Exhibit 10.5 

 January 27, 2009 

R. Erdtmann	

Dear Mr. Erdtmann:

		I am pleased to make you an offer to join the Company. The purpose of this letter is to set forth the terms of yourproposed employment with the Company, including your compensation level and benefit entitlements. 

1.	**Employment and Duties.
		      	A.  The Company will employ you as Vice President of Finance, beginning on or about the 29th ofJanuary, and you will accordingly make yourself available on a full-time basis to assume that position on or before such date.  In thatposition, you will report directly to the CEO although this is subject to change at the discretion of the Board of Directors.  

		       	B.  Your duties will include all those reflected on the organization chart. You will perform the duties inherent inyour position in good faith and to the best of your ability and will render all services which may be reasonably required of you in suchposition.  While you are employed with the company, you will devote your full time and effort to the business and affairs of theCompany.  Your principal place of operations will be at the Company's offices located in Sunnyvale, California.  

2.	**Compensation.
			A. Your initial base salary will be at the rate of $175,000 per year.  Your base salary will be subject to adjustment bythe Company's Board of Directors on an annual basis. 

			B.  Your base salary will be paid at periodic intervals in accordance with the Company's payroll practices for salariedemployees.

			C. The Company will deduct and withhold, from the base salary and bonuses payable to youhereunder, any and all applicable Federal, state and local income and employment withholding taxes and any other amounts requiredto be deducted or withheld by the Company under applicable statute or regulation.

3.	**Employee Stock Options.	As soon as possible after you join theCompany as Vice President, you will be granted a stock option to purchase 300,000 shares of Pharmacyclics Common Stock. Theoption will have an exercise price equal to 100% of the fair market value of  Pharmacyclics' Common Stock on the grant date and willhave a maximum term of 10 years, subject to earlier termination upon your cessation of employment with the Company.  The option willbecome exercisable as follows: 50,000 options will be exercisable upon completion of one year of service after your date of hire. Anadditional 100,000 will become exercisable with the achievement of defined goals for the first year. The goals for the calendar year2009 are: $30 Million raised in total funding by outside or current investors and or partners. Product, Internal Programs / ClinicalDelivery Schedules met, as laid out and agreed to by the board in its March 2009 Board Meeting. An established organization,efficiently run, including production goals and controls set up and monitored. The remaining options for the following 3 years ofemployment will also be vesting based on performance and achievement of pre-defined goals. Your goals will be defined prior to eachcalendar year and will be measured against at the end of the year. The vesting per year of employment is set at 50,000 options for theyear 2, 3 and 4 of your employment and will vest with achievement of the yearly goals. All vesting under your option will cease uponyour termination of employment. The remaining terms and conditions of your option will be in accordance with the standard provisionsfor stock option grants under the Company's Stock Option Plan.
		4.	**Expense Reimbursement.  You will be entitled to reimbursement from the Company for allcustomary, ordinary and necessary business expenses incurred by you in the performance of your duties hereunder, provided youfurnish the Company with vouchers, receipts and other details of such expenses within thirty (30) days after they are incurred.
		5.	**Fringe Benefits.  You will be eligible to participate in any group life insurance plan,group medical and/or dental insurance plan, accidental death and dismemberment plan, short-term disability program and otheremployee benefit plans, including the Section 401(k) plan and the Employee Stock Purchase Plan, which are made available toexecutive officers of the Company and for which you otherwise qualify.
6.	**Vacation.  You will accrue paid vacation benefits in accordance with Company policy in effect for executive officers.  
7.	**Restrictive Covenants.  During the period of service as the Executive Vice President for the company:
(i) you will devote your full working time and effort to the performance of your duties; and

(ii) except as agreed in your situation, we understand that from time to time you may have to handle other business affairs, whichwill not conflict or compete in any way with your work at PCYC, this work may end up costing you a maximum of about 10% of youravailable employee full time. Your pay reflects this adjustment already and is approved by the CEO. 

			However, you will have the right to perform such incidental services as are necessary in connection with (a) yourprivate passive investments, (b) your charitable or community activities, and (c) your participation in trade or professional organizations,but only to the extent such incidental services do not interfere with the performance of your services.

		8.	**Proprietary Information.  Upon the commencement of your services as Executive Vice President,you will sign and deliver to the Company the standard-form Proprietary Information and Inventions Agreement required of all keyemployees of the Company.
		9.	**Termination of Employment.
			A.  Your employment pursuant to this agreement will be entirely at will.

			B.  The Company may terminate your employment under this agreement at any time for any reason, with orwithout cause (as defined below), by providing you with at least thirty (30) days prior written notice.  However, such notice requirementwill not apply to the termination of your employment for cause pursuant to subparagraph D below.

			C.  You may terminate your employment under this agreement at any time for any reason upon thirty (30) days priorwritten notice to the Company.

			D.  The Company may at any time, upon written notice, terminate your employment hereunder for cause.  Suchtermination will be effective immediately upon such notice.

			For purposes of this agreement, your employment with the Company will be deemed to have been involuntarilyterminated for cause if your services are terminated by the Company for one or more of the following reasons:

(i) acts of fraud or embezzlement or other intentional misconduct which adversely affects the Company's business, or

(ii) failure to correct any material deficiency in the performance of your services as Executive Vice President within thirty (30) afterwritten notification of such deficiency from the Board, or

(iii) misappropriation or unauthorized disclosure or use of the Company's proprietary information.

		Please indicate your acceptance of the foregoing provisions of this employment agreement by signing the enclosed copyof this agreement and returning it to the Company.

Very truly yours,

						PHARMACYCLICS, INC.

By: /s/ GLENN C. RICE******************