U.S. ENVIRONMENTAL PROTECTION AGENCY 

EPA PREMANUFACTURE 

NOTICE 

SUBSTANCES 

OFFICER 

OFFICE OF POLLUTION PREVENTION 

AND TOXIC SUBSTANCES, 7407 

U.S. E.P.A. 401 M STREET, SW 

W D.C, 20460 

Ul:;"~n..n,... INSTRUCTIONS 

pr' 

1\_ "". r"

O;~FT \..::,,.It 

• \I lOr .' In' :-;::' ~f'('''''' tr" < tl'~ .J' _.J 

........... iI>' I 


Company Sanitized 

• 	 You must provide all information requested in this form to the extent that it is known to or reasonably ascertainable by you. Make reasonable estimates if you do 

not have actual data, 

• 	 Before you complete this form, you should read the "Instructions Manual for Pre manufacture Notification" (the Instructions Manual is available from the Toxic 

Substances Control Act (TSCA) Information Service by calling 202·554·1404, or faxing 202·554.5603). 

If a user fee has been remitted for this notice (40 CFR 700,45), indicate in the boxes above the TS·user fee identification number you have generated, Remember, 

your user fee lD number must also appear on your corresponding fee remittance, which is sent to EPA, HQ Accounting Operations Branch (PM·226), PO 

360399M, Pittsburgh, PA 15251-6399, Attn, TSCA User fee, 

Part [-GENERAL INFORMATION 

You must provide the currently correct Chemical Abstracts (CA) Name ofthe new 

chemical substance, even if you claim the identity as confidential You may authorize 

another person to submit chemical identity information for you, but your submission will 

not be complete and the review will not begin until EPA receives this information, A 

letter in support ofyour submission should reference your TS user fee identification 

number, You must submit an original and two copies ofthis notice including all test data, 

Ifyou claimed any information as confidentia1, a single sanitized copy must also be 

submitted. 

Part ll-HUMAN EXPOSURE AND ENVIRONMENTAL RELEASE 

Ifthere are several manufacl:Ul'e, processing, or use operations to be described in Part II, 

sections A and B ofthis notice, reproduce the sections as needed. 

Part 111- UST OF ATTACHMENTS 

Attach additional sheets iftherc not enough space to answer a question fully. Label 

each continuation sheet with the ~nding sectiOIl beading, In Part ill, list these 

attachments, any test data or other data and any optional information included in the 

notice. 

OPTIONAL INFORMATION 

You may include any information that you Wllllt EPA to consider in evaluating the new 

substance, On page II ofthis form, space has been provided for you to des<:ribed 

pollution prevention and recycling information you may have regarding the new 

substance, 

So-called "binding" boxes are included throughout this form for you to indicate your 

willingness to be bound to certain statements you make in this section, such as use, 

production volume, protective equipment. ,. This Optioll is intended to reduce delays 

that routinely accompany the development of COQSel\( orden or Significant New Use 

Rules, Except in the case ofexemption applications (such as TMEA. LVB, LOREX) 

where certain information provided in SIICh notification is binding on the submitter when 

the Agency approves the exemption application, checking a binding box ill this notice 

by itself prohibit the submitter from later deviating from the information (except 

chemical identity) reported in the form. 

CONFIDENTIALITY CLAIMS 

You may claim any information in this notice as confidential To assert a claim on the 

form, mark (X) the confidential box next to the information that you claim as 

confidential, To assert a claim in an attachment, cin:le or bracket the information you 

claim as confidential. I{You clajm information in !he notices as confidential you must 

also DTOvide a sanitized version of!he notict. (jncludjng attac!unenW. For additional 

instructions on claiming information as confidential, read the Instructions Manual. 

D Marie. (x) if any information in this notice is claimed as confidential. 

TEST DATA AND OTHER DATA 

You are required to submit all test data in your possession or control and to provide 

a description ofall other data known to or reasonably ascertainable by you, if these 

data are related to the health and environmental effects on the manufacture, 

processing, distribution in commerce, use, or disposal ofthe new chemical 

substance. Standard literature citations may be submitted for data in the open 

scientific literatunt Comolete test data <written in English), not summanes of data. 

must be submitted ifthev do not aDoear in the ODen literature. You should clearly 

identitY whether test data is on the substance or on an analog, Also, the chemical 

composition ofthe tested rrwerial should be characterized Following are 

examples oftest data and other data. Data should be submitted according to the 

requirements of §720.50 of the Premanufacture Notification Rule (40 CFR Part 

720), 

Test Data (Check Below any included in this notice) 

Environmelltal fate data lfJ Yes Other data 0 Yes 

Health effects data 0 Yes Risk assessments 

Environmental effects data 0 Yes Structure/activity relationshlps 

Physical/Chemical Properties· KI Yes Test data not in the posseSSlon 

or control of the submitter 

• A physical and chemical properties worksheet is located on the last page of this form. 

TYPE OF NOTICE (Check Only One) ~ 

~ IX] PMN (Premanufacture Notice) 	 .::l: 

;1:'.. 0:::0 

-< ."'];1 D lNTERMEDIATE PMN (submitted in sequence witkSnaI p""e}'~) 

o -In, D SNUN (Significant New Use Notice) 


D TMEA (Test Marketing Exemption Application) s> 


D LVE (Low Volume Exemption) @ 40 CFR 123.5~1) 

D LOREX (Low ReleaselLow Exposure Exemption) @40Cm 723.50(cX2) 


LVE Modification LOREX Modification 

IS THIS A CONSOLIDATED PMN? Yes 

D 	 D 

D 

# ofchemicals 


(Prenotice Communication 1# required, enter 1# on page 3) 


EPA FORM 7710·25 (Rev. 5·95) Replaces previous editions of EPA Form 77\0·25. 

PUBLIC COpy 
Public reportmg burden tor thiS collection ot Intonnatlon IS estimated to average 110 nours per response, Includmg ttme tor reviewing 

instructions, searching existing data sources, gathering and maintaining the data needed, and completing and reviewing the collection of 

infonnation. Send comments regarding the burden estimate or any other aspect ofthis collection of information, including suggestions for 

reducing this burden. to Chie( Information Policy Branch. PM-223, U.S. Environmental Protection Agency, 401 M. St, S. W., Washington, D.C. 

20460; and to the Office ofManagement and Budget, Paperwork Reduction Act (2070-0012). Washington, D.C. 20'03. 

CERTIFICATION 

I certify that to the best of my knowledge and belief: 

1. The company named in Part I, section A, subsection la ofthis notice form intends to manufacture or import for a 

commercial purpose, other than in small quantities solely for research and development, the substance identified in Part I, 

Section B. 

2. All information provided in this notice is complete and truthful as of the date of submission. 

3. I am submitting with this notice all test data in my possession or control and a description of all other data known to or 

reasonably ascertainable by me as required by §720.50 of the Premanufacture Notification Rule. 

Additional Certification Statements: 

If you are submitting a PMN, Intermediate PMN, Consolidated PMN, or SNUN, check the following user fee certification 

statement that applies: 

[gI The Company named in Part I, Section A has remitted the fee of $2500 specified in 40 CFR 700.45(b), or 

o The Company named in Part I, Section A has remitted the fee of$1 000 for an Intermediate PMN (defined @ 40 CFR 

700.43) in accordance with 40 CFR 700.45(b), or 

o The Company named in Part I Section A is a small business concern under 40 CFR 700.43 and bas remitted a fee of $1 00 

in accordance with 40 CFR 700.45(b). 

If you are submittin~ a low volume exemption (LVE) application in accordance with 40 CFR 723.50(c)(l) or a Low release 

and low exposure exemption (LoRex) application in accordance with 40 CFR 723.50(c)(2), check the following certification 

statements: 

o The manufacturer submitting this notice intends to manufacture or import the new chemical substance for commercial 

purposes, other than in small quantities solely for research and development, under the terms of 40 CFR 723.50. 

o The manufacturer is familiar with the terms of this section and will comply with those terms; and 

o The new chemical substance for which the notice is submitted meets all applicable exemption conditions. 

o If this application is for an LVE in accordance with 40 CFR 723.50(c)(I), the manufacturer intends to commence 

Confidential 

manufacture ofthe exempted substance for commercial purposes within I year of the date ofthe expiration of the 30 day 

review period. 

EPA FORM 7710-25 (Rev. 5-95) Page 2 

la Person 

Submittinl 

Notice (in U.S.) -icD;;;.;;J~a~m~e:....::s~M~u~m:.::b:...t.._______...L-_D_~_·r_e_c_t_o_r_,=--_E_H_&_S________ 

b. Agent (if 

applicable) 

VANTICO CORP. 

281 Fields Lane 

Brewster, NY 10509 

Telephone 

c. If you are submit1tiilgtithiiiisiinouiOili'ce;;aasSipartPliioof:fal]joi01iiiinttisaiiubbrmiiiissss:iiiion~,~miUarkiiki(X)XfthiiiiiS'sbOiC:-:~====~=====::::=====.Lr 

Joint Submitter (if 

applicable) 

Contact (in 

U.S.) 

Company 

Dr. Jame 

VANTICO CORP. 

and street) 

281 Fields Lane 

Code 

Brewster, NY 10509 

Director, E H & S 

Telephone 

914 785-3382 

3. 

4. 

substance ~vered by tllillIOtice. ...the CXIIIIIpIioa 1IUIIIber lllipeel by 

EPA. If you previously submitted. PMN forlllil subaace __tile 

PMN number lllipod by EPA (i.e. witbdrawn or ilIcompl.). .. 

5. 

for the chemical sub__ ~vered by tIIiI notice, ...tile nacice number 

assigned by EPA. .. 

I. Manufilcture 

6. Type ofNotice • Mark (X) Only

D SindinlOption 

Mark 

52-000000135 


2. Import 

Only

D Sindinl Option 


Mark 


Mark (X) to [!l if none 

Mark (X) to [Xl if none 

Mark 

ifnone 

(X) ... D

3. D Both 

EPA FORM 7710·25 (Rev. 5·95) Page 3 
X 

Part I - GENERAL INFORMATION - Continued 

Section B - CHEMICAL IDENTITY INFORMATION: Yw .... aCWl'lllU, c:rlmKtQcUcal AbllI'Ida (CA) - 01 WIIoI__ bUIlt 011 W Nl'ltII CaIl«llwlM. (9C) 01 CA ruleI and COIIIWlltiGN. 

Campllta lith... i ..... 1 IC'Lue 1 or 2 ...bfiUce.) or 2 lPolymln» .. appropriate. Compl ... aU other ita... 

I.f another penon will submit chemical identity inlonnatioa for you (lor either illlan 1or 2), mek ()O the box It the rtpt. 0 

the ill a continuation sheet. ....

1. ClaM 1 or 2 c:hemicallUbltUlc" (lor de:finiliona 01 cla. 1 and a- 2 subltan~ _ the but:nactioa. Manuij 

•. au. 01 substance - Mark 00 1 [gJ a.. 1 01' 2 D a.. 2 

b. 	Otemical name (Currently correct OIemical AbII:ncts (00 Name that II canslltent with TSC.A lnveneory Iist1np for Ii.mil.ar subltanca 

For C ... 1 subltanca I CA lnc:lu NI.IM mUll be provict.d. Far a.a. 2 ,~ethe I CA lnc:lu NI.IM or CA Prtt.,-ed Name 

be provided;. whichev.. 11 appropriate bued 01\ CA 9CI noDMndalW'e I\Il.a and conventllDnL). 

c. Please identify which method you usecllo dlMtlop or obtain the IpId.Iled chtmicall.ndcltlty inlcrmatlcn NpCII'ted III t.hiI ftOt:\c:c 

(check one).D Method 1 (CAS Inventory Expert s.mc.. a copy 01 the Ideli&:atloD OMethod 2 (Oth..Soun::.) 

report obtained from the CAS Inveneory Expert Service mUll be 

submitted ..an attactuMnt to t.hiI notice) 

• 

X 

e. 	For a cia .. 1 subltana. provide a QOD\pIna and ccnect c::l'Iemkalltl'\lCtUft dLagrlDL Far I ca..1IUbItancI- (1) UIt the lmmedllta 

precunor IUbltaJ.'Ica With their repedlve CAS Reptry Num'-r. 0.) o.crtbI the natun 01 tbI....::tiaD or (3) Indicata the X 

range 01 COII'IpoIitioa and the typical cccnpolitloD (wh..IppoprIale). (4) Provide I a:ma:t ..t1ve or partial chemical 

,t:tuctI.\re djaWam, .. cccnpleta .. c:III\ be known. II oM ca be r.toaably ~ 

X 

FURM EPA 71lG-25 CRw.5-95) 	 Pap" 
Part I - GENERAL INFORMA nON ­ Continued 

~ Section B - CHEMICAL ID'ENTlTY INFORMAnON - Continued 

z. PoIymas (For a de6nitiOft of poI)'1Mf, ,.the IDRnlctlOil. MauL) Not Applicable (N/A) Caafl. 

4mdal 

a. Indicate the numba'-averap wept of the Iowwt &nOlecular -&hi campalitiaD 01 the poI)'1Mf you Inlef 110 m.eulactur& 

Indicate muim1Ull wept ~t01 low molecular wept tpec:W (not lDdudJrlll"llidulllllClllCllllln. t.....or dv....) bIIow 

500 and below I,CXXI abIolute mollcu.lar weisht 01 that campaliticn. 

Duc:ribe the methoa oi m........ent or the INa. far yau.r .ltiInatec GPC 0 OtNrD ! (SpIdfy) 

I) 10'" ftUlZlbc IYII'IIp w4li8ht: 

U) m&1dIm.Im w.qht below 5ClO moIIIcWaI' WIIIpt: 

Iii) II\IlCia\UIZI ~t below 1000 moIIIcWaI''MIIflIl:

o Mark CO this box j.f you attach a COl'Itb'luation ..... 

b, Yau mUlt make !lllpU'ate CXlft8denttalJ.ty c::I.aUN far II'IIClIlClIMI' or other ractut I.dmtlty, campolitkla INonnaIioa. and reriduallniormatlcn. 

Mark 00 the "Confldaltial- box nat to any I..you c::I.II.III • ClIlftftdmtlal. 

(1) - Provide the sped.8c c.hcalaIl nama and CAS R.eptry Numba' (If a num_ aiIta) 01-= IftCIlOI:Mr oroth" ractant UIId.ln the N / A IJW\Wactureof the polymer. . (2) - Mark 00 this column j.f _ay in colWM (1) II con8_1W. 

(3) - Indicate the typical wept per<alt 0I1iId\ meaomer or other r.:tant lD ther.l)'1Mf. 

(4) - Mark UO the td.ntity' cahuDa II 1011 waat a _om.. or ........C'IIIiit 11M ..two w.tpt paaat or lIM to be lUted ..put of the 

polymer dftCriptiaa 011 the TSCA. QIIIIIkal SabItaDce laY......,.. . (5) - Mark 00 this coIUD.'ID j.f _tn.·1n columnt (3) and (4) InClIlftftdmtlal. 

(6) - Indica.. the muim1Ull wtipt .-c-t01-= mea...or oth8' reKtant that may be ~t.a rlillldWIIlD 1M pol)'1Mf. 

m- manufactured Mark 00 this column 

far CIXl'IIDtI'dal 

j.f _ay III 

~ 

colUDUl (6) lit c:on8_1W. 

Moncm..or other r.ctant and CAS R.eptry Num_ Coa.ft,. ~. Identity o.a. Maximum 

(1) d..

(2) 

tiaI 

Gi Mark 

(4) 

00 deadal 

(51 

AlidWII 

(6) 1=('7) 

N/A " " 

" ." 

" " 

" " 

" '5 

" '"' ,

, 

o " " Mark (X) this box if you attach. cantb'luatIcD .... 

e. PI...identify wb1ch mlllbod you 1II1II to dewlap or oMIDl theIpIdIled c:MtrdaIl.dmtity tnIarmadi:Ia.....in thia DOt.IcL (cbec:k cae). o Method 1 (CAS IDventary

=s.mc.-a CICIpf oi the kilatllcltlaa rapan 0 Metbod 2 ( ....1DUIa) 

obtaiDed fram In'Mltory rxp.ts.w..".be IIIbmitIIId • . an attac.hmmt to tJU. ~ 

d. The currmdy CXlIl'C Qemical AbItndI (CA) ftIIIDI far the pal".. that lit wtIb 1'SCA laftlltory IIItInp far IUN1ar pal,..... 

W/A 

e. Provide a correct iept_bld..or patW ch.aIal tII"IIII:tUre.........campWI. <*l btmow..tlOM <*l bt ~1-.t1ined. 

N/A '. -

o MarkOO tIUbox II you attacb a caatilluatlaa ..... 

P1Ip5 .s. ­

'. 
(a)· 	 Identify e8I:b impurity that may be reasonably anticipated to be present in the chemical substance u manufactured for commercial purpose. Provide the 

CAS Registry Number ifavailable. Ifthen! are unidentified impurities, enter "unidentified. " 

Number Confidential 

% X 

% X 

% X 

% 

% 

% 

% 

Marlt (X) this box ifyou attach a continuation sheet. 

in subsection 1or 

RD 2000-040 

o " Marlt (X) this box ifyou attach • continuation sheet. 

6. Generic you must a generic name for your 

the specific chemical identity ofthe new chemical substance to the max.imum extent possible. Refer to the 

TSCA Chemical Substance Inventory, 198.5 Edition, Appendix B for guidance on developing generic names. 

polyphenol, 2H-l,3-benzoxazine derivative 

use, or 

None 

X 

the CAS Registry 

EPA FORM 7710-2.5 (Rev. 5-95) 	 Page 6 
Part 1- GENERAL INFORMATION - Continued 

Section C ­ PRODUCTION, IMPORT, AND USE INFORMATION: 

Mark (X) the "ConfidentiaP' box next to any item you claim as confidential. 

1. ProductioD volume - Estimate the maximum production volume during the fltSt 12 months of production. Also estimate the maximum 

production volume for any consecutive 12-month period during the first three years ofproduction. Estimates should be on 100010 new chemical 

substance basis. For a Low Volume Exemption application, if you choose to have your notice reviewed at a lower production volume than 

10,000 kg/yr, S'DCCify the volume and mark (x) in the binding box. Ifgranted, you are bound to this volume 

Maximum first 12-montb production (kglyr) Maximum 12-month production (kglyr) Confi- Binding 

( 1 00% new chemical substance basis) (100% new chemical substance basis) dential Option 

Mark: (x) 

kg/yr kg/yr X 

1. Use InformatioD - You must make separate confidentiality claims for the description of the category ofuse, the percent of production volume 

devoted to each category, the formulation of the new substance, and other use information. Mark (X) the "Confidential" Box next to any item 

you claim as confidential. 

a. (I) ­ Describe each intended category ofuse of the new chemical substance by function and application.. 

(2) -­ Mark (X) this column if entry column (I) is confidential business information (CBI). 

(3) _. Indicate your willingness to have the information provided in column (I) binding. 

(4) ­ Estimate the percent of total production for the first three years devoted to each category ofuse. 

(5)­ Mark (X) this column if entry in column (4) is confidential business information (CBl). 

(6) ­ Estimate the percent of the new substance as formulated in mixtures, suspensions, emulsions, solutions, or gels as manufactured for 

commercial purposes at sites under your control associated with each category of use. 

(7) ­ Mark (X) this column if entry in column (6) is confidential business information (CBI). 

(8)­ Indicate % of product volume expected for the listed "use" sectors. Mark more than one box if appropriate. Mark (X) to indicate 

your willingness to have the use type provided in (8) binding. 

(9)­ Mark (X) this column ifentr r'(ies) in column (8) is tare) confidential business information (CBl). 

Category of use (1) CBI BlndiIII Produc· CBI %in CBI % of substance expected per use CBI o,tiooo tion% Fonn­ (S) 

(by function amd application i.e.• dispersive dye M.t(x) ulation Site- Con-· Indus· Com- Binding • for fmishing polyester fibers) (2) (3) (4) (5) (6) (7) limited sumcr trial mercial Option (9) 

Resin for electronic X X X laminates % 0;' 

Adhesives Resin X X X 0;. % 

Encapsulants Resin X 

% e;.. X X

I X X X I Composi tes ResiQ, 0;. 0;. 

i 

• 

% % 

0;. 0;. 

% % 

• [(you have identified. "consumer" use, please provide on. continuation sheet a detailed description ofthe use(s) of this dtemical substance in consumer products. 

In addition include estimates of Ibe concentration orthe new chemical substance as expected in consumer prodUds and describe the chemical reactions by which this 

substance loses its identity in Ibe consumer product. 

DMark: (X) Ibis box if you attadIa continuation sheet. 

b. Generic If you claim aD)' category of usc description in subsection 2. as confidential. enter a generic description of that category. Read the 

use instructions MmuaI for examples of generic use descriptions. 

description 

N/A 

D Mark: (X) this box ifyou attach • continuation sheet. 

3. Hazard IoformalioR ­ Include in the notice a copy of reasonable facsimile ofany hazard warning statement, label, material safety data sheet, or other ! 8lnding 

infonnation whidl will be provided to any person who is reasonably likely to be exposed to Ibis substance regarding protective equipment or practices Opuon 

for the safe handing, transport, use, or disposal ofIbe new substance. List in part OJ hazard information you include. Mark (x) 

[!] Marie. (X) Ibis box ifyou attadI hazanl infonnation. MSDS - Pages 14 - 17 

EPA FORM 771(l.25 (Rev. 5·95) Page 7 
Part II ­ HUMAN EXPOSURE AND ENVIRONMENTAL RELEASE 

.. of the lite ItwIUdl the 


Name 


Not Applicable - Import only 


SUe 

Uthe same opcradoa will oc:cur at more t.h.ul OM Ii... 1ft. tht nWllw 01 Ii_I_lily tht 


add1ticNllit. on • contlnuadoa aheIt. and 111ft, 01 til. lit. have IIp!cantly dUHret .... ' 


pt'O<luctSon ru. CI' operatioN, induct. aU the Il\.&JnrIadoa III tl'IiI-=tiCIft fer tbcIe 


b. 	Typa­ N/A


Mark 00 o Prooo.ml DUM 


1. Bate 

do Prac.. daalptlaft Mark 00 _ ladlallt,....wUUap__lIaYe J'OIII' procaI .. 

(l) 	DIapun the ma;ar unit op.-attoa 'IIIpIU'Id cMIIiaIl CDftYel'!ll.all& IDdudeiDIIItm....IftClIr.........' CItII\tai.ntn (1IIJI'I'CIIy-e." 5pI.\cxI pai.lI. 55 

p.IJon drum. rail ca', tank Ir'UIck. etc.). 

(2) Pnmde the idlmlity. the approx:ImatII M!ipt ('by kllday CI' ksJ'Deldl oa • 1~ MW cMnic:Il.w..nc. "-11), aMlfttry poiDt 01 aU ..tin, ma.....Gad feedIIeocb r.::IIIIlfll,..".... mel Itc.), mclof..produdI...,.......aM "MMa IIIch.ad11 cIIerIin, 

dManicaIa (no-fNquecy II not 1.-.1 dilly 01 PI" 'betdL). 

(3) Ideuily by rnunlMr the pom. of .......iftc:ludInI..al CI' In.-.Nttant NiIIIIII, to .... ~tof the MW c:MadCII.lIUbItanca. 


N/A 

·Confid_lill" box next to any iblm you • 
Part II- HUMAN EXPOSURE AND ENVIRONMENTAL RELEASE - Continued 

Section A ­ lNDUSTRIAL SITES CONTROLLED BY THE SUBMITTER - Continued 

2. Occupational Exposure - You must malee separate confidentiality claims for the description of worker activity, physical form of the new chemical substance, 

number of works exposed, and duration of activity. Marie (X) the "Confidential" box next to any item you claim as confidential. 

(I) ­ Describe the activities (i.e. bag dumping, tote tilling, unloading drums, sampling, cleaning, etc.) in which workers may be exposed to the substance. 

(2) - Marie (X) this column ifentry in column (1) is confidential business information (Cal). N tAl' b 1 

(3) - Describe any protective equipment and engineering controls used to protect workers. 0 p p cae 

(4) and (6) - Indicate)'Our willingness to have the information provided in column (3) or (5) binding. 

(5) -Indicate the physical formes) ofthe new chemical substance (e.g., solid: crystal, granule, powder, or dust) and % new chemical substance (if part ofa mixture) 

at the time of exposure. 

(7) - Mark (X) this column if entry in column (5) is confidential business information (Cal). 

(8) - Estimate the maximum number of workers involved in each activity for all sites combined. 

(9) - Mark (X) this column if entry in column (8) is confidential business information (cal). 

(10) and (11) - Estimate the maximum duration of the activity for any worker in hours per day and days per year. 

(l2) - Mark (X) this column ifentries in columnsilO) andtIl) are confidential business information (cal). 

Worker acuvity CBI Protective Equipment! Bindinl Pbysical forms(s) Bindin. CBI II of CSI Mmumu dlll'lllion CBI m 

(i.e., bag dumping, filling drums) Engineering Controls 0pIi000 and%_ Opboft Worker HrsIday Oayslyr MItt (x) subltance MItt (x) s 

(I) (2) (3) (4) (5) (6) (1) Expose (9) (10) (II) (12) 

d 

(8) 

N/A 

[ J Mark (X) this box ifyou attach a continuation sheet.. 

3. Environmental Reteue aad Dbpoul- You must make separate confidentiality claims for the release number and the amount ofthe new chemical substance 

released and other release and disposal information. Mart (X) the "Confidential" box next to each item you claim as confidential. 

(I) ­ Enter the number ofeach release point identified in the process description, part II, section A. subsection Id(3). 

(2) - Estimate the amount ofthe new substance released (a) directly to the environment or (b) into control technology (in kg/day or kglbatch). 

(3) - Mark (X) this column ifentries in columns (I) and (2) are confidential business information (cal). 

(4) - Identity the media (stack air. fugitive air (optional__ Instruction Manual), surface water, on-site or otf-site land or incineration, POTW, or other (specify)) to 

which the new substance will be released ftom thai release point 

(5) ­ a. Describe control technology, ifany, and control efficiency thai will be used to limit the release of the new substance to the environment For releases 

disposed ofon land, characteri7.e the disposal method and state whether it is approved for disposal ofRCRA hazardous waste. On a continuation sheet. for 

each site describe any additional disposal methods thai will be used and whether the waste is subject to secondary or tertiary on-site treatment b. Estimate 

the amount released,to the environment after control technology (in kw'day). 

(6) - Mark (X) this column ifentries in columns (4) and (5) lire confidential business information (Cal). 

(7) - Identity the dcstination(s) of releases to water. Please supply NPDES (National Pollutant Discharge Elimination System) numbers for direct discharges or 

NPDES numbers ofthe POTW (Publici Owned Treatment Works). Mart (X) if the POTW name or NPDES II is confidential business information (C81). 

Release AJnountofnewsubstance Cal Mediao( Control technology and effiCiency (you may wish to optionally attach effiCiency data) cal 

Number released rel_ 

(I) (2a) (2b) .... -. Blndin& I 

(3) (4) (Sa) • MItt (X) (5b) (6) I 

I 

N/A 

I 

I 

~ 

(7) Mark (X) th~ D POTW provide name(s) below: eBI D Navipble D Other· Specity provide NPDES # CBI 

destination(s) of r-­ waterway 

releases to water. fiLA 

] Mark (X) this box ifyou attach a continuation sheet.. 

EPA FORM 7710-25 (Rev. 5·95) Page 9 
Part II - HUMAN EXPOSURE AND ENVIRONMENTAL RELEASE ­ Continued 

Section B - INDUSTRIAL SITES CONTROLLED BY 0'nIERS 

Comp/llte Mdion Bfor ~_pnlICIIIUl,..or '13M opatianl iIlvolvillS the new It..you do.l'IOt control.~· for typkai 

Manual 

mmufac:turilll 

Complete 

or pr~1

a..,...... 

opentkml 

Mdlon B_-:;mol tile DIIW chImk:alort.e:1tGa 

....c.1t SIll 

iIlYol~

ouIIIde the 

tile newdMadcal........ 

u.s. that you do not ccalnlHle 

II the ......

~ 

opattoa it 

pertarm.lat more tlwt one ...deIcrUIe tile ~1tGa CDINDOll to ...... leila addlttoaalll_ on a ClXltIm.IItkm aMat. optioDa1 fer 

,Ues out31de the United Stata·See •. :H. 

1. Operation OellC1i.ptiOll • To daUn Information ill dU MCiion • CCII1IidenIUlL cLrcIe or brac:Ut tile tpId6c that you cWm • CIIlIII.8detial. 

(1) - Diasnm the major u:nlt ope'Ition aDd chemk:Il ClXlYIrIIIIona, Indudlnf iIltnn.....and II'anrIpCIt ClXltIU:Ias (8plCify-5 plIeD palla, 55 

gallon drumIt, rail an, tank !.nidal. etc). the ldetily byI.­_ brWIr, dIIcribe -=h wonc. ICtMty. (2) ­ the idettty, 

the approxima. weght (by kllday or k,/blaldl, 1 MW dMmiaIllU.bItarIct btIU , and Ifttry potat 01 aU I-.:IIIodc. (IIldudln, r.ctantl, 

solveI'll. and catalysts, etc) and 01 all produc:tI. r~ItnIaDW, and WlIIta &Ic:lude c:IeIuI.ins c:MmJcaII (not. II Aot WIed cbIly or per 

batch). (3) ­ [dent:iIy by numb« the pointl 01 reltut, iIld1.ldi.nS IIIWl or iZltennittIrIt r.-... to tile _vlroinmIftt 01 the MW c:hImica1lUb1tanca. 

Entll' , of .it.. [ CONFIDENTIAL . 

35% to 80% PMN resin 

+ 

20% to 65% solvent + other resin 

t 

Copper-clad laminate or printed wiring board >­ curing operation 

W G) 'G) t 

o Mark 00 th.itt box II you attad:la ClXltImIadan .... Finished article 

2. Worka' Expo.anfIIl'riroe1ll!lelltal a ...... 

(2) 

(1) ­

- Ettimate 

From tbedlapm 

the l\\lIIIbcoi 

ebow" ~""forprovide the we.far-=h 

aD ...era..... 

1di:I.YUJ. Cia,.. 2-1 far .. Idi:I.YUJ ~ 

(4) - Ettimate the typtal duration oI41XJ'011'ft PIIIr W'CIIkIW III (a) houn per .,_(b) .,..per y... 

(6) ­ Oeacrt'be phyaca form of.....and. .. DeW ct.atal auJwtencp Of fa 1IlildLft), II!d.,proIIII:Iiw tquipIDIftt and ~.cantrolt, ilmy 

UMc:i to~ 'MIl.... 

m- Estimate the pIICIIIIlt 01 the MW .w.__ • fomwIatlld ,...J*bp:Ior....a rlDal procl1Kt. 

(9) ­ From the c:IiAIsnm abcml, __ the IIUIIIM 01..r--.paIDt. Cia,.. 9-U tor..r.a- paiN kMDtIW. 

(10) ­ Estimate the lD\ount 01 the MW.........a....d(a) diI'IcIl, tothe~ or (\I) IDtocadrOl tIId\ftoiog 110 the .Vir'onIDent 

(Ill tllday or kll.tdU. • (12) ­ Oeacrt'be media 01 .......(tIIICSair, 1uiI*M""(=~M.uaD, ___wu., 0IHtta or .....1and or IRc::b:IcItiCIl, POtW, ar other <sp.:ity» and. ccatral IDY, wm1lll...110 limit the __01 the MW IUhItaDot 110 the.¥ill:mmlat. 

(14) - [dtntily byproductl wbtch ...y NaII.t the aperatka. . 

(3), (5), (8l1 (ln, (13) and. (15) • tart 00 t:bII coIuma If -lIlY' 01 the 1IddM..Cl:lllildmtlal bulineallafcnnaItGa (CII>. 

Lett. '01 CBr Dundal C8I J'rOClKllw Squ1p. I I:c:.. CBI .... AmauIltol CBI Contral 01 

of Worbn 01 ",..,......CAAtt:oIIII NumIMr New TIChncIosY 

ivity 

Act· ExpoMd ExpoIuN 

DeW 

PhJlllCll ......... FanDII!d .. WaIlea 

rw...l 

~ 

I 

('1) <lOU : <lOb) <11 (12) (1) (2) (3) C4a) I ("It) (5) (6) (8) (9) (13) 

A 2 8 I 30 gloves. goggles X 1 0 :< lkE Lined landfill I apron,exhaust I 1/ day I L 

I Slo.ves • gogg les X WA N/A B 2 8 130 I'N/ A N/A

apron, exhaust I -

I 1 I 

I I 

I I 

I I 

I I 

I I 

I • I 

(14) -1JyprocIuda (5) 

None 

TI M..x 00 box ifyou.tIIICh.~ .... 
Part 11-·HUMAN EXPOSURE AND ENVIRONMENTAL RELEASE - Continued 

~ Section B - INDUSTRIAL SITES CONTROLLED BY O1HEKS 

CompieM MCtica Bfor typicU procIIIIIinlor \Ale opnticN involvi.nl the IIoIW tuietanCIIIt ..you do not (X)ntrol. ~NLl for typical 

manufacturinlor 

MuUII. CoatpIMe 

pt'OCIIIiDl 

• ..,.,...

opIrItXmIlIlYDlvtns 

MCI:lca Bfer -:.:mthe cI. 

DIW 

procIIII.nt. 

chIaUcI.lll.lllet.alCIIIt 

or \.e =tSemlll~

..ouaide the 

1M MW 

u.s. that 

cI'IIIIIical 

you do 

tubManc:& 

not QlIltroH. 

Uthe tmle 

~ 

opIl'ItIaI it 

perfCllmec1.t more thaD OM ..dllc:ribe the r;;.~.d.oa CDINl'IClI'IIIO ..... I addiltoNl !III.. em • canlbludGa sMIt. optkeal far 

sites outside the United. Stata·SIll rn. M 

1. Opuatiaa OetcriptiOll • To daim Informaticn in thia MCtion • c:&mfide1ilL circM or bracbt thelJ*ific inlonnad.cIIliIat you claim. c:on8detW. 

(1) - Olagram the major u:ni.t operatioa aDd cMmk:al canVftcl:'ll" 1Ddud1ns inteUn .....Iftd InNIport cantlUMn (tpedfy-5 pike pIibI. 55 

gallon c:Iruma, rail cars, IarI.k trucb,...,. the dial::; IdtIItlfy by len. and brWly dIIc:rtbe -=II wwlr«lId:lvUy. (2) ­ Provide the IcLmttl:y, 

the approJdm... weight (by kglday or kg/bltcb. 1 new chlDdallUblluCll ....), and ...., poUlt oll1lt.Ultock. (lndudbag r-=tanlll, 

501valtl and catalysm.etc:) and 01 all products. fecydl Iftd w--.lnc:ludl deaninl cbeINcaII (note &.quincy if not used daily or i* 

batch). (3) - ldentily by numba' the pointa of nl-.indudinllll'lall or in~re-. to the tIlvinllurlent 01 the IIoIW ch.mkalIUbttanCil. 

Enter. of .it.. [ ] ~ONFIOENTIAL 

PMN resin 

(9 

t

heat 

Hot melt application to adhesive or encapulant substrate 

t W 

® Curing operation 

n Mark 00 thia box if you .ttadl. CCIIlIimIIdIcn IMIt. 

1. Wariur ~viI'aeIDe.III1 ••"'" 

(1) 

(2) -

­

EstimIlil 

Prom the 

the 

cU.qruD 

nUlllM 

abow, 

cI. W'GI':bn

prvv1I:W ....the IItIiIr

for 

lar.c:b,...... 

aD Ill.. ~ 

&:ttvtly. 0..... 2-Ilar.c:b III:tlvUy ~ 

(4) - Ettimalll the typical duratla.'l cI. .....pIr wwka'ill (a) houm fill' .yIftd (b) day.fill' .,... (6) - DlBatbe phylllcll farm cI. ecpcIIUN aDd" newcbIadal.JbItaDct (If tDlldxtuN), 1IId., pnAIIidiIw equtpmet and ~gCIXIlrOliI. itmy 

UMd to prollect wor.... m- EttimaliI the ~t01 the new .abMmce _ lamulalild .....pKkIpI CII' ___• &IIIl procluI:L 

(9) ­ From the~~.bow. til"the ~01"" Nll-.pr:.iUd. c.p-t-Utar ....NIl-. poiIIt lderitls.l 

(10) ­ &timalll the all'IOUftt 01 the new..............(a) dlnedy 110 the or (b) IDto caatn::Il ta:hnoIo&Y 110 thI ..vironmIDt 

(Ill kg!day or kg/bMcb). • 

(12) - DlBatbe medii 01 __<ltldialr. fu&iaM" (opdOinI.HII ~MeuID,....wae., 0IMiIII or off.....land or 1adDendca, POTW, ar oth. esp.:ify» aDd CCIIltrell tIch~.." ..... wiD 1111 __ 110 limit the __01 the I\IIWIU11ItaftCIIIIO the.'YIroIImct. 

(14) - identify byprcduct:l wht.cb may r..at the opnIk& 

(3), (5), (8), (11), (13) and (15) • Ma-k 00 tIdII caIuIaa tf .ycI. the tIltIW..ClClDftdetl.ll buIiDIM inlwmatkm (CII)-. 

Letter '01 CBI 0uratIma CB Proea:dV'e !quip. I I". em a.... AmouDto( CBI Cantrell CBI 

01 Worbn 01 ....,;ldalCaiDeralltI ~ NIW' TedInolosY 

ivtty 

Act· ExpaNd ExpoMn ....,

JIb,.. .......... ParDlIlld " .... ...... 

~ 

I 

m ClOl) : Clot. Cll (1) CZ) (3) (oW I (4b) (5) (6) (I) (9) (12) (13) 

I ~loves, goggle!: I 

I I( lkgl Landfill or 

A 2 8 ! 30 ~pron, exhaust X 1 0 Iday incinerator 

B 2 8 : 30 ~loves, goggles X N/A N/A:NIA N/A 

I !apron, exhaust I 

I I

: I 

I n I I 

I I 

I • I 

(14)-~ (15) 

None 

I 0 M.x 00 tJU boll: if yvu .ttadl. CCIIltlm__.... 

FORM EPA 1'1lCJ.2S (1ft. 5-95) PaplO a 
Part II-- HUMAN EXPOSURE AND ENVIRONMENTAL RELEASE ­ Continued 

Section B - INDUSTRIAL SITES CONTROLLED BY OTHERS 

Complete se<:tion B for typical processing or use operations involving the new chemical substance Olt sites you do not control Importen do not have to complete this 

section for operations outside tho U.S.; however, you must report any processin& or use activities after import. See the Instructions Manual Complete a separale 

section B for each type ofprocesnng. or lise o~ration involving Ihe new chemicailllbstance. Ifthe same operation is performed at more than one site describe the 

typical operation common to these sites. Identify additional sites on a continuation sheet 

1. Operation Description - To claim information in this section as confidential, circle or bracket the specific information that you claim as confidential. 

(1) •• Diagram the major unit operation steps and chemical conversions. including interim storage and transport containers (spe<:ifY. e.g. S gallon pails. S S gallon 

drums, rail cars, tank trueb, etc). On the diagram. identifY by letter and briefly describe each worker activity. (2) - Provide the identity, the approximate weight 

(by kw'day or kglbatch. on an 100% new chemical substance basis). and entry point of all feedstocks (including reactants, solventl and catalysts. etc) and all 

products, =ycle streams. and wastes. Include cleaning chemicals (note frequency if not used daily or per batch). (3) - IdentifY by number the points of" release, 

including small or intermittent releases, to the environment ofthe new chemical substance. (4) Please enter tho /I ofsites (remember to identify the locations of 

these sites on a continuation sheet): 

CONFIDENTIAL~ [ 1 

/I ofsites 

35% - Formulation containing the PMN chemical 

+ 

65% - Carbon or glass fiber 

Prepreg ~ operation :> Molding and curing operation 

ill @ ® t 

Finished article 

o MIIlk (X) this box ifyou attach a continuation sheet. 

2. Worker ExposurelEnvironmentai Re1_ 

(1) - From Ibe diagram above, provide the letter for each worker activity. Complete 2·8 for each worbr activity described. 

(2) - Estimate tho number ofworkers exp080d for all sites combined. 

(4) - Estimale the typical duration of exposure per worlc.er in (a) hours per day and (b) days per year. 

(6) - Describe physical form ofexposure and ." new chemical substance (ifin mixture), and any protective equipment and engineering controls, if any, used to 

protect worIc.er.: 

(7) - Estimate the percent ofthe new substance u formulated when packaged or \lied u a fmal product. 

(9) ­ From the process diagram above, enter tho number of eaclI release point Complete 9-13 for ead! release poiJIl identified. 

(10) - Estimate the amount ofthe new substance released (a) directly to the enviroruneDl or (b) into control technology to the environment (in kw'day or kglbatch). 

(12) - DesCrIbe media ofrelease i.e. stadt air, fugitive air (optional·see Instructions Manual), surface water, OIHite or off-site land or incineration, POTW, or other 

(specify) and control technology, ifany, that will be used to limit the reJeuo ofthe new substance to tho environmml. 

(14) - Identify byproducts which may resuh from tbeopenlion. 

(3), (5), (8), 11). (13) and (IS) ­ Mark 00 this column ifany oftho proceeding entries are confidential business~nformation (CBI). 

Letter l#oC CBI Duration CBI Protective Equip. I %in CBI Rel_ Amolllltof CBI Media of Release CBI 

of Worlcers of Engineering ControlS{ Form- Number New & Ccntrol 

Act· Exposed Exposure Physical Form and % u1atioft Substlllco Technology 

ivity new substance Releucd 

(\ ) (2) (3) (4a) (4b) (5) (6) (7) (8) (9) (\Oa) (\Ob) (1\) (12) (13) 

A 2 8 30 gloves, goggles, apron, X 1 0 <lkg Lined 

exhaust !day landfill 

8 2 8 30 gloves, goggles, apron, X N/A N/A N/A 

exhaust 

14) •• Byproducts: (15) 

none 

EPA FORM 7710·25 (Rev. 5·95) Page lOb 
OPTIONAL POLLUTION PREVENTION INFORMATION 


To claim infonnation in this section as confidential circle or bracket the specific infonnation that you claim as confidential. 

In this section you may provide information not reported elsewhere in this form regarding your efforts to reduce 

or minimize potential risks associated with activities surrounding manufacturing, processing, use and disposal 

ofthe P?v1N substance. Please include new information pertinent to pollution prevention, including source 

reduction, recycling activities and safer processes or products available due to the new chemical substance. 

Source reduction includes the reduction in the amount or toxicity of chemical wastes by technological 

modification, process and procedure modification, product reformulation, raw materials substitution, and/or 

inventory control. Recycling refers to the reclamation of useful chemical components from wastes that would 

otherwise be treated or released as air emissions or water discharges, or land disposal. Descriptions of pollution 

prevention, source reduction and recycling should emphasize potential risk reduction subsequent to compliance 

with existing regulatory requirements and can be either quantitative or qualitative. The EPA is interested in the 

information to assess overall net reductions in toxicity or environmental releases and exposures, not the shifting 

of risks to other environmental media or non-environmental areas (e.g., occupational or consumer exposure). In 

addition, information on the relative cost or performance characteristics of the PMN substance to potential 

alternatives may be provided. 

All information provided in this section will be taken into consideration during the review of this 

substance. See Instructions Manual and PoUution Prevention Guidance manual for guidance and 

examples. 

Describe the expected net benefits, such as (1) an overall reduction in risk to human health or the environment; (2) a reduction in the 

volume manufactured; (3) a reduction in the generation of waste materials through recycling, source reduction or other means; (4) a 

reduction in potential toxicity or human exposure and/or environmental release; (5) an increase in product perfonnance, a decrease in 

the cost of production and/or improved operation efficiency of the new chemical substance in comparison to existing chemical 

substances used in similar application; or (6) the extent to which the new chemical substance may be a substitute for an existing 

substance that poses a greater overall risk to human health or the environment. 

Benefits are as follows: 

The PMN material is more resistant to heat and moisure than the current 

epoxy systems being used in the target applications. This yields a . 

longer lifetime in harsh environments, which reduces waste. It prov1des 

less outgassing than current systems, which also reduces waste. 

In addition, the higher glass transition temper~ture allows higher 


solder temperatures with lower amounts of lead 1n the solder used. 


. l J Mark (X) this box if you attach a continuation sheet. 

EPA FORM 7710·25 (Rev. 5-95) Page 11 
Part ill -- LIST OF ATTACHMENTS 

Attach continuation sheets for sections of the fonn and test data and other data (including physical/chemical properties and 

structure/activity infonnation). and optional infonnation after this page. Clearly identify the attachment and the section of the fonn to 

which it relates, ifappropriate. Number consecutively the pages of the attachments. In the column below, enter the inclusive page 

numbers of each attachment 

Mark (X) the "Confidential" box next to any attachment name you claim as confidential. Read the Instructions Manual for guidance on 

how to claim any infonnation in an attachment as confidential. You must include with the sanitized copy of the notice fonn a sanitized 

, version of any attachment in which you claim infonnation as confidential. 

Attachment name Attachment 

pue number(s) 

Material Safety Data Sbeet tMSDS) 14 - 17 

Physical & €hemical, Properties Worksheet 13 

Conti· 

dential 

Infrared specturm of PMN substance 

Differenctial scanning calorimetry 

18 

19 

Thermogravimetric analysis 20 - 21 

Gel permeation chromatographic analysis 

Mass spectrometric analysis 

Partition Coefficient (n-octanol/water) Study 

22 - 25 

26 

28 - 51 

Nuclear Magnetic Resonance Analysis 27 

, , 

[ ] Mark (X) this box ifyou attach a continuation sheet. Enter the attachment name and number. 

EPA FORM 77l{)"2S (Rev. S·9S) Page 12 
! 

PHYSICAL AND CHEMICAL PROPERTIES WORKSHEET 

To assist EPA's review of physical and chemkal properties data, please complete the following worksheet for data you provide and 

include it in the notice. Identify the property measured. the page of the notice on which the property appears, the value of the property. 

the units in which the property is measured (as necessary), and whether or not !he property is claimed as confidential. The physical 

state of the neat substance should be provided. These measured properties should be for the neat (100% pure) chemical substance. 

Properties that arc measured for mixtures or formu1ations should be so noted (% PMN substance in.-J. You arc not required to 

submit this worksheet; hoftVCIr. EPA strongly recommends that you do so, as it will simplify review and ensure that confidential 

information is properly protected. You should submit this worksheet as a supplement to your submission of test data. This worksheet 

is not a substitute for submission oHest data. 

Property Mark Page Value lMeasum!o Confi. 

dentiaJ (Xl if 

(a) provided 

Physical state of neat substance X 

Vapor pressure X 

ra>. Temperature °C 

Density/relative density X 

Solubility 

@ Temperature °C 

Solvent 

Solubility in water Temperature 22 °C X 

Melting temperature X 

Boiling I sublimation temperaturelOl torr pressure 

Spectra (infrared, mass spectrum) X 

Dissociation constant 

Particle size distribution , 

Octanoll water partition coefficient X 

Henry's Law constant 

Volitalization from water 

VoUtalization from soil 

pH@ concentration 

Flammability , 

Explodability 

Adsorption I coefficient 

Other - Specify DSC X 

TGA X 

GPC X 

NMR X 

number 

(b) (c) 

16 (s) X . (l) 

16 low 

16 1. 18 

16 Insoluble 

16 60 - 80 

2l 8 , 

28-5 

19 

20-21 

22-25 

27 

(g) 

Torr 

2icm3 

JtIL 

2IL 

°C 

°C 

Estimate MIlk (X) 

eM orE) (d) 

M 

E 

M 

M 

M 

M 

M 

t1 

M 

M 

M 

ATTACHMENT 


PAGE 13 

Vantlco Inc. 

North America 

Polymer Specialties 

281 Fieidl Line 

Brewatlr. NY 10501 

a.m to 4:30pm PhOne: (114) 7IS-3OOO 

24-Hour H4MIlthlEnvlronrnentlil EnwgMcy Phone: 1~ 

vantico 


Effective Date: MSDS No: 11075 4/3/02 - Material Safety Data Sheet 

1. PRODUCT IDENTIFICATION 

Trade Name: RD 2000-40 

Chemical FamUy: Benzoxazine 

Health 2 

Flammability 1 

Reactivity 0 

Protective Equipment X 

HMISRATING 

2. COMPOSITION IINFORMA TION ON INGREDIENTS 

0 CAS No. CHEMICAL IDENTITY EXPOSURE LIMITS 

S 

H ACGIH OSHA 

A TWA STEL PEL STEL 

Confidential Benzouzine NE NE NE NE 

CARCINOGEN 

STATUS 

MFR. IARC NTP OSHA 

NE NR NR NR 

NE =Not Established NR =Not Reviewed 

3. HAZARDS IDENTIFICATION 

Emergency Overview: Caution! The toxicological properties of this compound have nol been fully investigated. May be toxic if 

swallowed, inhaled. or absorbed through the mn. May cause liver. kidney and nervous system damage. 

Primary Route(s) ofEntry: Dermal, inhalation. 

4. FIRST AID MEASJJRFS 

Ingestion: If swallowed. immediately give at least 3-4 glasses of water, but do not induce vomiting. If vomiting occurs. give fluids 

again. Do not give anything by mouth to an unconscious or convulsing person. Get immediate medical attention. Have physician 

determine whether vomiting or stoO'la(:h evacuation is necessary. 

SIdn: For skin contact. wash affected areas with plenty of water, and soap, if available. for several minutes. Get medical attention if 

irritation occurs. 

Printed: 411512002 Page lof 4 

Iii 

RD1OOO-4O Vantko Inc. 

Effective D.te: 413102 Polymer Specialties 

Inhalation: If inhaled. remove from area to fresh air. Get medical attention if respiratory irritation develops or if breathing 


becomes difficult. 


Eyes: For eye contact. flush eyes with plenty of water for several minutes. Get medical attention if irritation occurs. 


Medkal Condltlons A .....v.1ed by Exposure: Allergy, eczema or skin conditions. 


Additional Information: Wash contaminated clothing prior to reuse. 


5. FIRE FIGHTING MEASURES 


Flasb Point Method Used: Closed Cup (similar product) 


Fire Fl&btlna ExtInauisbiDa Media: Carbon dioxide. foam. dry chemical. water spray. 


Fire Fl&btlna Equipment: Use self-contained breathing apparatus. 


FIre and Explosion Hazards: Decomposition and combustion products may be toxic. 


6. ACCIDENTAL RELEASE MEASURES 

Acddental Release Measures: Sweep or vacuum and place into closable container for disposal. Wear protective equipment 

specified below. 

7. HANPUNG AND STORAGE 

Precautions: Avoid contact with eyes, skin and clothing. Avoid breathing dust and vapors of heated material. Use with adequate 

ventilation. Remove ~ontaminated noft-impervious clothing. wash before reuse. Individuals should wash thoroughly after handling. 

Avoid dusty conditions. Dust suspended in air may be a tire and explosion hazard. For industrial use only. 

Sto....e information: Store in cool, dry are in sealed containers. Keep containers closed to prevent moisture absorption and 

contamination. 

8. EXPOSURE CONTROLS I PERSONAL PROTECTION 


Personal Protedive Equlp_t: Wear coveralls. 


Skin Protection: Wear impervious gloves. 


Respiratory Protection: Use NIOSH approved dust respirator, if needed. Use respiratory equipment approved by NlOSH for 


protection against aniline mists and vapors. if necessary. 


Eye ProtectIon: Wear chemical goggles if eye contact is possible. 


Engineerina Controls: Work in well-ventilated areas. 


9. PHYSICAL AND CHEMICAL PRQPERTIF3 

Printed: 411512002 Page 2 of 4 

IS 
RDlooo-4O V&Dtico InCo 

Effective Date: 4I3IOl Polymer Specialties 

Color: Yellow 

Odor: No Discernable Odor 

Pbyskal State: Solid 

SolubiUty in Water: Insoluble 

Vapor Pressure: Not detennined. but low at ambient tempcratW'es 

Spedfte GraYity: 1.18 

Meldq Point: 60 - 80°C (140 - 176 oF) 

pH: Not Detennined 

Pereent Volatile: Negligible. 

10. STABILITY AND REACTMTX 


StabiUty: Stable. 


IncompaUbiUty: Stronl oxidizinl aacnts. 


Hazardous Decomposition Products: Carbon monoxide. carbon dioxide. aldehydes. nitroacn oxides. 


Hazardous Polymerization: Will not occur. 


11. TOXICOLOGICAL INFORMATION 


Acute Oral Elfedl (LD50): Not evaluated. 


Acute Dermal ToDdty (LD50): Not evaluated. 


Inbalatlon ToDdty (LC50): Not evaluated. 


SensitIzation: Potential sensitizer. 


SkID Irritation: Not evaluated. 


Eye Irritation: Not evaluated. 


Cbronle Exposure Elfedl: Not evaluated. 


12. ECOLOGICAL INFORMATION 


AdditloDallnformatlon: No ccoloaica1 information available. 


13. DISPOSAL CONSIDERATIONS 


Waste Disposal Method: Dispose in accordance with federal. state and local regulations. 


11. TRANSPORT INFORMATION 

Department of Transportation: Not regulated. 


Printed: 411512002 Pale30f 4 


16 
RD1Q00.40 Vutico Inc. 

Effective Date: 4/3102 Polymer Spedalties 

15. REGULATORY INf08MATION 

US Federal Regulations: 

Occupational Safety and Health Act (OSHA): This Material Safety Data Sheet (MSDS) has been prepared in compliance with 

the federal OSHA Hazard Communication Standard 29 CPR 1910.1200. This product is not considered to be a hazardous chemical 

under that standard. 

Resource CODSe"ation and Recovery Act (RCRA): Not a hazardous waste under RCRA (40 CPR 261). 

TSCA Seetion 8(b) • Inventory Status: This chemical substance is not included on the TSCA Inventory and is transmitted to you 

solely for research and development purposes and may not be used, processed or distributed for a commercial purpose. In 

accordance with 40 CPR 720.36 of the Premanufacture Notification rule. this substance may only be used by. or directly under the 

supervision of. technically qualified individuals. 

16. OTHER INF08MATION 

MSDSNo: 1207' 

Prepared By: M. Slattery 

Approved By: James E. Mumby 

Title: Director. Product Safety 

Approved Date: 04103102 

Other Information: For further information. contact Product Safety personnel at (914) 78'·3000. 

Dlsdalmer: The following supercedes Buyer's documents. SELLER MAKES NO REPRESENT A TION OR WARRANTY. 

EXPRESS OR IMPLJED. INCLUDING OF MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE. No 

statements herein are to be construed as inducements to infringe any relevant patent. Under no circumstances shall Seller be liable 

for incidental. consequential or indirect damages for alleged negligence, breach of wamnty. strict liability. tort or contract arising in 

connection with the product(s). Buyer's sole remedy and Seller's sole liability for any claims shall be Buyer's purchase price. Data 

and results are based on controlled or lab work and must be confirmed by Buyer by testing for its intended conditions of use. The 

product(s) has not been tested for, and is therefore not recommended for, uses for which prolonged contact with mucous membranes, 

abraded skin. or blood is intended; or for uses for which implantation within the human body is intended. 

Printed: 411'12002 Page40f 4 

17 
INFRARED SPECTRUM 

.... o

.a. 

OeD 

CU-l 

I 

(I') •• 

...... c.. 

IDO

., •• CO 

CD c.. 

r-ICD 

~8 

u 


(f) 

o 


teen 

0& I

-'0 00 

(1')0

1(1')

a:. 

OJ ...... 


CD 

r-I 0. •• 

s CD 

CO N 

~U; 

Iq 

THERMOGRAVIMETRIC ANALYSIS t 

r CONFIDENTIAL l !


II __ 1"'\ 

20 

THERMOGRAVIMETRIC ANALYSIS 

CONFIDENT/AL 

21 

GEL PERMEATION CHROMATOGRAPH 

Ml111pore Corporatlon, Waters Chromatography Division 

34 Maple Street, Mllford, Massachusetts 01757 

22 

GEL PERMEATION CHROMATOGRAPH 

Ml11ipore Corporation, Waters Chromatograpny Division 

34 Maple Street, MIlford, Massachusetts 01757 

23 

GEL PERMEATION CHROMATOGRAPH 

Ml111pore Corporatlon, Waters Chromatography Dlvision 

34 Map1e Street, Milford, Massachusetts 01757 

2'1 

Gel Per~eation Chromato~raph 

1CI',-.-'oAW"". UUY/·...,,·"" ..... "''':''~-~. -- .... _-

daErf-"VAXUNE-'-"-GVC--Yf'~J~"r-T'IfF'''- , , 

1.15920 20-Mar';'12 2: 16t42 

;PC Sl1ce Table, continued 

25 

,. 

MASS SPECTROMETRIC ANALYSIS 

j Millennium Processing Report Page: 1 of 2 

'Report Method: Integration_Report Printed: July 11, 1990 

Processed: 11/07/90 10:38:04 Version: 2.10 

eIBA POLYMERS DIVISION RESINS LABORATORY 

,,­
27 

Study Title 

Test Substance Fox: RD 2000-040: Partition Coefficient (n-OctanoVWater) 


High Performance Liquid Chromatography (HPLC) Method 


Guidelines 

OECD Guideline for Testing ofChemicals, Section 1, Number 117 

U.S. EPA Product Properties Test Guidelines: OPPTS 830.7570 

Sponsor 

Vantico, Inc. 


281 Fields Lane 


Brewster, New York 10509 


Study Initiated 

March 14,2001 

Study Completed 

April 4 , 2002 

Authors 

Timothy J. Ward 


Charmaine C. Rondon 


Robert L. Boeri 


Testing Facility 

T.R Wilbury Laboratories, Inc. 


40 Doaks Lane 


Marblehead, Massachusetts 01945 


T.R. Wilbury Study Number 2175-VA Page lof 24 

28 

I. GOOD LABORATORY PRACflCE COMPLIANCE STATEMENT 

This study was conducted according to U.S. EPA FIFRA (40 CFR 160, 1993) and 

OECD Good Laboratory Practice Regulations. The stability of the test substance WIder test 

conditions was assumed but not verified at T.R. Wilbury Laboratories. Characterizations of 

the test substance and the reference substances were not performed in compliance with GLP 

rules. The balance used to weigh the sample container of the reference substance l,2,4­

trichlorobenzene before and after use was not calibrated (balances must be calibrated daily 

before use). The proper handling, storage, and distribution of the reference substances 

formamide and p-dichlorobenzene can not be verified based on the weight of the sample 

containers before and after use. Deviations from the study protocol are presented in Section 

xm oftbis report. 

Charmaine C. Rondon 

Study Director 

Sponsor 

Submitter 

T.R. Wilbury Study Number 2175-VA Page 2 of 24 

29 

Submitted by: 

Certification: 

" 

ll. QUALfIY ASSURANCE STATEMENT 

T.R Wilbury Laboratories, Inc. 

40 Doaks Lane 

Marblehead, Massachusetts 

T.R Wilbury Laboratories, Inc., study number 2175-VA, "Test Substance 

Fox: RD 2000-040: Partition Coefficient (n-OctanoVWater) High 

Perfonnance Liquid Chromatography (HPLC) Method," was audited by 

the Quality Assurance Unit for compliance with the protocol, standard 

operating procedures, and applicable Good Laboratory Practices (U.S. EPA, 

1993, OECD, 1997). Quality assurance audits were performed and the 

findings reported to T.R Wilbury Laboratories management and the study 

director on the following dates: 

Reported Reported 

Aspect Audit to Study to 

Audited Date Director Management 

Protocol: 12FEB01 12FEB01 12FEBOl 

In-life 15MAY01 18MAYOl 18MAYOl 

Raw DatalDraft Report llJUNOI BJUNOI llJUNOl 

Final Report: 04APR02 04APR02 04APR02 

Arthur P. Paradice, RQAP-GLP 

Quality Assurance Officer 

T .R. Wilbury Study Number 2175-V A Page 3 of 24 

30 

m. TABLE OF CONTENTS 


SECTION: PAGE 

I. Good Laboratory Practice Compliance Statement 2 


II. Quality Assurance Statement 3 


III. Table ofContents 4 


IV. Index ofTables and Figures 5 


V. Summary 6 


VI. General Information 7 


VII. Introduction 8 


vrn. Methods and Materials 8 


lX. Results and Discussion 11 


X. Conclusions 12 


" 

XI. References 22 


XII. Signature Page 23 


XIII. Protocol Deviations 24 


T.R. Wilbury Study Number 217S-VA Page 4 of 24 


31 

IV. INDEX OF TABLES AND FIGURES 


PAGE 


Table 1. Calculated log Pow values for the partition coefficient test 

(n-octanoVwater) with Fox. 

13 

Table 2. Chromatographic peak areas from the partition coefficient 

test (n-octanoVwater) with Fox. 

14 

Table 3. Temperature measured during the partition coefficient test 

(n-octanoVwater) with Fox. 

22 

Figure 1. Example chromatogram from the analysis of the test solution 

containing 39 mgIL (nominal) Fox prepared in mobile phase. 

15 

Figure 2. Example chromatogram from the analysis of the mixture of 

reference substances containing each component prepared in 

mobile phase. 

16 

Figure 3. Example chromatogram from the analysis of the mobile phase 

blank containing acetonitrile. 

17 

Figure 4. Example chromatogram from the analysis ofthe acetonitrile blank. 18 

Figure 5. Example chromatogram from the analysis of the forman).ide 

solution containing 96.0 mgIL (nominal) prepared in mobile phase. 

19 

Figure 6. Correlation graph for the eight reference substances used to 

determine the partition coefficient of Fox. 

20 

T.R. Wilbury Study Number 2175-VA Page 5 of 24 

32 

V. SUMMARY 

The determination of the n-octanoJ/water partition coefficient (Pow) of Fox is 

described in this report. The test was conducted for Vantico, Inc. on May 15, 2001, at 

T.R. Wilbury Laboratories in Marblehead, Massachusetts. It was conducted according to 

T .R. Wilbury Protocol Number 2175-V A. 

A preliminary test was conducted to provide an estimation of the run time to be 

used during the definitive test. This was accomplished by injecting a mixture of the 

reference substances in the HPLC system and recording the chromatogram for 30 

minutes. Thereafter, the solutions were injected in the following sequence: the mixture of 

reference substances, a blank (acetonitrile diluted 1: 10 with the mobile phase), the 

fonnamide solution, the test solution (in duplicate except during method validation), a 

blank (acetonitrile), the mixture of reference substances (reference substances were 

injected separately during method validation), and the fonnamide solution. The run time 

for all solutions was established at 30 minutes. 

The log Pow values for Fox, detectable with the chromatographic system used, 

were calculated as follows: 

Peak Number Retention Time log Pow 

T.R. Wilbury Study Number 2175-VA Page 6 of 24 

33 

VI. GENERAL INFORMATION 


Material Tested: 


Sponsor: 


Test Substance Shipped From: 


Purity: 


Study Initiation Date: 


Experimental Initiation 


Date: 


Experimental Termination 


Date: 


Study Completion Date: 


Fox: RD 2000-040 

Vantico, Inc. 

281 Fields Lane 

Brewster, New York 10509 

Vantico, Inc. 

281 Fields Lane 

Brewster, New York 10509 

Assumed to be 100% 

March 14,2001 (protocol signed) 

April 30, 2001 

May 24, 2001 

April 4, 2002 

T.R. Wilbury Study Number 217S-VA Page 7 of 24 

3'1 

YD. INTRODUCTION 

This study was sponsored by Vantico, Inc. The purpose of the study was to 

detennine the n-octanoVwater coefficient (Pow) of Fox, the ratio of the equilibrium 

concentrations of the test substance in a 2-phase system consisting of 2 largely 

immiscible solvents (n-octanol and water). The report contains sections that describe the 

methods and materials employed in the study and results of the investigation. The final 

report will be transferred to the sponsor for archiving and the raw data and a copy ofthe final 

report will be archived at T.R. Wilbury Laboratories for at least 10 years. 

VIll. METHODS AND MATERIALS 

TEST SUBSTANCE 

Fox (T.R. Wilbury Sample Number 1419) was delivered to T.R. Wilbury 

Laboratories on February 14, 200 1. It was contained in a 20 mL clear glass vial that was 

shipped in a cardboard box. The vial was labeled with the following infonnation: "Fox", 

The test substance (orange crystals) was shipped from Vantico, Inc., 281 Fields 

Lane, Brewster, New York 10509. Prior to use, the test substance was stored in the dark 

at room temperature. Based on infonnation supplied by the sponsor, the test substance is 

assumed to be 100% pure and stable under storage and exposure conditions. Unused test 

substance will be returned to the sponsor. 

REFERENCE SUBSTANCES 

Eight chemicals, obtained from commercial suppliers and for which the log Pow 

has been reported, were used to calibrate the elution time in units of log Pow. The mixture 

of reference substances consisted ofthe following: 

Reference Substance 

benzyl alcohol (J.T. Baker, 100%) 1.1 

toluene (J.T. Baker, 99.7%) 2.7 

p-dichlorobenzene (J.T. Baker, 99%) 3.4 

1,2,4-trichlorobenzene (E.M. Science, 99.63%) 4.2 

bibenzyl (Sigma Chemical Company, 99%) 4.8 

fluoranthene (Sigma Chemical Company, 99%) 4.7 

triphenylamine (Avocado Research Chemicals, 98%) 5.7 

2,4-DDT (Chern Service Inc., 99.4%) 6.2 

1 log Pow values according to the OECD guideline. 

T.R. Wilbury Study Number 2175-VA Page 8 of 24 
TEST PROCEDURES 

The study was perfonned according to the protocol for T.R Wilbury Study 

Number 2175~VA, "Test Substance Fox: Partition Coefficient (n~OctanollWater) High 

Perfonnance Liquid Chromatography (HPLC) Method". 

Solutions of the reference substances, excluding fonnamide, were prepared in 

acetonitrile (Burdick & Jackson, lot # CB 620) at a concentration of 760 to 870 mgIL. A 

mixture of the reference substances was prepared by adding a 500 aliquot of each 

solution (78 mgIL benzyl alcohol, 83 mgIL toluene, 87 mgIL p~dichlorobenzene, 

84 mgIL 1,2,4-Trichlorobenzene, 76 mgIL bibenzyl, 76 mgIL fluoranthene, 76 mgIL 

triphenylamine, and 78 mgIL 2,4~DDT) to a 5.0 mL class A volumetric flask and 

bringing the total volume to 5.0 mL with mobile phase (methanollHPLC water; 75/25; 

v/v). For the detennination of to (dead time or the average time it takes for an unretained 

solvent molecule to pass through the column), a solution of fonnamide (E.M. Science. 

lot# FX0420~8) was prepared in acetonitrile at a concentration of 96 mgIL by adding a 

500 J.1L aliquot of solution to a 5.0 mL class A volumetric flask and bringing the total 

volume to 5.0 mL with mobile phase. 

A stock solution of Fox with a nominal concentration of 390 mgIL was prepared 

by bringing 0.0098 g of test substance to a total volume of 25 mL with acetonitrile. The 

stock solution was diluted by adding a 500 aliquot of solution to a 5.0 mL class A 

volumetric flask and bringing the total volume to 5.0 mL with mobile phase. 

For a preliminary estimation of the run time, the mixture of reference substances 

was injected in the HPLC system and was recorded for 30 minutes. Thereafter, the 

solutj.pns were injected in the following sequence: the mixture of reference substances, a 

blank (acetonitrile diluted 1:10 with the mobile phase), the fonnamide solution, the test 

solution (in duplicate except during method validation), a blank (acetonitrile), the 

mixture of reference substances (reference substances were injected separately during 

method validation), and the fonnamide solution. The run time for all solutions was 

established at 30 minutes. The temperature in a flask of deionized water next to the 

mobile phase was recorded several times during the analysis (thennometer 125). 

ANALYTICAL METHOD 

Samples were analyzed using a Hewlett Packard Series 1100 HPLC equipped with 

a diode arraylUV detector set at 230 nm and a 10 nm bandwidth. Typical instrumental 

conditions were: 

Column: Zorbax SB~C8 (4.6 mm x 150 mm), 5J.1ffi at 25°C 

Column flow: 1.0 mUminute 

Total run time: 30 minutes 

Injection size: 50 ~ 

Mobile phase: 75:25 (v:v) methanol:HPLC grade water 

Flow program: Isocratic. 

T.R Wilbury Study Number 2175-VA Page 9 of 24 

36 

The analytical method was validated prior to the start of the definitive test. Method 

validation samples consisting of the mixture of reference substances, a blank (acetonitrile 

diluted 1: 10 with the mobile phase), the formamide solution, the test solution, a blank 

(acetonitrile), the eight individual reference substances, the mixture of reference substances, 

and the formamide solution were injected to establish the retention time order. 

CALCULATIONS 

The capacity factor (k') was determined for each reference substance and the test 

substance using the following equation: 

tR- to 


k' = 


where: 

tR = test/reference substance retention time 

to = the dead time [the average time it takes for an unretained solvent 

molecule (formamide) to pass through the column]. 

A linear regression plot of the log k' for the reference substances vs. log Pow 

values of the reference substances was used to determine the log Pow for each peak 

identified in the test substance (R2 = 0.9938). A comparison of the log k values for the 

test substance with the log k values of the reference substances was used to determine the 

log Pow for the test substance according to the following regression equation: 

" 

y = 0.2919x - 0.9174 

where: 

y = log k' for the test substance 


x = log P ow for the test substance 


T.R. Wilbury Study Number 2175-VA Page 10 of 24 

37 

IX. RESULTS AND DISCUSSION 

Representative HPLC chromatograms of the test solution, the mixture of 

reference substances, the blanks (acetonitrile diluted with mobile phase), and the 

formamide solution are presented in Figures 1 to 5. The to was determined to be 1.630 

minutes with a mean value of both measurements (1.629 and 1.631 minutes). The mean 

values of the retention times, k' values, log k' values, and log Pow values are summarized 

in Table 1 and the correlation graph for the eight reference substances is presented in 

Figure 6. Chromatographic peak areas are presented in Table 2. The temperature of the 

area surrounding the mobile phase was 24°C during the analysis (Table 3). 

The log P _ values for Fox, detectable with the chromatographic system used and 

reported using the mean ofdata from duplicate injections, were calculated as follows: 

Peak Number Retention Time 

The log Pow values calculated individually for each duplicate injec.tion were identical for 

each peak. 

Components of Fox with retention times less than 1.5 to 2.0 minutes, and log Pow 

values below 1.5 would generally be considered hydrophilic and unlikely to be 

significantly accumulated in organisms (Ran~ 1995). Components with log Pow values 

above 6.0 are generally considered to be superhydrophobic and readily accumulated, but 

their accumulation can be mitigated by the large size of these molecules. Compounds 

with log P _ values between 1.5 and 6.0 generally accumulate, but the accumulation of 

individual components of Fox that fall within this log P _ range would need to be 

evaluated individually for bioaccumulation because factors such as uptake and 

depuration kinetics, and metabolism could affect accumulation in organisms. 

T.R Wilbury Study Number 2175-V A Page II of 24 

38 

X. CONCLUSIONS 

Fourteen individual peaks were identified on duplicate chromatograms produced 

by HPLC analysis of Fox. The retention times of these peaks were compared to the 

retention times of eight reference substances with known log Pow values. The calculated 

log Pow values for the fourteen peaks identified in the sample of Fox were [ ]

( J 

CONF\DENT\~L 

T.R. Wilbury Study Number 217S-VA Page 12 of 24 

3<1 

Table 1. Calculated log Pow values for the partition coefficient test (n-octanoUwater) 

with Fox. 

Substance ~l k' logk' 

Reference Substance 

Benzyl alcohol 2.003 0.229 -0.641 1.1 

Toluene 3.081 0.890 -0.051 2.7 

p-dichlorobenzene 3.642 1.234 0.091 3.4 

1,2,4-Trichlorobenzene 4.865 1.984 0.298 4.2 

Fluoranthene 5.913 2.628 0.420 4.7 

Bibenzyl 6.479 2.975 0.473 4.8 

Triphenylamine 10.528 5.459 0.737 5.7 

2,4-00T 14.792 8.075 0.907 6.2 

Test Substance 

Peak 1 

Peak 2 

Peak 3 

Peak 4 

Peak 5 

Peak 6 

Peak 7 

Peak 8 

Peak'!) 

Peak 10 

Peak 11 

Peak 12 

Peak 13 

Peak 14 

1 Mean value ofthe retention times ofthe two reference substance or test substance 

chromatograms. 

2 Reference substance log Pow values according to the OECO guideline. 

T.R. Wilbury Study Number 2175-VA Page 13 of 24 

'-10 

Table 2. Chromatographic peak areas from the partition coefficient test 

(n-octanol/water) with Fox. 

Area 

Mean 

Retention Time Replicate 1 Replicate 2 Mean 

T.R. Wilbury Study Number 2175-V A Page 14 of 24 


41 

CONFIDENTIAL 
 DADI A. Sig:23O.10 Ref=ofl (J:IHPCHEMlIIOATAI2175\005-0501,O) 

mAU 

175 

150 

125 

100 

7S 

50 

2S 

5 10 15 20 m' 

o CO 

, 

Figure 1. 	 Example chromatogram from the analysis of the test solution containing 

39 mgIL (nominal) Fox prepared in mobile phase 

T.R. Wilbury Study Number 2175-VA 	 Page 15 of 24 

42 

DADl A. SIgoo230.1 0 (J:IHPCHEMl1IOATAI21751OO2-0201.0) 

rnAU 

300 

250 ! 200 ii 150 ... 100 


50 
 ;! II 8 ;; 

g ~! 1... "= 0 ,..: '---'!!'r~·L\ I

0 $ 10 15 20 m' 

Figure 2. Example chromatogram from the analysis of the mixture of reference 

substances containing each component prepared in mobile phase. 

T.R. Wilbury Study Number 2175-VA Page 16 of 24 

43 

4 

2 

CADl A. S9"~.III.l II 1'(""'" (J:IHPCHEMll\OATA121751OO3-0301.CI 

mAU 

a 

·2 

0 

\~ 

5 10 15 20 25 ",.,j 

Figure 3. Example chromatogram from the analysis of the mobile phase blank 

, ' containing acetonitrile. 

T.R. Wilbury Study Number 2175·YA Page 17 of 24 
OAOI A. Slril-230.10 R.r-.:o«(J:IHPCH~'1DAT"I2175\OO1-4701.0) 

mAU - & 


4 


2 


oH 

-2 

-4 

0 5 10 ,'5 20 2S mit 

~igure 4. Example chromatogram from the analysis ofthe acetonitrile blank. , 

T.R. Wilbury Study Number 2175-VA Page 18 of 24 

45 

CONFIDENTIAL 


OADI A. Slga230.10 RtIPaII (J:lHf'CHEMl1\OATA1217511)09.011C)1 ,0) 

rMU 

30 


25 


20 


15 


10 


5 


Or-, 

o 

Figure S. Example chromatogram from the analysis of the formamide solution 

containing 96.0 mgIL (nominal) prepared in mobile phase. 

T.R. Wilbury Study Number 2175·V A Page 19 of 24 

46 

1 

0.8 

0.6 

0.4 

0.2 

::li.I 

00 

.3 0 

-0.2 

-0.4 

-0.6 

-0.8 

y" 0.2919x· 0.9174 

R2 =0.9938 

• 

, . 0 1 2 3 4 

Log Pow 

5 6 7 

Figure 6. Correlation graph for the eight reference substances. used to determine the 

partition coefficient of Fox. 

T.R. Wilbury Study Number 217S-VA Page 20 of 24 

'-/7 

Table 3. Temperature measured during the partition coefficient test (n-octanoVwater) 

with Fox. 

Time Temperature (OC) 

1450 24 


1500 24 


1540 24 


1550 24 


1610 24 


1622 24 


T.R. Wilbury Study Number 2175-V A Page 21 of 24 

XI. REFERENCES 


OECD. 1997. OECD Principles of Good Laboratory Practice. [C(91) 1861 Final]. 

OECD Guidelines for Testing Chemicals. 1989. Section 1. No. 117. Partition Coefficient 

(n-OctanollWater), High Performance Liquid Chromatography (HPLC) Method. 

Adopted March 30, 1989. 

Rand, G.M., 1995. Fundamentals of Aquatic Toxicology: Effects, Environmental Fate, 

and Risk Assessment. Second Edition. Taylor and Francis, Bristol, PA. 1125 pp. 

U.S. EPA. 1993. 40 CFR Part 160. 	 Federal Insecticide, Fungicide, and Rodenticide Act 

(FIFRA); Good Laboratory Practice Standards. Code of Federal Regulations, 

Title 40 Part 160. 

U.S. EPA. 	 1996. Product Properties Test Guidelines. OPPTS 830.7570. Partition 

Coefficient (n-OctanollWater) Estimation by Ljquid Chromatography. EPA 712­

C-96-040. 

T.R. Wilbury Study Number 2175-VA 	 Page 22 of 24 

'-19 

XII. SIGNATURE PAGE 


Channaine C. Rondon Date 

Study Director and Coauthor 

h(1i~~ Ka~ Dlstelbrink 

Analytical Chemist 

Robert L. Boeri Date 

Coauthor 

T~~ar Date 

Au or 

T.R Wilbury Study Number 217S-VA Page 23 of 24 

5() 

Xlll. PROTOCOL DEVIATIONS 

No protocol deviations occurred during this study. 

, 

, 

T.R. Wilbury Study Number 217S-V A Page 24 of 24 

S1