCE'S ElECllON, THE REPLACEMENT OF PRODUCT. 

NET CONTENTS: 2.5 GALLONS 

Dropp, Ginstar, Def and Guthion are registered trademarks and Prep and Ultra are trademarks of Bayer. 

Folex is a registered trademark of Amvac Chemical Corporation. 

Harvade is a registered trademark of Uniroyal Company. 

Malathion is a trademark of American Cyanamid Company. 

'fy Bayer CropScience 

Bayer CropScience lP 

P.O. Box 12014, 2 T.W. Alexander Drive 

Research Triangle Park, North Carolina 27709 

1·866·99BAYER (1·866·992·2937) 

PREpTM brand Ethephon for Cotton and Tobacco (PENDING) OS/24/10. Resubmitted 06/01/10 

. , , '" ., " 

) > • > 

) > > , 

, , , , 

, " " , 

", , ), , 

9 
STORAGE AND DISPOSAL 

Do not contaminate water, food, or feed by storage or disposal. 

PESTiCIDE STORAGE 

Store in a cool, dry place and away from food, feed and other pesticides. IF SPILLED: If container is broken or contents have spilled, 

follow all precaut"lons indicated above and clean up immediately. Before cleaning up, put on full length trousers, long sleeved shirt, 

protective gloves, and goggles or face shield. Soak up spill with absorbent media such as sand, earth or other suitable material and 

dispose of waste at an approved waste disposal facility. 

PESTICIDE DISPOSAL 

Pesticide wastes are acutely hazardous. Improper disposal of excess pesticlde, spray mixture, or rinsate is a violation of Federal law. If 

these wastes cannot be disposed of by use according to label instructions, contact your State Pesticide or Environmental Control 

Agency or the Hazardous Waste representative at the nearest EPA Regional Office for guidance. 

CONTAINER DISPOSAL 

Rigid, Non-refillable containers small enough to shake (i.e., with capacities equal to or less than 5 gattons) 

Non·refillable container. Do not reuse or refill this container. Triple rinse or pressure rinse container (or equivalent) promplly after 

emptying. Triple rinse as follows: Empty the remaining contents into application equipment or a mix tank and drain for 10 seconds after 

the flow begins to drip. Fill the container 1/4 fuff with water and recap. Shake for 10 seconds. Pour rinsate into application equipment or 

a mix tank or store finsate for later use or disposal. Drain for 1 D seconds after the flow begins to drip. Repeat this procedure two more 

times. Once container is rinsed, offer for recycling if available or puncture and dispose of in a sanitary landfill. 

Rigid Non·refiltable containers that are too targe to shake (i.e., with capacities greater than 5 gallons or 50 Ibs) 

Non-refittable Containers 

Non·refillable containers - Do not reuse or refill this container. Refer to Bottom Discharge IBC or Top Discharge IBC, Drums, Kegs 

information as follows. 

Bottom DiSCharge tBC (e.g. - Schuetz Caged tBC or Snyder Square Stackable) 

Pressure rinsing the container before final disposal is the responsibility of the person disposing of the container. To pressure rinse the 

container before final disposal, empty the remaining contents from the IBC into application equipment or mix tank. Raise the bottom of 

the IBC by 1.5 inches on the side which is opposite of the bottom discharge valve to promote more complete product removal. 

Completely remove the top nd of the IBC. Use water pressurized to at least 40 PSI to rinse all interior portions. Continuously pump or 

drain rinsate into application equipment or rinsate collection system while pressure rinsing. Continue pressure rinSing for 2 minutes or 

until rinsate becomes clear. Replace the lid and close bottom valve. 

Top Discharge IBC, Drums, Kegs (e.g.-Snyder 120 Next Gen, Bonar B120, Drums, Kegs). 

Triple rinsing the container before final disposal Is the responsibility of the person disposing of the container. To triple rinse the 

container before final disposal, empty the remaining contents from this container into application equipment or mix tank. Fill the 

container at least 10 percent full with water. Agitate vigorously or recirculate water with the pump for 2 minutes. Rinse all interior 

surfaces. Pour or pump rinsate into application equipment or rinsate collection system. Repeat this procedure two more times. Once 

container is rinsed, offer for recycUng if available or puncture and dispose of in a sanitary landfill. 

Refillable Containers 

Refillable container - Refer to Bottom Discharge IBC or Top Discharge IBC, Drums, Kegs information as follows. Refill this container 

with pesticide only. Do not reuse this container for any other purpose. After emptying product from container, either return container to 

Bayer CropScience per instructions from Bayer CropScience Customer Service Center (1.800-5274781) or rinse and either recycle or 

dispose of the container as follows: 

Bottom Discharge tBC (e.g. - Schuetz Caged IBC or Snyder Square Stackabte) 

Pressure rinSing tha container before final disposal Is the responsibility of the person disposing of the container. Cleaning before refilling 

is the responsibility of the refifler. To pressure rinse the container before final disposal, empty the remaining contents froI,Htfe IBC into 

application equipment or mix tank. Raise the bottom of the IBC by 1.5 inches on the side which is opposite of the bottom ilistl'!arge 

valve to promote more complete product removal. Completely remove the top lid of the IBC. Use water pressurized to at !£as~40 PSI to 

rinse all interior portions. Continuously pump or drain rinsate into application equipment or rinsate collection system whiis,pres5ure 

rinSing. Continue pressure rinsing for 2 minutes or until rinsate becomes clear. Replace the lid and close bot!CWJ )lalve. , " 

Top Discharge IBC, Drums, Kegs (e.g.- Snyder 120 Next Gen, Bonar B120, Drums, Kegs). '" > ~ 

Triple rinSing the container before final disposal is the responsibility of the person disposing of the contairi'er.;Cle~ning before~refilling is 

the responsibility of the refiller. To triple rinse the containers before final disposal, empty the remaining contents from th'o$>(',ont~iner into 

application equipment or mix tank. Fill the container at least 10 percent full with water. Agitate vigorously 01' 'ftcfrGulale Waler~th the 

pump for 2 minutes. Rinse all interior surfaces. Pour or pump rinsate into application equipment or rinsateCdliection system! Repeat this 

procedure two more times. Once container is rinsed, offer for recycling if available or puncture and dispose of in a sani~ryJ~~d"fie"c' __ J 

• > ~, 

• 0 , , 

4 

80

STORAGE AND DISPOSAL 

Do not contaminate water, food, or feed by storage or disposal. 

PESTiCIDE STORAGE 

Store in a cool, dry place and away from food, feed and other pesticides. IF SPILLED: If container is broken or contents have spilled, 

follow all precaut"lons indicated above and clean up immediately. Before cleaning up, put on full length trousers, long sleeved shirt, 

protective gloves, and goggles or face shield. Soak up spill with absorbent media such as sand, earth or other suitable material and 

dispose of waste at an approved waste disposal facility. 

PESTICIDE DISPOSAL 

Pesticide wastes are acutely hazardous. Improper disposal of excess pesticlde, spray mixture, or rinsate is a violation of Federal law. If 

these wastes cannot be disposed of by use according to label instructions, contact your State Pesticide or Environmental Control 

Agency or the Hazardous Waste representative at the nearest EPA Regional Office for guidance. 

CONTAINER DISPOSAL 

Rigid, Non-refillable containers small enough to shake (i.e., with capacities equal to or less than 5 gattons) 

Non·refillable container. Do not reuse or refill this container. Triple rinse or pressure rinse container (or equivalent) promplly after 

emptying. Triple rinse as follows: Empty the remaining contents into application equipment or a mix tank and drain for 10 seconds after 

the flow begins to drip. Fill the container 1/4 fuff with water and recap. Shake for 10 seconds. Pour rinsate into application equipment or 

a mix tank or store finsate for later use or disposal. Drain for 1 D seconds after the flow begins to drip. Repeat this procedure two more 

times. Once container is rinsed, offer for recycling if available or puncture and dispose of in a sanitary landfill. 

Rigid Non·refiltable containers that are too targe to shake (i.e., with capacities greater than 5 gallons or 50 Ibs) 

Non-refittable Containers 

Non·refillable containers - Do not reuse or refill this container. Refer to Bottom Discharge IBC or Top Discharge IBC, Drums, Kegs 

information as follows. 

Bottom DiSCharge tBC (e.g. - Schuetz Caged tBC or Snyder Square Stackable) 

Pressure rinsing the container before final disposal is the responsibility of the person disposing of the container. To pressure rinse the 

container before final disposal, empty the remaining contents from the IBC into application equipment or mix tank. Raise the bottom of 

the IBC by 1.5 inches on the side which is opposite of the bottom discharge valve to promote more complete product removal. 

Completely remove the top nd of the IBC. Use water pressurized to at least 40 PSI to rinse all interior portions. Continuously pump or 

drain rinsate into application equipment or rinsate collection system while pressure rinsing. Continue pressure rinSing for 2 minutes or 

until rinsate becomes clear. Replace the lid and close bottom valve. 

Top Discharge IBC, Drums, Kegs (e.g.-Snyder 120 Next Gen, Bonar B120, Drums, Kegs). 

Triple rinsing the container before final disposal Is the responsibility of the person disposing of the container. To triple rinse the 

container before final disposal, empty the remaining contents from this container into application equipment or mix tank. Fill the 

container at least 10 percent full with water. Agitate vigorously or recirculate water with the pump for 2 minutes. Rinse all interior 

surfaces. Pour or pump rinsate into application equipment or rinsate collection system. Repeat this procedure two more times. Once 

container is rinsed, offer for recycUng if available or puncture and dispose of in a sanitary landfill. 

Refillable Containers 

Refillable container - Refer to Bottom Discharge IBC or Top Discharge IBC, Drums, Kegs information as follows. Refill this container 

with pesticide only. Do not reuse this container for any other purpose. After emptying product from container, either return container to 

Bayer CropScience per instructions from Bayer CropScience Customer Service Center (1.800-5274781) or rinse and either recycle or 

dispose of the container as follows: 

Bottom Discharge tBC (e.g. - Schuetz Caged IBC or Snyder Square Stackabte) 

Pressure rinSing tha container before final disposal Is the responsibility of the person disposing of the container. Cleaning before refilling 

is the responsibility of the refifler. To pressure rinse the container before final disposal, empty the remaining contents froI,Htfe IBC into 

application equipment or mix tank. Raise the bottom of the IBC by 1.5 inches on the side which is opposite of the bottom ilistl'!arge 

valve to promote more complete product removal. Completely remove the top lid of the IBC. Use water pressurized to at !£as~40 PSI to 

rinse all interior portions. Continuously pump or drain rinsate into application equipment or rinsate collection system whiis,pres5ure 

rinSing. Continue pressure rinsing for 2 minutes or until rinsate becomes clear. Replace the lid and close bot!CWJ )lalve. , " 

Top Discharge IBC, Drums, Kegs (e.g.- Snyder 120 Next Gen, Bonar B120, Drums, Kegs). '" > ~ 

Triple rinSing the container before final disposal is the responsibility of the person disposing of the contairi'er.;Cle~ning before~refilling is 

the responsibility of the refiller. To triple rinse the containers before final disposal, empty the remaining contents from th'o$>(',ont~iner into 

application equipment or mix tank. Fill the container at least 10 percent full with water. Agitate vigorously 01' 'ftcfrGulale Waler~th the 

pump for 2 minutes. Rinse all interior surfaces. Pour or pump rinsate into application equipment or rinsateCdliection system! Repeat this 

procedure two more times. Once container is rinsed, offer for recycling if available or puncture and dispose of in a sani~ryJ~~d"fiC"c' __ " 

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4 
, \ 

Refillable Containers 

End users are authorized to remove tamper evident cables as required to remove the product from the container unless the container is 

equipped with one way valves and refilling or returning is planned. If this is the case, end users are not authorized to remove tamper 

evident cables, one way valves or clean container. See Container Disposal instructions under Storage and Disposal. 

GENERAL INFORMATION 

conON 

A foliar spray of PREpTM brand Ethephon for Cotton and Tobacco will accelerate opening of mature unopened cotton bolls and enhance 

defoliation which can result in earlier harvest with an increased recoverable yield. PREpTM brand Ethephon for Cotton and Tobacoo 

treatment on cotton allows increased efficiency from a once-over harvest 

TOBACCO (FlUE.CURED): A foliar spray of PREpTM brand Ethephon for Cotton and Tobacco promotes early, uniform "yellowing" of 

mature tobacco. PREpTM brand Ethephon for Cotton and Tobacco reduces curing time, allowing more efficient use of curing barn 

space, and increased control over harvest schedules. 

SPRAY PREPARATION 

Add 1/2 to 3/4 of the required amount of water to the spray tank. Start agitation. Add the required amount of PREpTM brand Ethephon 

for Cotton and Tobacco, and the remaining amount of water. Prepare only as much spray solution as can be used on the day of mbdng. 

Do not allow spray solution to stand overnight. Do not spill the concentrated product on spray equipment. or any airplane parts. 

ANY SPILLS SHOULD BE RINSED IMMEDIATELY WITH PLENTY OF WATER. 

Use of a nurse tank is highly recommended for avoiding possible spills of concentrated formulation on spray equipment or any airplane 

parts. 

TANK MIXTURES WITH DEFOUANTS AND INSECTICIDES 

PREpTM brand Ethephon for Cotton and Tobacco is compatible with DEF®, FOLEX®, Dropp®, Dropp® UltraTM, Ginstar«>, Harvade®, 

Methyl Parathion, Guthion®, and Malathionn ... PREpTM brand E:thephon for Cotton and Tobacco may be applied in sequence or as a 

tank mixture (DO NOT TANK MIX WITH DESICCANTS IF COTTON IS TO BE SPINDLE HARVESTED). Follow all appficable use 

precautions and rate per acre recommendations on labels of products applied as tank mixtures or in sequence with PREP TM brand 

Ethephon for Cotton and Tobacco. In some cases slight reduction in boll opening response has been observed when tank mixes with 

defoliants were used. 

Good agitation in the spray tank is essential and a tank mixture should not be allowed to stand without agitation for more than 5 to 10 

minutes. Read and observe all appropriate label use directions and precautions for the defoliants and insecticides used. 

NOTE: UNDER CERTAIN CONDITIONS, TANK MIXTURES OF PREpTM BRAND ETHEPHON FOR COTTON AND TOBACCO WITH 

DESICCANTS CONTAINING SODIUM CHLORATE COULD RESULT IN THE FORMATION OF HYPOCHLOROUS ACIDS WHICH 

ON HEATING WILL EMIT TOXIC CHLORIDE FUMES. 

DO NOT MIX PREpTM BRAND ETHEPHON FOR COTTON AND TOBACCO WITH AMMONIUM THIOSULFATE. SUCH TANK 

MIXTURES MAY RESULT IN FORMATION OF TOXIC FUMES. 

EQUIFfJlENT CLEANING 

Because of the acidic nature of this product, prolonged exposure to spray deposit will damage acrylic plastics, certain paints, and 

metals. 

Rinse thoroughly with a detergent and water all exposed acrylic plastic-type materials (e.g., aircraft windshields), and painted surfaces 

within an hour after exposure to spray deposits. 

At the end of each day, rinse thoroughly with a detergent and water all the metal parts of the aircraft and the associated spray 

equipment exposed to the spray deposits. 

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81

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Refillable Containers 

End users are authorized to remove tamper evident cables as required to remove the product from the container unless the container is 

equipped with one way valves and refilling or returning is planned. If this is the case, end users are not authorized to remove tamper 

evident cables, one way valves or clean container. See Container Disposal instructions under Storage and Disposal. 

GENERAL INFORMATION 

conON 

A foliar spray of PREpTM brand Ethephon for Cotton and Tobacco will accelerate opening of mature unopened cotton bolls and enhance 

defoliation which can result in earlier harvest with an increased recoverable yield. PREpTM brand Ethephon for Cotton and Tobacoo 

treatment on cotton allows increased efficiency from a once-over harvest 

TOBACCO (FlUE.CURED): A foliar spray of PREpTM brand Ethephon for Cotton and Tobacco promotes early, uniform "yellowing" of 

mature tobacco. PREpTM brand Ethephon for Cotton and Tobacco reduces curing time, allowing more efficient use of curing barn 

space, and increased control over harvest schedules. 

SPRAY PREPARATION 

Add 1/2 to 3/4 of the required amount of water to the spray tank. Start agitation. Add the required amount of PREpTM brand Ethephon 

for Cotton and Tobacco, and the remaining amount of water. Prepare only as much spray solution as can be used on the day of mbdng. 

Do not allow spray solution to stand overnight. Do not spill the concentrated product on spray equipment. or any airplane parts. 

ANY SPILLS SHOULD BE RINSED IMMEDIATELY WITH PLENTY OF WATER. 

Use of a nurse tank is highly recommended for avoiding possible spills of concentrated formulation on spray equipment or any airplane 

parts. 

TANK MIXTURES WITH DEFOUANTS AND INSECTICIDES 

PREpTM brand Ethephon for Cotton and Tobacco is compatible with DEF®, FOLEX®, Dropp®, Dropp® UltraTM, Ginstar«>, Harvade®, 

Methyl Parathion, Guthion®, and Malathionn ... PREpTM brand E:thephon for Cotton and Tobacco may be applied in sequence or as a 

tank mixture (DO NOT TANK MIX WITH DESICCANTS IF COTTON IS TO BE SPINDLE HARVESTED). Follow all appficable use 

precautions and rate per acre recommendations on labels of products applied as tank mixtures or in sequence with PREP TM brand 

Ethephon for Cotton and Tobacco. In some cases slight reduction in boll opening response has been observed when tank mixes with 

defoliants were used. 

Good agitation in the spray tank is essential and a tank mixture should not be allowed to stand without agitation for more than 5 to 10 

minutes. Read and observe all appropriate label use directions and precautions for the defoliants and insecticides used. 

NOTE: UNDER CERTAIN CONDITIONS, TANK MIXTURES OF PREpTM BRAND ETHEPHON FOR COTTON AND TOBACCO WITH 

DESICCANTS CONTAINING SODIUM CHLORATE COULD RESULT IN THE FORMATION OF HYPOCHLOROUS ACIDS WHICH 

ON HEATING WILL EMIT TOXIC CHLORIDE FUMES. 

DO NOT MIX PREpTM BRAND ETHEPHON FOR COTTON AND TOBACCO WITH AMMONIUM THIOSULFATE. SUCH TANK 

MIXTURES MAY RESULT IN FORMATION OF TOXIC FUMES. 

EQUIFfJlENT CLEANING 

Because of the acidic nature of this product, prolonged exposure to spray deposit will damage acrylic plastics, certain paints, and 

metals. 

Rinse thoroughly with a detergent and water all exposed acrylic plastic-type materials (e.g., aircraft windshields), and painted surfaces 

within an hour after exposure to spray deposits. 

At the end of each day, rinse thoroughly with a detergent and water all the metal parts of the aircraft and the associated spray 

equipment exposed to the spray deposits. 

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5 
IMPORTANT: READ BEFORE USE 

Read the entire Directions for Use, Conditions, Disclaimer of Warranties and Limitations of Liability before using this product. If terms 

are not acceptable, return the unopened product container at once. 

By using this product, user or buyer accepts the following Conditions, Disclaimer of Warranties and Limitations of Liability. 

CONDITIONS: The directions for use of this product are believed to be adequate and must be followed carefully. However, it is 

impossible to eliminate all risks assocfated with the use of this product. Crop injury, Ineffectiveness or other unintended consequences 

may result because of such factors as weather conditions, presence of other male rials, or the manner of use or application, all of which 

are beyond the control of Bayer CropScience. All such risks shall be assumed by the user or buyer. 

DISCLAIMER OF WARRANTIES: TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, BAYER CROPSCIENCE MAKES NO 

OTHER WARRANTIES, EXPRESS OR IMPLIED, OF MERCHANTABILITY OR OF FITNESS FOR A PARTICULAR PURPOSE OR 

OTHERWISE, THAT EXTEND BEYOND THE STATEMENTS MADE ON THIS LABEL. No agent of Bayer CropScience is authorized to 

make any warranties beyond those contained herein or to modify the warranties contained herein. TO THE EXTENT CONSISTENT 

WITH APPLICABLE LAW, BAYER CROPSCIENCE DISCLAIMS ANY LIABILITY WHATSOEVER FOR SPECIAL, INCIDENTAL OR 

CONSEQUENTIAL DAMAGES RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT. 

LIMITATIONS OF LIABILITY: TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, THE EXCLUSIVE REMEDY OF THE 

USER OR BUYER FOR ANY AND ALL LOSSES, INJURIES OR DAMAGES RESULTING FROM THE USE OR HANDLING OF THIS 

PRODUCT, WHETHER IN CONTAACT, WARRANTY, 'TDRT, NEGlIGENCE, STRICT UABlUTY OR OTHERWSE, SHAll NOT EXCEED THE 

PURGI-lASE PRICE P..AJD, OR AT BA. YER CROPSCIENCE'S ELECllON, THE REPLACEMENT OF PRODUCT. 

NET CONTENTS: 2.5 GALLONS 

Dropp, Ginstar, Def and Guthion are registered trademarks and Prep and Ultra are trademarks of Bayer. 

Folex is a registered trademark of Amvac Chemical Corporation. 

Harvade is a registered trademark of Uniroyal Company. 

Malathion is a trademark of American Cyanamid Company. 

4 Bayer CropScience 

Bayer CropScience LP 

P.O. Box 12014. 2 T.W. Alexander Drive 

Research Triangle Park. North Carolina 27709 

1-866-99BAYER (1-866-992-2937) 

PREpTM brand Ethephon for Cotton and Tobacco (PENDING) 05/24/10, Resubmitted 06/01/10 

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9 

82

IMPORTANT: READ BEFORE USE 

Read the entire Directions for Use, Conditions, Disclaimer of Warranties and Limitations of Liability before using this product. If terms 

are not acceptable, return the unopened product container at once. 

By using this product, user or buyer accepts the following Conditions, Disclaimer of Warranties and Limitations of Liability. 

CONDITIONS: The directions for use of this product are believed to be adequate and must be followed carefully. However, it is 

impossible to eliminate all risks assocfated with the use of this product. Crop injury, Ineffectiveness or other unintended consequences 

may result because of such factors as weather conditions, presence of other male rials, or the manner of use or application, all of which 

are beyond the control of Bayer CropScience. All such risks shall be assumed by the user or buyer. 

DISCLAIMER OF WARRANTIES: TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, BAYER CROPSCIENCE MAKES NO 

OTHER WARRANTIES, EXPRESS OR IMPLIED, OF MERCHANTABILITY OR OF FITNESS FOR A PARTICULAR PURPOSE OR 

OTHERWISE, THAT EXTEND BEYOND THE STATEMENTS MADE ON THIS LABEL. No agent of Bayer CropScience is authorized to 

make any warranties beyond those contained herein or to modify the warranties contained herein. TO THE EXTENT CONSISTENT 

WITH APPLICABLE LAW, BAYER CROPSCIENCE DISCLAIMS ANY LIABILITY WHATSOEVER FOR SPECIAL, INCIDENTAL OR 

CONSEQUENTIAL DAMAGES RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT. 

LIMITATIONS OF LIABILITY: TO THE EXTENT CONSISTENT WITH APPLICABLE LAW, THE EXCLUSIVE REMEDY OF THE 

USER OR BUYER FOR ANY AND ALL LOSSES, INJURIES OR DAMAGES RESULTING FROM THE USE OR HANDLING OF THIS 

PRODUCT, WHETHER IN CONTAACT, WARRANTY, 'TDRT, NEGlIGENCE, STRICT UABlUTY OR OTHERWSE, SHAll NOT EXCEED THE 

PURGI-lASE PRICE P..AJD, OR AT BA. YER CROPSCIENCE'S ELECllON, THE REPLACEMENT OF PRODUCT. 

NET CONTENTS: 2.5 GALLONS 

Dropp, Ginstar, Def and Guthion are registered trademarks and Prep and Ultra are trademarks of Bayer. 

Folex is a registered trademark of Amvac Chemical Corporation. 

Harvade is a registered trademark of Uniroyal Company. 

Malathion is a trademark of American Cyanamid Company. 

4 Bayer CropScience 

Bayer CropScience LP 

P.O. Box 12014. 2 T.W. Alexander Drive 

Research Triangle Park. North Carolina 27709 

1-866-99BAYER (1-866-992-2937) 

PREpTM brand Ethephon for Cotton and Tobacco (PENDING) 05/24/10, Resubmitted 06/01/10 

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) 

UNITED STATES ENVIRONMENTAL PROTECTION AGENCY 

WASHINGTON, D.C. 20460 

November 10, 2009 

Mr. Mel Tolliver 

Bayer CropScience LP 

2 T.W. Alexander Drive, 

Research Triangle Park, NC 27709 

OFFICE OF 

PREVENTION, PESTICIDES 

=-=-=-=-::-=._.....At>lQTOXICSUBSTANCES 

I~~ © lE 0 m ····.1 

lRI NOV 1 9 10J9 ;" 

By 

Subject: EPA accepted Bayer CropScience label template with modified container 

disposal and residue removal language 

OearMr. Tolliver: 

Pursuant to 40 CFR 156.140(c) and 156,144(d), Bayer CropScience (BCS) 

requested modifications to the container disposal and residue removal language in 40 

CFR part 156 and PR Notice 2007-4. EPA has reviewed BCS's proposed label 

instructions on handling, rinsing and disposal of both nonrefillable and refillable 

containers of seed treatment and non-seed treatment products and has determined that 

the language in Attachment 1 is acceptable and that label amendments incorporating the 

language in Attachment 1 can be approved. Please note that two editorial changes have 

been made to your October 10, 2009 draft by (1) inserting the word "by" before 

"incineration" in the last sentence under the heading "Non-refillable Containers" for seed 

treatment products and (2) changing "inch" to '1nches" where instructions say to "Raise 

the bottom of the IBC by 1.5 inch ... " 

Although EPA believes that these alternative statements could be suitable for 

various pesticide products, this letter is not an approval of the use of such statements on 

any particular product. In order to use these statements on a pesticide product label, 

you must apply for amendment of the product registration. Such applications must 

conform to the requirements of 40 CFR 152.44 since the language is not the exact 

wording as in the statements in 40 CFR Part 156.140 through 156.156. 

The following is a summary of the changes accepted by EPA: , > , > 

... ~ 

1) Identification of Container Type Statements a H 

The federal regulations in §156.140(c) allow EPA to modify or waive t't'lA ~ : 

requirements, or permit or require alternative labeling statements} ,fo51he 

"Identification of container type" statements that include a recycliRg Or ! '>" 

reconditioning statemen1. EPA is allowing BCS to use a statement1ew§eed • UH ~ 

treatment products in nonrefillable containers that is different than th~'standqltl, >, 

recycling or reconditioning statements provided in §156.140(a)(3r; a ~ " .,,, J, > > > 

, , 

, > , , ; , 

, 

83

UNITED STATES ENVIRONMENTAL PROTECTION AGENCY 

WASHINGTON, D.C. 20460 

November 10, 2009 

Mr. Mel Tolliver 

Bayer CropScience LP 

2 T.W. Alexander Drive, 

Research Triangle Park, NC 27709 

OFFICE OF 

PREVENTION, PESTICIDES 

1r:=""""-;;:-;;--;;;c._.....At>lD.. TOXIC SUBSTANCES 

I~~ © lE 0 m ····.1 

lRI NOV 1 9 10J9 ;" 

Subject: EPA accepted Bayer CropScience label template with modified container 

disposal and residue removal language 

OearMr. Tolliver: 

Pursuant to 40 CFR 156.140(c) and 156,144(d), Bayer CropScience (BCS) 

requested modifications to the container disposal and residue removal language in 40 

CFR part 156 and PR Notice 2007-4. EPA has reviewed BCS's proposed label 

instructions on handling, rinsing and disposal of both nonrefillable and refillable 

containers of seed treatment and non-seed treatment products and has determined that 

the language in Attachment 1 is acceptable and that label amendments incorporating the 

language in Attachment 1 can be approved. Please note that two editorial changes have 

been made to your October 10, 2009 draft by (1) inserting the word "by" before 

"incineration" in the last sentence under the heading "Non-refillable Containers" for seed 

treatment products and (2) changing "inch" to '1nches" where instructions say to "Raise 

the bottom of the IBC by 1.5 inch ... " 

Although EPA believes that these alternative statements could be suitable for 

various pesticide products, this letter is not an approval of the use of such statements on 

any particular product. In order to use these statements on a pesticide product label, 

you must apply for amendment of the product registration. Such applications must 

conform to the requirements of 40 CFR 152.44 since the language is not the exact 

wording as in the statements in 40 CFR Part 156.140 through 156.156. 

The following is a summary of the changes accepted by EPA: , > , > 

... ~ 

1) Identification of Container Type Statements a H 

The federal regulations in §156.140(c) allow EPA to modify or waive t't'lA ~ : 

requirements, or permit or require alternative labeling statements} ,fo51he 

"Identification of container type" statements that include a recycliRg Or ! '>" 

reconditioning statemen1. EPA is allowing BCS to use a statement1ew§eed • UH ~ 

treatment products in nonrefillable containers that is different than th~'standqltl, >, 

recycling or reconditioning statements provided in §156.140(a)(3r; a ~ " .,,, J, > > > 

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• , c < 

2) Pressure-rinsing Instructions for Nonrefillable Containers that are Bottom ; c, ~; c 

Discharge IBCs ~ < ( 0' < 

The federal regulations'Ul §156.144 allow EPA to modify Dr~wRiVe th& " 

requirements, or pennlt or require alternative labeling statements, fcxcresiducc < ,< 

removal instructions. BCS asserts that the standard residue rem;; ~aH[lstruc!r.:ms < 

for nonrefillable containers that are too large to shake are impraqticql ffJr the < < < < 

nonrefillable bottom discharge IBCs. Therefore, EPA is allowing'BC'S'lo use its· 

own pressure~rinsing instructions, rather than the options in §156.146(c), for.DOth ~ • " • , ~ < ( t 

seed and non "seed treatment products In rigid, nonrefillable containers that a~~ < < 

Bottom Discharge IBCs. ' , , e < ' 

3) Triple-rinsing Instructions for Nonrefillable Containers that are Top Discharge 

IBCs, Drums and Kegs 

The federal regulations in §156.144 allow EPA to modify or waive the 

requirements, or permit or require alternative labeling statements, for residue 

removal instructions. BCS asserts that the standard residue removal instructions 

(in §156,146) for nonrefillable containers that are too large to shake are 

impractical. Therefore, EPA is allowing BCS to use its own triple-rinsing 

instructions. The BCS triple-rinsing instructions are the same for both seed and 

non~seed treatment products in rigid, nonrefillable containers that are Top 

Discharge IBCs, Drums, or Kegs, 

4) Rinsing Instructions for Refillable Containers 

The federal regulations in §156.156 require instructions on labels of 

refillable containers for rinsing the container prior to disposal, which must be 

appropriate for the characteristics and formulation of the pesticide product and 

adequate to protect human health and the environment. The regulations provide 

several options for these cleaning instructions prior to disposal, including "any 

other statement the registrant considers appropriate". Because the container 

deSigns are the same for refillable containers and nonrefillable containers, EPA is 

allowing BCS to use the same pressure rinsing statements for the refillable 

bottom discharge IBCs as for the nonr.efillable bottom discharge IBCs and the 

same triple rinsing statements fpr the refillable top discharge IBCs. drums and 

kegs as for the nonrefillable top discharge laCs, drums and kegs. 

5) Other Changes to the Container Handling Instructions 

Although not required in §156.140(b) EPA is allowing BCS to add a 

recycling or reconditioning statementfor refillable containers. In addition, BCS 

has indicated that it intends to delete the references to burn'lng, as suggested by 

EPA. 

6) Directions for Use 

Lastly, although not required, EPA is allowing BCS to add text to the 

directions for use on the labels of seed and non~seed treatment products in 

refillable containers that allow the user to remove tamper evident cables unless 

the container has one-way valves and will be refilled or returned. 

Attachment 2 explains the differences in more detail between statements in the 

federal regulations and the BCS template label. 

2 

\\ 

84

2) Pressure-rinsing Instructions for Nonrefillable Containers that are Bottom ; c, ~; c 

Discharge IBCs ~ < ( 0' < 

The federal regulations'Ul §156.144 allow EPA to modify Dr~wRiVe th& " 

requirements, or pennlt or require alternative labeling statements, fcxcresiducc < ,< 

removal instructions. BCS asserts that the standard residue rem;; ~aH[lstruc!r.:ms < 

for nonrefillable containers that are too large to shake are impraqticql ffJr the < < < < 

nonrefillable bottom discharge IBCs. Therefore, EPA is allowing'BC'S'lo use its· 

own pressure-rinsing instructions, rather than the options in §156.146(c), for.DOth ~ • " • , ~ < ( t 

seed and non-seed treatment products In rigid, nonrefillable containers that a~~ < < 

Bottom Discharge IBCs. ' , , e < ' 

3) Triple-rinsing Instructions for Nonrefillable Containers that are Top Discharge 

IBCs, Drums and Kegs 

The federal regulations in §156.144 allow EPA to modify or waive the 

requirements, or permit or require alternative labeling statements, for residue 

removal instructions. BCS asserts that the standard residue removal instructions 

(in §156,146) for nonrefillable containers that are too large to shake are 

impractical. Therefore, EPA is allowing BCS to use its own triple-rinsing 

instructions. The BCS triple-rinsing instructions are the same for both seed and 

non-seed treatment products in rigid, nonrefillable containers that are Top 

Discharge IBCs, Drums, or Kegs, 

4) Rinsing Instructions for Refillable Containers 

The federal regulations in §156.156 require instructions on labels of 

refillable containers for rinsing the container prior to disposal, which must be 

appropriate for the characteristics and formulation of the pesticide product and 

adequate to protect human health and the environment. The regulations provide 

several options for these cleaning instructions prior to disposal, including "any 

other statement the registrant considers appropriate". Because the container 

deSigns are the same for refillable containers and nonrefillable containers, EPA is 

allowing BCS to use the same pressure rinsing statements for the refillable 

bottom discharge IBCs as for the nonr.efillable bottom discharge IBCs and the 

same triple rinsing statements fpr the refillable top discharge IBCs. drums and 

kegs as for the nonrefillable top discharge laCs, drums and kegs. 

5) Other Changes to the Container Handling Instructions 

Although not required in §156.140(b) EPA is allowing BCS to add a 

recycling or reconditioning statementfor refillable containers. In addition, BCS 

has indicated that it intends to delete the references to burn'lng, as suggested by 

EPA. 

6) Directions for Use 

Lastly, although not required, EPA is allowing BCS to add text to the 

directions for use on the labels of seed and non-seed treatment products in 

refillable containers that allow the user to remove tamper evident cables unless 

the container has one-way valves and will be refilled or returned. 

Attachment 2 explains the differences in more detail between statements in the 

federal regulations and the BCS template label. 

2 
EPA recommends that, in order to facilitate the review of revised labels, you 

include a copy of this letter and the relevant page(s) from Attachment 1 each time you 

submit an amendment regarding the container handling, rinsing and disposal 

statements. 

If you have any questions, please feel free to contact me at 

kasai.jeanne@epa.gov or (703) 308-3240 or Nancy Fitz at fitz.nancy@epa.govor(703) 

305-7385. 

cc: Heather Garvie 

Nancy Fitz 

Tony Kish 

Enclosures: 

Sincerely, 

~~ Field and External Affairs Division 

Attachment 1. Sayer CropScience Label Template for Container Handling and Disposal 

Statements (§§ 156.140 - 156.156) Accepted by EPA as of November 2009 

Attachment 2. Differences between statements provided in 40 CFR part 156 and 

PR Notice 2007-4, and BCS statements accepted by EPA as of November 2009 

3 

• > • > , . o • • 

85

EPA recommends that, in order to facilitate the review of revised labels, you 

include a copy of this letter and the relevant page(s) from Attachment 1 each time you 

submit an amendment regarding the container handling, rinsing and disposal 

statements. 

If you have any questions, please feel free to contact me at 

kasai.jeanne@epa.gov or (703) 308-3240 or Nancy Fitz at fitz.nancy@epa.govor(703) 

305-7385. 

cc: Heather Garvie 

Nancy Fitz 

Tony Kish 

Enclosures: 

Sincerely, 

~~ Field and External Affairs Division 

Attachment 1. Sayer CropScience Label Template for Container Handling and Disposal 

Statements (§§ 156.140 - 156.156) Accepted by EPA as of November 2009 

Attachment 2. Differences between statements provided in 40 CFR part 156 and 

PR Notice 2007-4, and BCS statements accepted by EPA as of November 2009 

3 

• > • > , . o • • 
Attachment 1 

- Page 1 of4- < c f , , 

, 

,,' , 

,c'~' c" 

Bayer CropScience Label Template for Container Handling and p':op,osal; c' " 

Statements (§§156.140 -156.156) Accepted by EPA as of Nove.vb •• 2009."" c 

Seed Treatment Products 

, , < , 

• 

, < , , , ; 

" 

c , , 

Rigid Non-refillable containers that are too large to shake (i.e., with capacities' :'::: " 

greater than 5 gallons or 50 Ibs) 

Non-refillable Containers 

Non·reffllable containers • Do not reuse or refill this container. After emptying product 

from container, either return container to Bayer CropScience per instructions from Bayer 

CropScience Customer Service Center (1-800·527-4781), or rinse and either recycle or 

dispose of the container as follows: 

Bottom Discharge IBC (e.g. - Schuetz Caged IBC or Snyder Square Stackable) 

Pressure rinsing the container before final disposal is the responsibility of the person 

disposing of the container. To pressure rinse the container before final disposal, 

empty the remaining contents from the IBC into application equipment or mix tank. 

Raise the bottom of the 18C by 1.5 inches on the side which is opposite of the bottom 

discharge valve to promote more complete product removal. Completely remove the 

top lid of the IBC. Use water pressurized to at least 40 PSI to rinse all interior 

portions. Continuously pump or drain rinsate into application equipment or rinsate 

collection system while pressure rinsing. Continue pressure rinsing for 2 minutes or 

until rinsa~e becomes clear. Replace the lid and close bottom valve. 

Top Discharge IBC, Drums, Kegs (e.g.- Snyder 120 Next Gen, Bonar 8120, Drums, and 

Kegs). 

Triple rinsing the container before final disposal is the responsibility of the person 

disposing of the container. To triple rinse the container before final disposal, empty 

the remaining contents from this container into application equipment or mix tank. Fill 

the container at least 10 percent full with water. Agitate vigorously or recirculate water 

with the pump for 2 minutes. Rinse all interior surtaces. Pour or pump rinsate into 

application equipment or rinsate collection system. Repeat this procedure two more 

times. 

Once container is rinsed, offer for recycling if available or puncture and dispose of in a 

sanitary landfill, or by incineration. 

( \ c 

·\ 

86

Attachment 1 

- Page 1 of4-

,,' , 

,c,~. c" 

Bayer CropScience Label Template for Container Handling and p':op,osal; c' " 

Statements (§§156.140 -156.156) Accepted by EPA as of Nove.vb •• 2009.·'''. 

Seed Treatment Products 

, , , < , 

• • , < , , , ;-

co • . . c , , ' 

Rigid Non-refillable containers that are too large to shake (i.e., with capacities' :-::: " 

greater than 5 gallons or 50 Ibs) 

Non-refillable Containers 

Non·reffllable containers • Do not reuse or refill this container. After emptying product 

from container, either return container to Bayer CropScience per instructions from Bayer 

CropScience Customer Service Center (1-800·527-4781), or rinse and either recycle or 

dispose of the container as follows: 

Bottom Discharge IBC (e.g. - Schuetz Caged IBC or Snyder Square Stackable) 

Pressure rinsing the container before final disposal is the responsibility of the person 

disposing of the container. To pressure rinse the container before final disposal, 

empty the remaining contents from the IBC into application equipment or mix tank. 

Raise the bottom of the 18C by 1.5 inches on the side which is opposite of the bottom 

discharge valve to promote more complete product removal. Completely remove the 

top lid of the IBC. Use water pressurized to at least 40 PSI to rinse all interior 

portions. Continuously pump or drain rinsate into application equipment or rinsate 

collection system while pressure rinsing. Continue pressure rinsing for 2 minutes or 

until rinsa~e becomes clear. Replace the lid and close bottom valve. 

Top Discharge IBC, Drums, Kegs (e.g.- Snyder 120 Next Gen, Bonar 8120, Drums, and 

Kegs). 

Triple rinsing the container before final disposal is the responsibility of the person 

disposing of the container. To triple rinse the container before final disposal, empty 

the remaining contents from this container into application equipment or mix tank. Fill 

the container at least 10 percent full with water. Agitate vigorously or recirculate water 

with the pump for 2 minutes. Rinse all interior surtaces. Pour or pump rinsate into 

application equipment or rinsate collection system. Repeat this procedure two more 

times. 

Once container is rinsed, offer for recycling if available or puncture and dispose of in a 

sanitary landfill, or by incineration. 

( 
Attachment 1 

-Page20f4-

Bayer CropScience Label Template for Container Handling and Disposal 

Statements (§§156.140 -156.156) Accepted by EPA as of November 2009 

Seed Treatment Products in Refillable Containers 

Refillable container. Refill this container with pesticide only. Do not reuse this container 

for any other purpose. After emptying product from container, either return container to 

Bayer CropScience per instructions from Bayer CropScience Customer Service Center 

(1-800-527-4781) or rinse and either recycle or dispose of the container as follows: 

Bottom Discharge IBC (e.g. - Schuetz Caged IBC or Snyder Square Stackable) 

Pressure rinsing the container before final disposal is the responsibility of the person 

disposing of the container. Cleaning before refilling is the responsibility of the refiUer. 

To pressure rinse the container before final disposal, empty the remaining contents 

from the IBC into application equipment or mix tank. Raise the bottom of the IBC by 

1.5 inches on the side which is OPP9site of the bottom discharge valve to promote 

more complete product removal. Completely remove the top lid of the IBC, Use water 

pressurized to at least 40 PSI to rinse all interior portions. Continuously pump or drain 

rinsate into application equipment or rinsate collection system while pressure rinsing. 

Continue pressure rinsing for 2 minutes or until rinsate becomes clear. Replace the lid 

and close bottom valve. 

Top Discharge IBC, Drums, Kegs (e.g. - Snyder 120 Next Gen, Bonar B120, Drums, 

and Kegs). 

Triple rinsing the container before final disposal is the responsibility of the person 

disposing of the container. Cleaning before refilling is the responsibility of the refiller. 

To triple rinse the containers before final disposal, empty the remaining contents from 

this container into application equipment or mix tank. Fill the container at least 10 

percent full with water. Agitate vigorously or recirculate water with the pump for 2 

minutes. Rinse all interior surfaces. Pour or pump rinsate into application equipment 

or rinsate collection system. Repeat this procedure two more times. 

Once container is rinsed, offer for recycling if available or puncture and dispose of in a 

sanitary landfill or by incineration. 

Text to Add to Directions for Use on Labels of Seed Treatment Products in 

Refillable Containers 

' .. , 

Refillable Containers ' ,> ~ 

End users are authorized to remove tamper evident cables as required to remov.€! me, 

product from the container unless the container is equipped with one way' valves ai1d ~ 

refilling or returning is planned. If this is the case, end users are not!ctuthc!ized tq":. 

remOve tamper evident cables, one way valves or clean container. SAEa qqntaine~.,. ' 

Disposal instructions under Storage and Disposal. a ~ ~ • '~ ~ 

• . "", '" • 

, " > , 

87

Attachment 1 

-Page20f4-

Bayer CropScience Label Template for Container Handling and Disposal 

Statements (§§156.140 -156.156) Accepted by EPA as of November 2009 

Seed Treatment Products in Refillable Containers 

Refillable container. Refill this container with pesticide only. Do not reuse this container 

for any other purpose. After emptying product from container, either return container to 

Bayer CropScience per instructions from Bayer CropScience Customer Service Center 

(1-800-527-4781) or rinse and either recycle or dispose of the container as follows: 

Bottom Discharge IBC (e.g. - Schuetz Caged IBC or Snyder Square Stackable) 

Pressure rinsing the container before final disposal is the responsibility of the person 

disposing of the container. Cleaning before refilling is the responsibility of the refiUer. 

To pressure rinse the container before final disposal, empty the remaining contents 

from the IBC into application equipment or mix tank. Raise the bottom of the IBC by 

1.5 inches on the side which is OPP9site of the bottom discharge valve to promote 

more complete product removal. Completely remove the top lid of the IBC, Use water 

pressurized to at least 40 PSI to rinse all interior portions. Continuously pump or drain 

rinsate into application equipment or rinsate collection system while pressure rinsing. 

Continue pressure rinsing for 2 minutes or until rinsate becomes clear. Replace the lid 

and close bottom valve. 

Top Discharge IBC, Drums, Kegs (e.g. - Snyder 120 Next Gen, Bonar B120, Drums, 

and Kegs). 

Triple rinsing the container before final disposal is the responsibility of the person 

disposing of the container. Cleaning before refilling is the responsibility of the refiller. 

To triple rinse the containers before final disposal, empty the remaining contents from 

this container into application equipment or mix tank. Fill the container at least 10 

percent full with water. Agitate vigorously or recirculate water with the pump for 2 

minutes. Rinse all interior surfaces. Pour or pump rinsate into application equipment 

or rinsate collection system. Repeat this procedure two more times. 

Once container is rinsed, offer for recycling if available or puncture and dispose of in a 

sanitary landfill or by incineration. 

Text to Add to Directions for Use on Labels of Seed Treatment Products in 

Refillable Containers 

' .. , 

Refillable Containers ' ,> ~ 

End users are authorized to remove tamper evident cables as required to remov.€! me, 

product from the container unless the container is equipped with one way' valves ai1d ~ 

refilling or returning is planned. If this is the case, end users are not!ctuthc!ized tq":. 

remOve tamper evident cables, one way valves or clean container. SAEa qqntaine~.,. ' 

Disposal instructions under Storage and Disposal. a ~ ~ • '~ ~ 

• . "", '" • 

, " > , 
Attachment 1 

~Page30f4~ , , . " , , , f " 

Bayer CropScience Label Template for Container Handling and Disp(;p;;~! 

Statements (§§156.140 -156.156) Accepted by EPA as of Novembe('~G09 

, , < ~ < • , 

Non-Seed Treatment Products 

, " , , 

C , , c , 

, 

« 

" 

,-« , , 

< < ~ , 

" , 

< ~ c ~ 

, , < ~ 

Rigid Non-refillable containers that are too large to shake (i.e., with capacities' , , ~, < 

greater than 5 gallons or 50 Ibs) 

Non-refillable Containers 

Non·refiUable containers - Do not reuse or refill this container. Refer to Bottom 

Discharge IBC or Top Discharge IBC, Drums, Kegs information as follows. 

Bottom Discharge IBC (e.g. - Schuetz Caged IBC or Snyder Square Stackable) 

Pressure rinsing the container before final disposal is the responsibility of the person 

disposing of the container. To pressure rinse the container before final disposal, empty 

the remaining contents from the IBC into application equipment or mix tank. Raise the 

bottom of the IBC by 1.5 inches on the side which is opposite of the bottom discharge 

valve to promote more complete product removal. Completely remove the top lid of the 

IBC. Use water pressurized to at least 40 PSI to rinse all interior portions. Continuously 

pump or drain rinsate into application equipment or rinsate collection system while 

pressure rinsing. Continue pressure rinsing for 2 minutes or until rinsate becomes 

clear. Replace the lid and close bottom valve. 

Top Discharge IBC, Drums, Kegs (e.g.- Snyder 120 Next Gen, Bonar B120, Drums, 

Kegs). 

Triple rinsing the container before final disposal is the responsibility of the person 

disposing of the container. To triple rinse the container before final disposal, empty the 

remaining contents from this container into-application equipment or mix tank. RII the 

container at least 10 percent full with water. Agitate vigorously or recirculate water with 

the pump for 2 minutes. Rinse all interior surfaces. Pour or pump rinsate into 

application equipment or rinsate collection system. Repeat this procedure two more 

times. 

Once container is rinsed, offer for recycling if available or puncture and dispose of in a 

sanitary landfill or by Incineration. 

\,-- \\ 

88

Attachment 1 

~Page30f4~ , , . " , , , f " 

Bayer CropScience Label Template for Container Handling and Disp(;p;;~! 

Statements (§§156.140 -156.156) Accepted by EPA as of Novembe('~G09 

Non-Seed Treatment Products 

, " , , 

, , < ~ 

Rigid Non-refillable containers that are too large to shake (i.e., with capacities' , , ~, < 

greater than 5 gallons or 50 Ibs) 

Non-refillable Containers 

Non·refiUable containers - Do not reuse or refill this container. Refer to Bottom 

Discharge IBC or Top Discharge IBC, Drums, Kegs information as follows. 

Bottom Discharge IBC (e.g. - Schuetz Caged IBC or Snyder Square Stackable) 

Pressure rinsing the container before final disposal is the responsibility of the person 

disposing of the container. To pressure rinse the container before final disposal, empty 

the remaining contents from the IBC into application equipment or mix tank. Raise the 

bottom of the IBC by 1.5 inches on the side which is opposite of the bottom discharge 

valve to promote more complete product removal. Completely remove the top lid of the 

IBC. Use water pressurized to at least 40 PSI to rinse all interior portions. Continuously 

pump or drain rinsate into application equipment or rinsate collection system while 

pressure rinsing. Continue pressure rinsing for 2 minutes or until rinsate becomes 

clear. Replace the lid and close bottom valve. 

Top Discharge IBC, Drums, Kegs (e.g.- Snyder 120 Next Gen, Bonar B120, Drums, 

Kegs). 

Triple rinsing the container before final disposal is the responsibility of the person 

disposing of the container. To triple rinse the container before final disposal, empty the 

remaining contents from this container into-application equipment or mix tank. RII the 

container at least 10 percent full with water. Agitate vigorously or recirculate water with 

the pump for 2 minutes. Rinse all interior surfaces. Pour or pump rinsate into 

application equipment or rinsate collection system. Repeat this procedure two more 

times. 

Once container is rinsed, offer for recycling if available or puncture and dispose of in a 

sanitary landfill or by Incineration. 
Attachment 1 

- Page 4 of4-

Sayer CropScience Label Template for Container Handling and Disposal 

Statements (§§156.140 -156.156) Accepted by EPA as of November 2009 

Non Seed-Treatment Products in Refillable Containers 

Refillable container- Refer to Bottom Discharge IBC or Top Discharge IBC, Drums, 

Kegs information as follows. Refill this container with pesticide only. Do not reuse this 

container for any other purpose. Contact your Ag retailer or Bayer CropScience for 

container return, disposal and recycling information. 

Bottom Discharge IBC (e.g. - Schuetz Caged IBC or Snyder Square Stackable) 

Pressure rinsing the container before final disposal is the responsibility of the person 

disposing of the container. Cleaning before refilling is the responsibility of the refiller. 

To pressure rinse the container before final disposal, empty the remaining contents 

from the IBC into application equipment or mix tank. Raise the bottom of the IBC by 

1.5 inches on the side which is opposite of the bottom discharge valve to promote 

more complete product removal. Completely remove the top lid of the IBC. Use water 

pressurized to at least 40 PSI to rinse all interior portions. Continuously pump or drain 

rinsate into application equipment or rinsate collection system while pressure rinsing. 

Continue pressure rinsing for 2 minutes or until rinsate becomes clear. Replace the lid 

and close bottom valve. 

Top Discharge IBC, Drums, Kegs (e.g.- Snyder 120 Next Gen, Bonar B120, Drums, 

Kegs). 

Triple rinsing the container before final disposal is the responsibility of the person 

disposing of the container. Cleaning before refilling is the responsibility of the refiller. 

To triple rinse the containers before final disposal, empty the remaining contents from 

this container into application equipment or mix tank. Fill the container at least 10 

percent full with water. Agitate vigorously or recirculate water with the pump for 2 

minutes. Rinse all interior surfaces. Pour or pump rinsate into application equipment 

or rinsate collection system. Repeat this procedure two more times. 

Once container is rinsed, offer for recycling if available or puncture and dispose of in a 

sanitary landfill or by incineration. 

Text to Add to Directions for Use on Labels of Non-Seed Treatment Products in 

Refillable Containers , •• > , 

End users are authorized to remove tamper evident cables as required to remove' ltJt!, 

product from the container unless the container is equipped with one way valves and' 

refilling or retuming is planned. If this is the case, end users are noteuthcr;zed to • • • a ~. ~~~. 

remove tamper eVIdent cables, one way valves or clean contaIner. SftA9gntalne~u ~. 

Disposal instructions under Storage and Disposal. > ~ ~ > ,~ 

• '"~''' ,~ . • 

89

Attachment 1 

- Page 4 of4-

Sayer CropScience Label Template for Container Handling and Disposal 

Statements (§§156.140 -156.156) Accepted by EPA as of November 2009 

Non Seed-Treatment Products in Refillable Containers 

Refillable container- Refer to Bottom Discharge IBC or Top Discharge IBC, Drums, 

Kegs information as follows. Refill this container with pesticide only. Do not reuse this 

container for any other purpose. Contact your Ag retailer or Bayer CropScience for 

container return, disposal and recycling information. 

Bottom Discharge IBC (e.g. - Schuetz Caged IBC or Snyder Square Stackable) 

Pressure rinsing the container before final disposal is the responsibility of the person 

disposing of the container. Cleaning before refilling is the responsibility of the refiller. 

To pressure rinse the container before final disposal, empty the remaining contents 

from the IBC into application equipment or mix tank. Raise the bottom of the IBC by 

1.5 inches on the side which is opposite of the bottom discharge valve to promote 

more complete product removal. Completely remove the top lid of the IBC. Use water 

pressurized to at least 40 PSI to rinse all interior portions. Continuously pump or drain 

rinsate into application equipment or rinsate collection system while pressure rinsing. 

Continue pressure rinsing for 2 minutes or until rinsate becomes clear. Replace the lid 

and close bottom valve. 

Top Discharge IBC, Drums, Kegs (e.g.- Snyder 120 Next Gen, Bonar B120, Drums, 

Kegs). 

Triple rinsing the container before final disposal is the responsibility of the person 

disposing of the container. Cleaning before refilling is the responsibility of the refiller. 

To triple rinse the containers before final disposal, empty the remaining contents from 

this container into application equipment or mix tank. Fill the container at least 10 

percent full with water. Agitate vigorously or recirculate water with the pump for 2 

minutes. Rinse all interior surfaces. Pour or pump rinsate into application equipment 

or rinsate collection system. Repeat this procedure two more times. 

Once container is rinsed, offer for recycling if available or puncture and dispose of in a 

sanitary landfill or by incineration. 

Text to Add to Directions for Use on Labels of Non-Seed Treatment Products in 

Refillable Containers , •• > , 

End users are authorized to remove tamper evident cables as required to remove' ltJt!, 

product from the container unless the container is equipped with one way valves and' 

refilling or retuming is planned. If this is the case, end users are noteuthcr;zed to • • • a ~. ~~~. 

remove tamper eVIdent cables, one way valves or clean contaIner. SftA9gntalne~u ~. 

Disposal instructions under Storage and Disposal. > ~ ~ > ,~ 

• '"~''' ,~ . • 
Attachment 2 

- Page 1 of 3- '-<' , " 

", , , C , , 

, , , " ( 

, , , , C , , 

Differences between statements provided in 40 CFR part 1,58 ~nd 'c 

PR Notice 2007-4, and Bes statements accepted by EPA as of N<)\ieinber :taOll r , , , , , , , ., t«'<e c 

.. 1) Identification of Container Types , < 

• 0 ~ ~ 

, c < , 

The federal regulations in §156.140(c) allow EPA to modify or waive the ' , < , 

requirements, or permit or require alternative labeling statements, for the 

"Identification of container types" statements that include recycling or reconditioning 

statements. 

BCS uses a statement other than the standard recycling or reconditioning 

statements provided in §156.140(a)(3) for nonrefillable containers for seed treatment 

products. BCS's instructions for seed treatment products in nonrefillable containers 

direct the user to return the container to BCS or offer it for recycling, dispose of in a 

sanitary landfill, or by incineration. 

2) Pressure-rinsing instructions for nonrefillable containers that are Bottom 

Discharge IBCs 

The BCS pressure-rinsing instructions are the same for seed and non-seed 

treatment products in rigid, nonrefillable Bottom Discharge IBCs containers that are 

too large to shake. 

BCS adds the statements for the "timing of the residue removal procedure" 

provided in §156.156 for refillable containers to the instructions for nonrefillable 

containers "before final disposal." Those statements are: "Pressure rinsing the 

container before final disposal is the responsibility of the person disposing of the 

container." The federal regulations in § t56.146(a) give options for instructions to 

clean/rinse nonrefillable containers promptly after emptying, rather than before final 

disposal. -

BCS may use pressure rinsing instructions for nonrefillable bottom discharge 

IBCs, rather than the triple rinsing instructions in §156.146(b). 

In addition, the BCS pressure rinsing instructions differ in the following ways from 

the options for instructions provided in §156.146(c) for nonrefillable, rigid containers 

of difutable pesticides that are too large to shake: 

Instead of holding the container upside down over application equipment or 

mix tank, users are instructed to "Raise the bottom of the IBC by 1.5 inches on the 

side which is opposite of the bottom discharge valve to promote more complete 

product removal." and to "Completely remove the top lid of the IBC." 

In the language provided in the EPA regulations, users are directed to rinse 

at about 40 PSI for at least 30 seconds and drain for 1 0 seconds after the flow 

begins to drip. Instead, the BCS language directs users to continuously pump or 

drain rinsate and to pressure rinse for 2 minutes until rinsate becomes clear. 

Because the BCS language instructs users to completely remove the top lid, 

the label also directs users to replace the lid and close the bottom valve. 

" '\ 

90

Attachment 2 

- Page 1 of 3- '-<' , " 

", , , C , , 

, , , , C , , 

Differences between statements provided in 40 CFR part 1,58 ~nd 'c 

PR Notice 2007-4, and Bes statements accepted by EPA as of N<)\ieinber :taOll r 

1) Identification of Container Types 

, , , , , , , .' t«'<e c 

.. , , " 

The federal regulations in §156.140(c) allow EPA to modify or waive the ' , < , 

requirements, or permit or require alternative labeling statements, for the 

"Identification of container types" statements that include recycling or reconditioning 

statements. 

BCS uses a statement other than the standard recycling or reconditioning 

statements provided in §156.140(a)(3) for nonrefillable containers for seed treatment 

products. BCS's instructions for seed treatment products in nonrefillable containers 

direct the user to return the container to BCS or offer it for recycling, dispose of in a 

sanitary landfill, or by incineration. 

2) Pressure-rinsing instructions for nonrefillable containers that are Bottom 

Discharge IBCs 

The BCS pressure-rinsing instructions are the same for seed and non-seed 

treatment products in rigid, nonrefillable Bottom Discharge IBCs containers that are 

too large to shake. 

BCS adds the statements for the "timing of the residue removal procedure" 

provided in §156.156 for refillable containers to the instructions for nonrefillable 

containers "before final disposal." Those statements are: "Pressure rinsing the 

container before final disposal is the responsibility of the person disposing of the 

container." The federal regulations in § t56.146(a) give options for instructions to 

clean/rinse nonrefillable containers promptly after emptying, rather than before final 

disposal. -

BCS may use pressure rinsing instructions for nonrefillable bottom discharge 

IBCs, rather than the triple rinsing instructions in §156.146(b), 

In addition, the BCS pressure rinsing instructions differ in the following ways from 

the options for instructions provided in §156.146(c) for nonrefillable, rigid containers 

of difutable pesticides that are too large to shake: 

Instead of holding the container upside down over application equipment or 

mix tank, users are instructed to "Raise the bottom of the IBC by 1.5 inches on the 

side which is opposite of the bottom discharge valve to promote more complete 

product removaL" and to "Completely remove the top lid of the IBC," 

In the language provided in the EPA regulations, users are directed to rinse 

at about 40 PSI for at least 30 seconds and drain for 1 0 seconds after the flow 

begins to drip. Instead, the BCS language directs users to continuously pump or 

drain rinsate and to pressure rinse for 2 minutes until rinsate becomes clear. 

Because the BCS language instructs users to completely remove the top lid, 

the label also directs users to replace the lid and close the bottom valve. 
Attachment 2 

-Page2of3-

Differences between statements provided in 40 CFR part 156 and 

PR Notice 2007~4, and BCS statements accepted by EPA as of November 2009 

(Note: The federal regulations in 156.146(c) have dffferent pressure~rinse 

instructions for nonrefillable containers of liquid and solid dilutable pesticides. 

BCS does not indicate whether its instructions would apply to liquid or solid 

dilutables, or both, aUhough these containers are generally designed to hold 

liquids. It is acceptable for BCS to use the same pressure rinsing instructions 

for containers of both liquid and solid dilutable pesticides.) 

3) Triple-rinsing instructions for Nonrefillable Containers that are Top 

Discharge IBCs, Drums and Kegs 

The BCS trjple~rinsing instructions are the same for both seed and non-seed 

treatment products in rigid, nonrefillable containers that are Top Discharge IBCs, 

Drums, and Kegs. Here is how those instructions differ from the options for 

instructions provided in §156.146(b)(3) for dilutable pesticides in nonrefJllable, rigid 

containers too large to shake: 

BCS adds the following statement for the "timing of the residue removal 

procedure" to the triple-rinsing instructions for nonrefillable containers: "Pressure 

rinsing [or Cleaning] the container before final disposal is the responsibility of the 

person disposing of the container." The federal regulations, on the other hand, give 

options for instructions to clean/rinse nonrefillable containers promptly after emptying 

[in §1S6.146(a)]. but not before final disposal. 

Instead of filling the container * full with water, recap and shake for 10 

seconds as provided in the federal regulations under §156.146(b), BCS instructs the 

user to fill the container at least 10% full with water. 

The BCS instructions do not include the sentence for nonrefillable 

containers too large to shake from §156.146(b){2)(3) "Replace and tighten closures." 

BCS uses the cleaning instructions from §156.156(b)(2)(iii) for refillable 

containers for the nonrefillable top discharge IBCs, drums and kegs with the addition 

of the statement "Rinse all interior surfaces". 

The BCS instructions to "Pour or pump rinsate into application equipment 

or rinsate collection system" differs slightly from the language in the regulations 

under §156.146(b), which says "Pour rinsate into application equipment or a mix tank 

or store rinsate for later use or disposal." 

4) Rinsing Instructions - Refillable Containers 

~. ) . The BCS pressure~rinsing instructions (for both seed and non~seed treatmentJ Z •• i> 

products) for refillable Bottom Discharge IBCs are the same as the instructions L.!SE!lj a • 

for nonrefillable bottom discharge IBCs, except that the instructions for refillable H ~ 

containers adds: "Cleaning before refilling is the responsibility of the fe/dEB." 1 . . ~ ~ ~.~. 

[ReqUIred In §156.156(a)]. 33~'n~ J U~~~ 

As discussed in section 3 above, the cleaning instructions for the to):1sHscharQ.9 • 

IBCs, drums and kegs are the same as the cleaning instructions from,) J' ; "~. ~ , , 

91

Attachment 2 

-Page2of3-

Differences between statements provided in 40 CFR part 156 and 

PR Notice 2007~4, and BCS statements accepted by EPA as of November 2009 

(Note: The federal regulations in 156.146(c) have dffferent pressure~rinse 

instructions for nonrefillable containers of liquid and solid dilutable pesticides. 

BCS does not indicate whether its instructions would apply to liquid or solid 

dilutables, or both, aUhough these containers are generally designed to hold 

liquids. It is acceptable for BCS to use the same pressure rinsing instructions 

for containers of both liquid and solid dilutable pesticides.) 

3) Triple-rinsing instructions for Nonrefillable Containers that are Top 

Discharge IBCs, Drums and Kegs 

The BCS trjple~rinsing instructions are the same for both seed and non-seed 

treatment products in rigid, nonrefillable containers that are Top Discharge IBCs, 

Drums, and Kegs. Here is how those instructions differ from the options for 

instructions provided in §156.146(b)(3) for dilutable pesticides in nonrefJllable, rigid 

containers too large to shake: 

BCS adds the following statement for the "timing of the residue removal 

procedure" to the triple-rinsing instructions for nonrefillable containers: "Pressure 

rinsing [or Cleaning] the container before final disposal is the responsibility of the 

person disposing of the container." The federal regulations, on the other hand, give 

options for instructions to clean/rinse nonrefillable containers promptly after emptying 

[in §1S6.146(a)]. but not before final disposal. 

Instead of filling the container * full with water, recap and shake for 10 

seconds as provided in the federal regulations under §156.146(b), BCS instructs the 

user to fill the container at least 10% full with water. 

The BCS instructions do not include the sentence for nonrefillable 

containers too large to shake from §156.146(b){2)(3) "Replace and tighten closures." 

BCS uses the cleaning instructions from §156.156(b)(2)(iii) for refillable 

containers for the nonrefillable top discharge IBCs, drums and kegs with the addition 

of the statement "Rinse all interior surfaces". 

The BCS instructions to "Pour or pump rinsate into application equipment 

or rinsate collection system" differs slightly from the language in the regulations 

under §156.146(b), which says "Pour rinsate into application equipment or a mix tank 

or store rinsate for later use or disposal." 

4) Rinsing Instructions - Refillable Containers 

~. ) . The BCS pressure~rinsing instructions (for both seed and non~seed treatmentJ Z •• i> 

products) for refillable Bottom Discharge IBCs are the same as the instructions L.!SE!lj a • 

for nonrefillable bottom discharge IBCs, except that the instructions for refillable H ~ 

containers adds: "Cleaning before refilling is the responsibility of the fe/dEB." 1 

. . ~ ~ ~.~. 

[ReqUIred In §156.156(a)]. 33~'n~ J U~~~ 

As discussed in section 3 above, the cleaning instructions for the to):1sHscharQ.9 • 

IBCs, drums and kegs are the same as the cleaning instructions from,) J' ; "~. ~ , , 
Attachment 2 

- Page 3 ot3 w n,I' , C"" ( 

" , - , '" f 

r , , , < c , 

, , , , Differences between statements provided in 40 CFR part 1))6 find '''' • 

PR Notice 2007·4, and BCS statements accepted by EPA as of W6vembera609 t ~ r f"Ct 

, " 

§156.156(b)(2)(iH) with the addition of the statement "Rinse all interforc SUrlaces" A~d. 

a change in the introduction from ''To clean the contaIner before final disposal .. ~'.tr.t <' 

''To triple rinse the container before final disposaL" (' , • , 

, , c ~ 

5) Other Changes to the Container Handling Instructions 

The BCS instructions for disposal of refillable containers for non-seed treatment 

groducts give users the option of contacting an agricultural retailer or BCS for 

container return, disposal and recycling information; in contrast, the instructions for 

disposal of refillable containers for seed treatment products instruct the user to 

contact BCS CUstomer Service Center. 

Although not required in §156.140(b), BCS adds a recycling or reconditioning 

statement tor refillable containers. 

In all cases, BCS uses the statement "Once container is rinsed, offer for recycling 

if available or puncture and dispose of in a sanitary landfill or by incinerations" for 

both nonrefillable and refillable containers of both seed and non-seed treatment 

products. BCS is voluntarily deleting all references to burning as suggested by EPA. 

6) Directions for Use 

Lastly, BCS adds text to the directions for use on the labels of seed and nonseed treatment products in refillable containers that allow the user to remove tamper 

evident cables unless the container has one-way valves and will be refilled or 

returned. 

(, -/ 

92

Attachment 2 

- Page 3 ot3 w 

, , , , 

r ( ( ( < C , , 

, , Differences between statements provided in 40 CFR part 1))6 find '''' • 

PR Notice 2007-4, and BCS statements accepted by EPA as of W6vembera609 t ~ r f"Ct 

, " 

§156.156(b)(2)(iH) with the addition of the statement "Rinse all interforc SUrlaces" A~d. 

a change in the introduction from ''To clean the contaIner before final disposal .. ~'.tr.t <' 

''To triple rinse the container before final disposaL" (' , • , 

( , C ~ 

5) Other Changes to the Container Handling Instructions 

The BCS instructions for disposal of refillable containers for non-seed treatment 

groducts give users the option of contacting an agricultural retailer or BCS for 

container return, disposal and recycling information; in contrast, the instructions for 

disposal of refillable containers for seed treatment products instruct the user to 

contact BCS CUstomer Service Center. 

Although not required in §156.140(b), BCS adds a recycling or reconditioning 

statement tor refillable containers. 

In all cases, BCS uses the statement "Once container is rinsed, offer for recycling 

if available or puncture and dispose of in a sanitary landfill or by incinerations" for 

both nonrefillable and refillable containers of both seed and non-seed treatment 

products. BCS is voluntarily deleting all references to burning as suggested by EPA. 

6) Directions for Use 

Lastly, BCS adds text to the directions for use on the labels of seed and nonseed treatment products in refillable containers that allow the user to remove tamper 

evident cables unless the container has one-way valves and will be refilled or 

returned.