### 1 

# Supplemental Information on **E**

**- FAST CEM Outputs (Clear**  **Protective Coating Spray)**

FIRST IS A DESCRIPTION OF THE ASSUMPTIONS, THEN THE MODEL OUTPUT FOLLOWS

(NOTE THAT FULL CITATIONS FOR ALL REFERENCES CITED CAN BE FOUND IN THE REFERENCE

SECTION OF THE RISK ASSESSMENT)

Exposure Scenario for Clear protective coating spray

1. Description of product from manufacturer’s product technical data sheet and 17

- Jan

2012 Material Safety Data Sheet ( s ee supplemental document titled “Supplemental Product Information for t he TSCA Workplan Chemical Risk Assessment of TCE (External Review Draft).pdf” for more details ):

• Clear acrylic protective coating for use by artists, printers, picture framers, and screen printers.

• Protects artwork, proofs, photos, blueprints, etc. from a ging, yellowing

, or smudging.

• Safe to use on watercolor, pastel, charcoal, pencil, and colored ink renderings.

• Provides a clear acrylic protective coating that stays clear under any condition. Prevents dog

- earing and color fading of art and papers from co nstant handling and it keeps artwork from fading, due to exposure to light. Ideal as ink jet laminate.

• Artwork: Protects finished watercolor, pastel, charcoal, pencil, and colored ink renderings.

• Photography: Protects surfaces, improves contrast.

• Crafts : Adds luster to ceramics, preserves models.

• Valuable papers: Protects books, blueprints, maps, charts, documents, records, and carbon copies.

2. Assumptions for E

- FAST/CEM model runs:

• Begin with the E

- FAST/CEM default assumptions for Aerosol Paint, and adjust the assumptions for frequency of use, exposure duration (chronic), mass of product per event, and duration of event to represent hobbyist use of clear protective coating

spray . Re tain other assumptions for “Product Sprayed on Surface

– Constant Rate
and Incremental Models”: assume that one percent of the sprayed product is aerosolized and therefore immediately available for uptake by inhalation; assume that the remainder of the pr oduct contacts the target surface, and subsequently volatilizes at a rate that depends upon the chemical’s molecular weight and vapor pressure. [The aerosolized portion is treated using a constant emission rate model. The remaining (non

- aerosolized) mass is treated by combining a constant

### 2 

### application rate with an exponentially declining rate for each instantaneously applied segment.]

• User is an avid hobbyist who uses the clear protective coating spray indoors, at home, once a week (52 events per year) to protect artwork, crafts, etc.

• Hobbyist uses two cans of clear protective coating spray per year. Hobbyist
therefore uses 21 ounces of clear protective coating spray per year, 21/52 = 0.40

ounces clear protective coating spray per use, 0.40 ounces x 28.349523 g/ ounce = 11 g clear protective coating spray /use.

• An actual formulation of clear protective coating spray contains 20 to 30 percent
TCE. For E

- FAST/CEM, assume a weight fraction of 0.3.

• The hobbyist is an adult who uses the clear protective coating spray for 57 years as an adult (ages 21 to 78) or the hobbyist is a teenager or young adult who uses the clear protective coating spray for 5 years (ages 16 to 20).

• Non

- user residents of the home can be of any age.

• The E

- FAST/CEM runs estimate the active exposure of the user (hobbyist) and the passive exposure of non

- users living in a home where the clear protective coating

spray is used. Age groups are: less than age 1; ages 1 to 2; ages 3 to 5; ages 6 to 10; ages 11 to 15; ages 16 to 20; and age s 21 to 78.

• E

- FAST/CEM scenarios for children do not permit them to be present in the room of use during product use. Estimated exposures therefore represent their passive exposures while they are elsewhere in the home.

• Duration of event is 0.5 h ou r.

• Mole cular weight of TCE is 131.39.

• Vapor pressure of TCE is 73.46 torr at 25 ° C.

• For further information on the E

- FAST/CEM defaults or underlying equations, see
the E

- FAST documentation manual ( US EPA, 2007a )

• Exposure factors for age bins, inhalation rates, body weights, and life expectancy are derived from the 2011 Exposure Factors Handbook ( US EPA, 2011d ) and replace
the E

- FAST defaults derived from the 1997 Exposure Factors Handbook ( US EPA,

1997 )

.

• NOTE: the E

- FAST/CEM exposure estimates are potential dose rate s that do not include any assumptions about absorption through the lung.



# -------------------------------------------------------------------

### 3 

# E

- FAST/CEM Input and Output Summaries for Clear protective coating spray

CEM Inputs ID Number: 1 fixa tive user 21

- 78
Product: clear protective coating spray Chemical Name: TCE

Scenario: User Defined Population: ages 21

- 78 Molecular Weight (g/mole): 131.4 Vapor Pressure (torr): 73.46 Consumer Product Weight Fraction

- Central Tendency (unitless): 0.3 Consumer Product Weight Fraction

- High

- End (unitless): 0.3

Inhalation Inputs Frequency of Use (chronic) (events/yr): 52 Exposure Duration (chronic) (years): 57

Frequency of Use (acute) (events/day): 1 Exposure Duration (acute) (days): 1

Mass of Product Used per Event

- Central Tendency (g): 11 Mass of Product Used per Event

- High

- End (g): 11

Inhalation Rate During Use (m 3 /hr): 0.74 Duration of Event

- Central Tendency (hours/event): 0.5

Inhalation Rate After Use (m 3 /hr): 0.611 Duration of Event

- High

- End (hours/event): 0.5

Zone 1 Volume (m 3 ): 20 Whole House Volume (m 3 ): 369 Air Exchange Rate (air exchanges/hr): 0.45 Body Weight (kg): 80

Portion of Aerosol in Air (unitless): 0.01 Activity Patterns

User: 1 1 1 1 1 1 1 2 3 5 5 4 2 4 7 7 4 2 2 7 4 4 4 1

Non

- User: 1 1 1 1 1 1 1 1 3 2 4 4 2 4 7 7 4 2 2 7 4 4 4 1

Hour: 0 6 12 18

Start Time: 9 Room of Use: 5. Utility Room Dermal Inputs There are no Dermal inputs for this scenario. Averaging Time (chronic) (days): 2.85e+

04 Averaging time (acute) (days) : 1

Activity Patterns: 1 Bedroom; 2 Kitchen; 3 Bathroom; 4 Living Room; 5 Utility Room; 6 Car; 7 Out (outside the house)

### 4 CEM Inhalation Exposure Estimates

ID Number: 1 fixative user 21

- 78
Scenario: User Defined Population: ages 21

- 78 Exposure Duration (years) chronic: 57 Exposure Duration (days) acute: 1

Exposure Units Result AT (days)

Chronic Cancer

LADD pot (mg/kg

- day) 4.68e

- 02 2.85e+04

LADC pot (mg/m 3 ) 2.21e

- 01 2.85e+04

Acute

ADR pot (mg/kg

- day) 4.50e

- 01 1 Cp pot (mg/m 3 ) 6.70e+01 NA

LADD

- Lifetime Average Daily Dose (mg/kg

- day) LADC

- Lifetime Average Daily Concentration (mg/m 3 )

ADR

- Acute Dose Rate (mg/kg

- day) Cp

- Peak Concentration (mg/m 3 )

Note: 78 years = 2.85e+04 days ; pot

- potential dose Note: The potential peak concentration (Cp pot ) is defined as the highest instantaneous air concentration that is calculated by the model during any 10

- second time step, and should not be interpreted as a daily maximum

concentration. Note: The general Agency guidance for assessing short

- term, infrequent events (for most chemicals, an exposure of less than 24 hours that occurs no more frequently than monthly) is to treat such events as independent, acute exposures rather than as chronic exposure ( US EPA, 1998a )

.

### 5 CEM Inputs ID Number: 2 fixative non

- user 21

- 78
Product: clear protective coating spray Chemical Name: TCE

Scenario: User Defined Population: ages 21

- 78 Molecular Weight (g/mole): 131.4 Vapor Pressure (torr): 73.46 Consumer Product Weight Fraction

- Central Tendency (unitless): 0.3 Consumer Product Weight Fraction

- High

- End (unitless): 0.3

Inhalation Inputs Frequency of Use (chronic) (events/yr): 52 Exposure Duration (chronic) (years): 57

Frequency of Use (acute) (events/day): 1 Exposure Duration (acute) (days): 1

Mass of Product Used per Event

- Central Tendency (g): 11 Mass of Product Used per Event

- High

- End (g): 11

Inhalation Rate During Use (m 3 /hr): 0.611 Duration of Event

- Central Tendency (hours/event): 0.5

Inhalation Rate After Use (m 3 /hr): 0.611 Duration of Event

- High

- End (hours/event): 0.5

Zone 1 Volume (m 3 ): 20 Whole House Volume (m 3 ): 369 Air Exchange Rate (air exchanges/hr): 0.45 Body Weight (kg): 80

Portion of Aerosol in Air (unitless): 0.01 Activity Patterns

User: 1 1 1 1 1 1 1 1 3 2 4 4 2 4 7 7 4 2 2 7 4 4 4 1

Non

- User: 1 1 1 1 1 1 1 1 3 2 4 4 2 4 7 7 4 2 2 7 4 4 4 1

Hour: 0 6 12 18

Start Time: 9 Room of Use: 5. Utility Room Dermal Inputs There are no Dermal inputs for this scenario. Averaging Time (chronic) (days): 2.85e+

04 Averaging time (acute) (days) : 1

Activity Patterns: 1 Bedroom; 2 Kitchen; 3 Bathroom; 4 Living Room; 5 Utility Room; 6 Car; 7 Out (outside the house)

### 6 CEM Inhalation Exposure Estimates

ID Number: 2 fixative non

- user 21

- 78
Scenario: User Defined Population: ages 21

- 78 Exposure Duration (years) chronic: 57 Exposure Duration (days) acute: 1

Exposure Units Result AT (days)

Chronic Cancer

LADD pot (mg/kg

- day) 1.31e

- 02 2.85e+04

LADC pot (mg/m 3 ) 7.16e

- 02 2.85e+04

Acute

ADR pot (mg/kg

- day) 1.26e

- 01 1 Cp pot (mg/m 3 ) 6.20e+00 NA

LADD

- Lifetime Average Daily Dose (mg/kg

- day) LADC

- Lifetime Average Daily Concentration (mg/m 3 )

ADR

- Acute Dose Rate (mg/kg

- day) Cp

- Peak Concentration (mg/m 3 )

Note: 78 years = 2.85e+04 days ; pot

- potential dose Note: The potential peak concentration (Cp pot ) is defined as the highest instantaneous air concentration that is calculated by the model during any 10

- second time step, and should not be interpreted as a daily maximum

concentration. Note: The general Agency guidance for assessing short

- term, infrequent events (for most chemicals, an exposure of less than 24 hours that occurs no more frequently than monthly) is to treat such events as independent, acute exposures rather than as chronic exposure ( US EPA, 1998a )

.

### 7 CEM Inputs ID Number: 3 fixative use r 16

- 20
Product: clear protective coating spray Chemical Name: TCE

Scenario: User Defined Population: ages 16

- 20 Molecular Weight (g/mole): 131.4 Vapor Pressure (torr): 73.46 Consumer Product Weight Fraction

- Central Tendency (unitless): 0.3 Consumer Product Weight Fraction

- High

- End (unitless): 0.3

Inhalation Inputs Frequency of Use (chronic) (events/yr): 52 Exposure Duration (chronic) (years): 5

Frequency of Use (acute) (events/day): 1 Exposure Duration (acute) (days): 1

Mass of Product Used per Event

- Central Tendency (g): 11 Mass of Product Used per Event

- High

- End (g): 11

Inhalation Rate During Use (m 3 /hr): 0.72 Duration of Event

- Central Tendency (hours/event): 0.5

Inhalation Rate After Use (m 3 /hr): 0.679 Duration of Event

- High

- End (hours/event): 0.5

Zone 1 Volume (m 3 ): 20 Whole House Volume (m 3 ): 369 Air Exchange Rate (air exchanges/hr): 0.45 Body Weight (kg): 71.6

Portion of Aerosol in Air (unitless): 0.01 Activity Patterns

User: 1 1 1 1 1 1 1 2 3 5 5 4 2 4 7 7 4 2 2 7 4 4 4 1

Non

- User: 1 1 1 1 1 1 1 1 3 2 4 4 2 4 7 7 4 2 2 7 4 4 4 1

Hour: 0 6 12 18

Start Time: 9 Room of Use: 5. Utility Room Dermal Inputs There are no Dermal inputs for this scenario. Averaging Time (chronic) (days): 2.85e+

04 Averaging time (acute) (days) : 1

Activity Patterns: 1 Bedroom; 2 Kitchen; 3 Bathroom; 4 Living Room; 5 Utility Room; 6 Car; 7 Out (outside the house)

### 8 CEM Inhalation Exposure Estimates

ID Number: 3 fixative user 16

- 20
Scenario: User Defined Population: ages 16

- 20 Exposure Duration (years) chronic: 5 Exposure Duration (days) acute: 1

Exposure Units Result AT (days)

Chronic Cancer

LADD pot (mg/kg

- day) 4.62e

- 03 2.85e+04

LADC pot (mg/m 3 ) 1.94e

- 02 2.85e+04

Acute

ADR pot (mg/kg

- day) 5.06e

- 01 1 Cp pot (mg/m 3 ) 6.70e+01 NA

LADD

- Lifetime Average Daily Dose (mg/kg

- day) LADC

- Lifetime Average Daily Concentration (mg/m 3 )

ADR

- Acute Dose Rate (mg/kg

- day) Cp

- Peak Concentration (mg/m 3 )

Note: 78 years = 2.85e+04 days ; pot

- potential dose Note: The potential peak concentration (Cp pot ) is defined as the highest instantaneous air concentration that is calculated by the model during any 10

- second time step, and should not be interpreted as a daily maximum

concentration. Note: The general Agency guidance for assessing short

- term, infrequent events (for most chemicals, an exposure of less than 24 hours that occurs no more frequently than monthly) is to treat such events as independent, acute exposures rather than as chronic exposure ( US EPA, 1998a )

.

### 9 CEM Inputs ID Number: 4 fixative no n

- user 16

- 20
Product: clear protective coating spray Chemical Name: TCE

Scenario: User Defined Population: ages 16

- 20 Molecular Weight (g/mole): 131.4 Vapor Pressure (torr): 73.46 Consumer Product Weight Fraction

- Central Tendency (unitless): 0.3 Consumer Product Weight Fraction

- High

- End (unitless): 0.3

Inhalation Inputs Frequency of Use (chronic) (events/yr): 52 Exposure Duration (chronic) (years): 5

Frequency of Use (acute) (events/day): 1 Exposure Duration (acute) (days): 1

Mass of Product Used per Event

- Central Tendency (g): 11 Mass of Product Used per Event

- High

- End (g): 11

Inhalation Rate During Use (m 3 /hr): 0.679 Duration of Event

- Central Tendency (hours/event): 0.5

Inhalation Rate After Use (m 3 /hr): 0.679 Duration of Event

- High

- End (hours/event): 0.5

Zone 1 Volume (m 3 ): 20 Whole House Volume (m 3 ): 369 Air Exchange Rate (air exchanges/hr): 0.45 Body Weight (kg): 71.6

Portion of Aerosol in Air (unitless): 0.01 Activity Patterns

User: 1 1 1 1 1 1 1 1 3 2 4 4 2 4 7 7 4 2 2 7 4 4 4 1

Non

- User: 1 1 1 1 1 1 1 1 3 2 4 4 2 4 7 7 4 2 2 7 4 4 4 1

Hour: 0 6 12 18

Start Time: 9 Room of Use: 5. Utility Room Dermal Inputs There are no Dermal inputs for this scenario. Averaging Time (chronic) (days): 2.85e+

04 Averaging time (acute) (days) : 1

Activity Patterns: 1 Bedroom; 2 Kitchen; 3 Bathroom; 4 Living Room; 5 Utility Room; 6 Car; 7 Out (outside the house)

### 10 CEM Inhalation Exposure Estimates

ID Number: 4 fixative non

- user 16

- 20
Scenario: User Defined Population: ages 16

- 20 Exposure Duration (years) chronic: 5 Exposure Duration (days) acute: 1

Exposure Units Result AT (days)

Chronic Cancer

LADD pot (mg/kg

- day) 1.43e

- 03 2.85e+04

LADC pot (mg/m 3 ) 6.28e

- 03 2.85e+04

Acute

ADR pot (mg/kg

- day) 1.57e

- 01 1 Cp pot (mg/m 3 ) 6.20e+00 NA

LADD

- Lifetime Average Daily Dose (mg/kg

- day) LADC

- Lifetime Average Daily Concentration (mg/m 3 )

ADR

- Acute Dose Rate (mg/kg

- day) Cp

- Peak Concentration (mg/m 3 )

Note: 78 years = 2.85e+04 days ; pot

- potential dose Note: The potential peak concentration (Cp pot ) is defined as the highest instantaneous air concentration that is calculated by the model during any 10

- second time step, and should not be interpreted as a daily maximum

concentration. Note: The general Agency guidance for assessing short

- term, infrequent events (for most chemicals, an exposure of less than 24 hours that occurs no more frequently than monthly) is to treat such events as independent, acute exposures rather than as chronic exposure ( US EPA, 1998a )

.

### 11 CEM Inputs ID Number: 5 fixative non

- user 11

- 15
Product: clear protective coating spray Chemical Name: TCE

Scenario: User Defined Population: ages 11

- 15 Molecular Weight (g/mole): 131.4 Vapor Pressure (torr): 73.46 Consumer Product Weight Fraction

- Central Tendency (unitless): 0.3 Consumer Product Weight Fraction

- High

- End (unitless): 0.3

Inhalation Inputs Frequency of Use (chronic) (events/yr): 52 Exposure Duration (chronic) (years): 5

Frequency of Use (acute) (events/day): 1 Exposure Duration (acute) (days): 1

Mass of Product Used per Event

- Central Tendency (g): 11 Mass of Product Used per Event

- High

- End (g): 11

Inhalation Rate During Use (m 3 /hr): 0.633 Duration of Event

- Central Tendency (hours/event): 0.5

Inhalation Rate After Use (m 3 /hr): 0.633 Duration of Event

- High

- End (hours/event): 0.5

Zone 1 Volume (m 3 ): 20 Whole House Volume (m 3 ): 369 Air Exchange Rate (air exchanges/hr): 0.45 Body Weight (kg): 56.8

Portion of Aerosol in Air (unitless): 0.01 Activity Patterns

User: 1 1 1 1 1 1 1 1 3 2 4 4 2 4 7 7 4 2 2 7 4 4 4 1

Non

- User: 1 1 1 1 1 1 1 1 3 2 4 4 2 4 7 7 4 2 2 7 4 4 4 1

Hour: 0 6 12 18

Start Time: 9 Room of Use: 5. Utility Room Dermal Inputs There are no Dermal inputs for this scenario. Averaging Time (chronic) (days): 2.85e+

04 Averaging time (acute) (days) : 1

Activity Patterns: 1 Bedroom; 2 Kitchen; 3 Bathroom; 4 Living Room; 5 Utility Room; 6 Car; 7 Out (outside the house)

### 12 CEM Inhalation Exposure Estimates

ID Number: 5 fixative non

- user 11

- 15

Scenario: User Defined Population: ages 11

- 15
Exposure Duration (years) chronic: 5 Exposure Duration (days) acute: 1

Exposure Units Result AT (days)

Chronic Cancer

LADD pot (mg/kg

- day) 1.68e

- 03 2.85e+04

LADC pot (mg/m 3 ) 6.28e

- 03 2.85e+04

Acute

ADR pot (mg/kg

- day) 1.84e

- 01 1

Cp pot (mg/m 3 ) 6.20e+0

0 NA

LADD

- Lifetime Average Daily Dose (mg/kg

- day) LADC

- Lifetime Average Daily Concentration (mg/m 3 )

ADR

- Acute Dose Rate (mg/kg

- day) Cp

- Peak Concentration (mg/m 3 )

Note: 78 years = 2.85e+04 days ; pot

- potential dose Note: The potential peak concentration (Cp pot ) is defined as the highest instantaneous air concentration that is calculated by the model during any 10

- second time step, and should not be interpreted as a daily maximum

concentration. Note: The general Agency guidance for assessing short

- term, infrequent events (for most chemicals, an exposure of less than 24 hours that occurs no more frequently than monthly) is to treat such events as independent, acute exposures rather than as chronic exposure ( US EPA, 1998a )

.

### 13 CEM Inputs ID Number: 6 fixative non

- user 6

- 10
Product: clear protective coating spray Chemical Name: TCE

Scenario: User Defined Population: ages 6

- 10 Molecular Weight (g/mole): 131.4 Vapor Pressure (torr): 73.46 Consumer Product Weight Fraction

- Central Tendency (unitless): 0.3 Consumer Product Weight Fraction

- High

- End (unitless): 0.3

Inhalation Inputs Frequency of Use (chronic) (events/yr): 52 Exposure Duration (chronic) (years): 5

Frequency of Use (acute) (events/day): 1 Exposure Duration (acute) (days): 1

Mass of Product Used per Event

- Central Tendency (g): 11 Mass of Product Used per Event

- High

- End (g): 11

Inhalation Rate During Use (m 3 /hr): 0.5 Duration of Event

- Central Tendency (hours/event): 0.5

Inhalation Rate After Use (m 3 /hr): 0.5 Duration of Event

- High

- End (hours/event): 0.5

Zone 1 Volume (m 3 ): 20 Whole House Volume (m 3 ): 369 Air Exchange Rate (air exchanges/hr): 0.45 Body Weight (kg): 31.8

Portion of Aerosol in Air (unitless): 0.01 Activity Patterns

User: 1 1 1 1 1 1 1 1 3 2 4 4 2 4 7 7 4 2 2 7 4 4 4 1

Non

- User: 1 1 1 1 1 1 1 1 3 2 4 4 2 4 7 7 4 2 2 7 4 4 4 1

Hour: 0 6 12 18

Start Time: 9 Room of Use: 5. Utility Room Dermal Inputs There are no Dermal inputs for this scenario. Averaging Time (chronic) (days): 2.85e+

04 Averaging time (acute) (days) : 1

Activity Patterns: 1 Bedroom; 2 Kitchen; 3 Bathroom; 4 Living Room; 5 Utility Room; 6 Car; 7 Out (outside the house)

### 14 CEM Inhalation Exposure Estimates

ID Number: 6 fixative non

- user 6

- 10
Scenario: User Defined Population: ages 6

- 10 Exposure Duration (years) chronic: 5 Exposure Duration (days) acute: 1

Exposure Units Result AT (days)

Chronic Cancer

LADD pot (mg/kg

- day) 2.37e

- 03 2.85e+04

LADC pot (mg/m 3 ) 6.28e

- 03 2.85e+04

Acute

ADR pot (mg/kg

- day) 2.60e

- 01 1 Cp pot (mg/m 3 ) 6.20e+00 NA

LADD

- Lifetime Average Daily Dose (mg/kg

- day) LADC

- Lifetime Average Daily Concentration (mg/m 3 )

ADR

- Acute Dose Rate (mg/kg

- day) Cp

- Peak Concentration (mg/m 3 )

Note: 78 years = 2.85e+04 days ; pot

- potential dose Note: The potential peak concentration (Cp pot ) is defined as the highest instantaneous air concentration that is calculated by the model during any 10

- second time step, and should not be interpreted as a daily maximum

concentration. Note: The general Agency guidance for assessing short

- term, infrequent events (for most chemicals, an exposure of less than 24 hours that occurs no more frequently than monthly) is to treat such events as independent, acute exposures rather than as chronic exposure ( US EPA, 1998a )

.

### 15 CEM Inputs ID Number: 7 fixative non

- user 3

- 5
Product: clear protective coating spray Chemical Name: TCE

Scenario: User Defined Population: ages 3

- 5 Molecular Weight (g/mole): 131.4 Vapor Pressure (torr): 73.46 Consumer Product Weight Fraction

- Central Tendency (unitless): 0.3 Consumer Product Weight Fraction

- High

- End (unitless): 0.3

Inhalation Inputs Frequency of Use (chronic) (events/yr): 52 Exposure Duration (chronic) (years): 3

Frequency of Use (acute) (events/day): 1 Exposure Duration (acute) (days): 1

Mass of Product Used per Event

- Central Tendency (g): 11 Mass of Product Used per Event

- High

- End (g): 11

Inhalation Rate During Use (m 3 /hr): 0.421 Duration of Event

- Central Tendency (hours/event): 0.5

Inhalation Rate After Use (m 3 /hr): 0.421 Duration of Event

- High

- End (hours/event): 0.5

Zone 1 Volume (m 3 ): 20 Whole House Volume (m 3 ): 369 Air Exchange Rate (air exchanges/hr): 0.45 Body Weight (kg): 18.6

Portion of Aerosol in Air (unitless): 0.01 Activity Patterns

User: 1 1 1 1 1 1 1 1 3 2 4 4 2 4 7 7 4 2 2 7 4 4 4 1

Non

- User: 1 1 1 1 1 1 1 1 3 2 4 4 2 4 7 7 4 2 2 7 4 4 4 1

Hour: 0 6 12 18

Start Time: 9 Room of Use: 5. Utility Room Dermal Inputs There are no Dermal inputs for this scenario. Averaging Time (chronic) (days): 2.85e+

04 Averaging time (acute) (days) : 1

Activity Patterns: 1 Bedroom; 2 Kitchen; 3 Bathroom; 4 Living Room; 5 Utility Room; 6 Car; 7 Out (outside the house)

### 16 CEM Inhalation Exposure Estimates

ID Number: 7 fixative non

- user 3

- 5
Scenario: User Defined Population: ages 3

- 5 Exposure Duration (years) chronic: 3 Exposure Duration (days) acute: 1

Exposure Units Result AT (days)

Chronic Cancer

LADD pot (mg/kg

- day) 2.05e

- 03 2.85e+04

LADC pot (mg/m 3 ) 3.77e

- 03 2.85e+04

Acute

ADR pot (mg/kg

- day) 3.74e

- 01 1 Cp pot (mg/m 3 ) 6.20e+00 NA

LADD

- Lifetime Average Daily Dose (mg/kg

- day) LADC

- Lifetime Average Daily Concentration (mg/m 3 )

ADR

- Acute Dose Rate (mg/kg

- day) Cp

- Peak Concentration (mg/m 3 )

Note: 78 years = 2.85e+04 days ; pot

- potential dose Note: The potential peak concentration (Cp pot ) is defined as the highest instantaneous air concentration that is calculated by the model during any 10

- second time step, and should not be interpreted as a daily maximum

concentration. Note: The general Agency guidance for assessing short

- term, infrequent events (for most chemicals, an exposure of less than 24 hours that occurs no more frequently than monthly) is to treat such events as independent, acute exposures rather than as chronic exposure ( US EPA, 1998a )

.

### 17 CEM Inputs ID Number: 8 fixative non

- user 1

- 2
Product: clear protective coating spray Chemical Name: TCE

Scenario: User Defined Population: ages 1

- 2 Molecular Weight (g/mole): 131.4 Vapor Pressure (torr): 73.46 Consumer Product Weight Fraction

- Central Tendency (unitless): 0.3 Consumer Product Weight Fraction

- High

- End (unitless): 0.3

Inhalation Inputs Frequency of Use (chronic) (events/yr): 52 Exposure Duration (chronic) (years): 2

Frequency of Use (acute) (events/day): 1 Exposure Duration (acute) (days): 1

Mass of Product Used per Event

- Central Tendency (g): 11 Mass of Product Used per Event

- High

- End (g): 11

Inhalation Rate During Use (m 3 /hr): 0.35 Duration of Event

- Central Tendency (hours/event): 0.5

Inhalation Rate After Use (m 3 /hr): 0.35 Duration of Event

- High

- End (hours/event): 0.5

Zone 1 Volume (m 3 ): 20 Whole House Volume (m 3 ): 369 Air Exchange Rate (air exchanges/hr): 0.45 Body Weight (kg): 12.6

Portion of Aerosol in Air (unitless): 0.01 Activity Patterns

User: 1 1 1 1 1 1 1 1 3 2 4 4 2 4 7 7 4 2 2 7 4 4 4 1

Non

- User: 1 1 1 1 1 1 1 1 3 2 4 4 2 4 7 7 4 2 2 7 4 4 4 1

Hour: 0 6 12 18

Start Time: 9 Room of Use: 5. Utility Room Dermal Inputs There are no Dermal inputs for this scenario. Averaging Time (chronic) (days): 2.85e+

04 Averaging time (acute) (days) : 1

Activity Patterns: 1 Bedroom; 2 Kitchen; 3 Bathroom; 4 Living Room; 5 Utility Room; 6 Car; 7 Out (outside the house)

### 18 CEM Inhalation Exposure Estimates

ID Number: 8 fixative non

- user 1

- 2
Scenario: User Defined Population: ages 1

- 2 Exposure Duration (years) chronic: 2 Exposure Duration (days) acute: 1

Exposure Units Result AT (days)

Chronic Cancer

LADD pot (mg/kg

- day) 1.67e

- 03 2.85e+04

LADC pot (mg/m 3 ) 2.51e

- 03 2.85e+04

Acute

ADR pot (mg/kg

- day) 4.59e

- 01 1 Cp pot (mg/m 3 ) 6.20e+00 NA

LADD

- Lifetime Average Daily Dose (mg/kg

- day) LADC

- Lifetime Average Daily Concentration (mg/m 3 )

ADR

- Acute Dose Rate (mg/kg

- day) Cp

- Peak Concentration (mg/m 3 )

Note: 78 years = 2.85e+04 days ; pot

- potential dose Note: The potential peak concentration (Cp pot ) is defined as the highest instantaneous air concentration that is calculated by the model during any 10

- second time step, and should not be interpreted as a daily maximum

concentration. Note: The general Agency guidance for assessing short

- term, infrequent events (for most chemicals, an exposure of less than 24 hours that occurs no more frequently than monthly) is to treat such events as independent, acute exposures rather than as chronic exposure ( US EPA, 1998a )

.

### 19 CEM Inputs ID Number: 9 fix ative non

- user age <1
Product: clear protective coating spray Chemical Name: TCE

Scenario: User Defined Population: age <1 Molecular Weight (g/mole): 131.4 Vapor Pressure (torr): 73.46 Consumer Product Weight Fraction

- Central Tendency (unitless): 0.3 Consumer Product Weight Fraction

- High

- End (unitless): 0.3

Inhalation Inputs Frequency of Use (chronic) (events/yr): 52 Exposure Duration (chronic) (years): 1

Frequency of Use (acute) (events/day): 1 Exposure Duration (acute) (days): 1

Mass of Product Used per Event

- Central Tendency (g): 11 Mass of Product Used per Event

- High

- End (g): 11

Inhalation Rate During Use (m 3 /hr): 0.23 Duration of Event

- Central Tendency (hours/event): 0.5

Inhalation Rate After Use (m 3 /hr): 0.23 Duration of Event

- High

- End (hours/event): 0.5

Zone 1 Volume (m 3 ): 20 Whole House Volume (m 3 ): 369 Air Exchange Rate (air exchanges/hr): 0.45 Body Weight (kg): 7.8

Portion of Aerosol in Air (unitless): 0.01 Activity Patterns

User: 1 1 1 1 1 1 1 1 3 2 4 4 2 4 7 7 4 2 2 7 4 4 4 1

Non

- User: 1 1 1 1 1 1 1 1 3 2 4 4 2 4 7 7 4 2 2 7 4 4 4 1

Hour: 0 6 12 18

Start Time: 9 Room of Use: 5. Utility Room Dermal Inputs There are no Dermal inputs for this scenario. Averaging Time (chronic) (days): 2.85e+

04 Averaging time (acute) (days) : 1

Activity Patterns: 1 Bedroom; 2 Kitchen; 3 Bathroom; 4 Living Room; 5 Utility Room; 6 Car; 7 Out (outside the house)

### 20 CEM Inhalation Exposure Estimates

ID Number: 9 fixative non

- user age <1
Scenario: User Defined Population: age <1 Exposure Duration (years) chronic: 1 Exposure Duration (days) acute: 1

Exposure Units Result AT (days)

Chronic Cancer

LADD pot (mg/kg

- day) 8.89e

- 04 2.85e+04

LADC pot (mg/m 3 ) 1.26e

- 03 2.85e+04

Acute

ADR pot (mg/kg

- day) 4.86e

- 01 1 Cp pot (mg/m 3 ) 6.20e+00 NA

LADD

- Lifetime Average Daily Dose (mg/kg

day) LADC

- Lifetime Average Daily Concentration (mg/m 3 )

ADR

- Acute Dose Rate (mg/kg

- day) Cp

- Peak Concentration (mg/m 3 )

Note: 78 years = 2.85e+04 days ; pot

- potential dose Note: The potential peak concentration (Cp pot ) is defined as the highest instantaneous air concentration that is calculated by the model during any 10

- second time step, and should not be interpreted as a daily maximum

concentration. Note: The general Agency guidance for assessing short

- term, infrequent events (for most chemicals, an exposure of less than 24 hours that occurs no more frequently than monthly) is to treat such events as independent, acute exposures rather than as chronic exposure ( US EPA, 1998a )

.

### 21 Exposure Parameter Values Used in E

- FAST/CEM for TCE Modeling

. Exposure

Parameter Population Exposure Type Default
Value Source Comment

Body Weight (BW) Adult (≥21 years) All 80.0 kg US EP A (2011d ) Table 8

- 3 (page 8

- 12): Average of mean body weights for all adults (≥21 years),
male and female combined. Based on US

EPA a nalysis of NHANES 1999

- 2006 data

. Youth (16

- 20 years) All 71.6 kg US EPA (2011d ) Table 8

- 1 (page 8

- 2): Mean body weight for age class 16

- <21 years. See Table 8

- 3 (page 8

- 12) for sample sizes. Based on US EPA analysis of NHANES 1999

- 2006 data.
Youth (11

- 15 years) All 56.8 kg US EPA (2011d ) Table 8

- 1 (page 8

- 2): Mean body weight for age class 11

- <16 years. See Table 8

- 3 (page 8

- 12) for sa mple sizes. Based on US EPA analysis of NHANES 1999

- 2006 data.
Child (6

- 10 years) All 31.8 kg US EPA (2011d ) Table 8

- 1 (page 8

- 2): Me an body weight for age class 6

- <11 years. See Table 8

- 3 (page 8

- 12) for sample sizes. Based on US EPA analysis of NHANES 1999

- 2006 data.
Small child (3

- 5 years) All 18.6 kg US EPA (2011d ) Table 8

- 1 (page 8

- 2): Mean body weight for age class 3

- <6 years. See Table 8

- 3 (page 8

- 12) for sample sizes. Based on US EPA analysis of NHANES 1999

- 2006 data.
Infant (1

- 2 years) All 12.6 kg US EPA (2011d ) Table 8

- 1 (page 8

- 2): Average of mean body weights for age classes 1

- <2 and 2

- <3 years. See Table 8

- 3 (page 8

- 12) for sample sizes. Based on US EPA analysis of

NHANES 1999

- 2006 data.
Infant (<1 year) All 7.8 kg US EPA (2011d ) Table 8

- 1 (page 8

- 2): Weighted average of mean body weights for age classes 0

- <1, 1

- <3, 3

- <6, and 6

- <12 months. See Table 8

- 3 (page 8

- 12) for sample sizes. Based on US EPA analysis of NHANES 1999

- 2006 data.

### 22 Exposure Parameter Values Used in E

- FAST/CEM for TCE Modeling.

Exposure

Parameter Population Exposure Type Default
Value Source Comment

Inhalation

Rate (InhR) Adult (≥21 years) Chronic 14.7 m 3 

### /day US EP A (2011d ) For general population exposures,
Table 6

- 1 (page 6

- 3): Average of mean long

- term exposure values for inhalation (males and females combined) for age classes 21

- <31,

31

- <41

, 41

- <51

, 51

- <61, 61

- <71

, and 71

- <81years.

Adult (≥21 years) Acute 0.74

m 3 

### /hour US EPA (2011d ) For consumer exposures, Table 6

- 2 (page 6

- 4): Average of mean sho rt

term exposure values for inhalation during light activity (males and females combined) for the age
classes 21

- <31, 31

- <41, 41

- <51, 51

- <61, 61

- <71, and 71

- <81 years. For
consumer scenarios: 0.74 m 3 

### /hour during product use (based on short

term exposure a t light activity level ; Table 6

- 2, page 6

- 4) and

0.611 m 3 

### /hour after product use.

Youth (16

- 20 years) Acute 16.3 m 3 

### /day US EPA (2011d ) Fo r general population exposures,
Table 6

- 1 (page 6

- 3): Mean long

term exposure value for inhalation (males and females combined) for age class 16

- <21 years. Children are typically considered to be non

users, however, for consumer exposures: 0.72 m 3 

### /hour du ring product use (based on short

- term exposure at light activity level ; Table 6

- 2, page 6

- 4) and 0.679

m 3 

### /hour after product use.

Youth (11

- 15 years) Acute 15.2 m 3 

### /day US EPA (2011d ) For general population exposures:
Table 6

- 1 (page 6

- 3): Mean long

term exposure value for inhalation (males and females combined) for age class 11

- <16 years. Children are
considered to be non

- users: 0.633 m 3 

### /hou r before and after product use.

### 23 Exposure Parameter Values Used in E

- FAST/CEM for TCE Modeling.

Exposure

Parameter Population Exposure Type Default
Value Source Comment

Child (6

- 10 years) Acute 12.0 m 3 

### /day US EPA (2011d ) For general population exposures:
Table 6

- 1 (page 6

- 3): Mean long

term exposure value for inhalation (males and females combined) for age class 6

- <11 years. Children are
considered to be non

- users: 0.500 m 3 

### /hour before and after product use.

Small child (3

- 5 years) Acute 10.1 m 3 

### /day US EPA (2011d ) For general population exposures:
Table 6

- 1 (page 6

- 3): Mean long

term exposure value for inhalation (males and females combined) for age clas s 3

- <6 years. Children are
considered to be non

- users: 0.421 m 3 

### /hour before and after product use.

Infant (1

- 2 years) Acute 8.5 m 3 

### /day US EP A (2011d ) For general population exposures:
Table 6

- 1 (page 6

- 3): Average of mean long

- term exposure values for inhalation (males and females combined) for age classes 1

- <2 and

2

- <3 years. Children are considered
to be non

- users: 0.35 m 3 

### /hour
before an d after product use.

Infant (<1 year) Acute 5.4 m 3 

### /day US EPA (2011d ) For general population exposures:
Table 6

- 1 (page 6

- 3): Mean long

term exposure values for inhalation (males and females combined) for the age class birth to <1 year.
Children are considered to be non

users: 0.23 m 3 

### /hour before and after product use.

Exposure Duration (ED) Adult (≥21 years) Chronic 57 years US EPA (2011d ) Adult lifetime exposure duration, based on life expectancy of 78 years (Table 18

- 1). Exposure from 21 to 78 years of age. Pr eviously,

18 years was used as the initiation
of this duration. For consumer

exposures

. Adult (≥21 years) Acute 1 day

_ Assumed 1

- day exposure for acute

scenarios.

### 24 Exposure Parameter Values Used in E

- FAST/CEM for TCE Modeling.

Exposure

Parameter Population Exposure Type Default
Value Source Comment

Youth (16

- 20 years) Acute 1 day

_ Assumed 1

- day exposure for acute

scenarios.

Youth (11

- 15 years) Acute 1 day

_ Assumed 1

- day exposure for acute

scenarios.

Child (6

- 10 years) Acute 1 day

_ Assumed 1

- day exposure for acute

scenarios.

Small child (3

- 5 years) Acute 1 day

_ Assumed 1

- day exposure for acute

scenarios.

Infant (1

- 2 years) Acute 1 day

_ Assumed 1

- day exposure for acute

scenarios.

Infant (<1 year) Acute 1 day

_ Assumed 1

- day exposure for acute

scenarios.

Carcinogenic Averaging Time (AT) Adult (≥21 years) Chronic 78 years US EPA (2011d ) Table 18

- 1 (page 18

- 1): Average of male and female life expectancy.
This recommended value is reflective of the average life expectancy of the general population. Data were col lected in 2007 and published in 2010 ( Xu et al. , 2010 )

Acute Averaging Time (AT) All Acute 1 day

_ Assumed 1

- day exposure for acute

scenarios.