### ey p United States Environmental Protection Agency , Washington, D.C. 20460

**DATA CALL -**  **IN RESPONSE** OMB Approval 2070 - 0174 INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information reques ted on this form. Use additional sheet(s) if necessary. 1. Company Name and Address 2. Case # and Name 223 Difenzoquat Active Ingredient # and n ame 106401 difenzoquat 3. Date and Type of DCI and Number GENERIC FFDCA DCI

Item 9, e nter the appropriate numerical response for each guideline study that you intend to support : 1 = Developing Data, 2 = Submitting an Existing Study, 3 = Upgrading a Study, 4 = Citing an Existing Study. (For 860.1500 or 860.1520, concerning a specific commodity, you may enter 5 = Will not support). 4. Guideline Requirement Number 5. Study title Footnotes to Data Requirements 6a. Protocol 6 b . Progress Reports 7. Test Substance 8. Time

Frame (Months) 9. Recipient

Response 1 2 3 860.1500 Crop Field Trial

– Wheat and barley

hay and wheat forage No TEP 24 870.6 2 00 Neurotoxicity Battery No TGAI 12 870.7800 Immunotoxicity Yes TGAI 12 10 . Certification : I certify that the statements made o n this form and all attachments are true, accurate, and complete. I acknowledge that any knowingly false or misleading statement may be punishable by fine, imprisonment or both under applicable law. Signature of Individual or Signature and Title of Company’s Authorized Representative ________________

_____ __ _________

__ ________ ___ 11. Date 12. Name of Company or Individual Contact (Include e - mail address) 13. Phone Number

**Failure to Submit the 90 -**  **Day Response :**  If a submission of a response to U.S. EPA to comply with the Data Call - In requirements of the final order is not submitted within 90 days after publication of the final order in the Federal Register, EPA may revoke the appropriate tolerance or tolerances a ssociated with the active ingredient named in Item 2. **90 -**  **Day Response Instructions:** It em 1, enter your company or individual name and address. It em 6a identifies any study protocol report timeframe, if required by the Agency. It em 6 b identifies study progress report timeframes, if required by the Agency. It em 7 identifies the code associated with the substance that must be used for testing :PAI = pure active ingredient, TGAI = technical grade active ingredient, EUP = end -use product, MP = manufacturi ng -use product, MET = metabolites, TEP = typical end -use product, PAI/M = pure active ingredient and metabolites, TEP/MET = typical end -use product and metabolites, DEGR = degradates, IMP = impurities, PAIRA = pure active ingredient radiolabeled, PAIRA/M = pure active ingredient radiolabeled and metabolites, PAIRA/PM = pure active ingredient radiolabeled and plant metabolites, TGAI/TEP = technical grade active ingredient or typical end -use product, PAI/PAIRA = pure active ingredient or pure active ingredient radiolabeled, MP/TGAI = manufacturing -use product and technical grade active ingredient, TGAI/PAIRA = technical active ingredient or pure active ingredient radiolabeled, TGAI/PAI = technical grade active ingredient or pure active ingredient, TEP/PAI/M = typical end -use product or pure active ingredient and metabolites . It em 8 identifies timeframe s for EPA’s re ceipt of data. Timeframes begin on the date of publication in the Federal Register of the final order for the Data Call - In. It em 9, enter the appropriate numerical response for each guideline study that you intend to support: 1 = Developing Data, 2 = Submitting an Existing Study ( that has not been submitted previously to EPA by anyone ) , 3 = Upgrading a Study ( classified by EPA as partially acceptabl e and upgradeable ) , 4 = Citing an Existing Study ( that EPA has classified as acceptable or an existing study that has been submitted but not reviewed by the Agency) . Note, for guidelines 860.1500 or 860.1520, concerning a specific commodity, you may enter 5 = Will not support . It em 10, sign the certification statement

– it must be signed by an authorized representative of your company and the person signing must include his/her title. It em 11, enter the date of signature. It em 12, enter the name of the person EPA should contact with questions regarding your response (Include e - mail address) . It em 13, enter the telephone number of your company contact. **Failure to Comp ly with Response Commitment and** **/or Data Requirements:** Events that may be the basis for revocation of tolerances associated with the active ingredient named in Item 2 include, but are not limited to the following: No person submits on the required schedule: (1) an acceptable proposed or final protocol when such is required to be submitte d to the Agency for review, (2) an adequate progress report on a study as required by the final order, (3) acceptable data as required by the final order, (4) s upportable certifications as to the conditions of submitted data, where required by the final order and where no other cited or submitted study meets the data requirements the study was intended to fulfill. 

### United States Environmental Protection Agency , Washington, D.C. 20460

**FOOTNOTES AND KEY DEFINITIONS FOR GUIDELINE REQUIREMENTS**

Case # and Name 0 223 Difenzoquat , GENERIC FFDCA DCI 

### OMB Approval 2070 - 0174 Footnotes: 870.7800 Immunotoxicity 1. A protocol must be submitted for Agency review prior to study initiation.