| 1.  | I      have reviewed this quarterly report on Form 10-Q of The First Bancshares,      Inc.; |
|----------|---------------------------------------------------------------------------------------------|

| 2.  | Based      on my knowledge, this report does not contain any untrue statement      of a material fact or omit to state a material fact necessary      to make the statements made, in light of the circumstances under      which such statements were made, not misleading with respect to      the period covered by this report; |
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| 3.  | Based      on my knowledge, the financial statements, and other financial      information      included in this report, fairly present in all material respects      the financial condition, results of operations and cash flows      of the registrant as of, and for, the periods presented in this      report; |
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| 4.  | The      registrant's other certifying officer and I are responsible for      establishing and maintaining disclosure controls and procedures      (as      defined in Exchange Act Rules 13a-15(e) and 15d-15(e))and internal      control      over financial reporting (as defined in Exchange Act Rules 13a-15(f)      and 15d-15(f)) for the registrant andhave: |
|----------|-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|  | (a)  | Designed      such disclosure controls and procedures, or caused such      disclosure controls and procedures to be designed under our      supervision, to ensure that material information relating      to the registrant, including its consolidated subsidiaries,      is made known to us by others within those entities,      particularly during the period in which this report      is being prepared; |
|--|-----------|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|  | (b) | Designed      such internal control over financial reporting, or caused such      internal      control over financial reporting to be designed under our supervision, to      provide reasonable assurance regarding the reliability of financial      reporting and the preparation of financial statements for external      purposes in accordance with generally accepted accounting      principles; |
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|  | (c)  | Evaluated      the effectiveness of the registrant's disclosure controls      and procedures and presented in this report our conclusions      about the effectiveness of the disclosure controls      and procedures, as of the end of the period covered by      this report based on such evaluation;and |
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|  | (d)  | Disclosed      in this report any change in the registrant's internal      control over financial reporting that occurred during      the registrant's most recent fiscal quarter (the registrant's      fourth fiscal quarter in the case of an annual report)      that has materially affected, or is reasonably likely      to materially affect, the registrant's internal control      over financial reporting; and |
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| 5.  | The      registrant's other certifying officer and I have disclosed, based      on our most recent evaluation of internal control over inancial      reporting, to the registrant's auditors and the audit committee      of the registrant's board of directors (or persons performing      the equivalent functions): |
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|  | (a)  | All      significant deficiencies and material weaknesses in the design      or operation of internal control over financial reporting      which are reasonably likely to adversely affect the registrant's      ability to record, process, summarize and report financial      information; and |
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|  | (b)  | Any      fraud, whether or not material, that involves management or      other employees who have a significant role in the registrant's      internal control over financialreporting. |
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|                              |   |                                       |   |
|-----------------------------------|--------|--------------------------------------------|--------|
| Date:      November      12, 2010 |   | /s/      DeeDee Lowery                     |   |
|                              |   | DeeDee      Lowery, Executive Vice         |   |
|                              |   | President      and Chief Financial Officer |   |
|                              |   |                                       |   |

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