Exhibit 10.27

 

Translation for information purposes only

 




 

Amendment to the Services Agreement

 

relating to the SARA-DATA Clinical Data Platform

 

 

Between

 

Biophytis SA

 

as Client

 

and

 

BlueCompanion

 

as Service Provider

 




 

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TABLE OF CONTENTS

 

	
1
    	
DEFINITIONS -   INTERPRETATION
    	
4
    
	
 
    	
 
    	
 
    
	
2
    	
MODIFICATIONS MADE   TO THE CONTRACT
    	
4
    
	
 
    	
 
    	
 
    
	
3
    	
ABSENCE OF OTHER   MODIFICATIONS
    	
4
    
	
 
    	
 
    	
 
    
	
4
    	
ABSENCE OF NOVATION
    	
4
    
	
 
    	
 
    	
 
    
	
5
    	
ENTRY INTO FORCE
    	
4
    
	
 
    	
 
    	
 
    
	
6
    	
INVALIDITY OF A   STIPULATION
    	
4
    


 

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THIS AMENDMENT IS ENTERED INTO ON 26 NOVEMBER 2018:

 

BETWEEN

 

(1)                         Biophytis SA, a public limited company with share capital of EUR 2,692,682.60, having its registered office located at 14 avenue de l’Opéra, 75001 Paris, registered in the Trade and Companies Register of Paris under number 492.002.225 and represented by Mr Stanislas Veillet, duly authorised for the purposes hereof (hereinafter the “Client”)

 

and

 

(2)                         BlueCompanion Ltd, a company under English law, having its registered office located at Carlyle House, Lower Ground Floor, 235-237 Vauxhall Bridge Road, London, England SW1V 1EJ, United Kingdom, registered under number 9648211, represented by Mrs Susanna Del Signore, duly authorised for the purposes hereof (hereinafter the “Service Provider”).

 

The Client and the Service Provider are hereinafter collectively referred to as the Parties and individually as a Party.

 

THE FOLLOWING WAS SET FORTH BEFOREHAND

 

(A)                       The Client is a company specialising in biomedical research and the development of health products (nutraceuticals and medicines). The Client has developed a portfolio of candidate drugs at different stages of development that address age-related degeneration pathologies.

 

(B)                       One of the candidate drugs being developed, named Sarconeos, concerns sarcopenia (skeletal muscle degeneration). The preparation of the clinical study of Phase 2b of Sarconeos is in progress, including, among other things, a study for characterisation and preselection of the target population in four (4) countries (Belgium, France, Italy and the United States) (hereinafter the “SARA-OBS Study”).

 

(C)                       The Service Provider is a company that offers services in connection with the implementation of clinical trials.

 

(D)                       The Parties wanted to establish a technological partnership in order to achieve the creation of a digital platform in connection with the clinical development of Sarconeos, and in particular the SARA-OBS Study (BIO101-CL02), allowing the Client to collect and analyse the clinical data relating to Sarconeos (hereinafter the  “SARA-DATA Clinical Data Platform”).

 

(E)                        Starting from October 2016, the Service Provider began to carry out services in order to implement and develop the SARA-DATA Clinical Data Platform. To this end, 16 May 2017 the Parties entered into a service-providing agreement in order to formalise their contractual relationship and to specify the terms and conditions for implementation of the development of the SARA-DATA Clinical Data Platform (hereinafter the “Agreement”).

 

(F)                         By an amendment (the “First amendment”) dated 22 December 2017, the Parties modified (i) Articles 1 and 5 of the Agreement dated 16 May 2017, (ii) the specifications, (iii) the budget, and (iv) the duration of the Agreement.

 

(G)                       The Parties now wish to modify (i) the specifications, (ii) the budget and (iii) the duration of the Agreement.

 

(H)                      As a result of the preceding, the Parties have agreed to sign this amendment to the Agreement (the “Amendment”).

 

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THIS HAVING BEEN SET FORTH, THE FOLLOWING WAS AGREED AND DECIDED:

 

1                                DEFINITIONS - INTERPRETATION

 

For the purposes of this Amendment, capitalised terms and expressions have the meaning that they are given in the Agreement, unless otherwise defined in this Amendment.

 

2                                MODIFICATIONS MADE TO THE CONTRACT

 

2.1                      Modification of Article 8 of the Convention

 

By this Amendment, the Parties agree to modify Article 8 of the Agreement, which will henceforth be worded as follows:

 

·                                 DURATION

 

8.1                      The Agreement is entered into on the date hereof with retroactive effect from the 1st of July 2016 and ends on 31 October 2019.”

 

2.2                      Modification of Annex 1 of the Agreement and the First Amendment

 

By this Amendment, the Parties agree to modify the entire Annex 1 of Article 2 of the Agreement, and Annex 2 of the First Amendment, specifying the specifications and the budget, the new version of which is enclosed as Appendix 1 of the Amendment.

 

3                                ABSENCE OF OTHER MODIFICATIONS

 

3.1                      The Parties expressly agree that with the sole exception of the modifications expressly made to the stipulations of the Agreement under the conditions referred to above, all other stipulations of the Agreement and the First Amendment remain unchanged and in full force.

 

3.2                      Any reference to the Agreement and the First Amendment must be understood as a reference to the Agreement modified by this Amendment.

 

3.3                      Unless otherwise stipulated in this Amendment, the Agreement and the First Amendment remain in full force, and from the date of signing of the Amendment, the Agreement, the First Amendment and this Amendment must be read and interpreted as forming a single document.

 

4                                ABSENCE OF NOVATION

 

4.1                      With the exception of what is expressly stipulated in Article 2 of the above Amendment, this amendment does not implement any novation concerning the terms and conditions of the Agreement.

 

4.2                      This condition is an essential and determining condition for the Parties’ consent, without which they would not have signed the Amendment.

 

5                                ENTRY INTO FORCE

 

The Amendment will enter into force on 1 August 2018.

 

6                                INVALIDITY OF A STIPULATION

 

If one of the provisions of the Amendment proves to be or becomes invalid, unenforceable, void, illegal or inapplicable, this cannot call into question the validity, opposability or enforceability of the other provisions of the Amendment, which will not be affected or altered in any manner by it, and the Parties will not be exempt from carrying out the Amendment.

 

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Drawn up in Paris

 

On  December 7, 2018

 

In two (2) originals

 

 

	
/s/ Stanislas Veillet
    	
 
    	
/s/ Susanna Del Signore
    
	
Biophytis SA
    	
 
    	
BlueCompanion
    
	
Represented   by Mr Stanislas Veillet
    	
 
    	
Represented   by Ms Susanna Del Signore
    


 

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Annex 1:

 

Amended Service Proposal of 20/07/2018:

 

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