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###### Department of Health and Human Services

###### Agency for Toxic Substances and Disease Registry

          - [Docket No. ATSDR-2015-0001]

# AGENCY:

Agency for Toxic Substances and Disease Registry (ATSDR), Department of Health and Human Services (HHS).

# ACTION:

Notice of availability; request for comment.

# SUMMARY:

The Agency for Toxic Substances and Disease Registry (ATSDR), within the Department of Health and Human Services (HHS) announces the availability of Set 29 Draft Toxicological Profiles for review and comment. All toxicological profiles issued as “Drafts for Public Comment” represent ATSDR's best efforts to provide important toxicological information on priority hazardous substances. ATSDR is seeking public comments and additional information or reports on studies about the health effects of Tribufos, Bromodichloromethane, Bromomethane, and 2-Hexanone for review and potential inclusion in the profiles. Although ATSDR considers key studies for these substances during the profile development process, this document solicits any relevant, additional information. ATSDR will evaluate the quality and relevance of such data or studies for possible inclusion into the profile.

ATSDR also seeks comments on the organization and format of the Toxicological Profile for Bromodichloromethane. In an effort to improve the usability of the profiles, ATSDR recently made content and organizational changes based on user feedback, as well as data identifying the most used profile content. Changes include: Removing redundant content; adding summary figures and tables to Chapters 1, 2, 5, and 6 that did not exist in previous Toxicological Profiles; and reformatting the Levels of Significant Exposure (LSE) tables in Chapter 2. ATSDR has only applied the changes to the Draft Toxicological Profile for Bromodichloromethane, but intends to use the new format for future profiles. Specifically, ATSDR would like to know:

(1) Does the chapter organization make it easier for you to find the information you need? For example, are you satisfied with the organization of the health effects chapter by organ system rather than exposure route?

(2) Are the new tables and figures clear and useful? Do they make the Toxicological Profile easier to read?

(3) If you have previously used any Toxicological Profile(s) for your work, which parts or content are the most useful to you, and what do you use it for?

(4) Does the profile contain all of the information you need? If no, please elaborate on what additional information would be helpful.

(5) Is there information you would like to see in the profile that is not currently included? If yes, please elaborate on the additional information you would like to see in the profile.

ATSDR remains committed to providing a public comment period for these documents as a means to provide the best service to the public regarding public health.

# DATES:

Comments must be submitted by October 31, 2018.

# ADDRESSES:

You may submit comments, identified by docket number ATSDR-2015-0001, by either of the following methods:
      -  Internet:                          Access the Federal eRulemaking Portal at                          www.regulations.gov.                          Follow the instructions for submitting comments.                    
      -  Mail:                          Division of Toxicology and Human Health Sciences, Agency for Toxic Substances and Disease Registry, 1600 Clifton Rd. NE, MS F-57, Atlanta, GA, 30329. Attn: Docket No. ATSDR-2015-0001.                    

*Instructions:*                         All submissions must include the agency name and docket number for this notice. All relevant comments will be posted without change. This means that no confidential business information or other confidential information should be submitted in response to this notice. The public comments, responses, and other data submitted in response to the                         **Federal Register**                         notices are available by request from ATSDR. Contact CDC Info at 1-800-232-4636 or                         *cdcinfo@cdc.gov*                         to request this information.                    

# FOR FURTHER INFORMATION CONTACT:

                        Susan Ingber, Agency for Toxic Substances and Disease Registry, Division of Toxicology and Human Health Sciences, 1600 Clifton Rd. NE, MS F-57, Atlanta, GA, 30329, Email:                         *ATSDRToxProfileFRNs@cdc.gov;*                         Phone: 1-800-232-4636.                    

# SUPPLEMENTARY INFORMATION:

                    The Superfund Amendments and Reauthorization Act of 1986 (SARA) [42 U.S.C. 9601*et seq.*] amended the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA or Superfund) [42 U.S.C. 9601*et seq.*] by establishing certain requirements for ATSDR and the U.S. Environmental Protection Agency (EPA) regarding hazardous substances that are most commonly found at facilities on the CERCLA National Priorities List (NPL). Among these statutory requirements is a mandate for the Administrator of ATSDR to prepare toxicological profiles for each substance included on the priority list of hazardous substances [also called the Substance Priority List (SPL)]. This list identifies 275 hazardous substances that ATSDR and EPA have determined pose the most significant potential threat to human health. The SPL is available online at                     *www.atsdr.cdc.gov/​spl.*      ( print page 37813)    

In addition, CERCLA provides ATSDR with the authority to prepare toxicological profiles for substances not found on the SPL. CERCLA authorizes ATSDR to establish and maintain inventory of literature, research, and studies on the health effects of toxic substances (CERCLA Section 104(i)(1)(B)); to respond to requests for health consultations (CERCLA Section 104(i)(4)); and to support the site-specific response actions conducted by the agency.

## Availability

                    The Draft Toxicological Profiles are available online at                     *http://www.atsdr.cdc.gov/​ToxProfiles*                     and at                     *www.regulations.gov,*                     Docket No. ATSDR-2015-0001.                

Pamela I. Protzel Berman,

Director, Office of Policy, Partnerships and Planning, Agency for Toxic Substances and Disease Registry.

[FR Doc. 2018-16557 Filed 8-1-18; 8:45 am]

 BILLING CODE 4163-70-P