### 1

**Appendix D. Citations Considered to be Part of the Data Base Supporting the Reregistration Eligibility Decision of Pyrethrins**  **MRID# Study**  42010901 Campbell, S.; Lynn, S. (1991) An Acute Oral Toxicity Study with Pyrethrum Extract in the Northern

Bobwhite Quail: Lab Project Number: 326 - 103. Unpublished study prepared by Wildlife International Ltd. 40 p. 

### 41968801 Grimes, J.; Lynn, S.; Smith, G. (1991) A Dietary LC50 Study with Pyrethrum Extract in the Northern

Bobwhite Quail: Lab Project Number: 326 - 101. Unpublished study prepared by Wildlife Inter - national Ltd. 62 p. 

### 41968802 Grimes, J.; Lynn, S.; Smith, G. (1991) A Dietary LC50 Study with Pyrethrum Extract in the Mallard: Lab

Project Number: 326/102. Unpublished study prepared by Wildlife International Ltd. 62 p. 

### 43082301 Machado, M. (1994) Pyrethrum Extract (FEK - 99): A Flow- Through Acute Toxicity Test with Bluegill

Sunfish (Lepomis macrochirus): Final Report: Lab Project Number: 93/8/4916. Unpublished study prepared by Springborn Laboratories, Inc. 66 p. 

### 43082302 Machado, M. (1994) Pyrenone Crop Spray (Sample Ref. 13650): A Flow- Through Acute Toxicity Test with

Bluegill Sunfish (Lepomis macrochirus): Final Report: Lab Report Number 93/11/5008. Unpublished study prepared by Springborn Laboratories, Inc. 66 p. 

### 43082303 Machado, M. (1994) Pyrethrum Extract (FEK - 99): A Flow- Through Acute Toxicity Test with Rainbow

Trout (Oncorhynchus mykiss): Final Report: Lab Project Number: 93/11/5084. Unpublished study prepared by Springborn Laboratories, Inc. 65 p. 

### 43082304 Machado, M. (1994) Pyrenone Crop Spray (Sample Ref. 13650): A Flow- Through Acute Toxicity Test with

Rainbow Trout (Oncorhynchus mykiss): Final Report: Lab Project Number: 93/11/5048. Unpublished study prepared by Springborn Laboratories, Inc. 65 p. 

### 43082305 Putt, A. (1994) Pyrethrum Extract (FEK- 99): A Acute Toxicity to Daphnids (Daphnia magna) under Flow Through Conditions: Final Report: Lab Project Number: 93/11/5082. Unpublished study prepared by Springborn Laboratories, Inc. 71 p 

### 43082 306 Putt, A. (1994) Pyrenone Crop Spray (Sample Ref. 13650): Acute Toxicity to Daphnids (Daphnia magna)

under Flow- Through Conditions: Final Report: Lab Project Number: 93/11/5075. Unpublished study prepared by Springborn Laboratories, Inc. 82 p. 

### 4308230 7 Machado, M. (1994) Pyrethrum Extract (FEK - 99): A Flow- Through Acute Toxicity Test with Sheepshead

Minnow (Cy prinodon variegatus): Final Report: Lab Project Number: 93/12/5081. Unpublished study prepared by Springborn Laboratories, Inc. 64 p. 

### 43082309 D ionne E. (1994) Pyrethrum Extract (FEK- 99): Acute Toxicity to Eastern Oyster (Crassostrea virginica)

under Flow- Through Conditions: Final Report: Lab Project Number: 93/11/5032. Unpublished study prepared by Springborn Laboratories, Inc. 65 p. 

### 43082311 M achado, M. (1994) Pyrethrum Extract (FEK - 99): Acute Toxicity to Mysid Shrimp (Mysidopsis bahia)

under Flow- Through Conditions: Final Report: Lab Project Number: 93/12/5097. Unpublished study prepared by Springborn Laboratories, Inc. 68 p. 

### 43082308 Machado, M. (1994) Pyrenone Crop Spray (Sample Ref. 13650): A Flow - Through Acute Toxicity Test with

Sheepshead Minnow (Cyprinodon variegatus): Final Report: Lab Project Number: 93/11/5037. Unpublished study prepared by Springborn Laboratories, Inc. 63 p. 

### 43082 310 Dionne E. (1994) Pyrenone Crop Spray (Sample Ref. 13650): Acute Toxicity to Eastern Oyster (Crassostrea

virginica) under Flow- Through Conditions: Final Report: Lab Project Number: 93/10/4995. Unpublished study prepared by Springborn Laboratories, Inc. 67 p. 

### 43082312 Machado, M. (1994) Pyrenone Crop Spray (Sample Ref. 13650): Acute Toxicity to Mysid Shrimp

(Mysidopsis bahia) under Flow - Through Conditions: Final Report: Lab Project Number: 93/12/5077. Unpublished study prepared by Springborn Laboratorie s, Inc. 67 p.

### 2

**MRID# Study**  43252701 Machado, M. (1994) Pyrethrum Extract (FEK - 99) - The Toxicity to Fathead Minnow (Pimephales promelas) During an Early Life - Stage Exposure: Final Report: Lab Project Number: 93 - 10 - 4983: 11572. 0193. 6114. 120. Unpublished study prepare d by Springborn Lab., Inc. 137 p. 

### 43252702 Putt, A. (1994) Pyrethrum Extract (FEK- 99) - The Chronic Toxicity to Daphnia magna Under Flow- Through

Conditions: Final Report: Lab Project Number: 94 - 1 - 5116: 11572.0193.6115.130. Unpublished study prepared by Springborn Lab., Inc. 165 p. 

### 42599501 Gabriel, D. (1992) Acute Oral Toxicity, LD50 -- Rats: Pyrethrum Extract: Lab Project Number: 92 - 7529A.

Unpublished study prepared by Biosearch Inc. 109 p. 

### 42008101 Gabriel, D. (1991) Acute Oral Toxicity LD50 -- Rats: Pyre thrum Extract: Lab Project Number: 91 - 7316A.

Unpublished study prepa - red by Biosearch Inc. 82 p. 

### 41964801 Gabriel, D. (1991) Pyrethrum Extract: Acute Dermal Toxicity, Single Level -- Rabbits: Lab Project Number:

91 - 7316A. Unpublished study prepared by Bio search Inc. 40 p. 

### 42008001 Hoffman, G. (1991) An Acute Inhalation Toxicity Study of Pyrethrum Extract in the Rat: Final Report: Lab

Project Number: 91 - 8331. Unpublished study prepared by Bio/dyanmics, Inc. 143 p. 

### 41964802 Bielucke, J. (1991) Pyrethrum Extract: Primary Eye Irritation-- Rabbits: Lab Project Number: 91 - 7316A.

Unpublished study prepared by Biosearch Inc. 30 p. 

### 41964803 Extract, P. (1991) Pyrethrum Extract: Primary Skin Irritation -- Rabbits: Lab Project Number: 91 - 7316A.

Unpublished study prepared by Biosearch Inc. 23 p. 

### 41964804 Romanelli, P. (1991) Pyrethrum Extract: Guinea Pig Dermal Sensitization -- Modified Buehler Method: Lab

Project Number: 91 - 7316A. Unpublished study prepared by Biosearch Inc. 61 p. 

### 42925801 Hermansky, S.; Hurley, J. (1993) Acute Oral Neurotoxicity Study with Pyrethrum Extract in Rats: Lab

Project Number: 92N1036. Unpublished study prepared by Union Carbide Chemicals and Plastics Co., Inc., Bushy Run Research Center. 393 p. 

### 42930401 Hermansky, S.; Hurley, J. (1993) P eroral (Gavage) Neurotoxicity Probe Study with Pyrethrum Extract in

CD Rats: Lab Project Number: 91N0122. Unpublished study prepared by Union Carbide, Bushy Run Research Center (BRRC). 84 p. 

### 43785301 Van Miller, J. (1995) Peroral (Gavage) Neurotoxicity Probe Study With Py rethrum Extract in CD Rats: Amended Report: Lab Project Number: 91N0122. Unpublished study prepared by Union Carbide (Bushy Run Research Center). 4 p. 

### 43785302 Van Miller, J. (1995) Acute Oral Neurotoxicity Study With Pyrethrum Extract in Rats: Amend ed Report:

Lab Project Number: 92N1036. Unpublished study prepared by Union Carbide (Bushy Run Research Center). 4 p. 

### 42212601 Goldenthal, E. (1992) 21 - Day Repeated Dose Dermal Toxicity Study with Pyrethrum Extract in Rabbits: Lab Project Number: 556 - 018. Unpublished study prepared by International Research and Development Corp. 247 p. 

### 42478201 Newton, P. (1992) A Subchronic (3 - Month) Inhalation Toxicity Study of Pyrethrum Extract in the Rat Via

Whole -body

Exposures: Final Report: Lab Project Number: 91 - 8 335. Unpublished study prepared by Bio/dynamics Inc. 870 p. 

### 42328701 Engel, R. (1992) Letter sent to Office of Pesticide Programs dated 5/26/92 concerning findings in a 90 - day

inhalation study with Pyrethrum Extract.Prepared by Chem. Specialties Manuf. Assoc. for Pyrethrin Joint Venture. 13 p. 

### 41559501 Goldenthal, E. (1990) Evaluation of Pyrethrum Extract in a Two Year Dietary Toxicity and Oncogenicity

Study in Rats: Lab Project No. 556 - 011. Unpublished study prepared by Internation - al Research and Development Corp. 2002 p.

### 3

**MRID# Study**  43811301 Schoenig, G. (1995) Addendum to the Response to EPA Data Evaluation Record for Study Entitled:

Evaluation of Pyrethrum Extract in a T wo - Year Dietary Toxicity and Oncogenicity Study in Rats: Lab Project Number: 556 - 011. Unpublished study prepared by International Research and Development Corp. 13 p. 

### 43567701 Schoenig, G. (1995) Response to EPA Data Evaluation Record for Study Entitled: Evaluation of Pyrethrum

Extract in a T wo - Year Dietary Toxicity and Oncogenicity Study in Rats: Lab Project Number: 56 - 011. Unpublished study prepared by International Research and Development Corp. 186 p. 

### 41496501 Goldenthal, E. (1990) Evaluation of Pyrethrum Extract in a One Year Chronic Toxicity Study in Dogs: Lab

Project Number: 556 - 007. Un- published study prepared by International Research and Develop - ment Corp. 331 p. 

### 46605701 Osimitz, T.; Droege, W. (2005) A Review of the Toxicoligical Significance of Cellular Changes in the

Larynx in the Rat: Pyrethrins. Unpublished study prepared by Science Strategies. 41 p. 

### 45889801 Finch, J.; Martin, T.; Travers, K.; et al. (2002) Pyrethrins: 28 Day Dose Range Finding Study in Female

Rats with Administration by the Diet: Lab Project Number: 19422: 455324. Unpublished study prepared by Inveresk Research Gro up. 105 p. 

### 45889802 Finch, J.; Martin, T.; Travers, K.; et al. (2002) Definitive Mechanistic Toxicity Study in Rats with

Py rethrins: Lab Project Number: 21029: 455790. Unpublished study prepared by Inveresk Research. 578 p. 

### 45889803 Lake, B. (2002) An Investigation of Some Hepatic Enzyme Activities in Liver Samples Derived from

Inveresk Study 455790: Definitive Mechanistic Toxicity Study in Rats with Pyrethrins: Final Report: Lab Project Number: 4024/2: 4024/2/2/2002. Unpublished study prepared by TNO BI BRA International Ltd. 214 p. 

### 45889804 Osimitz, T. (2002) Overview of Mode of Action Studies on Pyrethrins. Unpublished study prepared by

Py rethrin Joint Venture. 15 p. 

### 43811301 Schoenig, G. (1995) Addendum to the Response to EPA Data Evaluation Record f or Study Entitled: Evaluation of Pyrethrum Extract in a T wo - Year Dietary Toxicity and Oncogenicity Study in Rats: Lab Project Number: 556 - 011. Unpublished study prepared by International Research and Development Corp. 13 p. 

### 43567701 Schoenig, G. (1995) Re sponse to EPA Data Evaluation Record for Study Entitled: Evaluation of Pyrethrum

Extract in a T wo - Year Dietary Toxicity and Oncogenicity Study in Rats: Lab Project Number: 56 - 011. Unpublished study prepared by International Research and Development Corp. 1 86 p. 

### 41559501 Goldenthal, E. (1990) Evaluation of Pyrethrum Extract in a Two Year Dietary Toxicity and Oncogenicity

Study in Rats: Lab Project No. 556 - 011. Unpublished study prepared by Internation - al Research and Development Corp. 2002 p. 

### 44223501 Burin, G.; Harvey, P. (1997) Assessment of New Information Relevant to the Carcinogenic Potential of

Py rethrins. Unpublished study prepared by Technology Sciences Group, Inc. and AgrEvo UK Ltd. 141 p. 

### 44113001 Py

rethrin Joint Venture (1996) Response to June 12, 1995 EPA Carcinogenicity Peer Review Committee Revie w of

Py rethrins: Lab Project Number: PJV RESPONSE TO EPA: TO EPA - CPRC 6/12/95: 556 - 011. Unpublished study. 864 p. 

### 43889701 Harvey, P. (1995) Pyrethrum: Lung Tumor Rebuttal. Unpublished study prepared by Chemical Speciality

Manufacturers Assoc. 7 p. 

### 43585201 Goldenthal, E. (1988) Evaluation of Pyrethrum Extract in a 13 - Week Dose Range Finding Study (in Mice):

Lab Project Number: 556 - 008. Unpublished study prepared by International Research and Develop me nt Corp. 243 p.

### 4

**MRID# Study**  43567702 Schoenig, G. (1995) Response to EPA Data Evaluation Record for Study Entitled: Evaluation of Pyrethrum

Extract in an 18 Month Dietary Oncogenicity Study in Mice: Lab Project Number: 556 - 13. Unpublished study prepared by International Research and Development Corp. 40 p. 

### 41559401 Goldenthal, E. (1990) Evaluation of Pyrethrum Extract in an Eighteen Month Dietary Oncogenicity Study in

Mice: Lab Project Number 556 - 013. Unpublished study prepared by International Research & Developme nt Co. 1471 p. 

### 40288202 Schardein, J. (1987) Evaluation of Pyrethrum Extract in a Defini - tive Rat Teratology Study: Lab Project

ID: IRDC 556 - 002. Unpublished study prepared by International Research and Devel - opment Corp. 76 p. 

### 40603701 Schardein, J. ( 1987) Range - finding Teratology Study in Rats with Pyrethrum Extract: Laboratory Project ID

556 - 001. Unpublished study prepared by International Research and Development Corp. 41 p. 

### 40603702 Schardein, J. (1987) Range - finding Teratology Study in Rabbits with Py rethrum Extract: Laboratory Project ID 556 - 003. Unpublished study prepared by International Research and Development Corp. 43 p. 

### 40288203 Schardein, J. (1987) Evaluation of Pyrethrum Extract in a Definitive Rabbit Teratology Study: Lab Project

ID: 55 6 - 004. Unpub - lished study prepared by International Research and Development Corp. 78 p. 

### 41327501 Schardein, J. (1989) Two Generation Reproduction Study in Rats with Pyrethrum Extract: Lab Project

Number: 556/005. Unpub - lished study prepared by International Research and Development Corp. 547 p. 

### 41344701 San, R.; Springfield, K. (1989) Salmonella/Mammalian - microsome Plate Incorporation Mutagenicity Assay

(Ames Test) with a Confirmatory Assay: Lab Project Number: T8729.501014. Unpublish - ed study prepared by Microbiological Associates, Inc. 69 p. 

### 43987001 Curry, P. (1996) Chromosome Aberrations in Chinese Hamster Ovary (CHO) Cells: Pyrethrum Extract,

Blend FEK- 99: Final Report: Lab Project Number: G96AC14.330001: 8004. Unpublished study prepared by Microbiological Associates, Inc. 61 p. 

### 41344601 Putman, D.; Morris, M. (1989) Chromosome Abberations in Chinese Hamster Ovary (CHO) Cells:

Py rethrum Extract; Blend FEK- 99: Lab Project Number: T8729/337. Unpublished study prepared by Micro biological Associates Inc. 34 p. 

### 41344501 Curren, R. (1989) Unscheduled DNA Synthesis Assay in Rat Primary Hepatocytes with a Confirmatory

Assay: Pyrethrum Extract Blend FEK- 99: Final Report: Lab Project Number: T8729/380009. Unpub - lished study prepared by Microbiological Associates, Inc. 43 p. 

### 43566301 Limoges, Jeannine. (1994) Determination of the Metabolic Profile of 14C - Py rethrin 1 in Rats When Administered in Four Different Dosing Formulations" in support of the Study titled Pharmacokinetics and Metabolism of Pyrethrin I in the Rat. Unpublished study prepared by Biological Test Center. 136 p. 

### 43884101 Selim, S. (1995) Determination of Expired 14C O2 Following a Single Oral Dose of Pyrethrin I in the Rat ,

Biological Test Center. 

### 43554304 Selim, S. (1995) Pharmacokine tics and Metabolism of 14C Pyrethrin I in the Rat. BTC Study No.

P1092006. Unpublished study prepared by Biological Test Center. 496 p. 

### 43554305 Casida, J.; (1995) Opinion letter on PY 1 Metabolism in Rats. 

### 42846901 Dimmenna, G.; Schoenig, G. (1993) Revi ew of the Mammalian Metabolism of the Natural Pyrethrins. Unpublished study prepared by Toxicology/Regulatory Services, Inc. 39 p. 

### 42939601 Engel, R. (1993) Commentary on Agency Letter dated March 17, 1993: re: Review of General Metabolism Study. Unpubl ished study prepared by CSMA for the Pyrethrin Joint Venture. 11 p.

### 5

**MRID# Study**  41248801 Class, T.; Ando,T.; Casida, J. (1989) Pyrethroid Metabolism; Microsomal Oxidase Metabolites of (S) -

Bioallethrin and the Six Natural Pyrethrins. Project No. (none) Unpublished report prepared by Pesticide Chemistry and Toxicology Laboratory. 

### 41968803 Lynn, S.; Hoxter, K. (1991) An Acute Contact Toxicity Study with Pyrethrum Extract with the Honey Bee:

Lab Project No: 326/104. Unpublished study prepared by Wildlife International Ltd. 33 p. 

### 40700401 Reddy, G. (1988) Analytical Results of Pyrethrin Photolysis Resi - dues after Exposure to Natural Sunlight:

SL# 15981 - 15982. Un- published study prepared by Shrader Laboratories. 96 p. 

### 43567502 S elim, S. (1995) Hydrolysis of Pyrethrin 1 as a Function of pH at 25 (degrees) C: Amended Report: Lab

Project Numbers: P1092011: 93 - 1147.BTC. Unpublished study prepared by Biological Test Center. 163 p. 

### 43188201 Selim, S. (1994) Hydrolysis of Pyrethrin 1 as a Function of pH at 25 degrees C: Lab Project Number:

P1092011: 93 - 1147.BTC. Unpublished study prepared by Biological Test Center. 83 p. 

### 43567601 Schoenig, G. (1995) Response to EPA Data Evaluation Record for Study Entitled: Aqueous Photolysis of

Py rethrin 1: Lab Project Number: P1192006. Unpublished study prepared by Biological Test Center. 6 p. 

### 43096601 Selim, S. (1994) Aqueous Photolysis of Pyrethrin 1: Lab Project Number: P1192006. Unpublished study

prepared by Biological Test Center. 87 p. 

### 430 96602 Testman, R. (1994) Soil Surface Photolysis of Pyrethrin 1: Lab Project Number: P1192007. Unpublished

study prepared by Biological Test Center. 91 p. 

### 43499803 Robinson, R. (1994) Aerobic Soil Metabolism of (carbon 14)Pyrethrin 1: Lab Project Number: XBL93061:

RPT00204. Unpublished study prepared by Xenobiotic Lab., Inc. 170 p. 

### 43499801 Robinson, R.; Wisocky, M. (1994) Anaerobic Aquatic Metabolism of (carbon 14)Pyrethrin 1: Lab Project

Number: XBL93062: RPT00205. Unpublished study prepared by Xenobi otic Lab., Inc. 167 p. 

### 43499802 Robinson, R.; Wisocky, M. (1994) Aerobic Aquatic Metabolism of (carbon 14)Pyrethrin 1: Lab Project

Number: XBL93063: RPT00193. Unpublished study prepared by Xenobiotic Lab., Inc. 130 p. 

### 43096603 Reynolds, J.; Robinson, R . (1994) Adsorption and Desorption of (carbon 14) Pyrethrin 1 in Four Soils: Lab

Project Number: 93064: RPT00156. Unpublished study prepared by XenoBiotic Laboratories, Inc. 123 p. 

### 43096604 Selim, S. (1994) Laboratory Volatility of Pyrethrin 1 from Soil: Lab Project Number: P0693011.

Unpublished study prepared by Biological Test Center. 101 p. 

### 42745501 Hattermann, D. (1992) LX1180 - 02 (Pyrethrum + Piperonyl Butoxide) Field Dissipation - Terrestrial Study on

Bareground in California, Georgia, and Michigan: Lab Project Number: 91189: 18021E08. Unpublished study prepared by Bio/Dynamics, Inc. 207 p. 

### 43807101 Brookman, D.; Curry, K.; Smith, C. (1995) Data Waiver Request for the Requirement of a Study on

Terrestrial Field Dissipation for Degradates of Pyrethrin. Unpublished study prepared by Technology Sciences Group, Inc. 28 p. 

### 43818501 Brookman, D.; Curry, K.; Hobson, J.; et al. (1995) Data Waiver Request for the Requirement of a Study on

Aquatic Field Dissipation of Pyrethrin. Unpublished study prepared by T echnology Sciences Group, Inc. 34 p. 

### 43195201 Hattermann, D. (1994) Pyrethrin Analytical Phase for Pyrenone Crop Spray (Pyrethrin + Piperonyl

Butoxide) Aquatic Dissipation Study Applied Post- Emergence to Barewater in California, Arkansas, and Mississippi : Lab Project Number: 18021V09: 91190: BD - 047 - 92. Unpublished study prepared by Pharmaco LSR International, Inc. and Landis International, Inc. 152 p 

### 43302301 Schocken, M. (1994) Bioconcentration Study with (carbon 14) Pyrethrin 1 in Bluegill Sunfish: Final Report:

Lab Project Number: 94 - 5 - 5258: 11572.0993.6125.140. Unpublished study prepared by Springborn Labs., Inc. 148 p.

### 6

**MRID# Study**  43884102 St. Laurent, J. ( 1995) Development and Validation of an Analytical Methodology for the Determination of

Total Pyrethrins in Water, Acetone, and Fish Tissue: Final Report: Lab Project Number: 93 - 9 - 4922: 11572.0193.6105.250. Unpublished study prepared by Springborn Labs, Inc . 87 p. 

### 40700401 Reddy, G. (1988) Analytical Results of Pyrethrin Photolysis Resi - dues after Exposure to Natural Sunlight:

SL# 15981 - 15982. Un- published study prepared by Shrader Laboratories. 96 p. 

### 45900802 Singer, S.; Curry, K.; Brookman, D. (2003) Response to Chemistry and Exposure Branch Revie w Dated

May 20, 1999 Regarding the Nature of Pyrethrin (PY) Residues in Plants and Animals: Lab Project Number: 68 - D4 - 0010. Unpublished study prepared by Biological Test Center. 132 p. 

### 43668001 Selim, S. (19 95) Nature of (carbon 14) - Py rethrin 1 (PY 1) Residues in Leaf Lettuce: Amended Report: Lab Project Number: P0193016: 94 - 1215.BTC. Unpublished study prepared by Biological Test Center. 296 p. 

### 43628401 Selim, S. (1995) Nature of (Carbon - 14) Pyrethrin 1 (PY 1) Residues in Potato: Amended Report: Lab

Project Number: P0193017: 94 - 1167.BTC. Unpublished study prepared by Biological Test Center. 368 p. 

### 43628402 Selim, S. (1995) Nature of (Carbon - 14) Pyrethrin 1 (PY1) Residues in Tomato: Amended Report: Lab

Proj ect Number: P0193018: 94 - 1225.BTC. Unpublished study prepared by Biological Test Center. 360 p. 

### 43554301 Selim, S. (1995) Nature of the (carbon 14) - Py rethrin 1 (PY 1) Residues in Potato: Lab Project Number: P0193017: 94 - 1167.BTC. Unpublished study prepared by Biological Test Center. 155 p. 

### 43554302 Selim, S. (1995) Nature of the (carbon 14) - Py rethrin 1 (PY 1) Residues in Tomato: Lab Project Number: P0193018: 94 - 1225.BTC. Unpublished study prepared by Biological Test Center. 161 p. 

### 43554303 Selim, S. ( 1995) Nature of the (carbon 14) - Py rethrin 1 (PY 1) Residues in Leaf Lettuce: Lab Project Number: P0193016: 94 - 1215.BTC. Unpublished study prepared by Biological Test Center. 165 p. 

### 45900802 Singer, S.; Curry, K.; Brookman, D. (2003) Response to Chemistry and Exposure Branch Revie w Dated

May 20, 1999 Regarding the Nature of Pyrethrin (PY) Residues in Plants and Animals: Lab Project Number: 68 - D4 - 0010. Unpublished study prepared by Biological Test Center. 132 p. 

### 43837601 Selim, S. (1995) Metabolism Study of Py rethrin 1 in Lactating Goat Following Oral or Dermal Adminstration: (Amended Report): Lab Project Number: P0494014: 95 - 0380.BTC. Unpublished study prepared by Biological Test Center. 421 p. 

### 43837602 Selim, S. (1995) Metabolism Study of Pyrethrin 1 in Laying Hens Following Oral or Dermal

Administration: (Amended Report): Lab Project Number: P0494015: 95 - 0400.BTC. Unpublished study prepared by Biological Test Center. 396 p. 

### 43628301 Selim, S. (1995) Metabolism Study of Pyrethrin 1 in Lactating Goat F ollowing Oral or Dermal

Administration: Lab Project Number: P0494014: 95 - 0380.BTC. Unpublished study prepared by Biological Test Center. 413 p. 

### 43628302 Selim, S. (1995) Metabolism Study of Pyrethrin 1 in Laying Hens Following Oral or Dermal

Administrati on: Lab Project Number: P0494015: 95 - 0400.BTC. Unpublished study prepared by Biological Test Center. 387 p. 

### 43833403 Hatton, C.; Baker, F. (1995) Identification of ((carbon 14) - Acid) Pyrethrin I Metabolite in Goat Fat and Hen

Liver and Egg Yolk: Lab Proj ect Number: 555W: 555W - 1. Unpublished study prepared by PTRL West, Inc. 95 p. 

### PAM Vol II Res. analyt. method

### 7

**MRID# Study**  45256501 Hattermann, D. (2000) Amended Field and Processing Phases for LX1180 - 02 (Pyrethrin + Piperonyl

Butoxide) Processed Commodity Trial on P otatoes in Washington: Lab Project Number: 18008D022. Unpublished study prepared by Landis International, Inc. 220 p. 

### 45037102 Hatterman, D. (1999) Amended Pyrethrin Analytical Phase on the Raw Agricultural Commodity Residue

Evaluation of Pyrethrin + Pip eronyl Butoxide Applied as Pyrenone Crop Spray to Tomatoes: Lab Project Number: 18015B006: 1714 - 91 - 180 - 02 - 15B52. Unpublished study prepared by Landis International, Inc. and Agvise, Inc. 371 p. 

### 45037103 Hatterman, D. (1999) Amended Pyrethrin Analytical P hase on the Raw Agricultural Commodity Residue

Evaluation of Pyrethrin + Piperonyl Butoxide Applied as Pyrenone Crop Spray to Oranges: Lab Project Number: 18001B015: 1714 - 91 - 180 - 02 - 01B93: 93 - 0076. Unpublished study prepared by Landis International, Inc. and Agvise, Inc. 339 p. 

### 45037104 Hatterman, D. (1999) Amended Pyrethrin Analytical Phase on the Raw Agricultural Commodity Residue

Evaluation of Pyrethrin + Piperonyl Butoxide Applied as Pyrenone Crop Spray to Grapes: Lab Project Number: 18003B019: 1714 - 92 - 180 - 02 - 03B03: BD - 007 - 93. Unpublished study prepared by Landis International, Inc. and Agvise, Inc. 319 p. 

### 44140401 Winkler, D.; Huff, D. (1996) Magnitude of Residues in Meat and Milk from Lactating Dairy Cows Exposed

to Pyrethrum Extract: Addendum No. 1 to Amended Final Report: Lab Project Number: 94 - 0020. Unpublished study prepared by EN - CAS Analytical Labs. 54 p. 

### 44140402 Winkler, D.; Huff, D. (1995) Magnitude of Residues in Meat and Milk from Lactating Dairy Cows Exposed

to Pyrethrum Extract: Amende d Final Report: Lab Project Number: 94 - 0020: 890. Unpublished study prepared by EN - CAS Analytical Labs and PTRL East, Inc. 639 p. 

### 44126901 Hattermann, D. (1996) Amended Pyrethrin Analytical Phase on the Raw Agricultural Commodity Residue

Evaluation of Py

rethrin + Piperonyl Butoxide Applied as Pyrenone Crop Spray to Leafy Vegetables: Amended Final Report: (Includes "Field Phase for LX1180 - 02 (Pyrethrin + Piperonyl Butoxide) Raw Agricultural Commodity Trials on Leafy Vegetables in CA, FL, AZ, MI, CO, & TX") : Lab Project Number: 18009A003: 93 - 0064: BD - 007 - 93. Unpublished study prepared by Landis International, Inc.; EN - CAS Analytical Labs; and Pharmaco LSR International, Inc. 456 p. 

### 42009801 Meinen, V.; Bergman, J. (1991) Residue Study of Pyrethrins, Pipero nyl Butoxide, and MGK 264 in Certain

Food Commodities Resulting from Use as a Space in a Simulated Feed and Food Processing Situation: Lab Project Number: GLP - 078. Unpublished study prepared by MGK Co. 145 p. 

### 42009802 Meinen, V.; Bergman, J. (1991) Residue Study of Pyrethrins, Piperonyl Butoxide, and MGK 264 in Certain

Food Commodities Resulting from Use as a Contact Spray in a Simulated Feed and Food Processing Situation: Lab Project Number: GLP - 075. Unpublished study prepared by MGK Co. 146 p. 

### 4200980 3 Meinen, V. (1991) Residue Study of Pyrethrins, Piperonyl Butoxide, and MGK 264 in Certain Food

Commodities Resulting from Use as a Space Spray in a Warehouse Situation: Lab Project Number: GLP 077. Unpublished study prepared by MGK Co. 116 p. 

### 42009804 Meinen, V. (1991) Residue Study of Pyrethrins, Piperonyl Butoxide, and MGK 264 in Certain Food

Commodities Resulting from Use as a Contact Spray in a Warehouse Situation: Lab Project Number: GLP 076. Unpublished study prepared by MGK Co. 114 p. 

### 4200980 5 Meinen, V.; Bergman, J. (1991) Residue Study of Pyrethrins, Piperonyl Butoxide, and MGK 264 in Certain

Food Commodities and Surfaces Resulting From Use as an Intermediate Aerosol Spray in a Simulated Restaurant Situation: Lab Project Number: GLP - 193. Unp ublished study prepared by MGK Co. 199 p.

### 8

**MRID# Study**  43833401 Winkler, D.; Huff, D. (1995) Magnitude of Residues in Meat and Milk from Lactating Dairy Cows Exposed

to Pyrethrum Extract: Amended Final Report: Lab Project Number: 94 - 0020: 890. Unpublished study prepared by EN - CAS Analytical Labs and PTRL East, Inc. 639 p. 

### 43833402 Winkler, D.; Huff, D. (1995) Magnitude of Residues in Meat and Eggs from Laying Hens Exposed to

Py rethrum Extract: Amended Final Report: Lab Project Number: 94 - 0022: 891. Unpublished study prepared by EN - CAS Analytical Labs and PTRL East, Inc. 583 p. 

### 45900801 Singer, S.; Curry, K.; Brookman, D. (2003) Response to Chemistry and Exposure Branch Revie w Dated

March 19, 1999 Regarding Magnitude of Pyrethrin (PY) Residues in Plants: Lab Project Number: 68 - D4 - 0010: EL8228 - S1: ENC - 14/93. Unpublished study prepared by En - Cas Analytical Laboratories. 197 p. 

### 45037101 Hatterman, D. (1999) Amended Pyrethrin Analytical Phase on the Raw Agricultural Commodity Residue

Evaluation of Pyrethrin + Piperonyl Butoxide Applied as Pyrenone Crop Spray to Legumes: Lab Project Number: 1714 - 91 - 180 - 02 - 07G81: 1714 - 91 - 180 - 02 - 07D78: 1714 - 91 - 180 - 02 - 07E77. Unpublished study prepared by Landis International, Inc. and Agvise, Inc. 652 p. 

### 43470806 Hattermann, D. (1994) Pyrethrin Analytical Phase on the Raw Agricultural Commodity Residue Evaluation

of Pyrethrin Applied as Pyrenone Crop Spray to Legumes: Final Report: (Includes "Field Phase for LX1180 - 02 (Pyrethrin + Piperonyl Butoxide) Raw Agricultural Commodity Trial on Legumes FL, WI, ND, CO, CA, MN, TX, and WA"): Lab Project Number: 18007A012: 714 - 91 - 180 - 02 - 07E - 76: 714 - 91 - 180 - 02 - 07E - 77. Unpublished study prepared by Paragon Global Services; EN - CAS Analytical Labs; and Pharmaco LSR International Inc. 604 p. 

### 45037101 Hatterman, D. (1999) Amended Pyrethrin Analytical Phase on the Raw Agricultural Commodity Residue

Evaluation of Pyrethrin + Piperonyl Butoxide Applied as Pyrenone Crop Spray to Legumes: Lab Project Number: 1714 - 91 - 180 - 02 - 07G81: 1714 - 91 - 180 - 02 - 07D78: 1714 - 91 - 180 - 02 - 07E77. Unpublished study prepared by Landis International, Inc. and Agvise, Inc. 652 p. 

### 43470806 Hattermann, D. (1994) Pyrethrin Analytical Phase on the Raw Agricultural Commodity Residue Evaluation

of Pyrethrin Applied as Pyrenone Crop Spray to Legumes: Final Report: (Includes "Field Phase for LX1180 - 02 (Pyrethrin + Piperonyl Butoxide) Raw Agricultural Commodity Trial on Legumes FL, WI, ND, CO, CA, MN, TX, and WA"): Lab Project Number: 18007A012: 714 - 91 - 180 - 02 - 07E - 76: 714 - 91 - 180 - 02 - 07E - 77. Unpublishe d study prepared by Paragon Global Services; EN - CAS Analytical Labs; and Pharmaco LSR International Inc. 604 p. 

### 43470805 Hattermann, D. (1994) Pyrethrin Analytical Phase on the Raw Agricultural Commodity Residue Evaluation

of Pyrethrin Applied as Pyrenone Crop Spray to Root and Tuber Crops: Final Report: (Includes "Field Phase for LX1180 - 02 (Pyrethrin + Piperonyl Butoxide) Raw Agricultural Commodity Trial on Root and Tuber Crops in TX, FL, ID, CO, ME, ND, and MN"): Lab Project Number: 18008A001: 714 - 91 - 18 0 - 02 - 08F - 23: 714 - 91 - 180 - 02 - 08J - 24. Unpublished study prepared by Paragon Global Services; EN - CAS Analytical Labs; and Pharmaco LSR International Inc. 362 p. 

### 43370801 Hattermann, D. (1994) Volume I: Field Phase for LX1180 - 02 (Pyrethrin + Piperonyl Butoxid e) Raw

Agricultural Commodity Trials on Small Fruits in New York, Oregon, Michigan, North Carolina, Florida, and Massachusetts; Volume II: Pyrethrin Analytical Phase on the Raw Agricultural Commodity Residue Evaluation of Pyrethrin Applied as Pyrenone Crop Spray to Small Fruits: Final Report: Lab Project Number: 18003A020. Unpublished study prepared by Paragon Global Services, EN - CAS Analytical Lab., and Pharmaco LSR International Inc. 324 p.

### 9

**MRID# Study**  43370801 Hattermann, D. (1994) Volume I: Field Phase for LX1180 - 02 (Pyrethrin + Piperonyl Butoxide) Raw

Agricultural Commodity Trials on Small Fruits in New York, Oregon, Michigan, North Carolina, Florida, and Massachusetts; Volume II: Pyrethrin Analytical Phase on the Raw Agricultural Commodity Residue Evaluation of Py

rethrin Applied as Pyrenone Crop Spray to Small Fruits: Final Report: Lab Project Number: 18003A020. Unpublished study prepared by Paragon Global Services, EN - CAS Analytical Lab., and Pharmaco LSR International Inc. 324 p. 

### 45398401 Hatterman, D. (2001) Field Phase for LX1180 - 02 (Pyrethrin + Piperonyl Butoxide) Raw Agricultural

Commodity Trials on Brassica in Arkansas, California, Oregon, New York, Florida, Texas and Georgia: Amended Final Report: Lab Project Number: 18014A004: 1714 - 91 - 180 - 02 - 14D - 37/AR. Unpublished study prepared by Landis International, Inc. 503 p. 

### 43292701 Hattermann, D. (1994) Pyrethrin Analytical Phase on the Raw Agricultural Commodity residue evaluation

of Pyrethrin + Piperonyl Butoxide Applied as Pyrenone Crop Spray to Brassica, including Field Phase for LX1180 - 20: Final Report: Lab Project Number: 18014A004. Unpublished study prepared by En- CAS Analytical Lab., Pharmaco LSR International Inc. 472 p. 

### 43470805 Hattermann, D. (1994) Pyrethrin Analytical Phase on the Raw Agricultural Commodity Residue Evaluation

of Pyrethrin Applied as Pyrenone Crop Spray to Root and Tuber Crops: Final Report: (Includes "Field Phase for LX1180 - 02 (Pyrethrin + Piperonyl Butoxide) Raw Agricultural Commodity Trial on Root and Tuber Crops in TX, FL, ID, CO, ME, ND, and MN"): Lab Project Number: 18008A001: 714 - 91 - 180 - 02 - 08F - 23: 714 - 91 - 180 - 02 - 08J - 24. Unpublished study prepared by Paragon Global Services; EN - CAS Analytical Labs; and Pharmaco LSR International Inc. 362 p. 

### 44126901 Hattermann, D. (1996) Amen ded Pyrethrin Analytical Phase on the Raw Agricultural Commodity Residue

Evaluation of Pyrethrin + Piperonyl Butoxide Applied as Pyrenone Crop Spray to Leafy Vegetables: Amended Final Report: (Includes "Field Phase for LX1180 - 02 (Pyrethrin + Piperonyl Buto xide) Raw Agricultural Commodity Trials on Leafy Vegetables in CA, FL, AZ, MI, CO, & TX"): Lab Project Number: 18009A003: 93 - 0064: BD - 007 - 93. Unpublished study prepared by Landis International, Inc.; EN - CAS Analytical Labs; and Pharmaco LSR International, Inc. 456 p. 

### 43232801 Hattermann, D. (1994) Pyrethrin Analytical Phase on the Raw Agricultural Commodity Residue Evaluation

of Pyrethrin & Piperonyl Butoxide Applied as Pyrenone Crop Spray to Leafy Vegetables (Also Field Phase for Raw Agricultural Commodity Trials on Leafy Vegetables): Lab Project Number: 18009A003. Unpublished study prepared by EN - CAS Analytical Labs. and PHARMACO LSR International Inc. 423 p. 

### 43910601 Hattermann, D. (1996) Amended Pyrethrin Analytical Phase on the Raw Agricultural Commodity Residue

Evaluation of Pyrethrin + Piperonyl Butoxide Applied as Pyrenone Crop Spray to Leafy Vegetables: Amended Final Report: (Includes "Field Phase for LX1180 - 02 (Pyrethrin + Piperonyl Butoxide) Raw Agricultural Commodity Trials on Leafy Vegetables in CA, FL, AZ, MI, CO, & TX"): Lab Project Number: 18009A003: 93 - 0064: BD - 007 - 93. Unpublished study prepared by Landis International, Inc.; EN - CAS Analytical Labs; and Pharmaco LSR International, Inc. 456 p. 

### 43370801 Hattermann, D. (1994) Volume I: Fiel d Phase for LX1180 - 02 (Pyrethrin + Piperonyl Butoxide) Raw

Agricultural Commodity Trials on Small Fruits in New York, Oregon, Michigan, North Carolina, Florida, and Massachusetts; Volume II: Pyrethrin Analytical Phase on the Raw Agricultural Commodity Resi due Evaluation of Pyrethrin Applied as Pyrenone Crop Spray to Small Fruits: Final Report: Lab Project Number: 18003A020. Unpublished study prepared by Paragon Global Services, EN - CAS Analytical Lab., and Pharmaco LSR International Inc. 324 p.

### 10

**MRID# Study**  45048001 Hatterman, D. (1997) Field Phase for LX1180 - 02 (Pyrethrin + Piperonyl Butoxide) Raw Agricultural

Commodity Trials on Cucurbits in Michigan, North Carolina, Arizona, California, Florida, Texas, New Jersey and Georgia: Amended Final Report: Lab Project Number: 18013A007: 1714 - 91 - 180 - 02 - 13B - 5: 714 - 91 - 180 - 02 - 13B - 54. Unpublished study prepared by Landis International, Inc. 111 p. 

### 43248701 Hattermann, D. (1994) Field Phase for LX1180 - 02 (Pyrethrin + Piperonyl Butoxide) Raw Agricultural

Commodity Trials on Cucurbi ts in Michigan, North Carolina, Arizona, California, Florida, Texas, New Jersey and Georgia: Pyrethrin Analytical Phase on the Raw Agricultural Commodity Residue Evaluation of Py rethrin + Piperonyl Butoxide Applied as Pyrenone Crop Spray to Cucurbits: Final Report: Lab Project Number: 18013A007. Unpublished study prepared by Paragon Global Services. 379 p. 

### 43440002 Hattermann, D. (1994) Pyrethrin Analytical Phase on the Raw Agricultural Commodity Residue Evaluation

of Pyrethrin Applied as Pyrenone Crop Sp ray to Citrus Crops: (Including Field and Processing Phases for LX1180 - 02 (Pyrethrin + Piperonyl Butoxide) Raw Agricultural Commodity Trials on Citrus in FL, CA, TX, and AZ): Lab Project Numbers: 18001A014: BD - 007 - 93: 93 - 0075. Unpublished study prepared by Paragon Global Services. 310 p. 

### 43370801 Hattermann, D. (1994) Volume I: Field Phase for LX1180 - 02 (Pyrethrin + Piperonyl Butoxide) Raw

Agricultural Commodity Trials on Small Fruits in New York, Oregon, Michigan, North Carolina, Florida, and Massachusetts; Volume II: Pyrethrin Analytical Phase on the Raw Agricultural Commodity Residue Evaluation of Pyrethrin Applied as Pyrenone Crop Spray to Small Fruits: Final Report: Lab Project Number: 18003A020. Unpublished study prepared by Paragon Global Services, EN - CAS Analytical Lab., and Pharmaco LSR International Inc. 324 p. 

### 43440002 Hattermann, D. (1994) Pyrethrin Analytical Phase on the Raw Agricultural Commodity Residue Evaluation

of Pyrethrin Applied as Pyrenone Crop Spray to Citrus Crops: (Including Fiel d and Processing Phases for LX1180 - 02 (Pyrethrin + Piperonyl Butoxide) Raw Agricultural Commodity Trials on Citrus in FL, CA, TX, and AZ): Lab Project Numbers: 18001A014: BD - 007 - 93: 93 - 0075. Unpublished study prepared by Paragon Global Services. 310 p. 

### 4 4126901 Hattermann, D. (1996) Amended Pyrethrin Analytical Phase on the Raw Agricultural Commodity Residue

Evaluation of Pyrethrin + Piperonyl Butoxide Applied as Pyrenone Crop Spray to Leafy Vegetables: Amended Final Report: (Includes "Field Phase for LX1 180 - 02 (Pyrethrin + Piperonyl Butoxide) Raw Agricultural Commodity Trials on Leafy Vegetables in CA, FL, AZ, MI, CO, & TX"): Lab Project Number: 18009A003: 93 - 0064: BD - 007 - 93. Unpublished study prepared by Landis International, Inc.; EN - CAS Analytical Labs ; and Pharmaco LSR International, Inc. 456 p. 

### 43232801 Hattermann, D. (1994) Pyrethrin Analytical Phase for Pyrenone Crop Spray (Pyrethrin + Piperonyl

Butoxide) Aquatic Dissipation Study Applied Post- Emergence to Barewater in California, Arkansas, and Mi ssissippi: Lab Project Number: 18021V09: 91190: BD - 047 - 92. Unpublished study prepared by Pharmaco LSR International, Inc. and Landis International, Inc. 152 p 

### 43910601 Hattermann, D. (1996) Amended Pyrethrin Analytical Phase on the Raw Agricultural Commo dity Residue

Evaluation of Pyrethrin + Piperonyl Butoxide Applied as Pyrenone Crop Spray to Leafy Vegetables: Amended Final Report: (Includes "Field Phase for LX1180 - 02 (Pyrethrin + Piperonyl Butoxide) Raw Agricultural Commodity Trials on Leafy Vegetables in CA, FL, AZ, MI, CO, & TX"): Lab Project Number: 18009A003: 93 - 0064: BD - 007 - 93. Unpublished study prepared by Landis International, Inc.; EN - CAS Analytical Labs; and Pharmaco LSR International, Inc. 456 p.

### 11

**MRID# Study**  44126901 Hattermann, D. (1996) Amended Pyrethrin Analytical Phase on the Raw Agricultural Commodity Residue

Evaluation of Pyrethrin + Piperonyl Butoxide Applied as Pyrenone Crop Spray to Leafy Vegetables: Amended Final Report: (Includes "Field Phase for LX1180 - 02 (Pyrethrin + Piperonyl Butoxide) Raw A gricultural Commodity Trials on Leafy Vegetables in CA, FL, AZ, MI, CO, & TX"): Lab Project Number: 18009A003: 93 - 0064: BD - 007 - 93. Unpublished study prepared by Landis International, Inc.; EN - CAS Analytical Labs; and Pharmaco LSR International, Inc. 456 p. 

### 43232801 Hattermann, D. (1994) Pyrethrin Analytical Phase for Pyrenone Crop Spray (Pyrethrin + Piperonyl

Butoxide) Aquatic Dissipation Study Applied Post- Emergence to Barewater in California, Arkansas, and Mississippi: Lab Project Number: 18021V09: 9119 0: BD - 047 - 92. Unpublished study prepared by Pharmaco LSR International, Inc. and Landis International, Inc. 152 p 

### 43910601 Hattermann, D. (1996) Amended Pyrethrin Analytical Phase on the Raw Agricultural Commodity Residue

Evaluation of Pyrethrin + Pipero nyl Butoxide Applied as Pyrenone Crop Spray to Leafy Vegetables: Amended Final Report: (Includes "Field Phase for LX1180 - 02 (Pyrethrin + Piperonyl Butoxide) Raw Agricultural Commodity Trials on Leafy Vegetables in CA, FL, AZ, MI, CO, & TX"): Lab Project Numb er: 18009A003: 93 - 0064: BD - 007 - 93. Unpublished study prepared by Landis International, Inc.; EN - CAS Analytical Labs; and Pharmaco LSR International, Inc. 456 p. 

### 45048001 Hatterman, D. (1997) Field Phase for LX1180 - 02 (Pyrethrin + Piperonyl Butoxide) Raw Agricultural

Commodity Trials on Cucurbits in Michigan, North Carolina, Arizona, California, Florida, Texas, New Jersey and Georgia: Amended Final Report: Lab Project Number: 18013A007: 1714 - 91 - 180 - 02 - 13B - 5: 714 - 91 - 180 - 02 - 13B - 54. Unpublished study prepared by Landis International, Inc. 111 p. 

### 43248701 Hattermann, D. (1994) Field Phase for LX1180 - 02 (Pyrethrin + Piperonyl Butoxide) Raw Agricultural

Commodity Trials on Cucurbits in Michigan, North Carolina, Arizona, California, Florida, Texas, New Jersey and Georgia: Pyrethrin Analytical Phase on the Raw Agricultural Commodity Residue Evaluation of Py rethrin + Piperonyl Butoxide Applied as Pyrenone Crop Spray to Cucurbits: Final Report: Lab Project Number: 18013A007. Unpublished study prepared by Paragon G lobal Services. 379 p. 

### 43248701 Hattermann, D. (1994) Pyrethrin Analytical Phase on the Raw Agricultural Commodity residue evaluation

of Pyrethrin + Piperonyl Butoxide Applied as Pyrenone Crop Spray to Brassica, including Field Phase for LX1180 - 20: Final Report: Lab Project Number: 18014A004. Unpublished study prepared by En - CAS Analytical Lab., Pharmaco LSR International Inc. 472 p. 

### 43292701 Hattermann, D. (1994) Pyrethrin Analytical Phase on the Raw Agricultural Commodity residue evaluation

of Pyrethrin + Piperonyl Butoxide Applied as Pyrenone Crop Spray to Brassica, including Field Phase for LX1180 - 20: Final Report: Lab Project Number: 18014A004. Unpublished study prepared by En- CAS Analytical Lab., Pharmaco LSR International Inc. 472 p. 

### 43440002 Hattermann, D. (1994) Pyrethrin Analytical Phase on the Raw Agricultural Commodity Residue Evaluation

of Pyrethrin Applied as Pyrenone Crop Spray to Citrus Crops: (Including Field and Processing Phases for LX1180 - 02 (Pyrethrin + Piperonyl Butoxide) Raw Agricultural Commodity Trials on Citrus in FL, CA, TX, and AZ): Lab Project Numbers: 18001A014: BD - 007 - 93: 93 - 0075. Unpublished study prepared by Paragon Global Services. 310 p.

### 12

**MRID# Study**  45037101 Hatterman, D. (1999) Amended Pyrethrin Analytical Phase on the Raw Agricultural Commodity Residue

Evaluation of Pyrethrin + Piperonyl Butoxide Applied as Pyrenone Crop Spray to Legumes: Lab Project Number: 1714 - 91 - 180 - 02 - 07G81: 1714 - 91 - 180 - 02 - 07D78: 1714 - 91 - 180 - 02 - 07E77. Unpublished study prepared by Landis International, Inc. and Agvise, Inc. 652 p. 

### 43470806 Hattermann, D. (1994) Pyrethrin Analytical Phase on the Raw Agricultural Commodity Residue Evaluation

of Pyrethrin Applied as Pyrenone Crop Spray to Legumes: Final Report: (Includes "Field Phase for LX1180 - 02 (Pyrethrin + Piperonyl Butoxide) Raw Agricultural Commodity Trial on Legumes FL, WI, ND, CO, CA, MN, TX, and WA"): Lab Project Number: 18007A012: 714 - 91 - 180 - 02 - 07E - 76: 714 - 91 - 180 - 02 - 07E - 77. Unpublished study prepared by Paragon Global Services; EN - CAS Analytical Labs ; and Pharmaco LSR International Inc. 604 p. 

### 45037101 Hatterman, D. (1999) Amended Pyrethrin Analytical Phase on the Raw Agricultural Commodity Residue

Evaluation of Pyrethrin + Piperonyl Butoxide Applied as Pyrenone Crop Spray to Legumes: Lab Project Numb er: 1714 - 91 - 180 - 02 - 07G81: 1714 - 91 - 180 - 02 - 07D78: 1714 - 91 - 180 - 02 - 07E77. Unpublished study prepared by Landis International, Inc. and Agvise, Inc. 652 p. 

### 43470806 Hattermann, D. (1994) Pyrethrin Analytical Phase on the Raw Agricultural Commodity Residue Evaluation

of Pyrethrin Applied as Pyrenone Crop Spray to Legumes: Final Report: (Includes "Field Phase for LX1180 - 02 (Pyrethrin + Piperonyl Butoxide) Raw Agricultural Commodity Trial on Legumes FL, WI, ND, CO, CA, MN, TX, and WA"): Lab Project Number: 1800 7A012: 714 - 91 - 180 - 02 - 07E - 76: 714 - 91 - 180 - 02 - 07E - 77. Unpublished study prepared by Paragon Global Services; EN - CAS Analytical Labs; and Pharmaco LSR International Inc. 604 p. 

### 43298901 Hattermann, D. (1994) Field Phase for LX1180 - 02 (Pyrethrin + Piperonyl B utoxide) Raw Agricultural

Commodity Trials on Fruiting Vegetable in Florida, Michigan, New Jersey, North Carolina, California, and Texas: Final Report: including Analytical Phase: Lab Project Number: 18015A005. Unpublished study prepared by Paragon Global Services, En - Cas Analytical Labs, and Pharmaco LSR International Inc. 272 p. 

### 43470805 Hattermann, D. (1994) Pyrethrin Analytical Phase on the Raw Agricultural Commodity Residue Evaluation

of Pyrethrin Applied as Pyrenone Crop Spray to Root and Tuber Crop s: Final Report: (Includes "Field Phase for LX1180 - 02 (Pyrethrin + Piperonyl Butoxide) Raw Agricultural Commodity Trial on Root and Tuber Crops in TX, FL, ID, CO, ME, ND, and MN"): Lab Project Number: 18008A001: 714 - 91 - 180 - 02 - 08F - 23: 714 - 91 - 180 - 02 - 08J - 24. Unpublished study prepared by Paragon Global Services; EN - CAS Analytical Labs; and Pharmaco LSR International Inc. 362 p. 

### 43470805 Hattermann, D. (1994) Pyrethrin Analytical Phase on the Raw Agricultural Commodity Residue Evaluation

of Pyrethrin Applied as Pyrenone Crop Spray to Root and Tuber Crops: Final Report: (Includes "Field Phase for LX1180 - 02 (Pyrethrin + Piperonyl Butoxide) Raw Agricultural Commodity Trial on Root and Tuber Crops in TX, FL, ID, CO, ME, ND, and MN"): Lab Project Number: 18008A001: 714 - 91 - 180 - 02 - 08F - 23: 714 - 91 - 180 - 02 - 08J - 24. Unpublished study prepared by Paragon Global Services; EN - CAS Analytical Labs; and Pharmaco LSR International Inc. 362 p. 

### 44126901 Hattermann, D. (1996) Amended Pyrethrin Analytical Phase on the Raw Agricultural Commodity Residue

Evaluation of Pyrethrin + Piperonyl Butoxide Applied as Pyrenone Crop Spray to Leafy Vegetables: Amended Final Report: (Includes "Field Phase for LX1180 - 02 (Pyrethrin + Piperonyl Butoxide) Raw Agricultural Commodity Trials on Leafy Veg etables in CA, FL, AZ, MI, CO, & TX"): Lab Project Number: 18009A003: 93 - 0064: BD - 007 - 93. Unpublished study prepared by Landis International, Inc.; EN - CAS Analytical Labs; and Pharmaco LSR International, Inc. 456 p.

### 13

**MRID# Study**  43232801 Hattermann, D. (1994) Pyrethrin Analytical Phase on the Raw Agricultural Commodity Residue Evaluation

of Pyrethrin & Piperonyl Butoxide Applied as Pyrenone Crop Spray to Leafy Vegetables (Also Field Phase for Raw Agricultural Commodity Trials on Leafy Vegetables): Lab Project Number: 18009A003. Unpublished study prepared by EN - CAS Analytical Labs. and PHARMACO LSR International Inc. 423 p. 

### 45048001 Hatterman, D. (1997) Field Phase for LX1180 - 02 (Pyrethrin + Piperonyl Butoxide) Raw Agricultural

Commodity Trials on Cucurbits in Michigan, North Carolina, Arizona, California, Florida, Texas, New Jersey and Georgia: Amended Final Report: Lab Project Number: 18013A007: 1714 - 91 - 180 - 02 - 13B - 5: 714 - 91 - 180 - 02 - 13B - 54. Unpublished study prepared by Landis International, Inc. 111 p. 

### 43248701 Hattermann, D. (1994) Field Phase for LX1180 - 02 (Pyrethrin + Piperonyl Butoxide) Raw Agricultural

Commodity Trials on Cucurbits in Michigan, North Carolina, Arizona, California, Florida, Texas, New Jersey and Georgia: Pyrethrin Analytical Phase on the Raw Agri cultural Commodity Residue Evaluation of Py rethrin + Piperonyl Butoxide Applied as Pyrenone Crop Spray to Cucurbits: Final Report: Lab Project Number: 18013A007. Unpublished study prepared by Paragon Global Services. 379 p. 

### 43370801 Hattermann, D. (1994) Volume I: Field Phase for LX1180 - 02 (Pyrethrin + Piperonyl Butoxide) Raw

Agricultural Commodity Trials on Small Fruits in New York, Oregon, Michigan, North Carolina, Florida, and Massachusetts; Volume II: Pyrethrin Analytical Phase on the Raw Agricultural Commodity Residue Evaluation of Pyrethrin Applied as Pyrenone Crop Spray to Small Fruits: Final Report: Lab Project Number: 18003A020. Unpublished study prepared by Paragon Global Services, EN - CAS Analytical Lab., and Pharmaco LSR International Inc. 324 p . 

### 43298901 Hattermann, D. (1994) Field Phase for LX1180 - 02 (Pyrethrin + Piperonyl Butoxide) Raw Agricultural

Commodity Trials on Fruiting Vegetable in Florida, Michigan, New Jersey, North Carolina, California, and Texas: Final Report: including Analytical Phase: Lab Project Number: 18015A005. Unpublished study prepared by Paragon Global Services, En - Cas Analytical Labs, and Pharmaco LSR International Inc. 272 p. 

### 47225601 Hattermann, D. (2007) Raw Agricultural Commodity (RAC) Residue Decline of Pyrethrin s/Piperonyl Butoxide Applied to Tomatoes. Project Number: 18015A023, 060230. Unpublished study prepared by Landis International, Inc. 248 p. 

### 47225602 Hattermann, D. (2007) Raw Agricultural Commodity (RAC) Residue Decline of Pyrethrins/Pipero nyl Butoxide Applied to Lettuce. Project Number: 18009A024, 060231. Unpublished study prepared by Landis International, Inc. 262 p. 

### 47225603 Hattermann, D. (2007) Raw Agricultural Commodity (RAC) Residue Decline of Pyrethrins/Piperonyl Buto xide Applied to Peaches. Project Number: 18002A025, 060232. Unpublished study prepared by Landis International, Inc. 258 p. 

### 47225604 Hattermann, D. (2007) Raw Agricultural Commodity (RAC) Residue Decline of Pyrethrins/Piperonyl Butoxide App lied to Blueberry. Project Number: 18003A026, 060233. Unpublished study prepared by Landis International, Inc. 281 p. 

### 45900801 Singer, S.; Curry, K.; Brookman, D. (2003) Response to Chemistry and Exposure Branch Revie w Dated

March 19, 1999 Re garding Magnitude of Pyrethrin (PY) Residues in Plants: Lab Project Number: 68 - D4 - 0010: EL8228 - S1: ENC - 14/93. Unpublished study prepared by En - Cas Analytical Laboratories. 197 p.

### 14

**MRID# Study**  43470803 Hattermann, D. (1994) Pyrethrin Analytical Phase on the Processed Commodity Residue Evaluation of

Py rethrin Applied as Pyrenone Crop Spray to Succulent Beans: Final Report: (Includes "Field and Processing Phases for LX1180 - 02 (Pyrethrin + Piperonyl Butoxide) Processed Commodity Trial on Succulent Beans in NY"): Lab Proje ct Number: 18007E013: 714 - 91 - 180 - 02 - 07E - 83. Unpublished study prepared by Paragon Global Services; EN - CAS Analytical Labs; and Pharmaco LSR International Inc. 185 p. 

### 43470804 Hattermann, D. (1994) Pyrethrin Analytical Phase on the Processed Commodity Res idue Evaluation of

Py rethrin Applied as Pyrenone Crop Spray to Root and Tuber Crops: Final Report: (Includes "Field and Processing Phases for LX1180 - 02 (Pyrethrin + Piperonyl Butoxide) Processed Commodity Trial on Potatoes and Sugarbeets in WA and CA"): Lab Project Number: 18008A002: 714 - 91 - 180 - 02 - 08B - 29: 714 - 91 - 180 - 02 - 08D - 21. Unpublished study prepared by Paragon Global Services; EN - CAS Analytical Labs; and Pharmaco LSR International Inc. 350 p. 

### 43470802 Hattermann, D. (1994) Pyrethrin Analytical Phase o n the Processed Commodity Residue Evaluation of

Py rethrin Applied as Pyrenone Crop Spray to Oranges: Final Report: (Includes "Field and Processing Phases for LX1180 - 02 (Pyrethrin + Piperonyl Butoxide) Processed Commodity Trial on Oranges in FL"): Lab Proje ct Number: 18001B015: 714 - 91 - 180 - 02 - 01B - 93. Unpublished study prepared by Paragon Global Services; EN - CAS Analytical Labs; and Pharmaco LSR International Inc. 272 p. 

### 43440001 Hattermann, D. (1994) Pyrethrin Analytical Phase on the Processed Commodity Res idue Evaluation of

Py rethrin Applied as Pyrenone Crop Spray to Grape: (including Field and Processing Phases for LX1180 - 02 (Py rethrin + Piperonyl Butoxide) Processed Commodity Trial on Grape in California): Lab Project Number: 18003B019: 93 - 0074: 1714 - 92 - 1 80 - 02 - 03B - 03. Unpublished study prepared by Paragon Global Services. 295 p. 

### 43470804 Hattermann, D. (1994) Pyrethrin Analytical Phase on the Processed Commodity Residue Evaluation of

Py rethrin Applied as Pyrenone Crop Spray to Root and Tuber Crops: Final Report: (Includes "Field and Processing Phases for LX1180 - 02 (Pyrethrin + Piperonyl Butoxide) Processed Commodity Trial on Potatoes and Sugarbeets in WA and CA"): Lab Project Number: 18008A002: 714 - 91 - 180 - 02 - 08B - 29: 714 - 91 - 180 - 02 - 08D - 21. Unpublished study prepared by Paragon Global Services; EN - CAS Analytical Labs; and Pharmaco LSR International Inc. 350 p. 43910601 Hattermann, D. (1996) Pyrethrin Analytical Phase on the Processed Commodity Residue Evaluation of

Py rethrins + Piperonyl Butoxide Applied as Py renone Crop Spray to Root and Tuber Crops: (Includes "Field and Processing Phases for LX1180 - 02 (Pyrethrin + Piperonyl Butoxide) Processed Commodity Trial on Potatoes in Washington"): Amended Final Report: Lab Project Number: 1714 - 95 - 180 - 02 - 08D - 03: 95 - 0 013 - 2: 18008D022. Unpublished study prepared by Landis International, Inc. and EN - CAS Analytical Labs. 249 p. 

### 43470801 Hattermann, D. (1994) Pyrethrin Analytical Phase on the Processed Commodity Residue Evaluation of

Py rethrin Applied as Pyrenone Crop Spray to Tomato: Final Report: (Includes "Field and Processing Phases for LX1180 - 02 (Pyrethrin + Piperonyl Butoxide) Processed Commodity Trial on Tomato in CA"): Lab Project Number: 18015B006: 714 - 91 - 180 - 02 - 15B - 52. Unpublished study prepared by Paragon Global Services; EN - CAS Analytical Labs; and Pharmaco LSR International Inc. 306 p. 

### 44460801 Maciver, D.; Keane, P.; Jones, D.; et al. (1997) Pyrethrins and Piperonyl Butoxide as Public Health

Insecticides. Unpublished study prepared by Pyrethrin Joint Venture and Piperonyl Butoxide Task Force. 35 p. 

### 45284601 Solecki, R. (2000) 1999 JMPR Monograph Addendum for Pyrethrin Extracts (Pyrethrins). Unpublished

study prepared by Bundesinstitut fur gesundheitlichen Verbraucherschutz und Veterinardmedizin. 22 p.

### 15

**MRID# Study**  45921601 Technology Sciences Group (2003) Pyrethrin Joint Venture Compilation of Use Information. Unpublished

study prepared by Consumer Specialty Products Association. 65 p. 

### 46027301 Pegus Research, Inc. (2001) Human Exposures to Consumer Products Containing Pyrethrins and

Py rethroids: Reports to the American Association of Poison Control Centers: 1994 - 1999. Unpublished study. 38 p. 

### 46261001 Cathcart, C. (2004) Evaluation of the Safety of Synergized Pyrethrins Formulations. Unpublished study

prepared by Science Strategies LLC. 19 p. 

### 46694801 Osimitz, T.; Sommers, N.; Kingston, R. (2005) Human Exposures to Products Containing Pyrethrins and

Piperonyl Butoxide: Analysis of Poison Control Center Data (2001 - 2003). Unpublished study prepared by Science Strategies. 28 p. 

### 46757301 Osimitz, T.; Franzosa, J.; Maciver, D.; et. al. (2006) Pyrethrins Allergic Contact Dermatitis in Man - An

Evidence - Based Dermatologic Review. Unpublished study prepared by Science Strategies and University of California. 35 p. 

### 46792702 Bretzl aff, R.; Sielken, R. (2006) Analysis of Pyrethrin - Induced Changes in Female Sprague - Dawley Rat

Liver. Unpublished study prepared by Sielken, Inc. 57 p. 

### 46792703 Lake, B. (20 06) An Investigation of the Effects of Pyrethrins on Some Cytochrome P450 Forms in Cultured

Rat and Human Hepatocytes. Project Number: 4024/4, 4024/4/2/2006. Unpublished study prepared by Py rethrin Joint Venture. 88 p. 

### 46792704 Klaunig, J. (2006) E xamination of Mode of Action of Pyrethrins Tumorigenesis in Mammals. Unpublished

study prepared by Indiana University School of Medicine. 42 p. 

### 46864601 Osimitz, T.; Franzosa, J. (2006) Pyrethrins and Respiratory Reactions - A Critical Review. Unpublished

study prepared by Science Strategies. 20 p. 

### 47036701 Lake, B. (2006) An Investigation of the Effects of Pyrethrins on some Rat Hepatic Peroxisomal Enzyme

Activities. Project Number: 4024/5, 4024/5/2/2006. Unpublished study prepared by Pyrethrin Joint Venture. 40 p. 

### 47241701 Osimitz, T.; Lake, B. (2007) Mode of Action Analysis for Rodent Liver Tumors Produced by Pyrethrins.

Unpublished study prepared by Science Strategies, LLC and Leatherhead Food International. 59 p. 

### 47464001 O'Shaughnessy, D.; Osimitz, T. (2008) Waiver Reques t - Regarding Requirement for Developmental

Neurotoxicity Study for Pyrethrins. Unpublished study prepared by Science Strategies and DOC Consulting . 8 p. 

### 47464002 O'Shaughnessy, D. (2008) Re - evaluation of Microscopic Patho logy in Nervous System Tissues from Bushy

Run Research Center Study 92N1036 (Acute Oral Neurotoxicity of Pyrethrum Extract in Rats). Unpublished study prepared by DOC, Inc. 7 p. 

### 47588101 Sharp, J.; Thom, E.; Carlson, D.; et. al.; (2008) Pyrethrins Joint Venture Proposal to Fulfill Reregistration

Requirements for Crop Pre - Harvest Residue: Response to EPA'S Review of Pyrethrins Studies on Tomatoes, Lettuce, Peaches, and Blueberries - EPA Letter Dated August 22, 2008. Unpublished study prepared by Consumer Specialty Products Association, Inc. (CSPA). 26 p.