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                                                                   EXHIBIT 10.21


                           COPYRIGHT LICENSE AGREEMENT

      This Agreement (this "Agreement") is made effective as of December 29,
1997 (the "Effective Date"), by A.D.A.M. SOFTWARE, INC., a Georgia corporation
("ADAM") and KAINOS LABORATORIES, INC., a Japanese corporation ("KAINOS").


                                    RECITALS

A.    ADAM is engaged in the business of developing, distributing, and marketing
computer software products in the form of computer programs and written
documentation relating to their use.

B.    ADAM has acquired from Mosby Consumer Health (MCH) the rights of Applied
Medical Informatics, Inc., a Utah corporation ("AMI"), with respect to three
computer software products, known as "Medical HouseCall", "Pediatric HouseCall" 
and "Illiad" (those three products are referred to in this Agreement as the 
"Products"). KAINOS wishes to acquire an exclusive license to use and modify the
Products to create and manufacture Japanese language versions of the Products
and derivative products in the Japanese language, and the exclusive right to
distribute Japanese language versions of the Products throughout the world, and
ADAM is willing to grant the license and distribution rights in the Japanese
language versions of the Products to KAINOS under the terms and conditions of
this Agreement.  These rights being granted to KAINOS include all of ADAM's
rights in and to the current localized Japanese versions and derivatives of the
Products developed during the period when MCH owned the rights in the Products.
KAINOS also wishes to acquire the right to distribute English language versions
of the Products in Japan, and ADAM is willing to grant such rights under the
terms of this Agreement.

      NOW, THEREFORE, in consideration of the premises and mutual covenants and
agreements set forth in this Agreement, KAINOS and ADAM agree as follows:



                                    Section 1
                            RIGHTS GRANTED TO KAINOS

      1.1   Grant.  Subject to the terms and conditions of this Agreement, ADAM
grants to KAINOS the following exclusive license and related rights with respect
to the Products in the Territory:

             (a)  to manufacture and reproduce, or have manufactured and
      reproduced on its behalf, copies of Japanese language versions of the
      Products (including any modified versions of the Products produced by
      KAINOS pursuant to Section 1.1(c) below);



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             (b)  to market, sell and distribute Japanese language versions of
      the Products (including any modified versions of the Products in the
      Japanese language produced by KAINOS pursuant to Section 1.1(c) below) in
      the Territory during the term of this Agreement.  KAINOS shall have the
      exclusive right to distribute, by any means or method of distribution, the
      Japanese language versions of the Products (including any modified
      versions of the Products in the Japanese language produced by KAINOS
      pursuant to Section 1.1(c) below) in the Territory, including exclusive
      copyrights with respect to the Japanese language versions of the Products
      (including any modified versions of the Products in the Japanese language
      produced by KAINOS pursuant to Section 1.1(c) below);

             (c)  to modify the Products in the Japanese language (which may
      include a limited amount of English language where the English language
      word or term cannot be properly translated into the Japanese language, or
      which enhances the functions of the Japanese language version) and create
      derivative works of the Products in the Japanese language, including
      without limitation localized versions of the Products in the Japanese
      language (which may include a limited amount of English language where the
      English language word or term cannot be properly translated into the
      Japanese language, or which enhances the functions of the Japanese
      language version) designed for the Japanese market, and to manufacture and
      reproduce, market, distribute and sell such modifications to and
      derivatives of the Products (including localized versions of the Products)
      in the Japanese language in the Territory during the term of this
      Agreement; provided that any such modifications and derivatives (including
      localized versions) must be in the Japanese language.

      1.2   Sublicenses.  ADAM hereby grants KAINOS the right to sublicense the
manufacturing, reproduction and distribution (through multiple tiers of
sublicenses) of the Japanese language versions of the Products in the Territory
during the term of this Agreement; provided that KAINOS must cause all
sublicenses to comply with the terms and conditions of this Agreement.

      1.3   Distribution Rights.  ADAM grants to KAINOS the exclusive right to
distribute copies of the English language versions of the "Illiad" Product in
Japan only, subject to the terms and conditions of this Agreement.  ADAM also
grants to KAINOS the exclusive right to distribute copies of the English
language versions of the "Medical Housecall" and "Pediatric Housecall" Products
in Japan only, subject to (1) the existing rights of Mindscape under the
worldwide distribution agreement between Mindscape and ADAM which expires on
December 31, 2000 (the "Mindscape Distribution Agreement"), and (2) the terms
and conditions of this Agreement.  Upon the termination of the existing 
Mindscape Distribution Agreement, KAINOS will have the exclusive right to
distribute the English language versions of the Products in Japan only.

All copies of English language versions of the Products distributed by KAINOS in
Japan must be obtained by KAINOS from ADAM pursuant to this Agreement; KAINOS
will not have the right to manufacture, make or have made copies of the English
language versions of the Products.  ADAM will furnish KAINOS with 100 copies of
the English language versions of each of the Products, solely for distribution
in Japan, free of charge, at KAINOS' request.  Thereafter, the per unit royalty
for the English language versions of Medical Housecall and Pediatric Housecall
will be U.S. $12.00 per unit.  Units of the English language version of Iliad 
may be purchased by



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KAINOS at a royalty equal to the average price charged by ADAM in the U.S. to
resellers of that Product.  The Products will be shipped FOB ADAM by a method
specified by KAINOS.  KAINOS will be responsible for shipping and insurance.

      1.4   No Implied Rights.  Except as specifically set forth in this
Agreement, no express or implied license or right of any kind is granted to
KAINOS regarding the Products or any of the trademarks of ADAM, including, but
not limited to, any right to know, use, produce, receive, reproduce, copy,
market, sell, distribute, transfer, translate, modify, adapt, disassemble,
decompile, or reverse-engineer the Products or obtain possession of any source
code or other technical material relating to the Licensed Products.  KAINOS
specifically acknowledges and agrees that the rights granted under this
Agreement are limited to the Japanese language versions of the Products
("Medical HouseCall," "Pediatric HouseCall," and "Illiad"); the rights granted
do not apply to any other products of ADAM.


                                    Section 2

                         OBLIGATIONS OF KAINOS AND ADAM

      2.1   Marketing.  KAINOS will use reasonable efforts to promote and market
(1) the modified Japanese language versions of the Products and derivatives of
the Products in the Japanese language produced by KAINOS in the Territory, and
(2) the English language versions of the Products in Japan.  KAINOS will bear 
the cost of all marketing and advertising expenses related to the Japanese
language versions and derivatives of the Products in the Japanese language
produced by KAINOS and the English language versions of the Products distributed
by KAINOS.

      2.2   Product Support and Warranty.  KAINOS shall be solely responsible
for supporting all end-users of the Products distributed by KAINOS and for
providing all warranty coverage and support in accordance with the customary
end-user warranty included with the Products.  ADAM will furnish end-user 
support and warranty coverage (returns of defective products) for copies of
English-language versions of the Products distributed in Japan, in accordance
with ADAM's standard end-user warranty and support policies.  ADAM will provide
to KAINOS, during the term of this Agreement and in a timely manner, all
revisions, updates, enhancements or fixes to the Products that ADAM may, in its
sole discretion, elect to develop, or have developed, and incorporate, or have
incorporated, in the English language versions of the Products for general
distribution in the United States; however, ADAM is not obligated to undertake
any such revisions, updates, enhancements or fixes.  ADAM will also use its
commercially reasonable efforts to furnish KAINOS with access to any technical
materials or information about the Products that is in ADAM's possession and
control (including using reasonable efforts to obtain such materials or
information from third parties) and would be useful to KAINOS in the development
and manufacture of the Japanese language versions of the Products (including
modifications of the Products developed by KAINOS).  If the assistance requested
by KAINOS exceeds 10 hours in any calendar quarter, ADAM will be compensated at
its standard contracted services rate (currently U.S.$125 per hour).


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      2.3   Packaging.  KAINOS will develop any new packaging required for the
Japanese language versions of the Products or derivatives of the Products in the
Japanese language produced by KAINOS.  Any copies of the English language
versions of the Products distributed by KAINOS in Japan in accordance with this
Agreement must be distributed in the original packaging furnished by ADAM;
KAINOS will not have the right to repackage such copies of the English language
versions of the Products without authorization from ADAM.

      2.4   Notices.  KAINOS will maintain any copyright and trademark notices
which are included on and in the Products or otherwise specified by ADAM in
writing from time to time.

      2.5   No Authority to Bind A.D.A.M.  KAINOS has and will exercise no
authority to make statements, warranties or representations concerning the
Products that exceed or are inconsistent with the marketing materials or
technical specifications provided to KAINOS by ADAM.  KAINOS has and will
exercise no authority to bind ADAM to any undertaking or performance with
respect to the Products.

      2.6   Deliverables.  ADAM will provide, upon execution of this Agreement,
KAINOS all object code, source code, related technical materials in ADAM's
possession relating to the development of the current versions of the Products,
in electronic form, as listed on Exhibit A. ("Deliverables")


                                    Section 3
                               PROPRIETARY RIGHTS

      3.1   Ownership.  Notwithstanding any provision in this Agreement to the
contrary, as between KAINOS and ADAM, ADAM will retain and own all worldwide
right, title and interest in and to the Products and the Trademarks, and all
intellectual property and other rights therein, including but not limited to
copyrights, patents, and trade secrets in the Products and derivatives thereof
(both object code and source code form), and the Collateral Materials, including
all copies and all portions thereof, and nothing in this Agreement will vest
title in KAINOS to any rights therein, except as expressly set forth in this
Agreement.  KAINOS will own all rights in any derivative works of the Products 
in the Japanese language developed by KAINOS in accordance with Section 1.1(c);
however, KAINOS' rights in such derivatives will be limited to the Japanese
language versions only, and KAINOS will not have the right to translate such
derivatives into any other language.

      3.2   KAINOS Developed Materials.  KAINOS may, at its own expense, adopt
its own trademarks, artwork, copy and packaging in marketing and promoting the
Japanese language versions of the Products and the derivatives of the Products
in the Japanese language produced by KAINOS.  KAINOS will not have the right to
use any of the trademarks or tradenames of ADAM on or with respect to the
Japanese language versions of the Products or derivatives of the Products in the
Japanese language produced by KAINOS.  Any copies of the English language



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versions of the Products distributed by KAINOS in Japan must be distributed and
sold in the original packaging furnished by ADAM; such copies may not be
repackaged by KAINOS without authorization from ADAM.


                                    Section 4
                                CONFIDENTIALITY

      4.1   Confidential Information.  All documentation and information
designated by the party disclosing the information (the "Disclosing Party") as
proprietary or confidential, including without limitation drawings, source code,
computer program listings, techniques, algorithms, and processes and technical
and marketing information ("Confidential Information") which is supplied by the
Disclosing Party in connection with this Agreement shall be treated
confidentially by the recipient of the confidential information ("Recipient")
and its employees and contractors and shall not be disclosed by the Recipient,
except as required in order to exercise the rights and obligations set forth in
this Agreement, without the Disclosing Party's prior written consent.  
Recipients of Confidential Information shall disclose Confidential Information
only to employees, contractors, and sublicensees who have a need to know and
have executed written agreements requiring them to comply with the nondisclosure
obligations set forth herein.

      4.2   Limitations.  Information shall not be considered to be Confidential
Information if it (1) is already or otherwise becomes publicly known through no
act of Recipient; or (2) is lawfully received from third parties subject to no
restriction of confidentiality; or (3) can be shown by Recipient to have been
independently developed by it; or (4) is authorized by the Disclosing Party to
disclose, copy or use; or (5) is disclosed by the Disclosing Party to third
parties without restriction on subsequent disclosure; or (6) is required to be
disclosed in the context of an administrative or judicial proceeding.

      4.3   Survival.  The provisions of this Section will survive the
termination of this Agreement for so long as the materials remain confidential
and proprietary, in the case of any materials which constitute trade secrets
under applicable law.  The duty of confidentiality with respect to all other
confidential information shall survive the termination or expiration of the
Agreement for a period of three (3) years.


                                    Section 5
                    WARRANTIES, COVENANTS AND INDEMNIFICATION

      5.1   Warranties and Covenants of ADAM.  ADAM represents, warrants and
covenants to KAINOS that:  (a) ADAM has the full power to enter into this
Agreement; (b) ADAM's performance of the terms of this Agreement and of ADAM's
obligations hereunder will not breach any separate agreement by which ADAM is
bound; (c) ADAM has retained (that is, it has not transferred or licensed) any
of the rights that it acquired in the Products; (d) the rights being granted to
KAINOS include all of ADAM's rights in and to the current localized Japanese
versions and derivatives of & Products developed during the period when Mosby
Consumer Health owned the rights in the Products; (e) other than Mindscape, ADAM
has not


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authorized or licensed, nor will it authorize or license, any party to
distribute English language versions of the Products in Japan; and (f) ADAM will
not make any derivative versions of the Products with the intent to be and/or
would be competitive with KAINOS in the Japanese market.  ADAM specifically
disclaims any warranty or covenant with respect to the noninfringement by the
Products or Trademarks of any third party intellectual property rights
(including any copyright rights, patent rights, trade secret rights or trademark
rights), and KAINOS expressly assumes any and all risk that the Products or the
Trademarks may infringe third party rights, except that KAINOS does not assume
any risks with respect to copies of Products distributed by Mindscape in Japan.
ADAM does not have actual knowledge of any existing claim against ADAM which
would affect ADAM's ownership rights to the Products.  ADAM agrees that it will
notify KAINOS if ADAM learns of any claim that would affect ADAM's ownership
rights to the Products, or any claim that the Products infringe any third party
rights in Japan, that may arise subsequent to the execution of this Agreement.

      5.2   ADAM's Indemnity.  A.D.A.M. agrees to indemnify, hold harmless and
defend KAINOS from all claims, defense costs (including reasonable attorneys'
fees), judgements and other expenses arising out of or on account of (a) the
breach of any representation, covenant or warranty set forth in Section 5.1
above; and/or (b) claims arising out of prior agreements involving MCH, Mosby,
AMI Inc., AMI-US, AMI-Japan (not related to claims covered under Section 5.5(c)
and (d) of this Agreement).

      5.3   KAINOS Obligation.  KAINOS shall notify A.D.A.M. promptly of any
claim as to which indemnification will be sought and provide A.D.A.M. reasonable
cooperation in the defense and settlement thereof.

      5.4   Warranties and Covenants of KAINOS.  KAINOS represents, warrants and
covenants to ADAM that: (a) KAINOS has the full power and authority to enter
into this Agreement and to fulfill its obligations hereunder; (b) any
promotional materials, packaging, documentation or other materials developed by
KAINOS for use with the Products, do not infringe upon, or misappropriate, any
copyright, trademark, trade secret or other proprietary rights of any third
party; (c) KAINOS's performance of the terms of this Agreement and of KAINOS's
obligations hereunder will not breach any separate agreement by which KAINOS is
bound; and (d) KAINOS has acquired all rights of AMI-Japan, Inc., a Japanese
corporation ("AMI-Japan") with respect to the Products, including without
limitation, the rights of AMI-Japan under the Standard Company Agreement between
Applied Medical Informatics, Inc. and AMI-Japan, Inc., dated February 19, 1996
(the "Company Agreement") and Statement of Work No. 1 ("Localization of Medical
HouseCall and Pediatric HouseCall for Japanese marketplace Effective on March
1, 1996") (the "Statement of Work"), and, as a result of such acquisition of
AMI-Japan's rights by KAINOS, AMI-Japan no longer has any right, title or
interest in or to the Products.

      5.5   KAINOS Indemnity.  KAINOS agrees to indemnify, hold harmless and
defend ADAM from all claims, defense costs (including reasonable attorneys'
fees), judgements and other expenses arising out of or on account of claims of:

            (a)   any actions or omissions on the part of KAINOS in 
      manufacturing, distributing, marketing, or sublicensing the Products;



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            (b)   any statements, claims, representations or warranties made by
      KAINOS or its employees, agents, sublicensees representative, relating to
      the Products;

            (c)   the breach of any representation, covenant or warranty set
      forth in Section 5A above;

            (d)   any claim by AMI-Japan against ADAM or KAINOS arising out of 
      or relating to the execution, delivery or performance of this Agreement or
      the Company Agreement or Statement of Work.

  5.6     A.D.A.M.'s Obligation. ADAM shall notify KAINOS promptly of any claim
as to which indemnification will be sought and provide KAINOS reasonable
cooperation in the defense and settlement thereof.


                                    Section 6
                                    ROYALTIES

      6.1   License Fees.  In consideration for the rights granted KAINOS under
Section 1 of this Agreement, and the Deliverables provided in Section 2.6,
KAINOS will pay to ADAM license fees in the aggregate amount of U.S.$750,000.00
(the "License Fees").

      6.2   Payment of License Fees.  The initial installment of the License 
Fees, in the amount of U.S.$375,000, will be payable upon execution of this
Agreement and the receipt by KAINOS of the Deliverables as stated in Section
2.6, by wire transfer of that amount, in U.S. Dollars, to the account of ADAM
designated in writing by ADAM.  The remaining balance of the License Fees,
U.S.$375,000, will be secured by KAINOS by a Letter of Credit in the amount of
US. $ 375,000 which ADAM would have the right to draw on March 31st, 1999
provided that (1) KAINOS had received the Deliverables in Section 2.6, and (2)
ADAM had provided any updates, revisions, enhancements or fixes that may exist,
and has provided any required support needed to complete the Japanese versions
of the Products, in each case as contemplated under Section 2.2 of this
Agreement.  All such payments will be made by wire transfer of US. Dollars to
the account of ADAM designated in writing by ADAM.

      6.3   No Offsets.  Except as may be required under the Conventions between
the United States of America and Japan governing Taxes on Income, the License
Pees due to ADAM under this Agreement are net amounts, exclusive of all taxes
(other than any required withholding of any US. corporate income taxes of ADAM
required by existing reciprocal tax agreements between the U.S. and Japan
governing such transactions), and are not subject to offset or reduction because
of any costs, expenses, or liabilities incurred by KAINOS or imposed on ADAM in
the performance of this Agreement or otherwise due as a result of this 
Agreement.



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      6.4   Taxes.  KAINOS will be responsible for, and will pay directly, any
and all taxes, duties and charges incurred in the performance of this Agreement,
including without limitation sales and use taxes, withholding taxes, duties and
charges imposed by federal, state or local governmental authorities in the
United States, Japan or elsewhere, but excluding U.S. corporate income taxes of
ADAM.  KAINOS will also be responsible for payment of any license fee,
assessment, duty, tax, levy, or other charge imposed by or in Japan as a result
of this Agreement or the transactions provided for under this Agreement.


                                    Section 7
                              TERM AND TERMINATION

      7.1   Term.  The term of this Agreement will commence on January 1, 1998
and will expire on December 31, 2097 (the "Initial Term"), unless earlier
terminated.

      7.2   Option to Renew.  At the end of the Initial Term, KAINOS will have
the option to extend the term of this Agreement automatically for an additional
term of 99 years, beginning on January 1, 2098, on the same terms and conditions
of this Agreement, other than the payment of License Fees.  At the time of such
exercise, KAINOS will pay license fees for the additional term in the amount of
U.S.$10.00.  All other terms and conditions of this Agreement will apply during
the extended term.  KAINOS will notify ADAM in writing whether KAINOS intends
not to exercise the option provided for in this Section 7.2 at least 90 days
prior to the end of the Initial Term.

      7.3   Termination.  This Agreement may be terminated on the sixtieth (60)
day after either party gives the other party written notice of a material breach
by the other party of any material term or condition of this Agreement, unless
the breach is cured prior to the end of the 60 day period (or, if the breach
cannot reasonably be cured within 60 days but can be cured within a reasonable
additional period of time, if the breach is not cured within such reasonable
additional period of time).  In addition, either party may terminate this
Agreement upon written notice to the other party if the other party (1)
dissolves or winds up its business (except in connection with a merger or
acquisition transaction); or (2) is subject of a voluntary or involuntary filing
under the bankruptcy laws of any jurisdiction, unless the filing is discharged
within 180 days.

      7.4   Rights in the Event of Dissolution, Insolvency or Bankruptcy.  If
either party is adjudicated as bankrupt or insolvent, or if the shareholders of
party shall resolve to dissolve and liquidate the party, and the other party at
the time of such adjudication or resolution is in full compliance with this
Agreement and has not been notified by the other party of default under the
terms of this Agreement, then the other party shall have right of access to all
source codes, diagrams and charts that may exist and are necessary to continue
the support, manufacture and marketing of the Japanese language versions of the
Products, and derivatives of the Products in the Japanese language, within the
Territory.


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                                    Section 8
                         DISTRIBUTION AFTER TERMINATION

      KAINOS and any of its sublicensees granted rights under this Agreement
will be entitled to continue to distribute and sell Products manufactured prior
to the date of termination pursuant to the terms of this Agreement
notwithstanding termination of the licenses granted in Section 1, for a period
not to exceed three (3) months.  However, KAINOS must not manufacture or
reproduce Products after the termination of the licenses granted in Section 1.1
and no sublicensee may manufacture or reproduce Products after the termination
of the license granted to KAINOS.


                                    Section 9
                               LEGAL PROCEEDINGS

      KAINOS will promptly notify A.D.A.M. of any infringement of A.D.A.M.'s
proprietary rights that comes to KAINOS's attention and will cooperate with
A.D.A.M. in any action brought by A.D.A.M. to investigate or remedy any such
infringement of these rights.


                                   Section 10
                      GOVERNING LAW AND DISPUTE RESOLUTION

      10.1  Attorneys' Fees.  If either party commences legal action to enforce
the terms of this Agreement, or should litigation occur between KAINOS and ADAM
over any other issue, then the prevailing party in such legal action shall
recover from the non-prevailing party all reasonable costs and expenses
incurred, including reasonable attorney fees and court costs. Court costs shall
mean all reasonable expenses incurred related to the litigation whether or not
such costs are taxable under applicable statutes.

      10.2  Governing Law.  The validity, construction, and performance of this
Agreement shall be governed by the laws of the State of New York without regard
to principles of conflicts of law.


                                   Section 11
                            MISCELLANEOUS PROVISIONS

      11.1  Notices.  For the purposes of all notices and other communications
required or permitted to be given hereunder, the addresses of the parties hereto
shall be indicated below. All such communications shall be in writing and shall
be deemed to have been duly given if sent by facsimile, the receipt of which is
confirmed by return facsimile, or if delivered personally with receipt
acknowledged, or sent by first class registered or certified mail or equivalent,
return receipt requested, if available, postage paid, or commercial carrier
(e.g. Federal Express or UPS), addressed to the parties at their addresses
respectively set forth below:


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            If to ADAM              A.D.A.M. Software Inc.
                                    1600 RiverEdge Parkway - Suite 800
                                    Atlanta, Georgia 30328
                                    Attention:  Robert S. Cramer, Jr.



            If to KAINOS:           Kainos Laboratories, Inc.
                                    38-18, Hongo 2-Chome
                                    Bunkyo-ku, Tokyo 113
                                    Japan
                                    Attn:  Mr. Toshimichi Nakamura

      11.2  Entire Agreement.  This Agreement, including any attached schedules,
constitutes the entire agreement between the parties with respect to the
services and all other subject matter hereof and merges all prior and
contemporaneous oral or written communications, agreements, representations
and/or understandings.  It shall not be modified nor any provision waived or
departed from except by a written agreement dated subsequent to the date of this
Agreement and signed on behalf of the parties by their respective duly
authorized representatives; and then such waiver or consent shall be effective
only in the specific instances of and for the specific purposes given.

      11.3  Severability.  In the event that any one or more of the provisions
of this Agreement is found to be illegal or unenforceable, then notwithstanding
such illegality or unenforceability, this Agreement shall remain in full force
and effect, and such term or provision shall be deemed modified as necessary to
achieve the original intent of the parties with respect to the Agreement.

      11.4  Contract Assignment. Neither party may assign their rights and
duties under this Agreement without the consent of the other party, which will
not be unreasonably withheld; however, either party may assign this Agreement to
any parent, subsidiary, or affiliate of such party or to any third party which
succeeds by operation of law to, or purchases or otherwise acquires
substantially all of the assets of such party or a subsidiary or affiliate of
such party and which assumes such party's obligations hereunder, provided,
further, that in no event shall the rights or obligations of either party
hereunder be assigned or assignable by any bankruptcy proceedings, and in no
event shall this Agreement or any rights or privileges hereunder be an asset of
either party under any bankruptcy, insolvency or reorganization proceedings.  
The rights and duties of each party will survive any permitted assignment by
either party.

      11.5  Waivers and Amendments.  No waiver, amendment, or modification of
any provision of this Agreement shall be effective unless consented to by both
parties in writing.  No



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failure or delay by either party in exercising any rights, powers, or remedy
under this Agreement shall operate as a waiver of any such right, power, or
remedy.

      11.6  Agency.  The parties are separate and independent legal entities.
Nothing in this Agreement shall constitute a partnership nor make either party
the agent or representative of the other.  Neither party has the authority to
bind the other or to incur liability on behalf of the other, nor to direct the
employees of the other.

      11.7  Titles and Headings.  The titles and headings of each section are
intended for convenience only and shall not be used in construing or
interpreting the meaning of any particular clause or section.

      11.8  Contractual Interpretation.  Ambiguities, inconsistencies, or
conflicts in this Agreement shall not be strictly construed against the drafter
of the language but will be resolved by applying the most reasonable
interpretation under the circumstances, giving full consideration to the
parties' intentions at the time this Agreement is entered into.

      11.9  No Third Party Rights.  This Agreement is not for the benefit of any
third party, and shall not be considered to grant any right or remedy to any
third party whether or not referred to in this Agreement.

      11.10  Authority.  A.D.A.M. and its representative executing this 
Agreement represent and warrant that such representative has the actual
authority to enter into this Agreement on behalf of and to bind A.D.A.M.
thereby.  KAINOS and its representative executing this Agreement represent and
warrant that such representative has the actual authority to enter into this
Agreement on behalf of and to bind KAINOS thereby.

      11.11 Confidentiality of Agreement.  The parties consider the terms of
this Agreement to be confidential. Neither party will disclose this Agreement or
its terms to any third party except (1) to the extent, if any, required by law
or to by the legal, accounting, investment, or banking requirements of a party;
or (2) with the prior written consent of the other party (such consent not to be
unreasonably withheld).

      11.12  LIMITATION ON LIABILITY; REMEDIES.  NEITHER PARTY SHALL BE LIABLE
TO THE OTHER PARTY FOR ANY INCIDENTAL, CONSEQUENTIAL, SPECIAL, OR PUNITIVE
DAMAGES OF ANY KIND OR NATURE, INCLUDING, WITHOUT LIMITATION, THE BREACH OF THIS
AGREEMENT OR ANY TERMINATION OF THIS AGREEMENT, WHETHER SUCH LIABILITY IS
ASSERTED ON THE BASIS OF CONTRACT, TORT (INCLUDING NEGLIGENCE OR STRICT
LIABILITY), OR OTHERWISE, EVEN IF EITHER PARTY HAS WARNED OR BEEN WARNED OF THE
POSSIBILITY OF ANY SUCH LOSS OR DAMAGE.  MOREOVER, IN NO EVENT SHALL EITHER
PARTY'S LIABILITY TO THE OTHER


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PARTY OR ANY THIRD PARTY EXCEED THE AMOUNT OF LICENSE FEES PAID TO ADAM AS
PROVIDED UNDER THIS AGREEMENT.

      11.13  Survival.  The following provisions will survive the termination or
expiration of this Agreement Sections 2.5, 3.1, 4, 5, 6, 8, 10, 11.11, 11.12, 
and this 11.13.

      11.14  Counterparts.  This Agreement may be executed in counterparts, and
a facsimile copy of this Agreement, signed by either party and transmitted to
the other party, will constitute a binding signature to this Agreement.

      11.15  Definitions.  The following definitions shall apply throughout this
Agreement:

            (a)   Collateral Materials.  "Collateral Materials" means the
      instruction manuals (user guide), packaging, labels, promotional and
      advertising materials which are or have been developed for use in the sale
      and promotion of the Products.

            (b)   Products.  "Products" means the three computer products known
      as "Medical HouseCall", "Pediatric HouseCall" and "Illiad", together with
      associated Collateral Materials.

            (c)   Trademarks.  "Trademarks" means any trademarks, service marks
      or tradenames of A.D.A.M. associated with the Products, as designated by
      A.D.A.M.

            (d)   Territory.  "Territory" means anywhere in the world.

      11.16  Bankruptcy or Insolvency.  This Agreement will survive any 
bankruptcy or insolvency of ADAM, and KAINOS will have the right under U.S.
bankruptcy law to elect to continue its licenses hereunder in accordance with
Section 365(n) of the United States Bankruptcy Code.

IN WITNESS WHEREOF, this Agreement is executed as of the Effective Date set
forth above.


A.D.A.M. SOFTWARE, INC.                   KAINOS LABORATORIES, INC.



By: /s/ Robert S. Cramer, Jr.             By:   /s/ Masanori Hirakawa
   --------------------------                   --------------------------


Its: Chairman and CEO                           
    -------------------------                   --------------------------


                                          ITS:  President
                                                --------------------------



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<PAGE>   13


                                    EXHIBIT A


Deliverables of A.D.A.M. to Kainos


1.    Medical Housecall, Pediatric Housecall, Iliad Product
      Windows and Macintosh Source Code (CD-ROM)


2.    Applied Medical Informatics Encyclopedia Processes & Tools (document)

3.    Applied Medical Informatics Knowledge Engineering Processes (document)

4.    Translation Process (document)

ADAM will provide, upon execution of this Agreement, KAINOS all object code,
source code, related technical materials in ADAM's possession relating to the
development of the current versions of the Products, in electronic form, as
listed on EXHIBIT A. ("Deliverables")

ADAM will also use its commercially reasonable efforts to furnish KAINOS with
access to any technical materials or information about the Products that is in
ADAM's possession and control (including using reasonable efforts to obtain such
materials or information from third parties) and would be useful to KAINOS in
the development and manufacture of the Japanese language versions of the
Products (including modifications of the Products developed by KAINOS).


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