Page 1 of 1INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form.Use additional sheet(s) if necessary.1. Company Name and Address4. EPA ProductRegistrationOMB Approval 2070-0107OMB Approval 2070-0057United States Environmental ProtectionAgency Washington, D.C. 20460DATA CALL-IN RESPONSE3. Date and Type of DCI and NumberPRODUCT SPECIFIC24-Feb-2010ID # PDCI-075202-292242. Case # and Name3132 Sodium fluorideChemical # and Name075202Sodium fluoride5. I wish tocancel thisproduct registration voluntarily6. Generic Data7. Product Specific Data7a. My product is an MUP andI agree to satisfy the MUPrequirements on the attachedform entitled "RequirementsStatus and Registrant'sResponse."7b. My product is an EUP andI agree to satisfy the EUPrequirements on the attachedform entitled "RequirementsStatus and Registrant'sResponse."6a. I am claiming a GenericData Exemption because Iobtain the active ingredientfrom the source EPA registration number listed below.6b. I agree to satisfy GenericData requirements as indicatedon the attached form entitled"Requirements Status andRegistrant's Response."N.A.N.A.10. Name of Company11. Phone Number9. Date8. Certification I certify that the statements made on this form and all attachments are true, accurate, and complete. I acknowledge that anyknowingly false or misleading statement may be punishable by fine, imprisonment or both under applicable law.Signature and Title of Company's Authorized Representative__________________________________INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form.Use additional sheet(s) if necessary.4. GuidelineRequirementNumber5. Study Title1. Company Name and AddressPage 1 of 4OMB Approval 2070-0107OMB Approval 2070-0057United States Environmental ProtectionAgency Washington, D.C. 20460REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE3. Date and Type of DCI and NumberID #PRODUCT SPECIFIC24-Feb-2010PDCI-075202-292242. Case # and Name3132 Sodium fluorideEPA Reg. No. 3008-588. TimeFrame(Months)9. RegistrantResponse7. TestSubstance6. UsePatternPROTOCOLProgressReports321Product Chemistry Data Requirements (Antimicrobial)(48)830.15508EPBBProduct Identity and composition(49)830.16008EPBBDescription of materials used to produce the product(50)830.16208EPBBDescription of production process(51)830.16508EPBBDescription of formulation process(52)830.16708EP & possibly TGAIBBDiscussion of formation of impurities(1 ,2 ,53)830.17008EP & possibly TGAIBBPreliminary analysis(54)830.17508EPBBCertified limits(55)830.18008EPBBEnforcement analytical method(3)830.63028TGAIBBColor(4)830.63038TGAI & EPBBPhysical state(5)830.63048TGAIBBOdor12. Name of Company13. Phone NumberSignature and Title of Company's Authorized Representative__________________________________10. Certification I certify that the statements made on this form and all attachments are true, accurate, and complete. Iacknowledge that anyknowingly false or misleading statement may be punishable by fine, imprisonment or both under applicable law11. DateINSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form.Use additional sheet(s) if necessary.4. GuidelineRequirementNumber5. Study Title1. Company Name and AddressPage 2 of 4OMB Approval 2070-0107OMB Approval 2070-0057United States Environmental ProtectionAgency Washington, D.C. 20460REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE3. Date and Type of DCI and NumberID #PRODUCT SPECIFIC24-Feb-2010PDCI-075202-292242. Case # and Name3132 Sodium fluorideEPA Reg. No. 3008-588. TimeFrame(Months)9. RegistrantResponse7. TestSubstance6. UsePatternPROTOCOLProgressReports321(6 ,7 ,56)830.63138TGAIBBStability to sunlight, normal and elevatedtemperatures, metals, and metal ions(8)830.63148EPBBOxidizing or reducing action(9)830.63158EPBBFlammability(10)830.63168EPBBExplodability(57)830.631716EPBBStorage stability of product(11)830.63198EPBBMiscibility(44)830.632016EPBBCorrosion characteristics(12)830.63218EPBBDielectric breakdown voltage(13 ,14)830.70008TGAI & EPBBpH of water solutions or suspensions830.70508TGAIBBUV/Visible absorption(15)830.71008EPBBViscosity(16 ,17)830.72008TGAI or PAIBBMelting point/melting rangeInitial to indicate certification as to information on this page (fulltext of certification is on page one).DateINSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form.Use additional sheet(s) if necessary.4. GuidelineRequirementNumber5. Study Title1. Company Name and AddressPage 3 of 4OMB Approval 2070-0107OMB Approval 2070-0057United States Environmental ProtectionAgency Washington, D.C. 20460REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE3. Date and Type of DCI and NumberID #PRODUCT SPECIFIC24-Feb-2010PDCI-075202-292242. Case # and Name3132 Sodium fluorideEPA Reg. No. 3008-588. TimeFrame(Months)9. RegistrantResponse7. TestSubstance6. UsePatternPROTOCOLProgressReports321(18 ,19)830.72208TGAI or PAIBBBoiling point/boiling range(20 ,21)830.73008TGAI & EPBBDensity/relative density(22 ,23)830.73708TGAI or PAIBBDissociation constant in water(24)830.75508TGAI or PAIBBPartition coefficient (n-octanol/water), shake flaskmethod(25)830.75708TGAI or PAIBBPartition coefficient (n-octanol/water), estimation byliquid chromatography(26)830.78408TGAI or PAIBBWater solubility: Column elution method, shake flaskmethod(27)830.78608TGAI or PAIBBWater solubility, generator column method(28 ,29)830.79508TGAI or PAIBBVapor pressureToxicology Data Requirements (Antimicrobial)(41 ,42 ,43)870.11008EP; MP; TGAIBBAcute Oral Toxicity (do not select)(30 ,31 ,32,45)870.12008EP; MP; TGAIBBAcute dermal toxicity(37 ,38 ,39,40)870.13008EP; MP; TGAI/EPBBAcute inhalation toxicityInitial to indicate certification as to information on this page (fulltext of certification is on page one).DateINSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form.Use additional sheet(s) if necessary.4. GuidelineRequirementNumber5. Study Title1. Company Name and AddressPage 4 of 4OMB Approval 2070-0107OMB Approval 2070-0057United States Environmental ProtectionAgency Washington, D.C. 20460REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE3. Date and Type of DCI and NumberID #PRODUCT SPECIFIC24-Feb-2010PDCI-075202-292242. Case # and Name3132 Sodium fluorideEPA Reg. No. 3008-588. TimeFrame(Months)9. RegistrantResponse7. TestSubstance6. UsePatternPROTOCOLProgressReports321(33 ,34 ,35,36)870.25008EP; MP; TGAI/EP; TGAIBBAcute dermal irritation(46 ,47)870.26008EP; MP; TGAIBBSkin sensitization870.24008BBAcute eye irritationInitial to indicate certification as to information on this page (fulltext of certification is on page one).DateCase # and Name:3132 Sodium fluorideDCI Number:PDCI-075202-29224Page 1 of 5[The following notes are referenced in column two (5. Study File) of the REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE form.]Footnotes:Key:United States Environmental ProtectionAgency Washington, D.C. 20460FOOTNOTES AND KEY DEFINITIONS FOR GUIDELINE REQUIREMENTSTGAI & EP = Technical Grade of the Active Ingredient and End-Use Product; EP; MP; TGAI = End Use Product; Manufacturing Use Product; Technical Grade Active Ingredient; TGAI or PAI =Technical Grade of the Active Ingredient or Pure Active Ingredient; EP = End Use Product [EP]; TGAI = Technical Grade Active Ingredient [TGAI]; EP; TGAI = End Use Product; Technical GradeActive Ingredient; EP & possibly TGAI = End- Use Product and possibly Technical Grade Active IngredientUse Categories Key:BB - Wood preservatives1Required for TGAIs and products produced by an integrated system.2If the TGAI cannot be isolated, data are required on the practical equivalent of the TGAI (i.e., if the active ingredient is either an acid, base or ionic form, and it is formulated into salts or esters,the concentration of the active ingredient in these products must be expressed in acid equivalent or active equivalent).3If the TGAI cannot be isolated, data are required on the practical equivalent of the TGAI (i.e., if the active ingredient is either an acid, base or ionic form, and it is formulated into salts or esters,the concentration of the active ingredient in these products must be expressed in acid equivalent or active equivalent).4If the TGAI cannot be isolated, data are required on the practical equivalent of the TGAI (i.e., if the active ingredient is either an acid, base or ionic form, and it is formulated into salts or esters,the concentration of the active ingredient in these products must be expressed in acid equivalent or active equivalent).5If the TGAI cannot be isolated, data are required on the practical equivalent of the TGAI (i.e., if the active ingredient is either an acid, base or ionic form, and it is formulated into salts or esters,the concentration of the active ingredient in these products must be expressed in acid equivalent or active equivalent).6If the TGAI cannot be isolated, data are required on the practical equivalent of the TGAI (i.e., if the active ingredient is either an acid, base or ionic form, and it is formulated into salts or esters,the concentration of the active ingredient in these products must be expressed in acid equivalent or active equivalent).7Data on the stability to metals and metal ions is required only if the active ingredient is expected to come in contact with either material during storage.8Required if the product contains an oxidizing or reducing agent9Required when the product contains combustible liquids.10Required when the product is potentially explosive.11Required if the product is an emulsifiable liquid and is to be diluted with petroleum solvents.12Required if the end-use product is a liquid and is to be used around electrical equipment.13If the TGAI cannot be isolated, data are required on the practical equivalent of the TGAI (i.e., if the active ingredient is either an acid, base or ionic form, and it is formulated into salts or esters,the concentration of the active ingredient in these products must be expressed in acid equivalent or active equivalent).14Required if the product is dispersible with water.15Required if the product is a liquid.Case # and Name:3132 Sodium fluorideDCI Number:PDCI-075202-29224Page 2 of 5[The following notes are referenced in column two (5. Study File) of the REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE form.]Footnotes:Key:United States Environmental ProtectionAgency Washington, D.C. 20460FOOTNOTES AND KEY DEFINITIONS FOR GUIDELINE REQUIREMENTSTGAI & EP = Technical Grade of the Active Ingredient and End-Use Product; EP; MP; TGAI = End Use Product; Manufacturing Use Product; Technical Grade Active Ingredient; TGAI or PAI =Technical Grade of the Active Ingredient or Pure Active Ingredient; EP = End Use Product [EP]; TGAI = Technical Grade Active Ingredient [TGAI]; EP; TGAI = End Use Product; Technical GradeActive Ingredient; EP & possibly TGAI = End- Use Product and possibly Technical Grade Active Ingredient16If the TGAI cannot be isolated, data are required on the practical equivalent of the TGAI (i.e., if the active ingredient is either an acid, base or ionic form, and it is formulated into salts or esters,the concentration of the active ingredient in these products must be expressed in acid equivalent or active equivalent).17Required when the TGAI is solid at room temperature.18If the TGAI cannot be isolated, data are required on the practical equivalent of the TGAI (i.e., if the active ingredient is either an acid, base or ionic form, and it is formulated into salts or esters,the concentration of the active ingredient in these products must be expressed in acid equivalent or active equivalent).19Required if the TGAI is liquid at room temperature.20If the TGAI cannot be isolated, data are required on the practical equivalent of the TGAI (i.e., if the active ingredient is either an acid, base or ionic form, and it is formulated into salts or esters,the concentration of the active ingredient in these products must be expressed in acid equivalent or active equivalent).21True density or specific density are required for all test substances. Data on bulk density is required for MPs that are solidat room temperature.22If the TGAI cannot be isolated, data are required on the practical equivalent of the TGAI (i.e., if the active ingredient is either an acid, base or ionic form, and it is formulated into salts or esters,the concentration of the active ingredient in these products must be expressed in acid equivalent or active equivalent).23Required when the test substance contains an acid or base functionality (organic or inorganic) or an alcoholic functionality (organic).24Required if the TGAI or PAI is organic and non-polar.25Required if the TGAI or PAI is organic and non-polar.26If the TGAI cannot be isolated, data are required on the practical equivalent of the TGAI (i.e., if the active ingredient is either an acid, base or ionic form, and it is formulated into salts or esters,the concentration of the active ingredient in these products must be expressed in acid equivalent or active equivalent).27If the TGAI cannot be isolated, data are required on the practical equivalent of the TGAI (i.e., if the active ingredient is either an acid, base or ionic form, and it is formulated into salts or esters,the concentration of the active ingredient in these products must be expressed in acid equivalent or active equivalent).28If the TGAI cannot be isolated, data are required on the practical equivalent of the TGAI (i.e., if the active ingredient is either an acid, base or ionic form, and it is formulated into salts or esters,the concentration of the active ingredient in these products must be expressed in acid equivalent or active equivalent).29Not required for salts.30Not required if test material is a gas or highly volatile.Case # and Name:3132 Sodium fluorideDCI Number:PDCI-075202-29224Page 3 of 5[The following notes are referenced in column two (5. Study File) of the REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE form.]Footnotes:Key:United States Environmental ProtectionAgency Washington, D.C. 20460FOOTNOTES AND KEY DEFINITIONS FOR GUIDELINE REQUIREMENTSTGAI & EP = Technical Grade of the Active Ingredient and End-Use Product; EP; MP; TGAI = End Use Product; Manufacturing Use Product; Technical Grade Active Ingredient; TGAI or PAI =Technical Grade of the Active Ingredient or Pure Active Ingredient; EP = End Use Product [EP]; TGAI = Technical Grade Active Ingredient [TGAI]; EP; TGAI = End Use Product; Technical GradeActive Ingredient; EP & possibly TGAI = End- Use Product and possibly Technical Grade Active Ingredient31For the six acute studies conducted with the end-use product, the test must be conducted using the product as formulated for sale and distribution. If the product is intended and labeled to bediluted for use, the applicant may also wish to conduct certain studies using the highest diluted concentration (i.e. lowest dilution rate) permitted by the labeling.32Not required if test material is corrosive to skin or has pH < 2 or >11.5; such a product will be classified as Toxicity Category I on the basis of potential dermal toxicity.33Not required if test material is a gas or highly volatile.34For the six acute studies conducted with the end-use product, the test must be conducted using the product as formulated for sale and distribution. If the product is intended and labeled to bediluted for use, the applicant may also wish to conduct certain studies using the highest diluted concentration (i.e. lowest dilution rate) permitted by the labeling.35Not required if test material is corrosive to skin or has pH < 2 or > 11.5; such a product will be classified as Toxicity Category I on the basis of potential eye irritation effects.36Required if intended use of the antimicrobial pesticide product will involve purposeful application on human skin or will result in comparable exposure to the product (e.g. uses in swimming poolwater), or if the active ingredient of the product is known or expected to be metabolized differently by the dermal route of exposure than by the oral route, and a metabolite of the active ingredientis the toxic moiety. The EP shall also be tested if any component of the EP may increase dermal absorption of the active ingredient(s) or potentiate toxic or pharmacologic effects.37For the six acute studies conducted with the end-use product, the test must be conducted using the product as formulated for sale and distribution. If the product is intended and labeled to bediluted for use, the applicant may also wish to conduct certain studies using the highest diluted concentration (i.e. lowest dilution rate) permitted by the labeling.38Required when the product consists of, or under conditions of use will result in, an inhalable material (e.g., gas, vapor, aerosol or particulates).39The 870 series studies for the MP and EP are intended to provide data on the acute toxicity of the product. Waivers for any orall of these studies may be granted when the applicant candemonstrate that the combination of inert ingredients is not likely to pose any significant human health risks. Where appropriate, the limit dose approach to testing is recommended.40Required when the product consists of, or under conditions of use will result in, an inhalable material (e.g. gas, volatile substances, or aerosol particulate).41Not required if test material is a gas or highly volatile.42For the six acute studies conducted with the end-use product, the test must be conducted using the product as formulated for sale and distribution. If the product is intended and labeled to bediluted for use, the applicant may also wish to conduct certain studies using the highest diluted concentration (i.e. lowest dilution rate) permitted by the labeling.43Diluted EP testing is required to support the end product registration if results using the EP meet the criteria for restricted use classification under 40 CFR Part 152.170(b) or special reviewconsideration under 40 CFR Part 154.7(a)(1).Case # and Name:3132 Sodium fluorideDCI Number:PDCI-075202-29224Page 4 of 5[The following notes are referenced in column two (5. Study File) of the REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE form.]Footnotes:Key:United States Environmental ProtectionAgency Washington, D.C. 20460FOOTNOTES AND KEY DEFINITIONS FOR GUIDELINE REQUIREMENTSTGAI & EP = Technical Grade of the Active Ingredient and End-Use Product; EP; MP; TGAI = End Use Product; Manufacturing Use Product; Technical Grade Active Ingredient; TGAI or PAI =Technical Grade of the Active Ingredient or Pure Active Ingredient; EP = End Use Product [EP]; TGAI = Technical Grade Active Ingredient [TGAI]; EP; TGAI = End Use Product; Technical GradeActive Ingredient; EP & possibly TGAI = End- Use Product and possibly Technical Grade Active Ingredient44The 16-month deadline for submission of this study applies if you are conducting a new study for submission to the Agency to satisfy this requirement. In such case, you are required to submit aprogress report to the Agency within 3 months following the deadline for submission of the 90-Day response required for this PDCI. Further information concerning the development of dataappears on page 7 of the Generic and Product Specific Data Call-In Notice. If you intend to submit an existing study that hasnot been submitted previously to the Agency or to cite previouslysubmitted data, the existing study or citation to the previously submitted study must be submitted along with your 90-Day Response to this PDCI. If the Agency determines that such existingdata are not adequate, you will need to develop and submit new data within the stated deadline.45Diluted EP testing is required to support the end product registration if results using the EP meet the criteria for restricted use classification under 40 CFR Part 152.170(b) or special reviewconsideration under 40 CFR Part 154.7(a)(1).46For the six acute studies conducted with the end-use product, the test must be conducted using the product as formulated for sale and distribution. If the product is intended and labeled to bediluted for use, the applicant may also wish to conduct certain studies using the highest diluted concentration (i.e. lowest dilution rate) permitted by the labeling.47Required if repeated dermal exposure is likely to occur under conditions of use.48Data must be provided in accordance with 40 CFR Part 158.320.49Data must be provided in accordance with 40 CFR Part 158.325.50Data must be provided in accordance with 40 CFR Part 158.330.51Data must be provided in accordance with 40 CFR Part 158.335.52Data must be provided in accordance with 40 CFR Part 158.340.53Data must be provided in accordance with 40 CFR Part 158.345.54Data must be provided in accordance with 40 CFR Part 158.350.55Data must be provided in accordance with 40 CFR Part 158.355.56Data on stability of the MP and TGAI to storage at normal temperatures are required. Data on the stability of the TGAI to hightemperatures are required if the TGAI is expected to be subjectedto temperatures >50 degrees Celsius (122 degrees Fahrenheit) during production or storage.Case # and Name:3132 Sodium fluorideDCI Number:PDCI-075202-29224Page 5 of 5[The following notes are referenced in column two (5. Study File) of the REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE form.]Footnotes:Key:United States Environmental ProtectionAgency Washington, D.C. 20460FOOTNOTES AND KEY DEFINITIONS FOR GUIDELINE REQUIREMENTSTGAI & EP = Technical Grade of the Active Ingredient and End-Use Product; EP; MP; TGAI = End Use Product; Manufacturing Use Product; Technical Grade Active Ingredient; TGAI or PAI =Technical Grade of the Active Ingredient or Pure Active Ingredient; EP = End Use Product [EP]; TGAI = Technical Grade Active Ingredient [TGAI]; EP; TGAI = End Use Product; Technical GradeActive Ingredient; EP & possibly TGAI = End- Use Product and possibly Technical Grade Active Ingredient57The 16-month deadline for submission of this study applies if you are conducting a new study for submission to the Agency to satisfy this requirement. In such case, you are required to submit aprogress report to the Agency within 3 months following the deadline for submission of the 90-Day response required for thisPDCI. Further information concerning the development of dataappears on page 7 of the Generic and Product Specific Data Call-In Notice. If you intend to submit an existing study that hasnot been submitted previously to the Agency or to cite previouslysubmitted data, the existing study or citation to the previously submitted study must be submitted along with your 90-Day Response to this PDCI. If the Agency determines that such existingdata are not adequate, you will need to develop and submit new data within the stated deadline.United States Environmental ProtectionAgency Washington, D.C. 20460LIST OF ALL REGISTRANTS SENT THIS DATA CALL-IN NOTICECo. Nr.Company NameAgent ForAddressCity & StateZipCase # and Name:3132,Sodium fluoridePRESCHEM PTY. LTDSCIREG, INC.12733 DIRECTOR'S LOOPWOODBRIDGEVA2219283933OSMOSE INC.980 ELLICOTT STBUFFALONY142093008OSMOSE UTILITIES SERVICES,INC.980 ELLICOTT STREETBUFFALONY1420975341