37440 Federal Register / Vol. 83, No. 148 / Wednesday, August 1, 2018 / Rules and Regulations 

TABLE 52.385—EPA-APPROVED REGULATIONS—Continued 

Connecticut 

state citation Title/subject 

Dates Federal 

Register 

citation 

Section 

52.370 

Comments/ 

Date adopted description 

by state 

Date approved 

by EPA 

*******

■ 5. Section 52.386 is amended by 

adding paragraph (c) to read as follows: 

§ 52.386 Section 110(a)(2) infrastructure 

requirements. 

* * * * * 

(c) The Connecticut Department of 

Energy and Environmental Protection 

submitted the following infrastructure 

SIPs on these dates: 2006 PM2.5

NAAQS—August 19, 2011 (CAA section 

110(a)(2)(D)(i)(I) transport provisions), 

and 2012 PM2.5 NAAQS—December 14, 

2015. These infrastructure SIPs are 

approved. Also with respect to the 1997 

and 2006 PM2.5, 1997 and 2008 ozone, 

2008 lead, 2010 nitrogen dioxide, and 

2010 sulfur dioxide NAAQS, elements 

related to PSD, which are in CAA 

section 110(a)(2)(C), (D)(i)(II), and (J) 

and were previously conditionally 

approved, are now approved. 

[FR Doc. 2018–16431 Filed 7–31–18; 8:45 am] 

BILLING CODE 6560–50–P 

ENVIRONMENTAL PROTECTION 

AGENCY 

40 CFR Part 180 

[EPA–HQ–OPP–2018–0150; FRL–9980–39] 

Titanium dioxide; Exemption From the 

Requirement of a Tolerance 

AGENCY: Environmental Protection 

Agency (EPA). 

ACTION: Final rule. 

SUMMARY: This regulation amends the 

exemption from the requirement of a 

tolerance for residues of titanium 

dioxide (CAS Reg. No. 13463–67–7) 

when used as an inert ingredient in 

pesticide formulations applied to 

growing crops to allow for use as a 

carrier. SciReg. Inc., on behalf of Bayer 

CropScience Biologics GmbH, submitted 

a petition to EPA under the Federal 

Food, Drug, and Cosmetic Act (FFDCA), 

requesting establishment of an 

exemption from the requirement of a 

tolerance. This regulation eliminates the 

need to establish a maximum 

permissible level for residues of 

titanium dioxide resulting from this use. 

DATES: This regulation is effective 

August 1, 2018. Objections and requests 

for hearings must be received on or 

before October 1, 2018, and must be 

filed in accordance with the instructions 

provided in 40 CFR part 178 (see also 

Unit I.C. of the SUPPLEMENTARY

INFORMATION). 

ADDRESSES: The docket for this action, 

identified by docket identification (ID) 

number EPA–HQ–OPP–2018–0150, is 

available at http://www.regulations.gov 

or at the Office of Pesticide Programs 

Regulatory Public Docket (OPP Docket) 

in the Environmental Protection Agency 

Docket Center (EPA/DC), West William 

Jefferson Clinton Bldg., Rm. 3334, 1301 

Constitution Ave. NW, Washington, DC 

20460–0001. The Public Reading Room 

is open from 8:30 a.m. to 4:30 p.m., 

Monday through Friday, excluding legal 

holidays. The telephone number for the 

Public Reading Room is (202) 566–1744, 

and the telephone number for the OPP 

Docket is (703) 305–5805. Please review 

the visitor instructions and additional 

information about the docket available 

at http://www.epa.gov/dockets. 

FOR FURTHER INFORMATION CONTACT: 

Michael Goodis, Registration Division 

(7505P), Office of Pesticide Programs, 

Environmental Protection Agency, 1200 

Pennsylvania Ave. NW, Washington, DC 

20460–0001; main telephone number: 

(703) 305–7090; email address: 

RDFRNotices@epa.gov. 

SUPPLEMENTARY INFORMATION: 

I. General Information 

A. Does this action apply to me? 

You may be potentially affected by 

this action if you are an agricultural 

producer, food manufacturer, or 

pesticide manufacturer. The following 

list of North American Industrial 

Classification System (NAICS) codes is 

not intended to be exhaustive, but rather 

provides a guide to help readers 

determine whether this document 

applies to them. Potentially affected 

entities may include: 

• Crop production (NAICS code 111). 

• Animal production (NAICS code 

112). 

• Food manufacturing (NAICS code 

311). 

• Pesticide manufacturing (NAICS 

code 32532). 

B. How can I get electronic access to 

other related information? 

You may access a frequently updated 

electronic version of 40 CFR part 180 

through the Government Printing 

Office’s e-CFR site at http://

www.ecfr.gov/cgi-bin/textidx?&c=ecfr&tpl=/ecfrbrowse/Title40/ 

40tab_02.tpl. 

C. How can I file an objection or hearing 

request? 

Under FFDCA section 408(g), 21 

U.S.C. 346a, any person may file an 

objection to any aspect of this regulation 

and may also request a hearing on those 

objections. You must file your objection 

or request a hearing on this regulation 

in accordance with the instructions 

provided in 40 CFR part 178. To ensure 

proper receipt by EPA, you must 

identify docket ID number EPA–HQ– 

OPP–2018–0150 in the subject line on 

the first page of your submission. All 

objections and requests for a hearing 

must be in writing, and must be 

received by the Hearing Clerk on or 

before October 1, 2018. Addresses for 

mail and hand delivery of objections 

and hearing requests are provided in 40 

CFR 178.25(b). 

In addition to filing an objection or 

hearing request with the Hearing Clerk 

as described in 40 CFR part 178, please 

submit a copy of the filing (excluding 

any Confidential Business Information 

(CBI)) for inclusion in the public docket. 

Information not marked confidential 

pursuant to 40 CFR part 2 may be 

disclosed publicly by EPA without prior 

notice. Submit the non-CBI copy of your 

objection or hearing request, identified 

by docket ID number EPA–HQ–OPP– 

2018–0150, by one of the following 

methods: 

• Federal eRulemaking Portal: http:// 

www.regulations.gov. Follow the online 

instructions for submitting comments. 

Do not submit electronically any 

information you consider to be CBI or 

other information whose disclosure is 

restricted by statute. 

• Mail: OPP Docket, Environmental 

Protection Agency Docket Center (EPA/ 

DC), (28221T), 1200 Pennsylvania Ave. 

NW, Washington, DC 20460–0001. 

• Hand Delivery: To make special 

arrangements for hand delivery or 


sradovich on DSK3GMQ082PROD with RULES
Federal Register / Vol. 83, No. 148 / Wednesday, August 1, 2018 / Rules and Regulations 37441 

delivery of boxed information, please 

follow the instructions at http://

www.epa.gov/dockets/contacts.html. 

Additional instructions on 

commenting or visiting the docket, 

along with more information about 

dockets generally, is available at http:// 

www.epa.gov/dockets. 

II. Petition for Exemption 

In the Federal Register of May 18, 

2018 (83 FR 23247) (FRL–9976–87), 

EPA issued a document pursuant to 

FFDCA section 408, 21 U.S.C. 346a, 

announcing the filing of a pesticide 

petition (PP IN–11085) by SciReg. Inc., 

on behalf of Bayer CropScience 

Biologics GmbH, Lukaswiese 4, 23970 

Wismar, Germany. The petition 

requested that the 40 CFR 180.920 

exemption from the requirement of a 

tolerance for residues of titanium 

dioxide (CAS Reg. No. 13463–67–7) be 

amended to allow for use as a carrier 

when used as an inert ingredient in 

pesticide formulations applied to 

growing crops only. That document 

referenced a summary of the petition 

prepared by SciReg. Inc., on behalf of 

Bayer CropScience Biologics GmbH, the 

petitioner, which is available in the 

docket, http://www.regulations.gov. 

There were no comments received in 

response to the notice of filing. 

III. Inert Ingredient Definition 

Inert ingredients are all ingredients 

that are not active ingredients as defined 

in 40 CFR 153.125 and include, but are 

not limited to, the following types of 

ingredients (except when they have a 

pesticidal efficacy of their own): 

Solvents such as alcohols and 

hydrocarbons; surfactants such as 

polyoxyethylene polymers and fatty 

acids; carriers such as clay and 

diatomaceous earth; thickeners such as 

carrageenan and modified cellulose; 

wetting, spreading, and dispersing 

agents; propellants in aerosol 

dispensers; microencapsulating agents; 

and emulsifiers. The term ‘‘inert’’ is not 

intended to imply nontoxicity; the 

ingredient may or may not be 

chemically active. Generally, EPA has 

exempted inert ingredients from the 

requirement of a tolerance based on the 

low toxicity of the individual inert 

ingredients. 

IV. Aggregate Risk Assessment and 

Determination of Safety 

Section 408(c)(2)(A)(i) of FFDCA 

allows EPA to establish an exemption 

from the requirement for a tolerance (the 

legal limit for a pesticide chemical 

residue in or on a food) only if EPA 

determines that the tolerance is ‘‘safe.’’ 

Section 408(b)(2)(A)(ii) of FFDCA 

defines ‘‘safe’’ to mean that ‘‘there is a 

reasonable certainty that no harm will 

result from aggregate exposure to the 

pesticide chemical residue, including 

all anticipated dietary exposures and all 

other exposures for which there is 

reliable information.’’ This includes 

exposure through drinking water and in 

residential settings, but does not include 

occupational exposure. Section 

408(b)(2)(C) of FFDCA requires EPA to 

give special consideration to exposure 

of infants and children to the pesticide 

chemical residue in establishing a 

tolerance and to ‘‘ensure that there is a 

reasonable certainty that no harm will 

result to infants and children from 

aggregate exposure to the pesticide 

chemical residue. . . .’’ 

EPA establishes exemptions from the 

requirement of a tolerance only in those 

cases where it can be clearly 

demonstrated that the risks from 

aggregate exposure to pesticide 

chemical residues under reasonably 

foreseeable circumstances will pose no 

appreciable risks to human health. In 

order to determine the risks from 

aggregate exposure to pesticide inert 

ingredients, the Agency considers the 

toxicity of the inert in conjunction with 

possible exposure to residues of the 

inert ingredient through food, drinking 

water, and through other exposures that 

occur as a result of pesticide use in 

residential settings. If EPA is able to 

determine that a finite tolerance is not 

necessary to ensure that there is a 

reasonable certainty that no harm will 

result from aggregate exposure to the 

inert ingredient, an exemption from the 

requirement of a tolerance may be 

established. 

Consistent with FFDCA section 

408(c)(2)(A), and the factors specified in 

FFDCA section 408(c)(2)(B), EPA has 

reviewed the available scientific data 

and other relevant information in 

support of this action. EPA has 

sufficient data to assess the hazards of 

and to make a determination on 

aggregate exposure for titanium dioxide 

including exposure resulting from the 

exemption established by this action. 

EPA’s assessment of exposures and risks 

associated with titanium dioxide 

follows. 

A. Toxicological Profile 

EPA has evaluated the available 

toxicity data and considered their 

validity, completeness, and reliability as 

well as the relationship of the results of 

the studies to human risk. EPA has also 

considered available information 

concerning the variability of the 

sensitivities of major identifiable 

subgroups of consumers, including 

infants and children. 

The available toxicity studies on 

titanium dioxide via the oral route of 

exposure clearly demonstrate a lack of 

toxicity. The several studies in mice, 

rats, dogs, cats, rabbits and other species 

of varying durations do not indicate 

toxicity, even at very high doses (e.g., 

50,000 ppm or 2,500 mg/kg/day dietary 

exposure for two years in rats). There 

are no studies on the dermal toxicity of 

titanium dioxide and there is no 

expected toxicity via the dermal route of 

exposure because as an insoluble solid 

material, titanium dioxide is not 

absorbed via the skin. 

The available inhalation studies 

indicate that the primary toxicity of 

titanium dioxide is due to deposition of 

the inhaled particles. Although these 

studies suggest equivocal evidence of 

carcinogenicity due to prolonged 

exposure to titanium dioxide particles, 

EPA has determined that these effects 

are not relevant for assessing risk from 

exposure to titanium dioxide when used 

as an inert ingredient in pesticide 

formulations based on the following. 

First, tumors were only observed in two 

of the available studies and only in one 

species. In one study, those tumors were 

only observed in rats continually 

exposed to ultrafine particles of 

titanium dioxide. In the second study, 

tumors were only observed from 

exposure to fine particles of titanium 

dioxide at extremely high 

concentrations (250 mg/m3), in which 

the animals experienced overloading of 

lung clearance, with chronic 

inflammation resulting in lung tumors. 

All but one of the tumors in the second 

study were subsequently reclassified as 

non-neoplastic or non-cancerous in 

nature. No tumors were observed in 

studies involving mice. 

The titanium dioxide used in 

pesticide formulations is considered 

pigmentary grade, not ultrafine or 

nanoscale. Consequently, the tumors 

observed from exposure to ultrafine 

particles of titanium dioxide are not 

relevant for assessing exposure to the 

type of titanium dioxide used in 

pesticide formulations. Following the 

reclassification of the tumors observed 

in the second inhalation study, EPA 

does not consider these effects to be 

strong evidence of carcinogenicity from 

exposure to fineparticle-sized titanium 

dioxide. Further, EPA does not expect 

any reasonably foreseeable uses of 

titanium dioxide in pesticide 

formulations that might result in 

residential exposures that would 

approach the levels of exposure 

necessary to elicit the effects seen in the 

available inhalation study. The levels at 

which effects were observed in that 

study greatly exceed any reasonable 


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37442 Federal Register / Vol. 83, No. 148 / Wednesday, August 1, 2018 / Rules and Regulations 

dose for toxicity testing and any likely 

residential exposure levels. Moreover, 

when used as an inert in pesticide 

formulations, titanium dioxide will be 

bound to other materials, with no 

significant inhalation exposure to 

titanium dioxide particles themselves. 

This position is consistent with the 

National Institute of Occupational 

Health and Safety’s (NIOSH) recent 

assessment that ultrafine but not fine 

titanium dioxide would be considered a 

‘‘potential occupational carcinogen.’’ 

The NIOSH Current Intelligence 

Bulletin ‘‘Occupational Exposure to 

Titanium Dioxide’’ concludes that ‘‘[t]he 

lung tumors observed in rats after 

exposure to 250 mg/m3 of fine TiO2

[titanium dioxide] were the basis for the 

original NIOSH designation of TiO2 as a 

‘‘potential occupational carcinogen.’’ 

However, because this dose is 

considered to be significantly higher 

than currently accepted inhalation 

toxicology practice, NIOSH concluded 

that the response at such a high dose 

should not be used in making its hazard 

identification.’’ NIOSH concluded that 

the data is insufficient to classify fine 

titanium dioxide as a potential 

occupational carcinogen. 

Because the predominant form of 

titanium dioxide used commercially, 

and the form used as an inert ingredient 

in pesticide formulations, is pigment 

grade, which is not in the ultrafine or 

nanoscale particle size range but rather 

in the fine particle size range, EPA 

concludes that carcinogenicity is not a 

concern from exposure to titanium 

dioxide resulting from its use as an inert 

ingredient in pesticide formulations. 

Specific information on the studies 

received and the nature of the adverse 

effects caused by titanium dioxide as 

well as the no-observed-adverse-effect 

level (NOAEL) and the lowest-observedadverse-effect level (LOAEL) from the 

toxicity studies are discussed in the 

final rule published in the Federal 

Register of July 27, 2012 (77 FR 44151) 

(FRL–9354–6) and in the Agency’s risk 

assessment which can be found at 

http://www.regulations.gov in document 

‘‘Titanium Dioxide; Human Health Risk 

Assessment and Ecological Effects 

Assessment to Support Proposed 

Exemption from the Requirement of a 

Tolerance When used as an Inert 

Ingredient in Pesticide Formulations’’ in 

docket ID number EPA–HQ–OPP–2018– 

0150. 

B. Toxicological Points of Departure/ 

Levels of Concern 

Because the available data indicate no 

toxicity via the oral route of exposure, 

no endpoint of concern for that route of 

exposure has been identified in the 

available database. This conclusion is in 

agreement with the conclusion of the 

World Health Organization (WHO) 

Committee on Food Coloring Materials 

that no Acceptable Daily Intake (ADI) 

need be set for the use of titanium 

dioxide based on the range of acute, 

sub-acute, and chronic toxicity assays, 

all showing low mammalian toxicity. 

Similarly, no significant toxicity of 

titanium dioxide is expected via the 

dermal route of exposure, so no 

endpoint was identified. 

Because the effects seen in inhalation 

studies occurred at doses above the 

levels at which pesticide exposure is 

expected and for particle sizes that are 

different from the size of titanium 

dioxide used in pesticide formulations, 

the Agency has concluded that those 

risks are not relevant for assessing risk 

from pesticide exposure and therefore, 

did not identify an endpoint for 

assessing inhalation exposure risk. 

C. Exposure Assessment 

1. Dietary exposure from food and 

feed uses. In evaluating dietary 

exposure to titanium dioxide, EPA 

considered exposure under the 

proposed exemption from the 

requirement of a tolerance and all other 

existing exemptions from the 

requirement of a tolerance for residues 

of titanium dioxide. EPA assessed 

dietary exposures from titanium dioxide 

in food as follows: 

Residues of titanium dioxide are 

exempt from the requirement of a 

tolerance when used as an inert 

ingredient in many different 

circumstances: When used in pesticide 

formulations applied to growing crops 

as a pigment/coloring agent in plastic 

bags used to wrap growing bananas or 

colorant on seeds for planting (40 CFR 

180.920); when used in pesticide 

formulations applied to animals (40 CFR 

180.930); when used as a UV protectant 

in microencapsulated formulations of 

the insecticide lambda-cyhalothrin at no 

more than 3.0% by weight (40 CFR 

180.1195); when used as a UV stabilizer 

in pesticide formulations of 

napropamide at no more than 5% of the 

product formulation (40 CFR 180.1195); 

when used in pesticide placed at 

entrance to bee hives intended to 

control varroa mites in hive at a 

maximum of 0.1% wt/wt (40 CFR 

180.1195); and when used in 

anthraquinone pesticide formulations at 

a maximum of 45% wt/wt (40 CFR 

180.1195). Titanium dioxide is also 

approved for use as a colorant in food 

(21 CFR 73.575). 

Although dietary exposure may be 

expected from use of titanium dioxide 

in pesticide formulations applied to bee 

hives and on other crops (as well as 

from other non-pesticidal sources), a 

quantitative exposure assessment for 

titanium dioxide was not conducted 

because no endpoint of concern was 

identified in the database. 

2. Dietary exposure from drinking 

water. Since a hazard endpoint of 

concern was not identified for the acute 

and chronic dietary assessment, a 

quantitative dietary exposure risk 

assessment for drinking water was not 

conducted, although exposures from 

drinking water may be expected from 

use on food crops. 

3. From non-dietary exposure. The 

term ‘‘residential exposure’’ is used in 

this document to refer to nonoccupational, non-dietary exposure 

(e.g., textiles (clothing and diapers), 

carpets, swimming pools, and hard 

surface disinfection on walls, floors, 

tables). 

Titanium dioxide may be used in nonpesticide products such as paints, 

printing inks, paper and plastic 

products around the home. It has also 

been approved for use in drugs (21 CFR 

73.1575) and in cosmetics (21 CFR 

73.2575 and 73.3126). Additionally, 

titanium dioxide may be used as an 

inert ingredient in pesticides that 

include residential uses; however based 

on the discussion in Unit IV.B., a 

quantitative residential exposure 

assessment for titanium dioxide was not 

conducted. 

4. Cumulative effects from substances 

with a common mechanism of toxicity. 

Section 408(b)(2)(D)(v) of FFDCA 

requires that, when considering whether 

to establish, modify, or revoke a 

tolerance, the Agency consider 

‘‘available information’’ concerning the 

cumulative effects of a particular 

pesticide’s residues and ‘‘other 

substances that have a common 

mechanism of toxicity.’’ 

Because titanium dioxide does not 

have a toxic mode of action or a 

mechanism of toxicity, this provision 

does not apply. 

D. Safety Factor for Infants and 

Children 

Due to titanium dioxide’s low 

potential hazard and the lack of a 

hazard endpoint, it was determined that 

a quantitative risk assessment using 

safety factors applied to a point of 

departure protective of an identified 

hazard endpoint is not appropriate for 

titanium dioxide. For the same reasons 

that a quantitative risk assessment based 

on a safety factor approach is not 

appropriate for titanium dioxide, an 

FQPA SF is not needed to protect the 

safety of infants and children. 


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Federal Register / Vol. 83, No. 148 / Wednesday, August 1, 2018 / Rules and Regulations 37443 

E. Aggregate Risks and Determination of 

Safety 

Taking into consideration all available 

information on titanium dioxide, EPA 

has determined that there is a 

reasonable certainty that no harm to any 

population subgroup will result from 

aggregate exposure to titanium dioxide 

under reasonable foreseeable 

circumstances. Therefore, the 

exemption from tolerance under 40 CFR 

180.920 for residues of titanium 

dioxide, when used as an inert 

ingredient in pesticide formulations is 

safe under FFDCA section 408. 

V. Analytical Enforcement Methodology 

An analytical method is not required 

for enforcement purposes since the 

Agency is establishing an exemption 

from the requirement of a tolerance 

without any numerical limitation. 

VI. Conclusions 

Therefore, EPA is amending the 

exemption from the requirement of a 

tolerance in 40 CFR 180.920 for residues 

of titanium dioxide (CAS Reg. No. 

13463–67–7) when used as an inert 

ingredient (carrier) in pesticide 

formulations. 

VII. Statutory and Executive Order 

Reviews 

This action establishes an exemption 

from the requirement of a tolerance 

under FFDCA section 408(d) in 

response to a petition submitted to the 

Agency. The Office of Management and 

Budget (OMB) has exempted these types 

of actions from review under Executive 

Order 12866, entitled ‘‘Regulatory 

Planning and Review’’ (58 FR 51735, 

October 4, 1993). Because this action 

has been exempted from review under 

Executive Order 12866, this action is 

not subject to Executive Order 13211, 

entitled ‘‘Actions Concerning 

Regulations That Significantly Affect 

Energy Supply, Distribution, or Use’’ (66 

FR 28355, May 22, 2001); Executive 

Order 13045, entitled ‘‘Protection of 

Children from Environmental Health 

Risks and Safety Risks’’ (62 FR 19885, 

April 23, 1997); or Executive Order 

13771, entitled ‘‘Reducing Regulations 

and Controlling Regulatory Costs’’ (82 

FR 9339, February 3, 2017). This action 

does not contain any information 

collections subject to OMB approval 

under the Paperwork Reduction Act 

(PRA) (44 U.S.C. 3501 et seq.), nor does 

it require any special considerations 

under Executive Order 12898, entitled 

‘‘Federal Actions to Address 

Environmental Justice in Minority 

Populations and Low-Income 

Populations’’ (59 FR 7629, February 16, 

1994). 

Since tolerances and exemptions that 

are established on the basis of a petition 

under FFDCA section 408(d), such as 

the exemption in this final rule, do not 

require the issuance of a proposed rule, 

the requirements of the Regulatory 

Flexibility Act (RFA) (5 U.S.C. 601 et 

seq.), do not apply. 

This action directly regulates growers, 

food processors, food handlers, and food 

retailers, not States or tribes, nor does 

this action alter the relationships or 

distribution of power and 

responsibilities established by Congress 

in the preemption provisions of FFDCA 

section 408(n)(4). As such, the Agency 

has determined that this action will not 

have a substantial direct effect on States 

or tribal governments, on the 

relationship between the national 

government and the States or tribal 

governments, or on the distribution of 

power and responsibilities among the 

various levels of government or between 

the Federal Government and Indian 

tribes. Thus, the Agency has determined 

that Executive Order 13132, entitled 

‘‘Federalism’’ (64 FR 43255, August 10, 

1999) and Executive Order 13175, 

entitled ‘‘Consultation and Coordination 

with Indian Tribal Governments’’ (65 FR 

67249, November 9, 2000) do not apply 

to this action. In addition, this action 

does not impose any enforceable duty or 

contain any unfunded mandate as 

described under Title II of the Unfunded 

Mandates Reform Act (UMRA) (2 U.S.C. 

1501 et seq.). 

This action does not involve any 

technical standards that would require 

Agency consideration of voluntary 

consensus standards pursuant to section 

12(d) of the National Technology 

Transfer and Advancement Act 

(NTTAA) (15 U.S.C. 272 note). 

VIII. Congressional Review Act 

Pursuant to the Congressional Review 

Act (5 U.S.C. 801 et seq.), EPA will 

submit a report containing this rule and 

other required information to the U.S. 

Senate, the U.S. House of 

Representatives, and the Comptroller 

General of the United States prior to 

publication of the rule in the Federal 

Register. This action is not a ‘‘major 

rule’’ as defined by 5 U.S.C. 804(2). 

List of Subjects in 40 CFR Part 180 

Environmental protection, 

Administrative practice and procedure, 

Agricultural commodities, Pesticides 

and pests, Reporting and recordkeeping 

requirements. 

Dated: July 11, 2018. 

Michael L. Goodis, 

Director, Registration Division, Office of 

Pesticide Programs. 

Therefore, 40 CFR chapter I is 

amended as follows: 

PART 180—[AMENDED] 

■ 1. The authority citation for part 180 

continues to read as follows: 

Authority: 21 U.S.C. 321(q), 346a and 371. 

■ 2. In § 180.920, revise the inert 

ingredient ‘‘Titanium dioxide (CAS Reg. 

No. 13463–67–7)’’ in the table to read as 

follows: 

§ 180.920 Inert ingredients used preharvest; exemptions from the requirement 

of a tolerance. 

* * * * * 

Inert ingredients Limits Uses 

.......

Titanium dioxide (CAS Reg. No. 13463–67–7) ............. ........................................................................................ Pigment, colorant, carrier. 

.......

[FR Doc. 2018–16470 Filed 7–31–18; 8:45 a.m.] 

BILLING CODE 6560–50–P 


sradovich on DSK3GMQ082PROD with RULES