UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                                    FORM 10-Q

(Mark One)

[X] QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15 (D) OF THE SECURITIES
    EXCHANGE ACT OF 1934

                  For the Quarterly Period Ended: JUNE 30, 2005
                                                  -------------

                                       or

[ ] TRANSITION REPORT PURSUANT TO SECTION 13 OR 15 (D) OF THE SECURITIES
    EXCHANGE ACT OF 1934

                  For the Period from __________ to __________


                         Commission File Number: 0-6333
                                                 ------


                            HYDRON TECHNOLOGIES, INC.
                            -------------------------
             (Exact name of Registrant as specified in its charter)


                  New York                                13-1574215
                  --------                                ----------
      (State or other jurisdiction of                  (I.R.S. Employer
       incorporation or organization)               Identification Number)


                         4400 34th Street North, Suite F
                             St Petersburg, FL 33714
                         -------------------------------
               (Address of Principal Executive Offices) (Zip Code)


                                 (954) 861-6400
                                 --------------
                         (Registrant's telephone number)


Indicate by check mark whether the Registrant (1) has filed all reports required
to be filed by Section 13 or 15 (d) of the Securities Exchange Act of 1934
during the preceding 12 months (or for such shorter period that the Registrant
was required to file such reports), and (2) has been subject to such filing
requirements for the past 90 days.                             [X] Yes   [_] No

Number of shares of common stock outstanding as of August 15, 2005: 11,320,336

<PAGE>

TABLE OF CONTENTS                                                          PAGE


Part I.  Financial Information
------------------------------

Item 1.  Financial Statements (Unaudited)

         Condensed Consolidated Balance Sheets -
           June 30, 2005 and December 31, 2004 ...........................   3

         Condensed Consolidated Statement of Operations -
           Three and six months ended June 30, 2005 and 2004 .............   4

         Condensed Consolidated Statements of Cash Flow -
           Six months ended June 30, 2005 and 2004 .......................   5

         Notes to Condensed Consolidated Financial Statements ............   6

Item 2.  Management's Discussion and Analysis of Financial Condition
           and Results of Operations .....................................  11

Item 4.  Controls and Procedures .........................................  18



Part II. Other Information
------------------------------

Item 6.  Exhibits ........................................................  19

Signatures ...............................................................  20

Certification of Chief Officers Pursuant to Section 302 of the
 Sarbanes-Oxley Act of 2002 and Item 307 of Regulation S-K ............... EX 31

Certification Pursuant to 18 U.S.C., Section 1350, as Adopted
 Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002 ............... EX 32


                                        2
<PAGE>
                          PART I. FINANCIAL INFORMATION

ITEM 1.  FINANCIAL STATEMENTS (UNAUDITED)

                            HYDRON TECHNOLOGIES, INC.
                      CONDENSED CONSOLIDATED BALANCE SHEETS

                                                    JUNE 30, 2005  DECEMBER 31,
                                                     (UNAUDITED)       2004
                                                    ------------   ------------
                                     ASSETS
Current Assets
  Cash and cash equivalents ......................  $    270,621   $    339,679
  Trade accounts receivable ......................        41,463          9,614
  Inventories ....................................       501,432        481,996
  Prepaid expenses and other current assets ......        29,808         67,190
                                                    ------------   ------------
      Total current assets .......................       843,324        898,479

Property and equipment, less accumulated
    depreciation of $211,819 and $209,329 at
    2005 and 2004, respectively ..................        10,183         12,673
Deposits .........................................        19,587         19,587
Deferred product costs, less accumulated
    amortization of $174,282 and $162,135 at
    2005 and 2004, respectively ..................       173,898        189,683

                                                    ------------   ------------
      Total Assets ...............................  $  1,046,992   $  1,120,422
                                                    ============   ============

                      LIABILITIES AND SHAREHOLDERS' EQUITY
Current liabilities
  Accounts payable ...............................        96,137   $     90,440
  Loans payable - net of unamortized discount ....       127,036            751
  Royalties payable ..............................        30,512         29,132
  Deferred revenues ..............................       137,719         91,180
  Accrued liabilities ............................       232,774        229,953
                                                    ------------   ------------
    Total current liabilities ....................       624,178        441,456

Commitments and contingencies
Minority interest in consolidated partnership ....       266,980        285,191

Shareholders' equity
  Preferred stock - $.01 par value
    5,000,000 shares authorized; no shares issued
    or outstanding ...............................             -              -
  Common stock - $.01 par value
    30,000,000 shares authorized; 9,320,336 shares
    issued and 9,320,336 shares outstanding at
    2005; and 2004, respectively .................        93,203         93,203
  Additional paid-in capital .....................    20,760,049     20,736,049
  Accumulated deficit ............................   (20,689,602)   (20,427,661)
  Treasury stock, at cost 10,000 at 2005
    and 2004 .....................................        (7,816)        (7,816)
                                                    ------------   ------------
    Total Shareholders' equity ...................       155,834        393,775

                                                    ------------   ------------
    Total liabilities and shareholders equity ....  $  1,046,992   $  1,120,422
                                                    ============   ============

      SEE ACCOMPANYING NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS

                                        3
<PAGE>
<TABLE>
                                      HYDRON TECHNOLOGIES, INC.
                           CONDENSED CONSOLIDATED STATEMENT OF OPERATIONS
                                             (Unaudited)
<CAPTION>

                                             THREE MONTHS ENDED JUNE 30,  SIX MONTHS ENDED JUNE 30,
                                                  2005          2004          2005          2004
                                              -----------   -----------   -----------   -----------
<S>                                           <C>           <C>           <C>           <C>
Net sales ..................................  $   275,781   $   336,098   $   531,695   $   722,230
Cost of sales ..............................      132,390       145,822       229,650       303,452
                                              -----------   -----------   -----------   -----------
Gross profits ..............................      143,391       190,276       302,045       418,778

Expenses
  Royalty expense ..........................       10,486        10,852        18,211        22,819
  Research and development .................       15,758        56,698        54,728       121,443
  Selling, general & administration ........      216,395       298,984       491,669       608,014
  Depreciation & amortization ..............        9,137         8,550        18,274        17,100
                                              -----------   -----------   -----------   -----------
    Total expenses .........................      251,776       375,084       582,882       769,376

                                              -----------   -----------   -----------   -----------
Operating loss .............................     (108,385)     (184,808)     (280,837)     (350,598)

Interest income - net of interest expense ..          264           842           686         1,661
                                              -----------   -----------   -----------   -----------
    Loss before income taxes ...............     (108,121)     (183,966)     (280,151)     (348,937)

Minority interest in net loss ..............        9,666             -        18,211             -
Income taxes expense .......................            -             -             -             -
                                              -----------   -----------   -----------   -----------
    Net loss ...............................  $   (98,455)  $  (183,966)  $  (261,940)  $  (348,937)
                                              ===========   ===========   ===========   ===========

Basic and diluted loss per share
  Net loss per common share ................  $     (0.01)  $     (0.02)  $     (0.03)  $     (0.04)
                                              ===========   ===========   ===========   ===========

Weighted average shares
  outstanding (basic and diluted) ..........    9,320,336     9,260,136     9,320,336     9,260,136
                                              ===========   ===========   ===========   ===========

                SEE ACCOMPANYING NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS

                                                  4
</TABLE>
<PAGE>
                            HYDRON TECHNOLOGIES, INC.
                 CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOW
                                   (Unaudited)


                                                       SIX MONTHS ENDED JUNE 30,
                                                          2005           2004
                                                       ---------      ---------
Operating activities
  Net loss .........................................   $(261,940)     $(348,937)
    Adjustments to reconcile net loss to
     net cash used by operating activities
      Minority Interest ............................     (18,211)             -
      Depreciation and amortization ................      18,274         17,100

    Change in operating assets and liabilities
      Trade accounts receivables ...................     (31,849)       (16,083)
      Inventories ..................................     (19,436)        (4,720)
      Prepaid expenses and other current assets ....      37,380        (15,001)
      Accounts payable .............................       5,699         81,183
      Royalties payable ............................       1,380         22,819
      Deferred revenues ............................      46,539        (70,567)
      Accrued liabilities ..........................       2,821         10,003
                                                       ---------      ---------
    Net cash used in operating activities ..........    (219,343)      (324,203)

Investing activities
  Deferred product costs ...........................           -         (4,740)
                                                       ---------      ---------
    Net cash used in investing activities ..........           -         (4,740)

Financing activities
    Loan payable , proceeds ........................     150,285         (1,930)
                                                       ---------      ---------
    Net cash provided by financing activities ......     150,285         (1,930)
                                                       ---------      ---------
Net decrease in cash and cash equivalents ..........     (69,058)      (330,873)

Cash and cash equivalents at beginning of period ...     339,679        964,723

                                                       ---------      ---------
Cash and cash equivalents at end of period .........   $ 270,621      $ 633,850
                                                       =========      =========

Supplemental cash flow information
Warrants issued in connection with loans payable ...   $  24,000              -


     SEE ACCOMPANYING NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS.

                                        5
<PAGE>
                            HYDRON TECHNOLOGIES, INC.
              NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS

NOTE A - BASIS OF PRESENTATION

         The accompanying unaudited financial statements have been prepared in
accordance with generally accepted accounting principles for interim financial
information and with the instructions to Form 10-Q and Article 10 of Regulation
S-X. Accordingly, they do not include all of the information and footnotes
required by generally accepted accounting principles for complete financial
statements. In the opinion of management of Hydron Technologies, Inc. (the
"Company"), all adjustments (consisting of normal recurring adjustments)
considered necessary for a fair presentation have been included. Operating
results for the three and six -month periods ended June 30, 2005 are not
necessarily indicative of the results that may be expected for the year ending
December 31, 2005. For further information, refer to the financial statements
and footnotes included in the Company's Annual Report on Form 10-K for the year
ended December 31, 2004.

Use of Estimates

         The preparation of financial statements in conformity with generally
accepted accounting principles requires management to make estimates and
assumptions that affect the amounts reported in the financial statements and
accompanying notes. Actual results could differ from those estimates.

Principles of Consolidation

         The accompanying consolidated financial statements for the period ended
June 30, 2005 and June 30, 2004 include the accounts of Hydron Technologies,
Inc. and its subsidiary, Hydron Royalty Partners Ltd LLP. All significant
intercompany accounts and transactions have been eliminated.

Recent Accounting Pronouncements

         In December 2004, the FASB issued SFAS No. 123R "Share-Based Payment"
("SFAS 123R"), a revision to SFAS No. 123 "Accounting for Stock-Based
Compensation" ("SFAS 123"), and superseding APB Opinion No. 25 "Accounting for
Stock Issued to Employees" and its related implementation guidance. SFAS 123R
establishes standards for the accounting for transactions in which an entity
exchanges its equity instruments for goods or services, including obtaining
employee services in share-based payment transactions. SFAS 123R applies to all
awards granted after the required effective date and to awards modified,
repurchased, or cancelled after that date. Adoption of the provisions of SFAS
123R is effective as of the beginning of the first interim or annual reporting
period that begins after June 15, 2005. The Company is currently in the process
of evaluating the potential impact that the adoption of SFAS 123R will have on
its consolidated financial position and results of operations.

         SFAS No. 154, Accounting Changes and Error Corrections, was issued in
May 2005 and replaces APB Opinion No. 20 and SFAS No. 3. SFAS No. 154 requires
retrospective application for voluntary changes in accounting principle in most
instances and is required to be applied to all accounting changes made in fiscal
years beginning after December 15, 2005. The Company's expected April 1, 2006
adoption of SFAS No. 154 is not expected to have a material impact on the
Company's consolidated financial condition or results of operations.

                                        6
<PAGE>
                            HYDRON TECHNOLOGIES, INC.
              NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS

NOTE B - INVENTORIES

         Inventories consist of the following:

                                               June 30,      December 31,
                                                 2005            2004
                                               --------      ------------

         Finished Goods ...............        $115,293        $ 93,312
         Raw materials and components .         386,139         388,684
                                               --------        --------

                                               $501,432        $481,996
                                               ========        ========

NOTE C - DISTRIBUTION

         The majority of the Company's products are currently sold in the United
States through its direct marketing channels (proprietary Catalog and the World
Wide Web site). The Company also sells its products to private label customers,
television retailers and, to a lesser extent, internationally through salons and
doctors offices.

NOTE D - EARNINGS PER SHARE

         On January 25, 2005, the Board of Directors, by unanimous consent,
re-authorized the issuance of 743,500 stock options from the 2003 Stock Plan to
Directors and Officers of the Company. Since the original approval date was more
than 12 months before the shareholder adoption of the 2003 Stock Plan, the
options had to be re-authorized to include them under the plan.

         There were no options granted to employees during the six months ended
June 30, 2005 that would require adjustments to the pro forma information
regarding net income and earnings per share required by FASB Statement No. 123.

NOTE E - ACCRUED LIABILITIES

         Accrued liabilities represent expenses that apply to the reported
period and have not been billed by the provider or paid by the Company. Accrued
liabilities consisted of the following:

                                             June 30,        December 31,
                                               2005              2004
                                             --------        ------------

         Dividends payable ........          $ 83,163          $ 83,163
         Director fees payable ....            91,018            81,016
         Legal fees ...............            28,867            40,754
         Other ....................            29,726            25,020
                                             --------          --------

                                             $232,774          $229,953
                                             ========          ========

                                        7
<PAGE>
                            HYDRON TECHNOLOGIES, INC.
              NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS

NOTE F - LOANS  PAYABLE

         On June 14, 2005, the Company borrowed an aggregate of One Hundred
Fifty Thousand Dollars ($150,000) (collectively, the "Loans") from three
individual lenders (collectively, the "Lenders"), including individuals who are
(i) the Chairman and Interim President, and a director of the Company, and (ii)
a director of the Company.

         In connection with the Loans, the Company issued to each of the Lenders
a promissory note in the principal amount of Fifty Thousand Dollars ($50,000)
(individually, a "Note" and collectively, the "Notes") providing for (a)
quarterly payments of interest at ten percent (10%) per annum and (b) repayment
of principal in a balloon payment on the second anniversary of the date of the
Notes. Under the terms of the Notes, the Company may elect to pay quarterly
interest to the holders of the Notes in shares of common stock, $.01 par value,
of the Company (the "Common Stock"), in an amount calculated by dividing the
amount of interest due and payable by ten cents ($.10). The Notes also provide
that, in the event of a default by the Company under the Notes, the holders may
elect to receive payment of principal and accrued and unpaid interest in shares
of Common Stock, in an amount calculated by dividing the amount of principal and
accrued and unpaid interest payable by the "Average Market Price" for a share of
Common Stock. Under the terms of the Notes, "Average Market Price" means the
average closing sale price for a share of Common Stock measured (x) over the
last ten trading days of the month preceding the interest payment date or, (y)
if no trading in the Common Stock has occurred during such period, the average
closing sale price on the last date on which a share of Common Stock was sold in
over-the-counter trading in the Common Stock. In the event that no shares of
Common Stock have traded in the over-the-counter market for a period of six
months or more, the Average Market Price shall be the fair market price for a
share of Common Stock as determined in good faith by the Board of Directors of
the Company.

         In addition, in connection with the Loans, each Lender received a
Common Stock Purchase Warrant (collectively, the "Warrants") entitling the
holder to purchase One Hundred Thousand (100,000) shares of Common Stock at an
exercise price of ten cents ($.10) per share for a five-year period. The
warrants were valued using the black scholes model at $24,000 , which will be
amortized over the life of the notes.

         The Notes and the Warrants each provide that in the event that the
Company shall grant "piggy back" registration rights to any other party to cause
the Company's Common Stock or any security exercisable or exchangeable for, or
convertible into, shares of Common Stock to be included in a registration
statement filed by the Company for sale by any selling shareholder or by the
Company, the Company will grant the holders of the Notes and Warrants similar
registration rights.

         Loans Payable consisted of the following:

                                               June 30,        December 31,
                                                 2005              2004
                                               --------        ------------

         Loan Payable .............            $150,000            $  -
         Accrued interest .........               1,036             751
         Less: unamortized discount
           on note payable ........              24,000               -
                                               --------            ----

                                               $127,036            $751
                                               ========            ====

                                        8
<PAGE>
                            HYDRON TECHNOLOGIES, INC.
              NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS

NOTE G - GOING CONCERN

         The accompanying condensed financial statements were prepared assuming
that the Company will continue as a going concern. This basis of accounting
contemplates the recovery of the Company's assets and the satisfaction of its
liabilities in the normal course of operations.

         The Company anticipates that present working capital balances and
internally generated funds will be sufficient to meet our working capital needs
for the next three months and maybe longer based on management decisions and
sales. Beyond that point, it will be necessary to consummate a merger, sell
selected assets, or obtain an infusion of capital. The Company's independent
accountants issued a "going concern" opinion since the Company has incurred
significant losses over the past five years and generates a negative cash flow
on a monthly basis.

         On January 28, 2005, the Company entered into a marketing agreement
with Clinical Results, Inc. and Bioceutical Research, Inc. to license its
technology and the Hydron branded products, respectively. Any impact on cash
flow is not expected to be realized for six to nine months. In addition, the
Company has lowered its operating expenses by reducing research and development
and payroll costs.

         The Company is considering several additional options to resolve the
negative cash flow, including merging with parties that have a broad channel of
distribution, forming a new private entity and transferring the operating assets
to it, then selling the public shell, and selling one or more selected assets.
One of these alternatives and/or an infusion of additional capital will be
required in order to generate the cash required in the short term. On July 1,
2005 the Company acquired Clinical Results, Inc. (see Note H).

         Accordingly, there are no assurances that the Company will be
successful in achieving the above plans, or that such plans, if consummated,
will enable the Company to obtain profitable operations or continue as a going
concern.

NOTE H - SUBSEQUENT EVENTS

         On July 1, 2005 the Company acquired Clinical Results, Inc. (CRI), a
St. Petersburg, Florida-based company. CRI is a privately held product
development laboratory and contract manufacturer of cosmeceutical and other
personal care products. CRI's clients range from mass market retailers to
marketers of certain health food store brands, and marketers of high end brands
such as Hydron.

         While CRI will continue providing contract services for its customer
base, Hydron Technologies will benefit from lower manufacturing costs, and be
better positioned to expand the sale of its skin care treatments beyond its
historical direct response TV and catalog operations by utilizing CRI's broker
network.

                                        9
<PAGE>
                            HYDRON TECHNOLOGIES, INC.
              NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS

         Under the terms of the agreement, Hydron Technologies acquired all of
the outstanding shares of capital stock of CRI in consideration of an aggregate
of two million newly-issued shares of the Company, in a transaction exempt from
registration under the securities laws. Such shares are subject to transfer
restrictions unless registered under federal and applicable state securities
laws or sold in a transaction exempt from registration. Additionally, Hydron
restructured both its management and its Board of Directors. David Pollock,
currently President of CRI, become Chief Executive Officer of the Company, while
remaining President of CRI, and joined Hydron's Board, replacing Joshua Rochlin
who resigned from the Board on March 31, 2005. Dr. Douglas Reitz, CRI's
co-owner, become Executive Vice President of Hydron and Richard Banakus retained
the titles of Interim President and Chairman of the Board, of the Company.

         Effective August 5, 2005, Mr. Terrence S. McGrath , the Company's Chief
Operating Officer resigned in order to pursue other career opportunities. Mr.
McGrath's responsibilities were assumed by Mr. David E. Pollock, Hydron's Chief
Executive Officer.

                                       10
<PAGE>

ITEM 2.  MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS
         OF OPERATIONS

BUSINESS

         The Company's primary focus had been to conduct research and
development into products and medical applications utilizing its patented tissue
oxygenation technology.

         The Company's research and development efforts during 2004 concentrated
on accumulating data for a Food and Drug Administration (FDA) application
related to the Company's oxygenation technology. A formal Request For
Designation (RFD) was filed with the FDA in September 2004 to request that the
FDA formally designate the Hydron MicroO2 Oxygenation Apparatus as a medical
device. The FDA agreed in October. On January 10, 2005, the Company attended a
Pre-Investigational Device Exemption meeting with the FDA to present the device,
however, a clear pathway for safety and clinical research requirements could not
be determined at that time. It was suggested that filing a complete 510(k)
application would provide the FDA with an opportunity to review additional
information from Hydron. The Company is considering if and when to pursue the
510(k) filing.

         The Company is refocusing its efforts on its other proprietary
technologies which include: patented polymer skin care formulas that provide
superior skin moisturization benefits and sunscreen delivery; a patented formula
for a wrinkle reduction serum, and patent-pending technology associated with an
evaporating emulsifier used in cosmetic treatments and acne products.

         The Company markets a broad range of cosmetic and oral health care
products using a moisture-attracting ingredient (the "Hydron(R) polymer") and a
topical delivery system for active ingredients, including pharmaceuticals. The
Company holds U.S. and international patents on, what Management believes is,
the only known cosmetically acceptable method to suspend the Hydron polymer in a
stable emulsion for use in personal care/cosmetic products. The Company is
developing other personal care/cosmetic products for consumers using its
patented technology and would, when appropriate, either seek licensing
arrangements with third parties, or develop and market proprietary products
through its own efforts. Management believes that because of their unique
properties, products that utilize the Hydron polymer have the potential for wide
acceptance in consumer and professional health care markets.

Catalog Sales - The Company's full-color brochure offers personal care products
for sale directly to consumers. The brochure also provides information on new
products, educates consumers on proper skin care, and facilitates consumer
re-ordering. The Company sells its products on the World Wide Web and regularly
transmits E-mail broadcasts to its customer base. The Company is continuing to
explore new ways to enhance Catalog sales and operations through retail
distribution of its brands and formula technologies.

Private Label Contracting - Effective March 1, 2001, the Company entered into an
agreement with Reliv International, Inc ("Reliv") to develop and manufacture a
line of private label skin care products under their brand name, ReversAge(R).
Reliv is a public company traded on NASDAQ (symbol RELV). Private label sales
represented approximately 19.2% of Hydron's total annual sales in 2004. Private
label sales accounted for 16.7% of total sales during the six months ended June
30, 2005.

                                       11
<PAGE>

International - The Company sells products to an Australia-based health and
beauty products distributor for retail sale in salon stores and medical offices
in Australia and New Zealand. The Company also distributes dental products in
Spain and, to a lesser extent, other countries. Although this category is not
significant at this time, Management believes that it will expand with the
introduction of the Company's brands and technologies through retail
distribution channels.

Retail - The Company has established minor levels of retail distribution.
Initially, the Company sold product on a limited, promotional basis to several
retailers utilizing excess inventory and current packaging configurations. It is
anticipated that any significant retail effort involving core Hydron products
would require investment in repackaging.

Licensing - Effective January 28, 2005, the Company entered into a non-exclusive
licensing agreement with Clinical Results, Inc. ("CRI"), which allows for
certain Hydron cosmetic skincare technologies, sold and manufactured by CRI, to
be offered to third parties under private label contracts. The Company receives
royalties based on wholesale sales by CRI to its customers. The agreement
includes the patented Hydron polymer and sunscreen technology, patented line
smoothing technology, and patent-pending emulsifier technology.

         Effective January 28, 2005 Hydron licensed Bioceutical Research, Inc.
("BRI") the non-exclusive right to market Hydron(R) and Hydronamins(R) branded
products to retail accounts, including drug stores, mass-merchandisers, club
stores, and salon/spa accounts. BRI will pay Hydron royalties on wholesale sales
while undertaking responsibility for manufacturing, marketing, and sales.

RESULTS OF OPERATIONS

         Total net sales for the three months ended June 30, 2005 were $275,781,
a decrease of $60,317 or 17.9% from net sales of $336,098 for the three months
ended June 30, 2004 Skin care products net sales for the three months ended June
30, 2005 were $248,200, a decrease of $52,758 or 17.5% from sales of $300,958
for the three months ended June 30, 2004. Professional products net sales for
the three months ended June 30, 2005 were $1,542, a decrease of $632 or 29.1%
from sales of $2,174 for the three months ended June 30, 2004. Shipping and
handling revenues for the three months ended June 30, 2005 were $25,787, a
decrease of $7,179 or 21.8% from shipping and handling revenues of $32,966 in
the three months ended June 30, 2004.

         For the six months ended June 30, 2005, total net sales were $531,695,
a decrease of $190,535 or 26.4% from net sales of $722,230 for the six months
ended June 30, 2004. Skin care products net sales for the six months ended June
30, 2005 were $473,844, a decrease of $181,371 or 27.7% from sales of $655,215
for the six months ended June 30 2004. Professional products' net sales for the
six months ended June 30, 2005 were $2,730, an increase of $556 or 25.6% from
sales of $2,174 for the six months ended June 30, 2004. Shipping and handling
revenues for the six months ended June 30, 2005 were $53,428, a decrease of
$9,588 or 15.2% from shipping and handling revenues of $63,016 in the six months
ended June 30, 2004.

                                       12
<PAGE>

         Skin care products sales consist primarily of catalog sales and private
label sales. During the three months ended June 30, 2005, direct marketing
catalog sales decreased by $42,274 or 19.8% from $213,808 for the three months
ended June 30, 2004 to $171,534. Private label sales for the three months ended
June 30, 2005 were $76,666, a decrease of $10,484 or 12.0% from private label
sales of $87,150 for the same period last year. These sales tend to fluctuate
from quarter to quarter as purchase orders for individual items cover more than
one year's supply. Purchase orders are received only approximately four to six
times a year for the seven items in the line.

         For the six months ended June 30, 2005, direct marketing catalog sales
decreased by $86,527 or 19.4% from $445,683 last year to $359,156 this year.
Private label sales for the six months were $114,687, a decrease of $94,845 from
private label sales of $209,532 for the same period last year. As stated above,
these private label sales tend to fluctuate significantly from quarter to
quarter.

         Cost of sales was $132,390 for the three months ended June 30, 2005, a
decrease of $13,432 or 9.2% from cost of sales of $145,822 for the three months
ended June 30, 2004. Cost of sales was 48.0% of total sales for the three months
ended June 30, 2005 compared to 43.4% for the three months ended June 30, 2004.
The increase in cost of sales percentage reflects the impact of this period's
private label sales, which included unusually high product cost (84.7% of
sales), versus the product cost of catalog sales (18.9% of catalog sales.)
Shipping and handling costs for the second quarter of 2005 were $28,308, a
decrease of $6,899 or 19.6% from shipping and handling costs of $35,207 for the
same period in 2004. This decrease reflects the 20.7% decline in catalog sales
offset by savings realized by performing more of the shipping and handling tasks
in house.

         For the six months ended June 30, 2005 cost of sales was $229,650, a
decrease of $73,802 or 24.3% from cost of sales of $303,452 for the six months
ended June 30, 2004. Cost of sales was 43.2% of total sales for the six months
ended June 30, 2005 compared to 42.0% for the six months ended June 30, 2004.
The increase in cost of sales percentage reflects the impact of this period's
private label sales as stated above. Shipping and handling costs for the six
months were $60,278, a decrease of $7,661 or 11.3% from shipping and handling
costs of $67,939 for the same period in 2004. This decrease reflects the 19.4%
decline in catalog sales offset by savings realized by performing more of the
shipping and handling tasks in house.

         The Company's overall gross profit margin decreased to 52.0% of net
sales for the three months ended June 30, 2005 versus 56.6% for the three months
ended June 30, 2004. This is due primarily to the lower margin private label
sales and, to a lesser degree the costs discussed above. For the six month ended
June 30, 2005 the overall gross profit margin decreased similarly to 56.8% of
net sales versus 58.0% for the same period in 2004.

         Royalty expenses for the three months ended June 30, 2005 were $10,486
a decrease of $366, or 3.4%, from royalty expenses of $10,852 for the three
months ended June 2004. The decrease in royalty expenses is consistent with the
decrease in skin care product sales for the same period. Royalty expenses for
the six months ended June 30, 2005 were $18,211 a decrease of $4,608 or 20.2%,
from royalty expenses of $22,819 for the six months ended June 2005. The
decrease in royalty expenses is consistent with the decrease in skin care
product sales for the same period.

                                       13
<PAGE>

         Research and development ("R&D") expenses reflect the Company's efforts
to identify new product opportunities, obtain regulatory approval, develop and
package the products for commercial sale, perform appropriate efficacy and
safety tests, and conduct consumer panel studies and focus groups. R&D expenses
for the three months ended June 30, 2005 were $15,758, a decrease of $40,940 or
72.2% from R&D expenses of $56,698 for the three months ended June 30, 2004. For
the six months ended June 30, 2005 R&D expenses were $54,728 a decrease of
$66,715 or 54.9% from R&D expenses of $121,443 for the same period last year.
This decrease was due principally to the Company eliminating the use of outside
FDA consultants in association with its oxygenation technology during 2005
versus 2004. The amount of annual R&D expenses will vary year to year depending
on the Company's research requirements.

         Selling, general, and administrative ("SG&A") expenses for the three
months ended June 30, 2005 were $216,395, representing an decrease of $82,589 or
27.6% from SG&A expenses of $298,984 for the three months ended June 30, 2004.
Employment expense was $80,180 for the three months ended June 30, 2005, a
decrease of $56,400 or 41.3% from $136,580 for the three months ended June 30,
2004. This decrease was due primarily to the elimination of two salaried
positions in order to reduce operating costs. Postage expense was $12,004 for
the three months ended June 30, 2005, a decrease of $5,956 or 33.2%, from
$17,960 for the three months ended June 30, 2004. This decrease was related
principally to a new catalog marketing strategy, which reduces mailing frequency
to customers who have not purchased in the last 24 months. All other expenses
were $124,211 for the three months ended June 30, 2005, a decrease of $20,233 or
14.0% from $144,444 for the three months ended June 30, 2004. For the six months
ended June 30, 2004 selling, general, and administrative expenses were $491,669,
a decrease of $116,345 or 19.1% from $608,014 for the same period last year.

         Depreciation and amortization expense was $9,137 for the three months
ended June 30, 2005, an increase of $587 or 6.9% from $8,550 for the three
months ended June 30, 2004. For the six months ended June 30, 2005 depreciation
and amortization were $18,274, an increase of $1,174 or 6.9% from $17,100 for
the same period last year.

         Net interest income was $264 for the three months ended June 30, 2005
compared to net interest income of $842 for the three months ended June 30,
2004. The Company maintains a conservative investment strategy with respect to
its cash balances, deriving investment income primarily from U.S. Treasury
securities.

         The Company had a net loss of $98,455, representing a decrease of
$85,511 or 46.5% for the three months ended June 30, 2005 from the net loss of
$183,966 for the three months ended June 30, 2004, a result primarily of the
factors discussed above.

         For the six months ended June 30, 2005, the company had a net loss of
$261,940 a decrease of $86,997 or 24.9% from net loss of $348,937 for the six
months ended June 30, 2004. The decrease in the net loss is a result primarily
of the factors discussed above.

                                       14
<PAGE>

LIQUIDITY AND FINANCIAL RESOURCES

         The Company anticipates that present working capital balances and
internally generated funds will be sufficient to meet its working capital needs
for the next three months, perhaps longer based on management decisions and
order flow. Beyond that point, it will be necessary to consummate a merger, sell
selected assets, or obtain an infusion of capital. On July 1, 2005 the Company
acquired Clinical Results, Inc (see Note H). The Company's independent
accountants issued a "going concern" opinion since the Company has incurred
significant losses over the past five years and generates a negative cash flow
on a monthly basis.

         The Company's working capital was approximately $219,146 as of June 30,
2005, including cash and cash equivalents of approximately $270,621. Cash used
by operating activities was $219,343. Net proceeds from financing activities
were $150,285.

         The Company does not have any material debt other than the loan payable
of $150,000 borrowed from three investors on May 2005 (see Note F), long-term
capital leases, or long-term operating leases. The lease on the current office
facility expires August 31, 2005 and the Company did not renew the lease.
Effective August 5, 2005, the Company relocated its offices to St Petersburg,
Fl. There are no capital expenditures under construction and no long-term
commitments other than royalty payments under an agreement with Valera
Pharmaceuticals, Inc. The Company does not have any lines of credit. There are
no purchase order commitments that exceed 90 days.

         On December 10, 2002, the Company completed a non-brokered private
placement of 1,750,000 Units at $.20 per Unit ($350,000) to several accredited
investors. Each Unit is comprised of one share of Common Stock and one
three-year option to buy one additional common share at $.20. As of March 31,
2005, all 1,750,000 options were outstanding.

         On November 14, 2003, the Company completed a non-brokered private
placement of 2,210,000 Units at $.50 per Unit ($1,105,000) to accredited
investors. Each Unit is comprised of one share of Common Stock and one five-year
warrant to buy one additional common share at $1.00. As of June 30, 2005, all
2,210,000 warrants were outstanding.

         The Company registered these outstanding shares and 4,481,500
underlying shares of outstanding warrants/options with the Securities and
Exchange Commission effective July 22, 2004. The warrants/options are a future
source of capital for the Company and could generate up to $2,560,000 if they
are exercised.

         The Company's independent accountants issued a "going concern" opinion
since the Company has incurred significant losses over the past five years and
generates a negative cash flow on a monthly basis. The ability of the Company to
continue as a going concern is dependent upon increasing sales, managing
operating expenses and obtaining additional equity financing.

         Management's plan includes implementing one or more of the following
elements:

      o  Conducting merger negotiations with third parties that have
         distribution networks in place. The synergies, combined sales, and
         reduced overhead would create a solid operational foundation and
         improved financial position.

                                       15
<PAGE>

      o  Forming a new private entity and transferring the operating assets to
         it, then selling the public shell to one of the interested parties.

      o  Selling one or more selected assets.

      o  Obtaining an infusion of capital that will sustain the Company's
         operation until the newly established licensing arrangements can
         produce positive cash flow.

      o  Continuing to reduce overhead and operating costs.

         There can be no assurances that management's plan will be successful
and the Company's actual results could differ materially. No estimate has been
made to the financial statements to account for the possibility that the plan
may be unsuccessful.

CAUTIONARY STATEMENT REGARDING FORWARD-LOOKING STATEMENTS

         The statements contained in this Report on Form 10-K that are not
purely historical are forward-looking statements within the meaning of Section
27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act
of 1934, including statements regarding the Company's expectations, hopes,
intentions, beliefs or strategies regarding the future, including, without
limitation, its plans regarding distribution and marketing of its products and
the development, acquisition and marketing of new products. Forward-looking
statements include the Company's liquidity, anticipated cash needs and
availability, and the anticipated expense levels under the heading "Management's
Discussion and Analysis of Financial Condition and Results of Operations." All
forward-looking statements included in this document are based on information
available to the Company on the date of this report, and the Company assumes no
obligation to update any such forward-looking statement. It is important to note
that the Company's actual results could differ materially from those expressed
or implied in such forward-looking statements.

         Each forward-looking statement reflects the Company's current view of
future events and is subject to risks, uncertainties, and other factors that
could cause actual results to differ materially from any results expressed or
implied by the forward-looking statements. Important factors that could cause
actual results to differ materially from the results expressed or implied by any
forward-looking statements include:

      o  The volatility of the price of the Company's Common Stock;

      o  The Company's ability to fund future growth;

      o  The Company's ability to be profitable;

      o  The Company's ability to attract and retain qualified personnel;

      o  The Company's ability to effectively relocate operations to its new
         facility in St Petersburg, Fl;

      o  The ability of the new management to effectively execute the Company's
         operating plan and continue operations;

                                       16
<PAGE>

      o  General economic conditions in the medical and cosmetic markets;

      o  Market demand for and market acceptance of the Company's products;

      o  Legal claims against the Company, including, but not limited to claims
         of patent infringement;

      o  The Company's ability to protect its intellectual property;

      o  Defects in the Company's products;

      o  The Company's obligation to indemnify certain customers;

      o  The Company's dependence on contact manufacturers and suppliers;

      o  The Company's dependence on a small number of customers for revenue
         with respect to its products;

      o  The Company's ability to develop and maintain relationships with key
         vendors;

      o  New regulations and legislation;

      o  General economic and business conditions;

      o  Other risks and uncertainties disclosed in the Company's Annual Report
         on Form 10-K for the year ended December 31, 2004 and in the Company's
         other filings with the SEC.

         All subsequent forward-looking statements relating to the matters
described in this document and attributable to us or to persons acting on the
Company's behalf are expressly qualified in their entirety by such factors. The
Company has no obligation to publicly update or revise these forward-looking
statements to reflect new information, future events, or otherwise, except as
required by applicable Federal securities laws, and the Company cautions you not
to place undue reliance on these forward-looking statements.

RECENT ACCOUNTING PRONOUNCEMENTS

         In December 2004, the FASB issued SFAS No. 123R "Share-Based Payment"
("SFAS 123R"), a revision to SFAS No. 123 "Accounting for Stock-Based
Compensation" ("SFAS 123"), and superseding APB Opinion No. 25 "Accounting for
Stock Issued to Employees" and its related implementation guidance. SFAS 123R
establishes standards for the accounting for transactions in which an entity
exchanges its equity instruments for goods or services, including obtaining
employee services in share-based payment transactions. SFAS 123R applies to all
awards granted after the required effective date and to awards modified,
repurchased, or cancelled after that date. Adoption of the provisions of SFAS
123R is effective as of the beginning of the first interim or annual reporting
period that begins after June 15, 2005. The Company is currently in the process
of evaluating the potential impact that the adoption of SFAS 123R will have on
its consolidated financial position and results of operations.

                                       17
<PAGE>

         SFAS No. 154, Accounting Changes and Error Corrections, was issued in
May 2005 and replaces APB Opinion No. 20 and SFAS No. 3. SFAS No. 154 requires
retrospective application for voluntary changes in accounting principle in most
instances and is required to be applied to all accounting changes made in fiscal
years beginning after December 15, 2005. The Company's expected April 1, 2006
adoption of SFAS No. 154 is not expected to have a material impact on the
Company's consolidated financial condition or results of operations

ITEM 4.  CONTROLS AND PROCEDURES

         As of the end of this period, the Company carried out an evaluation,
under the supervision and with the participation of management, including its
Interim President, of the effectiveness of the design and operation of the
Company's disclosure controls and procedures pursuant to Exchange Act Rule
13a-14. Based upon that evaluation, the Interim President concluded that the
Company's disclosure controls and procedures are effective to timely alert them
to material information required to be included in the Company's Securities
Exchange Act of 1934 filings.

         Disclosure controls and procedures (as defined in the Exchange Act
Rules 13a-14(c) and 15d-14(c)) are controls and other procedures that are
designed to ensure that information required to be disclosed in our reports
filed or submitted under the Exchange Act are recorded, processed, summarized
and reported, within the time periods specified in the Securities and Exchange
Commission's rules. Disclosure controls and procedures include, without
limitation, controls and procedures designed to ensure that information required
to be disclosed in our reports filed under the Exchange Act is accumulated and
communicated to management to allow timely decisions regarding required
disclosure.

         The Certifying Officer has also indicated that there were no
significant changes in our internal controls or other factors that could
significantly affect such controls subsequent to the date of their evaluation,
and there were no corrective actions with regard to significant deficiencies and
material weaknesses.

         Our management, including the Certifying Officer, does not expect that
our disclosure controls or our internal controls will prevent all error and
fraud. A control system, no matter how well conceived and operated, can provide
only reasonable, not absolute, assurance that the objectives of the control
system are met. In addition, the design of a control system must reflect the
fact that there are resource constraints, and the benefits of controls must be
considered relative to their costs. Because of the inherent limitations in all
control systems, no evaluation of controls can provide absolute assurance that
all control issues and instances of fraud, if any, within a company have been
detected. These inherent limitations include the realities that judgments in
decision-making can be faulty, and that breakdowns can occur because of simple
error or mistake. Additionally, controls can be circumvented by the individual
acts of some persons, by collusion of two or more people or by management
override of the control. The design of any systems of controls also is based in
part upon certain assumptions about the likelihood of future events, and their
can be no assurance that any design will succeed in achieving its stated goals
under all potential future conditions. Over time, control may become inadequate
because of changes in conditions, or the degree of compliance with the policies
or procedures may deteriorate. Because of these inherent limitations in a
cost-effective control system, misstatements due to error or fraud may occur and
not be detected.

                                       18
<PAGE>
                           PART II. OTHER INFORMATION

ITEM 6.  EXHIBITS

31.1     Certification of Interim President, Principal Financial and Accounting
         Officer pursuant to Section 302 of the Sarbanes-Oxley Act of 2002 and
         Item 307 of Regulation S-K (filed herewith)

32.1     Certification of Interim President, Principal Financial and Accounting
         Officer Pursuant to 18 U.S.C., Section 1350, as Adopted Pursuant to
         Section 906 of the Sarbanes-Oxley Act of 2002 (filed herewith)


                                       19
<PAGE>
                                   SIGNATURES

         Pursuant to the requirements of the Securities Exchange Act of 1934,
the Registrant has duly caused this report to be signed on its behalf by the
undersigned thereunto duly authorized.


                                      HYDRON TECHNOLOGIES, INC.


                                      /s/: Richard Banakus
                                      --------------------
                                      Richard Banakus
                                      Chairman of the Board, Interim President
                                      Principal Financial and Accounting Officer


Dated: August 15, 2005


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