Bicarbonates 

073505, 073508

Product Chemistry—Registration Review

UNITED STATES ENVIRONMENTAL PROTECTION AGENCY

MEMORANDUM

SUBJECT: Product Chemistry Scoping Document for the Registration Review o

Bicarbonates (Sodium, Potassium)

Registration Review Case #:

PC Code:

CAS Numbers:

Chemical Class:

FROM: Leonard Cole, Senior Regulatory Specialist

Biochemical Pesticides Branch

Biopesticides & Pollution Prevention Division (7511P) 

TO: Linda Hollis, Chief

Biochemical Pesticides Branch

Biopesticides & Pollution Prevention Division (7511P) 

ACTION REQUESTED

The following scoping document contains the product chemistry assessment for 

sodium bicarbonate and potassium bicarbonate

Review Preliminary Work Plan.

Executive Summary

Registration Review

UNITED STATES ENVIRONMENTAL PROTECTION AGENCY

WASHINGTON, D.C. 20460

May 23, 2012

OFFICE OF CHEMICAL SAFETY AND POLLUTION PREVENTION

Product Chemistry Scoping Document for the Registration Review o

(Sodium, Potassium). 

Registration Review Case #: 4048

073505, 073508

144-55-8, 298-14-

Biochemical

Leonard Cole, Senior Regulatory Specialist

Biochemical Pesticides Branch

Pollution Prevention Division (7511P) 

Linda Hollis, Chief

Biochemical Pesticides Branch

Biopesticides & Pollution Prevention Division (7511P) 

The following scoping document contains the product chemistry assessment for 

sodium bicarbonate and potassium bicarbonatein support of the development of the Registration 

Case #: 4048

OFFICE OF CHEMICAL SAFETY AND POLLUTION PREVENTION

Product Chemistry Scoping Document for the Registration Review of 

-6

The following scoping document contains the product chemistry assessment for the biopesticides 

in support of the development of the Registration 
Bicarbonates CAS #s 144-55-8, 298-14-6 

073505, 073508

The Agency has made the determination that for the purposes of registration review, there 

is adequate information available on bicarbonates, (including sodium and potassium), and 

does not foresee the need for additional biochemical pesticide product chemistry data for 

products that currently contain the three bicarbonates outlined above as the technical 

grade active ingredient. 

Introduction

The bicarbonates (sodium and potassium) are naturally occurring compounds that are not 

expected to have adverse effects on humans or the environment when used as fungicides. Use of 

these two compounds in pesticide products may provide an alternative to more toxic fungicides 

currently on the market.

The active ingredients were first registered in 1994 for use as a fungicide (Potassium bicarbonate 

and Sodium and Fact Sheet, 1999). There are currently 8 products registered containing the 

active ingredient, Potassium bicarbonate, and one technical grade active ingredient (TGAI) 

Sodium bicarbonate. Both bicarbonates are approved for use as inert ingredients in pesticide 

formulations.

Product Chemistry Summary

Concerning the product chemistry of the bicarbonates, all biochemical pesticide data 

requirements for the technical grade active ingredients have been satisfied and are 

summarized in Tables 3 and 4. While no further product chemistry data are necessary for 

the products currently registered, future registrations must adequately address all of the 

biochemical pesticides product chemistry data requirements.

Table 1. Product Identity and Composition for Sodium bicarbonate

Chemical Name, IUPAC Sodium bicarbonate
Bicarbonates

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Molecular Weight

PC Code

CAS Registry Number

Common Name

Molecular Formula

Registration Review Case Number

Chemical Structure

CAS #s 

105.9784 g/mol

073505

144-55-8

Baking soda, bicarbonate of soda 

NaHCO3

Registration Review Case Number 4048

s 144-55-8, 298-14-6 

3
Bicarbonates

073505, 073508

The Agency has conducted a review of the 

Sodium bicarbonate and Potassium bicarbonate

Table 3. Biochemical Pesticides Product Che

bicarbonate

Guideline 

No.

Physical and Chem

Properties

830.1100 Product Identity and 

Composition

830.1200 Description of starting 

materials, production and 

formulation process

830.1400 Discussion of formation 

of impurities

Chemical Name, IUPAC

Molecular Weight

PC Code

CAS Registry Number

Common Name

Molecular Formula

Registration Review Case Number

Chemical Structure

CAS #s 

The Agency has conducted a review of the available product chemistry data and information

Sodium bicarbonate and Potassium bicarbonate. These data are summarized below.

. Biochemical Pesticides Product Chemistry Data Requirements for 

Physical and Chemical 

Properties

Status1 Value

Product Identity and A Refer to Table 1.

Description of starting 

materials, production and 

formulation process

A CBI

Discussion of formation A CBI

Potassium bicarbonate

100.115 g/mol

073508

298-14-6

Potassium bicarbonate

K2CO3

Registration Review Case Number 4048

s 144-55-8, 298-14-6 

4

available product chemistry data and information for 

. These data are summarized below.

Sodium 

MRID

00019705

00019706

00019707

43297201

43463101

43463102

00019712

43297201

43463103

43463200

43463201

43463202

43463203

00012547
Bicarbonates CAS #s 144-55-8, 298-14-6 

073505, 073508

5

830.1700 Preliminary analysis A CBI 43463200

43463201

43463202

43463203

830.6302 Color A White crystalline 00019705

00019706

43463101

43463102

830.6303 Physical state A powder 00019705

00019706

43463101

43463102

830.6304 Odor A No characteristic odor 43297201

43463101

43463102

830.6313 Stability to normal and 

elevated temperatures, 

metals and metal ions

A Stable to heat and light 00019706

43463101

43463102

830.7000 pH A 8.3 00019705

00019706

00019707

830.7050 UV/Visible light 

absorption

N/A

830.7200 Melting point/melting 

range

A 60C (140F) 00019705

00019706

00019707

43297201

830.7220 Boiling point/boiling 

range

N/A

830.7300 Density A 2.2 43463101

43463102

830.7520 Particle size, fiber length, 

and diameter distribution

N/A Not applicable; 

chemical is not water 

insoluble and fibrous 

with a diameter ≥ 0.1μm
Bicarbonates CAS #s 144-55-8, 298-14-6 

073505, 073508

6

830.7550

830.7560

830.7570

Partition coefficient (nOctanol/Water)A

Log P = 4.320

ChemIDpl

us Lite

(2012)

830.7840 Water solubility A 8.6 g/100 ml @ 20 C 

(68 F)

41614403

42501002

830.7950 Vapor pressure N/A 00019707

43297201

43463101

43463102

1. A=Acceptable. N/A=Not Applicable. N/D=Not Determined.

Table 4. Product Identity and Composition for Potassium bicarbonate

Guideline 

No.

Physical and Chemical 

Properties

Status1 Value MRID

830.1100 Product Identity and 

Composition

A Refer to Table 2. 44092500

44092501

44092502

44092503

45444902

830.1200 Description of starting 

materials, production and 

formulation process

A CBI 46026701

48777500

48777501

48777502

830.1400 Discussion of formation 

of impurities

A CBI 44326202

46026701

830.1700 Preliminary analysis A CBI 45444901

830.6302 Color A White crystalline 44092502

44092503

45444902

830.6303 Physical state A powder 46026701

830.6304 Odor A No characteristic odor 45444902

830.6313 Stability to normal and 

elevated temperatures, 

metals and metal ions

A Stable to heat and light 44092502

44092503

830.7000 pH A 8.2 Lilly

MSDS
Bicarbonates CAS #s 144-55-8, 298-14-6 

073505, 073508

7

830.7050 UV/Visible light 

absorption

N/A 44092503

830.7200 Melting point/melting 

range

N/A

830.7220 Boiling point/boiling 

range

N/A

830.7300 Density A 2.2 44092502

44092503

830.7520 Particle size, fiber length, 

and diameter distribution

N/A Not applicable; 

chemical is not water 

insoluble and fibrous 

with a diameter ≥ 0.1μm

830.7550

830.7560

830.7570

Partition coefficient (nOctanol/Water)A

Log P = 4.320

ChemIDpl

us Lite

(2012)

830.7840 Water solubility A 8.6 g/100 ml @ 20 C 

(68 F)

41614403

42501002

830.7950 Vapor pressure N/A 00019707

43297201

43463101

43463102

References

Merck Index, Online. 01/24/2012.

US EPA Sodium and Potassium bicarbonate Fact Sheet (1999)

 http://www.epa.gov/oppbppd1/biopesticides/ingredients/factsheets/factsheet_073508.htm