Exhibit 10.03


 





CONFIDENTIAL
TREATMENT REQUESTED. CERTAIN PORTIONS OF THIS DOCUMENT HAVE BEEN OMITTED PURSUANT TO A REQUEST FOR CONFIDENTIAL TREATMENT AND,
WHERE APPLICABLE, HAVE BEEN MARKED WITH AN ASTERISK TO DENOTE WHERE OMISSIONS HAVE BEEN MADE. THE CONFIDENTIAL MATERIAL HAS BEEN
FILED SEPARATELY WITH THE SECURITIES AND EXCHANGE COMMISSION










 


CONFIDENTIAL







Amended & Restated IP License Agreement



 


 


 


This Amended & Restated IP License
Agreement (the “License Agreement”) is made and entered into effective as of July 19, 2016 (the “Effective
Date”) by and between Amyris, Inc., a Delaware corporation, having its place of business at 5885 Hollis Street,
Suite 100, Emeryville, California 94608 (“Amyris”) and Novvi LLC, a Delaware limited liability corporation,
having its place of business at 5885 Hollis Street, Suite 100, Emeryville, California 94608 (“Novvi LLC”). Amyris
and Novvi LLC are sometimes referred to herein individually as a “Party” and collectively as the “Parties.”


 


WHEREAS, Amyris
and Cosan US, Inc. formed Novvi LLC on September 6, 2011, with each owning fifty percent (50%) of the membership units of
Novvi LLC, to operate a joint venture involving the development, production, marketing and sale of Base Oils (as defined
below), Additives (as defined below), and Lubricants (as defined below) for use in the Lubricants Markets (as defined below);


 


WHEREAS, on
March 26, 2013, Amyris and Cosan US executed an Amended and Restated Operating Agreement for Novvi LLC (“Amended and Restated
Operating Agreement”) to memorialize their respective initial capital contributions to Novvi LLC and to establish how
they will operate Novvi LLC;


 


WHEREAS, in
order to fulfill its initial capital contribution to Novvi LLC under the Amended and Restated Operating Agreement and to enable
Novvi LLC to fulfill its intended purpose to develop, produce, market, and sell Base Oils, Additives, and Lubricants, Amyris and
Novvi LLC executed an IP License Agreement (the “Original License Agreement”) under which Amyris agreed to license
Novvi LLC rights under certain of its intellectual property;


 


WHEREAS, the
Parties amended certain portions of the Original License Agreement on March 21, 2016 through an amendment #1 to the Original License
Agreement;


 


WHEREAS, on
July 19, 2016, due to the addition of American Refining Group, Inc. as a new member of Novvi LLC, Amyris and Cosan US amended and
restated the Amended and Restated Operating Agreement (as such document may be further amended from time-to-time, the “Second
Amended and Restated Operating Agreement”);


 


WHEREAS, in
conjunction with the execution of the Second Amended and Restated Operating Agreement, the Parties desire to further amend and
restate the Original License Agreement through their execution of this License Agreement; and


 


NOW, THEREFORE,
in consideration of the foregoing premises and the mutual covenants contained in this License Agreement, the Parties hereby agree
as follows:


 


ARTICLE 1


 


DEFINITIONS


 


Terms defined in this Article 1 and parenthetically
elsewhere, including the introductory paragraph and the recitals, will have the same meaning throughout this License Agreement
unless otherwise specified.


 


“Additive” means any
material added to a Base Oil to change its properties, characteristics, or performance (e.g., anti-foam, anti-wear, corrosion
inhibitor, detergent, dispersant, pour point depressant, anti-oxidant, viscosity index improver, or friction modifier).




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“Affiliate” means, with
regard to a particular entity (a “First Person”), any person or entity who, directly or indirectly, through
one or more intermediates, Controls the First Person, is Controlled by the First Person, or is under common Control with the First
Person. Notwithstanding the preceding definition, for purposes of this License Agreement, Novvi LLC is not considered an Affiliate
of Amyris or Cosan US (or their respective Affiliates) nor are Amyris and Cosan US (or their respective Affiliates) considered
Affiliates of Novvi LLC.


 


“Alternative Technology”
means a technology (other than a BioFene-related technology) from a renewable source or a molecule (other than a BioFene-derived
molecule) from a renewable source from which Base Oils or Additives, in each case, for the Lubricants Market could reasonably be
expected to be developed or made.


 


“Amyris Base Technology”
means the Patents and Know-How that (i) are Controlled by Amyris as of the Effective Date or become Controlled by Amyris during
the term of Novvi LLC’s licenses under Section 2.1 and (ii) are necessary or reasonably useful for the development, making
(and having made), offering for sale, sale, and importing of Base Oils, Additives, and Lubricants derived from BioFene. For the
avoidance of doubt, the term “Amyris Base Technology” expressly excludes any Amyris BioFene Manufacturing Technology.


 


“Amyris BioFene Manufacturing
Technology” means the Patents and Know-How that (i) are Controlled by Amyris and (ii) are necessary or reasonably useful
for the development, making (and having made), offering for sale, sale, and importing of BioFene itself, including, but not limited
to, the escrowed BioFene Production Strain and any Patents and Know-How related to the genetic engineering of such BioFene Production
Strain, the fermentation methods for making BioFene, the methods of recovery of BioFene from fermentation broth, the processes
of isolating BioFene directly from fermentation broth, and the methods of purifying BioFene. The term “Amyris BioFene Manufacturing
Technology” also includes any and all Joint BioFene Manufacturing Improvements and Novvi LLC BioFene Manufacturing Improvements,
but expressly excludes any Novvi LLC BioFene Transformation Technology


 


“Amyris Breach Invention”
means any and all inventions, discoveries, data, and information, whether or not copyrightable or patentable, conceived, reduced
to practice, made, observed or developed (together with all intellectual property rights related thereto) by or on behalf of Amyris
or its Affiliates or sublicensees, solely or jointly with others, in violation of the license granted to it in Section 2.2.


 


"Amyris Invention" means
any and all inventions, discoveries, data, and information, whether or not copyrightable or patentable, conceived, reduced to practice,
made, observed or developed (together with all intellectual property rights related thereto) by or on behalf of Amyris, solely
or jointly with others. The term “Amyris Invention” includes any improvement by or on behalf of Amyris, solely or jointly
with others, during the term of Amyris’s license under Section 2.2 to Novvi LLC BioFene Transformation Technology, but excludes
Amyris Breach Inventions.


 


“Amyris Pre-Signature Base Technology”
means Amyris Base Technology used by Amyris or an Amyris Affiliate to produce Base Oils or Lubricants offered for sale, sold, or
sampled to Third Parties before the Effective Date.


 


“Applicable Law” means
any law, rule, treaty, or regulation of any governmental authority or any judgment, order, write, decree, permit or license of
any governmental authority of competent jurisdiction, in each case applicable to the Party or activity at issue.



    Page 2 of 37


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“Base Oil” means a fluid
base compound to which other oils, Additives, or components are added to produce a Lubricant.


 


“BioFene” means farnesene
produced through Amyris BioFene Manufacturing Technology.


 


“By-Products” means
those by-products directly resulting from (1) Novvi LLC’s manufacture, under its license in Section 2.1(a)(i), of Base Oils,
Additives, or Lubricants derived from BioFene solely for the Lubricants Market or (2) the manufacture of Base Oils, Additives,
or Lubricants derived from BioFene solely for the Lubricants Market by a permitted sublicensee of Novvi LLC per a sublicense under
Sections 2.1(b) or (c). For clarity, Diesel By-Products are a subset of By-Products.


 


“Copyrights” means all
copyrights, whether in published or unpublished works; databases, data collections and rights therein, mask work rights, software,
web site content; rights to compilations, collective works and derivative works of any of the foregoing and moral rights in any
of the foregoing; registrations and applications for registration for any of the foregoing and any renewals or extensions thereof;
and moral rights and economic rights of others in any of the foregoing.


 


“Control” (including
any variations such as “Controls, “Controlled” or “Controlling”) means:


 


		(i)	in the context of Patents and Know-How, rights under and to such Patents and Know-How held by a
Party, whether by ownership or license, sufficient to grant the applicable license or rights under this License Agreement without
violating the terms of any arrangement with any Third Party; and



 


		(ii)	in the definition of Affiliate, (1) possessing, directly or indirectly, the power to direct the
management or policies, whether through the ownership of voting securities, by contract relating to voting rights or corporate
governance, or otherwise, or (2) ownership, directly or indirectly, of more than fifty percent (50%) of the voting securities or
other ownership interest.



 


“Escrow Agreement” means the
Strain Escrow Agreement, dated July 19, 2016, by and between Amyris, Novvi LLC, and SciSafe Inc., as may be amended from time-to-time.


 


“European Union” means
those countries that were members of the European Union as March 21, 2016, which countries are listed on Exhibit A to this Agreement.”


 


“Exclusivity Exceptions”
means the rights retained by Amyris under Amyris Base Technology for (i) itself and its Affiliates working independently or together,
(ii) Total working independently, and (iii) Total and Amyris (and/or Amyris Affiliates) working together, to develop, make (and
have made), offer for sale, sell, and import Base Oils derived from BioFene for use in the Lubricants Market but only to the extent
such Base Oils are used as a component in such entities’ own Lubricants in such market. For clarity, Total, Amyris and/or
Amyris Affiliates have no retained rights under Amyris Base Technology to develop, make (have made), offer for sale, sell, or import
any Base Oil derived from BioFene for use in the Lubricants Market as a product separate and apart from a finished Lubricant.


 


“Exploit” means to make,
have made, import, use, sell, have sold, distribute, dispose of or offer to dispose of, market, promote or offer for sale including
to research and develop.



    Page 3 of 37


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“Insolvency
Event” means:


 


		(i)	an involuntary petition under any bankruptcy or insolvency law or under the reorganization provisions
of any such law is filed with respect to a Party or a receiver of, or for, the property of a Party is appointed without acquiescence
or consent of such Party, which petition or appointment remains undischarged or unstayed for an aggregate period of ninety (90)
days (whether or not consecutive); or



 


		(ii)	a Party consents to the entry of an order for relief against it in an involuntary case under any
bankruptcy or insolvency law or under the reorganization provisions of any such law; or



 


		(iii)	a voluntary petition under any bankruptcy or insolvency law or under the reorganization provisions
of any such law is filed by a Party, a voluntary assignment of a Party’s property for the benefit of creditors is made, or
a receiver of, or for, the property of a Party is appointed by, or acquiesced or consented to, by such Party.



 


“Joint BioFene Manufacturing Improvements”
means any and all inventions, discoveries, data, and information, whether or not copyrightable or patentable, conceived, reduced
to practice, made, observed or developed (together with all intellectual property rights related thereto) jointly by or on behalf
of Amyris and Novvi LLC (or their respective Affiliates, employees, sublicensees, contractors, or agents) that are based upon,
derived from, incorporating, in connection with or related to Amyris BioFene Manufacturing Technology, including in connection
with the conversion or operation of a sugar/ethanol mill to include the manufacture of BioFene or the operation of such mill or
facility in connection with Novvi LLC’s manufacture of BioFene.


 


“Joint Invention” means
any and all inventions, discoveries, data, and information, whether or not copyrightable or patentable, conceived, reduced to practice,
made, observed or developed (together with all intellectual property rights related thereto) jointly by or on behalf of Amyris
and Novvi LLC (or their respective Affiliates, employees, sublicensees, contractors, or agents) during the term of this License
Agreement, other than Joint BioFene Manufacturing Improvements.


 


“Know-How” means any
non-patented information and tangible materials, including: (i) technical and non-technical data, specifications, formulae, compounds,
formulations, assays, designs, results, information, conclusions, interpretations, inventions, developments, discoveries, ideas,
improvements, and trade secrets, (ii) methods, databases, tests, procedures, processes, and techniques, (iii) escrowed Production
Strains (if applicable), and (iv) other know-how and technology including Copyrights.


 


“Lubricant” means all
substances introduced between two moving surfaces to reduce the friction between them, improving efficiency and reducing wear,
or dissolving or transporting foreign particles, or distributing heat, in each case comprising a formulation of at least one Base
Oil combined or blended with Additives, sold as a finished product for automotive and industrial applications, for use in, by way
of example only: automotive, 2-cycle, marine and other engines, ship lubrication, hydraulic equipment, food processing equipment
and machinery, and wind turbines. However, the term “Lubricants” expressly excludes drilling oils, fluids and muds,
in accordance with the standards set by American Petroleum Institute.


 


“Lubricants Market”
means the worldwide market for automotive, commercial, and industrial Lubricants. For the avoidance of doubt, the following markets,
but not limited to the following markets, are expressly excluded from the term “Lubricants Market”: the markets for
flavors and fragrances, food additives, cosmetics and personal care, drilling oils, fluids and muds, fuels, cleaners, paints, coatings,
ink,



    Page 4 of 37


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consumer-packaged goods, pesticides, and
pharmaceuticals.


 





“Novvi LLC BioFene Transformation
Technology” means the Patents and Know-How in each case that (i) are Controlled by Novvi LLC as of the Effective Date
or become Controlled by Novvi LLC during the term of Amyris’s license under Section 2.2 (in each case other than Patents
and Know-How licensed from Amyris) and (ii) are related to the chemical transformation of BioFene or a BioFene-derivative into
another compound. For clarity, the term “Novvi LLC BioFene Transformation Technology” does not include Novvi LLC Breach
Inventions.


 


"Novvi LLC BioFene
Manufacturing Improvement" means any and all inventions, discoveries, data, and information, whether or not copyrightable
or patentable, conceived, reduced to practice, made, observed or developed (together with all intellectual property rights related
thereto) by or on behalf of Novvi LLC or its Affiliates or sublicensees, solely or jointly with others that are based upon, derived
from, incorporating, in connection with or related to Amyris BioFene Manufacturing Technology.


 


“Novvi LLC Breach
Invention” means any and all inventions, discoveries, data, and information, whether or not copyrightable or patentable,
conceived, reduced to practice, made, observed or developed (together with all intellectual property rights related thereto) by
or on behalf of Novvi LLC or its Affiliates or sublicensees, solely or jointly with others, in violation of the licenses granted
to it in Sections 2.1 or 2.3.


 


"Novvi
LLC Invention" means any and all inventions, discoveries, data, and information, whether or not copyrightable or patentable,
conceived, reduced to practice, made, observed or developed (together with all intellectual property rights related thereto) by
or on behalf of Novvi LLC, solely or jointly with others. The term “Novvi LLC Invention” includes any improvement
by or on behalf of Novvi LLC, solely or jointly with others, during the term of Novvi LLC’s licenses under Section 2.1 to
Amyris Base Technology, but excludes Novvi LLC Breach Inventions and any Novvi LLC BioFene Manufacturing Improvements or Joint
BioFene Manufacturing Improvements.


 


“Patents” means any
patents, patent applications, or certificates of invention, together with all additions, divisions, continuations, continuations-in-part,
provisionals, converted provisionals, substitutions, reissues, re-examinations, revalidations, extensions, registrations, patent
term extensions, supplemental protection certificates, renewals, and the like with respect to any of the foregoing.


 


“Production Strain”
means a recombinant yeast or some other microbial agent that has been genetically engineered to make a desired compound or product
by means of a fermentation process. For clarity, the term Production Strain encompasses populations, subpopulations, and derivatives
of such genetically engineered yeast or other microbial agent.


 


“Third Party” means
any person, corporation, joint venture or other entity, other than Novvi LLC, Amyris, Cosan US, their respective Affiliates, or
their respective permitted successors and assigns.


 


“Total” means Total
Gas & Power USA, SAS, a société par acions simplifiée organized under the laws of the Republic
of France, and its Affiliates.


 






The following terms have the meanings set
forth in the Section set forth opposite such term.


 





	Term	Section
	 	 
	Amended and Restated Operating Agreement
	Recitals
	Amyris	Introductory paragraph



 


 



    Page 5 of 37


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	Amyris Designate	5.9(a)
	Amyris Indemnitees	7.2
	Amyris Third Party Claim	7.2
	Arbitral Tribunal	8.2(c)
	Arbitration Chamber	8.2(b)
	Arbitration Rules	8.2(b)
	Assumption Notice	7.3(b)
	Code	2.6
	Confidential Information	5.10(a)
	Diesel By-Products	4.1
	Disclosing Party	5.10(a)
	Effective Date	Introductory paragraph
	Escrow Agent	2.3(c)
	Escrowed Materials	2.3(c)
	Exercise Notice	3.3(a)
	Indemnification Claim Notice	7.3(a)
	Indemnified Party	7.3(a)
	Indemnifying Party	7.3(a)
	Jet Fuel By-Product	4.2(a)
	License Agreement	Introductory paragraph
	License Conversion Event	2.3(b)
	Losses	7.1
	Novvi LLC	Introductory paragraph
	Novvi LLC Designate	5.9(b)
	Novvi LLC Indemnitees	7.1
	Novvi LLC Third Party Claim	7.1
	Original License Agreement	Recitals
	Parties	Introductory paragraph
	Party	Introductory paragraph
	Receiving Party	5.10(a)
	Representative	5.10(a)
	ROFO	3.1
	ROFO Notice	3.2
	Second Amended and Restated Operating Agreement	Recitals 
	Selected Arbitration	8.2(h)
	SOPs	2.3(c)
	Third Party Claim	7.3(a)




 


ARTICLE 2


 


LICENSE GRANTS


 


2.1Licenses
to Novvi LLC under Amyris Base Technology.


 


(a)Licenses
to Make Base Oils, Additives, and Lubricants from BioFene. Subject to the terms and conditions in this License Agreement, Amyris
hereby grants Novvi LLC:


 


		(i)	an exclusive (except as to the rights retained in the scope of the Exclusivity Exceptions), worldwide,
royalty-free, non-sublicensable (except as set forth in Subsections (b) and (c) below), and non-assignable license under Amyris
Base Technology to Exploit Base Oils, Additives (other than viscosity index improvers), and Lubricants derived from BioFene



 



    Page 6 of 37


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solely for the Lubricants Market
and, as described below in this Section 2.1(a), for such customers outside the Lubricants Market for whom Amyris grants a waiver;
and


 


		(ii)	subject to the limitations in Article 4 restricting the sale of By-Products for use in or
as (i) diesel fuel in the European Union and (ii) jet fuel worldwide, a non-exclusive, worldwide, royalty-free, non-sublicensable,
and non-assignable license under Amyris Base Technology to offer for sale, sell, and import any By-Products



 


		(iii)	a non-exclusive, worldwide, royalty-free, non-sublicensable (except as set forth in Subsections
(b) and (c) below), and non-assignable license under Amyris Base Technology to Exploit Additives that are viscosity index improvers
derived from BioFene solely for the Lubricants Market.



 


Consistent with the scope of
its licenses in (a)(i) and (iii), Novvi LLC and its Affiliates shall not sell any Base Oil, Additive, or Lubricant derived from
BioFene to any Third Party that Novvi LLC or its Affiliates knows has previously resold or used, or intends to resell or use, such
product outside of the Lubricants Market, and Amyris acknowledges that Novvi LLC and its Affiliates will not be responsible for
any resale or use of a Novvi LLC or Novvi LLC Affiliate’s Base Oil, Additive, or Lubricant derived from BioFene outside of
the Lubricants Market by any Third Party whom Novvi LLC or its Affiliates did not know had previously resold or used, or intended
to resell or use, such product outside of the Lubricants Market.


 


If Novvi LLC or its Affiliate
identify an opportunity to sell Base Oil derived from BioFene outside of the Lubricants Market to a potential customer that is
currently using a Base Oil composed of any combinations of Base Oil Groups I-IV as defined by the American Petroleum Institute,
Novvi LLC will provide written notice to Amyris of the opportunity and state the rationale for seeking a waiver to the scope of
the license in Section 2.1(a)(i) regarding such opportunity.  Amyris will promptly consider such waiver request in good faith
and not unreasonably withhold its approval of such request. However, if Amyris has licensed such opportunity to a Third Party or
has an ongoing business relationship with such prospective customer as of the date of such notice, then declining to grant such
waiver will never be considered unreasonable. If Amyris approves a waiver, it must be in writing to be effective, and then the
sale of Base Oil derived from BioFene by Novvi LLC to such potential customer for such approved use, and future sales to such potential
customer for such approved use, will not be a breach of its license hereunder, subject to compliance with the preceding paragraph
regarding knowledge of such customer’s previous or intended use or resale of the products outside such approved use or the
Lubricants Market.


 


(b)Sublicense
Rights to Affiliates. Novvi LLC may sublicense its rights under the licenses granted in Subsections (a)(i) and (iii) to an
Affiliate of Novvi LLC; provided, that,:


 


		(i)	Novvi LLC shall grant such sublicense to an Affiliate only while such entity is and remains an
Affiliate;



 


		(ii)	such sublicense automatically and immediately terminates upon such entity no longer being an Affiliate
of Novvi LLC;



 


		(iii)	each such sublicense to an Affiliate shall be in writing and contain terms that are consistent
in all material respects with this License Agreement including confidentiality terms regarding non-disclosure and non-use of Amyris
Confidential Information and provisions governing intellectual property rights and obligations;



 



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		(iv)	Novvi LLC shall only grant such a sublicense subject to terms that prohibit the Affiliate from
using the sublicensed Amyris Base Technology for any purpose other than to Exploit a Base Oil, Additive, or Lubricant derived from
BioFene solely for the Lubricants Market;



 


		(v)	Novvi LLC shall reasonably monitor such sublicensed Affiliate to ensure it is not violating the
prohibition in clause (iv), its confidentiality obligations, or its intellectual property obligations in a manner consistent with
the procedures Novvi LLC uses to monitor its own licensees and sublicensees to ensure proper use of Novvi LLC’s intellectual
property, but no less than commercially reasonable efforts;



 


		(vi)	Novvi LLC shall retain the right to terminate any such sublicense in the event the applicable sublicensed
Affiliate violates the prohibition in clause (iv), its confidentiality obligations, or its intellectual property obligations; and



 


		(vii)	Novvi LLC shall immediately terminate any such sublicense in the event the applicable sublicensed
Affiliate violates the prohibition in clause (iv), its confidentiality obligations, or its intellectual property obligations and
fails to cure such breach within a reasonable period, which, in no event, shall exceed thirty (30) days after written notice.



 


(c)Limited Sublicense
to Third Party Manufacturing and R&D Subcontractors. Novvi LLC may not sublicense any of its rights under the licenses
granted in Subsections (a)(i) or (iii) to Third Parties, except to a Third Party that is (x) manufacturing for Novvi LLC or an
Affiliate of Novvi LLC, in a subcontractor role, a Base Oil, Additive, and/or Lubricant derived from BioFene for the Lubricants
Market or (y) performing research and development for Novvi LLC or an Affiliate of Novvi LLC, in a subcontractor role, on a Base
Oil, Additive, and/or Lubricant derived from BioFene for the Lubricants Market; provided, that,:


 


		(i)	Novvi LLC shall grant such Third Party manufacturing subcontractor a sublicense only to make, solely
for Novvi LLC or its Affiliates, either a Base Oil, Additive, and/or Lubricant, as the case may be, derived from BioFene solely
for the Lubricants Market; shall grant such Third Party R&D subcontractor a sublicense only to perform research and development,
solely for Novvi LLC or its Affiliates, of Base Oils, Additives, and/or Lubricants, as the case may be, derived from BioFene solely
for the Lubricants Market; and, in each case, shall prohibit such sublicensed Third Party subcontractors from using the sublicensed
Amyris Base Technology for any other purpose;



 


		(ii)	each such sublicense agreement shall be in writing and contain terms that are consistent in all
material respects with this License Agreement including confidentiality terms regarding non-disclosure and non-use of Amyris Confidential
Information and provisions governing intellectual property rights and obligations;



 


		(iii)	Novvi LLC shall reasonably monitor such sublicensed Third Party subcontractors to ensure they are
not violating the prohibitions in clause (i), their confidentiality obligations, or their intellectual property obligations in
a manner consistent with the procedures Novvi LLC uses to monitor its own licensees and sublicensees to ensure proper use of Novvi
LLC’s intellectual property, but no less than commercially reasonable efforts;



 


		(iv)	Novvi LLC shall retain the right to terminate any such sublicense in the event the applicable sublicensed
Third Party subcontractor violates the prohibitions in clause (i),



 



    Page 8 of 37


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its confidentiality
obligations, or its intellectual property obligations; and


 


		(v)	Novvi LLC shall immediately terminate any such sublicense in the event the applicable sublicensed
Third Party subcontractor violates the prohibitions in clause (i), its confidentiality obligations, or its intellectual property
obligations and fails to cure such breach within a reasonable period, which, in no event, shall exceed thirty (30) days after written
notice.



 


(d)No Right
to Manufacture BioFene. For clarity, under the licenses granted in Subsection (a) above, Novvi LLC has no right to make or
have made BioFene under any Amyris intellectual property. The rights of Novvi LLC to make or have made BioFene are set forth in
Section 2.3.


 


2.2License to
Amyris under Novvi LLC BioFene Transformation Technology.


 


(a)License.
Subject to the terms and conditions in this License Agreement, Novvi LLC hereby grants Amyris an exclusive, worldwide, royalty-free,
fully paid-up, sublicensable, and non-assignable license under Novvi LLC BioFene Transformation Technology for any use other than
to Exploit Base Oils, Additives, or Lubricants derived from BioFene for the Lubricants Market.


 


(b)Sublicense
Rights. Amyris may sublicense any of its rights under the license granted in Subsection (a) through multiple tiers of sublicensees;
provided, that,:


 


		(i)	Amyris shall only grant such sublicenses subject to terms that prohibit all such sublicensees,
including direct sublicensees, any sublicensees of such sublicensees, or any other sublicensee pursuant to one of the multiple
tiers of such sublicenses, from using the sublicensed Novvi LLC BioFene Transformation Technology to Exploit any Base Oil, Additive,
or Lubricant derived from BioFene for the Lubricants Market;



 


		(ii)	each such sublicense agreement shall be in writing and contain terms that are consistent in all
material respects with this License Agreement including confidentiality terms regarding non-disclosure and non-use of Novvi LLC’s
Confidential Information and provisions governing intellectual property rights and obligations;



 


		(iii)	Amyris shall reasonably monitor such sublicensees to ensure they are not violating the prohibition
in clause (i), their confidentiality obligations, or their intellectual property obligations in a manner consistent with the procedures
Amyris uses to monitor its own licensees and sub-licensees to ensure proper use of Amyris’s intellectual property, but no
less than commercially reasonable efforts;



 


		(iv)	Amyris shall retain the right to terminate any such sublicense in the event the applicable sublicensee
violates the prohibition in clause (i), its confidentiality obligations, or its intellectual property obligations; and



 


		(v)	Amyris shall immediately terminate any such sublicense in the event the applicable sublicensee
violates the prohibition in clause (i), its confidentiality obligations, or its intellectual property obligations and fails to
cure such breach within a reasonable period, which, in no event, shall exceed thirty (30) days after written notice.



 


2.3License
to Novvi LLC to Manufacture BioFene under Amyris BioFene Manufacturing Technology.



    Page 9 of 37


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(a)Non-Exclusive
License to Manufacture BioFene. Amyris grants, subject to the conditions described below, Novvi LLC a non-exclusive, non-assignable,
royalty-free, and non-sublicensable (except as necessary to exercise its “have made” rights using Third Party subcontractor
manufacturers or Affiliates) license under Amyris BioFene Manufacturing Technology to make and have made BioFene solely to produce
Novvi LLC’s (and, if applicable, Novvi LLC’s Affiliates’) Base Oils, Additives, and Lubricants derived from BioFene
for the Lubricants Market.


 


(b)Conversion
to a Royalty-Bearing License. Should Amyris no longer own any membership units or other equity interest in Novvi LLC (the “License
Conversion Event”), the royalty-free license granted to Novvi LLC under subsection (a) above automatically becomes royalty-bearing,
and within thirty (30) days after the License Conversion Event, the Parties will agree in writing upon a commercially-reasonable
royalty rate and terms for such license. In the event the Parties do not agree within such time period, the Parties will promptly
engage in an accelerated “baseball arbitration” process to determine a commercially-reasonable royalty rate and terms
for the license.


 


(c)Escrowed
Materials. By September 1, 2016, Amyris shall deposit with SciSafe Inc. (the “Escrow Agent”), pursuant to the Escrow
Agreement, (1) the Production Strain presently used by Amyris to commercially produce BioFene and (2) the process, including the
applicable standard operating procedures (“SOPs”), presently used by Amyris to commercially produce BioFene with such
escrowed Production Strain (collectively (1) and (2), as annually updated per the next paragraph, the “Escrowed Materials”).


 


Amyris
shall, on or about every June 30, update the Escrowed Materials by replacing the escrowed Production Strain with the Production
Strain then being used by Amyris to commercially produce BioFene and replacing the escrowed BioFene production process information
with the process, including the applicable SOPs, then used by Amyris to commercially produce BioFene with the newly escrowed Production
Strain. Amyris’s obligations to update the Escrowed Materials shall terminate upon the earlier of (i) the date the Escrowed
Materials are released to Novvi LLC per the procedures in the Escrow Agreement and (ii) thirty (30) days after the date on which
Amyris concludes its BioFene strain development program.


 


(d)Release
of Escrowed Materials to Novvi LLC. Upon release of the Escrowed Materials to Novvi LLC per the procedures in the Escrow Agreement,
Novvi LLC may use the Escrowed Materials only to exercise its license under Subsection (a) above and only at a manufacturing location
(whether such location is owned by Novvi LLC, a Novvi LLC Affiliate, or a Third Party) approved in advance by Amyris in writing,
which approval will not be unreasonably withheld. Immediately upon expiration or earlier termination of its license in Subsection
(a), Novvi LLC will cease its and any Affiliate’s or Third Party’s use of, and will properly destroy, all of the Production
Strain, the other Escrowed Materials, and any other intellectual property of Amyris in Novvi LLC’s, a Novvi LLC’s Affiliate’s
or a Third Party’s possession and certify such destruction in writing to Amyris. 
Novvi LLC may not, and shall not allow any other person or entity to, reverse engineer, engineer, or otherwise genetically modify
the Production Strain or to genetically modify engineer any other strain from the Production Strain and, except as expressly permitted
in this Section 2.3, may not to distribute, disclose or transfer the Production Strain, the other Escrowed Materials, or any other
intellectual property of Amyris to any other person or entity. Despite a release to Novvi LLC, the Escrowed Materials remain the
exclusive property and Confidential Information of Amyris, and such release does not grant any ownership rights or, except as specifically
set forth herein, any other rights of use, express or implied, in the Escrowed Materials to Novvi LLC or any other person or entity.



 


(e)Manufacturing
through an Affiliate or Third Party. To the extent Novvi LLC, in the exercise of its “have made” rights under Subsection
(a), desires to engage an Affiliate or Third Party to



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produce
BioFene for it, such Affiliate or Third Party must execute a binding written contract with Novvi LLC, subject to Amyris’s
prior written approval, containing at least the following provisions before Novvi LLC provides any of the released Escrowed Materials
(including the applicable Production Strain) to such Affiliate or Third Party:


 


		(i)	a covenant by the Affiliate or Third Party to not use the Escrowed Materials except to make BioFene
solely for Novvi LLC per Novvi LLC’s license under Section 2.3(a);



 


		(ii)	a covenant by the Affiliate or Third Party to not reverse engineer the Production Strain, to not
to engineer or genetically modify the Production Strain, and to not distribute, disclose or transfer the Production Strain, the
other Escrowed Materials, or any related intellectual property of Amyris to any other person or entity;



 


		(iii)	a covenant by the Affiliate or Third Party to hold in strict confidence, and to take all reasonable
precautions to protect, the Escrowed Materials (including the Production Strain) and any other Confidential Information of Amyris
that it obtains and to not divulge any of such information or any information derived therefrom to any person, except an employee
who has a need to know for the Affiliate or Third Party to produce BioFene for Novvi LLC;



 


		(iv)	a covenant by the Affiliate or Third Party that its manufacture and supply of BioFene on behalf
of Novvi LLC will, at all times, be conducted in accordance with applicable laws, rules and regulations;



 


		(v)	automatic termination of the Affiliate’s or Third Party’s contract with Novvi LLC and
of its use and possession of the Production Strain, the other Escrowed Materials, or any other intellectual property of Amyris
upon the Affiliate’s or Third Party’s breach of such contract;



 


		(vi)	a covenant by the Affiliate or Third Party that, immediately following termination of the Affiliate’s
or Third Party’s contract with Novvi LLC, it will properly destroy all of the Production Strain, the other Escrowed Materials,
or any other intellectual property of Amyris in the Affiliate’s or Third Party’s possession and certify such destruction
in writing to Amyris;



 


		(vii)	Amyris has the right, at least once per calendar quarter, upon reasonable prior notice and during
normal business hours, to inspect such Affiliate’s or Third Party’s facilities at which BioFene is being manufactured;



 


		(viii)	Amyris has the right, upon reasonable prior notice and during normal business hours, to have a
representative present from time-to-time during the Affiliate’s or Third Party’s manufacture of BioFene;



 


		(ix)	Amyris is expressly named in the contract as a third party beneficiary with the right to enforce
such contract against the Affiliate or Third Party;



 


		(x)	Amyris, as third party beneficiary, is entitled to injunctive or other equitable remedies, in addition
to all other available remedies, against the Affiliate’s or Third Party’s breach or threatened breach of contract with
regard to the Production Strain, the other Escrowed Materials, or any other intellectual property of Amyris without the necessity
of showing irreparable harm, balancing of harms, consideration of the public interest or







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inadequacy of monetary damages
as a remedy and without posting any bond or other security as a condition for obtaining any such relief and the Affiliate or Third
Party irrevocably and unconditionally waives any such requirements;


 


		(xi)	agreement by the Affiliate or Third Party to fully defend, indemnify, and hold harmless Amyris
for the Affiliate’s or Third Party’s actions, inactions or breaches under such contract; and



 


		(xii)	agreement by the Affiliate or Third Party that to obtain and maintain insurance coverage with a
reputable carrier at coverage amounts commercially reasonable for its activities and commitments under such contract.



 


Amyris and Novvi LLC agree that Amyris
has the primary right, but not obligation, to pursue actions against the Affiliate or Third Party to protect the Production Strain,
other Escrowed Materials, and other intellectual property of Amyris.


 


(f)Tech
Transfer. Upon release of the Escrowed Materials to Novvi LLC per the procedures in the Escrow Agreement, Amyris agrees to
provide a one-time, site-specific, and reasonable amount (but no more than one hundred (100) hours) of technical assistance to
Novvi LLC to enable Novvi LLC to implement the Escrowed Materials consistent with the license in subsection (a). However, due to
the potential variances in manufacturing facilities, equipment, capabilities, personnel, experience, locations, infrastructure,
and/or operations, there is no guarantee of successful implementation or performance of the Escrowed Materials at any facility,
even after the one-time technical assistance.


 


(g)Disputes.
Any dispute between the Parties regarding the deposit or release of the Escrowed Materials shall be resolved as provided in Section 8.2.


 



2.4No Implied
or Additional Rights or Licenses. Except as specified in this License Agreement, Amyris grants no rights to Novvi LLC to use
any of Amyris’s Confidential Information or intellectual property. Except as specified in this License Agreement, Novvi LLC
grants no rights or licenses to Amyris to use any of Novvi LLC’s Confidential Information or intellectual property.


 


2.5Novvi LLC
Efforts in Brazil. Novvi LLC agrees it will exert commercially reasonable efforts to
use the licensed technology in order to try to maintain the validity of the Patents in the Amyris Base Technology and, if licensed
to Novvi LLC, in the Amyris BioFene Manufacturing Technology and any Alternative Technology, in each case in the territory of Brazil.


 


2.6Effect of
Bankruptcy on the Licenses. All rights and licenses granted under this Article 2 by Amyris or Novvi LLC are, and shall otherwise
be deemed to be, for purposes of Section 365(n) of the U.S. Bankruptcy Code (the “Code”), licenses of rights
to “intellectual property” as defined under Section 101 of the Code. The Parties agree that, in the event of a Party’s
Insolvency Event, the other Party in its capacity as a licensee under this Article 2 will, to the extent that its license is still
in effect at the time of such Insolvency Event, retain and may fully exercise all of its rights and elections under the Code (or
any same or similar provision in any jurisdiction other than the United States) with regard to such license and rights, subject
to payments due the licensor Party (if any) as a result of the exercise of such rights and subject to the terms and conditions
of such license and rights set forth in this License Agreement.


 


The Parties further agree
that, in any Insolvency Event involving a Party, that the other Party will be entitled to a complete duplicate of (or complete
access to, as appropriate) any such intellectual property



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licensed to such licensee
Party under its continuing license and all tangible embodiments of such intellectual property, and same, if not already in its
possession, will be promptly delivered to the licensee Party (i) upon any such commencement of a bankruptcy proceeding upon such
licensee Party’s written request or (ii) if not promptly delivered under (i) above, following any rejection of this License
Agreement by or on behalf of such Party (e.g. by a bankruptcy trustee), upon written request for such transfer by the licensee
Party. For the avoidance of doubt, nothing in this clause may be construed as forcing a Party to act in breach of any mandatory
bankruptcy laws and regulations applicable in its jurisdiction.


 


 


ARTICLE 3


 


RIGHT OF FIRST OFFER REGARDING ALTERNATIVE
TECHNOLOGY


 


3.1Right of
First Offer to Amyris’s Alternative Technology. Notwithstanding the exclusivity provisions in Section 13.01 of the Second
Amended and Restated Operating Agreement, if while Novvi LLC’s licenses under Section 2.1 are in effect, Amyris (i)
develops, acquires, or in-licenses an Alternative Technology and (ii) wishes to exclusively license or sell to a Third Party the
use or ownership of such Alternative Technology for purposes of developing, making (having made), offering for sale, selling, or
importing Base Oils, Additives, or Lubricants for the Lubricants Market, then, prior to engaging in a discussion with any Third
Party or soliciting an offer from any Third Party in this respect, Amyris shall first offer Novvi LLC the right to exclusively
license or acquire (subject to the Exclusivity Exceptions) use or ownership of such Alternative Technology for the development,
making (having made), offering for sale, sale, and importation of Base Oils, Additives, and Lubricants solely in the Lubricants
Market (“ROFO”); provided such ROFO does not violate the terms of any arrangement with any Third Party from
whom Amyris acquired or licensed such Alternative Technology, if applicable.


 


For the avoidance of doubt, the foregoing
ROFO obligation shall not apply to an Alternative Technology developed by Amyris in connection with activities that fall within
an Exclusivity Exception.


 


3.2ROFO Notice.
Amyris shall promptly notify Novvi LLC in writing when it has an Alternative Technology that is subject to the ROFO (a “ROFO
Notice”). The ROFO Notice shall include a reasonable description of the applicable Alternative Technology and the fundamental
license and/or sale terms and conditions proposed by Amyris.


 


 3.3 Exercise of the ROFO.




 


(a)Due Diligence
Period. Novvi LLC shall have sixty (60) days from receipt of a ROFO Notice to (i) conduct an assessment of the applicable Alternative
Technology (and, for such purpose, Amyris hereby undertakes to provide to Novvi LLC all information it believes in good faith is
necessary for Novvi LLC’s full and complete assessment) and (ii) deliver to Amyris a written notice expressing its intention
to exercise its ROFO (an “Exercise Notice”).


 


(b)Negotiation
Period. In the event it delivers an Exercise Notice per Subsection (a) above, Novvi LLC shall be obligated, within sixty (60)
days from Amyris’s receipt of the Exercise Notice, to enter into a definitive agreement with Amyris (separate from this License
Agreement) regarding either an exclusive license to, or acquisition of, (subject to the Exclusivity Exceptions) the use or ownership
of such Alternative Technology for the development, making (having made), offering for sale, sale, and importation of Base Oils,
Additives, and Lubricants solely in the Lubricants Market and on terms and conditions consistent with those referred to in the
ROFO Notice. In addition, any license granted by



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Amyris to Novvi LLC with regard to Alternative
Technology shall be terminable upon the expiration or earlier termination of Novvi LLC’s licenses under Section 2.1.


 


(c)Negotiate
with Third Parties. If Novvi LLC does not deliver an Exercise Notice in compliance with Subsection (a) above or is not successful
in executing a definitive agreement with Amyris within the sixty (60) days in Subsection (b) above, then Amyris shall be free to
solicit and negotiate with any Third Party the exclusive license or sale of such Alternative Technology, provided that (i)
the economic terms offered by such Third Party shall be no less favorable to Amyris than those offered by Novvi LLC under the ROFO
Notice; (ii) the fundamental business terms, including the structure of the relevant transaction (e.g., sale, license, formation
of a joint venture and contribution of the Alternative Technology), are substantially the same as those offered to Novvi LLC under
the ROFO Notice; and (iii) Amyris and the Third Party have entered into a definitive agreement within one hundred and twenty (120)
days after the end of the sixty (60) day period in Subsections (a) or (b) above, whichever is applicable.


 


3.4Repetition
of ROFO. If Amyris and the Third Party have not entered into a definitive agreement in compliance with Section 3.3(c) above,
then Amyris must again comply with the provisions of the ROFO before exclusively licensing or selling to a Third Party the use
or ownership of such Alternative Technology for purposes of Base Oils, Additives, or Lubricants in the Lubricants Market.


 


3.5Alternative
Technology Production Strain Restrictions. If an Alternative Technology to be exclusively licensed to Novvi LLC by Amyris under
this Article 3 includes rights for Novvi LLC to manufacture or have manufactured such Alternative Technology with a Production
Strain, the Parties hereby agree that such manufacturing license granted to Novvi LLC shall be conditioned on, among other things,
compliance with provisions equivalent to those for BioFene in Section 2.3 above.


 


3.6Termination
of Article 3. Upon the expiration or earlier termination of Novvi LLC’s licenses under Section 2.1, all rights and obligations
of the Parties under this Article 3 automatically terminate, and this Article 3 will be of no further effect.


 


 


ARTICLE 4


 


SALE OF BY-PRODUCTS 


 


4.1No Sale of
By-Products as Diesel Fuel in the European Union. Novvi LLC agrees that it shall not, at any time, offer for sale or sell any
By-Products, including, but not limited to, any farnesane or diesel-related By-Products (“Diesel By-Products”),
for use in or as diesel fuel in any of the European Union.


 


4.2No Sale of
Jet Fuel By-Products except to Amyris; Amyris’s Obligation to Purchase.


 





(a)               
Novvi LLC agrees that it will not offer for sale or sell any Jet Fuel By-Products to any person or entity except to Amyris
as set forth in this Section 4.2, and Amyris agrees that it will purchase all such Jet Fuel By-Products. As used in this Section,
“Jet Fuel By-Product” means a By-Product (i) whose concentration of farnesane, partially hydrogenated farnesene
or farnesene, by volume, is at least [*] or greater; and (ii) that when blended with petroleum-derived jet fuel, meets the ASTM
D1655 and D7566 specifications (or successors thereto) for use as a jet fuel.



 


(b)              
The purchase price payable by Amyris to Novvi LLC for each liter of any Jet Fuel By-Product will be equal to the price per
liter that Amyris sells farnesene to Novvi LLC, in case such


 





[*] Certain portions denoted with an asterisk have been omitted
and filed separately with the Securities and Exchange Commission. Confidential treatment has been requested with respect to the
omitted portions.











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price is higher than US$ [*] per liter. If the per liter of
farnesene price Amyris charges to Novvi LLC is below US$ [*] per liter, Amyris will purchase such Jet Fuel By-Product at the NYMEX
ULSD diesel one-month forward price.



 


(c)               
In connection with the sale of any By-Products by Novvi LLC to a third party, Novvi LLC shall require any such purchaser
to agree in writing that (i) such By-Products may not be used in or as diesel fuel in the European Union or in or as jet fuels
anywhere, and (ii) if any such By-Products are incorporated into any diesel fuel outside the European Union, that such diesel fuels
may not be imported into any of the European Union.


 


(d)              
Other than as set forth in this Section, Amyris has no obligation or rights to purchase any By-Products from Novvi LLC.


 


4.3No Other Limits on Novvi LLC.
Other than as set forth in this Article 4, Novvi LLC may, pursuant to its license in Section 2.1(a)(ii), freely offer for
sale, sell, and import its By-Products.


 


ARTICLE 5


 


INTELLECTUAL PROPERTY


 


5.1Inventorship.
Inventorship of all inventions and discoveries conceived, reduced to practice, discovered or made pursuant to this License
Agreement, whether or not patentable, shall be determined in accordance with U.S. patent laws. Other than as set forth below, as
among the Parties, ownership of all inventions and discoveries conceived, reduced to practice, discovered or made or created during
the Term of this License Agreement shall be determined consistent with inventorship.


 


5.2Amyris’s
Ownership. Amyris’s intellectual property ownership rights are as follows:


 


(a)               
Amyris Base Technology, Amyris BioFene Manufacturing Technology, Amyris Inventions, and Amyris Alternative Technology.
As between the Parties, all rights, title, and interest in and to Amyris Base Technology, Amyris BioFene
Manufacturing Technology, Amyris Inventions, and Amyris’s Alternative Technology are exclusively owned solely by Amyris.
Novvi LLC and its Affiliates, sublicensees, contractors, agents, and employees shall
have no right, license or permission to practice Amyris Base Technology, Amyris BioFene Manufacturing Technology, or Amyris Inventions,
or Amyris’s Alternative Technology except to the extent the licenses described in Sections 2.1 and 2.3 or Article 3 are in
place between the Parties.


 


(b)              
Joint BioFene Manufacturing Improvements and Novvi LLC BioFene Manufacturing Improvements. All rights, title, and
interest in and to Joint BioFene Manufacturing Improvements and Novvi LLC BioFene Manufacturing Improvements are exclusively owned
solely by Amyris. Novvi LLC will promptly disclose Joint BioFene Manufacturing Improvements and Novvi LLC BioFene Manufacturing
Improvements, if any, in writing to Amyris and, without further consideration, hereby assigns to Amyris any and all rights, title
and interests of Novvi LLC (and, as applicable, its Affiliates, sublicensees, contractors, agents, and employees) in and to all
Joint BioFene Manufacturing Improvements and Novvi LLC BioFene Manufacturing Improvements.


 


Upon Amyris’s reasonable request
and at Amyris’s expense, Novvi LLC will promptly perform (or cause, as applicable, its Affiliates, sublicensees, contractors,
agents, and employees to promptly perform) any and all acts necessary, including the execution and delivery of any and all affidavits,
declarations, oaths, exhibits, assignments, powers of attorney, or other documentation as may be reasonably required, to perfect
the delivery, assignment, and conveyance to Amyris, its successors, assigns, and nominees, of


 





[*] Certain portions denoted with an asterisk
have been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been requested with
respect to the omitted portions.














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the entire right, title, and interest in
and to all Joint BioFene Manufacturing Improvements and Novvi LLC BioFene Manufacturing Improvements.


 


For purposes of this License Agreement,
Joint BioFene Manufacturing Improvements and Novvi LLC BioFene Manufacturing Improvements will be considered Amyris BioFene Manufacturing
Technology, and Novvi LLC and its Affiliates, sublicensees, contractors, agents, and employees shall have no right, license or
permission to practice Joint BioFene Manufacturing Improvements or Novvi LLC BioFene Manufacturing Improvements except to the extent
the license described in Section 2.3 is in place between the Parties.


 


(c)               
Novvi LLC Breach Inventions. All rights, title, and interest in and to Novvi LLC Breach Inventions are also exclusively
owned solely by Amyris. Novvi LLC will promptly disclose Novvi LLC Breach Inventions, if any, in writing to Amyris and, without
further consideration, hereby assigns to Amyris any and all rights, title and interests of Novvi LLC (and,
as applicable, its Affiliates, sublicensees, contractors, agents, and employees) in and to Novvi LLC Breach Inventions.


 


Upon Amyris’s reasonable request
and at Amyris’s expense, Novvi LLC will promptly perform (or cause, as applicable, its Affiliates, sublicensees, contractors,
agents, and employees to promptly perform) any and all acts necessary, including the execution and delivery of any and all affidavits,
declarations, oaths, exhibits, assignments, powers of attorney, or other documentation as may be reasonably required, to perfect
the delivery, assignment, and conveyance to Amyris, its successors, assigns, and nominees, of the entire right, title, and interest
in and to all Novvi LLC Breach Inventions.


 


For purposes of this License Agreement,
Novvi LLC Breach Inventions will be considered Amyris Inventions, and Novvi LLC and its Affiliates, sublicensees, contractors,
agents, and employees shall have no right, license or permission to practice Novvi LLC Breach Inventions.


 


5.3Novvi LLC’s
Ownership. Novvi LLC’s intellectual property ownership rights are as follows:


 


(a)Novvi LLC
BioFene Transformation Technology and Novvi LLC Inventions. As between the Parties, all rights, title, and interest in and
to Novvi LLC BioFene Transformation Technology and Novvi LLC Inventions are exclusively owned solely by Novvi LLC. Amyris and its
Affiliates, sublicensees, contractors, agents, and employees shall have no right, license or permission to practice Novvi LLC BioFene
Transformation Technology or Novvi LLC Inventions except to the extent the license described in Section 2.2 is in place between
the Parties.


 


(b)Amyris Breach
Inventions. All rights, title, and interest in and to Amyris Breach Inventions are also exclusively owned solely by Novvi LLC.
Amyris will promptly disclose Amyris Breach Inventions, if any, in writing to Novvi LLC and, without further consideration, hereby
assigns to Novvi LLC any and all rights, title and interests of Amyris (and, as applicable, its Affiliates,
sublicensees, contractors, agents, and employees) in and to Amyris Breach Inventions.


 


Upon Novvi LLC’s reasonable request
and at Novvi LLC’s expense, Amyris will promptly perform (or cause, as applicable, its Affiliates, sublicensees, contractors,
agents, and employees to promptly perform) any and all acts necessary, including the execution and delivery of any and all affidavits,
declarations, oaths, exhibits, assignments, powers of attorney, or other documentation as may be reasonably required, to perfect
the delivery, assignment, and conveyance to Amyris, its successors, assigns, and nominees, of the entire right, title, and interest
in and to all Amyris Breach Inventions.


 


For purposes of this License Agreement,
Amyris Breach Inventions will be considered Novvi Inventions,



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and Amyris
and its Affiliates, sublicensees, contractors, agents, and employees shall have no right, license or permission to practice
Amyris Breach Inventions.


 


5.4Joint Inventions.
Joint Inventions will be jointly owned by Amyris and Novvi LLC, and the Parties will have co-exclusive rights to use and practice
Joint Inventions (i.e., neither Party can individually grant another person or entity any exclusive rights) and without
accounting.


 


5.5Semi-Annual
Updates to Amyris regarding Novvi LLC BioFene Transformation Technology. Every January 15 and July 15 while Amyris’s
license under Section 2.2 is in effect, Novvi LLC will provide Amyris with a written update on Novvi LLC BioFene Transformation
Technology. Such semi-annual updates will include a list of any Patents in the Novvi LLC BioFene Transformation Technology identified
by their respective title, inventors, serial numbers, filing date, and status. Novvi LLC also agrees to copy Amyris on any official
correspondence between Novvi LLC (or Novvi LLC’s counsel) and any patent office regarding Patents in Novvi LLC BioFene Transformation
Technology.


 


5.6Semi-Annual
Updates to Novvi LLC regarding Amyris Base Technology. Every January 15 and July 15 while Novvi LLC’s license under Section
2.1 is in effect, Amyris will provide Novvi LLC with a written update on Amyris Base Technology. Such semi-annual updates will
include a list of any Patents in the Amyris Base Technology identified by their respective title, inventors, serial numbers, filing
date, and status. Amyris also agrees to copy Novvi LLC on any official correspondence between Amyris (or Amyris’ counsel)
and any patent office regarding Patents in Amyris Base Technology.


 


5.7Semi-Annual
Updates to Novvi LLC regarding Amyris BioFene Manufacturing Technology. Following the technical transfer from Amyris to Novvi
LLC described in Section 2.3, every January 15 and July 15 while Novvi LLC’s license under Section 2.3 remains in effect,
Amyris will provide Novvi LLC with a written update on Amyris BioFene Manufacturing Technology. Such semi-annual updates will include
a list of any Patents in the Amyris BioFene Manufacturing Technology identified by their respective title, inventors, serial numbers,
filing date, and status. Amyris also agrees to copy Novvi LLC on any official correspondence between Amyris (or Amyris’ counsel)
and any patent office regarding Patents in Amyris BioFene Manufacturing Technology.


 


5.8Patent Strategy
and Prosecution.


 


(a)Amyris’s
Rights. As between the Parties, Amyris shall have the sole right and discretion to: (i) determine the process for protecting
any Amyris Inventions (as well as any Amyris Base Technology and any Amyris BioFene Manufacturing Technology) worldwide, including
whether or not to obtain Patent protection and in what countries and (ii) at its own expense, but without obligation, prepare,
file, prosecute, maintain, and defend throughout the world any and all Patents claiming or relating to the Amyris Inventions, Amyris
Base Technology and Amyris BioFene Manufacturing Technology or, at any time, abandon or discontinue such activities.


 


Upon Amyris’s reasonable request
and at Amyris’s expense, Novvi LLC will promptly perform (or cause, as applicable, its Affiliates, sublicensees, contractors,
agents, and employees to promptly perform) any and all acts necessary, including the execution and delivery of any and all affidavits,
declarations, oaths, exhibits, assignments, powers of attorney, or other documentation as may be reasonably required, to allow
Amyris to apply for, register, obtain, maintain, defend, and enforce any Patent claiming or relating to any Joint BioFene Manufacturing
Improvements, Novvi LLC BioFene Manufacturing Improvements, or Novvi LLC Breach Inventions and/or its rights therein.


 


(b)Novvi LLC’s
Rights. As between the Parties, Novvi LLC shall have the sole right and


 



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discretion to (i) determine the process
for protecting any Novvi LLC Inventions (as well as any Novvi LLC BioFene Transformation Technology) worldwide, including whether
or not to obtain Patent protection and in what countries and (ii) at its own expense, but without obligation, prepare, file, prosecute,
maintain, and defend throughout the world any and all Patents claiming or relating to the Novvi LLC Inventions and Novvi LLC BioFene
Transformation Technology or, at any time, abandon or discontinue such activities.


 


Upon Novvi LLC’s reasonable request
and at Novvi LLC’s expense, Amyris will promptly perform (or cause, as applicable, its Affiliates,
sublicensees, contractors, agents, and employees to promptly perform) any and all acts necessary, including the execution
and delivery of any and all affidavits, declarations, oaths, exhibits, assignments, powers of attorney, or other documentation
as may be reasonably required, to allow Novvi LLC to apply for, register, obtain, maintain, defend, and enforce any Patent claiming
or relating to any Amyris Breach Invention and/or its rights therein.


 


(c)Joint
Inventions Rights. For each Joint Invention, the Parties will mutually select which Party
shall have the sole right and discretion to (i) determine the process for protecting such Joint Invention worldwide, including
whether or not to obtain Patent protection and in what countries and (ii) at its own expense, but without obligation, prepare,
file, prosecute, maintain, and defend throughout the world any and all Patents claiming or relating to such Joint Invention or,
at any time, abandon or discontinue such activities.


 


5.9Infringement
by Third Parties.


 


(a)Amyris Base
Technology and Amyris BioFene Manufacturing Technology. In the event either Party becomes aware of any Third Party activity
that infringes or misappropriates (or is likely to infringe or misappropriate) Amyris Base Technology or Amyris BioFene Manufacturing
Technology, that Party will notify the other Party promptly in writing of the actual or threatened infringement or misappropriation.
Whether or not to take action against such infringement or misappropriation will be the sole right, and at the sole discretion,
of Amyris or its designated representative (“Amyris Designate”). However, at Amyris’s expense, Novvi LLC
will cooperate to the extent reasonably required by Amyris or the Amyris Designate to stop such infringement or misappropriation,
and, if so requested by Amyris, will join with Amyris or the Amyris Designate as a party to any action brought by Amyris or the
Amyris Designate for such purpose. Amyris or the Amyris Designate will have full control over any action taken, including, without
limitation, the right to select counsel, to settle on any terms it deems advisable in its discretion, to appeal any adverse decision
rendered in any court, to discontinue any action taken by it, and otherwise to make any decision in respect thereto as it in its
discretion deems advisable.


 


(b)Novvi LLC
BioFene Transformation Technology. In the event either Party becomes aware of any Third Party activity that infringes or misappropriates
(or is likely to infringe or misappropriate) Novvi LLC BioFene Transformation Technology, that Party will notify the other Party
promptly in writing of the actual or threatened infringement or misappropriation. Whether or not to take action against such infringement
or misappropriation will be the sole right, and at the sole discretion, of Novvi LLC or its designated representative (“Novvi
LLC Designate”). However, Amyris will cooperate to the extent reasonably required by Novvi LLC or the Novvi LLC Designate
to stop such infringement or misappropriation, and, if so requested by Novvi LLC, will join with Novvi LLC or the Novvi LLC Designate
as a party to any action brought by Novvi LLC or the Novvi LLC Designate for such purpose. Novvi LLC or the Novvi LLC Designate
will have full control over any action taken, including, without limitation, the right to select counsel, to settle on any terms
it deems advisable in its discretion, to appeal any adverse decision rendered in any court, to discontinue any action taken by
it, and otherwise to make any decision in respect thereto as it in its discretion deems advisable.



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5.10Confidentiality
Obligations.


 


(a)Confidential
Information. As used herein, “Confidential Information” means any and all
information provided by or on behalf of a Party (“Disclosing Party”) to the other Party (“Receiving
Party”) or to its Representatives between the Effective Date and the termination of this License Agreement, regardless
of the form or medium of communication, that relates to the Disclosing Party’s intellectual property licensed or created
under this License Agreement or its activities under this License Agreement, in each case which information is either proprietary
to the Disclosing Party or is otherwise not available to the general public. The Parties agree to treat this License Agreement
as the Confidential Information of the other Party. As used herein, “Representative” means the officers, directors,
members, shareholders, employees, attorneys, accountants, advisors, consultants, auditors, agents, contractors, and sublicensees
of the applicable Party and of its Affiliates. 


 


(b)Obligations.
Except with the prior written consent of the Disclosing Party or as specifically authorized in this License Agreement, each Receiving
Party shall, and shall cause its Representatives (to the extent such persons receive any Confidential Information) to,:


 


		(i)	maintain in confidence any and all Confidential Information;



 


		(ii)	take reasonable precautions to protect Confidential Information;



 


		(iii)	not disclose Confidential Information to any person or entity;
and 



 


		(iv)	not make any use of such Confidential Information except for
the purposes specifically authorized herein. 



 


(c)Permitted
Disclosures. A Receiving Party may disclose Confidential Information, without the Disclosing Party’s written consent,
to those of its Representatives who (i) need to know such Confidential Information for the purpose of assisting such Receiving
Party fulfill its obligations or exercise its rights under this License Agreement and (ii) are bound by written obligations of
confidentiality and non-use substantially similar to those herein.  A Receiving Party or its Affiliates may also disclose
the terms of this License Agreement to actual or prospective investors, underwriters, or acquirers who need to know such Confidential
Information to evaluate the Receiving Party’s (or its Affiliates’) business and who are bound by written obligations
of confidentiality and non-use substantially similar to those herein.


 


(d)Legally
Required Disclosures. In addition, a Receiving Party may disclose Confidential Information (including the terms of this License
Agreement), without the Disclosing Party’s written consent, to the extent such disclosure is required, on advice of counsel,
by Applicable Law (including pursuant to any listing agreement with, or the rules or regulations of, any national securities exchange
on which any securities of such Receiving Party or any Affiliate thereof are listed or traded); provided, that the Receiving
Party making such disclosure, or whose Affiliates are making such disclosure, shall notify the other Party as promptly as practicable
(and if possible and legally allowed, prior to making such disclosure) and shall minimize such disclosure as much as possible and
reasonably seek confidential treatment of such Confidential Information to the extent available. 


 


(e)Exceptions
to Confidential Information. The provisions of Subsection (b) above shall not apply to, and Confidential Information shall
not include, any information of a Disclosing Party that:


 


		(i)	is or has become generally available to the
public other than as a result of a disclosure by a Receiving Party or any of its Representatives in breach of this Section 5.10;



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		(ii)	has been independently developed by a Receiving
Party (or any Affiliate thereof) without violating any of the provisions of this License Agreement or any other similar contract
to which such Receiving Party or any of its Representatives, is or are bound; or



 


		(iii)	was made available to a Receiving Party (or
any Affiliate thereof), on a non-confidential basis by a Third Party who is not prohibited from disclosing such information to
such person or entity by a legal, contractual or fiduciary obligation to the Disclosing Party or any of its Representatives.



 


(f)Public
Announcements. Except as required by Applicable Law or by the requirements of any national
securities exchange on which the securities of a Party (or its Affiliates) are listed or traded, no Party shall make, or
cause to be made, any press release or public announcement in respect of this License Agreement or otherwise communicate with
any news media without the prior written consent of the other Party, and the Parties shall cooperate as to the timing and
contents of any such press release or public announcement. 


 


(g)Duration
of Obligations. Except as otherwise provided for in this Section 5.10, Confidential Information received hereunder shall be
used by each Receiving Party and its Representatives solely in connection with such Receiving Party fulfilling its obligations
or exercising its rights under this License Agreement. Nothing in this License Agreement shall be interpreted as vesting, in favor
of any Receiving Party or any other person or entity, any right of ownership or other right in the Confidential Information of
a Disclosing Party. The obligations under this Section 5.10 shall survive for two (2) years after the termination of this
License Agreement.


 


 


ARTICLE 6


 


REPRESENTATIONS, WARRANTIES, AND DISCLAIMERS


 


6.1Representations
and Warranties by Amyris. Amyris hereby represents and warrants to Novvi LLC that, as of the Effective Date,:


 


(a)Organization;
Good Standing. Amyris is a corporation duly organized and in good standing under the laws of Delaware and has full power and
authority and the legal right to own and operate its property and assets and to carry on its business as it is now being conducted
and as is contemplated to be conducted by this License Agreement.


 


(b)Corporate
Authority. Amyris has the power and authority and the legal right to enter into this License Agreement and perform its obligations
hereunder and has taken all necessary action on its part required to authorize the execution and delivery of this License Agreement
and the performance of its obligations hereunder. 


 


(c)Binding
Obligation. This License Agreement has been duly executed and delivered by Amyris and constitutes a legal, valid, and binding
obligation of Amyris and is enforceable against it in accordance with its terms subject to the effects of bankruptcy, insolvency
or other laws of general application affecting the enforcement of creditor rights and judicial principles affecting the availability
of specific performance and general principles of equity, whether enforceability is considered in a proceeding at law or equity.


 



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(d)Consents
and Approvals. All necessary consents, approvals and authorizations of all regulatory and governmental authorities and other
persons or entities required to be obtained by Amyris in connection with the execution and delivery of this License Agreement and
the performance of its obligations hereunder have been obtained or will be obtained prior to such performance. 


 


(e)No
Conflicts. The execution and delivery of this License Agreement and the performance of Amyris’s obligations hereunder
(i) do not conflict with or violate any provision of Amyris’s articles of incorporation or bylaws, (ii) do not conflict with,
violate, or constitute a default of any contractual obligation of Amyris, or (iii), to its knowledge, do not conflict with or violate
any requirement of Applicable Law.


 


(f)Amyris Base Technology.
Amyris owns or otherwise has all necessary rights in and to the Amyris Base Technology to grant Novvi LLC the licenses described
in Sections 2.1 and 2.3.


 


6.2Representations
and Warranties by Novvi LLC. Novvi LLC hereby represents and warrants to Amyris that, as of the Effective Date,:


 


(a)Organization;
Good Standing. Novvi LLC is a limited liability company duly organized and in good standing under
the laws of Delaware and has full power and authority and the legal right to own and operate its property and assets and to carry
on its business as it is now being conducted and as it is contemplated to be conducted by this License Agreement.


 


(b)Corporate
Authority. Novvi LLC has the power and authority and the legal right to enter into this License Agreement and perform its obligations
hereunder and has taken all necessary action on its part required to authorize the execution and delivery of this License Agreement
and the performance of its obligations hereunder. 


 


(c)Binding
Obligation. This License Agreement has been duly executed and delivered by Novvi LLC and constitutes a legal, valid, and binding
obligation of Novvi LLC and is enforceable against it in accordance with its terms subject to the effects of bankruptcy, insolvency
or other laws of general application affecting the enforcement of creditor rights and judicial principles affecting the availability
of specific performance and general principles of equity, whether enforceability is considered in a proceeding at law or equity.


 


(d)Consents
and Approvals. All necessary consents, approvals and authorizations of all regulatory and governmental authorities and other
persons or entities required to be obtained by Novvi LLC in connection with the execution and delivery of this License Agreement
and the performance of its obligations hereunder have been obtained or will be obtained prior to such performance. 


 


(e)No
Conflicts. The execution and delivery of this License Agreement and the performance of Novvi LLC’s obligations hereunder
(i) do not conflict with or violate any provision of Novvi LLC’s certificate of incorporation or Second Amended and Restated
Operating Agreement, (ii) do not conflict with, violate, or constitute a default of any contractual obligation of Novvi LLC, or
(iii), to its knowledge, do not conflict with or violate any requirement of Applicable Law.


 


6.3DISCLAIMER OF WARRANTIES.
EXCEPT AS EXPRESSLY SET FORTH IN THIS ARTICLE 6, NEITHER PARTY MAKES ANY REPRESENTATIONS OR GRANTS ANY WARRANTY, EXPRESS OR IMPLIED,
EITHER IN FACT OR BY OPERATION OF LAW, BY STATUTE OR OTHERWISE, AND EACH PARTY SPECIFICALLY DISCLAIMS ANY OTHER WARRANTIES, WHETHER
WRITTEN OR ORAL, OR EXPRESS OR IMPLIED, INCLUDING ANY WARRANTY OF QUALITY, MERCHANTABILITY, FITNESS FOR A PARTICULAR USE



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OR PURPOSE, OR SAFETY, ANY WARRANTY AS
TO THE ACCURACY, VALIDITY OR SCOPE OF ANY PATENTS OR KNOW-HOW LICENSED HEREUNDER, AND ANY WARRANTY AS TO THE NON-INFRINGEMENT OF
ANY THIRD PARTY’S INTELLECTUAL PROPERTY RIGHTS THROUGH THE PRACTICE OF ANY PATENTS OR KNOW-HOW LICENSED HEREUNDER.


 


 


ARTICLE 7


 


INDEMNIFICATION


 


7.1Amyris’s
Indemnification Obligations. Amyris will defend, indemnify, and hold harmless Novvi LLC, its Affiliates and its and their respective
members, directors, officers, employees, and agents and their respective successors, heirs, and permitted assigns (collectively,
“Novvi LLC Indemnitees”) from and against any and all losses, damages, liabilities, fines, costs, interest and
expenses (including reasonable attorneys’ fees and expenses) (collectively, “Losses”) arising from a Third
Party’s claim, action, suit, or demand (or judgments or settlements arising therefrom) against a Novvi LLC Indemnity, in
each case to the extent resulting from: 


 


		(i)	any breach by Amyris of this License Agreement;




 


		(ii)	the negligent, reckless, or intentionally
wrongful acts or omissions on the part of any Amyris Indemnitee in performing any activity related to this License Agreement;



 


		(iii)	Amyris’s development, making, having
made, offer for sale, sale, or import of any product for which it used Novvi LLC BioFene Transformation Technology licensed to
it under Section 2.2, including any claims of product liability or claims of infringement or misappropriation of a Third Party’s
intellectual property; 



 


		(iv)	Novvi LLC’s making (have made), offer
for sale, sale, or importing, in each case between the Effective Date and June 1, 2013, of any Base Oil or Lubricant for the Lubricants
Market derived from BioFene using Amyris Pre-Signature Base Technology allegedly infringing or misappropriating a Third Party’s
intellectual property but only to the extent such alleged infringement or misappropriation is directly attributable to Novvi LLC’s
adherence to the Amyris Pre-Signature Base Technology and not to any deviation or modification from such process made by or on
behalf Novvi LLC or a permitted sublicensee of Novvi LLC, other than a deviation or modification made by Novvi LLC at the written
direction of Amyris; 



 


		(v)	if Novvi LLC is licensed under Section 2.3
to make BioFene, Novvi LLC’s manufacture of BioFene in either the United States of America or Brazil allegedly infringing
or misappropriating a Third Party’s intellectual property, but only to the extent such alleged infringement or misappropriation
is directly attributable to Novvi LLC’s adherence to Amyris’s then-approved BioFene manufacturing process licensed
from Amyris as part of the licensed Amyris BioFene Manufacturing Technology and not to any deviation or modification from such
process made by or on behalf of Novvi LLC or a permitted sublicensee of Novvi LLC, other than a deviation or modification made
by Novvi LLC at the written direction of Amyris; or



 


		(vi)	Amyris’s or its Affiliates’ activities
prior to the Effective Date with regard to its use of Base Oils, Additives or Lubricants for the Lubricants Market, including any
sampling of







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such
products by Amyris or its Affiliates to Third Parties prior to the Effective Date (collectively (i)-(vi), each a “Novvi
LLC Third Party Claim”); 


 


provided
that Amyris will not defend, indemnify, or hold harmless Novvi LLC Indemnities under this Section to the extent such Losses and/or
Novvi LLC Third Party Claim is determined to have resulted from the causes described in Section 7.2(i)-(iv).


 


7.2Novvi
LLC’s Indemnification Obligations. Novvi LLC will defend, indemnify, and hold harmless Amyris, its Affiliates and its
and their respective shareholders, directors, officers, employees, and agents and their respective successors, heirs, and permitted
assigns (collectively, “Amyris Indemnitees”) from and against any and all Losses arising from a Third Party’s
claim, action, suit, or demand (or judgments or settlements arising therefrom) against an Amyris Indemnity, in each case to the
extent resulting from:


 


		(i)	any breach by Novvi LLC of this License Agreement;




 


		(ii)	the negligent, reckless, or intentionally
wrongful acts or omissions on the part of any Novvi LLC Indemnitee in performing any activity related to this License Agreement;



 


		(iii)	except as set forth in Section 7.1(iv), Novvi
LLC’s development, making (have made), offer for sale, sale, or import of any Base Oil, Additive, or Lubricant derived from
BioFene, including any claims of product liability or claims of infringement or misappropriation of a Third Party’s intellectual
property; or 



 


		(iv)	except as set forth in Section 7.1(v), Novvi
LLC’s manufacture of BioFene allegedly infringing or misappropriating a Third Party’s intellectual property (collectively
(i)-(iv), each an “Amyris Third Party Claim”); 



 


provided that Novvi LLC will not
defend, indemnify, or hold harmless Amyris Indemnities under this Section to the extent such Losses and/or Amyris Third Party Claim
is determined to have resulted from the causes described in Section 7.1(i)-(vi).


 


7.3Indemnification
Procedures. The Parties’ obligations under Sections 7.1 and 7.2 shall be governed by and contingent upon the following:


 


(a)Notice
of Claim. All indemnification claims in respect of a Novvi LLC Indemnitee or Amyris Indemnitee
shall be made solely by Novvi LLC or Amyris, as applicable (each of Novvi LLC or Amyris in such capacity, the “Indemnified
Party”). Promptly after a Novvi LLC Indemnitee or an Amyris Indemnitee receives notice of a threatened, pending, or actual
Novvi LLC Third Party Claim or Amyris Third Party Claim (a “Third Party Claim”), the applicable Indemnified
Party shall give written notice of the Third Party Claim to the Party to whom that Indemnified Party is entitled to look for indemnification
pursuant to this Article 7 (the “Indemnifying Party”). Such written notice (an “Indemnification Claim
Notice”) shall contain a description of the claim, the nature and amount of such Loss (to the extent that the nature
and amount of such Loss is known at such time), and the basis for indemnification under this Article 7. An Indemnified Party’s
delay in providing, or failure to provide, an Indemnification Claim Notice will not relieve the Indemnifying Party of its obligations
under this Article 7 for the Third Party Claim, except to the extent it can demonstrate that such delay or failure materially adversely
affects the ability of the Indemnifying Party to defend the Third Person Claim, to cure the breach (if applicable) giving rise
to such Third Person Claim, or minimize the applicable Loss. The Indemnified Party shall also furnish promptly to the Indemnifying
Party copies of all papers and official documents received in respect of the Third Party Claim.


 



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(b)Assumption
of Defense. At its option, the Indemnifying Party may assume the defense of the Third Party Claim by giving written notice
to the Indemnified Party within thirty (30) days after receipt of the Indemnification Claim Notice (an “Assumption Notice”).
Such assumption shall not be construed as an acknowledgement of liability or a waiver of any defenses by the Indemnifying Party
(and the Indemnifying Party shall be reimbursed by the Indemnified Party in the case in which the Indemnified Party is not liable
under this Article 7). 


 


(c)Control
of Defense by the Indemnifying Party. Upon giving a timely Assumption Notice to the Indemnified Party, the Indemnifying Party:



 


		(i)	has the exclusive right, at its own expense and by counsel of
its choosing (but who is reasonably satisfactory to the Indemnified Party), conduct and control the defense and the disposition
or, subject to Subsection (d) below, settlement of the Third Party Claim (including all decisions relative to litigation, appeal,
and settlement);



 


		(ii)	will conduct the defense and, if applicable, settlement of such
Third Person Claim in a reasonable and diligent manner;
	 	 	 
	 	(iii)	will
keep the Indemnified Party informed on a reasonable and timely basis as to the status of such Third Party Claim to the extent the
Indemnified Party is not participating in the defense;
	 	 	
	 	(iv)	is
not liable for the fees or expenses of counsel hired by the Indemnified Party in connection with the defense of the Third Party
Claim (except in the case where the interests of the Indemnified Party and Indemnifying Party are sufficiently adverse to prohibit
the representation by the same counsel of both Parties under Applicable Law, ethical rules or equitable principles); and
	 	 	 
	 	(v)	is
not liable for any other expenses subsequently incurred by the Indemnified Party in connection with such defense, other than the
Indemnified Party’s reasonable out-of-pocket costs incurred in cooperating with the Indemnifying Party per Subsection (e)
below.



 




(d)Settlement
by the Indemnifying Party. If an Indemnifying Party has assumed the defense of a Third Party Claim under Subsection (b) above,
the Indemnifying Party may not settle or compromise a Third Party Claim without the prior written consent of the Indemnified Party
(not to be unreasonably withheld, conditioned, or delayed) unless such settlement or compromise (i) involves no payment (whether
by cash, securities or other instrument), assignment, obligation, granting of a license, or admission of fault or wrongdoing by,
or injunctive or other equitable relief against, the Indemnified Party and (ii) the Indemnified Party receives a comprehensive
general release of all claims from the applicable Third Party. In no event will an Indemnifying Party, without the written consent
of the other Party, be entitled to settle any Third Party Claim by granting a license or covenant not to sue under or with respect
to the Patents or other intellectual property rights owned by the other Party. Furthermore, in the case of a Novvi LLC Third Party
Claim under Section 7.1(v), Novvi LLC agrees that, if Amyris has assumed the defense of such Third Party Claim under Subsection
(b) above, Novvi LLC will work together with Amyris in good faith should Amyris reasonably determine that settling such matter
and/or the Parties avoiding additional such Third Party Claims is to modify the BioFene manufacturing process that is both licensed
to Novvi LLC and used by Amyris for its own BioFene manufacturing. 


 


(e)Indemnified
Party’s Cooperation. If an Indemnifying Party has assumed the defense of a Third Party Claim under Subsection (b), the
Indemnified Party shall, and shall cause each of its Novvi


 



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LLC
Indemnitees or Amyris Indemnitees (as applicable), to reasonably cooperate with the Indemnifying Party, mitigate potential Losses,
and furnish such records, information and testimony, provide such witnesses and attend such conferences, discovery proceedings,
hearings, trials and appeals as may be reasonably requested in connection therewith. Such cooperation shall include access during
normal business hours by the Indemnifying Party to, and reasonable retention by the Indemnified Party of, records and information
that are reasonably relevant to such Third Party Claim and making the Indemnified Party and its Novvi LLC Indemnitees or Amyris
Indemnitees (as applicable) available on a mutually convenient basis to provide additional information and explanation of any records
or information provided. In addition, if an Indemnifying Party has assumed the defense of a Third Party Claim under Subsection
(b), the Indemnified Party may employ separate counsel to participate in the defense of such Third Party Claim, but such counsel
will be at the Indemnified Party’s sole expense.    


 


(f)Expenses.
Any reasonable and verifiable costs and expenses incurred by the Indemnified Party in connection with a Third Party Claim and reimbursable
as set forth this Article 7 shall be reimbursed on a calendar quarter basis by the Indemnifying Party, without prejudice to the
Indemnifying Party’s right to contest the Indemnified Party’s right to indemnification and subject to refund in the
event the Indemnifying Party is ultimately held not to be obligated to defend, indemnify, or hold harmless the Indemnified Party
under this Article 7.


 


(g)
Breach by the Indemnifying Party of its Article 7 Obligations. If the Indemnifying Party denies its obligations under
this Article 7, fails to timely provide an Assumption Notice with regard to a Third Party Claim, or fails to diligently defend,
indemnify, and hold harmless such Third Party Claim throughout the period that such claim exists, then its right to defend that
Third Party Claim shall immediately terminate upon written notice from the Indemnified Party, and the Indemnified Party may assume
the defense of, and settle, such claim with counsel of its own choice and on such terms as it deems reasonably appropriate, with
written notice to the Indemnifying Party but without any obligation to obtain the consent of the Indemnifying Party. The Indemnifying
Party will be obligated to indemnify and hold harmless the Indemnified Party for the costs of such defense and settlement if it
is determined that the Indemnifying Party breached its obligations under this Article 7 with regard to such Third Party Claim and
that the Third Party Claim is subject to the indemnification provisions of this Article 7.  


 


7.4Disclaimer
of Consequential Damages. EXCEPT FOR WILLFUL MISCONDUCT, NEITHER PARTY WILL BE LIABLE TO THE OTHER PARTY FOR INDIRECT, INCIDENTAL,
CONSEQUENTIAL, EXEMPLARY OR PUNITIVE OR SPECIAL DAMAGES OF ANY KIND ARISING OUT OF OR IN CONNECTION WITH THIS LICENSE AGREEMENT,
INCLUDING, BUT NOT LIMITED TO, LOST PROFITS, HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY (WHETHER IN CONTRACT, TORT (INCLUDING
NEGLIGENCE), STRICT LIABILITY OR OTHERWISE), EVEN IF SUCH PARTY WAS ADVISED OR OTHERWISE AWARE OF THE LIKELIHOOD OF SUCH DAMAGES
AND REGARDLESS OF ANY NOTICE OF THE POSSIBILITY OF SUCH DAMAGES; PROVIDED, HOWEVER, THAT THE FOREGOING DISCLAIMER
DOES NOT APPLY TO OR LIMIT EITHER PARTY’S INDEMNIFICATION OBLIGATIONS UNDER THIS ARTICLE 7 WITH REGARD TO THIRD PERSON CLAIMS.



 


7.5Insurance.
While a Party’s license(s) under this License Agreement are in effect and for three (3) years thereafter, such Party
shall have and maintain such type and amounts of liability insurance covering its activities under this License Agreement as is
normal and customary in such Party’s industry for parties similarly situated, and such Party shall upon request provide the
other Party a certificate confirming such insurance is in place.


 


 


ARTICLE 8



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DISPUTE RESOLUTION


 


8.1Governing
Law. This License Agreement shall be governed by and construed, interpreted and enforced in accordance with the laws of the
State of New York, without giving effect to the principles of conflicts of law or of choice of law thereof (other than Sections
5-1401 and 5-1402 of the New York General Obligations Law, which shall apply to this License Agreement).
The Parties agree to exclude the application to this License
Agreement of the United
Nations Convention on Contracts for the International Sale
of Goods.


 


8.2Binding
Arbitration.


 


(a)Informal
Resolution. In the event of any dispute between the Parties involving this License Agreement, such dispute shall be governed
by and resolved subject to this Article 8. Notwithstanding anything contained in this License Agreement, the Parties undertake
to use their reasonable efforts to amicably resolve by mutual negotiation of their chief executive officers (or their designees)
any disputes between themselves involving this License Agreement. 


 


(b)Submit
to AAA Arbitration. In case such mutual agreement is not reached under Subsection (a) above within thirty (30) days after submission
of the dispute to the Parties’ chief executive officers (or their designees), either Party, subject to Subsection (i) below
with regard to Patent disputes, may refer the dispute to binding arbitration under the then-existing rules (“Arbitration
Rules”) of the American Arbitration Association (“Arbitration Chamber”), which will exclusively and
finally settle such dispute. The Arbitration Rules are deemed to be incorporated by reference into this License Agreement, except
as such Arbitration Rules may be modified herein or by subsequent mutual agreement by the Parties. The arbitration proceedings
filed based on this License Agreement shall be administered by the Arbitration Chamber. Any such arbitration shall be conducted
in accordance with, and subject in all respect to, the following: For the avoidance of doubt, this Article 8 equally binds all
Parties to this License Agreement, and such Parties hereby agree to submit to and comply with all the terms and conditions of this
Article 8, which shall be in full force and effect irrevocably, and subject to specific performance. Unless otherwise agreed in
writing, the Parties shall continue to diligently perform their respective duties and obligations under this License Agreement
while an arbitral proceeding is pending.


 


(c)Selection
of the Arbitral Tribunal. Each arbitration under this Article 8 will be settled by a panel of three (3) arbitrators. Each Party
shall nominate one arbitrator in accordance with the Arbitration Rules, and the two arbitrators so nominated shall nominate jointly
a third arbitrator, who shall serve as the chair of the arbitral tribunal (“Arbitral Tribunal”), within fifteen
(15) days from the receipt of a communication from the Arbitration Chamber by the two previously nominated arbitrators. If any
arbitrator has not been nominated within the time limits specified herein and/or in the Arbitration Rules, as applicable, such
appointment shall be made by the Arbitration Chamber upon the written request of either Party within fifteen (15) days of such
request. If at any time a vacancy occurs in the Arbitral Tribunal, the vacancy shall be filled in the same manner and subject to
the same requirements as provided for the original appointment to that position.


 


(d)Location
of the Arbitration. The place of arbitrations shall be the city of New York, New York, U.S.A., where the award(s) shall be
rendered, and all arbitrations shall be conducted in English.


 


(e)Arbitration
Decision. An arbitration award shall be final, unappealable and binding on the Parties, their successors and assignees, who
agree to comply with it and spontaneously and expressly



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waive
any form of appeal, except for the request for fraud, correction of material error or clarification of uncertainty, doubt, contradiction
or omission of the arbitration award. If necessary, an arbitration award may be performed in any court that has jurisdiction or
authority over a Party or its assets. The arbitration award will include the distribution of costs, including reasonable attorney’s
fees and reasonable expenses as the Arbitral Tribunal sees fit.


 


(f)Exclusive
Dispute Resolution Process; Exceptions. The Parties are fully aware of all terms and effects of the arbitration provisions
herein agreed upon and irrevocably agree that arbitration hereunder is the only form of resolution of any disputes arising between
themselves involving this License Agreement, except as expressly set forth to the contrary in this Section 8.2. Without prejudice
to the validity of these arbitration provisions, either Party may seek judicial assistance and/or relief, if and when necessary,
for the sole purposes of:


 


		(i)	executing obligations that admit, forthwith, specific performance;




 


		(ii)	obtaining coercive or precautionary measures or procedures of
a preventive, provisional or permanent nature, as security for the arbitration to be commenced or already in course between the
Parties and/or to ensure the existence and efficacy of the arbitration proceeding; or 



 


		(iii)	fraud, correction of material error or clarification of uncertainty,
doubt, contradiction or omission of the arbitration award; or



 


		(iv)	obtaining measures of a mandatory and specific nature; 



 


it being
understood that, upon accomplishment of the mandatory or specific enforcement procedures sought, the dispute shall be returned
to the Arbitral Tribunal to be established or already established, as applicable, full and exclusive authority to decide on all
and any issues, whether related to procedure or merit, which has caused the mandatory or specific enforcement claim, with the respective
judicial proceeding being interrupted until the partial or final decision of the Arbitral Tribunal. The Parties agree that irreparable
damage would occur in the event any provision of this License Agreement was not performed in accordance with the terms hereof and
that the Parties shall be entitled to specific performance of the terms hereof, in addition to any other remedy at law or in equity.


 


For the
measures indicated in (i) through (iv) above, the Parties elect any state or U.S. federal court located in the city of New York,
New York, U.S.A., to the exclusion of any other courts, and the Parties hereby irrevocably submit to the exclusive jurisdiction
of any state or U.S. federal court located within the City of New York, New York, U.S.A. over any such action. The Parties hereby
irrevocably waive, to the fullest extent permitted by Applicable Law, any objection which they may now or hereafter have to the
laying of venue of any such action brought in such court or any defense of inconvenient forum for the maintenance of such action.
The filing of any measure under this Subsection (f) does not entail any waiver to the arbitration under this Article 8 or to the
full jurisdiction of the Arbitral Tribunal.


 


(g)Confidentiality.
The Parties and their respective Representatives, the witnesses, the Arbitral Tribunal, the Arbitration Chamber and its secretariat
agree to treat the existence, content, awards and decisions relating to an arbitration proceeding hereunder, together with all
the materials, information and testimony used therein or created for the purposes thereof, as well as other documents produced
or disclosed by each Party during the arbitration proceeding, as Confidential Information of the other Party, subject to the obligations
and exceptions in Section 5.10.



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(h)Consolidation
with Second Amended and Restated Operating Agreement Arbitrations. In order to facilitate the comprehensive resolution of related
disputes between the Parties under this License Agreement and the Second Amended and Restated Operating Agreement, any or all such
disputes may be brought in a single arbitration under the following circumstances and conditions: If one or more arbitrations are
already pending between the Parties hereunder or under the Second Amended and Restated Operating Agreement and a new dispute arises
between the Parties under any of said agreements or a subsequently filed arbitration is brought between the Parties under any said
agreements, then a Party may request that such new dispute or any subsequently filed arbitration be consolidated into any prior
pending arbitration. Within twenty (20) days of a request to consolidate, the Parties shall select one of the prior pending arbitrations
into which the new dispute or subsequently filed arbitration may be consolidated (“Selected Arbitration”). If
the Parties are unable to agree on the Selected Arbitration within such twenty (20) day period, then the Arbitration Chamber shall
indicate the Selected Arbitration within twenty (20) days of a written request by a Party. If the Arbitration Chamber fails to
indicate the Selected Arbitration within the 20-day time limit indicated above, the arbitration first initiated shall be considered
the Selected Arbitration. The new dispute or subsequently filed arbitration shall be so consolidated, provided that the Arbitral
Tribunal for the Selected Arbitration determines that: (i) the new dispute or subsequently filed arbitration presents significant
issues of law or fact common with those in the Selected Arbitration; (ii) neither Party would be unduly harmed in the new dispute
or in the Selected Arbitration; and (iii) consolidation under these circumstances would not result in undue delay for the Selected
Arbitration. Any such order of consolidation issued by the Arbitral Tribunal shall be final and binding upon the Parties. The Parties
waive any right they may have to appeal or to seek interpretation, revision or annulment of such order of consolidation under the
Arbitration Rules and/or the Applicable Law in any court. The Arbitral Tribunal for the Selected Arbitration into which
a new dispute or subsequently filed arbitration is consolidated shall serve as the Arbitral Tribunal for the consolidated arbitration.


 


(i)Exception
for Patent-related Disputes. In the event that a dispute arises with respect to the inventorship, scope, ownership, validity,
enforceability, revocation or infringement of a Patent and such dispute cannot be resolved by the Parties in accordance with Subsection (a)
above, then, unless otherwise agreed by the Parties in writing, such dispute will not be submitted to arbitration under this Section
8.2, and either Party may initiate litigation solely in a court of competent jurisdiction in the country of issuance of the Patent
that is the subject of the dispute.


 


8.3Service
of Process. Each Party agrees that, in any dispute, claim, action, suit or proceeding between the Parties in connection with
this License Agreement that, per this License Agreement or Applicable Law, may be brought in a court, process may be served on
a Party anywhere in the world, whether within or without the jurisdiction of any such court. Without limiting the foregoing, each
Party agrees that service of process on such Party at the location, and as provided, in Section 10.10 shall be deemed effective
service of process on such Party. Nothing herein shall affect the right of either Party to serve legal process in any other manner
permitted by Applicable Law or at equity. 


 


8.4Waiver
of Jury Trial. WITH RESPECT TO ANY DISPUTE, CLAIM, ACTION, SUIT OR PROCEEDING BETWEEN THE PARTIES IN CONNECTION WITH THIS LICENSE
AGREEMENT THAT, PER THIS LICENSE AGREEMENT OR APPLICABLE LAW, MAY BE BROUGHT IN A COURT, EACH OF THE PARTIES HEREBY IRREVOCABLY
WAIVES AND RELEASES TO THE OTHER ITS RIGHT TO A TRIAL BY JURY AND AGREES THAT IT WILL NOT SEEK A TRIAL BY JURY IN ANY SUCH DISPUTE,
CLAIM, ACTION, SUIT OR PROCEEDING.


 


 


ARTICLE 9



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TERM AND TERMINATION


 


9.1Term of the
License Agreement. The term of this License Agreement shall commence on the Effective Date and shall continue in full force
and effect until the expiration or termination of all licenses granted pursuant to Sections 2.1, 2.2, and 2.3.


 


9.2Initial Term
of the Licenses.


 


(a)Novvi LLC’s
Licenses in Section 2.1. The licenses granted to Novvi LLC in Section 2.1 will be effective as of the Effective Date and will
continue, unless earlier terminated per this Article 9, until (i) with respect to any Know-How in the Amyris Base Technology, the
twentieth (20th) anniversary of the Effective Date and (ii) with respect to each Patent in the Amyris Base Technology,
the twentieth (20th) anniversary of the Effective Date or the expiration or invalidation of the applicable Patent, whichever
is sooner.


 


(b)Novvi LLC’s
License under Section 2.3. If Amyris grants Novvi LLC a license under Section 2.3, then such license will be effective upon
the date Amyris grants it per the terms of Section 2.3 and will continue, unless earlier terminated per this Article 9, until (i)
with respect to any Know-How in the Amyris BioFene Manufacturing Technology, the twentieth (20th) anniversary of the
Effective Date and (ii) with respect to each Patent in the Amyris BioFene Manufacturing Technology, the twentieth (20th)
anniversary of the Effective Date or the expiration or invalidation of the applicable Patent, whichever is sooner.


 


(c)Amyris’s
License in Section 2.2. The license granted to Amyris in Section 2.2 will be effective as of the Effective Date and will continue,
unless earlier terminated per this Article 9, until (i) with respect to any Know-How in the Novvi LLC BioFene Transformation Technology,
the twentieth (20th) anniversary of the Effective Date and (ii) with respect to each Patent in the Novvi LLC BioFene
Transformation Technology, the twentieth (20th) anniversary of the Effective Date or the expiration or invalidation
of the applicable Patent, whichever is sooner.


 


9.3Extend the
Term of Licenses. If a license granted to Novvi LLC in Section 2.1 or under Section 2.3, or to Amyris under Section 2.2, has
not been earlier terminated under this Article 9, the Parties agree to decide, no later than the eighteenth (18th) anniversary
of the Effective Date, whether or not to extend the term of such license(s) set forth in Section 9.2(a)-(c) beyond the twentieth
(20th) anniversary of the Effective Date. If the Parties agree to extend the term of such licenses to Novvi LLC and/or
Amyris, such extension shall be set forth in writing signed by both Parties, but such licenses will still be subject to earlier
termination under this Article 9.


 


9.4Expiration
of a Novvi LLC License. Upon the expiration of the term (as may be extended per Section 9.3) of a license granted to Novvi
LLC in Section 2.1 or under Section 2.3 if such license was not earlier terminated,


 



	 	(i)	such expired
license will immediately cease;
	 	 	 
		(ii)	Novvi LLC will have no rights to or under any intellectual property or Confidential Information
of Amyris, unless, at the time, it continues to have another unexpired and un-terminated license(s) under this License Agreement,
in which case such unexpired and un-terminated license(s) of Novvi LLC will continue unaffected, as will this License Agreement
with regard to such unexpired and un-terminated license(s);



 



    Page 29 of 37


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		(iii)	any sublicense Novvi LLC may have granted an Affiliate or Third Party under the expired license
automatically terminates;



 


		(iv)	Section 2.1 or 2.3 (whichever is applicable to the expired license) and Article 3 (if the expired
license had been granted under Section 2.1) automatically terminate;



 


		(v)	Novvi LLC, if upon such expiration it has no more licenses under this License Agreement, will remain
obligated to perform its obligations in Articles 5, 7, 8, and 10; and



 


		(vi)	Amyris’s license under Section 2.2 will continue unaffected, as will this License Agreement
with regard to such license.



 



9.5Expiration
of Amyris License. Upon the expiration of the term (as may be extended per Section 9.3) of the license granted to Amyris in
Section 2.2,


 



	 	(i)	such expired
license will immediately cease;
	 	 	 
		(ii)	Amyris will have no rights to or under any intellectual property or Confidential Information of
Novvi LLC;



 


		(iii)	any sublicense Amyris may have granted an Affiliate or Third Party under the expired license automatically
terminates;



 


		(iv)	Section 2.2 automatically terminates;



 


		(v)	Amyris will remain obligated to perform its obligations pursuant to this License Agreement; and



 


		(vi)	Novvi LLC’s licenses under Sections 2.1 and 2.3 will continue unaffected, as will this License
Agreement with regard to such licenses.



 



9.6Uncured Material
Breach by Novvi LLC. If Novvi LLC materially breaches this License Agreement and does not cure such breach within sixty (60)
days after receiving written notice from Amyris of such breach, Amyris may, with another written notice to Novvi LLC, immediately
terminate all of the licenses granted to Novvi LLC under this License Agreement. If, per this Section, Amyris terminates Novvi
LLC’s licenses under this License Agreement, then, upon such termination,:


 


		(i)	Novvi LLC will have no rights to or under any intellectual property or Confidential Information
of Amyris;



 


		(ii)	any sublicense Novvi LLC may have granted an Affiliate or Third Party automatically terminates;



 


		(iii)	Sections 2.1 and 2.3 and Article 3 automatically terminate;



 


		(iv)	Novvi LLC will remain obligated to perform its obligations in Articles 5, 7, 8, and 10; and



 


		(v)	Amyris’s license under Section 2.2 will continue unaffected, as will this License







    Page 30 of 37


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Agreement
with regard to such license.


 


Termination under this Section is not Amyris’s
exclusive remedy for a Novvi LLC breach but is in addition to any other rights or remedies Amyris may have under this License Agreement
or Applicable Law for such breach.


 


9.7Uncured Material
Breach by Amyris. If Amyris materially breaches this License Agreement and does not cure such breach within sixty (60) days
after receiving written notice from Novvi LLC of such breach, Novvi LLC may, with another written notice to Amyris, immediately
terminate the license granted to Amyris under this License Agreement. If, per this Section, Novvi LLC terminates Amyris’s
license under this License Agreement, then, upon such termination,:


 


		(i)	Amyris will have no rights to or under any intellectual property or Confidential Information of
Novvi LLC;



 


		(ii)	any sublicense Amyris may have granted an Affiliate or Third Party under the license automatically
terminates;



 


		(iii)	Section 2.2 automatically terminates;



 


		(iv)	Amyris will remain obligated to perform its obligations in Articles 5, 7, 8, and 10; and



 


		(v)	Novvi LLC’s licenses under Sections 2.1 and 2.3 will continue unaffected, as will this License
Agreement with regard to such licenses.



 



9.8Event of
Dissolution of Novvi LLC. Upon the occurrence of an event described in Section 11.03 of the Second Amended and Restated Operating
Agreement that triggers dissolution of Novvi LLC and Novvi LLC is dissolved and wound up:


 


		(i)	all of the licenses granted to Novvi LLC under this License Agreement, if not previously expired
or terminated, will automatically terminate;



 


		(ii)	Novvi LLC will have no rights to or under any intellectual property or Confidential Information
of Amyris;



 


		(iii)	any sublicense Novvi LLC may have granted an Affiliate or Third Party automatically terminates;
and



 


		(iv)	Sections 2.1 and 2.3 and Article 3 automatically terminate (if not previously terminated).



 


9.9Insolvency
Event for Novvi LLC. Upon the occurrence of an Insolvency Event for Novvi LLC:


 


		(i)	all of the licenses granted to Novvi LLC under this License Agreement, if not previously expired
or terminated, will automatically terminate;



 


		(ii)	Novvi LLC will have no rights to or under any intellectual property or Confidential Information
of Amyris;



    Page 31 of 37


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		(iii)	any sublicense Novvi LLC may have granted an Affiliate or Third Party automatically terminates;



 


		(iv)	Sections 2.1 and 2.3 and Article 3 automatically terminate (if not previously terminated or expired);



 


		(v)	Novvi LLC will remain obligated to perform its obligations in Articles 5, 7, 8, and 10; and



 


		(vi)	Amyris’s license under Section 2.2 will continue unaffected per Section 2.6, as will this
License Agreement with regard to such license.



 


9.10Insolvency
Event for Amyris. Upon the occurrence of an Insolvency Event for Amyris:


 


		(i)	the license granted to Amyris under this License Agreement, if not previously expired or terminated,
will automatically terminate;



 


		(ii)	Amyris will have no rights to or under any intellectual property or Confidential Information of
Novvi LLC;



 


		(iii)	any sublicense Amyris may have granted an Affiliate or Third Party under the license automatically
terminates;



 


		(iv)	Section 2.2 automatically terminates (if not previously terminated or expired);



 


		(v)	Amyris will remain obligated to perform its obligations in Articles 5, 7, 8, and 10; and



 


		(vi)	Novvi LLC’s licenses under Sections 2.1 and 2.3 will continue unaffected per Section 2.6,
as will this License Agreement with regard to such licenses.



 



9.11Surviving
Provisions. Notwithstanding anything to the contrary, in the event that this License Agreement expires or is terminated, the
following provisions, and the Parties’ respective rights and obligations under them, will survive such circumstances: Article
1, Sections 5.1, 5.2, 5.3, 5.4, 5.8, and 5.10 (for the time period set forth in Section 5.10), Article 7, Article 8, and Article
10, and this Section.


 


 


ARTICLE 10


 


MISCELLANEOUS


 


10.1Compliance
with Law. With respect to the performance of this License Agreement and the activities contemplated by this License Agreement,
each Party shall comply with all Applicable Laws.


 


10.2No Conflicting
Rights. Neither Party will grant any license, right, or encumbrance to any Affiliate or Third Party that would conflict with
the licenses or rights granted hereunder or enter into any agreement that would impair such Party’s ability to perform its
obligations under this License Agreement.



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10.3Further
Assurances.  After the Effective Date, each of the Parties shall execute and deliver such additional documents, certificates,
and instruments and perform such additional acts, as may be reasonably requested and necessary or appropriate to carry out the
purposes and intent and all of the provisions of this License Agreement and to consummate all of the transactions contemplated
by this License Agreement.



 


10.4Expenses. 
Each Party shall be responsible for and bear all of its own costs and expenses (including but not limited to any attorneys’
fees, accountants’ fees, or financial advisors’ fees or any prior commitment in respect thereof) with regard to the
negotiation and consummation of the transactions contemplated by this License Agreement. 


 


10.5Relationship
of the Parties.  Each Party is an independent contractor relative to the other Party under this License Agreement. This
License Agreement is not a partnership agreement, and nothing in this License Agreement shall be construed to establish a relationship
of co-partners or joint venturers between the Parties.  No employee or representative of a Party, per this License Agreement,
shall have any authority to bind or obligate the other Party or to create or impose any contractual or other liability on the other
Party.


 


10.6No
Third Party Beneficiaries. Except with regard
to the Novvi LLC Indemnitees and Amyris Indemnitees under Article 7 and Total with regard to Section 4.1, all rights, benefits,
and remedies under this Licensee Agreement are solely intended for the benefit of the Parties and their respective permitted successors
and assigns. No Third Party (except Novvi LLC Indemnitees and Amyris Indemnitees with regard to their rights, benefits and remedies
Article 7 and Total with regard to Section 4.1) shall have any rights whatsoever to enforce any obligation contained this License
Agreement, seek a benefit or remedy for any breach, or take any other action relating to this License Agreement under any legal
or equitable theory.


 


10.7Amendments
and Waivers. This License Agreement may be
amended or waived if, and only if, such amendment or waiver is in writing and signed, in the case of an amendment, by all Parties
or, in the case of a waiver, by the Party against whom the waiver is to be effective. No failure or delay by any Party in exercising
any right, power or privilege hereunder (other than a failure or delay beyond a period of time specified herein) shall operate
as a waiver thereof; nor shall any waiver by a Party of any term or condition of this License Agreement in any one or more instances,
be deemed to be or construed as a waiver of the same or any other term or condition of this License Agreement on any future occasion.


 


10.8Assignment.
Other than its sublicensing rights under Section 2.1 and potentially under Section 2.3, Novvi LLC may not assign or delegate,
in whole or in part, this License Agreement or any of its rights or obligations under this License Agreement without the prior
written consent of Amyris, such consent not to be unreasonably withheld. In addition to its sublicense rights under Section 2.2,
Amyris may, without Novvi LLC’s consent, assign or delegate, in whole or in part, this License Agreement or any of its rights
or obligations under this License Agreement to (i) an Affiliate but only while such Affiliate remains an Affiliate and if Amyris
remains responsible for such Affiliate’s performance of the License Agreement, (ii) a buyer of all or substantially all
of Amyris’s assets as long as such buyer delivers a writing expressly agreeing to assume such performance, or (iii) a surviving
entity with whom Amyris is merged as long as such surviving entity delivers a writing expressly agreeing to assume such performance.
Any assignment or delegation or attempted assignment or delegation not in accordance with this Section 10.8 shall be null and
void. This License Agreement shall be binding upon and inure solely to the benefit of the Parties and their permitted successors
and assigns.


 


10.9Severability. 
If any provision of this License Agreement should be held invalid, illegal



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or unenforceable
in any jurisdiction, the Parties shall negotiate in good faith a valid, legal and enforceable substitute provision that most nearly
reflects the original intent of the Parties and all other provisions hereof shall remain in full force and effect in such jurisdiction
and shall be liberally construed in order to carry out the intentions of the Parties as nearly as may be possible. Such invalidity,
illegality or unenforceability shall not affect the validity, legality or enforceability of such provision in any other jurisdiction.
Nothing in this License Agreement shall be interpreted so as to require a Party to violate any Applicable Law.


 


10.10Notices. 
All notices, consents, claims, waivers, requests and other communications hereunder shall be in writing and shall be delivered
in person, sent by overnight courier (e.g., Federal Express), facsimile transmission or posted by registered or certified mail,
return receipt requested, with postage prepaid, to the following address of each Party:


 


If
to Amyris:


 


Amyris,
Inc.


5885
Hollis Street, Suite 100


Emeryville,
CA 94608


Attn:
General Counsel


 


If
to Novvi LLC:


 


Novvi
LLC


5885
Hollis Street


Emeryville,
CA 94608


Attn:
President


 


with
a copy to, but only for such time as Cosan US remains a member of Novvi LLC, (but which shall not constitute notice):


 


Cosan
US, Inc.


2711
Centerville Road, Suite 400


Wilmington,
Delaware 19808


Attn:
President


 


Cosan
Lubrificantes e Especialidades S.A.


Rua
Victor Civita, 77 – Edifício 6 / Bloco 1 – 4o andar


Barra
da Tijuca – Rio de Janeiro – RJ


CEP
22775-905 Brazil


Attn:
Chief Executive Officer


 


or
to such other address or addresses as each Party may from time-to-time designate by notice as provided herein.  Any such notice
shall be deemed given (i) when actually received when so delivered personally or by overnight courier or (ii) if mailed, other
than during a period of general discontinuance or disruption of postal service due to strike, lockout or otherwise, on the fifth
(5th) day after its postmarked date thereof or (iii) if sent by facsimile transmission on the date sent if such day
is a business day or the next following business day if such day is not a business day.  


 


10.11Entire
Agreement.  This License Agreement sets forth all the covenants, promises, agreements, warranties, representations, conditions
and understandings between the Parties and supersedes and terminates all prior agreements and understandings between the Parties
relating to the



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subject
matter hereof.  There are no covenants, promises, agreements, warranties, representations, conditions or understandings, either
oral or written, between the Parties other than as set forth in this License Agreement that relate to the subject matter hereof. 


 


10.12Interpretation. 
When a reference is made in this License Agreement to Articles, Sections, or Subsections, such reference shall be to an Article,
Section, or Subsection to this License Agreement unless otherwise indicated.  The words “include,” “includes,”
and “including” when used herein shall be deemed in each case to be followed by the words “without limitation”
and shall not be construed to limit any general statement that it follows to the specific or similar items or matters immediately
following it.  The headings and captions in this License Agreement are for convenience and reference purposes only and shall
not be considered a part of or affect the construction or interpretation of any provision of this License Agreement.  Words
of any gender include the other gender, and words using the singular or plural number also include the plural or singular number,
respectively.  Each Party acknowledges and agrees it has had the opportunity to draft, review and edit the language of this
License Agreement and that no presumption for or against any Party arising out of drafting all or any part of this License Agreement
will be applied in any controversy, claim or dispute relating to, in connection with or involving this License Agreement. Accordingly,
the Parties hereby waive the benefit of any rule of Applicable Law, including California Civil Code Section 1654 and any successor
or amended statute, or any legal decision that would require that in cases of uncertainty, the language of a contract should be
interpreted most strongly against the party who drafted such language. 


 


10.13Counterparts. 
This License Agreement may be executed in any number of counterparts, each of which shall be deemed an original, but all of which
together shall constitute one and the same instrument. This License Agreement may be executed by facsimile or other electronic
signatures (including exchange of emailed pdf), and such signatures shall be deemed to bind each Party as if they were original
signatures.


 


THIS LICENSE AGREEMENT is hereby executed
effective as of the Effective Date by the authorized representatives of the Parties.


 





	AMYRIS, INC.	 	NOVVI LLC	 
	 	 	 	 	 	 
	/s/ R. Asadorian	 	 	 	 
	 	 	 	 	 
	By:	R. Asadorian	 	By:	 	 
	 	 	 	 	 	 
	Title:	CFO	 	Title:	 	 
	 	 	 	 	 	 
	 	 	 	 	 	 
	 	 	 	 	 	 
	 	 	 	 	 	 
	 	 	 	 	 	 
	 	 	 	By:	 	 
	 	 	 	 	 	 
	 	 	 	Title:	 	 



 


 



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subject
matter hereof.  There are no covenants, promises, agreements, warranties, representations, conditions or understandings, either
oral or written, between the Parties other than as set forth in this License Agreement that relate to the subject matter hereof. 


 


10.12Interpretation. 
When a reference is made in this License Agreement to Articles, Sections, or Subsections, such reference shall be to an Article,
Section, or Subsection to this License Agreement unless otherwise indicated.  The words “include,” “includes,”
and “including” when used herein shall be deemed in each case to be followed by the words “without limitation”
and shall not be construed to limit any general statement that it follows to the specific or similar items or matters immediately
following it.  The headings and captions in this License Agreement are for convenience and reference purposes only and shall
not be considered a part of or affect the construction or interpretation of any provision of this License Agreement.  Words
of any gender include the other gender, and words using the singular or plural number also include the plural or singular number,
respectively.  Each Party acknowledges and agrees it has had the opportunity to draft, review and edit the language of this
License Agreement and that no presumption for or against any Party arising out of drafting all or any part of this License Agreement
will be applied in any controversy, claim or dispute relating to, in connection with or involving this License Agreement. Accordingly,
the Parties hereby waive the benefit of any rule of Applicable Law, including California Civil Code Section 1654 and any successor
or amended statute, or any legal decision that would require that in cases of uncertainty, the language of a contract should be
interpreted most strongly against the party who drafted such language. 


 


10.13Counterparts. 
This License Agreement may be executed in any number of counterparts, each of which shall be deemed an original, but all of which
together shall constitute one and the same instrument. This License Agreement may be executed by facsimile or other electronic
signatures (including exchange of emailed pdf), and such signatures shall be deemed to bind each Party as if they were original
signatures.


 


THIS LICENSE AGREEMENT is hereby executed
effective as of the Effective Date by the authorized representatives of the Parties.


 





	AMYRIS, INC.	 	NOVVI LLC	 
	 	 	 	 	 	 
	 	 	/s/ Jeffrey Brown	 
	 	 	 	 	 
	By:	 	 	By:	Jeffrey
Brown	 
	 	 	 	 	 	 
	Title:	 	 	Title:	President
& CEO	 
	 	 	 	 	 	 
	 	 	 	 	 	 
	 	 	 	 	 	 
	 	 	 	/s/ Jason R. Wells	 
	 	 	 	 	 	 
	 	 	 	By:	Jason R. Wells	 
	 	 	 	 	 	 
	 	 	 	Title:	CTO	 



 


 


 






    Page 36 of 37


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Exhibit A


 


Definition of European Union


 


 


 


		1.	Austria





		2.	Belgium





		3.	Bulgaria





		4.	Croatia





		5.	Cyprus





		6.	Czech Republic





		7.	Denmark





		8.	Estonia





		9.	Finland





		10.	France





		11.	Germany





		12.	Greece





		13.	Hungary





		14.	Ireland





		15.	Italy





		16.	Latvia





		17.	Lithuania





		18.	Luxembourg





		19.	Malta





		20.	Netherlands





		21.	Poland





		22.	Portugal





		23.	Romania





		24.	Slovakia





		25.	Slovenia





		26.	Spain





		27.	Sweden





		28.	United Kingdom





 


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