Exhibit 4.3 - Amendment No. 1 to Confidential Private Placement Memorandum



				



Amendment No. 1 to Confidential Private Placement Memorandum 





	     This Amendment No. 1, dated June 15, 2001, to Perma-Fix Environmental Services, Inc.'s
("Perma-Fix" or the "Company") Confidential Private Placement Memorandum, dated April 6, 2001
(the "Memorandum"), amends the Memorandum and Subscription Agreement referenced therein and
attached to the Memorandum as Exhibit "B" ("Subscription Agreement").  All capitalized terms not
defined herein shall have the same meaning as defined in the Memorandum.  This Amendment
amends the Memorandum and Subscription Agreement as follows:




	The maximum number of Units to be offered under the Offering is decreased from 5,000,000
to 4,400,000 Units.  The composition of the Units remains unchanged, with each Unit
consisting of one share of Common Stock and one Warrant to purchase one share of
Common Stock.  The purchase price of one Unit remains $1.75, and the exercise price of
each Warrant remains $1.75.

   	The Maximum Offering amount is reduced from $8,750,000 to $7,700,000.  The Minimum
Offering amount of $2,625,000 and the Use of Proceeds of the Offering remains unchanged.
As a result of the change to the Maximum Offering amount, the sections of the Memorandum
styled "Capitalization" on pages 14 and 15 of the Memorandum is amended as set forth on
Exhibit "A" attached hereto and the Beneficial Ownership table on page 24 of the
Memorandum is amended as set forth on Exhibit "B" attached hereto.

  
	The Warrants and the Warrant Agreement attached as Exhibit "C" to the Memorandum and
referenced in the Subscription Agreement and the warrants issued to each Placement Agent
as a portion of the Placement Agent fees as described in the Memorandum ("Placement
Agent Warrants") shall not be exercisable until the Company has obtained approval of its
shareholders entitled to vote pursuant to the Act and Rule 4350 of the Nasdaq rules to issue
the shares of Common Stock issuable upon exercise of the Warrants and the Placement
Agent Warrants.  The exercise price under each Warrant and the Placement Agent Warrants
shall remain $1.75 per share.  The Company will solicit for such shareholder approval as
soon as possible following the final Closing of the Offering.  A copy of the revised Warrant
Agreement is attached hereto as Exhibit "C", and the Warrant Agreement attached hereto as
Exhibit "C" replaces, in all respects, the original Warrant Agreement attached to the
Memorandum as Exhibit "C".  Originally, the Warrant and the Warrant Agreement provided
that the Warrant may be exercised at any time commencing on the Issue Date.   The revised
Warrant Agreement attached hereto as Exhibit "C" provides that the Warrant is not
exercisable until the Company has received shareholder approval to issue the shares of
Common Stock issuable upon exercise of the Warrants.  The Warrants shall remain
exercisable at any time after such shareholder approval is obtained until the fifth anniversary
of the Issue Date.



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  	The Company will file within 60 days following the final Closing a Registration Statement
on Form S-3, or such other suitable registration statement acceptable to the Company with
the SEC to register under the Act the Common Stock included in the Units sold and the
Common Stock issuable upon exercise of the Warrants (the "Registration Statement"). This
changes the requirement in the Memorandum and the Subscription Agreement for the
Company to use its reasonable efforts to file the Registration Statement within 150 days
following the final Closing.  In addition, if the Company does not file such Registration
Statement within 60 days from the final Closing,  the Company agrees to pay, in the form
of liquidated damages, to each Subscriber that has purchased Units under the Offering a
monthly amount equal to 1% of the amount such Subscriber paid the Company for the Units
the Subscriber purchased from the Company pursuant to the Offering for each full month
after such 60 day period that such Registration Statement has not been filed with the SEC
 .

   	In addition to the "Risk Factors" set forth on pages 6 through 13 of the Memorandum, the
following two additional "Risk Factors" are added at the end thereof:





		                     "Inability to obtain Shareholder Approval.  If the Company is unable
to 

                      obtain shareholder approval to issue the shares of Common Stock 

                      issuable upon exercise of the Warrants, the Subscriber shall not be
able 

                      to exercise the Warrants and will not receive any Common Stock
under 

                      the Warrants. 


		                     Payment of Liquidated Damages.  If the Company is unable to file the 

                     Registration Statement with the SEC within 60 days following the
final 

                     Closing and such inability continues for an extended period of
time thereafter, 

                     the Company's obligation to pay such liquidated
damages may have a 

                     material adverse effect on the liquidity and
financial condition of the Company."


	All other terms and conditions contained in the Memorandum and Subscription Agreement 

remain unchanged.