Exhibit 12.1

Computation of Ratio of Earnings to Fixed Charges and Ratio of Earnings to Combined

Fixed Charges
and Preferred Stock Dividend Requirements

(In thousands, except for ratios)

Ratio of Earnings to Fixed Charges



|                                             |  |                         |         |   |      |   |          |      |  |   |         |   |  |      |         |   |  |   |         |  
|-------------------------------------------- |  | ----------------------- | ------- | - | ---- | - | -------- | ---- |  | - | ------- | - |  | ---- | ------- | - |  | - | ------- | -
|                                             |  | Year Ended December 31, |        
|                                             |  | 2008                    |         |   | 2007 |   |          | 2006 |  |   | 2005    |   |  | 2004 |        
|Loss before income taxes                     |  | $                       | (53,170 | ) |      | $ | (125,156 | )    |  | $ | (53,316 | ) |  | $    | (59,011 | ) |  | $ | (93,666 | )
|Add: Fixed charges                           |  |                         | 11,706  |   |      |   | 12,542   |      |  |   | 12,415  |   |  |      | 13,263  |   |  |   | 13,433  |  
|                                             |  |                         |         |   |      |   |          |      |  |   |         |   |  |      |         |   |  |   |         |  
|Earnings, as defined                         |  | $                       | (41,464 | ) |      | $ | (112,614 | )    |  | $ | (40,901 | ) |  | $    | (45,748 | ) |  | $ | (80,233 | )
|                                             |  |                         |         |   |      |   |          |      |  |   |         |   |  |      |         |   |  |   |         |  
|Interest expense                             |  | $                       | 9,923   |   |      | $ | 10,331   |      |  | $ | 10,465  |   |  | $    | 10,679  |   |  | $ | 9,885   |  
|Estimated interest portion of rental expense |  |                         | 1,783   |   |      |   | 2,211    |      |  |   | 1,950   |   |  |      | 2,584   |   |  |   | 3,548   |  
|                                             |  |                         |         |   |      |   |          |      |  |   |         |   |  |      |         |   |  |   |         |  
|Fixed charges                                |  | $                       | 11,706  |   |      | $ | 12,542   |      |  | $ | 12,415  |   |  | $    | 13,263  |   |  | $ | 13,433  |  
|                                             |  |                         |         |   |      |   |          |      |  |   |         |   |  |      |         |   |  |   |         |  
|Deficiency of earnings to fixed charges      |  | $                       | (53,170 | ) |      | $ | (125,156 | )    |  | $ | (53,316 | ) |  | $    | (59,011 | ) |  | $ | (93,666 | )
|                                             |  |                         |         |   |      |   |          |      |  |   |         |   |  |      |         |   |  |   |         |  
|Ratio of earnings to fixed charges           |  |                         | N/A     |   |      |   | N/A      |      |  |   | N/A     |   |  |      | N/A     |   |  |   | N/A     |  

Ratio of Earnings to Combined Fixed Charges and Preferred Stock Dividend Requirements



|                                                                                           |  |                         |         |   |      |   |          |      |  |   |         |   |  |      |         |   |  |   |         |  
|------------------------------------------------------------------------------------------ |  | ----------------------- | ------- | - | ---- | - | -------- | ---- |  | - | ------- | - |  | ---- | ------- | - |  | - | ------- | -
|                                                                                           |  | Year Ended December 31, |        
|                                                                                           |  | 2008                    |         |   | 2007 |   |          | 2006 |  |   | 2005    |   |  | 2004 |        
|Earnings, as defined (from above)                                                          |  | $                       | (41,464 | ) |      | $ | (112,614 | )    |  | $ | (40,901 | ) |  | $    | (45,748 | ) |  | $ | (80,233 | )
|Preferred stock dividend requirements                                                      |  |                         |        |   |      |   |         |      |  |   |        |   |  |      | 4       |   |  |   | 100     |  
|                                                                                           |  |                         |         |   |      |   |          |      |  |   |         |   |  |      |         |   |  |   |         |  
|Earnings, as defined                                                                       |  | $                       | (41,464 | ) |      | $ | (112,614 | )    |  | $ | (40,901 | ) |  | $    | (45,744 | ) |  | $ | (80,133 | )
|                                                                                           |  |                         |         |   |      |   |          |      |  |   |         |   |  |      |         |   |  |   |         |  
|Fixed charges (from above)                                                                 |  | $                       | 11,706  |   |      | $ | 12,542   |      |  | $ | 12,415  |   |  | $    | 13,263  |   |  | $ | 13,433  |  
|Preferred stock dividend requirements                                                      |  |                         |        |   |      |   |         |      |  |   |        |   |  |      | 4       |   |  |   | 100     |  
|                                                                                           |  |                         |         |   |      |   |          |      |  |   |         |   |  |      |         |   |  |   |         |  
|Combined fixed charges and preferred stock dividend requirements                           |  | $                       | 11,706  |   |      | $ | 12,542   |      |  | $ | 12,415  |   |  | $    | 13,267  |   |  | $ | 13,533  |  
|                                                                                           |  |                         |         |   |      |   |          |      |  |   |         |   |  |      |         |   |  |   |         |  
|Deficiency of earnings to combined fixed charges and preferred stock dividend requirements |  | $                       | (53,170 | ) |      | $ | (125,156 | )    |  | $ | (53,316 | ) |  | $    | (59,011 | ) |  | $ | (93,666 | )
|                                                                                           |  |                         |         |   |      |   |          |      |  |   |         |   |  |      |         |   |  |   |         |  
|Ratio of earnings to combined fixed charges and preferred stock dividend requirements      |  |                         | N/A     |   |      |   | N/A      |      |  |   | N/A     |   |  |      | N/A     |   |  |   | N/A     |  

For the purpose of calculating the ratio of earnings to fixed charges, earnings are defined as
consolidated income from continuing operations before income taxes plus fixed charges. Fixed charges are the sum of interest of all indebtedness, including amortization of debt issuance costs, and estimated interest within rental expense. The ratio
of earnings to combined fixed charges and preferred stock dividend requirements includes the tax adjusted deemed dividend to preferred stockholders.