UNITED STATES ENVIRONMENTAL PROTECTION AGENCY

WASHINGTON, D.C. 20460

 OFFICE OF

 CHEMICAL SAFETY AND 

POLLUTION PREVENTION

July 11, 2014

Charles Levey

Team Lead

Insecticides/Fungicides

Syngenta

410 S Swing Rd

Greensboro, NC 27419

Dear Mr. Levey:

Subject: Agency initiated action to update rates and required labeling from the Profenofos 

IRED August 2000

EPA Reg. No. 100-669

Submissions dated September 3, 2009

The proposed labeling referred to above, submitted in connection with registration under 

the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), is acceptable provided that you 

submit two copies of your final printed label before you release the product for shipment. 

Products shipped after 18 months from the date of this amendment or the next printing of the 

label whichever occurs first, must bear the new revised label. Your release for shipment of the 

product bearing the amended label constitutes acceptance of these conditions. If these conditions

are not complied with, the registration will be subject to cancellation in accordance with FIFRA 

sec. 6(e). 

A stamped copy is enclosed for your records. If you have any questions, please contact 

Marianne Lewis at (703) 308-8043 or lewis.marianne@epa.gov.

Sincerely,

Venus Eagle, Product Manager 01

Insecticide-Rodenticide Branch

Registration Division

Office of Pesticide Programs
(Booklet)

RESTRICTED USE PESTICIDE 

FOR RETAIL SALE TO AND USE ONLY BY 

CERTIFIED APPLICATORS OR PERSONS 

UNDER THEIR DIRECT SUPERVISION, AND ONLY 

FOR THOSE USES COVERED BY THE 

CERTIFIED APPLICATOR’S CERTIFICATION 

DUE TO HIGH TOXICITY. 

Curacron® 8E Insecticide-Miticide 

Group 1B Insecticide

For insect and mite control in cotton 

Closed System Loading and Mixing and Enclosed Tractor Cab Required 

Active Ingredient: 

Profenofos1

 ................................................................................................ 73.0%* 

Other Ingredients**: 27.0% 

Total: 100.0% 

1

CAS No. 41198-08-7 

*1 gallon contains 8 lb of profenofos. 

**Contains petroleum distillates 

KEEP OUT OF REACH OF CHILDREN. 

CAUTION

Si usted no entiende etiqueta busque a alguien para que se la explique a usted en 

detalle. (If you do not understand the label find someone to explain it to you in detail.) 

See additional precautionary statements and directions for use in booklet. 

EPA Reg. No. 100-669 

EPA Est. XXXXX 

Formulated in the USA 

SCP 669 MAS 0509 

10 Gallons 

Net Contents

07/11/2014

100-669
-2-

PRECAUTIONARY STATEMENTS 

HAZARDS TO HUMANS AND DOMESTIC ANIMALS 

CAUTION

Harmful if swallowed. Harmful if absorbed through skin. Causes moderate eye 

irritation. Avoid contact with skin, eyes, or clothing. Prolonged or frequently repeated 

skin contact may cause allergic reactions in some individuals. 

FIRST AID 

This product contains an organophosphate that inhibits cholinesterase

If swallowed y Immediately call a poison control center or doctor 

y Do not induce vomiting unless told to by a poison control center 

or doctor.

y Do not give any liquid to the person. 

y Do not give anything by mouth to an unconscious person. 

If on skin or 

clothing

y Take off contaminated clothing 

y Rinse skin immediately with plenty of water for 15 – 20 minutes. 

y Call a poison control center or doctor for treatment advice.

If in eyes y Hold eye open and rinse slowly and gently with water for 15-20 

minutes.

y Remove contact lenses, if present, after the first 5 minutes, then 

continue rinsing eye. 

y Call a poison control center or doctor for treatment advice. 

If Inhaled y Move person to fresh air. 

y If person is not breathing, call 911 or ambulance, then give 

artificial respiration, preferably mouth-to-mouth if possible. 

y Call a poison control center or doctor for further treatment 

advice. 

NOTE TO PHYSICIAN 

Contains petroleum distillate. May pose an aspiration pneumonia hazard. 

Contains an organophosphate (profenofos) that inhibits cholinesterase. Consider 

taking venous blood for determination of blood cholinesterase activity (use heparin 

tube). Administer atropine sulfate, either by intramuscular or intravenously, dependant 

on severity of poisoning. Specific antidotes are oximes such as Pralidoxime (2-PAM). 

Avoid the use of opiates and phenothiazine. Carefully monitor patient because 

continued absorption of the poison may occur resulting in fatal relapse after initial 

improvement.

Have the product container or label with you when calling a poison control center or 

doctor or when going for treatment.

HOT LINE NUMBER 

For 24 Hour Medical Emergency Assistance (Human or Animal) or 

Chemical Emergency Assistance (Spill, Leak, Fire, or Accident), 

Call

1-800-888-8372
-3-

Engineering Controls Required

Closed System

x Mixers and loaders must use a closed mechanical transfer system that meets 

the requirements listed in the Worker Protection Standard (WPS) for 

agricultural pesticides [40 CFR 170.240(d) (4)] for providing dermal 

protection.

x The system must be capable of removing the pesticide from the shipping 

container and transferring it into mixing tanks and/or application equipment.

x At any disconnect point, the system must be equipped with a dry disconnect 

or dry couple shut-off device that is warranted by the manufacturer to 

minimize drippage to not more than 2 ml. per disconnect point.

x Mixers and loaders using the closed system must: wear the personal 

protective equipment required on this labeling for mixers/loaders; be provided, 

have immediately available, and wear in an emergency, such as a broken 

package, spill, or equipment breakdown, coveralls and chemical-resistant 

footwear.

Enclosed Cab Tractor 

x The applicator must use a tractor with an enclosed cab that meets the 

requirements listed in the Worker Protection Standard (WPS) for agricultural 

pesticides [40 CFR 170.240(d)(5)].

x Applicators must: 

o Be provided, have immediately available, and wear in an emergency 

when they must exit the cab within the treated area: coveralls, 

chemical-resistant gloves, and chemical-resistant footwear; 

o Take off any PPE that was worn in the treated area before reentering 

the cab; and 

x Store all such PPE in a chemical-resistant container, such as a plastic bag, to 

prevent contamination of the inside of the cab. 

PERSONAL PROTECTIVE EQUIPMENT (PPE) 

Some materials that are chemical-resistant to this product are barrier laminate, butyl 

rubber, nitrile rubber, and Viton®. If you want more options, follow the instructions for 

Category F on an EPA chemical –resistant category selection chart. 

Mixers, loaders, applicators, and other handlers using closed systems must wear:

x Long-sleeved shirt and long pants 

x Shoes plus socks 

x Chemical-resistant gloves 

x Chemical-resistant apron (for mixing and loading) 

x Protective eyewear 
-4-

When engaged in activities for which the use of engineering controls is not 

feasible, such as cleaning up a spill or leak or cleaning or repairing contaminated 

equipment, a worker must wear:

x Coveralls over long-sleeved shirt and long pants 

x Chemical-resistant gloves 

x Chemical-resistant footwear plus socks 

x Chemical-resistant apron 

x Protective eyewear 

Follow the manufacturer’s instructions for cleaning/maintaining PPE. If no such 

instructions exist, use detergent and hot water. Keep and wash PPE separately from 

other laundry. 

User Safety Recommendations 

Users should: 

x Wash hands before eating, drinking, chewing gum, using tobacco, or using the 

toilet.

x Remove clothing/PPE immediately if pesticide gets inside. Then wash 

thoroughly and put on clean clothing.

x Remove PPE immediately after handling this product. Wash the outside of 

gloves before removing. As soon as possible, wash thoroughly and change into 

clean clothing.

ADVISORY TO CERTIFIED CROP ADVISORS: Users should inform Certified Crop 

Advisors [as defined by the Worker Protection Standard (WPS)] that people engaged in 

scouting activities should wear coveralls over long pants and long-sleeved shirt, 

chemical-resistant footwear and socks, and chemical-resistant gloves made of any 

waterproof material when entering treated areas during the first 48 hours following 

application (72 hours in areas where the average rainfall is less than 25 inches per 

year).

ENVIRONMENTAL HAZARDS 

This pesticide is acutely toxic to fish and wildlife. Use with care when applying to areas 

frequented by wildlife or adjacent to any body of water. Due to the hazard to 

endangered fish, the application of this product is prohibited in Reeves County, TX and 

within one mile of the Dexter National Fish Hatchery in NM. For terrestrial uses, do not 

apply directly to water, or to areas where surface water is present, or to intertidal areas 

below the mean high water mark. Do not contaminate water by cleaning of equipment 

or disposing of equipment wash water. Because of the potential for surface water runoff 

from treated areas and the possibility of fish kills, do not apply to saturated soil, and do 

not treat while precipitation is occurring or while conditions favor runoff from the treated 

area.
-5-

This product is highly toxic to bees exposed to direct treatment on crops or weeds. Do 

not apply this product or allow it to drift to crops or weeds while bees are foraging in/or 

adjacent to the treatment area. Your Cooperative Agricultural Extension Service can 

provide additional information.

PHYSICAL AND CHEMICAL HAZARDS 

Flammable. Do not use or store near heat or open flame. 

DIRECTIONS FOR USE

It is a violation of Federal law to use this product in a manner inconsistent with its 

labeling. Apply this pesticide only as specified on this label. 

Do not apply this product in a way that will contact workers or other persons, either 

directly or through drift. Only protected handlers may be in the area during application. 

For any requirements specific to your State or Tribe, consult the agency responsible for 

pesticide regulation. 

AGRICULTURAL USE REQUIREMENTS 

Use this product only in accordance with its labeling and with the Worker Protection 

Standard, 40 CFR Part 170. This Standard contains requirements for the protection of 

agricultural workers on farms, forests, nurseries, and greenhouses, and handlers of 

agricultural pesticides. It contains requirements for training, decontamination, 

notification, and emergency assistance. It also contains specific instructions and 

exceptions pertaining to the statements on this label about personal protective 

equipment (PPE), notification to workers, and restricted-entry interval. The 

requirements in this box only apply to uses of this product that are covered by the 

Worker Protection Standard. 

Do not enter or allow worker entry into treated areas during the restricted-entry 

interval (REI) of 48 hours. The REI is 72 hours in areas where average rainfall is less 

than 25 inches per year. 

PPE required for early entry into treated areas that is permitted under the Worker 

Protection Standard and that involves contact with anything that has been treated, such 

as plants, soil, or water is: 

x Coveralls over long-sleeved shirt and long pants 

x Chemical-resistant gloves 

x Chemical-resistant footwear and socks 

x Protective eyewear 

Notify workers of the application by warning them orally and by posting warning signs at 

entrances to treated areas. 

FAILURE TO FOLLOW THE DIRECTIONS FOR USE AND PRECAUTIONS ON THIS 

LABEL MAY RESULT IN CROP INJURY, POOR PEST CONTROL, AND/OR 

ILLEGAL RESIDUES. 
-6-

PRODUCT USE INFORMATION AND REQUIREMENTS 

Curacron 8E Insecticide-Miticide is an emulsifiable concentrate that controls 

cotton bollworm, tobacco budworm, certain other listed insects, and mites on 

cotton. Best results can be expected from fields where Pest Management/ 

Scouting programs are used. 

Restrictions:

1. Application Equipment:

a. Apply only by enclosed cab ground application equipment. 

b. Do not apply by aerial application. 

2. Closed System Loading and Mixing:

Curacron 8E is sold in a container that contains no more than 10 gallons 

of the concentrated product. Closed system transfer (loading) of the 

product into the mix tank and closed system mixing is required. 

3. Maximum Amount per Day for Loaders and Mixers: Loaders and mixers are 

not allowed to handle more than 10 gallons of Curacron 8E per day.

4. Tractor Requirement: The applicator must use a tractor with an enclosed cab. 

5. Chemigation: Do not apply this product through any type of irrigation system. 

6. Buffer Zone Restrictions: Do not apply Curacron 8E within 100 ft of any body 

of water, including impounded waters, rivers, streams, lakes, and oceans. 

7. Harvesting: Cotton treated with this product must be mechanically harvested.

Hand harvesting is prohibited. 

Resistance Management 

Curacron 8E contains the Group 1B insecticide-miticide active ingredient, profenofos.

Profenofos belongs to the organophosphate class of chemistry, which has a specific 

mode of action and repeated use of organophosphates could result in the development 

of resistant strains of insects and/or mites. Development of resistance cannot be 

predicted. Therefore, Syngenta cannot assume liability for crop damage caused by 

resistant strains of insects and/or mites. If resistant strains are present, neither 

Curacron 8E nor any other Group 1B insecticide will effectively control these pests. The 

prompt use of other types of suitable insecticides should be considered. Consult your 

State Agricultural Experiment Station or Extension Service Specialist for information and 

guidance regarding resistance management in your area. 
-7-

MIXING

Precautions and Restrictions 

1. Prepare no more spray mixture than is needed for the immediate operation.

2. Thoroughly clean spray equipment before using this product.

3. Agitate thoroughly before and during application. Good bypass agitation is 

sufficient to keep Curacron 8E in emulsion.

4. Do not let spray mixture stand overnight in the spray tank.

5. Rinse spray tank at the end of the day. 

A. Curacron 8E Alone 

Mixing Instructions: 

1. Add 2/3 of the required amount of water to the spray tank with the agitator 

running, then add the desired amount of Curacron 8E.

2. Continue agitation while adding the remainder of the water. 

B. Curacron 8E - Tank Mixtures 

If using Curacron 8E in a tank mixture, the tank mix product must be approved for 

use on cotton. Observe all directions for use, use rates, dilution ratios, precautions, 

and limitations that appear on the tank mix product’s label. Do not exceed the 

maximum use rate, and follow the most restrictive label precautions and limitations 

on the Curacron 8E and the tank mix product’s label. Do not mix Curacron 8E with 

any product that prohibits such mixing. Tank mixtures or other applications of 

products referenced on this label are permitted only in those states in which use of 

the referenced products is approved.

x Compatibility: 

With Other Pesticides 

Curacron 8E is compatible with most commonly used agricultural pesticides 

and foliarly applied crop protection products; however, the crop safety of all 

potential tank mixes with Curacron 8E on cotton has not been tested. Before 

applying a tank mixture, treat a small area of the cotton field with the tank 

mixture to determine crop safety. 

With Foliar Fertilizers 

When tank mixed with Curacron 8E, some foliarly applied fertilizers can 

increase the chance of phytotoxicity or decrease the performance of Curacron 

8E. Syngenta is not responsible for the performance of Curacron 8E when 

tank mixed with foliarly applied fertilizers. 

x Tank Mixing Instructions 

1. Add 2/3 of the required amount of water to the mix tank.
-8-

2. Start the agitator running before adding any tank mix products. 

3. Add tank mix products in this order: products packaged in water-soluble 

packaging, wettable powders, wettable granules (dry flowables), liquid 

flowables, liquids and emulsifiable concentrates including Curacron 8E.

Allow the water-soluble packaging to completely dissolve and each product in 

the tank mix to completely disperse before adding the next tank mix product 

to the tank. 

4. Provide sufficient agitation while adding the remainder of the water.

5. Maintain agitation until all of the mixture has been applied. 

CROP USE DIRECTIONS

Apply Curacron 8E at the rates specified for the pests listed in the Application Rates 

Table. Curacron 8E can be diluted with water or oil; refer to the section, Application

Volume for instructions. 

Make the first application of Curacron 8E when pest populations reach economic 

thresholds. Economic thresholds will vary by locality. To determine economic 

thresholds in your area, contact your pest control advisor or cotton consultant. 

Based on scouting, repeat application at 5- to 7-day intervals, if needed; however, do 

not apply more than the maximum amount permitted per season.

A. Application Volume 

1. Curacron 8E Diluted With Water 

Mix the amount of Curacron 8E, specified in the Application Rates Table, with 

water and apply a minimum of 5 gallons of the finished solution/A.

NOTE: If the following conditions exist, apply Curacron 8E in a minimum of 3 

gallons of the finished solution/A to ensure maximum coverage of cotton foliage. 

x late season 

x heavy infestations 

x dense foliage and/or high temperatures

2. Curacron 8E Diluted with Oil (All cotton-growing states) 

Mix the amount of Curacron 8E, specified in the Application Rates Table, with oil 

following the mixture an application volume instructions in the table below.
-9-

Mixture Amount of Finished Solution to Use 

For ULV ground application, dilute 

Curacron 8E with once -refined 

vegetable oil

Apply 1-2 qt of finished solution/A 

Curacron 8E + water + emulsified 

vegetable oil 

Add 1-2 pt of emulsified vegetable oil as 

an additive. Apply a minimum of 1 

gallon of this mixture/A 

B. Application Rates Table 

Pests 

Where Curacron 

8E Can Be 

Applied

Amount of 

Curacron 8E to 

Apply Instructions 

Aphids1 All cotton-growing 

states

1/2 pt/A Single maximum application rate 

is 0.5 pt product/A (0.5 lb ai/A). 

Minimum application interval is 5 

days. Maximum amount is 5.0 pt 

product/A/season (5 lb 

ai/A/season). When diluted with 

water, Pre-Harvest Interval (PHI) 

is 14 days. When diluted with oil, 

PHI is 30 days. 

Plant bugs1

Lygus bugs1*

All cotton-growing 

states.

*In AZ and CA, 

Curacron only 

provides 

suppression of 

Lygus bugs. 

1/4 to 1/2 pt/A Single maximum application rate 

is 0.5 pt product/A (0.5 lb ai/A). 

Minimum application interval is 5 

days. Maximum amount is 5.0 pt 

product/A/season (5 lb 

ai/A/season. When diluted with 

water, Pre-Harvest Interval (PHI) 

is 14 days. When diluted with oil, 

PHI is 30 days. 

Cotton bollworm All cotton-growing 

states except AZ 

and CA 

1/8 to 1/4 pt/A Curacron 8E kills cotton bollworm 

eggs on contact; use the higher 

rate if plant bugs are also present. 

Single maximum application rate 

is 0.5 pt product/A (0.5 lb ai/A). 

Minimum application interval is 5 

days. Maximum amount is 5.0 pt 

product/A/season (5 lb 

ai/A/season). When diluted with 

water, Pre-Harvest Interval (PHI) 

is 14 days. When diluted with oil, 

PHI is 30 days. 
-10-

Tobacco 

budworm1

All cotton-growing 

states except AZ 

and CA 

1/4 pt/A Curacron 8E kills tobacco 

budworm eggs on contact but 

does not control tobacco 

budworm larvae. 

Single maximum application rate 

is 0.5 pt product/A (0.5 lb ai/A). 

Minimum application interval is 5 

days. Maximum amount is 5.0 pt 

product/A/season (5 lb 

ai/A/season). When diluted with 

water, Pre-Harvest Interval (PHI) 

is 14 days. When diluted with oil, 

PHI is 30 days. 

Cotton bollworm 

Tobacco 

 budworm1

AZ and CA 1/2 pt./A 

This application rate is only 

effective for light infestations. 

Single maximum application 

rate is 0.5 pt product/A (0.5 

lb ai/A). Minimum 

application interval is 5 days. 

Maximum amount is 5.0 pt 

product/A/season (5 lb 

ai/A/season). When diluted 

with water, Pre-Harvest 

Interval (PHI) is 14 days.

When diluted with oil, PHI is 

30 days. 

Mites All cotton-growing 

states 

1/2 pt/A Begin applications when 

mites first appear. 

Single maximum application 

rate is 0.5 pt product/A (0.5 

lb ai/A). Minimum 

application interval is 5 days. 

Maximum amount is 5.0 pt 

product/A/season (5 lb 

ai/A/season). When diluted 

with water, Pre-Harvest 

Interval (PHI) is 14 days.

When diluted with oil, PHI is 

30 days. 

1 See Resistance Management in the PRODUCT USE INFORMATION AND 

REQUIREMENTS section.

Use Restrictions:

x Application Method:

x Apply only by enclosed cab ground application equipment. 

x Do not apply by aerial application. 

x Crop Injury Precautions: Curacron 8E may cause spotting or reddening of cotton 

leaves. Avoid spray overlap because crop injury may result. 

x Harvesting: Cotton treated with Curacron 8E must be mechanically harvested; 

harvesting by hand is prohibited. 
-11-

x Grazing Restrictions:

o Do not allow livestock to graze treated cotton. 

o Do not feed gin trash or foliage from treated cotton plants to livestock. 

x Rotational Crops: Cotton fields treated with Curacron 8E can be rotated to other 

crops 30 days after the last application. 

STORAGE AND DISPOSAL 

Do not contaminate water, food, or feed by storage and disposal. 

Pesticide Storage 

Store the product in a dry, cool, and ventilated area. Keep container closed. 

Pesticide Disposal 

Pesticide wastes are toxic. Improper disposal of excess pesticide, spray mixture, or 

rinsate is a violation of federal law. If these wastes cannot be disposed of by use 

according to label instructions, contact your State Pesticide or Environmental Control 

Agency or the Hazardous Waste Representative at the nearest EPA Regional Office for 

guidance.

Container Handling (10 gallon maximum net content)

This is a non-refillable closed system container. Do not reuse or refill this container.

Syngenta’s authorized agent will pick up the empty container and handle its disposal. 

Contact Syngenta or its authorized agent to make arrangements for this service and 

store the empty container in a secure area until pick up.

Cleaning the container before final disposal is the responsibility of the person disposing 

of the container. To clean the container before final disposal, triple rinse the container 

as follows: empty the remaining contents into a rinsate collection system. and drain for 

10 seconds after the flow begins to drip. Fill the container 1⁄4 full with water. Replace 

and tighten closures. Tip container on its side and roll it back and forth for 30 seconds 

ensuring at least one complete revolution. Stand the container on its end and tip it back 

and forth several times. Empty the rinsate into a rinsate collection system or store 

rinsate for later disposal. Repeat this procedure two more times. Then offer for 

recycling, if available, or puncture and dispose of in a sanitary landfill, or by incineration, 

or, by other procedures allowed by state and local authorities.
-12-

CONDITIONS OF SALE AND LIMITATION OF WARRANTY AND LIABILITY 

NOTICE: Read the entire Directions for Use and Conditions of Sale and Limitation of 

Warranty and Liability before buying or using this product. If the terms are not 

acceptable, return the product at once, unopened, and the purchase price will be 

refunded.

The Directions for Use of this product must be followed carefully. It is impossible to 

eliminate all risks inherently associated with the use of this product. Crop injury, 

ineffectiveness or other unintended consequences may result because of such factors 

as manner of use or application, weather or crop conditions, presence of other materials 

or other influencing factors in the use of the product, which are beyond the control of 

SYNGENTA CROP PROTECTION, LLC or Seller. To the extent permitted by 

applicable law, Buyer and User agree to hold SYNGENTA and Seller harmless for any 

claims relating to such factors. 

SYNGENTA warrants that this product conforms to the chemical description on the label 

and is reasonably fit for the purposes stated in the Directions for Use, subject to the 

inherent risks referred to above, when used in accordance with directions under normal 

use conditions. To the extent permitted by applicable law: (1) this warranty does not 

extend to the use of the product contrary to label instructions, or under conditions not 

reasonably foreseeable to or beyond the control of Seller or SYNGENTA, and (2) Buyer 

and User assume the risk of any such use. TO THE EXTENT PERMITTED BY 

APPLICABLE LAW, SYNGENTA MAKES NO WARRANTIES OF MERCHANTABILITY 

OR OF FITNESS FOR A PARTICULAR PURPOSE NOR ANY OTHER EXPRESS OR 

IMPLIED WARRANTY EXCEPT AS WARRANTED BY THIS LABEL. 

To the extent permitted by applicable law, in no event shall SYNGENTA be liable for 

any incidental, consequential or special damages resulting from the use or handling of 

this product. TO THE EXTENT PERMITTED BY APPLICABLE LAW, THE 

EXCLUSIVE REMEDY OF THE USER OR BUYER, AND THE EXCLUSIVE LIABILITY 

OF SYNGENTA AND SELLER FOR ANY AND ALL CLAIMS, LOSSES, INJURIES 

OR DAMAGES (INCLUDING CLAIMS BASED ON BREACH OF WARRANTY, 

CONTRACT, NEGLIGENCE, TORT, STRICT LIABILITY OR OTHERWISE) 

RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT, SHALL BE THE 

RETURN OF THE PURCHASE PRICE OF THE PRODUCT OR, AT THE ELECTION 

OF SYNGENTA OR SELLER, THE REPLACEMENT OF THE PRODUCT. 

SYNGENTA and Seller offer this product, and Buyer and User accept it, subject to the 

foregoing Conditions of Sale and Limitation of Warranty and Liability, which may not be 

modified except by written agreement signed by a duly authorized representative of 

SYNGENTA. 
-13-

Curacron®, the ALLIANCE FRAME, the Syngenta logo, and the PURPOSE ICON are 

trademarks of a Syngenta Group Company. 

Viton® is a registered trademark of E.I. DuPont de Nemours and Company 

©2014 Syngenta 

For non-emergency (e.g., current product information), call 

Syngenta Crop Protection at 1-800-334-9481. 

Manufactured for: 

Syngenta Crop Protection, LLC 

P.O. Box 18300 

Greensboro, North Carolina 27419-8300 

SCP 669 MAS 0509 
-14-

(Non-detachable container label / net contents 10 gallons maximum)

RESTRICTED USE PESTICIDE 

FOR RETAIL SALE TO AND USE ONLY BY 

CERTIFIED APPLICATORS OR PERSONS 

UNDER THEIR DIRECT SUPERVISION, AND ONLY 

FOR THOSE USES COVERED BY THE 

CERTIFIED APPLICATOR’S CERTIFICATION 

DUE TO HIGH TOXICITY 

Curacron® 8E Insecticide-Miticide 

Group 1B Insecticide

For insect and mite control in cotton 

Closed System Loading and Mixing and Enclosed Tractor Cab Required 

Active Ingredient: 

Profenofos1

 ................................................................................................. 73.0%* 

Other Ingredients**: 27.0% 

Total: 100.0% 

1

CAS No. 41198-08-7 

*1 gallon contains 8 lb of profenofos. 

**Contains petroleum distillates 

KEEP OUT OF REACH OF CHILDREN. 

CAUTION

Si usted no entiende la etiqueta, busque a alguien para que se la explique a usted en 

detalle. (If you do not understand the label, find someone to explain it to you in detail.) 

See additional precautionary statements and directions for use in booklet. 

EPA Reg. No. 100-669 

EPA Est. xxxxx

SCP 669 MAS 0509 

10 gallons 

Net Contents 
-15-

PRECAUTIONARY STATEMENTS 

HAZARDS TO HUMANS AND DOMESTIC ANIMALS 

CAUTION

Harmful if swallowed. Harmful if absorbed through skin. Causes moderate eye 

irritation. Avoid contact with skin, eyes, or clothing. Prolonged or frequently repeated 

skin contact may cause allergic reactions in some individuals. 

FIRST AID 

This product contains an organophosphate that inhibits cholinesterase

If swallowed x Immediately call a poison control center or doctor

x Do not induce vomiting unless told to by a poison control 

center or doctor.

x Do not give any liquid to the person. 

x Do not give anything by mouth to an unconscious person. 

If on skin or 

clothing

x Take off contaminated clothing 

x Rinse skin immediately with plenty of water for 15 – 20 

minutes.

x Call a poison control center or doctor for treatment advice.

If in eyes x Hold eye open and rinse slowly and gently with water for 

15-20 minutes.

x Remove contact lenses, if present, after the first 5 minutes, 

then continue rinsing eye.

x Call a poison control center or doctor for treatment advice. 

If Inhaled x Move person to fresh air 

x If person is not breathing, call 911 or ambulance, then give 

artificial respiration, preferably mouth-to-mouth if possible 

x Call a poison control center or doctor for further treatment 

advice. 

NOTE TO PHYSICIAN 

Contains petroleum distillate. May pose an aspiration pneumonia hazard. 

Contains an organophosphate (profenofos) that inhibits cholinesterase. Consider 

taking venous blood for determination of blood cholinesterase activity (use 

heparin tube). Administer atropine sulfate, either by intramuscular or 

intravenously, dependant on severity of poisoning. Specific antidotes are oximes 

such as Pralidoxime (2-PAM). Avoid the use of opiates and phenothiazine.

Carefully monitor patient because continued absorption of the poison may occur 

resulting in fatal relapse after initial improvement.

Have the product container or label with you when calling a poison control center 

or doctor or when going for treatment.

HOT LINE NUMBER 

For 24-Hour Medical Emergency Assistance (Human or Animal) or 

Chemical Emergency Assistance (Spill, Leak, Fire, or Accident), 

Call

1-800-888-8372
-16-

ENVIRONMENTAL HAZARDS 

Apply this pesticide only as specified on this label. This pesticide is acutely toxic to fish 

and wildlife. Use with care when applying to areas frequented by wildlife or adjacent to 

any body of water. Due to the hazard to endangered fish, the application of this product 

is prohibited in Reeves County, TX and within one mile of the Dexter National Fish 

Hatchery in NM. For terrestrial uses, do not apply directly to water, or to areas where 

surface water is present, or to intertidal areas below the mean high water mark. Do not 

contaminate water by cleaning of equipment or disposing of equipment wash water.

Because of the potential for surface water runoff from treated areas and the possibility 

of fish kills, do not apply to saturated soil and do not treat while precipitation is occurring 

or while conditions favor runoff from the treated area.This product is highly toxic to bees 

exposed to direct treatment on crops or weeds. Do not apply this product or allow it to 

drift to crops or weeds while bees are foraging in/or adjacent to the treatment area.

Additional information may be obtained from your Cooperative Agricultural Extension 

Service can provide additional information. 

DIRECTIONS FOR USE 

It is a violation of Federal law to use this product in a manner inconsistent with its 

labeling. 

FAILURE TO FOLLOW THE DIRECTIONS FOR USE AND PRECAUTIONS ON THIS 

LABEL MAY RESULT IN CROP INJURY, POOR PEST CONTROL, AND/OR 

ILLEGAL RESIDUES. 

AGRICULTURAL USE REQUIREMENTS 

Use this product only in accordance with its labeling and with the Worker Protection 

Standard, 40 CFR Part 170. Refer to supplemental labeling under “Agricultural Use 

Requirements” in the Directions for Use section for information about this standard. 

Chemigation Restriction: Do not apply this product through any type of irrigation 

system.
-17-

STORAGE AND DISPOSAL 

Do not contaminate water, food, or feed by storage and disposal. 

Pesticide Storage 

Store the product in a dry, cool, and ventilated area. Keep container closed. 

Pesticide Disposal 

Pesticide wastes are toxic. Improper disposal of excess pesticide, spray mixture, or 

rinsate is a violation of federal law. If these wastes cannot be disposed of by use 

according to label instructions, contact your State Pesticide or Environmental Control 

Agency or the Hazardous Waste Representative at the nearest EPA Regional Office for 

guidance.

Container Handling (10 gallon maximum net content)

This is a non-refillable closed system container. Do not reuse or refill this container. 

Syngenta’s authorized agent will pick up the empty container and handle its disposal. 

Contact Syngenta or its authorized agent to make arrangements for this service and 

store the empty container in a secure area until pick up.

Cleaning the container before final disposal is the responsibility of the person disposing 

of the container. To clean the container before final disposal, triple rinse the container 

as follows: empty the remaining contents into a rinsate collection system and drain for 

10 seconds after the flow begins to drip. Fill the container 1⁄4 full with water. Replace 

and tighten closures. Tip container on its side and roll it back and forth for 30 seconds 

ensuring at least one complete revolution. Stand the container on its end and tip it back 

and forth several times. Empty the rinsate into a rinsate collection system or store 

rinsate for later disposal. Repeat this procedure two more times. Then offer for 

recycling, if available, or puncture and dispose of in a sanitary landfill, or by incineration, 

or, by other procedures allowed by state and local authorities 
-18-

CONDITIONS OF SALE AND LIMITATION OF WARRANTY AND LIABILITY 

NOTICE: Read the entire Directions for Use and Conditions of Sale and Limitation of 

Warranty and Liability before buying or using this product. If the terms are not 

acceptable, return the product at once, unopened, and the purchase price will be 

refunded.

The Directions for Use of this product must be followed carefully. It is impossible to 

eliminate all risks inherently associated with the use of this product. Crop injury, 

ineffectiveness or other unintended consequences may result because of such factors 

as manner of use or application, weather or crop conditions, presence of other materials 

or other influencing factors in the use of the product, which are beyond the control of 

SYNGENTA CROP PROTECTION, LLC or Seller. To the extent permitted by 

applicable law, Buyer and User agree to hold SYNGENTA and Seller harmless for any 

claims relating to such factors. 

SYNGENTA warrants that this product conforms to the chemical description on the label 

and is reasonably fit for the purposes stated in the Directions for Use, subject to the 

inherent risks referred to above, when used in accordance with directions under normal 

use conditions. To the extent permitted by applicable law: (1) this warranty does not 

extend to the use of the product contrary to label instructions, or under conditions not 

reasonably foreseeable to or beyond the control of Seller or SYNGENTA, and (2) Buyer 

and User assume the risk of any such use. TO THE EXTENT PERMITTED BY 

APPLICABLE LAW, SYNGENTA MAKES NO WARRANTIES OF MERCHANTABILITY 

OR OF FITNESS FOR A PARTICULAR PURPOSE NOR ANY OTHER EXPRESS OR 

IMPLIED WARRANTY EXCEPT AS WARRANTED BY THIS LABEL. 

To the extent permitted by applicable law, in no event shall SYNGENTA be liable for 

any incidental, consequential or special damages resulting from the use or handling of 

this product. TO THE EXTENT PERMITTED BY APPLICABLE LAW, THE EXCLUSIVE 

REMEDY OF THE USER OR BUYER, AND THE EXCLUSIVE LIABILITY OF 

SYNGENTA AND SELLER FOR ANY AND ALL CLAIMS, LOSSES, INJURIES OR 

DAMAGES (INCLUDING CLAIMS BASED ON BREACH OF WARRANTY, 

CONTRACT, NEGLIGENCE, TORT, STRICT LIABILITY OR OTHERWISE) 

RESULTING FROM THE USE OR HANDLING OF THIS PRODUCT, SHALL BE THE 

RETURN OF THE PURCHASE PRICE OF THE PRODUCT OR, AT THE ELECTION 

OF SYNGENTA OR SELLER, THE REPLACEMENT OF THE PRODUCT. 

SYNGENTA and Seller offer this product, and Buyer and User accept it, subject to the 

foregoing Conditions of Sale and Limitation of Warranty and Liability, which may not be 

modified except by written agreement signed by a duly authorized representative of 

SYNGENTA. 

____________________________________________________________________

Curacron® and the Syngenta logo are trademarks of a Syngenta Group Company 

©2014 Syngenta 
-19-

Manufactured for: 

Syngenta Crop Protection, LLC 

P.O. Box 18300 

Greensboro, North Carolina 27419-8300 

SCP 669 MAS 0509 

Curacron 669 MAS 0509 AMEND DEC2010-HI Version B – pl – 5/6/14 

000100-00669.20140506.CURACRON_AMEND_DEC2010B-HI.pdf 

Curacron 669 MAS 0509 AMEND DEC2010-HI Version C – pl – 5/12/14 

000100-00669.20140512.CURACRON_AMEND_DEC2010C-HI.pdf 

Curacron 669 MAS 0509 AMEND DEC2010-HI Version D – pl – 6/26/14 

000100-00669.20140626.CURACRON_AMEND_DEC2010D-HI.pdf 

Curacron 669 MAS 0509 AMEND DEC2010-HI Version E – pl – 7/7/14 

000100-00669.20140707.CURACRON_AMEND_DEC2010E-HI.pdf 

Curacron 669 MAS 0509 AMEND DEC2010-CLEAN Version E – pl – 7/7/14 

000100-00669.20140707.CURACRON_AMEND_DEC2010E.pdf