1

Appendix D. Citations Considered to be Part of the Data Base Supporting the 

Reregistration Eligibility Decision of MGK-264 

MRID Citation Reference 

40195801 Meinen, V. (1986) Product Chemistry Data Requirements for MGK 264, Insecticide Synergist. 

Unpublished study prepared by McLaughlin Gormley King Co. 77 p. 

40352300 McLaughlin Gormley King Co. (1987) Submission of Data in Response to Data Call-in Notice for 

Chronic Toxicology. Transmittal of 1 study. 

40352301 Schardein, J. (1987) Teratological Study of MGK 264 Insecticide Synergist Administered Orally to 

Albino Rabbits: Rept. No. 551- 015. Unpublished study prepared by International Research and 

Development Corp. 86 p. 

40359701 Trahanovsky, W. (1987) Identification and Discussion of the Forma- tion of Impurities in MGK 

264, Insecticide Synergist. Unpub- lished study prepared by Iowa State Univ. 124 p. 

40374900 McLaughlin Gormley King Co. (1987) Toxicity submission for Pyrocide Intermediate 7130. 

Transmittal of 1 study. 

40399100 McLaughlin Gormley King Co. (1987) Submission of Mutagenicity Data to Support the 

Registration for MGK 264, Insecticide Synergist. Transmittal of 4 studies. 

40399101 Lawlor, T. (1986) Salmonella/Mammalian-microsome Plate Incorpora- tion Mutagenicity Assay 

(Ames Test): MGK 264, Insecticide Syner- gist: Study No. T5205.501014. Unpublished study 

prepared by Microbiological Associates, Inc. 68 p. 

40399102 Putman, D. (1987) Chromosome Aberrations in Chinese Hamster Ovary (CHO) Cells with a 

Confirmatory Assay: MGK 264 Insecticide Syn- ergist: Study No. T5205.337001. Unpublished 

study prepared by Microbiological Associates, Inc. 28 p. 

40399103 Curren, R. (1987) Unscheduled DNA Synthesis in Rat Primary Hepato- cytes: MGK 264, 

Insecticide Synergist: Study No. T5205.380009. Unpublished study prepared by Microbiological 

Associates, Inc. 29 p. 

40438304 Busch, B. (1987) Primary Eye Irritation Study of ... ?Raid Fogger 15| in New Zealand White 

Rabbits: Study No. 9405A. Unpublished study prepared by Food & Drug Research Laboratories, 

Inc. 32 p. 

40438305 Busch, B. (1987) Primary Dermal Irritation Study of ... ?Raid Fogg- er 15| in New Zealand White 

Rabbits: Study No. 1-9405A. Unpub- lished study prepared by Food & Drug Research 

Laboratories, Inc. 29 p. 

40443700 McLaughlin Gormley King Co. (1987) Submission of Data To Support the Registration of MGK 

264: Product Chemistry Data. Transmitt- al of 1 study. 

40443701 Meinen, V. (1987) Product Identity and Disclosure of Ingredients. Unpublished study prepared 

McLaughlin Gormley King Co. 3 p. 

40528900 McLaughlin Gormley King Co. (1988) Submission of Chemistry Data in Support of MGK 264 

Insecticide Synergist. Transmittal of 1 study. 

40528901 Kassera, D. (1988) Physical and Chemical Properties Test Require- ments for Product Chemistry of 

MGK 264, Insecticide Synergist. Unpublished study prepared by McLaughlin Gormley King Co. 

23 p. 

41519106 Robbins, G. (1990) Guinea Pig Sensitization (Buehler): Lab Project Number: F2072. Unpublished 

study prepared by Cosmopolitan Safe ty Evaluation, Inc. 16 p. 

41526102 Blakemore, G.; Burgess, D. (1990) Acute Flow-Through Toxicity of MGK-264 to Daphnia magna: 

Final Report # 38497. Unpublished study prepared by Analytical Bio-Chemistry Laboratories, Inc. 

134 p. 

41528400 Fermenta Animal Health Co. (1990) Submission of Product Chemistry Data in Support of 

Registration of Ectogard Pet Spray with Tenocide Insect Growth Regulator. Transmittal of 1 study. 

41660301 Schardein, J. (1989) Range-Finding Developmental Toxicity Study in Rats: MGK 264: Lab Project 

Number: 551-025. Unpublished study prepared by International Research and Development Corp. 

35 p. 

41660302 Schardein, J. (1990) Developemental Toxicity Study in Rats: MGK 264 Insecticide Synergist: Lab 

Project Number: 551-026. Unpublished study prepared by International Research and Development 

Corp. 97 p. 
2

MRID Citation Reference 

41668800 CSA Limited, Inc. (1990) Submission of Product Chemistry Data to Support the Registration of the 

Chem Spray Roach and Ant Spray. Transmittal of 1 Study. 

41687301 Long, R.; Foster, J.; Hoxter, K.; et al. (1990) MGK 264: A Dietary LC50 Study with the Northern 

Bobwhite: Lab Project Number: 163- 110. Unpublished study prepared by Wildlife International 

Ltd. 35 p. 

41687302 Long, R.; Foster, J.; Hoxter, K. et al. (1990) MGK 264: A Dietary LC50 Study with the Mallard: 

Lab Project Number: 163/111. Unpub- lished study prepared by Wildlife International Ltd. 35 p. 

41692700 Unicorn Laboratories (1990) Submission of Product Chemistry Data in Support of Unicorn House 

& Carpet Spray #6 Application for Regi- stration. Transmittal of 1 study. 

41692701 McLaughlin Gormley King Co. (1990) Unicorn House & Carpet Spray #6: End Use Product 

Chemistry: Lab Project Number: 90-107. 8 p. 

41703200 McLaughlin Gormley King Co. (1990) Submission of Mutagenicity Data in support of MGK 264 

Insecticide Synergist Data Call-in. Transmittal of 1 study. 

41703201 Curren, R. (1990) Unscheduled DNA Synthesis in Rat Primary Hepato- cytes: MGK 264 

Insecticide Synergist: Final Report: Lab Project Number: T5205.380026. Unpublished study 

prepared by Microbiolo- gical Associates, Inc. 25 p. 

41716900 Roussel Bio Corp. (1990) Submission of Data To Support New Product Registration of Tralex 

Aerosol: Product Chemistry, Efficacy and Toxicology Studies. Transmittal of 10 studies. 

41752304 Hazelton Raltech, Inc. (1991) Raid Fogger Formula V: Primary Eye Irritation (Instilled in Eye): 

Lab Project Number: 5198D132-T1. Unpublished study. 18 p. 

41752305 Hazleton Raltech, Inc. (1991) Raid Fogger Formula V: Acute Oral (Toxicity in Rats): Lab Project 

Number: 5198D132-T2. Unpub- lished study. 11 p. 

41752306 Hazleton Raltech, Inc. (1991) Raid Fogger Formula V: Primary Dermal Irritation: Lab Project 

Number: 5198D132-T3. Unpublished study. 9 p. 

41810307 Carlson, D. (1991) Storage Stability Data: Evercide Concentrate 2560. Unpublished study prepared 

by McLaughlin Gormley King Co. 8 p. 

41819700 MGK (1991) Submission of Toxicology Data to Support the Application for Registration of MGK 

264, Insecticide. Transmittal of 1 Study. 

41819701 Bowman, J.; Stuerman, L. (1991) Acute Flow-Through Toxicity of MGK 264 to Bluegill: Lab 

Project Number: 38495. Unpublished study prepared by Analytical Bio-Chemistry Laboratories, 

Inc. 146 p. 

41860600 MGK Co. (1991) Submission of toxicity data to support the registra- tion standard for MGK 264, 

Insecticide Synergist. Transmittal of 2 studies. 

41860601 Gabriel, D. (1991) MGK 264, Insecticide Synergist/Code #151-91: Acute Dermal Toxicity Single 

Level--Rabbits: Lab Project Number: 91-7238A. Unpublished study prepared by Biosearch, Inc. 12 

p. 

41860602 Bielucke, J. (1991) MGL 264, Insecticide Synergist/Code 151-91: Primary Eye Irritation--Rabbits: 

Lab Project Number: 91-7238A. Unpublished study prepared by Biosearch, Inc. 13 p. 

41911500 MGK (1991) Submission of Data to Support the Reregistration of MGK 264: Toxicology Data. 

Transmittal of 1 study. 

41911501 Bowman, J. (1991) Acute Flow-Through Toxicity of MGK 264 to Rainbow Trout (Oncorhynchus 

mykiss): Lab Project Number: 38496. Unpublished study prepared by Analytical Bio-Chemistry 

Laboratories, Inc. 144 p. 

42008501 Postorino, N. (1991) Technical Service Ectoparasiticide Report ?on Human Adverse Reaction to| 

Adams Flea and Tick Mist Formulation: Lab Project Number: 096. Unpublished study prepared by 

Smith- Kline Beecham, Animal Health. 2 p. 

42008600 MGK Co. (1991) Submission of residue data in support of reregistration of MGK 264. Transmittal 

of 5 studies. 

42008601 Meinen, V.; Bergman, J. (1991) Residue Study of Pyrethrins, Piperonyl Butoxide, and MGK 264 in 

Certain Food Commodities Resulting From Use as a Space Spray in a Simulated Feed and Food 

Processing Situation: Lab Study Number: GLP-078. Unpublished study prepared by MGK Co. 145 

p. 

42082900 MGK Co. (1991) Submission of product chemistry data to support the reregistration of N-Octyl 

bicycloheptane dicarboximide. Transmittal of 1 study. 
3

MRID Citation Reference 

42082901 Meinen, V. (1991) Physical and Chemical Characteristics of MGK 264 Insecticide Synergist 

(Supplemental Information Regarding EPA Response to Phase 3 Submission). Unpublished study 

prepared by by MGK Co. 40 p. 

42093802 Blair, M. (1991) Eighteen Month Dietary Oncogenicity Study in Mice with MGK 264 Insecticide 

Synergist: Lab Project Number: 551-011. Unpublished study prepared by International Research 

and Development Corp. 1459 p. 

42093803 Butler, W. (1991) Review of Selected Tissues from IRDC Study 551- 011: an 18 Month Study on 

MGK 264 in the CD-1 Mouse. (Supplement to MRID 42093802): Lab Project Number: 551-011. 

Unpublished study prepared by BIBRA Toxicology International. 13 p. 

42148100 McLaughlin Gormley King Co. (1991) Submission of Data To Support Registration of MGK 264 

(n-Octyl bicycloheptene dicarboximide) Insecticide Synergist: Toxicology Studies. Transmittal of 

2 studies. 

42148101 Blair, M. (1989) Two Month Dietary Range-Finding Toxicity Study in Dogs with MGK 264: Lab 

Project Number: 551-029. Unpublished study prepared by International Research and Development 

Corp. 211 p. 

42148102 Balir, M. (1991) One Year Dietary Toxicity Study in Dogs with MGK-264: Lab Project Number: 

551-031. Unpublished study prepared by International Research and Development Corp. 852 p. 

42155700 McLaughlin Gormley King Co. (1991) Submission of Data To Support Registration of MGK 264, 

Insecticide Synergist: Toxicology Study. Transmittal of 1 study. 

42155701 Schardein, J. (1991) Two-Generation Reproduction Study of MGK 264 in the Albino Rat: Lab 

Project Number: 551-027. Unpub- lished study prepared by International Research and Development Corp. 861 p. 

42162600 MGK Co. (1991) Submission of toxicity data in support of registrat- ion of Evercide Intermediate 

2494. Transmittal of 1 study. 

42222600 McLaughlin Gormley King Co. (1992) Submission of Data To Support MGK 264, Insecticide 

Synergist Registration: Environmental Fate Studies. Transmittal of 2 studies. 

42222601 Abney, B.; Gorman, M. (1992) Hydrolysis of MGK 264 as a Function of pH at 25(degree)C, 

Definitive Investigations: Final Report: Lab Project Number: 39551. Unpublished study prepared 

by ABC Labs, Inc. 43 p. 

42222602 Pratt, M.; Gorman, M. (1992) Determination of the Aqueous Photolysis Rate of MGK 264: Final 

Report: Lab Project Number: 39547. Unpublished study prepared by ABC Labs, Inc. 45 p. 

42228400 Daniel M. Riccio (1992) Submission of animal exposure data for Hartz 2 in 1 Flea and Tick Dip 

(permethrins and MGK 264) in response to FIFRA 6(a)(2) requirements for incident reports. 

Transmittal of 1 study. 

42355000 MGK (1992) Submission of Environmental Data in Support of Reregistration for MGK 264, 

Insecticide Synergist. Transmittal of 2 studies. 

42355001 Abney, B.; Gorman, M. (1992) Hydrolysis of MGK 264 as a Function of pH at 25 (degree)C, 

Definitive Investigations: Final Report: Lab Project Number: 39551. Unpublished study prepared 

by ABC Laboratories, Inc. 43 p. 

42355002 Pratt, M. ; Gorman, M. (1992) Determination of the Aqueous Photolysis Rate of MGK 264: Final 

Report: Lab Project Number: 39547. Unpublished study prepared by ABC Laboratories, Inc. 45 p. 

42360500 Farnam Companies, Inc. (1992) Submission of product chemistry data in support of the registration 

of Farnam Super Swat. Transmittal of 1 study. 

42622501 Gorman, M. (1992) Soil/Sediment Adsorption-Desorption of MGK 264: Final Report: Lab Project 

Number: 39546. Unpublished study prepared by ABC Labs, Inc. 56 p. 

42622502 Flynn, J.; Gorman, M. (1992) Addendum to Soil/Sediment Adsorption-Desorption of MGK 264: 

Lab Project Number: 39546A. Unpublished study prepared by ABC Labs, Inc. 37 p. 

42627200 MGK (1993) Submission of toxicity data in support of the registration of Pyrocide Fogging 

Concentrate 5628. Transmittal of 6 studies. 

42729700 MGK (1993) Submission of metabolism data in support of the MGK 264 (N-Octyl bicycloheptene 

dicarboximide) registration. Transmittal of 6 studies. 

42729701 Selim, S. (1991) Determination of Expired (14 Co2) Following Oral Dosing of (Hexyl-1-(carbon 

14)) MGK 264 in the Rat: Lab Project Number: P01931: A490-1104. Unpublished study prepared 
4

MRID Citation Reference 

by Biological Test Center. 51 p. 

42729702 Selim, S. (1992) Absorption, Distribution, Metabolism and Excretion Studies of (Hexyl-1-(carbon 

14)) MGK 264 in the Rat: Lab Project Number: P01932: 91-0431.btc. Unpublished study prepared 

by Biological Test Center. 175 p. 

42729703 Selim, S. (1993) Absorption, Distribution, Metabolism and Excretion Studies of (Hexyl-1-(carbon 

14)) MGK 264 in the Rat: An Addendum: Lab Project Number: P01932: 92-0409.btc. Unpublished 

study prepared by Biological Test Center. 141 p. 

42729704 Selim, S. (1991) Determination of Expired (14 Co2) Following Oral Dosing of (Norbornene-2,3-

(carbon 14)) MGK 264 in the Rat: Lab Project Number: P01930: A491-0407. Unpublished study 

prepared by Biological Test Center. 48 p. 

42729705 Selim, S. (1991) Absorption, Distribution, Metabolism and Excretion Studies of (Norbornene-2,3-

(carbon 14)) MGK 264 in the Rat: Lab Project Number: P01933: A491-0617. Unpublished study 

prepared by Biological Test Center. 172 p. 

42729706 Selim, S. (1993) Absorption, Distribution, Metabolism and Excretion Studies of (Norbornene-2,3-

(carbon 14)) MGK 264 in the Rat: An Addendum: Lab Project Number: P01933: 92-0316.btc. 

Unpublished study prepared by Biological Test Center. 178 p. 

42807500 MGK Co. (1993) Submission of environmental fate data in support of registration for MGK 264, 

Insecticide Synergist. Transmittal of 1 study. 

42807501 Gorman, M. (1993) Determination of the Photolysis Rate of MGK 264 on the Surface of Soil: Final 

Report: Lab Project Number: 39549. Unpublished study prepared by ABC Laboratories, Inc. 51 p. 

42970600 McLaughlin Gormley King Co. (1993) Submission of Toxicity Data for MGK 264 Insecticide 

Synergist in Support of Reregistration. Transmittal of 1 Study. 

42970601 Blair, M. (1989) 13 Week Dietary Range-Finding Toxicity Study in Rats with MGK 264: Lab 

Project Number: 551-028. Unpublished study prepared by International Research and Development 

Corp. 240 p. 

42972400 McLaughlin Gormley King Co. (1993) Submission of Storage Stability Data in Support of New 

Registration for ETOC Concentrate 2634. Transmittal of 1 study. 

42972401 Carlson, D. (1993) Storage Stability Data: Etoc Concentrate 2634: Lab Project Number: GLP-466: 

466PRE: 466. Unpublished study prepared by McLaughlin Gormley King Co. 8 p. 

42974600 McLaughlin Gormley King Co. (1993) Submission of Metabolism Data in Support of 

Reregistration of MGK 326 (Di-n-propyl Isocinchomeronate. Transmittal of 3 studies. 

42974602 Selim, S. (1990) Absorption and Mass Balance of Formulated (carbon 14)-MGK 326 after Topical 

Administration to Healthy Volunteers: Lab Project Number: PO2035: PBR-900426-2: 92-0208. 

BTC. Unpublished study prepared by Biological Test Center. 189 p. 

42976700 McLaughlin Gormley King Co. (1993) Submission of Metabolism Data in Support of 

Reregistration of MGK-264. Transmittal of 2 Studies. 

42976701 Selim, S. (1992) Absorption and Mass Balance of (carbon 14)- MGK 264 After Topical 

Administration to Healthy Volunteers: Lab Project Number: PBR-910204-2: 902057: 92-

0403.BTC. Unpublished study prepared by Biological Test Center. 175 p. 

42976702 Selim, S. (1992) Absorption and Mass Balance of Formulated (carbon 14)-MGK 264 After Topical 

Administration to Healthy Volunteers: Lab Project Number: PBR-910205-3: P02058: 92-

0404.BTC. Unpublished study prepared by Biological Test Center. 186 p. 

43005300 McLaughlin Gormley King Co. (1993) Submission of Toxicology Data in Support of 

Reregistration of MGK-264 Insecticide Synergist. Transmittal of 1 Study. 

43005301 Goldenthal, E. (1993) 24 Month Dietary Chronic Toxicity and Oncogenicity Study in the Rat with 

MGK-264: Lab Project Number: 551-030. Unpublished study prepared by International Research 

and Development Corp. 2227 p. 

43012400 Whitmire Inc. (1993) Submission of product chemistry and toxicity data in support of registration 

for Whitmire TC 96. Transmittal of 7 studies. 

43012401 Sarli, M. (1993) Whitmire TC 96: Product Chemistry: Lab Project Number: WRL/93/0082: 

WRL/93/0083: WRL/93/0082/93/0083. Unpublished study prepared by Whitmire Research 

Laboratories, Inc. 10 p. 
5

MRID Citation Reference 

43194501 Flynn, J. (1994) Aerobic Soil Metabolism of MGK 264, Definitive Investigations: Final Report: 

Lab Project Number: 39611. Unpublished study prepared by ABC Lab., Inc. 68 p. 

43194502 Flynn, J. (1994) Anaerobic Soil Metabolism of MGK 264, Definitive Investigations: Final Report: 

Lab Project Number: 39610. Unpublished study prepared by ABC Lab., Inc. 68 p. 

43199200 Whitmire Research Laboratories, Inc. (1994) Submittal of Product Chemistry, Acute Toxicity, and 

Target Animal Safety Data in Support of Registration of Whitmire Flea Foam with Fenoxycarb, 

V.6. Transmittal of 10 studies. 

43309000 McLaughlin Gormley King Co. (1994) Submission of Toxicity Data in Support of Reregistration of 

Octyl Bicycloheptene Dicarboximide. Transmittal of 1 Study. 

43309001 Newton, P. (1994) A Subchronic (3-Month) Inhalation Toxicity Study of MGK 264 Insecticide 

Synergist in the Rat via Whole Body Exposure: Final Report: Lab Project Number: 91-8364. 

Unpublished study prepared by Pharmaco LSR, Inc. 1216 p. 

43313700 Claire Manufacturing Co. (1994) Submission of product chemistry data in support of the 

registration for Claire Fast Kill Residual Roach & Ant Killer. Transmittal of 1 study. 

45254201 Leng, J. (1986) Range-Finding Teratology Study in Rabbits with MGK 264 Insecticide Synergist: 

Lab Project Number: TX025-87. Unpublished study prepared by International Research and 

Development Corporation. 33 p. 

45277700 Speer Product Inc. (2000) Submission of Product Chemistry Data in Support of the Application for 

Registration of Speer DEET Towelette. Transmittal of 1 Study. 

46261101 Moore, G. (2001) Dermal Sensitization Study in Guinea Pigs (Buehler Method): Multicide Lice 

and Dust Mite Spray 27911 (Non-Volatiles). Project Number: 10291, P328. Unpublished study 

prepared by Product Safety Labs, Food Products Laboratory and New Jersey Laboratories. 26 p. 

92122004 Rogosheske, S. (1990) Mc Laughlin Gormley King Co. Phase 3 Summary of MRID 00150979. 

Acute Inhalation of MGK 264 Insecticide Synergist in the Rat. Prepared by Biosearch Inc. 10 p. 

92122005 Rogosheske, S. (1990) Mc Laughlin Gormley King Co. Phase 3 Summary of MRID 00150978. 

Primary Dermal Irritation Study on MGK 264 Insecticide Synergist: Project No. 81-2837A. 

Prepared by Biosearch Inc. 9 p. 

92122006 Rogosheske, S. (1990) Mc Laughlin Gormley King Co. Phase 3 Summary of MRID 40352301. 

Teratological Study of MGK 264 Insecticide Synergist on Albino Rabbits. Prepared by 

International Research & Development Corp. 10 p. 

92122007 Rogosheske, S. (1990) Mc Laughlin Gormley King Co. Phase 3 Summary of MRID 40399101 and 

Related MRIDs 40399102, 40399103, 40399104. Mutagenicity Studies on MGK 264 Insecticide 

Synergist. Prepared by Microbiological Associates, Inc. 24 p. 

92122008 Rogosheske, S. (1990) Mc Laughlin Gormley King Co. Phase 3 Summary of MRID 00150978. 

Dermal Sensitization of MGK 264 Insecticide Synergist in the Guinea Pig: Project No. 81-2837A. 

Prepared by Biosearch Inc. 12 p. 

92122999 Mc Laughlin Gormley King Co. (1990) Reregistration Phase 3 Response: Octyl bicycloheptene 

dicarboximide. Correspondence and Supporting Material.