Federal Register / Vol. 58, No. 135 / Friday, July 16, 1993 / Notices

ENVIRONMENTAL PROTECTION

AGENCY

[OPPTS-41039; FRL-4630-21

Thirty-Second Report of the TSCA

Interagency Testing Committee to the

Administrator; Receipt of Report,

Request for Comments, Notice of

Opportunity to Initiate Negotiations for

TSCA Section 4 Testing Consent

Agreements

AGENCY: Environmental Protection

Agency (EPA).

ACTION: Notice.

SUMMARY: The TSCA Interagency

Testing Committee (ITC), established

under section 4(e) of the Toxic

Substances Control Act (TSCA),

transmitted its Thirty-Second Report to

the Administrator of EPA on June 2,

1993. This report is included with this

notice. As noted in this Report, the ITC

revised the Priority Testing List by

adding one group of 34 chemicals to the

list for priority consideration by the

EPA Administrator for promulgation of

test rules under section 4(a) of the Act.

These chemicals are designated for

response within 12 months. Therefore,

in response to the ITC's designation,

EPA will either initiate rulemaking

under section 4(a) of TSCA, enter into

a testing consent agreement, or publish

a Federal Register notice explaining the

reasons for not initiating such

rulemaking within 12 months. The ITC

is also removing four designated

chemicals and two recommended

chemicals and eight recommended

chemical groups added in the TwentyEighth Report. The ITC's reasons for

removing these chemicals and chemical

groups are stated in the Thirty-Second

Report. There are no recommended with

intent-to-designate chemicals or

chemical groups in the Thirty-Second

Report. EPA invites interested persons

to submit written comments on the

Report.

In addition, EPA is soliciting

interested parties for participation in or

monitoring of a consent agreement

process for the chemicals that were

designated for dermal absorption

testing. EPA is also inviting

manufacturers and/or processors of

chemical substances who wish to

particijate in testing negotiations for the

chemicals designated for dermal

absorption testing to develop and

submit testing consent agreement

proposals to EPA.

DATES: Written comments on the ThirtySecond ITC Report must be received by

August 16, 1993. Written testing

proposals must be received by

September 14, 1993. Written notice of

interest in being designated an

"interested party" to the development

or monitoring of a consent agreement for

the chemicals designated for dermal

absorption testing must be received by

September 14, 1993. Those submitting

written testing proposals will be

considered "interested parties" and do

not have to submit separate written

notice. EPA will contact all "interested

parties" and advise them of meeting

dates.

ADDRESSES: Send six copies of written

submissions to: TSCA Docket Receipts

(TS-790), Office of Pollution Prevention

and Toxics, Environmental Protection

Agency. Rm. ET G-102,401 M St., SW.,

Washington, DC 20460. Submissions

should bear the document control

number (OPPTS-41039; FRL-4630-2).

The public record supporting this

action, including comments, is available

for public inspection in Rn. ET G-102

at the address noted above from 8 a.m.

to noon and 1 p.m. to 4 p.m., Monday

through Friday, except legal holidays.

FOR FURTHER INFORMATION CONTACT:

Susan B. Hazen, Director,

Environmental Assistance Division (TS799), Office of Pollution Prevention and

Toxics, Environmental Protection

Agency. 401 M Street, SW., Rm. E543B, Washington, DC 20460, (202)

554-1404, TDD (202) 554-0551.

SUPPLEMENTARY INFORMATION:

Electronic Availability. This document,

along with the Priority Testing List

revised according to the Thirty-Second

Report, is available as an electronic file

on The Federal Bulletin Board at 9 a.m.

on the date of publication in the Federal

Register. By modem dial 202-512-1387

or call 202-512-1530 for disks or paper

copies. This file is also available in

Postscript, Wordperfect and ASCII. The

Priority Testing List is available in

Wordperfect and ASCII.

I. Background

TSCA ( 15 U.S.C. 2601 et seq.)

authorizes the Administrator of EPA to

promulgate regulations under section

4(a) requiring testing of chemical

substances and mixtures ("chemicals")

in order to develop data relevant to

determining whether such chemicals

may present unreasonable risks to

health or the environment. Section 4(e)

of TSCA established the Interagency

Testing Committee (ITC) to recommend

chemicals and chemical groups to the

Administrator of EPA for priority testing

consideration. Section 4(e) directs the

ITC to revise the TSCA section 4(e)

Priority Testing List at least every 6

months. The most recent revisions to

this List are included in the ITC's

Thirty-Second Report. The Report was

received by the Administrator on June 2,

1993, and is included with this notice.

The Report adds I group of 34

chemicals to the TSCA section 4(e)

Priority Testing List and removes 4

designated chemicals and 2

recommended chemicals and 8

chemical groups added in the TwentyEighth Report.

I. Written and Oral Comments on

Recommendations

EPA invites interested persons to

submit detailed comments on the ITC's

new recommendations. The Agency is

interested in receiving information

concerning additional or ongoing health

and safety studies on the subject

chemicals as well as information

relating to the human and

environmental exposure to these

chemicals.

A notice will be published at a later

date in the Federal Register adding the

substances recommended in the ITC's

Thirty-Second Report to the TSCA

section 8(d) Health and Safety Data

Reporting Rule (40 CFR part 716), which

requires the reporting of unpublished

health and safety studies on the listed

chemicals. That notice will also add the

chemicals to the TSCA section 8(a)

Preliminary Assessment Information

Rule (40 CFR part 712). The section 8(a)

rule requires the reporting of production

volume, use, exposure, and release

information on the listed chemicals.

I1. Status of List

The ITC's Thirty-Second Report notes

the addition of one chemical group to

the Priority Testing List and the removal

of 4 designated chemicals and 2

recommended chemicals and 8

chemical groups added in the TwentyEighth Report. The current TSCA

section 4(e) Priority Testing List

contains 18 chemicals and 17 chemical

groups; 2 chemical groups and 7

chemicals are designated for priority

testing consideration.

IV. Testing Consent Agreements 1. Solicitation of Interested Parties.

EPA's procedures for requiring the

testing of chemical substances under

section 4 of TSCA at 40 CFR 790.22,

includes the adoption of enforceable

consent agreements and the

promulgation of test rules. EPA has on

numerous occasions been approached

by chemical companies interested in

negotiating consent agreements for

testing ITC chemicals or chemical

groups. As a result of these requests,

EPA is now inviting persons interested

in participating in or monitoring

35490
Federal Regster / Vol. 58, No. 135 / Friday, July 16, 1993 / Notices

negotiations on the chemicals

designated in the Thirty-Second ITC

Report to notify EPA in writing. Those

who respond to this solicitation by the

deadline established in this notice will

have the status of "interested parties"

and will be afforded opportunities to

participate In the negotiation process. These "interested parties" will not incur

any obligations by being designated

"interested parties." This solicitation is

separate from the solicitation of

interested parties made in the Federal

Register of May 5, 1993 (58 FR 26898).

2. Solicitation of testing proposals for

consent agreement negotiations. EPA is

also now soliciting testing proposals for

a consent agreement to perform dermal

absorption testing on the 34 chemical

substances designated in the ThirtySecond Report. While this solicitation is

separate from the solication of

interested parties made for the 24

substances designated in the ThirtyFirst ITC Report published May 5, 1993

(58 FR 26898). EPA expects that any testing consent agreement adopted for

this effort, as well as the testing method

referenced, will be substantially similar.

Following publication of this notice,

manufacturers and/or processors have

60 days to develop and submit testing

proposals for any of the chemical

substances designated in the ThirtySecond Report that they wish EPA to

consider as candidates for consent

agreement negotiations. Federal scientists from a number of

the ITC's statutory and liaison

organizations including the Consumer

Product Safety Commission,

Environmental Protection Agency, Food

and Drug Administration. National

Institute for Occupational Safety and

Health, and Occupational Safety and

Health Administration, have developed

a proposed test protocol that will

provide data needed by several U. S.

Government Organizations represented

on the ITC. This proposed protocol is

entitled "Protocol for in vitro

Percutaneous Absorption Studies" and

is available to the public through the

TSCA Docket Receipts and the

Environmental Assistance Division

listed above. This document should be

reviewed before submitting any testing

proposals in response to this notice.

For additional technical information

on this testing protocol contact Dr. John

D. Walker, Executive Director, TSCA

Interagency Testing Committee, (202)

260-1820.

All testing proposals submitted

should describe the testing to be

performed and explain any deviations

from the test protocol that are necessary

to assure the development of reliable

percutaneous absorption data.

EPA will review the submissions and

select the most promising submissions

as candidates for negotiation.

Submissions that fully address the ITC's

concerns will have a higher chance of

success than those that do not fully

address all data needs.

3. Negotiation of testing program and

development of a testing consent

agreement. EPA will follow the

negotiation procedures under 40 CFR

790.22, and to the extent feasible, the

timetable outlined in 40 CFR part 790,

Appendix A to subpart B.

In the case of the 34 substances

designated for priority testing

consideration in the Thirty-Second ITC

Report, EPA believes that obtaining

testing through the development of

.consent agreements would be most

feasible if interested manufacturers

organized a testing consortium. Because

of the straightforward and relatively

ipexpensive nature of the tests for each

of the substances (i.e., dermal

absorption tests), and the costs to EPA

and industry that would be incurred

should many consent agreements be

pursued, EPA believes that negotiating

with an organized group of

manufacturers may be the most efficient

means to obtain the needed testing. For additional information about

process or negotiations contact Frank

Kover, Chief, Chemical Testing and

Information Branch, (202) 260-8130.

Authority: 15 U.S.C. 2603.

Dated: July 8, 1993.

Charles M. Auer,

Director Chemical Control Division, Office of Pollution Prevention and Toxics.

Thirty-Second Report of the TSCA

Interagency Testing Committee to the

Administrator, Environmental

Protection Agency

SUMMARY. The TSCA Interagency

Testing Committee (ITC) was created

under section 4(e) of the Toxic

Substances Control Act (TSCA) as an

independent advisory committee to

establish testing priorities for TSCAregulable chemical substances and

mixtures ("chemicals") for the

Administrator of the U.S.

Environmental Protection Agency (EPA). The ITC maintains the TSCA

Section 4(e) Priority Testing List and

transmits revisions of the List as a

Report to the EPA Administrator at least

every 6 months for action and

publication in the Federal Register.

This Report presents the ITC's revisions

of the Priority Testing List resulting from

its deliberations during the reporting

period November, 1992 through May,

1993.

In this revision, ITC is designating a

group of 34 chemicals of regulatory

interest to the Occupational Safety and

Health Administration (OSHA) for

dermal absorption testing and is

removing 4 designated chemicals, 2

recommended chemicals and 8

recommended chemical groups added

in ITC's 28th Report (56 FR 41217,

August 19, 1991). These revisions are

summarized in Table 1.

TABLE 1.- REVISIONS TO THE TSCA SECTION 4(E) PRIORITY TESTING LIST

Action Chemicals or Groups Date

Designated for dermal absorption testing ............. ..............

Previously Designated Chemicals Removed from the Ust ...........................................

34 OSHA Chemicals with Insufficient dermal absorption data.

n-Butanol .................................................................

Isobutanol ..............................................

Dim ethyl terephthalate ............................................ Di(2-ethyIhexyi)adIpate ...........................................

38491
Federal Register / Vol. 58, No. 135 / Friday, July 16, 1993 / Notices

TABLE 1.- REVISIONS TO THE TSCA SECTION 4(E) PRIORITY TESTING LIST-Continued

Action Chemicals or Groups Date

Previously Recommended Chemicals Removed from the UI t ..................................... Aliyl alcohol ............................................................. 5193

2,4-Dichlorophenol .................................................

Previously Recommended Chemical Groups Removed from the List .............. Alkynes .................................................................. 5193

Nitroalcohols ....................................................

Phosphonlums ........................................................ Hydrazines ..............................................................

Oxlrane .................................................................. Alkoxysllanes ..........................................................

Aldehyde hydrates ............................... isothlocyanates

1.1 Background. Since its creation in

1976 under section 4(e) of the Toxic

Substances Control Act (Public Law 94-

469, 90 Stat. 2003 et seq., 15 U.S.C. 2601

et seq.), the TSCA Interagency Testing

Committee has submitted 31 semiannual Reports to the Administrator of

the U.S. Environmental Protection

Agency to establish testing priorities for

TSCA-regulable chemicals. These

Reports have been published in the

Federal Register and are also available

from the ITC. In this, its 32nd Report,

the ITC is revising its Priority Testing

List by designating a group of 34

chemicals for dermal absorption testing

and by removing 4 designated

chemicals, 2 recommended chemicals

and 8 recommended chemical groups. A

short version of the Priority Testing List

appears at the end of this Report. The

32nd Report and the complete Priority

Testing List with all individual

chemicals in each group are available

upon request from the ITC (address and

phone number given at the end of this

Report) or the Government Printing

Office (202/512-1530) and on the

Federal Bulletin Board by modem (202/

512-1387).

The ITC meets at least once a month

and produces its Reports with the help

of staff and technical contract support

provided by EPA. ITC membership and

support personnel are listed at the end

of this Report.

Following receipt of the ITC's

Reports, the EPA's Office of Pollution

Prevention and Toxics promulgates

TSCA section 8(a) and 8(d) rules that

require manufacturers, processors and

distributors to submit (1) production

and exposure data and (2) health and

safety studies within 2 months of the

rules' effective dates These submissions

are indexed and stored by EPAtand

reviewed by the ITC. Within 12 months

of an ITC designation, the Administrator

of EPA must initiate a proceeding under

TSCA section 4(a) to implement the

ITC's testing-recommendations or

publish in the Federal Register the

Administrator's reasons for not

initiating action.

1.2. Actions taken by the ITC in this

Report-i .2.a Designated chemicals.

Thirty-four OSHA-nominated chemicals

for which available dermal toxicity or

absorption data are insufficient,

I. Rationale for the Designation

OSHA previously established

Permissible Exposure Limits (PELs) for

chemical substances and mixtures to

limit workers' exposure to industrial

chemicals. In general, PELs are based on

inhalation of airborne dusts and vapors.

In those cases where chemical

absorption through the skin could be

harmful, the chemicals with PELs are

assigned skin notations. OSHA needs

quantitative measures of dermal

absorption to evaluate potential hazards

to workers. OSHA requested that the

ITC use its TSCA section 4(e) statutory

authority to designate chemicals with

PELs for priority testing consideration

by the EPA Administrator. In its 31st

Report, the ITC designated for dermal

absorption testing a group of 24 chemicals for which no dermal toxicity

or absorption data could be located in

the publicly available literature. In this

Report, the ITC is designating a group of

34 chemicals for dermal absorption . testing because existing dermal toxicity

or absorption data are not sufficient for

OSHA's needs (Table 2). mDinitrobenzene is already on the Priority

Testing List as a recommendation from

the 28th Report and is being designated

in this Report for dermal absorption

testing.

TABLE 2.- OSHA CHEMICALS DESIGNATED FOR DERMAL ABSORPTION

TESTING

GAS No.__J Chemica Name

, 61-82-5 Amitrole'

74-96-4

75-15-0

75-25-2

75-34-3

77-78-1

Ethyl bromide

Carbon disulfide

Bromofonrn

1,1-Dichloroethane

Dimethyl sulfate

TABLE 2.- OSHA CHEMICALS DESIGNATED FOR DERMAL ABSORPTION

TESTING--Continued

CAS No. Chemical Name

79-46-9 2-Nitropropane

80-62-6 Methyl methacrylate

84-66-2 Diethyl phthalate

88-72-2 o-Nitrotoluene

89-72-5 o-sec-Butylphenol

90-04-0 o-Anisidine

95-13-6 Indene

95-49-8 o-Chlorotoluene

99-65-0 m-Dinltrobenzene

100-00-5 p-Nitrochlorobenzene

100-01-6 p-Nitroaniline

100-44-7 Benzyl chloride

100-63-0 Phenylhydrazine

106-49-0 p-Toluldine

108-44-1 m-Toluldine

108-90-7 Chlorobenzene

109-99-9 Tetrahydrofuran

121-14-2 2,4-Dinitrotoluene

122-39-4 Diphenylanine 126-99-8 beta-Chloroprene

150-76-6 p-Methoxypheno 528-29-0 o-Dlnitrobenzene

540-69-0 1,2-Dichloroethylene 625-17-5 m-Phthalodinitrile

768-52-5 N-Isopropyanillne

1300-73-8 Xylidine

6423-43-4 Propylene glycol dinitrate

25013-15-4 Vinyl toluene

I. Supporting Information

In its January 19, 1989 Air

Contaminants Rule (54 FR 2332), OSHA

stated that:

The purpose of having the skin designation

is to prevent the same toxic effects that the

chemical causes through inhalation. The

inhalation limit is based on keeping exposure

below the limit which will create a significant risk of material impairment of

health. If skin absorption is possible, an

employee might be below the Inhalation

limit; however, the additional body burden

through skin absorption may create the

material impairment which the limit

attempts to reduce.

In September 1991, OSHA nominated

chemical substances and mixtures with

PELs (54 FR 2332) to the ITC to assess

the availability of data relevant to

dermal absorption and the possibility of

38492
Federal Register / Vol. 58, No. 135 / Friday, July 16, 1993 / Notices

testing under TSCA. A summary of

TC's review of these OSHA chemicals

is presented in the following Figure 1:

Figure 1. Summary of ITC Review of OSHA Chemicals.

658 Chem"ca Substances and I Mixtures from 54FR2332 I

24 Chemicals with no dermal toxicity data 1 Designated In ITC's 31st Report

. 75 hemicals with some dermnal toxicity dataI

145 Chemicals that are polYmers,

pesticides, complex mixtures, or CFCs

The ITC initiated an evaluation of 658

of these chemicals and set aside for

future review 145 chemicals that are

polymers, pesticides, complex mixtures,

or chlorofluorocarbons (CFCs). For the

remaining 513 chemicals, the Registry of

Toxic Effects of Chemical Substances

(RTECS) was searched forreported

dermal LD50 values. Chemicals with

rabbit dermal LD50s in RTECS were

deferred for future ITC review.

Chemicals that are vapors at ambient

temperature, highly reactive, known to

have low toxicity, or members of OSHAdefined chemical groups were also

deferred for future ITC review. RTECS,

INDEX MEDICUS, MEDLINE, TOXLINE,

TOXUIT, TSCATS and EPA's Existing

Chemical Assessment Tracking System

were searched to determine If dermal

toxicity or absorption data were

available for the remaining 99

chemicals. No dermal toxicity or

absorption data were located for 24

chemicals. These 24 chemicals were

designated for dermal absorption testing

in the ITC's 31st Report.

441 Chemicals that are vapors, sensitizers, highly reactive,

members of OSHA-defined chemical

groups, or have known low toxicity

or dermal LD50 values

38491,
Federal Register / Vol. 58, No. 135 / Friday, July 16, 1993 / Notices

The literature searches located 168

references on dermal toxicity or

absorption data for 75 chemicals. The

lTC reviewed these references and made

a tentative determination that 14

chemicals had sufficient data to

estimate the dermal absorption rate.

These 14 chemicals were referred to

OSHA for further evaluation. The ITC

also determined that 27 chemicals had

dermal LD50 values or were sensitizers,

fast polymerizers, of known low

toxicity, or were members of OSHAdefined chemical groups. These 27 were

added to the 414 deferred above for

future ITC review. The ITC determined

that the remaining 34 chemicals had

insufficient data to estimate dermal

absorption rates and is therefore

designating these 34 chemicals for

dermal absorption testing in this Report. 2.2 Removal of Chemicals from the

Priority Testing List

I. Rationale for the Removals

In its 28th Report to the Administrator

(56 FR 41212), the ITC designated 6

chemicals and recommended 3

chemicals and 11 chemical groups. The

rationale for adding the individual

chemicals to the Priority Testing List

was that the resulting test data could be

used to increase the confidence in the

Reference Concentrations (RICs) and

Reference Doses (RiDs) for these

chemicals in EPA's Integrated Risk

Information System (IRIS). Eight of the

11 chemical groups were added to

provide EPA with data to develop and

improve Quantitative Structure Activity

Relationships (QSARs) for predicting

biodegradation and aquatic toxicity in

the review of new chemicals

structurally related to the recommended

groups of chemicals.

Last year EPA requested that the ITC

review its actions in the 28th Report in

light of the possibility of voluntary

testing of some of the designated

chemicals and the relevance of

additional data for QSARs compared to

other data needs. The Committee

reevaluated the designations and

recommendations of the 28th Report

and concluded that, while testing of

these chemicals and groups would

provide useful information to EPA and

others, the need for data is greater for

chemicals to which workers are exposed

and which pose a possible but unknown

hazard via skin absorption. In the 31st

Report, the ITC designated a substantial

number of these chemicals for which

there are no dermal toxicity data.

Further study of the "OSHA chemicals"

reveals that many more have

insufficient dermal absorption data.

Because earlier entries to the List and

present designations are competing for

-scarce resources at EPA and within the

1TC, the Committee has reevaluated

their relative priorities. The Committee

concluded that the previously

recommended chemicals are of lower

priority than those now being

designated.

II. Specific Actions

A. Removal of Four of the Six Chemicals

Designated in the 28th Report

In March, 1993, EPA received written

confirmation that industry will test 4 of

the 6 designated chemicals. Industry has

committed to develop dossiers and

necessary test data under the Screening

Information Data Set (SIDS) program of

the Organization for Economic

Cooperation and Development (OECD).

The SIDS program Is a consensus testing

regimen developed for screening high

production chemicals that is accepted

by all OECD member nations. The four

chemicals are n-butanol, isobutanol,

di(2-ethylhexyl)adipate, and dimethyl

terephthalate.

The ITC views the voluntary

commitments from industry to conduct

the SIDS testing as an important first

step in filling the existing data gaps of

these chemicals. Although not identical

to the tests called for by the ITC in its

28th Report, the SIDS testing addresses

the general concerns of the Committee

and will be useful to EPA for the RfCs

and RfDs. Therefore, in this Report, the

ITC is removing these four designated

chemicals from the Priority Testing List.

In. the event the SIDS information is not

developed or is deemed inadequate, the

ITC will reconsider designating these

chemicals in a future report. The other

2 designated chemicals, acetone and

thiophenol, remain on the List.

B. Removal of Two Chemicals and Eight

Chemical Groups Recommended in the

28th Report

As described above, the 28th Report

recommended 3 chemicals (allyl

alcohol; 2,4-dichlorophenol; and mdinitrobenzene) to obtain data for the

IRIS data base and 8 groups (aldehyde

hydrates, alkoxysilanes, alkynes,

hydrazines, isothiocyanates,

nitroalcohols, oxiranes, and

phosphoniums) to develop QSARs.

Submission of data on these chemicals

would take place after EPA issues

section 8(a) and 8(d) rules. EPA

requested section 8 information on the

chemicals added to the Priority Testing

List in the 27th Report to determine if

the submitted data will be useful to EPA

for its IRIS and QSAR activities. Until

the requested information is analyzed,

EPA questioned if more data are needed

for this purpose. Thus, EPA requested

the ITC to remove the recommended

chemicals and groups in the 28th Report

from the List.

Member agencies did not identify

priority concerns for 2 of the individual

chemicals or the groups and, in view of

competing priorities, the Committee is

removing 2 chemicals and 8 groups

from the List. The chemicals being

removed are allyl alcohol and 2,4-

dichlorophenol. Allyl alcohol is listed

in Title III of the 1990 Clean Air Act

amendments and is under study at EPA

for residual risk levels. The National

Toxicology Program has completed a

carcinogenicity study on 2,4-

dichlorophenol and this chemical is

also being considered for regulation by

EPA's Office of Drinking Water. The

following groups are removed: aldehyde

hydrates, alkoxysilanes, alkynes,

hydrazines, isothiocyanates,

nitroalcohols, oxiranes, and

phosphoniums.

The ITC plans to continue review of

the 8 removed groups on a chemical by

chemical basis to assess possible

concerns of Member agencies. Although

the individual chemicals and groups are

no longer on the Priority Testing List

and EPA will not be issuing requests for

information under TSCA section 8, all

interested persons are invited to submit

unpublished chemical fate or ecological

effects data for use in developing or

modifying QSARs. Submissions can be

made to EPA's Public Docket Office and

should bear document control number

OPTS-41035. The ITC will use all

submitted data in its continuing review.

THE TSCA SECTION 4(E) PRIORITY TESTING LIST

R- Date ChemIcal/roup Action

22 May 1988 Elhoxyfated quatemaiy ammonium oompounds ........ Recommended

22 May 1988 Imidazollum quaternary ammonium compounds Recommended

38494
Federal Register I Vol. 58, No. 135 I Friday, July 16, 1993 I Notices

THE TSCA SECTION 4(E) PRIORITY TESTING LiST--Continued

PortIII Re- Date ChmaVGroup Action

November 1988

November 1988

November 1988

November 1988

November 1988

November 1988

November 1989

May 1990

May .1990

May 1990

November 1990

November 1990

November 1990

November 1990

November 1990

November 1990

November 1990

November 1990

November 1990

November 1990

November 1990

May 1991

May 1991"

May 1991

May 1991

November 1991

November 1991

May 1992

May 1992

January, 1993

January 1993

January 1993

Tetrakls(2-chloroethyl)ethylene di-phosphate ....................

Tds(1,3-dichloro-2-propyl) phosphate ................................

Trts(1-chloro-2-propyl) phosphate ......................................

Tds(2-chloro-1-propyl) phosphate ....................

Tds(2-chloroethyl)- phosphate ...........................................

Butyraldehyde ....................................................................

Brominated flame retardants .............................................

Isocyanates............................

Brom lnated flam e retardants .............................................

Alkyl phosphates ........................................................

Acetophenone ..........................

Phenol ................... ; ...........................................................

N,N.Dlmethylaniline ...........................................................

Ethylacetate .......................................................................

2,6-Dim ethylphenol ............................................................

Aldehydes ..........................................................................

2,4-Dinttrophenol ..................................... , ..........................

3,4-Dlm ethylphenol ............................................................

N-phenyl-I-naphthylamine ................................... * .............

Sulfones .............................................................................

Substantially produced chemicals In need of sub-chronic

toxicity testing .................................................................

Acetone .... ................................

Thiophenol .........................................................................

m-Dinltrobenzene ...............................................................

Cyanoacrylates ...........................................................

W hite phosphorus ..............................................................

Alkyl-, bromo-, chloro-, hydroxymethyldiaryl ethers .........

SlIoxanes ............................................................................

Chloroalkyl phosphates ......................................................

OSHA chemicals with no dermal toxicity data ..................

Propylene glycol ethers and esters (revised) ....................

Methyl ethylene glycol ethers and esters (revised) ..........

Recommended with Intent-to-desIgnate

Recommended wIth Intent-to-designate

Recommended with Intent-to-designate

Recommended with Intent-to-desIgnate

Recommended with Intent-to-designate

Recommended

Recommended

Recommended with Intent-to-designate

Recommended

Recommended

Designated

Designated

Designated

Designated

Designated

Recommended with Intent-to-designate

Recommended

Recommended

Recommended

Recommended

Recommended

Designated

Designated

Recommended

Recommended

Recommended

Recommended

Recommended

Recommended

Designated

Recommended

Recommended

321 May 1993 OSHA chemicals with Insufficient dermal absorption data I Deslgated

TSCA INTERAGENCy TESTING COMMITTEE Statutory Organizations and Their Representatives.

Council on Environmental Quality ......................... : .....................................................................................

Department of Commerce ...................................... ....................................................................................

Environmental Protection Agency ...............................................................................................................

National Cancer Institute .............................................................................................................................

National Institute of Environmental Health Sciences ......................................

National Institute for Occupational Safety and Health ................................................................................

National Science Foundation.............................................

Occupational Safety and Health-Administration .........................................................................................

Liaison Organizations and Their Representatives.

Agency for Toxic Substances and Disease Registry .................................................................................

Charles Herrick, Member

Willie E. May, Member

Edward White, Alternate

James B. Willis, Member

John S. Leltzke, Alternate

Thomas P. Cameron, Member

Richard Adamson, Alternate

Errol Zelger, Member

Robert W. Mason, Member

Henryka Nagy, Alternate

Carter Klmsey, Member, Chair

Jarvis L. Moyers. Alternate

Christine Whittaker, Member, Vice

Chair

Surender Ahlr, Altemate

Sharunda Buchanan, Member

38495
Federal Register / Vol. 58, No. 135 / Friday, July 16, 1993 / Notices

TSCA INTERAGENCY TESTING COMMrrTEE--Continued

Consumer Product Safety Comm ission ......................................................................................................

Department of Agdculture .................................................................................................................

Department of Defense ......................................................................................................................

Departm ent of the Interior .................................................................................................................

Food and Drug Adm inistation ....................................................................................................................

National Library of Medicine .......................................................................................................................

National To logy Program .....................................................................................................................

Couns l ..................................................................................................o,.............................. .......

Technical Support Contractor .....................................................................................................................

ITC Staff ......................................................................................................................................................

Val Schaeffer, Member

Lakshml C. Mishra, Alternate

Donald Derr, Member

Cliff Rice, Alternate

Randall S. Wentsel, Member

Jim Petty, Member

Barnett A. Rattner, Alternate

Edwin J. Matthews, Member

Raju Kammula, Alternate

Vera Hudson, Member

Victor A. Fung, Member

Mary Ellen Levine, Office of the

General Counsel, EPA

Syracuse Research Corporation

John D. Walker, Ph.D., M.P.H., Executive Director

Norma S.L. Williams, Executive Assistant

TSCA Interagency Testing Committee U.S. EPNVOPPT (TS-792) 401 M St.. SW., Washington,

D.C. 20460, (202) 260-1825

[FR Doc. 93-16895 Filed 7-15-93; 8:45 am]

- AO 141~ e

38496