1 Proposed Registration of the New Active Ingredient Momfluorothrin

Proposed Regulatory Action : EPA is proposing to grant an unconditional registration for the new active ingredient, momfluorothrin, formulated as four manufacturing

- use products and five end

- use products. I2L Research USA Inc., on behalf of Sumitomo Chemical Company, and McLaughlin Go rmley King Company requested this action. Momfluorothrin belongs to the synthetic pyrethroid class of chemicals and is a broad spectrum insecticide effective against flying, crawling, and stinging insects and other arthropod pests. The proposed uses for th is new chemical include indoor and outdoor spot and crack

- and

- crevice treatments in residential and commercial settings, including application to indoor perimeters and mattresses to control bed bugs. The five end

- use products are formulated, in combination with previously registered active ingredients, as ready

- to

- use aerosols.

Human Health Risk Assessment : The database submitted to support the assessment of human health risk is complete. The proposed uses are non

- food uses and adequate exposure data are available to assess potential residential and occupational exposure. The Agency is adding a 3X safety fact or based on pharmacokinetic considerations (consistent with other pyrethroids) for infants and children <6 years old. EPA has determined that the proposed residential uses of momfluorothrin will not contribute significantly to or change the overall finding s of the 2011 pyrethroids/pyrethrins
cumulative risk assessment. There are no risk estimates of concern for human health. Estimates of both residential and occupational handler and post

- application risk are well below EPA’s level of concern. Furthermore, a s the proposed uses are non

- food uses, limited in scope, there will be no exposure to momfluorothrin through food or drinking water.

Ecological Risk Assessment : Results from a screening

- level ecological risk assessment indicate low potential for risks to non

targ et organisms. T he environmental fate and ecotoxicity databases are sufficient for assessing the risks associated with the proposed uses. Momfluorothrin is considered practically non

- toxic to birds and mammals. Although momfluorothrin is classified as highly toxic to fish, aquatic invertebrates, and terrestrial invertebrates, predicted exposures from ready

- to

- use aerosol formulations are expected to be spatially restricted to small areas. Thus, risk of adverse effects is
considered low.

Endangered Species : T he proposed uses of momfluorothrin are unlikely to result in direct or indirect adverse effects to listed species of any taxon. Thus, a “ no effect ” determination is made.

Efficacy/Benefits : Momfluorothrin is efficacious against several pests of public health concern, including flies, mosquitoes, wasps, hornets, yellow jackets, roaches, ticks, bed bugs, scorpions, centipedes, and certain species of ants and spiders. Additionally, momfluorothrin has a lower ecological hazard profile relati ve to alternative registered products across several taxa.2

Data Requirements : There are no outstanding data requirements at this time for momfluorothrin. Outdoor use expansions including broadcast applications would trigger additional data requirements

.

Mitigation and Labeling Requirements : To mitigate potential exposure to smaller water bodies in close proximity to treated areas, outdoor applications are limited to spot and crack

- and

- crevice treatments, and product labels prohibit application within 25 feet of water. To reduce risk to insect pollinators, application is prohibited if bees are foraging in treatment areas.