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                              Immunization Information for You and Your Loved Ones
                              Vaccines by Disease
                              Typhoid Fever


    

    

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Typhoid Fever








  
  
    

  
      



Typhoid fever, often called typhoid, is rare in the United States, but it’s still common in some countries. About 5,700 people get sick with typhoid in the United States every year, usually after traveling to other countries. The typhoid vaccine can help prevent the disease.

There are 2 types of typhoid vaccine:

The**typhoid shot**
	The**oral typhoid vaccine** (swallowed as a pill)Frequently Asked Questions
                        Why is the typhoid vaccine important?
    Typhoid can lead to serious complications, like a high fever that can last for weeks or months. As many as 3 in 10 people who get sick with typhoid and don’t get treatment will die.

Americans can get typhoid while traveling. If you’re traveling to a country where typhoid is common, getting vaccinated is one way to protect yourself.
      What is typhoid?
    Typhoid is caused by bacteria. Symptoms of typhoid may include:

A high fever that lasts a long time
	Weakness
	Stomach pain
	Not feeling hungry
	A rash of flat, pink spots
	Headache
	Diarrhea (watery poop)
	Constipation
	CoughTyphoid spreads when the poop from an infected person gets in water or food. Typhoid can spread when:

Waste from sewers gets into drinking water
	Someone with typhoid doesn’t wash their hands before preparing foodPeople can still have typhoid germs in their body after their symptoms go away, and spread it to others without knowing it. Learn more about typhoid.
      Who needs to get the typhoid vaccine?
    The typhoid vaccine is recommended for people at high risk of coming in contact with typhoid. For example, you may need the typhoid vaccine if you:

Are in close contact with someone who has typhoid
	Work in a lab studying typhoid
	Are traveling to a country where typhoid is commonPeople who get the **typhoid shot**will need 1 dose at least 2 weeks before travel, and a booster every 2 years. People who get the **oral typhoid vaccine** will need 4 doses every other day for a week, with the last dose taken at least 1 week before travel, and a booster every 5 years.

Talk with your doctor about how to protect your family from typhoid. To find out if the typhoid vaccine is recommended where you’re traveling, visit CDC’s travel website.
      Who should not get the typhoid vaccine?
    Some people should not get the typhoid vaccine — or may need to wait to get it.

Typhoid shot

Some people should not get the typhoid shot, including:

Children younger than 2 years
	People who have had an allergic reaction to the typhoid shot or any ingredient in the vaccineIf you’re sick, you may need to wait until you’re feeling better to get the typhoid shot.

Oral typhoid vaccine

Some people should not get the oral typhoid vaccine, including:

Children younger than 6 years
	People who have had an allergic reaction to the oral typhoid vaccine or any ingredient in the vaccineIf you’re sick, you may need to wait until you’re feeling better to get the oral typhoid vaccine. And if you’ve been taking antibiotics, you need to wait for at least 3 days after you’ve stopped taking them to get the vaccine.

Your doctor may recommend that you get the typhoid shot instead of the oral vaccine if you have a weakened immune system, like if you:

Have HIV/AIDS
	Have cancer
	Are taking medicine that can affect the immune systemYour doctor may recommend that you wait to get the typhoid vaccine if you are taking anti-malaria drugs. Your doctor can recommend the vaccine that’s right for you.
      What are the side effects of the typhoid vaccine?
    Side effects from the typhoid vaccine are usually mild and go away in a few days.

Typhoid shot

Side effects of the typhoid shot may include:

Pain, swelling, or redness where the shot was given
	Headache
	FeverSerious side effects from the typhoid shot are very rare.

Oral typhoid vaccine

The most common side effects of the oral typhoid vaccine:

Fever
	HeadacheLess often, the oral typhoid vaccine can cause:

Stomach pain
	Throwing up
	A rashSerious side effects from the oral typhoid vaccine are very rare.

Like any medicine, there's a very small chance that the typhoid vaccine could cause a serious reaction. Keep in mind that getting the typhoid vaccine is much safer than getting typhoid. Learn more about vaccine side effects.
      Where can I get more information about the typhoid vaccine?
    Vaccine Information Statements (VISs) have detailed information about recommended vaccines.

Read the VIS for the typhoid vaccine.
	Find the VIS for the typhoid vaccine in other languages.

                    
  


Get Immunized

Getting immunized is easy. Vaccines and preventive antibodies are available at the doctor’s office or pharmacies — and are usually covered by insurance.

Find out how to get protected.







  Content created by Office of Infectious Disease and HIV/AIDS Policy (OIDP) Content last reviewed April 29, 2021Back to top
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