United States Court of Appeals for the Federal Circuit 

2008-1029, -1030, -1031, -1032, -1059 

COHESIVE TECHNOLOGIES, INC., 

Plaintiff-Appellant, 

v. 

WATERS CORPORATION, 

Defendant-Cross Appellant. 

 Robert H. Stier, Jr., Pierce Atwood LLP, of Portland, Maine, argued for plaintiffappellant. With him on the brief were Michael J. Sullivan and Sean L. Sweeney. 

 Wiilliam A. Scofield, Jr., Lahive & Cockfield, LLP, of Boston, Massachusetts, 

argued for defendant-cross appellant. With him on the brief was Sibley P. Reppert. 

 

Appealed from: United States District Court for the District of Massachusetts 

Judge Douglas P. Woodlock 
United States Court of Appeals for the Federal Circuit 

2008-1029, -1030, -1031, -1032, -1059 

COHESIVE TECHNOLOGIES, INC., 

Plaintiff-Appellant, 

v. 

WATERS CORPORATION, 

Defendant-Cross Appellant. 

Appeal from the United States District Court for the District of Massachusetts in case 

nos. 98-CV-12308, 99-CV-11528, and 01-CV-12307, Judge Douglas P. Woodlock. 

__________________________ 

DECIDED: October 7, 2008 

__________________________ 

Before MAYER, LINN, and PROST, Circuit Judges. 

Opinion for the court filed by Circuit Judge LINN. Dissenting opinion filed by Circuit 

Judge MAYER. 

LINN, Circuit Judge. 

This is a patent infringement case. Cohesive Technologies, Inc. (“Cohesive”) 

brought three related actions accusing Waters Corporation (“Waters”) of infringing U.S. 

Patent No. 5,772,874 (the “’874 patent”) and U.S. Patent No. 5,919,368 (the “’368 

patent”). In the first action, No. 98-CV-12308, Cohesive accused Waters’s 30 μm Oasis 

high-performance liquid chromatography (“HPLC”) columns (the “30 μm columns”) of 

infringing the ’874 patent. See Cohesive Techs., Inc. v. Waters Corp., 526 F. Supp. 2d 

84, 88 (D. Mass. 2007). In the second action, No. 99-CV-11528, Cohesive accused the 

same 30 μm columns of infringing the ’368 patent. See id. In the third action, No. 01-
CV-12307, Cohesive accused Waters’s 25 μm Oasis HPLC columns (the “25 μm 

columns”) of infringing both patents. See id. 

A jury in the first action found that the ’874 patent was not invalid, and that the 

30 μm columns infringed the ’874 patent. See id. The district court then held a 

combined bench trial and hearing on damages, willful infringement, and inequitable 

conduct in the first action, and on preliminary injunction and summary judgment motions 

in the second and third actions. The district court entered judgment in favor of Cohesive 

in the first action, granted Cohesive’s motion for summary judgment of infringement and 

no invalidity in the second action, and awarded damages. Id. at 126. However, in the 

third action, the district court granted Waters’s motion for summary judgment of 

noninfringement, concluding that the 25 μm products did not infringe either patent. Id. 

Both parties appeal numerous aspects of the judgment. 

As to the 30 μm products, we conclude that the district court correctly construed 

the term “rigid” and properly denied Waters’s motion for judgment of noninfringement as 

a matter of law. We further conclude that the district court committed no clear error in 

concluding that Waters failed to prove the deceptive intent necessary to sustain its claim 

of inequitable conduct. However, we agree with Waters that the district court was 

wrong to enter judgment as a matter of law on anticipation without submitting the issue 

to the jury. 

As to the 25 μm products, we disagree with the district court’s construction of 

“greater than about 30 μm.” Under the correct construction, Waters was not entitled to 

summary judgment of no literal infringement. The district court was, however, correct to 

2008-1029, -1030, -1031, -1032, -1059 2
grant Waters’s motion for summary judgment of no infringement under the doctrine of 

equivalents, though not for the reasons that the district court articulated. 

As to damages, because the district court incorrectly considered the 25 μm 

product as an acceptable noninfringing substitute, and because it is unclear whether the 

other available product, standing alone, would have been an acceptable substitute, we 

vacate the district court’s judgment that Cohesive was not entitled to lost profits and 

remand for reconsideration by the district court in the first instance. We find no clear 

error in the district court’s conclusion that Waters’s infringement was not willful. Finally, 

we decline Cohesive’s request to assign this matter to a different district court judge on 

remand. Accordingly, we affirm-in-part, reverse-in-part, vacate-in-part, and remand. 

I. BACKGROUND 

The ’874 and ’368 patents both relate to HPLC. HPLC is a process for 

separating, identifying, and measuring compounds contained in a liquid. 

Pharmaceutical companies often use HPLC in drug testing to separate absorbed 

compounds from blood. In HPLC, a liquid containing the compounds to be measured is 

passed under pressure through a packed column of chromatographically active 

particles. See ’874 patent col.1 ll.24-28. Because the different molecular components 

in the liquid have different affinities for the particles in the column, each component is 

extracted from the liquid at a different rate and, therefore, at a different location along 

the column. See id. col.1 ll.28-32. The effectiveness of HPLC at separating molecules 

from the liquid depends on several variables, including the size and structure of the 

particles in the column. See id. col.2 ll.3-19. 

The ’368 patent issued from a divisional application of the application that 

resulted in the ’874 patent, and the patents share the same specification. Cohesive 

2008-1029, -1030, -1031, -1032, -1059 3
asserted claims 1, 3, 7, 9, 15, 16, and 20 of the ’874 patent and claims 1, 3, and 8 of the 

’368 patent. See Cohesive, 526 F. Supp. 2d at 107. Claim 1 of the ’874 patent recites: 

Chromatography apparatus comprising, in combination, 

a chromatographic body formed as a substantially uniformly 

distributed multiplicity of rigid, solid, porous particles with 

chromatographically active surfaces, said particles having average 

diameters of greater than about 30 μm, the interstitial volume 

between said particles being not less than about 45% of the total 

volume of said column; and 

means for loading said surfaces with at least one solute that is 

reactive with said surfaces, by flowing a liquid mixture containing 

said solute through said body at a velocity sufficient to induce flow 

of said mixture within at least a substantial portion of said interstitial 

volume at a reduced velocity greater than about 5,000. 

’874 patent col.20 ll.20-34. Each of the asserted claims requires essentially the same 

two key limitations at issue in this appeal: particles that are “rigid” and have average 

diameters “greater than about 30 μm.” See id. col.20 ll.38-42, 54-56, 60-65 (claims 3, 7, 

and 9 depending from claim 1); id. col.21 l.36-col.22 l.8 (claim 15 requiring “rigid solid 

particles” having “substantially uniform mean diameters of not less than about 30 μm”); 

id. col.22 ll.9-21 (claim 16 requiring “rigid, solid, porous particles” with “substantially 

uniform average diameters in the range between about 30 to about 500 μm”); id. col.22 

ll.33-35 (claim 20 depending from claim 16); ’368 patent col.20 ll.14-28 (claim 1 

requiring step of “packing . . . rigid, solid, porous particles” with “average diameters of 

not less than about 30 μm”); id. col.20 ll.32-36, 53-56 (claims 3 and 8 depending from 

claim 1).1

 

 1

 Although “greater than” and “between” 30 μm and a larger number would 

not encompass exactly 30 μm, while “not less than” 30 μm would, this distinction is not 

relevant for our analysis in this case. 

2008-1029, -1030, -1031, -1032, -1059 4
Cohesive brought its first infringement action against Waters in 1998, alleging 

that the 30 μm columns infringed the ’874 patent. In 1999, while the first action was 

pending, the ’368 patent issued. Cohesive then filed a second infringement action 

against Waters, asserting that use of the same 30 μm columns infringed the method 

claims of the ’368 patent. 

In 2001, the district court held a sixteen-day jury trial in the first action. During 

trial, Waters alleged and presented evidence that the claims of the ’874 patent were 

anticipated by seven separate prior art references. Waters also alleged that the claims 

of the ’874 patent were obvious, both in light of each reference independently, and in 

light of various combinations of the references. Over Waters’s objection, the district 

court chose not to submit anticipation to the jury, because Waters had alleged 

obviousness, and the district court “[thought] of anticipation as being a subset of 

obviousness.” J.A. 5710. Accordingly, the district court sua sponte entered a directed 

verdict in favor of Cohesive, finding that the ’874 patent was not anticipated. Cohesive, 

526 F. Supp. 2d at 89. 

The jury returned a verdict finding that the 30 μm columns infringed the ’874 

patent and that the ’874 patent was not obvious. By the time of the verdict, Waters had 

stopped selling the 30 μm columns, and instead was selling a replacement product with 

smaller particles—the 25 μm columns. Cohesive then filed its third infringement action, 

alleging that the replacement 25 μm columns infringed both the ’874 and the ’368 

patents. Cohesive moved for a preliminary injunction against the 25 μm columns. 

The district court held a combined bench trial and hearing in 2002. At that 

proceeding, the court heard evidence and argument on the issues of inequitable 

2008-1029, -1030, -1031, -1032, -1059 5
conduct, willful infringement, and damages in the first case. Id. at 88. The district court 

also considered the parties’ cross-motions for summary judgment in the second case, 

concerning whether those same 30 μm columns infringed the ’368 patent. Id. at 89. 

Additionally, at the request of the district court, Cohesive presented its motion for a 

preliminary injunction in the third case (concerning the replacement 25 μm columns) in 

the form of a motion for summary judgment, and Waters made an oral cross-motion for 

summary judgment of noninfringement at the hearing. 

Five years later, the district court entered a memorandum and order disposing of 

all issues in all three cases. In the first case, concerning infringement of the ’874 patent 

by the 30 μm columns, the district court: (1) denied Waters’s post-trial motions for 

judgment as a matter of law on infringement and invalidity, id. at 95; (2) found that 

Waters had failed to meet its burden to prove inequitable conduct, id. at 103; and 

(3) found that Waters’s infringement was not willful, id. at 106-07. In the second case, 

concerning infringement of the ’368 patent by the 30 μm columns, on cross-motions for 

summary judgment, the district court: (1) granted Cohesive’s motion for summary 

judgment of direct and indirect infringement, id. at 112; and (2) granted Cohesive’s 

motion for summary judgment of no invalidity, id. at 113. In the third case, concerning 

infringement of both patents by the 25 μm columns, the district court granted summary 

judgment of noninfringement in favor of Waters, finding that the 25 μm columns did not 

meet, either literally or by equivalents, the claim limitations requiring particle size greater 

than “about 30 μm.” Id. at 116. Finally, as to damages, the district court held that 

Cohesive was not entitled to lost profits as a matter of law, id. at 121, and ordered 

payment of a reasonable royalty on sales of the 30 μm columns, id. at 125. 

2008-1029, -1030, -1031, -1032, -1059 6
Cohesive timely appealed on the issues of: (1) claim construction of the term 

“about 30 μm”; (2) summary judgment of noninfringement by the 25 μm columns; (3) 

lost profits; (4) willful infringement; and (5) enhanced damages. Cohesive also 

requested that the case be assigned to a different district judge on remand. Waters 

timely cross-appealed on the issues of: (1) claim construction of the term “rigid”; (2) 

denial of judgment as a matter of law of noninfringement by the 30 μm columns; (3) 

grant of judgment as a matter of law on anticipation; and (4) inequitable conduct. We 

have jurisdiction pursuant to 28 U.S.C. § 1295(a)(1). 

II. DISCUSSION 

A. The 30 μm Columns 

We first address whether the district court properly concluded that the ’874 patent 

was infringed by the 30 μm columns, not invalid, and not unenforceable. 

1. Claim Construction 

Waters challenges the district court’s construction of the term “rigid,” which is 

common to all asserted claims. The district court construed “rigid” to mean “an object’s 

capacity to maintain substantially zero changes in density and volume under packing 

pressure of at least about 5000 psi and as a consequence substantially to resist plastic 

deformation under such pressure.” Cohesive, 526 F. Supp. 2d at 89. The district court 

construed “rigid” so that it did not “exclude polymeric particles (as opposed to the 

monomeric particles referred to in the preferred embodiment of the ’874 patent).” Id. 

Waters argues that the failure to exclude polymeric particles in the construction of “rigid” 

was error, because, during prosecution, Cohesive disclaimed polymeric particles as not 

being rigid. 

2008-1029, -1030, -1031, -1032, -1059 7
Claim construction is an issue of law, Markman v. Westview Instruments, Inc., 52 

F.3d 967, 970-71 (Fed. Cir. 1995) (en banc), that we review de novo, Cybor Corp. v. 

FAS Techs., Inc., 138 F.3d 1448, 1456 (Fed. Cir. 1998) (en banc). We determine the 

ordinary and customary meaning of undefined claim terms as understood by a person of 

ordinary skill in the art at the time of the invention, using the methodology in Phillips v. 

AWH Corp., 415 F.3d 1303, 1312-19 (Fed. Cir. 2005) (en banc). “[T]he court looks to 

those sources available to the public that show what a person of skill in the art would 

have understood disputed claim language to mean. Those sources include the words of 

the claims themselves, the remainder of the specification, the prosecution history, and 

extrinsic evidence concerning relevant scientific principles, the meaning of technical 

terms, and the state of the art.” Id. at 1314 (internal quotation marks and citations 

omitted). 

Here, there is no argument that the ordinary meaning of the word “rigid” itself 

requires that a particle be monomeric, rather than polymeric. Likewise, although the 

embodiments of the invention described in the specification all disclose only monomeric 

particles, see, e.g., ’874 patent col.13 ll.29-32, col.14 l.58, col.18, l.21, those 

embodiments cannot limit the otherwise broad claim term “rigid.” See Phillips, 415 F.3d 

at 1323 (“[A]lthough the specification often describes very specific embodiments of the 

invention, we have repeatedly warned against confining the claims to those 

embodiments.”). 

Waters argues, however, that Cohesive disclaimed polymeric particles during 

prosecution. The examiner rejected the claims of the ’874 patent as anticipated by or 

obvious over U.S. Patent No. 5,019,270, issued to Noubar B. Afeyan et al. (“Afeyan”). 

2008-1029, -1030, -1031, -1032, -1059 8
In response, Cohesive argued that, unlike Afeyan, the claims required “truly rigid” 

particles. J.A. 418. Additionally, Cohesive submitted to the examiner the declaration of 

chromatography expert George Guiochon, pursuant to 35 C.F.R. § 1.132. In his 

declaration, Guiochon distinguished between the particles in the claimed invention and 

the particles described in Afeyan: 

While Afeyan et al mention that they desire their particles to be rigid 

solids, such comment can be read best in the light of their teachings . . . 

that mention only polymeric materials such as divinylbenzene and the like. 

Such polymeric material cannot be expected to maintain the requisite 

rigidity to withstand the pressure required to obtain a reduced velocity of 

5000 or higher through a chromatographic column with particles of the 

diameter disclosed by Afeyan et al, so cannot be considered to be a 

teaching of rigid solid particles within the meaning of the claims . . . . 

J.A. 430. Waters contends that the Guiochon declaration resulted in a disclaimer of 

“polymeric material” as not “rigid” within the meaning of the claims. 

“[A] patentee may limit the meaning of a claim term by making a clear and 

unmistakable disavowal of scope during prosecution.” Computer Docking Station Corp. 

v. Dell, Inc., 519 F.3d 1366, 1374 (Fed. Cir. 2008) (quoting Purdue Pharma L.P. v. Endo 

Pharms., Inc., 438 F.3d 1123, 1136 (Fed. Cir. 2006)). In this case, the Guiochon 

declaration does not distinguish the Afeyan particles because they are polymeric; 

instead, it distinguishes the particular polymeric materials taught in Afeyan—

“divinylbenzene and the like”—because “[s]uch polymeric materials” are not sufficiently 

rigid when exposed to the relevant level of pressure. The Guiochon declaration may, 

therefore, be a clear and unmistakable disavowal of the particular particles used in 

Afeyan, but it is not a disavowal of all polymeric particles. 

Waters argues further that, even if the prosecution history cannot be read to have 

disclaimed all polymeric particles, it nonetheless disclaimed the particular type of 

2008-1029, -1030, -1031, -1032, -1059 9
polymeric particles used in the accused 30 μm columns. We disagree. The polymeric 

particles disclaimed in the Guiochon declaration were “divinylbenzene and the like.” 

J.A. 430. The Afeyan patent that the Guiochon declaration distinguishes describes the 

composition of the particles as follows: 

The particles are fabricated from polymers such as, for example, styrene 

cross-linked with divinylbenzene, or various related copolymers including 

such materials as p-bromostyrene, p-styryldiphenylphosphine, p-amino 

sytrene, vinyl chlorides, and various acrylates and methacrylates, 

preferably designed to be heavily cross-linked and derivatizable, e.g., 

copolymerized with a glycidyl moiety or ethylenedimethacrylate. 

Afeyan col.16 l.67-col.17 l.7. By contrast, the particles in the 30 μm columns are 

copolymers of divinylbenzene and n-vinylpyrrolidone. A copolymer of divinylbenzene 

and n-vinylpyrrolidone is not one of the polymers described in Afeyan and was not 

specifically disclaimed in the Guiochon declaration. 

Waters argues that the specific disclaimer of divinylbenzene should suffice to 

disclaim the polymers in the particles of the 30 μm columns, because those particles are 

“made from 80% divinylbenzene.” Br. of Defendant-Cross Appellant Waters Corp. at 

42. But Waters ignores the fact that a divinylbenzene molecule alone and a copolymer 

containing 80% divinylbenzene are different chemical compounds, with different 

properties—including different rigidities. By analogy, if a patentee disclaims “flammable 

substances like hydrogen” during prosecution, the patentee has not disclaimed the 

nonflammable compound H2O, just because it is two-thirds hydrogen. 

In sum, we agree with the district court that the proper construction of “rigid” in 

the asserted claims does not require that the particles be monomeric. We affirm the 

district court’s construction of “rigid” as “an object’s capacity to maintain substantially 

2008-1029, -1030, -1031, -1032, -1059 10
zero changes in density and volume under packing pressure of at least about 5000 psi 

and as a consequence substantially to resist plastic deformation under such pressure.” 

2. Infringement 

Waters argues that the district court erred by denying it judgment as a matter of 

law, because the evidence was insufficient to prove infringement even under the district 

court’s claim construction. “The grant or denial of a motion for judgment as a matter of 

law is a procedural issue not unique to patent law, reviewed under the law of the 

regional circuit in which the appeal from the district court would usually lie.” Summit 

Tech., Inc. v. Nidek Co., 363 F.3d 1219, 1223 (Fed. Cir. 2004). The First Circuit 

reviews the district court’s grant or denial of judgment as a matter of law de novo. 

Espada v. Lugo, 312 F.3d 1, 2 (1st Cir. 2002); Larch v. Mansfield Mun. Elec. Dept., 272 

F.3d 63, 67 (1st Cir. 2001). We therefore consider whether the evidence, when viewed 

in the light most favorable to Cohesive, would permit a reasonable jury to find in favor of 

Cohesive on any permissible claim or theory. Larch, 272 F.3d at 67. 

Waters argues that the evidence at trial was insufficient to permit a reasonable 

jury to conclude that the particles of the 30 μm columns were rigid. The district court’s 

construction of “rigid” required that the particles: (1) “maintain substantially zero 

changes in density and volume under packing pressure of at least about 5000 psi”; and 

(2) “substantially resist plastic deformation under such pressure.” At trial, Cohesive’s 

expert gave his understanding of the terms “substantially zero changes in density and 

volume,” and “substantially resist plastic deformation.” He further testified that he had 

tested the particles of the 30 μm columns by packing them at 5000 psi, that he observed 

“substantially zero changes in density and volume,” and that the particles did not 

“exhibit any plastic deformation.” J.A. 1463-64. Thus, in response to the question, “If 

2008-1029, -1030, -1031, -1032, -1059 11
rigid means an object’s capacity to maintain substantially zero changes in density and 

volume, under a packing pressure of at least about 5,000 psi, and as a consequence, 

substantially to resist plastic deformation under such pressure, do the Waters’ particles 

qualify as rigid?,” Cohesive’s expert answered, “Yes, they do.” J.A. 1462. This is 

sufficient evidence to permit a reasonable jury to conclude that the 30 μm columns were 

rigid. The district court therefore properly denied Waters’s motion for judgment as a 

matter of law of noninfringement. 

3. Invalidity 

Waters argues that the district court erred by granting a directed verdict—i.e., 

judgment as a matter of law—for Cohesive on the issue of anticipation, rather than allow 

the jury to decide the issue. “In reviewing the district court’s ruling, we apply the same 

standards as the district court, meaning that we examine the evidence and all fair 

inferences in the light most favorable to [Waters] and may not consider the credibility of 

witnesses, resolve conflicts in testimony, or evaluate the weight of the evidence.” 

Guilloty Perez v. Pierluisi, 339 F.3d 43, 50 (1st Cir. 2003) (internal quotation marks and 

citations omitted). If a reasonable jury could have found that any of the asserted 

references anticipated the patent, then judgment as a matter of law was improper. See

Wilson v. Moreau, 492 F.3d 50, 52 (1st Cir. 2007); see also Guilloty Perez, 399 F.3d at 

50 (“If we conclude that ‘fair-minded persons could draw different inferences from the 

evidence presented at trial, the matter is for the jury,’ and judgment as a matter of law 

was improperly granted.” (quoting Espada, 312 F.3d at 2)). 

The circumstances that led to the grant of judgment as a matter of law in this 

case were unusual. At a charge conference near the end of trial, the district court 

indicated that it did not intend to charge the jury on anticipation. Specifically, after 

2008-1029, -1030, -1031, -1032, -1059 12
reviewing Waters’s evidence and argument on anticipation and obviousness, the district 

court concluded that “the contentions that the defendant is making [are] best captured 

by obviousness,” rather than anticipation. J.A. 2654. The district court commented that, 

“[u]nder a strict reading, [it did not] see the proof of anticipation in any of the prior art 

publications,” that Waters’s anticipation case was “iffy,” and that its “gut response is that 

none of [the prior art references] are winners.” J.A. 5680, 5704, 5720. Moreover, the 

district court commented that declining to charge on anticipation would not cause “any 

real harm to the defendant,” and would not “make very much difference because it 

comes in in obviousness” J.A. 5680, 5703. The district court expressly stated that it did 

not understand, as a matter of “strategic judgment,” why a defendant “would want [a] 

charge on anticipation when they get one on obviousness.” J.A. 5719, 5717. The 

district court concluded that it could not “find here that the requirements of anticipation 

have been met” in the submitted prior art references, and it therefore directed a verdict 

of no anticipation. J.A. 2654. 

The district court erred by granting judgment as a matter of law on the issue of 

anticipation before the jury was allowed to consider the claim. The district court did not 

make a finding that no reasonable jury could conclude that the asserted references 

anticipated. Rather, the district court itself characterized the anticipation case as “iffy.” 

An “iffy” anticipation case, however, does not foreclose a favorable verdict. See Fed. R. 

Civ. P. 50 (requiring that the court find “that a reasonable jury would not have a legally 

sufficient evidentiary basis” to find for a party before granting judgment as a matter of 

law). 

2008-1029, -1030, -1031, -1032, -1059 13
Moreover, the district court was wrong to conclude that granting judgment as a 

matter of law on anticipation would not harm Waters, simply because the jury had the 

opportunity to consider the same references for purposes of obviousness. Despite the 

often quoted maxim that anticipation is the “epitome of obviousness,” In re Kalm, 378 

F.2d 959, 962 (CCPA 1967), novelty under 35 U.S.C. § 102 and nonobviousness under 

35 U.S.C. § 103 are separate conditions of patentability and therefore separate 

defenses available in an infringement action. See 35 U.S.C. § 282 (2000); Jones v. 

Hardy, 727 F.2d 1524, 1529 (Fed. Cir. 1984) (“[T]hough anticipation is the epitome of 

obviousness, [they] are separate and distinct concepts.”); see also Mendenhall v. 

Cedarapids, Inc., 5 F.3d 1557, 1563 (Fed. Cir. 1993) (holding that verdict of 

nonobviousness was not inconsistent with verdict of anticipation by prior public use, 

despite “legal homily” that anticipation is the epitome of obviousness); In re Meyer, 599 

F.2d 1026, 1031 (CCPA 1979) (holding that rejection under § 102 was new ground 

following previous rejection under § 103, despite maxim that “anticipation is the epitome 

of obviousness”). 

While it is commonly understood that prior art references that anticipate a claim 

will usually render that claim obvious, it is not necessarily true that a verdict of 

nonobviousness forecloses anticipation. The tests for anticipation and obviousness are 

different. See, e.g., Duro-Last, Inc. v. Custom Seal, Inc., 321 F.3d 1098, 1107-08 (Fed. 

Cir. 2003) (“Succinctly put, the various unenforceability and invalidity defenses that may 

be raised by a defendant—inequitable conduct, the several forms of anticipation and 

loss of right under § 102, and obviousness under § 103—require different elements of 

proof.”) Obviousness can be proven by combining existing prior art references, while 

2008-1029, -1030, -1031, -1032, -1059 14
anticipation requires all elements of a claim to be disclosed within a single reference. 

Compare MEHL/Biophile Int’l Corp. v. Milgraum, 192 F.3d 1362, 1365 (Fed. Cir. 1999) 

(“To anticipate, a single reference must teach every limitation of the claimed 

invention.”), with Scripps Clinic & Research Found. v. Genentech, Inc., 927 F.2d 1565, 

1577 (Fed. Cir. 1991) (“If it is necessary to reach beyond the boundaries of a single 

reference to provide missing disclosure of the claimed invention, the proper ground is 

not § 102 anticipation, but § 103 obviousness.”). Moreover, obviousness requires 

analysis of secondary considerations of nonobviousness, while secondary 

considerations are not an element of a claim of anticipation. Compare King Instrument 

Corp. v. Otari Corp., 767 F.2d 853, 857 (Fed. Cir. 1985) (“In a § 103 obviousness 

analysis, Graham [v. John Deere Co., 383 U.S. 1 (1966)] requires that the trier assess 

certain underlying facts: (1) the scope and content of the prior art, (2) the level of 

ordinary skill in the art, (3) the differences between the claimed invention and the prior 

art, and (4) the so-called ‘secondary considerations.’”), with Hakim v. Cannon Avent 

Group, PLC, 479 F.3d 1313, 1319 (Fed. Cir. 2007) (“‘Anticipation’ means that the 

claimed invention was previously known, and that all of the elements and limitations of 

the claim are described in a single prior art reference.”). And although anticipation can 

be proven inherently, proof of inherent anticipation is not the same as proof of 

obviousness. See Perricone v. Medicis Pharm. Corp., 432 F.3d 1368, 1375 (Fed. Cir. 

2005) (“[A] prior art reference without express reference to a claim limitation may 

nonetheless anticipate by inherency.”); Trintec Indus., Inc. v. Top-U.S.A. Corp., 295 

F.3d 1292, 1296 (Fed. Cir. 2002) (“[O]bviousness is not inherent anticipation.”). Thus, 

2008-1029, -1030, -1031, -1032, -1059 15
“it does not follow that every technically anticipated invention would also have been 

obvious.” In re Fracalossi, 681 F.2d 792, 796 (CCPA 1982) (Miller, J., concurring).2

A court cannot refuse to submit the issue of anticipation to the jury simply 

because the accused infringer has also asserted an obviousness defense. It is for the 

litigants—not the court—to make the strategic decision as to whether to assert one, 

both, or neither of these defenses in a jury trial. An accused infringer that introduces a 

prior art reference and makes a non-frivolous argument that “each and every limitation 

of a claim is found, expressly or inherently, in [that] single prior art reference” generally 

 2

 The dissent claims categorically that “every anticipated claim is obvious.” 

Post at 3. But this is not correct. Consider, for example, a claim directed toward a 

particular alloy of metal. The claimed metal alloy may have all the hallmarks of a 

nonobvious invention—there was a long felt but resolved need for an alloy with the 

properties of the claimed alloy, others may have tried and failed to produce such an 

alloy, and, once disclosed, the claimed alloy may have received high praise and seen 

commercial success. Nevertheless, there may be a centuries-old alchemy textbook 

that, while not describing any metal alloys, describes a method that, if practiced 

precisely, actually produces the claimed alloy. While the prior art alchemy textbook 

inherently anticipates the claim under § 102, the claim may not be said to be obvious 

under § 103. 

This is precisely why our precedent has rejected reliance on the “legal homily” 

that “anticipation is the epitome of obviousness.” Mendenhall, 5 F.3d at 1563. We have 

expressly upheld a jury verdict of anticipation under § 102(b), even when the same jury 

found the patent nonobvious under § 103. Id. Though the dissent argues that a “long 

line of precedent” supports its argument that every anticipated claim is obvious, not a 

single one of the cases it cites actually holds that the “epitome” maxim precludes a jury 

from finding a patent invalid under § 102, simply because it is nonobvious under § 103. 

See Johns Hopkins Univ. v. Cellpro, Inc., 152 F.3d 1342, 1357 n.21 (Fed. Cir. 1998) 

(remarking in footnote that trial court did not err in allowing parties to present argument 

on anticipation during trial on obviousness); Connell v. Sears, Roebuck & Co., 722 F.2d 

1542, 1548 (Fed. Cir. 1983) (prefacing quoted discussion of relationship between 

anticipation and obviousness with “it is never necessary to so hold”); Fracalossi, 6 F.2d 

at 794 (addressing whether specific anticipation rejection was sufficient evidentiary 

support for obviousness rejection); In re Pearson, 494 F.2d 1399, 1402 (CCPA 1974) 

(affirming § 103 rejection when § 102 rejection would also have been appropriate); In re 

Kalm, 378 F.2d 959, 963 (CCPA 1967) (reversing anticipation rejection). We cannot 

conclude—as the dissent’s reasoning implies—that the novelty requirement of § 102 is 

mere surplussage, subsumed by the nonobviousness requirement of § 103. 

2008-1029, -1030, -1031, -1032, -1059 16
is entitled to have anticipation decided by the finder of fact. See Planet Bingo, LLC v. 

GameTech Int’l, Inc., 472 F.3d 1338, 1346 (Fed. Cir. 2006). That is precisely what 

Waters did in this case. We therefore reverse the district court’s grant of judgment as a 

matter of law on the issue of anticipation, and remand for further proceedings consistent 

with this opinion. 

4. Inequitable Conduct 

Waters argues that the district court clearly erred by failing to find the deceptive 

intent necessary to sustain a finding of inequitable conduct and erroneously applied a 

“but for” test in determining materiality. “We review the district court’s findings on the 

threshold issues of materiality and intent for clear error. . . . We review the ultimate 

decision regarding inequitable conduct for abuse of discretion.” Cargill, Inc. v. Canbra 

Foods, Ltd., 476 F.3d 1359, 1364-65 (Fed. Cir. 2007). 

Waters argued to the district court that Cohesive committed inequitable conduct 

by submitting the Guiochon declaration but failing to disclose to the United States 

Patent and Trademark Office (the “Patent Office”) that Guiochon did not believe that the 

invention generated “turbulent flow” as distinguished from “laminar” or “smooth” flow. 

Cohesive, 526 F. Supp. 2d at 95 & n.2. Cohesive admitted that its inventors believed 

that the flow generated by the invention of the ’874 and ’368 patents was best 

characterized as “turbulent” and that Guiochon disagreed. Id. at 99. However, 

Cohesive argued that its prosecuting attorney did not believe this distinction to be 

material, because the term “turbulent flow” does not appear in any of the claims of either 

patent and is not defined in the specification. Id. The district court “credit[ed] 

Cohesive’s testimony that it did not believe Guiochon’s definitional distinction was 

2008-1029, -1030, -1031, -1032, -1059 17
material to the ultimate conclusion of his declaration” and accordingly found no intent to 

deceive the Patent Office. Id. 

“With regard to the deceptive intent prong [of inequitable conduct], we have 

emphasized that ‘materiality does not presume intent, which is a separate and essential 

component of inequitable conduct.’” Star Scientific, Inc. v. R.J. Reynolds Tobacco Co., 

537 F.3d 1357, 1366 (Fed. Cir. 2008) (quoting GFI, Inc. v. Franklin Corp., 265 F.3d 

1268, 1274 (Fed. Cir. 2001)). To prove the intent prong of inequitable conduct, “the 

accused infringer must prove by clear and convincing evidence that the material 

information was withheld with the specific intent to deceive the [Patent Office].” Id. 

Waters has cited no independent evidence of specific intent to deceive. Instead, 

it argues that Cohesive’s failure to disclose Guiochon’s belief that the flow generated by 

the claimed invention was not properly characterized as “turbulent” “can have been 

nothing other than intentional.” Reply Br. of Defendant-Cross Appellant Waters Corp. at 

20; see also Br. of Defendant-Cross Appellant Waters Corp. at 75. But the district court 

expressly credited the testimony of the prosecuting attorney and Guiochon that they 

believed the distinction was not material, and concluded that there was no “clear and 

convincing evidence that Cohesive’s omission constituted intentional deceit.” Cohesive, 

526 F. Supp. 2d at 100. Waters has offered no reason for us to disturb these findings. 

We therefore conclude that the district court did not clearly err in its determination 

that Waters had failed to meet its burden of establishing inequitable conduct. See, e.g., 

Star Scientific, 537 F.3d at 1365. 

B. The 25 μm Columns 

We turn next to Cohesive’s appeal of the grant of summary judgment of 

noninfringement by the 25 μm columns. 

2008-1029, -1030, -1031, -1032, -1059 18
Preliminarily, we note that the name “25 μm columns” is somewhat deceiving. 

Apart from the size of the particles that make up the column, the 25 μm columns are 

identical to the infringing 30 μm columns. Cohesive, 526 F. Supp. 2d at 114. In both, 

the particles themselves are irregular in shape, as best shown in figure 3 of the ’874 

patent, reproduced below: 

Because the shape of the particles is not a uniform sphere, the particles in the accused 

25 μm columns do not actually have diameters of 25 μm. Moreover, the parties dispute 

the average size of the particles in the accused 25 μm columns. According to 

Cohesive, the particles in the 25 μm columns have an average diameter of 29.01 μm. 

Id. However, according to Waters, the particles have an average diameter of either 

25.22 or 25.16 μm, depending on the method of calculation. Id. 

1. Claim Construction 

All of the asserted claims of both patents included limitations requiring in effect 

that the column particles have average diameters “greater than about 30 μm.” See, 

e.g., ’874 patent col.20 ll.25-26 (requiring “average diameters of greater than about 

30 μm”); see also supra n.1. Faced with an accused product (the 25 μm columns) that 

2008-1029, -1030, -1031, -1032, -1059 19
was identical to an infringing product (the 30 μm columns) in all respects except for 

particle size, the district court properly focused on the “about 30 μm” limitation of the 

claims. However, the district construed “greater than about 30 μm” expressly with 

reference to the alleged average diameter of the particles in the accused 25 μm 

columns: 

I construe the language ‘‘greater than about 30 microns’’ to exclude 29.01 

microns. 

Cohesive, 526 F. Supp. 2d at 115. 

Although “it is appropriate for a court to consider the accused device when 

determining what aspect of the claim should be construed,” it is not appropriate for the 

court to construe a claim solely to exclude the accused device. Exigent Tech., Inc. v. 

Atrana Solutions, Inc., 442 F.3d 1301, 1310 n.10 (Fed. Cir. 2006). A “claim is construed 

in the light of the claim language . . . not in light of the accused device.” Id. (quoting SRI 

Int’l v. Matsushita Elec. Corp. of Am., 775 F.2d 1107, 1118 (Fed. Cir. 1985) (en banc)) 

(alteration and emphasis in the original). Rather, once the district court identified that 

“greater than about 30 μm” was the language that should be construed, its task was to 

determine the ordinary and customary meaning of that term as understood by a person 

of ordinary skill in the art at the time of the invention, following the guidance of Phillips. 

The district court erred not only by construing the claim merely to exclude the 

accused device, but also by reading the term “about” out of the claim. The district court 

stated that it “d[id] not hesitate in construing ‘about 30 microns’ to exclude a magnitude 

of 29.01 microns,” because the patentee “could have applied for a patent that included 

particles of ‘greater than 29 microns’” if that is what it had intended. Cohesive, 526 F. 

Supp. 2d at 115. But the patentee likewise could have drafted the limitation as “greater 

2008-1029, -1030, -1031, -1032, -1059 20
than 30 μm”—rather than “greater than about 30 μm”—if it had intended the narrow 

scope that the district court gave to the claim. “[C]laims are interpreted with an eye 

toward giving effect to all terms in the claim.” Bicon, Inc. v. Straumann Co., 441 F.3d 

945, 950 (Fed. Cir. 2006). Here, by including the word “about,” the patentee plainly 

intended the limitation “greater than about 30 μm” to encompass columns with particles 

with average diameters that are less than 30 μm, but are still greater than “about” 

30 μm. Cf. Quantum Corp. v. Rodime, PLC, 65 F.3d 1577, 1581 (Fed. Cir. 1995) (“The 

addition of ‘approximately’ which means ‘reasonably close to,’ eliminates the precise 

lower limit of [a] range, and, in so doing extends the scope of the range.” (footnote 

omitted)). 

“[T]he word ‘about’ does not have a universal meaning in patent claims, and [its] 

meaning depends on the technological facts of the particular case.” Pall Corp. v. Micron 

Separations, Inc., 66 F.3d 1211, 1217 (Fed. Cir. 1995). When “about” is used as part of 

a numeric range, “the use of the word ‘about,’ avoids a strict numerical boundary to the 

specified parameter. Its range must be interpreted in its technologic and stylistic 

context.” Id. In determining how far beyond the claimed range the term “about” extends 

the claim, “[w]e must focus . . . on the criticality of the [numerical limitation] to the 

invention.” Ortho-McNeil Pharm., Inc. v. Caraco Pharm. Labs., Ltd., 476 F.3d 1321, 

1327 (Fed. Cir. 2007). In other words, we must look to the purpose that the “about 

30 μm” limitation serves, to determine how much smaller than 30 μm the average 

particle diameter can be and still serve that purpose. To be clear, it is the purpose of 

the limitation in the claimed invention—not the purpose of the invention itself—that is 

2008-1029, -1030, -1031, -1032, -1059 21
relevant. Thus, we ask what function the “about 30 μm” low-end limit on particle size 

plays in the operation of the claimed apparatus and method. 

Here, the reason that the claims place a low-end limit on particle size is clear 

from the specification. The specification of the ’874 patent shows that the function of 

the low-end limit on particle size relates to the ability of the column to capture 

compounds from the liquid at high flow rates. Specifically, the specification teaches that 

“it is believed that the turbulence engendered by . . . high speed flow enhances the 

loading of the solute molecules onto the derivatized surfaces in the pores of the 

particles in the column.” ’874 patent col.17 ll.48-51. The specification describes three 

examples, in which particles of “nominal averaged diameters” of 50 μm, 20 μm, and 10 

μm were evaluated at different flow rates. Id. col.15 ll.18-62. It concludes that the 

desired “turbulence could not be attained” using particles of nominal average diameters 

of 20 μm or 10 μm, but was attained using particles of nominal average diameters of 50 

μm. Id. col.10 ll.1-19; see also id. figs.5-7. 

The specification also teaches that the particles need not be the same size or 

shape. See id. col.8 ll.62-63 (“[The] particles are shaped and selected in a range of 

sizes and shapes . . . .”). In fact, non-spherical and differently shaped particles are 

expressly taught as preferred. See id. col.11 ll.19-28 (teaching that mean or average 

diameter is “not to be construed as limited to particles that are necessarily spherical or 

regular solids” and that “a preferred aspect of the present invention is the irregularity of 

particles’ shape”); id. col.9 ll.2-5 (“In a preferred embodiment, particularly where the 

particles of the column are near the lower end of the acceptable range of cross-section 

dimensions, the particles are irregular . . . .”); id. fig.3 (illustrating irregularly shaped 

2008-1029, -1030, -1031, -1032, -1059 22
particles). Moreover, the specification makes clear that even the average diameter of 

the particles cannot be measured with certainty. See id. col.11 ll.25-26 (describing 

measurement of mean diameters with 95% confidence). Because the particles are not 

spherical, not uniformly shaped, and not precisely measureable, it is not surprising that 

the patent would claim a low-end threshold of “about 30 μm,” rather than precisely 

“30 μm.” Notably, it is the nominal diameter of particles that the specification uses when 

it concludes that the desired level of turbulence cannot be attained when the average 

particle size is too small. See id. col.10 ll.8-19. Thus, the low-end limit on particle size 

performs its function when the nominal average diameter of the particles is above the 

limit (30 μm), even if the actual average diameter varies. 

The specification contains two relevant statements that bear on the range that 

“about” was intended to encompass in the context of the patents in suit. First, the 

specification makes clear that particles with nominal 50 μm diameters attain the desired 

turbulence, while “that turbulence could not be attained with particles” of 20 μm 

diameters. Id. col.10 ll.1-13. Thus, “about 30 μm” cannot include 20 μm. Otherwise, 

the purpose of the “about 30 μm” limitation would not be achieved. 

Second, in describing an analysis of the porosity of columns, the specification 

states: 

To measure porosity, a number of batches of particles were examined, the 

first being a batch (designated herein as CT-50A1-002) of uncoated, 

unfunctionalized highly irregularly shaped, porous alumina particles having 

a nominal diameter of 50μ, but an actual mean diameter, as determined 

by Coulter analysis, of 42.39μ within a 95% confidence factor. 

Id. col.14 ll.22-28 (emphases added). Thus, according to the specification, a batch of 

particles with an actual mean diameter of 42.39 μm may still qualify as having a nominal 

diameter of 50 μm. In other words, the specification treats an average diameter of 

2008-1029, -1030, -1031, -1032, -1059 23
42.39 μm as an average diameter of about 50 μm. This represents an acceptable 

variance of at least 15.22% from the 50 μm nominal diameter. It is therefore reasonable 

to conclude that “about 30 μm” encompasses at least a 15.22% variance from 30 μm. 

Thus, “about 30 μm” should encompass at least 30 μm ± 15.22%, i.e., between 

25.434 μm and 34.566 μm. 

Likewise, the nominal 20 μm particles that do not permit the required level of 

turbulence presumably have actual diameters of 20 μm ± 15.22%, i.e., between 

16.956 μm and 23.044 μm. Thus, our construction of “about 30 μm” should not 

encompass actual diameters of 23.044 μm or less. 

From the intrinsic evidence in the specification, we therefore conclude that “about 

30 μm” should include particles with 25.434 μm diameters and larger, but should 

exclude particles with 23.044 μm diameters and smaller.3

 The specification does not, 

however, provide any concrete guidance as to whether a column with particles with 

measured diameters between 23.044 μm and 25.434 μm meets the “about 30 μm” 

limitation. Absent any such guidance, we neither can nor should draw a hard and fast 

numeric line. Rather, we construe “about 30 μm” to accomplish the function of the lowend limit on particle size described in the specification. From that, we conclude that, for 

particles between 23.044 μm and 25.434 μm, “about 30 μm” means a particle of 

sufficiently large size to assure that a column containing the particles is capable of 

attaining turbulence. This functional approach is necessary and appropriate, because 

 3

 Neither party has pointed to any relevant part of the prosecution history 

that bears on the meaning of “about.” Cohesive points to one useful piece of extrinsic 

evidence—an internal Waters analysis document indicating that Waters considered 

particles as small as 25 μm to be within the range of acceptable measured average 

diameters for a nominally 30 μm product. This evidence is generally consistent with our 

conclusion that “about 30 μm” must encompass 25.434 μm. 

2008-1029, -1030, -1031, -1032, -1059 24
the deliberate imprecision inherent in the word “about” makes it impossible to “capture 

the essence” of the claimed invention in strict numeric terms. Cf. Festo Corp. v. 

Shoketsu Kinzoku Kogyo Kabushiki Co., Ltd., 535 U.S. 722, 731 (2002) (remarking in 

discussion of purpose of doctrine of equivalents that “the nature of language makes it 

impossible to capture the essence of a thing in a patent application”). 

Waters makes two arguments in favor of the district court’s construction, both of 

which we reject. First, Waters argues that the “about 30 μm” limitation applies to the 

average diameter of a single particle, not to the average diameter of all of the particles 

in the column. Thus, according to Waters, an individual, non-spherical particle may 

have an average diameter that is “about”—but less than—30 μm, but the average of all 

of the average diameters of all of the particles in the column must be greater than 

30 μm. We disagree. The specification makes clear that when it refers to an average 

diameter, it is referring to an average diameter of multiple particles in a given 

configuration, not the average diameter of a single particle. Id. col.11 ll.19-28 (“The 

term ‘mean diameter’ as used herein is intended to mean the average (mean) diameter 

or cross-section dimension of the particles regardless of particle configuration and is not 

to be construed as limited to particles that are necessarily spherical or regular solids 

. . . .” (emphases added)). 

Second, Waters claims that “[t]he file history establishes conclusively that the 

inventor intended and understood that his invention required particles with a minimum 

average diameter of 30 μm.” Br. of Defendant-Cross Appellant Waters Corp. at 10. 

Waters points to various statements in the prosecution history that refer to “30 μm 

particles” without the modifier “about.” But Waters ignores that the word “about” 

2008-1029, -1030, -1031, -1032, -1059 25
appears in each of the claims. The claim term “about” cannot be eliminated by the 

prosecution history, unless Cohesive made “a clear and unmistakable disavowal of 

scope during prosecution.” Computer Docking Station Corp., 519 F.3d at 1374. Simply 

using the phrase “30 μm particles” without the qualifier “about” during prosecution is not 

such a clear and unmistakable disavowal. 

Thus, applying the principles articulated in Phillips, 415 F.3d at 1312-19, we 

conclude that the proper construction of “greater than about 30 μm” in claim 1 of the 

’874 patent is: either (1) greater than 25.434 μm, or (2) both greater than 23.044 μm 

and of sufficiently large size to assure that the column is capable of attaining turbulence. 

The same construction is applicable to the terms “not less than about 30 μm” and “in the 

range between about 30 to about 500 μm” in the other asserted claims of both patents. 

2. Literal Infringement 

Based on its erroneous claim construction, the district court concluded that, as a 

matter of law, the 25 μm columns could not infringe, even if they contained particles with 

an average diameter of 29.01 μm, as Cohesive argued. Cohesive, 526 F. Supp. 2d at 

115. Applying the correct construction, if the particles in the 25 μm columns have an 

average diameter of 29.01 μm, they would literally infringe. Summary judgment of 

noninfringement must therefore be reversed. 

However, the district court was correct to deny Cohesive’s motion for summary 

judgment of infringement. Taken in the light most favorable to Waters, the 25 μm 

columns have average diameters of 25.16 μm. Id. at 114. Under the proper claim 

construction, if the average diameter of the 25 μm columns were found to be 25.16 μm, 

they would only infringe if the columns were capable of attaining the desired turbulence. 

Both the actual average diameter of the 25 μm columns and their ability to attain 

2008-1029, -1030, -1031, -1032, -1059 26
turbulence are disputed issues of material fact, making summary judgment on literal 

infringement inappropriate. 

3. Doctrine of Equivalents 

The district court granted summary judgment in favor of Waters, finding no 

infringement under the doctrine of equivalents. Specifically, the district court held that 

“Cohesive has carved out a substantial set of diameters for particle structure, and 

cannot now use the doctrine of equivalents to broaden patent language which 

specifically limits its property rights to a set of particles sized ‘not less than’ a certain 

amount.” Id. at 116. 

We agree that the doctrine of equivalents is not available to Cohesive in this 

case, but for different reasons than those provided by the district court. The district 

court’s analysis was incorrect for several reasons. First, as discussed above, the 

district court incorrectly construed the claim term “about 30 μm” in its analysis of literal 

infringement, and this error also infected its equivalents analysis. Second, the district 

court’s argument, that the breadth of Cohesive’s claim—i.e., that it literally 

encompasses “a substantial set of diameters”—somehow limits its ability to claim 

infringement by equivalents, is wrong as a matter of law. We have never held that the 

doctrine of equivalents is inapplicable to broad claims; to the contrary, we have 

emphasized that pioneering inventions often, by their very nature, result in broader 

application of the doctrine of equivalents. See, e.g., Augustine Med., Inc. v. Gaymar 

Indus., Inc., 181 F.3d 1291, 1301-02 (Fed. Cir. 1999). Finally, the district court’s 

analysis suggests that the doctrine of equivalents cannot be used to broaden a numeric 

range. But as we have repeatedly held, “the fact that a claim recites numeric ranges 

does not, by itself, preclude . . . [reliance] on the doctrine of equivalents.” U.S. Philips 

2008-1029, -1030, -1031, -1032, -1059 27
Corp. v. Iwasaki Elec. Co. Ltd., 505 F.3d 1371, 1378 (Fed. Cir. 2007) (quoting Abbott 

Labs. v. Dey, L.P., 287 F.3d 1097, 1107-08 (Fed. Cir. 2002)) (alterations in the original). 

Nevertheless, we conclude that the doctrine of equivalents is not available to 

Cohesive here, for a different reason. The limitation to which Cohesive seeks to apply 

the doctrine of equivalents is the “about 30 μm” limitation. As we have held, because of 

the way that the patentee has used the word “about” in the context of the written 

description and the claims in this case, construction of the term “about 30 μm” requires 

consideration of the purpose or “criticality” of the limitation to the invention. See OrthoMcNeil, 476 F.3d at 1327. As our construction makes clear, “about 30 μm” 

encompasses particle diameters that perform the same function, in the same way, with 

the same result as the 30 μm particles, as long as those diameters are within the range 

left open by the specific disclosures of the specification. Thus, by electing to include the 

broadening word “about” in the claim, the patentee has in this case already captured 

what would otherwise be equivalents within the literal scope of the claim. Cf. WarnerJenkinson Co., Inc. v. Hilton Davis Chem. Co., 520 U.S. 17, 40 (1997) (“An analysis of 

the role played by each element in the context of the specific patent claim will thus 

inform the inquiry as to whether a substitute element matches the function, way, and 

result of the claimed element, or whether the substitute element plays a role 

substantially different from the claimed element.”) The patentee here has, by its choice 

of claim language, captured the same “range of novelty” that typically justifies 

application of the doctrine of equivalents. See Festo, 535 U.S. at 731 (holding that 

“[t]he scope of a patent is not limited to its literal terms but instead embraces all 

equivalents to the claims described,” because “[t]he language in the patent claims may 

2008-1029, -1030, -1031, -1032, -1059 28
not capture every nuance of the invention or describe with complete precision the range 

of its novelty.”). 

Where, as here, a patentee has brought what would otherwise be equivalents of 

a limitation into the literal scope of the claim, the doctrine of equivalents is unavailable 

to further broaden the scope of the claim. In these circumstances, a patentee cannot 

rely on the doctrine of equivalents to encompass equivalents of equivalents. Here, 

because the “about 30 μm” limitation already literally encompasses diameters that are 

equivalent to 30 μm in the context of the patent, any particle diameter that performs the 

same function, in the same way, with the same result as a 30 μm diameter is already 

within the literal scope of the claim. Cohesive therefore cannot rely on the doctrine of 

equivalents for that limitation. Since the “about 30 μm” limitation was the only disputed 

limitation, the district court was correct to grant summary judgment in favor of Waters on 

the issue of infringement by equivalents. 

C. Damages 

1. Lost Profits 

Following a bench trial, the district court, applying the so-called Panduit test, 

concluded that Cohesive failed to prove that it was entitled to lost profits as a result of 

infringement by Waters’s 30 μm columns. Cohesive, 526 F. Supp. 2d at 118; see

generally Panduit Corp. v. Stahlin Bros. Fibre Works, 575 F.2d 1152 (6th Cir. 1978). 

The district court found both that the 25 μm columns were an “acceptable yet 

noninfringing substitute” for the 30 μm columns and that a separate Waters product—

the Waters 2.1 × 20 mm columns—were “a reasonably acceptable substitute.” Id. at 

119-20. Cohesive appeals, arguing that neither product is an acceptable noninfringing 

substitute. Although “[a]vailability of lost profits is a question of law reviewed without 

2008-1029, -1030, -1031, -1032, -1059 29
deference,” Mars, Inc. v. Coin Acceptors, Inc., 527 F.3d 1359, 1365 (Fed. Cir. 2008), 

“[t]he existence of a noninfringing substitute is a question of fact, reviewable under the 

clearly erroneous standard,” Minn. Min. & Mfg. Co. v. Johnson & Johnson Orth., Inc., 

976 F.2d 1559, 1577 (Fed. Cir. 1992). 

To recover lost profits under the Panduit test, “the patent owner must prove (1) a 

demand for the patented product, (2) an absence of acceptable noninfringing 

substitutes, (3) the manufacturing and marketing capability to exploit the demand, and 

(4) the amount of profit the patent owner would have made.” Standard Havens Prods., 

Inc. v. Gencor Indus., Inc., 953 F.2d 1360, 1373 (Fed. Cir. 1991); see also Panduit, 575 

F.2d at 1156. Standard Havens explains the “acceptable noninfringing substitutes” 

analysis as follows: 

[T]he mere existence of a competing device does not necessarily make 

that device an acceptable substitute. A product on the market which lacks 

the advantages of the patented product can hardly be termed a substitute 

acceptable to the customer who wants those advantages. Accordingly, if 

purchasers are motivated to purchase because of particular features 

available only from the patented product, products without such features—

even if otherwise competing in the marketplace—would not be acceptable 

noninfringing substitutes. 

Thus, to prove that there are no acceptable noninfringing substitutes, the 

patent owner must show either that (1) the purchasers in the marketplace 

generally were willing to buy the patented product for its advantages, or 

(2) the specific purchasers of the infringing product purchased on that 

basis. 

Id. (citations omitted). 

As discussed above, we have concluded that the district court erred in granting 

summary judgment that the 25 μm columns did not infringe the ’874 and ’368 patents. 

Consequentially, the district court erred in concluding that the 25 μm columns were a 

reasonable noninfringing substitute. The availability of the 25 μm columns cannot 

2008-1029, -1030, -1031, -1032, -1059 30
preclude Cohesive from obtaining lost profits, unless and until the district court 

determines that the 25 μm columns are not infringing under the correct claim 

construction. 

It is unclear from the record whether the district court’s findings as to the 2.1 × 

20 mm columns alone would satisfy the Panduit test. The district court made the 

following limited findings as to the 2.1 × 20 mm columns: 

The 2.1 x 20mm, of course, is also a differently-sized column than the 

accused column. Although it is only slightly larger, it would likely not be a 

fully-acceptable substitute for those customers would rather elute their 

compounds over a smaller 1 × 50mm column. Nevertheless, I find it a 

reasonably acceptable substitute. 

Cohesive, 526 F. Supp. 2d at 119. We do not know what the district court means by 

“fully-acceptable substitute” or “reasonably acceptable substitute.” The district court’s 

finding—that the 2.1 × 20 mm columns were not “a fully-acceptable substitute” but were 

nevertheless “a reasonably acceptable substitute”—does not resolve one way or 

another whether they are an acceptable noninfringing substitute under the Standard 

Havens test. 

Thus, we vacate the district court’s determination that Cohesive is not entitled to 

lost profits, and remand for reconsideration based upon its determination of: (1) whether 

the 25 μm columns infringe under the correct claim construction; and (2) whether the 

2.1 x 20 mm columns are acceptable noninfringing substitutes as that term is used in 

Standard Havens. 

2. Willful Infringement 

Applying the standard that we articulated in In re Seagate Technology, LLC, 497 

F.3d 1360, 1371 (Fed. Cir. 2007) (en banc), the district court concluded that Waters’s 

infringement of the ’874 and ’368 patents was not willful. Cohesive, 526 F. Supp. 2d at 

2008-1029, -1030, -1031, -1032, -1059 31
103, 107. “[T]o establish willful infringement, a patentee must show by clear and 

convincing evidence that the infringer acted despite an objectively high likelihood that its 

actions constituted infringement of a valid patent. . . . If this threshold objective 

standard is satisfied, the patentee must also demonstrate that this objectively-defined 

risk (determined by the record developed in the infringement proceeding) was either 

known or so obvious that it should have been known to the accused infringer.” 

Seagate, 497 F.3d at 1371. “The court’s finding [on] willful infringement is one of fact, 

subject to the clearly erroneous standard of review.” Stryker Corp. v. Intermedics 

Orths., Inc., 96 F.3d 1409, 1413 (Fed. Cir. 1996). 

As discussed in detail above, the proper construction of “rigid” was in dispute. 

According to Waters, Cohesive had disavowed all polymeric particles as not “rigid” 

during prosecution based on the Guiochon declaration. While we, like the district court, 

have concluded that the Guiochon declaration did not disavow all polymeric particles, 

see Cohesive, 526 F. Supp. 2d at 106 n.6, we nonetheless agree with the district court 

that Waters could reasonably have read the “rigid” limitation, in light of the specification 

and prosecution history, to require polymeric particles. See id. at 106 & n.6. Because 

“rigid” was susceptible to a reasonable construction under which Waters’s products did 

not infringe, there was not an objectively high likelihood that Waters’s actions 

constituted infringement. See Seagate, 497 F.3d at 1371. The district court’s finding of 

no willful infringement was therefore not clearly erroneous.4

 4

 Because we conclude that the proper claim construction was a sufficiently 

close question to foreclose a finding of willfulness, we need not address Cohesive’s 

arguments concerning the district court’s factual errors in describing the testing that 

Waters performed to assess whether its particles resisted plastic deformation. 

2008-1029, -1030, -1031, -1032, -1059 32
3. Enhanced Damages 

Cohesive argues that the district court erred in declining to award enhanced 

damages, even in the absence of a finding of willfulness. Specifically, relying on the 

analysis in Judge Gajarsa’s concurring opinion in Seagate, Cohesive asks the court to 

overrule Beatrice Foods Co. v. New England Printing & Lithographing Co., in which we 

held that “enhancement of damages must be premised on willful infringement or bad 

faith.” 923 F.2d 1576, 1578 (Fed. Cir. 1991) (quoting Yarway Corp. v. Eur-Control USA, 

Inc., 775 F.2d 268, 277 (Fed. Cir. 1985)); see also Seagate, 497 F.3d at 1377 (Gajarsa, 

J., concurring) (urging that Beatrice Foods be overruled). The majority of the en banc 

court in Seagate did not elect to overrule Beatrice Foods, and we therefore remain 

bound by that decision. See, e.g., Hometown Fin., Inc. v. United States, 409 F.3d 1360, 

1365 (Fed. Cir. 2005) (“[W]e are bound to follow our own precedent as set forth by prior 

panels. . . .”). 

D. Reassignment 

Cohesive requests that this case be assigned to a different district court judge on 

remand, pursuant to 28 U.S.C. § 2106. “The reassignment of a case to a new district 

court judge after remand is a procedural question that is not unique to this court’s 

exclusive jurisdiction. Accordingly, regional circuit law governs reassignment 

questions.” Eolas Techs., Inc. v. Microsoft Corp., 457 F.3d 1279, 1282 (Fed. Cir. 2006). 

The First Circuit uses a three-part inquiry to determine whether reassignment is 

appropriate: 

(1) whether the original judge would reasonably be expected upon remand 

to have substantial difficulty in putting out of his or her mind previouslyexpressed views or findings determined to be erroneous or based on 

evidence that must be rejected, 

2008-1029, -1030, -1031, -1032, -1059 33
(2) whether reassignment is advisable to preserve the appearance of 

justice, and 

(3) whether reassignment would entail waste and duplication out of 

proportion to any gain in preserving the appearance of fairness. 

Maldonado Santiago v. Velazquez Garcia, 821 F.2d 822, 832 (1st Cir. 1987). 

Cohesive makes a single argument in favor of reassignment: that the six year 

delay between the jury’s verdict of infringement and the district court’s judgment on the 

remaining issues shows that the district court judge has a “clear antipathy for this 

matter,” so that reassignment is necessary to preserve the appearance of justice. Br. of 

Plaintiff-Appellant Cohesive Techs., Inc. at 54-55. Waters has not indicated whether it 

favors or opposes reassignment. 

We agree with Cohesive that there was an unreasonable and unacceptable delay 

between the conclusion of the bench trial in August 2002 and the district court’s 

judgment in August 2007. Even more disturbing is the fact that Cohesive moved for a 

preliminary injunction against the 25 μm columns on March 7, 2002, that Cohesive 

converted that motion to a motion for summary judgment at the district court’s 

suggestion, and that the district court still did not rule on the motion for five years, 

despite repeated status inquiries. See 526 F. Supp. 2d at 114. 

Despite our displeasure with the delays in this case, we decline to order 

reassignment. Cohesive makes no argument—and we see no reason—that the district 

court judge would have substantial difficulty putting his previously expressed views or 

findings out of his mind. Moreover, reassignment would necessarily entail a great deal 

of waste and duplication of effort. We have affirmed much of the district court’s 

judgment in this case, and the limited issues on which we have remanded will be most 

easily addressed by the judge who presided over the earlier jury and bench trials and is 

2008-1029, -1030, -1031, -1032, -1059 34
2008-1029, -1030, -1031, -1032, -1059 35

already familiar with the case. On balance, we conclude that no reassignment is 

necessary and expect that the issues remaining on remand will be addressed without 

undue delay. 

III. CONCLUSION 

For the foregoing reasons, we reject the district court’s construction of the term 

“about 30 μm” and construe the term as described above. We reverse the district 

court’s grant of summary judgment of no literal infringement by the 25 μm columns, 

reverse the district court’s grant of judgment as a matter of law on the issue of 

anticipation, vacate the district court’s judgment that Cohesive is not entitled to actual 

damages, and remand. In all other respects, the judgment of the district court is 

affirmed. 

AFFIRMED-IN-PART, REVERSED-IN-PART, VACATED-IN-PART, AND REMANDED

COSTS 

Each party shall bear its own costs. 
UNITED STATES COURT OF APPEALS FOR THE FEDERAL CIRCUIT 

 

2008-1029,-1030,-1031,-1032,-1059 

COHESIVE TECHNOLOGIES, INC., 

 Plaintiff-Appellant, 

v. 

WATERS CORPORATION, 

 Defendant-Cross Appellant. 

Appeal from the United States District Court for the District of Massachusetts in case 

nos. 98-CV-12308, 99-CV-11528, and 01-CV-12307, Judge Douglas P. Woodlock. 

MAYER, Circuit Judge, dissenting. 

I dissent from the majority’s decision to remand the issue of anticipation to the 

district court. See ante at 12-17. The jury having found that U.S. Patent No. 5,772,874 

is not obvious under 35 U.S.C. § 103, remanding the case for “further proceedings” on 

whether the patent is anticipated is a waste of time and resources. 

It is true that the tests for obviousness and anticipation are distinct, and that a 

district court should not refuse to submit a claim of anticipation to the jury merely 

because an accused infringer also asserts an obviousness defense. It does not follow, 

however, that if a jury has already determined that an invention is not obvious, remand 

is required so that it can consider whether the invention is anticipated. The jury here 

considered all of the allegedly anticipating prior art references, but nonetheless returned 

a verdict that the asserted claims are non-obvious. If a series of prior art references did 

not render the claimed invention obvious, how could one of those references contain 
each and every element of the claimed invention so as to render it anticipated? See

Schering Corp. v. Geneva Pharms., Inc., 339 F.3d 1373, 1379 (Fed. Cir. 2003) (a claim 

is anticipated if each and every limitation is found in a single prior art reference). ∗

 

Although a claimed invention can be obvious but not anticipated, it “cannot have 

been anticipated and not have been obvious.” In re Fracalossi, 681 F.2d 792, 

794 (CCPA 1982) (emphasis added). Indeed, this court has repeatedly emphasized 

that “a disclosure that anticipates . . . also renders the claim invalid under § 103, for 

anticipation is the epitome of obviousness.” Connell v. Sears, Roebuck & Co., 722 F.2d 

1542, 1548 (Fed. Cir. 1983) (citations and internal quotation marks omitted); see Johns 

Hopkins Univ. v. Cellpro, Inc., 152 F.3d 1342, 1357 n.21 (Fed. Cir. 1998) (a disclosure 

that anticipates also renders a claim obvious); In re Pearson, 494 F.2d 1399, 1402 

(CCPA 1974) (anticipation is “the ultimate . . . obviousness”) (citations and internal 

quotation marks omitted); In re Kalm, 378 F.2d 959, 962 (CCPA 1967) (“Necessarily, a 

description in a reference which is insufficient as a matter of law to render a composition 

of matter obvious to one of ordinary skill in the art would a fortiori be insufficient to 

‘describe’ the composition as that term is used [for purposes of establishing 

anticipation], a complete description being but the ultimate or epitome of obviousness.”). 

The majority’s assertion that a claim can be anticipated but not obvious, flies in the face 

of a long line of precedent to the contrary. Not surprisingly, it is unable to cite a case 

 ∗

 The majority cites Trintec Indus., Inc. v. Top-U.S.A. Corp., 295 F.3d 1292, 1296 

(Fed. Cir. 2002) for the proposition that “obviousness is not inherent anticipation.” 

Ante at 15. Trintec held that an invention is not inherently anticipated merely because it 

is obvious. That, however, is a wholly separate issue from the issue presented here, 

which is whether claims that are not obvious can ever be anticipated. Trintec does not 

state that non-obvious claims can be inherently anticipated. 

2008-1029,-1030,-1031,-1032,-1059 2
2008-1029,-1030,-1031,-1032,-1059 3

remanding to the district court for consideration of anticipation, while at the same time 

sustaining a determination that claims at issue are not obvious. ∗ ∗

The fallacy of the majority’s approach can be illustrated by a simple example. 

Every apple is a fruit. It follows, therefore, that if something is not a fruit, it cannot be an 

apple. Similarly, since our precedent makes clear that every anticipated claim is 

obvious, it follows that if a claim is not obvious, it cannot be anticipated. 

The present dispute has already dragged on for nearly a decade and I see no 

reason to burden the district court and the parties with additional proceedings. Although 

the majority sends the anticipation issue back to the district court for “further 

proceedings consistent with [its] opinion,” ante at 17, one wonders what it expects the 

court to do. Given the prior non-obviousness determination, it can hardly expect the 

district court to conclude that there is sufficient evidence of anticipation to send the 

issue to a new jury. I would affirm the district court’s directed verdict on anticipation. 

 

** The majority’s reliance on Mendenhall v. Cedarapids, Inc., 5 F.3d 1557, 1563 

(Fed. Cir. 1993), is unsupportable. That case held that a district court did not abuse its 

discretion in refusing to set aside a jury verdict of non-obviousness even though the jury 

also returned a verdict of anticipation by prior public use. The issue here, however, is 

not whether a verdict finding both anticipation by prior public use and non-obviousness 

can be sustained, but whether remand is required to consider anticipation even after the 

jury has determined the claims are not obvious.