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                    Most Recent Reports**1 - 20 of 372 Reports**
	
	

	
	  **Released on   Mar 18, 2024**
          SUPPLEMENTAL MATERIAL FOR GAO-24-106446: Strengthening Coordination and Monitoring of Autism Activities in the Federal Government
    GAO-24-107314
      Published:   Mar 18, 2024
. 
        Publicly Released:   Mar 18, 2024
.
    The National Institutes of Health helps coordinate federal agencies' activities that promote the health and well-being of people with autism. We reported that NIH has followed several practices to help these agencies work well together. But it could be doing more, and we recommend ways to help. This is an "Easy Read" version of our report. Easy Read is a way some groups make their...
      **Released on   Feb 29, 2024**
          Biomedical Research: Actions Needed to Adopt Collaboration Practices to Address Research Duplication
    GAO-24-106757
      Published:   Feb 29, 2024
. 
        Publicly Released:   Feb 29, 2024
.
    The federal government has long invested in biomedical research through different Department of Health and Human Services agencies. This report, the first in a series, looks at potential duplication of research efforts across four such agencies. The agencies have practices in place to avoid unnecessary research duplication. For example, agency staff regularly meet to share priorities and identify duplicative work. In addition, the newest health...
      **Released on   Feb 28, 2024**
          Autism Research and Support Services: Federal Interagency Coordination and Monitoring Efforts Could Be Further Strengthened
    GAO-24-106446
      Published:   Feb 28, 2024
. 
        Publicly Released:   Feb 28, 2024
.
    We also published an " Easy Read " version of this report. Easy Read is a way of making written information easier to understand. We published the Easy Read version to make our report more accessible to certain people with autism and other intellectual and developmental disabilities. To promote the health and well-being of people with autism, the National Institutes of Health helps coordinate the...
      **Released on   Sep 29, 2023**
          Antiviral Drugs: Economic Incentives and Strategies for Pandemic Preparedness [Reissued with revisions on Sept. 29, 2023]
    GAO-23-105847
      Published:   Sep 29, 2023
. 
        Publicly Released:   Sep 29, 2023
.
    Scientists have predicted that another pandemic is likely. They've identified the viruses that might cause it—although the Department of Health and Human Services told us that few antiviral drugs for those viruses have been approved or are in HHS-funded clinical trials. Our panel of experts suggested several ways for policymakers to incentivize the development of these antiviral drugs, such as research grants or commitments to...
      **Released on   Jun 22, 2023**
          Data Science: NIH Needs to Implement Key Workforce Planning Activities
    GAO-23-105594
      Published:   Jun 22, 2023
. 
        Publicly Released:   Jun 22, 2023
.
    The National Institutes of Health—a leader in the support of biomedical research—faces a shortage of employees with data science expertise. NIH needs this expertise to handle the growing amount of increasingly complex data from advances in research. NIH plans to enhance its data science workforce, but it hasn't examined the skills of existing staff to determine what it needs to reach its goals. Until NIH...
      **Released on   May 4, 2023**
          National Institutes of Health: Better Data Will Improve Understanding of Federal Contributions to Drug Development
    GAO-23-105656
      Published:   Apr 4, 2023
. 
        Publicly Released:   May 4, 2023
.
    The National Institutes of Health—the largest public funder of biomedical research in the U.S.—invests billions of dollars each year to help develop new drugs or new uses for existing drugs. But the extent of NIH's contributions to drug development isn't well understood or recognized by the public. One reason may be that recipients of NIH funds aren't always disclosing agency support fully or correctly when...
      **Released on   Mar 30, 2023**
          Animal Use in Research: NIH Should Strengthen Oversight of Projects It Funds at Foreign Facilities
    GAO-23-105736
      Published:   Mar 30, 2023
. 
        Publicly Released:   Mar 30, 2023
.
    The National Institutes of Health provided $2.2 billion in contracts or grants in FYs 2011-2021 to foreign organizations for research involving animals. Foreign facilities conducting this research must follow U.S. or international animal welfare standards. NIH relies on annual reports submitted by funding recipients to monitor the foreign research facilities' compliance with these standards. But NIH doesn't verify the reliability of the information in these...
      **Released on   Dec 15, 2022**
          CARES Act: Structural Characteristics That Can Help Insulate HHS Agencies against Potential Political Interference
    GAO-23-105415
      Published:   Dec 15, 2022
. 
        Publicly Released:   Dec 15, 2022
.
    Four HHS agencies had key roles in the federal COVID-19 response. Our prior reports noted shortcomings to that response, including possible political interference. Some characteristics of an agency's structure may affect how insulated it is from potential political interference, including How many political appointees it has Whether it has active advisory committees with experts to guide decisions If agency officials have fixed terms These characteristics...
      **Released on   Sep 29, 2022**
          Federal Research: Information on Funding for U.S.-China Research Collaboration and Other International Activities
    GAO-22-105313
      Published:   Sep 29, 2022
. 
        Publicly Released:   Sep 29, 2022
.
    The U.S. government sometimes supports international research collaborations by providing funding to foreign entities—such as universities and public health organizations. This also gives U.S. researchers access to global scientific resources. From FY 2015 to 2021, federal agencies provided $28.9 million directly to Chinese entities for research and development activities. For example, the Centers for Disease Control and Prevention and National Institutes of Health awarded funds...
      **Released on   Jul 28, 2022**
          Research Reliability: Federal Actions Needed to Promote Stronger Research Practices
    GAO-22-104411
      Published:   Jul 28, 2022
. 
        Publicly Released:   Jul 28, 2022
.
    While scientific discoveries can be serendipitous, reliable research is more often built on successive studies that employ rigorous design, documentation, and confirmation. The U.S. government funded over $42 billion in science research in 2019. How can federal agencies help assure the reliability of that research? Experts and others have suggested that agencies implement practices such as disclosing results and methods earlier, as well as incentivizing...
      **Released on   Apr 29, 2022**
          Scientific Integrity: HHS Agencies Need to Develop Procedures and Train Staff on Reporting and Addressing Political Interference
    GAO-22-105885
      Published:   Apr 29, 2022
. 
        Publicly Released:   Apr 29, 2022
.
    Public health agencies regularly use scientific methods and evidence to inform decisions. How do they protect scientific decision-making from interference for political purposes? We testified that the policies and procedures for ensuring scientific integrity at 4 agencies we reviewed do not define political interference or describe how it should be reported and addressed. Employees said they observed potential political interference but didn't report it because...
      **Released on   Apr 20, 2022**
          Scientific Integrity: HHS Agencies Need to Develop Procedures and Train Staff on Reporting and Addressing Political Interference
    GAO-22-104613
      Published:   Apr 20, 2022
. 
        Publicly Released:   Apr 20, 2022
.
    Public health agencies regularly use scientific methods and evidence to inform decisions. How do they protect scientific decision-making from being interfered with for political purposes? The policies and procedures for ensuring scientific integrity at 4 agencies we reviewed do not define political interference or describe how it should be reported and addressed. Employees told us they observed potential political interference but they didn't report it...
      **Released on   Dec 7, 2021**
          Cybersecurity: NIH Needs to Take Further Actions to Resolve Control Deficiencies and Improve Its Program
    GAO-22-104467
      Published:   Dec 7, 2021
. 
        Publicly Released:   Dec 7, 2021
.
    The National Institutes of Health's duties include researching infectious diseases and administering over $30 billion a year in research grants. NIH uses IT systems containing sensitive data to carry out its mission. This report is a public version of our June 2021 report on NIH cybersecurity. The agency has taken actions intended to safeguard the confidentiality, integrity, and availability of its systems. However, we found...
      **Released on   Nov 16, 2021**
          Vaccine Development: Capabilities and Challenges for Addressing Infectious Diseases
    GAO-22-104371
      Published:   Nov 16, 2021
. 
        Publicly Released:   Nov 16, 2021
.
    The CARES Act requires GAO to look at the government's response to the COVID-19 pandemic, including vaccine development. Vaccines prepare the body to respond quickly to an infection and play a key role in keeping people and global communities healthy. Overall, vaccine development is still difficult, complex, and costly. But we identified 16 innovative technologies and approaches that may enhance the nation's ability to respond...
      **Released on   Oct 5, 2021**
          Federal Research: Agency Actions Needed to Address Foreign Influence
    GAO-22-105434
      Published:   Oct 5, 2021
. 
        Publicly Released:   Oct 5, 2021
.
    To protect U.S. investments in scientific research from undue foreign influence, federal agencies should have conflict of interest policies and require researchers to disclose foreign interests. We testified that the National Science Foundation has an agency-wide financial conflict of interest policy, but it doesn't define non-financial conflicts (e.g., for researchers with multiple professional appointments). The policy does require researchers to disclose some non-financial interests in...
      **Released on   Apr 22, 2021**
          Federal Research: NIH Should Take Further Action to Address Foreign Influence
    GAO-21-523T
      Published:   Apr 22, 2021
. 
        Publicly Released:   Apr 22, 2021
.
    The National Institutes of Health is a major source of research funding for U.S. universities. It has raised concerns over the fruits of this funding going abroad and undisclosed conflicts of interest. For example, in 2020, investigators found a U.S. university researcher involved in a Chinese-government talent recruitment program failed to disclose hundreds of thousands of dollars in foreign income. We testified that, among other...
      **Released on   Mar 31, 2021**
          Biomedical Research: Information on Federal Contributions to Remdesivir
    GAO-21-272
      Published:   Mar 31, 2021
. 
        Publicly Released:   Mar 31, 2021
.
    Remdesivir was the first drug approved by the Food and Drug Administration to treat COVID-19 . Gilead Sciences, Inc., originally developed it to treat other viral diseases. We reviewed federal contributions to development of remdesivir and related agency patent rights. As of Dec. 2020, federal funding for preclinical studies and clinical trials involving remdesivir totaled about $162 million. The federal contributions did not result in...
      **Released on   Nov 20, 2020**
          Biomedical Research: NIH Should Publicly Report More Information about the Licensing of Its Intellectual Property
    GAO-21-52
      Published:   Oct 22, 2020
. 
        Publicly Released:   Nov 20, 2020
.
    Federal research and inventions can contribute to the development of life-saving drugs, vaccines, and medical devices. One way this happens is that the National Institutes of Health licenses its intellectual property to private companies that have the resources to bring products to market. NIH received up to $2 billion in royalties from its contributions to 34 drugs sold from 1991-2019. But how does licensing support...
      **Released on   Sep 16, 2020**
          Private Health Coverage: Results of Covert Testing for Selected Offerings
    GAO-20-634R
      Published:   Aug 24, 2020
. 
        Publicly Released:   Sep 16, 2020
.
    Our undercover agents conducted 31 tests on health insurance sales representatives to gauge their use of deceptive practices, such as making false statements about coverage. Agents said they had pre-existing conditions, such as diabetes, and sought coverage. In 8 tests, sales representatives engaged in potentially deceptive practices, such as claiming the pre-existing condition was covered when plan documents said otherwise. We referred these cases to...
      **Released on   Apr 29, 2020**
          Antibiotic Resistance: Additional Federal Actions Needed to Better Determine Magnitude and Reduce Impact
    GAO-20-341
      Published:   Mar 30, 2020
. 
        Publicly Released:   Apr 29, 2020
.
    Antibiotic-resistant infections can be difficult or impossible to treat. We examined federal challenges to addressing antibiotic resistance: Surveillance —Tracking resistant infections is tough because of reliance on sampling and voluntary reporting Diagnostics —Lack of data on clinical outcomes impedes the development and use of antibiotic-resistance tests New treatments —The pipeline of new antibiotics is inadequate and federal efforts haven’t fully incentivized development Antibiotic use —Federal...
    
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