### UN ITED STATES ENVIRONMENTAL PRO TEC TION AGENCY

WASHfNGTON

, D.C. 20460

OFFICE OF CEMICAL SAFETY AND

POLLUTIO N PREVENTION



### PC Code: 080302

DP B arcode: 421927



### Apr il 15

, 2015



### MEMORANDUM

SUB .J EC T: Ecolog i cal Risk Assessme nt for Proposed Sec ti on 3 New Uses for Fluopyram on Artichoke, Vegetab l es (Brassica

. bulb, cucurbi t s, fruiting

, leaf y, legumes and

root/t ub erous / corm), Ca rr ot, Cerea l gra in s, C it rus, Cotton

, Ginseng, Grapes

, S m a ll vines fruits

, grasses (forage / feed / seed), H e rb s, H o p s, Soybea n

, Oil seed

gro up

, Ornamentals, P ea nut

, P o m e fruit s, P o t a t o

, Small b e rri es, S t o n e fruit

, Strawbe rr y and o th e r l ow-growi n g berries

, S u garbeet, Tr ee nut s a nd Turf



### TO:

FROM: Driss Benmhend

, Ri s k Manager R ev i ewe r

S h aja Joyner

, Risk Manager 20

F un g icid e Branch

Re g i s tr a ti o n Division ( PRO ) (7505 P)

Geoffrey Sinclair, Ph .D., Bi ologist**~** 

### r-...

## J~~==~**\>S;~ ~~~**  Mohammed Ruhm an, Ph

. D

., Senior Agrono mi st 

## ff--Z

....... Env i ronmen t al Risk B ranch 

# v o4/ IS) 

## IS

E n v ir o nm e nt a l Fate and Effec t s Di v i s ion (7507P) 

# 'f/ 

# !S/!S"

THROUGH: Mah S h am im

, Ph.D

., Br a n ch C hi ef

Environmental Risk Branch V I

Environmenta l Fate and Effects Di v i s i on (7507 P )

Thi s m e m o co nt a in s th e findings of a Section 3 New Use Ecolog i cal Ri sk Assessment for e l eve n

n ew o r amen d e d l a bel s that cover see d tr eatme nt for cotton, soy b ea n and peanuts, and so il /fo li a r

app li ca ti ons by grou nd / ai r / ai r blast/chemigation for many crops and fo liar / drench a ppli cat i ons by
ground / chemigation for turf and ornamentals. The eleven new or 

### amend ed labels are for product s

with formulat i ons containin g fl uopyram alone and fo nnul atio n s con t a inin g fluopyram wit h other

active in g r e dients. Fluopyram i s a fu n gicide and c urr e nt fo rmul at i o n s for fluopyram includ e

s u spe n s i o n concentrates fo r th e c h e mical a l o n e (4 1 .5% a.i)

, o r w ith other fungic id es includin g

tebucona zo l e, trifloxystrobin

, pyrimethanil

, o r pr o thioc o n azo l e. Fluopyram and / or its mixtur es

have agricu ltur a l uses on app l es

, water m e l o n s, se l ected dry beans

, gra p es (wi n e)

, peanuts,

po t atoes

, strawb erries

, sugar bee t

, a nd tree nuts applied by gro un d

, ai r b l ast, and ae r ial spray int o foliage and seed treatments for cotton, soybean and peanut s. f' l uopy ran 1 i s a fungic i de to pre ve nt

### 2

and/or control fungal diseases

. The biochemical mode of action of this chemical involves the inhibition of the enzyme succinate dehydrogenase within the fungal mitochondrial respiratory chain, thus blocking electron transport. Risk associated with the proposed new uses of fluopyram are confined primarily to terrestrial taxa. For spray applications there was chronic dietary based risk from consumption of all dietary categories but the fruit/pods/seeds category. Spray applications also resulted in chronic dosed

- based risk to mammalian ta xa in every size class for short grass for most dietary items for small and medium sized mammals. Exposure to Fluopyram via seed treatments potentially poses a cute risk to small and medium sized endangered avian and mammalian species

. There was chronic ri sk indicated for both avian and

mammalian taxa from all seed treatments.



# I. Previous Use Patterns a nd Ecological Risk Assessments

Two ecological risk assessment s were cond ucted previously. The first assessment was for a
S ection 3 new chemical registration of fluopyram ( DP Barcode D353315, 369756, and 385637,
dated 8/29/11) . This assessment covered the following crops: Apples, Beans (dry), Cherries, Cucurbits, Grapes (wine), Peanut, Potato, Stone Fruits, Strawberry , Sugar beet, and Tree Nuts.

The second assessment (DP Barcode 414232 dated June 25, 2014 ) was for Fluopyram New Uses

on cotton “in

- furrow and seed treatment”, Soybeans “seed treatment” and Peanuts “ in

- furrow and foliar applications

.

The results of the first assessment (DP Barcode D3 53315, 369756, and 385637) suggest ed the potential for chronic risk to non

- target mammals, birds, reptiles and terrestrial

- phase amphibians based on modeled exposure resulting from spray applications of fluopyram. RQs for acute exposure were not calculate d in the previous risk assessment due to non

- definitive endpoints that were higher than the highest concentrations tested. Because of this, the author of previous assessment presumed l ow acute risk concerns (at levels below the levels of concern) exist for mammals, birds, reptiles and terrestrial

- phase amphibians. An addendum was submitted to the Environmental Fate and Ecological Risk Assessment for Fluopyram Registration to correct the endpoints and risk quotients reported for the mammalian toxicity studi es (DP Barcode: 396805).

The corrected calculations still indicate d chronic risk concerns using dose

- based RQs, although a noticeable shift in magnitude occurs. All dietary

- based RQs are below the level

- of

- concern.

The second assessment for in

- furrow and seed treatment applications (DP Barcode 414232) showed low risk to aquatic organisms and terrestrial plants. Acute risk was indicated from both

seed treatments . S oybean s eed treatments may potentially adversely affect listed small avian taxa (20g weight class) on acute basis and cotton seed treatments may potentially adversely

affect both small and medium listed avian and mammalian taxa (20 g and 100 g for birds and 15 and 35g for mammals) on an acute basis. There was chronic risk indicated for both avian and

mammalian tax a from all four of the proposed new uses.

This assessment cons iders use patterns for eleven new labels ( Appendix I, Tables I

- 1 to I

- 11 ) which covers new and already registered crops (i.e., amendments to labels). In addition, this assessment uses the surface water concentration calculator (SWCC) for modeling exposure EECs for surface/pore waters and sediment resulting from all uses (current/amended plus new).

### 3



# II. Current/Amended and New Use Patterns

In previous ecological risk assessments, the following labels were considered:

1) Labels considered in the 1 st 

### assessment were for five labels: LUNA® PRIVILEG,

PROPULSE TM



### , LUNA ® 

### TRANQUILITY

, LUNA ® 

### EXPERIENCE, and LUNA®

SENSATION . These labels covered many crops at the time of registration of the new chemical fluopyram ; and

2) Labels considered in the 2 nd 

### assessment were for FluopyramST (EPA Reg. No. 264

- xxx)

and the amended label of Luna ® 

### Privilege (EPA Reg. No. 264

- 1078)

. FluopyramST label (a.i: fluopyram alone) covered use of fluopyram as a seed treatment for cotton (0.066 lb. a.i/A) and soybeans (0.138 lb. a.i/A). In contr ast, the amended Luna ® 

### Privilege (a.i: fluopyram alone) covered in

- furrow ground application for cotton at planting (0.222 lb. a.i/A) and in

- furrow plus ground/air foliar applications for peanuts (two applications at 0.22

lb. a.i. with 14

- day interval).

In this assessment, the proposed eleven new or amended labels cover seed treatment for peanuts and soil/foliar applications by ground/air/air blast/chemigation for many crops and foliar/drench applications by ground/chemigation for turf and ornamentals. Th e eleven new or amended labels are for products with formulations containing fluopyram alone and formulations containing fluopyram with other active ingredients. Table 1 contains a list of these products.

Table 1. List of the proposed products containing the active ingredient alone or with others

Item Product Name 1 Reg. No. Active Ingredient(s) Use Purpose



### 1 FLUOPYRAM 500

SC 432

-

xxxx Fluopyram alone Fungicide/Nematicide

In Turf & Ornamentals

2* LUNA®

PRIVILEGE 264

- 1078 Fluopyram alone

Fungicide

In Crops (refer to Appendix I, Tables I

1 to I

- 11 ) 3* PROPULSE TM 

### 264

- 1084 Fluopyram &

Prothioconazole

4* LUNA ®


### TRANQUILITY 264

- 1085 Fluopyram &

Pyrimethanil

5* LUNA ®



### EXPERIENCE 264

- 1091 Fluopyram &

Tebuconazole

6* LUNA®

SENSATION 264

- 1090 Fluopyram &

Trifloxystrobin 7

- 9 FLU+TFS SC

25/32.5/500 432

-

xxxx Fungicide/Nematicide

In Turf & Ornamentals 10 13ESP715 3.3 SC 432

-

xxxx Fluopyram alone

11 13ESP715 3.3 SC 432

-

xxxx Fluopyram alone Nematicide

In Turf & Ornamentals

1 

### for items 2*, 3*, 4*, 5*, and 6*: labels for these products are amended by mainly by adding more crops while items 1, 7, 8, 9, 10 and 11 are proposed new labels

### 4

A summary of important label information is included in Appendix I, Tables I

- 1 to I

- 11.



# III. Estimating Exposure EECs from Surface Water Sources

The Surface Water Concentration Calculator (SWCC) was used to calculate surface water EECs base on application/chemical parameters and crop representative scenarios ( Tables 2 and 3 ). Tier

II SWCC estimates pesticide concentrations in water bodies that result from pesticide applications to land. This model is designed to simulate the environmental concentration of a pesticide in the water column and sediment. The model uses PRZM version 5.0+ (PRZM5) and the Variable Volume Water Body Model (VVWM), replacing the older PE

- 5 shell, which used
linked PRZM3 (Carousel et al., 2005) and EXAMS (Burns, 2003). For more information about

the SWCC model refer to the EPA web 1



### .

Application parameters/scenarios

T he following steps were taken for modeling surface wa ter EEC s using the SWCC model:

(1) Extraction of modeling parameters: This was based (1) current labels with associated use patterns and (2) suggested new or amended labels with use patterns summarized in ( Appendix I, Tables I

- 1 to I

- 11 ). Extracted modeling parameters were for soil/foliar applications and seed treatment include: maximum single rates ( MSRs in Kg/ha), maximum number of applications ( MNAs ), maximum yearly application ( MYAs Kg/ha/year), and firs t application dates ( FADs ) in addition to the application procedure ( G = ground; A = aerial;

AB = air blast). It is noted that: (a) chemigation and drench were considered as ground applications to the soil and (b) seed treatments were considered as applicatio n to depths equal seeding depths of the crops;

(2) Assignment of crop scenarios to represent various use patterns; and

(3) Made sure to include various types of formulations containing fluopyram alone and mixtures in determining the highest application rates of the active ingredient fluopyram; the subject of

this memo.

Table 2 contains a summary of the extracted application parameters and scenarios for SWCC modeling which represent current and amended proposed labels for seed treatments of cotton, soybeans and peanuts.

Table 2. S ummary of modeled application parameters for flu opyram use as seed treatment

Application Type 1 Scenario 2 Application Rate (Kg/ha) MAI/F

AD
(Days) 4 AP

PR Crop Single 3 Total/Year Depth (cm) 4

Seed Treatment

STXcottonNMC 0.074

0.500 At
planting G 1.27

Cotton 5 1 st Foliar Application 0.250 153

A/G Surface

2 nd Foliar Application 0.176 160 Surface

1 URL: http://www.epa.gov/oppefed1/models/water/

### 5 Seed Treatment

MSsoybeanSTD 0.155

0.500 At
planting G 1.91

Soybeans 5 1 st Foliar Application 0.250 158

A/G Surface

2 nd Foliar Application 0.095 165 Surface

Seed Treatment

NCpeanutSTD 0.318

0.500 At
planting G 3.81

Peanuts 5 1 st Foliar Application None None

A/G Surface

2 nd Foliar Application 0.182 140 Surface

1 Assume planting with treated seeds followed by applying one or two foliar applications to the maximum yearly
application of 0.5 kg a.i/ha;

2 Crop scenario that gives the highest EDWC for the crop in question;

3 Assume seed treatment (for cotton= 0.074 Kg a.i/ha; for soybeans= 0.155 Kg a.i/ha; and for peanuts= 0.318 Kg a.i/ha)
followed by the 1 st application= the maximum single foliar applicati on for the crop and the 2 nd foliar application= 0.500
minus (seed treatment + 1 st application);

4 Depth (cm) = Minimum reported seeding depth; noting that this depth is variable depending on the geographic location
and climatic conditions where the crop is planted;

5 The application rates for seed treatments were calculated as follows: (1) For cotton : Rate= BEAD maximum seeding
rate of 85,000 seeds/A: Application Rate= 0.07716 X (85,000/100,000)= 0.066 lb. a.i /A (0.074 Kg/ha); (2) For soybean :

Rate= BEAD maximum seeding rate of 250,000 seeds/A: Application Rate= 0.07716 X (250,000/140,00)= 0.137786 lb a.i

/A; and (3) For peanuts : Rate= 0.124475 lbs a.i/100 lbs of seeds= 0.00124475 lb a.i/lb of seed; given that Lbs seed/A=
105,000 seeds/460= 228.261 lbs of seeds, the rate is equal to 0.00124475 lb a.i/lb of seed x 228.261 lbs seeds/A= 0.284

lbs a.i/A (r efer to amended LUNA® PRIVILEGE label). All seeding rates are based on the maximum seeding rate
published by BEAD.



### In modeling for applications that include seed treatments in cotton, soybean and peanuts, the application of seeds were @ depth (equal to seeding depth), followed by one or two foliar application(s) by air. Additionally, Table 3 contains a summary of the extracted application parameters and scenarios for SWCC modeling which represent current/amended/newly proposed labels for various crops an d turf and ornamentals.

Table 3 S ummary of modeled application parameters for fluopyram use on crops

Crop
Group Crop(s) Scenario MS

R MN

A MY

R MAI AP

- PR FADs

Artichoke Artichoke CARowCropRLF_V2 0.25 2 0.50 7 Air

And

Ground Due to the fact

that this chemical
may be applied
throughout the
growing season,

SWCC batch runs
were used by
applying the
pesticide over a
240 day time

window at 5

- day
steps starting the

1 st application at
14 days after Beans

& Peas Beans ILbeansNMC 0.20 2 0.40 7

MIbeansSTD 0.20 2 0.40 7

WAbeansNMC 0.20 2 0.40 7

Snap bean ORsnbeansSTD 0.19 2 0.38 10

Brassica
Vegetables Cabbage FLcabbageSTD 0.25 2 0.50 5

Cole crops CAColeCropRLF_V2 0.25 2 0.50 5

Bulb
Vegetables Onion CAonion_WirrigSTD 0.25 2 0.50 5

GAOnion_WirrigSTD 0.25 2 0.50 5

WAonionsNMC 0.25 2 0.50 5

Garlic CAGarlicRLF_V2 0.25 2 0.50 5

### 6

Canola Canola NDcanolaSTD 0.25 2 0.50 12 emergence and

the 2 nd application

at 14+th e application

interval. For
example,

artichoke:
CARowCropRLF

_V2 was run for
240 days at 5

- day
steps with the 1 st
application at 14
days after
emergence and

the 2 nd application
at 14+7= 21 days.

Maximum
EDWCs represent

results obtained
for the growing

seas on not the

240

- day time

window Carrot Carrot FLcarrotSTD 0.25 2 0.50 5

Cereal

Grains
Crops

And
Forage,

Fodder

or
Straw Corn CAcornOP 0.25 2 0.50 14

IAcornstd 0.25 2 0.50 14

ILCornSTD 0.25 2 0.50 14

INCornStd 0.25 2 0.50 14

KSCornStd 0.25 2 0.50 14

MNCornStd 0.25 2 0.50 14

MScornSTD 0.25 2 0.50 14

NCcornESTD 0.25 2 0.50 14

NCcornWOP 0.25 2 0.50 14

NDcornOP 0.25 2 0.50 14

NECornStd 0.25 2 0.50 14

OHCornSTD 0.25 2 0.50 14

PAcornSTD 0.25 2 0.50 14

STXcornNMC 0.25 2 0.50 14

TXcornOP 0.25 2 0.50 14

Sorghum KSsorghumSTD 0.25 2 0.50 14

TXsorghumOP 0.25 2 0.50 14

Sweet

Corn FLsweetcornOP 0.25 2 0.50 14

ORswcornOP 0.25 2 0.50 14

Wheat &
Barley CAWheatRLF 0.25 2 0.50 14

NDwheatSTD 0.25 2 0.50 14

ORwheatOP 0.25 2 0.50 14

TXwheatOP 0.25 2 0.50 14

Christmas

Trees Christmas

trees ORXmasTreeSTD 0.25 2 0.50 7 Ai rBlast

MSR= Maximum single rate (Kg/ha), MNA = Maximum number of applications,

MYA = Maximum yearly application (Kg/ha/year), AP

- PR = Application procedure, and the FAD (s)= First
application date(s)



### Table 2 (continued)

Crop Group Crop(s) Scenario MS

R MN

A MY

R MAI AP

- PR FADs

Citrus Citrus CAcitrus_WirrigSTD 0.25 2 0.50 7

Air Blast Same

As

Above FLcitrusSTD 0.25 2 0.50 7

STXgrapefruitNMC 0.25 2 0.50 7

Cotton cotton CAcotton_WirrigSTD 0.25 2 0.50 7

Air STXcottonNMC 0.25 2 0.50 7

### 7 TXcottonOP 0.25 2 0.50 7

And

Ground MScottonSTD 0.25 2 0.50 7

NCcottonSTD 0.25 2 0.50 7

Cucurbits Melons CAMelonsRLF 0.25 2 0.50 5

STXmelonNMC 0.25 2 0.50 5

MImelonStd 0.25 2 0.50 5

MOmelonStd 0.25 2 0.50 5

NJmelonStd 0.25 2 0.50 5

Cucumber FLcucumberSTD 0.25 2 0.50 5

Fruiting
Vegetables Peppers FLpeppersSTD 0.25 2 0.50 5

Tomato CAtomato_WirrigSTD 0.25 2 0.50 5

FLtomatoSTD_V2 0.25 2 0.50 5

PAtomatoSTD 0.25 2 0.50 5

All PAvegetableNMC 0.25 2 0.50 5

All STXvegetableNMC 0.25 2 0.50 5

Ginseng Ginseng MNsugarbeetSTD 0.25 2 0.50 5

Grapes &

Small Vine

Fruits Grapes CAWineGrapesRLF_V2 0.25 2 0.50 12

Air Blast CAgrapes_WirrigSTD 0.25 2 0.50 12

NYGrapesSTD 0.25 2 0.50 12

Grasses:
Forage/Seeds Hay CArangelandhayRLF_V2 0.25 2 0.50 14

Air

And

Ground Seeds ORgrassseedSTD 0.25 2 0.50 14

Herbs
& Spices Mustard CAColeCropRLF_V2 0.25 2 0.50 7

Dill weed ORmintSTD 0.25 2 0.50 7

Parsley/Celery CARowCropRLF_V2 0.25 2 0.50 7

Hops Hops ORhopsSTD 0.25 2 0.50 7

Leafy/ Petiole
Vegetables Lettuce/Spinach CAlettuceSTD 0.25 2 0.50 7

Celery CARowCropRLF_V2 0.25 2 0.50 7

Fennel CAonion_WirrigSTD 0.25 2 0.50 7

Legume
Vegetables Soybean MSsoybeanSTD 0.25 2 0.50 7

Snap bean ORsnbeansSTD 0.25 2 0.50 7

Ornamentals Residential CAresidential/imperviousRLF* 0.25 2 0.50 7 Ground March 15

MSR= Maximum single rate (Kg/ha), MNA = Maximum number of applications,

MYA = Maximum yearly application (Kg/ha/year), AP

- PR = Application procedure, and the FAD (s)= 1 st application date(s)
* For this run, used LA weather (W13970.dvf) with application to impervious surfaces (5% of the applied); drift= 0%

### 8

Table 2 (continued)

Crop Group Crop(s) Scenario MS

R MN

A MY

R MAI AP

- PR FADs

Ornamentals Nurseries CAnurserySTD_V2 0.25 2 0.50 5

Ground
(G)

Same

As

Above FLnurserySTD_V2 0.25 2 0.50 5

MInurserySTD_V2 0.25 2 0.50 5

NJnurserySTD_V2 0.25 2 0.50 5

ORnurserySTD_V2 0.25 2 0.50 5

TNnurserySTD_V2 0.25 2 0.50 5

Peanut Peanuts NCpeanutSTD 0.25 2 0.50 14 A & G

Pome Fruits Apples NCappleSTD 0.25 2 0.50 7

Air Blast

Apples ORappleSTD 0.25 2 0.50 7

Apples PAappleSTD_V2 0.25 2 0.50 7

Pear and
Quince WAorchardsNMC 0.25 2 0.50 7

CAfruit_WirrigSTD 0.25 2 0.50 7

Potato and

Tuberous &

Corm
Vegetables Potatoes CAPotatoRLF_V2 0.25 2 0.50 5

Air (A)

&

Ground FLpotatoNMC 0.25 2 0.50 5

IDNpotato_WirrigSTD 0.25 2 0.50 5

MEpotatoSTD 0.25 2 0.50 5

WApotatoNMC 0.25 2 0.50 5

Sweet Potato NCSweetPotatoSTD 0.25 2 0.50 5

Small

Berries Black/

Rasp Berries ORberriesOP 0.25 2 0.50 7

CAWineGrapesRLF_V2 0.25 2 0.50 7

Stone Fruits All CAfruit_WirrigSTD 0.25 2 0.50 5

Air Blast WAorchardsNMC 0.25 2 0.50 5

Peaches GAPeachesSTD 0.25 2 0.50 5

Cherries MICherriesSTD 0.25 2 0.50 5

Strawberry Strawberries CAStrawberrynonplasticRLF_V2 0.25 2 0.50 7

Air

&

Ground FLstrawberry_WirrigSTD 0.25 2 0.50 7

Sugar beet Sugar beet CAsugarbeet_WirrigOP 0.25 2 0.50 5

MNsugarbeetSTD 0.25 2 0.50 5

Sunflower Sunflower CAcornOP 0.25 2 0.50 14

Tree Nuts almonds CAalmond_WirrigSTD 0.25 2 0.50 7

Air Blast

Pecans GAPecansSTD 0.25 2 0.50 7

Tree nuts ORfilbertsSTD 0.25 2 0.50 7

Turf turf CATurfRLF 0.25 2 0.50 7

Ground FLturfSTD 0.25 2 0.50 7

### 9 PAturfSTD 0.25 2 0.50 7

MSR= Maximum single rate (Kg/ha), MNA = Maximum number of applications, MYA = Maximum yearly application
(Kg/ha/year), AP

- PR = Application procedure, and the FAD (s)= First application date(s)



### In modeling for the various crops, the application(s) was/were aerial/foliar applications for labeled crop use patterns that include both aerial and ground; aerial application is expected to give higher exposure. Crops labeled for ground or air blast applications were modeled as per the

labels.

Chemical and other parameters

No new fate and transport studies were submitted for fluopyram therefore the chemical parameters used for modeling were similar to all previous assessments and are summarized in

Table 4 . These parameters are as per the SWCC model input guidance 2

.

Table 4 Summary of SWCC input parameters for modeling fluopyram

Input Parameter (Unit) Value Reference (MRID No.)

Molecular Weight g/mole 396.72 Product chemistry

K

oc 

### (Average in L/Kg) 439 473723

- 01

Water Column Metabolism Half

- life
(days) 1,360

473723

- 11 Water Reference Temperature o 

### C 20

Benthic Metabolism Half

- life (days) 1,757

473723

- 12/13 Benthic Reference Temperature o 

### C 20

Aqueous Photolysis Half

- life (days) 57

473723

- 04 Photolysis Reference Latitude 40

Hydrolysis Half

- life (days) Stable= 0 473723

- 03/07

Aerobic Soil Half

- life (days) 464

473723

- 07 to 09 Soil Reference Temperature o 

### C 25

Vapor Pressure (VP in torr) 9.01 x 10

- 9



### Solubility in Water(mg/L) 16 Product chemistry

Henry’s Law Constant (unitless) 1.20 x 10

- 8 

### Calculated from VP

Air Diffusion Coefficient (cm 2 

### /day) 0.0

Heat of Henry (J/mol) 0.0 Product chemistry

Application rate and intervals Depends on the crop label Application Method

Application Efficiency 95% for aerial and 99% for ground

Spray Drift Fraction Aerial (0.125); Ground (0.062) and Airblast (0.042)



### Modeling results

Tier II SWCC results for modeled seed treatment are summarized in Table 5

.

2 SWCC model input guidance: URL: http://www.epa.gov/pesticides/science /efed/models/water/swcc/SWCC.pdf

### 10

Table 5. S ummary of modeled surface/pore waters and sediment EECs resulting from application of fluopyram as seed treatments (scenarios giving the highest EECs)

Crop Scenario Surface Water (ppb) Pore Water (ppb) Sediment (μg/Kg dry)

Peak 21

- day 60

- day Peak 21

- day Peak 21

- day



### Cotton STXcottonNMC 

### 19.6 19.8 18.10 16.5 16.5 295 295


### Soybeans MSsoybeanSTD 

### 15.8 15.5 15.20 14.7 14.7 263 263



### Peanuts NCpeanutSTD 

### 7.9 7.8 7.66 7.15 7.15 128 128



### Additionally, Tier II SWCC results for modeled crop uses are included in Table 6 . The results included are for the highest exposure EECs resulting from fluopyram application to various crop/crop groups; representative scenario giving the highest EEC for the crop/crop group are only

included.

Table 6 Highest EECs resulting from application of fluopyram to crops/crop groups

Crop Scenario (Giving the Highest EECs) Surface Water (ppb) Pore Water (ppb) Sediment (μg/Kg dry)

Peak 21

- day 60

- day Peak 21

- day Peak 21

- day

Artichoke Artichoke 21.6 21.3 21.0 19.9 19.9 356 356

Beans & Peas ILbeansNMC 47.8 47.0 46.2 44.4 44.4 795 795

Brassica Leafy Vegetables CAColeCropRLF_V2 37.3 36.7 36.0 34.6 34.6 619 619

Bulb Vegetables GAOnion_WirrigSTD 23.6 23.2 22.9 21.5 21.5 385 385

Canola NDcanolaSTD 31.5 31.1 30.9 30.3 30.3 542 542

Carrot FLcarrotSTD 40.2 38.3 36.4 33.0 32.6 591 584

Cereals: Corn and Sorghum MScornSTD & KSCornStd 50.1 49.3 48.2 46.4 46.4 831 831

Cereals: Wheat & others TXwheatOP 51.3 49.9 48.9 44.9 44.9 804 804

Christmas Trees ORX

- mass trees STD 6.9 6.8 6.7 6.4 6.4 115 115

Citrus FLcitrusSTD 20.6 20.2 19.4 17.4 17.4 311 311

Cotton STXcottonNMC & NCcottonSTD 31.7 30.7 30.5 29.8 29.8 533 533

Cucurbits STXmelonNMC & FLcucumberSTD 39.2 38.2 36.2 32.4 32.5 580 582

Fruiting Vegetables STXvegetableNMC & FLpeppersSTD 40.7 39.6 38.6 34.8 34.8 623 623

Ginseng MNsugarbeetSTD 34.1 33.7 33.3 32.2 32.2 576 576

Grapes & Small Vine Fruits NYGrapesSTD 19.6 19.4 19.2 19.0 19.0 340 340

Grasses for Forage/Seeds ORgrassseedSTD 21.4 21.0 20.6 19.4 19.4 347 347

Herbs & Spices CAColeCropRLF_V2 36.7 36.2 35.6 34.2 34.1 612 610

Hops ORhopsSTD 24.0 23.7 23.5 22.9 22.9 410 410

Leafy Vegetables + Petiole CAlettuceSTD 40.3 39.8 39.2 38.1 38.1 682 682

Legume Vegetables W/Soybeans MSsoybeanSTD 37.6 37.2 37.1 35.4 35.4 634 634

Ornamentals: Residential CAresidential/imperviousRLF 4.6 4.5 4.4 Not Determined (expect to be low )

Ornamentals: Nurseries MInurserySTD 29.6 29.3 29.4 28.4 28.4 508 508

Peanut NCpeanutSTD 32.4 32.0 31.6 30.1 29.8 539 533

Pome Fruits NCappleSTD 19.3 18.4 17.2 15.4 15.4 276 276

Potato, Tuberous/Corm Vegies MEpotatoSTD 50.2 49.9 49.6 49.0 49.0 877 877

### 11 Crop Scenario (Giving the Highest EECs) Surface Water (ppb) Pore Water (ppb) Sediment (μg/Kg dry)

Peak 21

- day 60

- day Peak 21

- day Peak 21

- day

Small Berries CAWineGrapesRLF_V2 13.3 13.4 13.1 12.5 12.5 224 224

Stone Fruits MICherriesSTD 20.2 20.0 19.7 19.5 19.5 349 349

Strawberry CAstrawberry

– non

- plasticRLF 40.7 40.0 39.1 36.4 36.3 652 650

Sugar beet MNsugarbeetSTD 34.1 33.7 33.3 32.2 32.2 576 576

Sunflower CAcornOP 18.1 17.8 17.6 16.9 16.9 303 303

Tree nuts GAPecansSTD 21.2 21.2 21.3 21.0 21.1 376 378

Turf PAturfSTD 16.5 16.2 15.8 15.6 15.6 279 279



# IV. Effects Summary

Table 7 shows the acute and chronic effects data that were used for estimating risk to aqua tic animals and plants.

Table 3. Toxicity reference values for aquatic organisms exposed to fluopyram technical or formulated fluopyram (Fluopyram SC 500A, 41.5% active ingredient).

Exposure

Scenario % Active

Ingredien t Species Exposure

Duration Toxicity

Reference

Value Reference

Classification

Freshwater Fish

Acute TGAI Rainbow Trout

96 hours LC 50 >1.78 mg

a.i./L MRID 47372328

94.70% Oncorhynchus

mykiss NOAEC=1.78 mg a.i./L Acceptable

TEP Rainbow Trout

96 hours LC 50 >46.4 mg a.i./L b MRID 47372333

41.50% Oncorhynchus

mykiss NOAEC=1.31 mg a.i./L Supplemental

Chronic TGAI

Fathead minnow Pimephales promelas 33 days NOAEC = 0.135 mg

a.i./L MRID 47372336

94.70% LOAEC = 0.269 mg

a.i./L Acceptable

Freshwater Invertebrates

Acute TGAI Water flea

48 hours EC 50 >17 mg

a.i./L MRID 47372324

94.70% Daphnia magna NOAEC=17 mg a.i./L Acceptable

TEP Water flea

48 hours EC 50 >38.2 mg

a.i./L MRID 47372325

41.50% Daphnia magna NOAEC=11.6 mg a.i./L Acceptable

### 12 Chronic TGAI Water flea

21 days NOAEC = 1214 μg a.i./L MRID 47372334

94.70% Daphnia magna LOAEC = 2996 μg a.i./L Acceptable

Estuarine/Marine Fish

Acute TGAI Sheepshead

minnow 96 hours LC 50 >0.98 mg a.i./L a MRID 47372330

94.70% Cyprinodon

variegatus NOAEC=0.98 mg a.i./L Acceptable

Chronic No Data

Estuarine/Marine Invertebrates

Acute TGAI Saltwater mysid
Americamysis

bahia 96 hours EC 50 >0.51 mg

a.i./L MRID 47372327

94.70% NOAEC=0.27 mg a.i./L Acceptable

Chronic No Data

Freshwater Benthic Invertebrates

Acute No Data

Chronic TGAI Midge

54 days Sediment

concentrations MRID 47372339

94.70% Chironomus tentans NOAEC = 26 mg a.i./kg

sediment Supplemental

LOAEC = 48 mg a.i./kg

sediment

Pore water

concentrations

NOAEC = 3.8 mg a.i./L pore

water

LOAEC = 8.8 mg a.i./L pore

water

Estuarine/Marine Benthic Invertebrates

Acute TGAI Saltwater amphipod

10 days Sediment

value: MRID 47372338

94.70% Leptocheirus

plumulosus LC50 > 100 mg a.i./kg

sediment Acceptable

### 13 NOAEC=100 mg a.i./kg

sediment

Pore water

value :

LC 50 > 7.5 mg a.i./L pore

water

NOAEC = 7.5 mg a.i./L pore

water

Chronic TGAI Saltwater amphipod

28 days Sediment

concentrations MRID 47372335

94.70% Leptocheirus

plumulosus NOAEC = 36 mg TRR/kg

sediment Supplemental

LOAEC = 92 mg TRR/kg

sediment

Pore water

concentrations

NOAEC = 2.5 mg TRR/L

pore water

LOAEC = 5.9 mg TRR/L

pore water

Aquatic Plants

TGAI

Pseudokirchneriella

subcapitata 96 hours EC 50 = 4.3 mg

a.i./L MRID 47372403

94.70% NOAEC = 1.46 mg a.i./L Acceptable

(biomass)

TEP

Pseudokirchneriella

subcapitata 72 hours EC 50 = 3.4 mg

a.i./L MRID 47372407

41.50% NOAEC = 1.17 mg a.i./L Acceptable

(cell density)

Fluopyram

lactame
(metabolite) Pseudokirchneriella

subcapitata 72 hours EC 50 >8.87 mg a.i./L MRID 47372418

### 14 94% NOAEC = 8.87 mg a.i./L Acceptable

(for both cell density and growth rate)

Macrophyte TGAI Duckweed

7 days EC 50 = 2.6 mg

a.i./L MRID 47372401

94.70% Lemna gibba NOAEC = 0.28 mg a.i./L Acce ptable

(frond number

based on yield)

TEP Duckweed

7 days EC 50 = 2.9 mg

a.i./L MRID 47372402

41.60% Lemna gibba NOAEC = 1.04 mg a.i./L Acceptable

(frond number

based on yield)

a These values were used for evaluation of risk via spray drift only.



### Table 8 shows the acute and chronic effects data that were used for estimating risk to terrestrial animals and plants.

Table 4. Toxicity reference values for terrestrial organisms exposed to fluop yram technical or formulated fluopyram (Fluopyram SC 500A, 41.5% active ingredient).

Exposure

Scenario % Active

Ingredient Species Exposure

Duration Toxicity

Reference

Reference

Value

Mammals

Acute TGAI Laboratory

Rat

Single oral

dose LD 50 > 2000

mg a.i./kg

bw MRID

(94.7% a.i.) ( Rattus

norvegicus ) 47372430

Acceptable

Chronic TGAI Laboratory
Rat ( Rattus
norvegicus ) 90

- day

dietary study NOAEL =

13 mg a.i./kg bw/day MRID

47372441

### 15 (94.7% a.i.)

LOAEL = 61 mg a.i./kg bw/day Acceptable

Birds

Acute TGAI

Northern bobwhite quail
( Colinus
virginianus )

and zebra

finch
( Taeniopygia

guttata ) Single oral

dose LD 50 >2000

mg a.i./kg

bw MRIDs

47372341

(94.5% a.i.
[bobwhite] and

94.7% a.i
[zebra finch]). Acceptable

and

47567007

Supplemental

Acute TGAI Northern bobwhite quail
( Colinus
virginianus ) 5

- Day

dietary LC 50 >4785

mg a.i./kg

diet MRID

47372343

(95.0% a.i.)

Acceptable

Chronic TGAI Bobwhite quail Avian

reproduction study (dietary

exposure,

one generation) NOAEC =

46.7 mg a.i./kg diet a MRIDs

47372344

(94.7% a.i.) ( Colinus

Virginianus )

and Mallard
duck ( Anas platyrhynchos ) Acceptable

LOAEC = 75.7 mg a.i./kg diet a 47372345

Supplemental

47372346

Acceptable

Terrestrial Insects

Acute TGAI Honey bee 96

- Hour

acute Contact

toxicity MRID

47372347

### 16 (95.5% a.i.) (Apis

mellifera ) contact and

oral toxicity

test LD 50 >100

μg test

material/bee Contact

toxicity test:

Acceptable

Oral toxicity

LC 50 >102.3

μg test

material/bee

Acute TEP Honey bee

96

- Hour

acute

contact and oral toxicity

test Contact

toxicity MRID

47372348

(41.6% a.i.) (Apis

mellifera ) LD 50 > 83.2 μg a.i./bee Contact

toxicity test:

Oral toxicity Acceptable

LC 50 > 89 μg

a.i./bee

Plants

- Tier I seedling emergence

Monocot TEP Oat ( Avena

sativa ), perennial

ryegrass ( Lolium

perenne ), barley
( Hordeum vulgare )

and corn ( Zea

mays ) Single

application

at test

initiation EC 25 >0.444

lbs a.i./A MRID

47372349

(41% a.i.) NOAEC =

0.444 lbs

a.i./A

Acceptable

Dicot TEP Sugarbeet ( Beta vulgaris ), oilseed

rape ( Brassica

napus ), soybean
( Glycine max ),

cucumber
( Cucumis sativus ),

buckwheat
( Fagopyrum

esculentum ) and

sunflower
( Helianthus

annuus ) Single

application

at test

initiation EC 25 <0.444

lbs a.i./A MRID

47372349

(41% a.i.) NOAEC

<0.444 lbs

a.i./A

Acceptable

Plants

- Tier II seedling emergence

Dicot TEP Buckwheat Full test EC 25 <0.444

lbs a.i./A MRID*

48934301

### 17 (42% a.i.) ( Fagopyrum

esculentum ) NOAEC

0.444 lbs

a.i./A Supplemental

Plants

- Tier I vegetative vigor

Monocot TEP Onion ( Allium

cepa ), oat ( Avena

sativa ), perennial

ryegrass ( Lolium

perenne ) and

corn ( Zea

mays ) Single

application

at test

initiation EC 25 >0.222

lbs a.i./A MRID

47372350

(41% a.i.) NOAEC =

0.222 lbs

a.i./A

Acceptable

Dicot TEP sugarbeet
( Beta vulgaris ), oilseed rape
( Brassica

napus ),

cucumber
( Cucumis

sativus ),

buckwheat
( Fagopyrum

esculentum ),
soybean
( Glycine max )

and sunflower
( Helianthus

annuus ) Single

application

at test

initiation EC 25 >0.222

lbs a.i./A MRID

(41% a.i.) NOAEC =

0.222 lbs

a.i./A 47372350

Acceptable



### *Bolded MRID indicates newly submitted study for this assessment.

In response to a supplemental study examining seedling emergence on the dicot buckwheat, an additional seedling emergence study was submitted (MRID 48934301). This study was

scientific ally sound but because this study only examined the dicot buckwheat it is considered supplemental. It does however fulfill th e guideline requirements when combined with the previously submitted seedling emergence study (MRID 47372349). At the application rates of 0.444 lb a.i. /A buckwheat had inhibitions in emergence and survival of up t o 5.4%; however

there was also a slight p romotion shoot length and overall no general trend was observed

. The

maximum i nhibition in dry weight was 1.9%, but was observed with promotion of dry weight as

well. T here was no effect in the negative control or any treatment group and the NOAEC was

es tablished as 0.444 lb a.i. / A.

### 18



# V. Risk Estimation

A. Risk Estimation for Aquatic Animals

Risks to aquatic animals from the proposed use of fluop y r am are summarized in Appendix 2

. For freshwater animals, no acute or chronic risks were identified either for listed or non

- listed species. Acute RQs for freshwater fish and invertebrates were all less than 0.03 and did not exceed the level of concern for either listed (LOC=0.1) or Nonlisted species (LOC=0.5).

C hronic fish RQs were all less than 0.36 and chronic invertebrate RQs were all less than 0.04,

and did not exceed the chronic LOC of 1.0. Acute RQs for estuarine/marine fish were all less

than 0.05 and did not exceed either listed or Nonlisted LOCs. Acute RQs for estuarine/marine

i nvertebrates ranged from <0.1 ( th ree crop groups: cereals (corn and sorghum), cereals (wheat and others), and Potato and tuberous/corm vegetables) to <0.01 and did not exceed either the

l isted species LOC (0.1) or the n onlisted s pecies LOC (0.5). No chronic toxicity data are

available for estuarine/marine invertebrates or fish. When possible the Agency uses t he acute to
chronic ratio (ACR) to bridge missing toxicity data in establishing potential risk to taxa with missing data. In this case establishing an ACR was not possible due to non

- definitive endpoints

in the taxa where data did exist. Chronic RQs for sediment invertebrates were all less than 0.03

and did not exceed the LOC of 1.0 for either freshwater or estuarine/marine invertebrates from either porewater or sediment exposure. Given the EECs that were generated from the modeled uses, it is reasonable to expect that aquatic animals are at low risk from the proposed uses which

is similar to the established uses covered in the previous as sessment on fluopyram ( US EPA

2011 )

.

B. Risk Estimation for Aquatic Plants

RQs for nonlisted species of both vascular and nonvascular plants were 0.02 or less and did not

exceed the LOC of 1.0. RQs for listed species of vascular and nonvascular plants also did not

exceed the LOC of 1.0. RQs for listed species of vascular aquatic plants ranged from 0.02 to 0.18 while RQs for listed nonvascular plants ranged from 0.01 to 0.04. These are consisten t with

the low risk determinations in previous assessments. The RQs are presen ted in Appendix 2

.

C. Risk Estimation for Terrestrial Animals

Risks to terrestrial animals were assessed for both spray applications as well as seed treatments.

In

- furrow applications were also assessed in the previous assessment.

Spray Applications

T errestrial EECs could be an underestimati on of actual exposure concentrations in the environment. Although the label stated that fluopyram can be applied via foliar spray application up to 2 times per season for the crops with the highest seasonal application rate (watermelons,
and strawberries), for this risk assessment, EFED assumed that fluopyram was applied at a

maximum of 2 times per year ( Table 9 ) . If there are conditions under which there is more than

### 19

one growing season for a crop within a single year, exposure estimates and risk to terres trial organisms could be significantly underestimated.

Table 9 . Input parameters used in T

- REX v1.4.1 to determine terrestrial EECs for the maximum fluopyram spray application scenario. a

Input Variable Parameter Value Source

Maximum application rate 0.2 5 lbs a.i./A

Maximum # of applications per year 2

Minimum application interval 5 days

Foliar half

- life 35 days T

- REX Default Value

a Representative of the maximum exposure scenario for all crop uses.



### The EECs on food items may be compared directly with dietary toxicity data or converted to an oral dose. For mammals, the residue concentration is converted to daily oral dose based on the fraction of body weight consumed daily as estimated through mammal ian allometric relationships. The screening

- level risk assessment for fluopyram considers upper

- bound predicted residues as the measure of exposure. Summaries of the predicted upper

- bound and mean residues of fluopyram that may be expected to occur on sele cted avian or mammalian food items immediately following application for the maximum use scenario are presented in Table

10

.

For the maximum fluopyram spray application scenario, acute concentrations on foliar surfaces ranged from 7 to 114 ppm for upper

- bound residues and 3 to 41 ppm for mean residues. These residues are very similar to those modeled in the 2011 assessment (DP Barcode: D352215) with maximum application rates of 0.222 lbs a.i./A.

Table 1 0

. Upper

- bound and mean terrestrial dietary EECs estimated for the maximum fluopyram spray application scenario (Kenaga values). a

Forage Type Upper

bound

Residues (ppm) Mean

Residues (ppm)

Short Grass 114 41

Tall Grass 52 17

Broadleaf plants 64 21

Fruits/pods/seeds 7 3

Arthropods 45 31

### 20

Spray Applications: Acute Risk to Birds and Mammals

Birds

Previous assessments did not calculate a cute dose

- or dietary

- based RQ s for birds because

definitive LD 50 

### and LC 50 

### values were not available. Utilization of the endpoint (LD50 > 2000 mg/kg bw; MRID 47372341) however indicate that the RQs would be less than 0.09 for the most conservative assumption using upper bound residues suggesting that there is low acute risk to birds from applications of fl uopyram at the maximum application rates.

Mammals

Previous assessments did not calculate a cute dose

- based RQ values for mammalian receptors because the results of the definitive submitted acute oral toxicity studies on mammals did not

allow calculation of a definitive LD 50 

### values. Utilization of the endpoint (LD50 > 2000 mg/kg
bw; MRID 47372430 ) however indicate that the RQs would be less than 0.0 2 for the most conservative assumption using upper bound residues suggesting that there is low acute risk to

mammals from applications of fluopyram at the maximum application rates.

Spray applications: Chronic Risk to Birds and Mammals

Birds For birds, chronic RQs were derived using a dietary

- based chronic toxicity value. Dietary

- b ased RQs were calculated using EECs expressed in terms of residue concentration for the various forage categories, and the toxicity value (NOAEC) is expressed in units of dietary concentration
( Table 11 ). RQs exceeded the LOC of 1.0 for all dietary catego ries except for fruits/pods/seed and indicated the potential for adverse effects from chronic exposure to short grass, tall grass, broadleaf plants and arthropods.

Table 11 . Dietary

- based chronic RQs for birds exposed to fluopyram
based on upper

- bound residues on short grass, tall grass, broadleaf plants/small insects, and fruits/pods/seeds/large insects as calculated by

T

- REX



### Dietary item Avian Chronic Risk Quotients a

Short Grass 2.4

Tall Grass 1.1

### 21

Bolded values denote RQ values that exceed the LOC of 1.0



### Mammals Dietary

- based RQs were calculated using EECs expressed in terms of residue concentration for the various forage categories, and the toxicity value (NOAEC) is expressed in units of dietary

concentration. Dose

- based RQs were calculated using EECs expressed in terms of a dose concentration for the various forage categori es and the estimated toxicity value (NOAEL). The

dose

- based EECs are calculated by using the estimated dietary concentrations and assuming the laboratory rat consumes 5% of its body weight daily. Three weight categories (or sizes) were

considered for dose

- based risk calculations ( Tables 12 and 13 )

. Chronic RQs for mammals exceeded the LOC of 1.0 for dose based exposure but not dietary based exposure. Chronic risk was found from dosed based exposure to short grass, tall grass, broadleaf plants and arthropod s for both small and medium sized birds. Exposure to short grass had the potential to adversely affect large birds.

Table 12 . Dose

- based chronic RQs for small (15g), intermediate (35g), and large (1,000g) mammals exposed to fluopyram based on upper

- bound residues on short grass, tall grass, broadleaf plants/small insects, fruits/pods/large insects

and seeds as calculated by T

- R EX

Mammalian Chronic Risk Quotient *

Short

Grass Tall

Grass Broadleaf

Plants Fruits/Pods Arthropods Seeds Body Weight

(g)

15 3.82 1.75 2.15 0.24 1.49 0.05

35 3.26 1.49 1.83 0.20 1.28 0.05

1000 1.75 0.80 0.98 0.11 0.68 0.02 Broadleaf plants 1.4

Fruits/pods/seeds 0.2

Arthropods 1.0

a These values were calculated using the maximum application rate (0.25 lb a.i./A), the maximum number of applications (2), the minimum application
interval (5 days), and a chronic NOAEC = 46.70 mg a.i./kg diet in bobwhite

quail and a default chemical foliar half

- life of 35 days.

### 22 * These values were calculated using the maximum application rate (0.2 5 lb a.i./A), the maximum number of applications (2), the minimum application interval (5 days),

a NOAEC = 13 mg a.i./kg body weight/day in rats and an estimated chronic dietary

NOAEC = 2 60 mg ai/kg diet and a default chemical foliar half

- life of 35 days.

Bolded values denote RQ values that exceed the LOC of 1.0

Table 13 . Dietary

- based chronic RQs for mammals exposed to fluopyram based on upper

- bound residues on short grass, tall grass, broadleaf plants/small insects, and fruits/pods/seeds/large insects as calculated by T

- REX

Mammalian Chronic Risk Quotients *

Short

Grass Tall

Grass Broadleaf

Plants Fruits/Pods/Seeds Arthropods

0.44 0.20 0.25 0.03 0.17

* These values were calculated using the maximum application
rate (0.2 5 lb a.i./A), the maximum number of applications (2), the minimum application interval (5 days), and a chronic

NOAEC = 13 mg a.i./kg body weight/day in rats and an

estimated chronic dietary NOAEC = 260 mg ai/kg diet and a

default chemical foliar half

- life of 35 days.

.



### a) Seed treatments on soybeans and cotton and peanuts

Risks to both avian and mammalian taxa from seed trea t ments for peanuts, soybeans and cotton are presented in Table 14

. The risks from soybeans and cotton were assessed previously (DP
Barcode 414232).

For peanuts , the seed treatment resulted in an acute risk to listed small and medium sized avian

spe cies as well as chronic risk to both listed and non

- listed species of birds and mammals in all weight classes. An RQ of 0. 26 in the avian 20 g category and of 0.12 in the 100 g category

exceeded the acute listed species LOC of 0.1 indicating liste d specie s in these weight class may be adversely affected by acute exposures. Avian chronic RQs were 32 and exceeded the LOC of 1.0 for chronic exposure. Mammalian chronic RQs ranged from 5 to 11, all exceeding the chronic LOC of 1.0, indicating potential chroni c adverse effects when expo sed to fluopyram through peanut seed treatments. There was not any mammalian acute risk identified for any mammalian weight class exposed to peanut seed treatments.

For soybeans, the seed treatment resulted in an acute risk to listed avian species as well as

### 23

chronic risk to both listed and non

- listed species of birds and mammals in all weight classes . An RQ of 0.14 in the avian 20 g category exceeded the acute listed species LOC of 0.1 indicating listed species in this weight class may be adversely affected by acute exposures. Avian chronic RQs were 17.65 and exceeded the LOC of 1.0 for chronic exposure. Mammalian chronic RQs ranged from 2.8 to 6.11, all exceeding the chronic LOC of 1.0, indicating potential chronic

adverse e ffects when exposed to fluopyram through soybean seed treatments. There was not any mammalian acute risk identified for any mammalian weight class exposed to soybean seed

treatments.

For the cotton seed treatment there was potential risk to avian taxa id entified on both an acute and chronic basis. The avian weight class of 20g had an RQ of 0.61 and exceeded the n onlisted species LOC of 0.5 suggesting potential adverse effects to both listed and non

- listed avian species in this weight class. The avian we ight class of 100 g had a RQ of 0. 27 which exceeded

the LOCs for listed species (LOC= 0.1). This suggests that listed species may potentially be adversely a ffected and risks may be mitigated through restricted use patterns. Chronic risk was

identified in all avian weight classes with an RQ of 74.11 in each category greatly exceeding the

chronic LOC of 1.0. The mammalian weight classes of 15g and 35g had RQs of 0.17 and 0.14 respectively for cotton . These both exceed the LOC for listed species (0.1) and indicate potential adverse effects to listed species on an acute exposure basis when exposed to cotton seed treatments. Chronic mammalian RQs ranged from 11.75 to 25.66 and all significantly exceeded the chronic LOC of 1.0 indicating risk to both listed a nd non

- listed species.

Table 14

. Risk quotients for terrestrial animals as a result of seed treatments on peanuts, soybean

and cotton.

Risk Quotients†

Peanuts

Acute (# 1) Acute (# 2) Chronic

Avian (20 g) 0.26 0.01 32.04

Avian (100 g) 0.12 0.00 32.04

Avian (1000 g) 0.04 0.00 32.04

Mammalian (15 g) 0.07 0.00 11.09

Mammalian (35 g) 0.06 0.00 9.48

Mammalian (1000 g) 0.03 0.00 5.08

Soybean

Acute (# 1) Acute (# 2) Chronic

Avian (20 g) 0.14 0.01 17.65

Avian (100 g) 0.06 0 17.65

Avian (1000 g) 0.02 0 17.65

Mammalian (15 g) 0.04 0 6.11

Mammalian (35 g) 0.03 0 5.22

Mammalian (1000 g) 0.02 0 2.8

### 24 Cotton

Acute (# 1) Acute (# 2) Chronic

Avian (20 g) 0.61 0.02 74.11

Avian (100 g) 0.27 0 74.11

Avian (1000 g) 0.09 0 74.11

Mammalian (15 g) 0.17 0.01 25.66

Mammalian (35 g) 0.14 0.01 21.92

Mammalian (1000 g) 0.08 0 11.75

Acute RQ #1 = (mg ai /kg

- bw/day) / LD50

Acute RQ #2 = mg ai ft

- 2 /(LD50*bw)

Avian Chronic RQ =mg kg

- 1 seed / NOAEL
Mammalian Chronic RQ = mg a.i./kg

- bw/day / adjusted

NOAEL

Bolded values denote RQ values that exceed the acute listed species LOC of 0.1 and the chronic LOC of 1.0



### D. Risk Estimation for Terrestrial Plants

As reviewed in the previous assessment, in the vegetative vigor study, sugarbeet had the highest level of inhibition in dry weight, a 20.2% reduction in comparison to the negative control at a fluopyram application rate of 0.222 lb s a.i./A. The rate applied in the Tier I seedling emergence test, 0.444 lbs a.i./A, was greater than the maximum applicati on rate of 0.25 lbs a.i./A. The original buckwheat study submitted for the previous risk assessment showed a 50.4% reduction in dry

we ight at 0.444 lbs a.i./A in the seedling emergence test (MRID 47372349 ; US EPA 2011 ). A

more recent Tier II study submitted for this assess ment (MRID 48934301) demonstrated that there were not any observable effects at the maximum application rates of 0.4 4 lb a.i./A. The NOAEC for this study was 0.4440 lb a.i./A.

A preliminary run of TERR

- PLANT was conducted using the maximum application sc enarios for ground application listed in Table 2

. All EECs ranged f rom 0.002 5 (spra y drift) to 0.0525
(semi

- aquatic areas) lbs a.i./A for ground application s. In all scenarios used in this assessment, there was not any risk identified to either listed or non

- listed monocots and dicots in dry and

semi

- aquatic areas as a result of runoff or spray d rift (RQs ranged from <0.1 to 0.12)

. Similarly,

the in

- furrow treatments also did not exceed the LOC of 1.0. Use of Fluopyram is unlikely to adversely affect terrestrial plants when used according to labels.



# VI. Risk Summary

The RQs are summarized in the a bove tables. Risk associated with the proposed new uses of fluopyram are confined primarily to terrestrial taxa. For spray applications there was chronic dietary based risk from consumption of all dietary categories but the fruit/pods/seeds category. Spray applications also resulted in chronic dosed

- based risk to mammalian taxa in every size

class for short grass for most dietary items for small and medium sized mammals. Exposure to

### 25

Fluopyram via seed treatments potentially poses a cute risk to small and medium sized endangered avian and mammalian species

. There was chronic risk indicated for both avian and

mammali an tax a from all seed treatments.

Citations :

US. EPA 2011. Environmental Fate and Ecological Risk Assessment for Fluopyram Registration (PC Code 080302; DP Barcodes 353315, 369756, and 385637) 

## Appendix I: Labeled uses for fluopyram and mixtures

(1) Abbreviations

A Application using aerial equipment

AirBlast Application using air blast equipment

C Chemigation through the irrigation systems

CG Crop Group

CR Crop

D Drench application to soil

- d Application intervals in days (e.g., 7

- d)

F Application directed to foliage

FDC Fungicide Disease Control

FDS Fungicide Disease Suppression

G Application using ground equipment

MSA Maximum Single Rate (lb a.i/A)

MYA Maximum Yearly Rate (lb a.i/A)

NPC Nematode Pest Control

PHI Pre

- harvest interval (days)

S Application directed to soil

(2) Products: Products are numbered from 1 to 11 in the Tables, below and hereunder the names and active ingredient(s) for these products

Products Names and active(s)

Product

No. Product Name and Active Ingredient(s)

1 FLUOPYRAM 500 SC: a.i: Fluopyram

2 LUNA® PRIVILEGE: a.i: Fluopyram

3 PROPULSE TM : a.i: Fluopyram & Prothioconazole

4 LUNA ® TRANQUILITY: Fluopyram & Pyrimethanil

5 LUNA ® EXPERIENCE: Fluopyram & Tebuconazole

6 LUNA® SENSATION: Fluopyram & Trifloxystrobin

7 FLU+TFS SC 25: a.i: Fluopyram + Trifloxystrobin

### 26

8 FLU+TFS SC 32.5: a.i: Fluopyram + Trifloxystrobin

9 FLU+TFS SC 500: a.i: Fluopyram + Trifloxystrobin

10 13ESP715 3.3 SC: a.i: Fluopyram (master label: Fungicide + Nematicide)

11 13ESP715 3.3 SC: a.i: Fluopyram (Nematicide only)



### Table I

- 1 Artichoke, Beans and Peas, Brassica and Bulb vegetables (refer to Abbreviations , above)

CR or CG Crops Product Purpose

Artichoke Artichoke (globe) MSA= Maximum Single Application MSA= 0.223; Maximum Yearly

Application (MYA)= 0.446 ; 7

- d; Soil or Foliar (S or F); G/A/C/D (ground/aerial/chemigation/Drip): MSA= 0.223 ; MYA= 0.446; 7

- d; S or F; G/A/C/D;

PHI=0 2 FDC

Artichoke (globe): MSA= 0.125; MYA= 0.251; 7

- d; S or F; G/A/C; PHI=0 6 FDC

+FDS

Beans and Peas (dried) Bean ( Lupinus spp., includes grain lupin, sweet lupin, white lupin, and white sweet lupin),

Bean ( Phaseolus spp., includes field bean, kidney bean, lima bean, navy bean, pinto bean, tepary bean), Bean ( Vigna spp., includes adzuki bean, blackeyed pea, catjang, Crowder pea, moth bean, mung bean, rice bean, southern pea, urd bean, Broad Bean (dry), Chickpea, Guar,
Lablab Bean, Pea ( Pisum spp Pea including Field pea and Pigeon pea), Lentil
MSA= 0.178; MYA= 0.446; 7

- d; S or F; G/A/C; PH I=14 3 FDC
Beans only: fresh & dry, except succulent shelled: MSA= 0.167; MYA= 0.334; 10

- d; S or
F; G/A/C; PHI=14 5 FDC

Brassica (Cole) Leafy Vegetables Broccoli, Broccoli raab (rapini), Brussels sprouts, Cabbage, Cauliflower, Cavalo broccolo,

Chinese broccoli (gai lon), Chinese cabbage (bok choy), Chinese cabbage (napa), Chinese mustard cabbage (gai choy), Collards, Kale, Kohlrabi, Mizuna, Mustard greens, Mustard spinach, Rape greens, Turnip greens. Including all cultivars and/or hybrids of these: FDC:
MSA= 0.223; MYA= 0.446; 5

- d; S or F; G/A/C/D; PHI= 0 and NPC: MSA= 0.223; MYA= 0.446; 5

- d; For application refer to Note 1 2 FDC +

NPC
Crop Subgroup 5B: Broccoli raab (rapini), Chinese cabbage (bok choy), Collards, Kale, Mizuma, Mustard greens, Mustard spinach, Rape greens, Turnip greens and/or hybrids of

these: MSA= 0.112; MYA= 0.444; 7

- d; S or F; G/A/C/D; PHI= 7 5 FDC +

FDS

BRASSICA LEAFY VEGETABLES, (HEAD AND STEM SUBGROUP) Broccoli, Chinese broccoli (gai lon), Brussels sprouts, Cabbage, Chinese cabbage (napa), Chinese cabbage (bok choy), Chinese mustard cabbage (gai choy), Cauliflower, Cavalo broccolo, Kohlrabi; Including all cultivars and/or hybrids of these: MSA= 0.125; MYA=
0.251; 7

- d; S or F; G/A/C/D; PHI= 0 6 FDC +

FDS

BRASSICA LEAFY VEGETABLES, (LEAFY GREENS SUBGROUP 5B): Same crops listed for product 5: MSA= 0.125; MYA= 0.251; 7

- d; S or F; G/A/C; PHI= 0 6 FDC +

FDS

Bulb Vegetables Chive fresh leaves, Chive fresh leaves (Chinese), Daylily bulb, Elegans hosta, Fritillaria (bulb

and leaves), Garlic bulb, Garlic bulb (Great headed and Serpent ), Kurrat, Leek, Leek (Lady’s and Wild), Lily bulb, Onion (Beltsville bunching, Bulb, Chinese b ulb, Fresh, Green, Macrostem, Pearl, Potato bulb, Tree tops, and Welsh), Shallot (bulb and fresh leaves). Including all cultivars and/or hybrids of these: MSA= 0.223; MYA= 0.446; 5

- d; S or F;
G/A/C; PHI=0 2 FDC +

FDS

Dry bulb onion, Eschalots, Green onion, Garlic, Leeks, Japanese bunching onion, Scallions, Shallot, Spring onion 0.220

- 0.445/ 7

- d G/A/AB/C: MSA= 0.220; MYA= 0.444000; 7

- d; S or F; G/A/C; PHI= 7 (up to 0.446) 4 FDC +

FDS

Same crops as product 1: MSA= 0.167; MYA= 0.434; 10

- d; S or F; G/A/C; PHI= 7 5 FDC +

FDS

### 27

Note 1: Varies by crop: applied chemical is to reach the root zone by irrigating

- in, drench, and chemigation or in

seed

- furrow

### 28

Table I

- 2 Canola, Carrots, Cereal grains and X

- mass trees (refer to Abbreviations , above)

CR or CG Crops Product Purpose

Canola Subgroup Borage; crambe; cuphea; echium; flax seed; gold of pleasure; hare’s ear mustard; lesquerella;

lunaria;meadowfoam; milkweed; mustard seed; oil radish; poppy seed; rapeseed; sesame; sweet rocket cultivars, varieties; and/or hybrids of these:
MSA= 0.223 ; M YA= 0.446; 12

- d; S or F; G/A/C; PHI= 14 d 2 FDC
Canola, Rapeseed, Indian rapeseed, Field mustard and Crambe: MSA= 0.178; MYA= 0.356;

14

- d; S or F; G/A/C; PHI= 36 (up to 0.446 w/other) 3 FDC

Carrot Tops or greens may be utilized for food or feed. Beet (garden), Burdock (edible), Celeriac,

Chervil (Turnip

- rooted), Chicory, Horseradish, Parsley (Turnip

- rooted), Parsnip, Radish, Oriental Radish (Daikon), Rutabaga, Salsify, Salsify (Black and Spanish), S kirret, Turnip: MSA= 0.223 ; MYA= 0.446; 5

- d; Assume Foliar; G/A/C; PHI= 7 d 2 FDC

Carrot: MSA= 0.125 ; MYA= 0.377; 14

- d; Assume Foliar; G/A/C; PHI= 7 d 6 FDC +

FDS

Cereal Grains,
Except

Rice Crops: Barley, Buckwheat, Corn (sweet corn, field corn, field corn grown for seed, and

popcorn), Millet (pearl and proso), Oats, Popcorn, Rye, Sorghum, Sudan grass, Teosinte,
Triticale, Wheat Plus: Forage, Fodder or Straw from al cereal grain crops stated above:
MSA= 0.223; MYA= 0.446; 14

- d; S or F; G/A/C; PHI= 14 d 2 FDC
Barley, Wheat (spring, durum, and winter) and Triticale (0.178

- 0.294/ 14

- d) G/A/C
MSA= 0.178; MYA= 0.296; 14

- d; S or F; G/A/C; PHI= 30 d (with other=0.446) 3 FDC
Buckwheat, Millet (pearl and proso), Oats and Rye (0.178 0ne application) G MSA= 0.178 One application; S or F; G/A/C; PHI= 30 d (with other=0.446) 3 FDC

Corn (Assume All): MSA= 0.178; MYA= 0.446; 7

- d; S or F; G/A/C; PHI= 14 d for sweet

corn 3 FDC
Wheat and Barley: MSA= 0.122; one application; S or F; G/A/C; PHI= 30 d 5 FDC
Corn: sweet corn, field corn, field corn grown for seed, and popcorn: MSA= 0.167; MYA=
0.334; 14

- d; S or F; G/A/C; PHI= sweet corn= Min 7 fodder, field corn, field corn grown
for seed, and popcorn Min 14 days 5 FDC

Wheat: MSA= 0.112; MYA= 0.220; 14

- d; S or F; G/A/C; PHI= 35 d (with other=0.446) 6 FDC

Christmas

Trees Christmas Trees: MSA= 0.221; MYA= 0.446; 7

- d; F; AirBlast 2 FDP

Christmas Trees: MSA= 0.220; MYA= Not specified but assumed to be 0.446; 7

- d; F;

AirBlast 7 FDC

Christmas Trees: MSA= 0.220; MYA= Not specified but assumed to be 0.446; 7

- d; F;

AirBlast 9 FDC

Christmas Trees: MSA= 0.224; MYA= 0.446; 7

- d; F; AirBlast 10 FDC

### 29

Table I

- 3 Citrus, Cotton and Cucurbits (refer to Abbreviations , above)

CR or CG Crops Product Purpose

Citrus Australian desert lime, Australian finger

- lime, Australian round lime, Brown River finger lime,

Calamondin, Citron, Citrus hybrids, Grapefruit, Japanese summer grapefruit, Kumquat, Lemon, Lime, Mediterranean mandarin, Mount white lime, New Guinea wild lime, Orange (Sour and Sweet), Pummelo, Russell River lime, Satsuma mandarin, Sweet lime, Tachibana orange, Tahiti lime, Tangelo, Tangerine (Mandarin), Tango r, Trifoliate orange, Uniq fruit, White sapote,
( Casimiroa spp.) and cultivars, varieties, and/or hybrids of these: FDC: MSA= 0.223; MYA=
0.446; 7

- d; S or F; G/A/C; PHI= 7 d and NPC: MSA= 0.223; MYA= 0.446; 30

- d; For application refer to Note 1; PHI= 7 d 2 FDC +

NPC

Non

- bearing citrus trees: MSA= 0.221; MYA= 0.446; 7

- d; F; AirBlast Drip 1 FDC

Non

- bearing trees: MSA= 0.221; MYA= 0.446; 30

- d; For application refer to Note 1 1 NPC

Lemons: MSA= 0.220 one application; S or F; G/A/C; PHI= 7 d (up to 0.446) 4 FDS
Calamondin, Citrus citron, Citrus hybrids ( Citrus spp., includes chironja, tangelo and tangor), Grapefruit, Kumquat, Lemon, Lime, Mandarin (tangerine), Orange (sweet and sour), Pummelo, Tangelo, Satsuma mandarin, White sapote ( Casimiroa spp.), and other cultivars and/or hybrids

of these: MSA= 0.125; MYA= 0.446 (0.448?); 7

- d; S or F; G/A/C; PHI= 7 d (up to 0.446) 6 FDC

Non

- bearing citrus trees: MSA= 0.125; MYA= 0.445; 7

- d; F; AirBlast 7 FDC

Non

- bearing citrus trees: MSA= 0.125; MYA= 0.445; 7

- d; F; AirBlast 9 FDC

Non

- bearing citrus trees: MSA= 0.224; MYA= 0.446; 7

- d; F; AirBlast 10 FDC

Cotton and

Cotton Seed Subgroup
(20c) Includes cultivars, varieties and other hybrids of these: FDC: MSA= 0.223 (one appl. Foliar);

S or F; G/A/C/; PHI= 30 d and NPC: MSA= 0.223 (one appl. Foliar); For application refer
to note 1; PHI= 30 d 2 FDC +

NPC

Cotton: FDC: MSA= 0.222; MYA= 0.444; 7

- d; S or F; G/A/C; PHI= 30 d 5 FDC

Cucurbit Vegetables Chayote (fruit), Chinese waxgourd (Chinese preserving melon), Citron melon, Cucumber,

Gherkin, Gourd (edible, includes hyotan, cucuzza, hechima, Chinese okra), Momordica spp. (includes balsam apple, balsam pear, bitter melon, Chinese cucumber), Muskmelon ( hybrids

and/or cultivars of Cucumis melo including true cantaloupe, cantaloupe, casaba, Crenshaw melon, golden pershaw melon, honeydew melon, honey balls, mango melon, Persian melon, pineapple melon, Santa Claus melon, snake melon), Pumpkin, Squash (includ es summer squash types such as: crookneck squash, scallop squash, straightneck squash, vegetable marrow, zucchini, and winter squash types such as acorn squash, butternut squash, calabaza, Hubbard squash, spaghetti squash), Watermelon (includes hybrids and /or varieties of Citrullus lanatus ): FDC: MSA= 0.223; MYA= 0.446; 5

- d; S or F; G/A/C/D; PHI= 0 d And NPC: MSA= 0.223; MYA= 0.446; 5

- d; For application refer to Note 1; PHI= 0 d 2 FDC +

NPC

Chayote (fruit); Chinese waxgourd (Chinese preserving melon); citron melon; cucumber; gherkin; edible gourd (includes hyotan, cucuzza, hechima, Chinese okra); Momordica spp (includes balsam apple, balsam pear, bitter melon, Chinese cucumber); muskmelon (includes cantaloupe); pumpkin; squash (summer and
winter, includ es butternut squash, calabaza, hubbard squash, acorn squash, spaghetti squash);

watermelon: FDC: MSA= 0.178; MYA= 0.446 (one soil Appl. + two foliar); 5

- d; S or F;
G/A/C/ D; PHI= 7 d 3 FDC

All crops listed for product 3 above (CG 9): FDC: MSA= 0.222; MYA= 0.444; 10

- d; S or F;
G/A/C; PHI= 7 d 5 FDC

All crops listed for product 3 above MSA= 0.125; MYA= 0.446 (0.448?); 7

- d; S or F; G/A/C; PHI= 0 d (up to 0.446) 6 FDC

+ FDS

Note 1: Varies by crop: applied chemical is to reach the root zone by irrigating

- in, drench, and chemigation or in

seed

- furrow

### 30

Table I

- 4 Fruiting vegetables, Ginseng Grapes and small vine fruits (refer to Abbreviations , above)

CR or GC Crops Product Purpose

Fruiting
Vegetables African eggplant, Bush tomato, Cocona, Currant tomato, Eggplant, Garden huckleberry, Goji

berry, Groundcherry, Martynia, Naranjilla, Okra, Pea eggplant, Pepino, Pepper ( Capsicum spp., including Bell, Chili, Cooking, Pimento and Sweet), Roselle, Scarlet eggplant, Sunberry, Tomatillo, Tomato, Tree tomato, and cultivars, varieties, and/or hybrids of these
FDC: MSA= 0.233; MYA= 0.446; 5

- d; S or F; G/A/C/D; PHI= 0 d NPC: MSA= 0.233; MYA= 0.446; 5

- d; For application refer to Note 1; PHI= 0 d 2 FDC

+
NPC

Tomato MSA= 0.091; MYA= 0.444; 7

- d; S or F; G/A/C; PHI= 1 d 4 FDC

Okra
MSA= 0.167; MYA= 0.444; 14

- d; S or F; G/A/C; PHI= 3 d 5 FDC

All crops listed for product 1 above (CG 8) MSA= 0.222; MYA= 0.444; 7

- d; S or F; G/A/C; PHI= 7 d 5 FDC
Eggplant, Groundcherry, Okra, Pepinos, Pepper ( Capsicum spp., including bell, chili, cooking, pimento and sweet), Tomatillo, Tomato. MSA= 0.125; MYA= 0.446 (0.448?); 7

- d; S or F; G/A/C; PHI= 3 d (up to 0.446) 6 FDC

+ FDS

Ginseng Ginseng

MSA= 0.223; MYA= 0.446; 5

- d; S or F; G/A/C; PHI= 7 d 2 FDC
Ginseng MSA= 0.220; MYA= 0444; 7

- d; S or F; G/A/C; PHI= 30 d 4 FDC
Ginseng MSA= 0.125; MYA= 0.251; 7

- d; S or F; G/A/C; PHI= 7 6 FDC

Grapes and

small vine fruits (except fuzzy
kiwifruit) 

### Amur river grape, Gooseberry, Grape, Kiwifruit, Hardy, Maypop, Schisandra berry, and

cultivars, varieties, and/or hybrids of these
FDC: MSA= 0.223; MYA= 0.446; 12

- d; S or F; G/A/C/D; PHI= 7 d NPC: MSA= 0.223; MYA= 0.446; 12

- d; For application refer to note 1; PHI= 7 d 2 FDC

+ FDS

+
NPC

Non

- bearing grapes:
MSA= 0.221; MYA= 0.446; 12

- d; F; AirBlast Drip 1 FDC

Same crops listed for product 1 MSA= 0.220; MYA= 0.444; 12

- d; S or F; G/A/C; PHI= 7 d 4 FDC

Same crops listed for product 1
MSA= 0.112; MYA= 0.444; 12

- d; S or F; G/A/C; PHI= 14 d 5 FDC

+ FDS

Same crops listed for product 1 except (concord grapes) MSA= 0.125; MYA= 0.446 (0.448?); 7

- d; S or F; G/A/C; PHI= 14 d (up to 0.446) up to 6 applications lowest single application= 0.066 6 FDC

+ FDS

Non

- bearing grapes: MSA= 0.125; MYA= Maximum 6 applications Assumed= 0.446 as it is not specified (minimum= 0.049); 12

- d; F; AirBlast 7 FDC

Non

- bearing grapes: MSA= 0.125; MYA= 6 applications Assumed= 0.446 as it is not specified (minimum= 0.049); 12

- d; F; AirBlast 9 FDC

Non

- bearing grapes: MSA= 0.224; MYA= 0.446; 12

- d; F; AirBlast 10 FDC

Note 1: Varies by crop: applied chemical is to reach the root zone by irrigating

- in, drench, and chemigation or in

seed

- furrow

### 31

Table I

- 5 Grasses, Herbs, and Hops, Leafy green/petiole ve getables (refer to Abbreviations , above)

CR or GC Crops Product Purpose

Grasses for forage/feed (including

grasses grown for seed) Grass forage, fodder, or hay: Any grass ( Gramineae family) except sugarcane that will be fed

to or grazed by livestock, all pasture and range grasses and grasses grown for hay or silage MSA= 0.223; MYA= 0.446; 14

- d; S or F; G/A/C; PHI= 7 d 2 FDC

Same crops listed for product 1
MSA= 0.222; MYA= 0.444; 14

- d; S or F; G/A/C; PHI= 7 d 5 FDC

Same crops listed for product 1

MSA= 0.125; MYA= 0.251; 14

- d; S or F; G/A/C; PHI= 7 6 FDC

Herbs and Spices (except black pepper) Allspice, Angelica, Anise (anise seed), Anise (star), Annatto (seed), Balm (lemon balm),

Basil (fresh and dried), Borage, Bumet, Camomile, Caper buds, Caraway, Caraway (black), Cardamom, Cassia (bark and buds), Catnip, Celery seed, Chervil (dried), Chinese chive, Chive, Cinnamon, Clary, Clove (buds), Coriander (cilantro or Chinese parsley leaves, Coriander seed (cilantro seed), Costmary,
Culantro (leaf and seed), Cumin, Curry leaf, Dill (seed), Dillweed, Fennel [common and Florence (seed)], Fenugreek, Grains of paradise, Horehound, Hyssop, Juniper berry, Lavender, Lemongrass, Lovage (leaf and seed), Mace, Marigold, Marjoram, Mustard (seed), Nasturtium, Nutmeg, Par sley (dried), Pennyroyal, Poppy (seed), Rosemary, Rue, Saffron, Sage, Savory (summer and winter), Sweet bay (bay leaf), Tansy, Tarragon, Thyme, Vanilla, Wintergreen, Woodruff, Wormwood. MSA= 0.223; MYA= 0.446; 7

- d; S or F; G/A/C/D; PHI= 0 d 2 FDC

+ FDS
Same crops listed for product 1 MSA= 0.125; MYA= 0.251; 14

- d; S or F; G/A/C; PHI= 7 6 FDC

Hops Hops: MSA= 0.223; MYA= 0.446; 14

- d; S or F; G/A/C/D; PHI= 7 d 2 FDC

Hops: MSA= 0.222; MYA= 0.444; 14

- d; S or F; G/A/C; PHI= 14 d 5 FDC

+
FDS

Hops

MSA= 0.125; MYA= 0.446 (0.448?); 14

- d; S or F; G; PHI= 14 d (up to 0.446) up to 4 applications Min 0.049 6 FDC

+ FDS

Leafy Green Vegetables** Amaranth (Leafy amaranth, Chinese spinach, Tampala), Arugula (Roquette), Cardoon,

Celery, Celtuce, Chervil, Chinese celery, Chrysanthemum (Edible

- leaved and Garland), Cilantro, Corn salad, Cress (Garden), Cress (Upland, Yellow rocket, Winter cress),
Dandelion, Dock (Sorrel), Endive (Escarole), Florence fennel (Sweet anise, Sweet fennel,
Finocchio), Lettuce (Head and Lea f), Orach, Parsley, Purslane (Garden and Winter), Radicchio (Red chicory), Rhubarb, Spinach [including New Zealand and vine (Malabar spinach, Indian spinach)], Swiss chard, Watercress
MSA= 0.223; MYA= 0.446; 7

- d; S or F; G/A/C/D; PHI= 0 d 2 FDC

Same crops listed for product 1
MSA= 0.125; MYA= 0.251; 14

- d; S or F; G/A/C; PHI= 7 6 FDC

+
FDS

Leafy Petiole Vegetables Cardoon, Celery, Celtuce, Chinese celery, Florence fennel (including, sweet anise, sweet

fennel, Finocchio), Rhubarb, Swiss chard

MSA= 0.095; MYA= 0.251; 14

- d; S or F; G/A/C/D; PHI= 7 d 6 FDC

+ FDS

### 32

Table I

- 6 Legumes and Ornamentals (refer to Abbreviations , above)

CR or GC Crops Product Purpose

Legume Vegetables (including soybean) Crops: Edible Podded and Succulent Shelled Pea and Bean and Dried Shelled Pea and Bean,

Bean ( Lupinus spp., includes Grain lupin, Sweet lupin, White lupin, and White sweet lupin),
Bean ( Phaseolus spp., includes Field bean, Kidney bean, Lima bean, Navy bean, Pinto bean, Runner bean, Snap bean, Tepary bean, Wax bean), Bean ( Vigna spp., includes Adzuki bean, Asparagus bean, Blackeyed pea, Catjang, Chinese longbean, Cowpea, Crowder pea, Moth bean, Mung bean, Rice bean, Southern pea, Urd bean, Yardlong bean), Pea ( Pisum spp., includes Dwarf pea, Edible pea, Edib le

- pod pea, English pea, Field pea, Garden pea, Green pea, Snow pea, Sugar snap pea), Other Beans and Peas [Broad bean (Fava), Chickpea (Garbanzo bean), Guar, Jackbean, Lablab bean (Hyacinth bean), Lentil, Pigeon pea, Soybean, Soybean (immature seed), Swor d bean

Plus: plant parts of any legume that will be used as animal feed FDC: MSA= 0.2230; MYA= 0.446; 7

- d; S or F; G/A/C; PHI= 0 d NPC: MSA= 0.223; one application; For application refer to Note 1; PHI= 0 d 2 FDC

+
NPC
Soybean crop only
MSA= 0.134; MYA= 0.403; 10

- d; S or F; G/A/C; PHI= 21 d 3 FDC
Soybean crop only
MSA= 0.112; MYA= 0.337; 10

- d; S or F; G/A/C; PHI= 21 d 5 FDC

+ FDS
Soybean crop only
MSA= 0.125; MYA= 0.251; 10

- d; S or F; G/A/C; PHI= 21 d 6 FDC

+ FDS

Ornamentals Ornamentals (foliar or flower Diseases) in residential and commercial landscapes,

interiorscapes, field grown and container ornamentals in nurseries and greenhouses, lath houses, shade houses, containers and other enclosed structures. Restricted for application to

non

- bearing fr uit trees G (foliar)

1 FDC Ornamentals (for all listed ornamentals) MSA= 0.221; MYA= 0.446; 5

- d; F or Drench; G/C

Ornamental sunflower: MSA= 0.221; MYA= 0.446; 14

- d; F; G/C

Spot Treatment: Same as Turf (will be low rate compared to total treatment)

Ornamentals (foliar or stem, root and Damping off of New Seedlings Diseases) in ornamentals listed above for product 2
MSA= 0.130; MYA= 0.445 for plants grown in outdoor nurseries, outdoor seedbeds, field
plantings, and landscapes and 0.130 for foliar application ; 7

- d; F or Drench; G 7 FDC

Ornamentals (foliar or stem, root and Damping off of New Seedlings Diseases) in ornamentals listed above for product 2 MSA= 0.131; MYA= 0.445 for plants grown in outdoor nurseries, outdoor seedbeds, field
plantings, and landscapes and 0.131 for foliar application ; 7

- d; F or Drench; G 9 FDC

Ornamental sunflower: MSA= 0.224; MYA= 0.446; 7

- d; F; G 10 FDC

Ornamentals: MSA= 0.223 (30

- d) Or one application 0.446; Apply by soil Drench 10 NPC

Spot Treatment Same as Turf (will be low rate compared to total treatment) 10 FDC

+
NPC

Ornamentals: MSA= 0.223 (30

- d) Or one application 0.446; Apply by soil Drench 11 NPC

Spot Treatment Same as Turf (will be low rate compared to total treatment) 11 NPC

Note 1: Varies by crop: applied chemical is to reach the root zone by irrigating

- in, drench, and chemigation or in

seed

- furrow

### 33

Table I

- 7 Peanuts, Pome Fruits, and Potato and Other Tuberous, and Corm Vegetables (refer to

Abbreviations , above)

CR or GC Crops Product Purpose

Peanuts Peanuts crop

FDC: MSA= 0.223; MYA= 0.446; 14

- d; S or F; G/A/C; PHI= 7 d NPC: MSA= 0.223; one application; For application refer to Note 1 2 FDC +

NPC

Peanuts Seed Treatment One application at 0.284 lb a.i/A 2 FDC +

NPC

Peanut crop MSA= 0.178; MYA= 0.446; 14

- d; S or F; G/A/C; PHI= 14 d (up to 0.446 w/other) 3 FDC

Peanut crop MSA= 0.205; MYA= 0.444; 14

- d; S or F; G/A/C; PHI= 14 d 5 FDC +

FDS

Peanut crop MSA= 0.115; MYA= 0.446 (0.448); 14

- d; S or F; G/A/C; PHI= 14 d 6 FDC +

FDS

Pome Fruits Apple, Azarole, Crabapple, Loquat, Mayhaw, Medlar, Pear, Pear (Asian), Quince, Quince

(Chinese and Japanese), Tejocote, and cultivars, varieties, and/or hybrids of these
MSA= 0223; MYA= 0.446; 7

- d; S or F; G/A/C/D; PHI= 7 d 2 FDC +

FDS

None bearing: MSA= 0.221; MYA= 0.446; 7

- d; F; AirBlast Drip 1 FDC
CG 11: Apple, Crabapple, Loquat, Mayhaw, Pear, Oriental pear, Quince
MSA= 0.130; MYA= 0.444; 7

- d; S or F; G/AB/C; PHI= 72 d 4 FDC
CG 11: Apple, Crabapple, Loquat, Mayhaw, Pear, Oriental pear, Quince
MSA= 0.131; MYA= 0.444; 10

- d; S or F; G/AB/C; PHI= 75 d 5 FDC +

FDS
Crops listed for product 4: MSA= 0.095; MYA= 0.345; 7

- d; S or F; G/A/C/D; PHI= 14 d; not more than 4 applications Min application= 0.082 6 FDC
None bearing: MSA= 0.095; MYA= 0.345; 7

- d; F; AirBlast 7 FDC
None bearing: MSA= 0.095; MYA= 0.345; 7

- d; F; AirBlast 9 FDC

Non

- bearing trees: MSA= 0.224; MYA= 0.446; 7

- d; F; AirBlast 10 FDC

Potato and

Other
Tuberous,

and Corm
Vegetables Arracacha, Arrowroot, Artichoke (Chinese and Jerusalem), Canna (Edible), Cassava (Bitter

& Sweet), Chayote (root), Chufa, Dasheen, Ginger, Leren, Potato, Sweet potato, Tanier (Cocoyam), Turmeric, Yam bean (Jicama, Manoic pea), Yam (True) FDC: MSA= 0.223; MYA= 0.446; 5

- d; S or F; G/A/C; PHI= 7 d NPC: MSA= 0.223; one application; For application refer to Note 1 2 FDC +

FDS +

NPC

Same crops above MSA= 0.091; MYA= 0.444; 7

- d; S or F; G/A/C; PHI= 7 d 4 FDC

Arracacha, Arrowroot, Artichoke (Chinese and Jerusalem), Beet (garden), Burdock (edible), Canna (edible, Queensland arrowroot), Cassava (bitter & sweet), Celeriac (celery root), Chayote (root), Chervil (turnip

- rooted), Chicory, Chufa, Dasheen (taro), Ginger, Horseradish, Leren, Parsley (turnip

- rooted), Parsnip, Potato, Radish, Oriental radish (daikon), Rutabaga, Salsify (black), Salsify (oyster plant), Salsify (Spanish), Skirret, Sweet potato, Tanier (cocoyam), Turmeric, Turnip, Yam bean (jicama, Manoic pea), Yam (true). ( See separate use directions for Artichoke (globe), Carrot, Ginseng, and Sugarbeet ) MSA= 0.095; MYA= 0.377; 14

- d; S or F; G/A/C; PHI= 7 d; No more than 4 applications noting that the minimum rate= 0.082 6 FDC +

FDS

Note 1: Varies by crop: applied chemical is to reach the root zone by irrigating

- in, drench, and chemigation or in

seed

- furrow

### 34

Table I

- 8 Small berries and Stone fruits (refer to Abbreviations , above)

CR or GC Crops Product Purpose

Small Berries Blackberry Rubus spp., (including Andean Blackberry, Artic blackberry, Bingleberry, Black

satin berry, Boysenberry, Brombeere, California blackberry, Chesterberry, Cherokee blackberry, Cheyenne blackberry, Common blackberry, Coryberry, Darrowberry, Dewberry, Dirksen thornless berry, Evergreen blackberry, Himalayaberry, Hullberry, Lavacaberry, Loganberry, Lowberry, Lucretiaberry, Mammoth blackberry, Marionberry, Mora, Mures deronce, Nectarberry, Northern dewberry, Olallieberry, Oregon evergreen berry , Phenomenalberry, Rangeberry, Ravenberry, Rossberry, Shawnee blackberry, Southern dewberry, Tayberry, Youngberry, Zarzamora, and cultivars, varieries, and/or hybrids of these. Raspberry Rubus spp. ( Rubus occidentalis

, Rubus strigosus

, Rubus idaeus ) (inclu ding Bababerry, Black raspberry, Blackcap, Framboise, Frambueso, Himbeere, Keriberry, Mayberry, Purple raspberry, Red raspberry, Thimbleberry, Tulameen, Wild raspberries, Yellow raspberry) and cultivars, varieties, and/or hybrids of these.
MSA= 0.223; MYA= 0.453; 7

- d; S or F; G/A/C/D; PHI= 0 d 2 FDC

+ FDS
Bushberry (Aronia), Blueberry (Highbush and lowbush), Currant (Buffalo), Guava (Chilean), Currant (Black and Red), Barberry (European), Elderberry, Gooseberry, Cranberry (highbush), Honeysuckle, Huckleberry, Jostaberry, Juneberry, Currant (Native), Salal, Sea

buckt horn and cultivars, varieties, and/or hybrids of these
MSA= 0.178; MYA= 0.356; 7

- d; F; G/C; PHI= 7 d (up to 0.446 w/other) 3 FDC
Blackberry, Raspberry and Bushberry 0.220

- 0.445/ 7

- d G/A/AB/C
MSA= 0.220 ; MYA= 0.444; 7

- d; S or F; G/A/C; PHI= 0 d 4 FDC

Stone Fruits Apricot, Apricot (Japanese), Capulin, Cherry (Black, Nanking, Sweet, Tart), Jujube

(Chinese), Nectarine, Peach, Plum, Plum (American, Beach, Canada, Cherry, Chickasaw, Damson, Japanese, Klamath), Prune, Plumcot, Sloe, and cultivars, varieties, and/or hybrids of

these MSA= 0.223; MYA= 0.445; 5

- d; S or F; G/A/C/D; PHI= 0 d 2 FDC

None bearing drip or sprat early bloom depending on the disease
MSA= 0.221; MYA= 0.446; 5

- d; F; AirBlast Drip 1 FDC

Apricot, Nectarine, Peach, Plum (all varieties including Chickasaw, Damson, Japanese, and Stanley), Plumcot, Prune (fresh and dried) MSA= 0.220; MYA= 0.444; 7

- d; S or F; G/AB/C; PHI= 30 d 4 FDC

+ FDS

Crop Group 12: Apricot, Cherry (sweet and tart), Nectarine, Peach, Plum (all varieties including Chickasaw, Damson, Japanese, and Stanley), Plumcot, Prune (fresh and dried).
MSA= 0.131; MYA= 0.444; 7

- d; S or F; G/AB/C; PHI= 0 d 5 FDC

Apricot, Cherry (sweet and tart), Nectarine, Peach, Plum (including C hickasaw, Damson and Japanese), Plumcot, Prune (fresh and dried). MSA= 0.125; MYA= 0.446 (0.448?); 7

- d; S or F; G/A/C; PHI= 1 d No more than 4 application Min application rate= 0.082 6 FDC

None bearing MSA= 0.125; MYA= 0.251 not more than 4 applications (minimum application 0.082);

7

- d; F; AirBlast 7 FDC

None bearing
MSA= 0.125; MYA= 0.251; 7

- d; F; AirBlast 9 FDC

Non

- bearing trees
MSA= 0.224; MYA= 0.446; 5

- d; F; AirBlast 10 FDC

### 35

Table I

- 9 Strawberry, Sugar beet, and Sunflower (refer to Abbreviations , above)

CR or GC Crops Product Purpose

Strawberry

and Other

Low

- growing

Berries Bearberry, Bilberry, Blueberry (Low

- bush), Cloudberry, Cranberry, Lingonberry, Muntries,

Partridgeberry, Strawberry FDC: MSA= 0.223; MYA= 0.446; 7

- d; 7

- d; S or F; G/A/C/D; PHI= 0 d NPC: MSA= 0.223; MYA= 0.446; 7

- d; For application refer to Note 1; PHI= 0 d 2 FDC

+NPC
All of the above except strawberry
MSA= 0.135; MYA= 0.313; 7

- d; F; G/C; PHI= 45 d (up to 0.446 w/other) 3 FDC
Bearberry, Bilberry, Blueberry (Low

- bush), Cloudberry, Cranberry, Ligonberry, Muntries, Partridgeberry, Strawberry
MSA= 0.220; MYA= 0444; 7

- d; S or F; G/A/C; PHI= 1 d 4 FDC +

FDS
Crops the same as listed for product 4, above MSA= 0.125; MYA= 0.446 (27.3=0.448? should be 27.2=0.446); 7

- d; S or F; G/A/C; PHI= 0 d Min application rate= 0.067 6 FDC +

FDS

Sugar beet Sugar beet

MSA= 0.223; MYA= 0.453; 5

- d; F; G/A/C; PHI= 7 d 2 FDC
Sugar beet MSA= 0.178; MYA= 0.446; 14

- d; S or F; G/A/C; PHI= 7 d 3 FDC
Sugar beet MSA= 0.125; MYA= 0.330; 10

- d; S or F; G/A/C; PHI= 21 d 6 FDC

Sunflower Subgroup Calendula, castor oil plant, Chinese tallowtree, euphorbia, evening primrose, jojoba, niger

seed, rose hip, safflower, stokes aster, sunflower, tallowwood, tea oil plant, vernonia,
cultivars, varieties, and/or hybrids of these
MSA= 0.223; MYA= 0.446; 14

- d; S or F; G/A/C; PHI= 14 d 2 FDC

Sunflower: MSA= 0.167; MYA= 0.444; 14

- d; S or F; G/A/C; PHI= 50 d 5 FDC

Note 1: Varies by crop: applied chemical is to reach the root zone by irrigating

- in, drench, and chemigation or in

seed

- furrow

### 36

Table I

- 10 Tree nuts (refer to Abbreviations , above)

CR or GC Crops Product Purpose

Tree

Nuts African nut

- tree, Almond, Beechnut, Brazil nut, Brazilian pine, Bunya, Bur oak, Butternut, Cajou

nut, Candlenut, Cashew, Chestnut, Chinquapin, Coconut, Coquito nut, Dika nut, Ginkgo, Guiana chestnut, Hazelnut (Filbert), Heartnut, Hickory nut, Japanese horse

- chestnut, Macadamia nut (bush nut), Mongongo nut, Monkey

- pot, Monkey puzzle nut, Okari nut, Pachira nut, Peach palm nut,

Pecan, P equi, Pili nut, Pine nut, Pistachio, Sapucaia nut, Tropical almond, Walnut [including Black

and English (Persian) walnuts], Yellowhorn, and cultivars, varieties, and/or hybrids of these
MSA= 0.223; MYA= 0.446; 7

- d; S or F; G/A/C/D; PHI= 7 d 2 FDC

Almonds MSA= 0.220; MYA= 0.444; 7

- d; S or F; G/A/AB/C; PHI= 30 d 4 FDC

+
FDS

Pistachio MSA= 0.220; MYA= 0.444; 7

- d; S or F; G/A/AB/C; PHI= 30 d 4 FDC

Crop Group 14 ( See separate use directions for: Almonds, Pecan, and Pistachio ): Beech nut,
Brazil nut, Butternut, Cashew, Chestnut, Chinquapin, Filbert (hazelnut), Hickory nut, Macadamia nut (bush nut), Walnut [including black and English (Persian) walnuts] MSA= 0.222; MYA= 0.444; 7

- d; S or F; G/A/AB/C; PHI= 35 d 5 FDC

+
FDS

Pecans MSA= 0.220; MYA= 0.444; 14

- d; S or F; G/A/AB/C; PHI= shucks begin to split 5 FDC

Pistachio MSA= 0.220; MYA= 0.444; 10

- d; S or F; G/A/AB/C; PHI= 35 d 5 FDC

Almonds MSA= 0.220; MYA= 0.444; 7

- d; S or F; G/A/AB/C; PHI= 35 d 5 FDC

+
FDS

Almonds MSA= 0.125; MYA= 0.446 (0.448?); 7

- d; S or F; G/A/AB/C; PHI= 14 d 6 FDC

Pecans MSA= 0.125; MYA= 0.446 (0.448?); 14

- d; S or F; G/A/AB/C; PHI= 30 Maximum 6 applications Min application= 0.067 6 FDC

Pistachio MSA= 0.125; MYA= 0.377; 14

- d; S or F; G/A/AB/C; PHI= 28 d 6 FDC

( See separate use directions for: Almonds, Pecan, and Pistachio ): Beech nut, Brazil nut, Butternut, Cashew, Chestnut, Chinquapin, Filbert (hazelnut), Hickory nut, Macadamia nut (bush nut), Walnut [including black and English (Persian) walnuts]. MSA= 0.125; MYA= 0.446 (0.448?); 7

- d; S or F; G/A/AB/C; PHI= 60 d 6 FDC

Non

- bearing tree nuts MSA= 0.125; MYA= 0.251 not more than 4 applications (minimum application= 0.082; 7

- d; F;

AirBlast 7 FDC

Non

- bearing tree nuts MSA= 0.125; MYA= 0.251 not more than 4 applications (minimum application= 0.082; 7

- d; F;

AirBlast 9 FDC

### 37

### 38

Table I

- 11 Turf (refer to Abbreviations , above)

CR or GC Crops Product Purpose

Turf Areas: Turf on golf courses, sod farms, sport fields, residential, institutional, municipal, commercial,

and other turf grass areas Grass types:

 All cool season turf grasses such as Bent grasses, Bluegrasses, Fescues, Ryegrasses, including
mixtures thereof;

 All warm season grasses such as Bermudagrass, St Augustine grass, Seashore paspalum, Kikuyu grass, and Zoysia grass
FDC: MSA= 0.226; MYA= 0.446; 7

- 14

- d (for low/high rates); F; G/C NPC: MSA= 0.226; MYA= 0.446; 14

- d; Or one application at 0.453; For application refer to note

2

1 FDC +

NPC

Spot treatment: Use maximum rates

FDC: MSA= 5.20 E

- 6 /sq ft (5.20 E

- 2 /Acre) Four Appl./= MYA= 0.208; 14

- d; F; G/C

NPC: MSA= 1.04 E

- 5 /sq ft (Four Appl./= MYA= 0.416; 14

- d; For application refer to Note 2

Turf as specified for product 2, above

FDC: MSA= 0.212

- 0.446; MYA= 0.446; 7

- 14 d (for low/high rates); F; G NPC: MSA= 0.212; MYA= 0.446; 14 d; Or one application at 0.446; For application refer to Note

2 7 FDC

+
NPC

Turf as specified for product 2, above

FDC: MSA= 0.212

- 0.446; MYA= 0.446; 7

- 14 d (for low/high rates); F; G NPC: MSA= 0.212; MYA= 0.446; 14 d; Or one application at 0.446; For application refer to Note

2 8 FDC

+
NPS

Spot treatment: 4 times the highest rate for 10,00 sq. ft instead of 1,000 sq ft 8 FDC

+
NPC

Turf as specified for product 2, above

FDC: MSA= 0.214

- 0.429; MYA= 0.445; 7

- 10

- 14 d (for low/high rates); F; G

NPC: MSA= 0.214

- 0.429; MYA= 0.445; 14

- d; For application refer to Note 2 9 FDC

+
NPC

Turf as specified for product 2, above

FDC: MSA= 0.057

- 0.227; MYA= 0.446; 7

- 14 d (for low/high rates); F; G/Drench

NPC: MSA= 0.227

- 0.455; MYA= 0.446; 14

- d; For application refer to Note 2 10 FDC

+
NPC

Spot treatment: 4 times the highest rate for 10,00 sq. ft instead of 1,000 sq ft 10 FDC

+
NPC

Turf as specified for product 2, above

MSA= 0.227

- 0.455; MYA= 0.446; 14

- d; Appli. For application refer to Note 2 11 NPC

Spot treatment: 4 times the highest rate for 10,00 sq. ft instead of 1,000 sq ft 11 NPC

Note 2: Irrigate

- in to the root zone



# Appendix 2 :

Freshwater

Fish Freshwater

Invertebrates Freshwater

Fish Freshwater

Invertebrates

### 39

Crop Group/Crops Scenario Giving the Highest EECs Peak

EEC (μg/L) Acute

EC/LC50
(μg a.i./L) Acute

EC/LC50 (μg
a.i./L) Acute RQ Acute RQ

Artichoke 

### Artichoke 21.6 >1780 >17000 <0.01 <0.01

Beans & Peeas 

### ILbeansNMC_+65 47.8 >1780 >17000 <0.03 <0.01

Brassica Leafy Vegetables 

### CAColeCropRLF_V2_+65 37.3 >1780 >17000 <0.02 <0.01

Bulb Vegetables 

### GAOnion_WirrigSTD_+210 23.6 >1780 >17000 < 0.01 <0.01

Canola 

### NDcanolaSTD_+95 31.5 >1780 >17000 <0.02 <0.01

Carrot 

### FLcarrotSTD_+0 40.2 >1780 >17000 <0.02 <0.01

Cereals: Corn and Sorghum 

### MScornSTD_+135 &
KSCornStd_+160 50.1 >1780 >17000 <0.03 <0.01

Cereals: Wheat

& others 

### TXwheatOP_+235 51.3 >1780 >17000 <0.03 <0.01

Christmas Trees 

### Christmas Trees 6.94 >1780 >17000 <0.01 <0.01

Citrus 

### FLcitrusSTD_+145 20.6 >1780 >17000 <0.01 <0.01

Cotton 

### STXcottonNMC_+160 &

NCcottonSTD_+75 31.7 >1780 >17000 < 0.02 <0.01

Cucurbits 

### STXmelonNMC_+9 &

FLcucumberSTD_+0 39.2 >1780 >17000 <0.02 <0.01

Fruiting Vegetables 

### STXvegetableNMC_+170 &

FLpeppersSTD_+10 40.7 >1780 >17000 <0.02 <0.01

Ginseng 

### MNsugarbeetSTD_+10 34.1 >1780 >17000 <0.02 <0.01

Grapes & Small

Vine Fruits 

### NYGrapesSTD_+90 19.6 >1780 >17000 <0.01 <0.01

Grasses for Forage/Seeds 

### ORgrassseedSTD_+160 21.4 >1780 >17000 <0.01 <0.01

Herbs & Spices 

### CAColeCropRLF_V2_+60 36.7 >1780 >17000 <0.02 <0.01

Hops 

### ORhopsSTD_+140 24 >1780 >17000 <0.01 <0.01

Leafy Vegetables +

Petiole 

### CAlettuceSTD_+95 40.3 >1780 >17000 <0.02 <0.01

Legume Vegetables W/Soybeans 

### MSsoybeanSTD_+165 37.6 >1780 >17000 <0.02 <0.01

Ornamentals:

Residential 

### CApervious/imperviousRLF 4.57 >1780 >17000 <0.01 <0.01

### 40

Ornamentals:

Nurseries 

### MInurserySTD_V2_+230 29.6 >1780 >17000 <0.02 <0.01

Peanut 

### NCpeanutSTD_+140 32.4 >1780 >17000 <0.02 <0.01

Pome Fruits 

### NCappleSTD_+35 19.3 >1780 >17000 <0.01 <0.01

Potato,

Tuberous/Corm Vegies 

### MEpotatoSTD_+120 50.2 >1780 >17000 <0.03 <0.01

Small Berries 

### CAWineGrapesRLF_V2_+150 13.3 >1780 >17000 <0.01 <0.01

Stone Fruits 

### MICherriesSTD_+80 20.2 >1780 >17000 <0.01 <0.01

Strawberry 

### CAStrawberrynonplasticRLF_V2_+5 40.7 >1780 >17000 <0.02 <0.01

Sugar beet 

### MNsugarbeetSTD_+10 34.1 >1780 >17000 <0.02 <0.01

Sunflower 

### CAcornOP_+140 18.1 >1780 >17000 <0.01 <0.01

Tree nuts 

### GAPecansSTD_+75 21.2 >1780 >17000 < 0.01 <0.01

Turf 

### PAturfSTD_+60 16.5 >1780 >17000 <0.01 <0.01

Chronic FW RQs Surface Water (EECs ug/L) Freshwater

Fish Freshwat

er

Invertebr

ates Freshwat

er Fish Freshwater

Invertebrates



### Crop Group/Crops Scenario Giving

the Highest EECs 21

- day 60

- day Chronic Chronic Chronic Chronic

Artichoke Artichoke 21.3 21.0 

### 135 1240 0.16 0.02

Beans & Peeas ILbeansNMC_+65 47.0 46.2 

### 135 1240 0.34 0.04

Brassica Leafy
Vegetables CAColeCropRLF_

V2_+65 36.7 36.0 

### 135 1240 0.27 0.03

Bulb Vegetables GAOnion_WirrigS

TD_+210 23.2 22.9 

### 135 1240 0.17 0.02

Canola NDcanolaSTD_+95 31.1 30.9 

### 135 1240 0.23 0.03

Carrot FLcarrotSTD_+0 38.3 36.4 

### 135 1240 0.27 0.03

Cereals: Corn and Sorghum MScornSTD_+135

&
KSCornStd_+160 49.3 48.2 

### 135 1240 0.36 0.04

Cereals: Wheat &

others TXwheatOP_+235 49.9 48.9 

### 135 1240 0.36 0.04

Christmas Trees Christmas Trees 6.8 6.7 

### 135 1240 0.05 0.01

Citrus FLcitrusSTD_+145 20.2 19.4 

### 135 1240 0.14 0.02

Cotton STXcottonNMC_+1

60 &

NCcottonSTD_+75 30.7 30.5 

### 135 1240 0.23 0.02

### 41

Cucurbits STXmelonNMC_+9

&
FLcucumberSTD_

+0 38.2 36.2 

### 135 1240 0.27 0.03

Fruiting Vegetables STXvegetableNMC

_+170 & FLpeppersSTD_+1

0 39.6 38.6 

### 135 1240 0.29 0.03

Ginseng MNsugarbeetSTD_

+10 33.7 33.3 

### 135 1240 0.25 0.03

Grapes & Small

Vine Fruits NYGrapesSTD_+9

0 19.4 19.2 

### 135 1240 0.14 0.02

Grasses for Forage/Seeds ORgrassseedSTD_

+160 21.0 20.6 

### 135 1240 0.15 0.02

Herbs & Spices CAColeCropRLF_

V2_+60 36.2 35.6 

### 135 1240 0.26 0.03

Hops ORhopsSTD_+140 23.7 23.5 

### 135 1240 0.17 0.02

Leafy Vegetables +

Petiole CAlettuceSTD_+95 39.8 39.2 

### 135 1240 0.29 0.03

Legume Vegetables W/Soybeans MSsoybeanSTD_+

165 37.2 37.1 

### 135 1240 0.27 0.03

Ornamentals:

Residential CApervious/imperv

iousRLF 4.5 4.4 

### 135 1240 0.03 0.00

Ornamentals:

Nurseries MInurserySTD_V2

_+230 29.3 29.4 

### 135 1240 0.22 0.02

Peanut NCpeanutSTD_+14

0 32.0 31.6 

### 135 1240 0.23 0.03

Pome Fruits NCappleSTD_+35 18.4 17.2 

### 135 1240 0.13 0.01

Potato,

Tuberous/Corm Vegies MEpotatoSTD_+12

0 49.9 49.6 

### 135 1240 0.37 0.04

Small Berries CAWineGrapesRL

F_V2_+150 13.4 13.1 

### 135 1240 0.10 0.01

Stone Fruits MICherriesSTD_+

80 20.0 19.7 

### 135 1240 0.15 0.02

Strawberry CAStrawberrynonp

lasticRLF_V2_+5 40.0 39.1 

### 135 1240 0.29 0.03

Sugar beet MNsugarbeetSTD_

+10 33.7 33.3 

### 135 1240 0.25 0.03

Sunflower CAcornOP_+140 17.8 17.6 

### 135 1240 0.13 0.01

Tree nuts GAPecansSTD_+7

5 21.2 21.3 

### 135 1240 0.16 0.02

Turf PAturfSTD_+60 16.2 15.8 

### 135 1240 0.12 0.01

### 42

Crop Group/Crops Scenario Giving the Highest EECs Peak

EEC
(ug
a.i./L) Saltwater

Invertebrates
EC/LC50 (ug
a.i./L) Saltwater

Invertebrates

Acute RQs*

Artichoke Artichoke 21.6 

### 510 0.04

Beans & Peeas ILbeansNMC_+65 47.8 

### 510 0.09

Brassica Leafy Vegetables CAColeCropRLF_V2_+65 37.3 

### 510 0.07

Bulb Vegetables GAOnion_WirrigSTD_+210 23.6 

### 510 0.05

Canola NDcanolaSTD_+95 31.5 

### 510 0.06

Carrot FLcarrotSTD_+0 40.2 

### 510 0.08

Cereals: Corn and Sorghum MScornSTD_+135 & KSCornStd_+160 50.1 

### 510 0.10

Cereals: Wheat & others TXwheatOP_+235 51.3 

### 510 0.10

Christmas Trees Christmas Trees 6.9 

### 510 0.01

Citrus FLcitrusSTD_+145 20.6 

### 510 0.04

Cotton STXcottonNMC_+160 &

NCcottonSTD_+75 31.7 

### 510 0.06

Cucurbits STXmelonNMC_+9 &
FLcucumberSTD_+0 39.2 

### 510 0.08

Fruiting Vegetables STXvegetableNMC_+170 & FLpeppersSTD_+10 40.7 

### 510 0.08

Ginseng MNsugarbeetSTD_+10 34.1 

### 510 0.07

Grapes & Small Vine Fruits NYGrapesSTD_+90 19.6 

### 510 0.04

Grasses for Forage/Seeds ORgrassseedSTD_+160 21.4 

### 510 0.04

Herbs & Spices CAColeCropRLF_V2_+60 36.7 

### 510 0.07

Hops ORhopsSTD_+140 24.0 

### 510 0.05

Leafy Vegetables + Petiole CAlettuceSTD_+95 40.3 

### 510 0.08

Legume Vegetables W/Soybeans MSsoybeanSTD_+165 37.6 

### 510 0.07

Ornamentals: Residential CApervious/imperviousRLF 4.6 

### 510 0.01

Ornamentals: Nurseries MInurserySTD_V2_+230 29.6 

### 510 0.06

Peanut NCpeanutSTD_+140 32.4 

### 510 0.06

Pome Fruits NCappleSTD_+35 19.3 

### 510 0.04

Potato, Tuberous/Corm Vegies MEpotatoSTD_+120 50.2 

### 510 0.10

Small Berries CAWineGrapesRLF_V2_+150 13.3 

### 510 0.03

Stone Fruits MICherriesSTD_+80 20.2 

### 510 0.04

Strawberry CAStrawberrynonplasticRLF_V2_+5 40.7 

### 510 0.08

Sugar beet MNsugarbeetSTD_+10 34.1 

### 510 0.07

Sunflower CAcornOP_+140 18.1 

### 510 0.04

Tree nuts GAPecansSTD_+75 21.2 

### 510 0.04

Turf PAturfSTD_+60 16.5 

### 510 0.03


### *All RQs are less than the value presented since the toxicity endpoint is greater than 510 ug a.i./L

Endpoints RQs

### 43

Crop Group/Crops Scenario Giving the Highest EECs Peak
EEC (ug
a.i./L) Nonvascular

Aquatic

Plant Nonvascular

Aquatic

Plant Nonvascular

Aquatic

Plant Nonvascular

Aquatic

Plant

Acute Chronic nonlisted listed

Artichoke Artichoke 21.6 

### 3400 1170 0.01 0.02

Beans & Peeas ILbeansNMC_+65 47.8 

### 3400 1170 0.01 0.04

Brassica Leafy Vegetables CAColeCropRLF_V2_+65 37.3 

### 3400 1170 0.01 0.03

Bulb Vegetables GAOnion_WirrigSTD_+210 23.6 

### 3400 1170 0.01 0.02

Canola NDcanolaSTD_+95 31.5 

### 3400 1170 0.01 0.03

Carrot FLcarrotSTD_+0 40.2 

### 3400 1170 0.01 0.03

Cereals: Corn and Sorghum MScornSTD_+135 &
KSCornStd_+160 50.1 

### 3400 1170 0.01 0.04

Cereals: Wheat & others TXwheatOP_+235 51.3 

### 3400 1170 0.02 0.04

Christmas Trees Christmas Trees 6.9 

### 3400 1170 0.00 0.01

Citrus FLcitrusSTD_+145 20.6 

### 3400 1170 0.01 0.02

Cotton STXcottonNMC_+160 &

NCcottonSTD_+75 31.7 

### 3400 1170 0.01 0.03

Cucurbits STXmelonNMC_+9 &
FLcucumberSTD_+0 39.2 

### 3400 1170 0.01 0.03

Fruiting Vegetables STXvegetableNMC_+170 & FLpeppersSTD_+10 40.7 

### 3400 1170 0.01 0.03

Ginseng MNsugarbeetSTD_+10 34.1 

### 3400 1170 0.01 0.03

Grapes & Small Vine Fruits NYGrapesSTD_+90 19.6 

### 3400 1170 0.01 0.02

Grasses for Forage/Seeds ORgrassseedSTD_+160 21.4 

### 3400 1170 0.01 0.02

Herbs & Spices CAColeCropRLF_V2_+60 36.7 

### 3400 1170 0.01 0.03

Hops ORhopsSTD_+140 24.0 

### 3400 1170 0.01 0.02

Leafy Vegetables + Petiole CAlettuceSTD_+95 40.3 

### 3400 1170 0.01 0.03

Legume Vegetables W/Soybeans MSsoybeanSTD_+165 37.6 

### 3400 1170 0.01 0.03

Ornamentals: Residential CApervious/imperviousRLF 4.6 

### 3400 1170 0.00 0.00

Ornamentals: Nurseries MInurserySTD_V2_+230 29.6 

### 3400 1170 0.01 0.03

Peanut NCpeanutSTD_+140 32.4 

### 3400 1170 0.01 0.03

Pome Fruits NCappleSTD_+35 19.3 

### 3400 1170 0.01 0.02

Potato, Tuberous/Corm Vegies MEpotatoSTD_+120 50.2 

### 3400 1170 0.01 0.04

Small Berries CAWineGrapesRLF_V2_+150 13.3 

### 3400 1170 0.00 0.01

Stone Fruits MICherriesSTD_+80 20.2 

### 3400 1170 0.01 0.02

Strawberry CAStrawberrynonplasticRLF_V2_+5 40.7 

### 3400 1170 0.01 0.03

Sugar beet MNsugarbeetSTD_+10 34.1 

### 3400 1170 0.01 0.03

Sunflower CAcornOP_+140 18.1 

### 3400 1170 0.01 0.02

Tree nuts GAPecansSTD_+75 21.2 

### 3400 1170 0.01 0.02

Turf PAturfSTD_+60 16.5 

### 3400 1170 0.00 0.01

Endpoints RQs

### 44

Crop Group/Crops Scenario Giving the Highest EECs Peak
EEC (ug
a.i./L) Vascular

Aquatic

Plant Vascular

Aquatic

Plant Vascular

Aquatic

Plant Vascular

Aquatic

Plant

Acute Chronic nonlisted listed

Artichoke Artichoke 21.6 

### 2600 278 0.01 0.08

Beans & Peeas ILbeansNMC_+65 47.8 

### 2600 278 0.02 0.17

Brassica Leafy Vegetables CAColeCropRLF_V2_+65 37.3 

### 2600 278 0.01 0.13

Bulb Vegetables GAOnion_WirrigSTD_+210 23.6 

### 2600 278 0.01 0.08

Canola NDcanolaSTD_+95 31.5 

### 2600 278 0.01 0.11

Carrot FLcarrotSTD_+0 40.2 

### 2600 278 0.02 0.14

Cereals: Corn and Sorghum MScornSTD_+135 &
KSCornStd_+160 50.1 

### 2600 278 0.02 0.18

Cereals: Wheat & others TXwheatOP_+235 51.3 

### 2600 278 0.02 0.18

Christmas Trees Christmas Trees 6.9 

### 2600 278 0.00 0.02

Citrus FLcitrusSTD_+145 20.6 

### 2600 278 0.01 0.07

Cotton STXcottonNMC_+160 &

NCcottonSTD_+75 31.7 

### 2600 278 0.01 0.11

Cucurbits STXmelonNMC_+9 &
FLcucumberSTD_+0 39.2 

### 2600 278 0.02 0.14

Fruiting Vegetables STXvegetableNMC_+170 & FLpeppersSTD_+10 40.7 

### 2600 278 0.02 0.15

Ginseng MNsugarbeetSTD_+10 34.1 

### 2600 278 0.01 0.12

Grapes & Small Vine Fruits NYGrapesSTD_+90 19.6 

### 2600 278 0.01 0.07

Grasses for Forage/Seeds ORgrassseedSTD_+160 21.4 

### 2600 278 0.01 0.08

Herbs & Spices CAColeCropRLF_V2_+60 36.7 

### 2600 278 0.01 0.13

Hops ORhopsSTD_+140 24.0 

### 2600 278 0.01 0.09

Leafy Vegetables + Petiole CAlettuceSTD_+95 40.3 

### 2600 278 0.02 0.14

Legume Vegetables W/Soybeans MSsoybeanSTD_+165 37.6 

### 2600 278 0.01 0.14

Ornamentals: Residential CApervious/imperviousRLF 4.6 

### 2600 278 0.00 0.02

Ornamentals: Nurseries MInurserySTD_V2_+230 29.6 

### 2600 278 0.01 0.11

Peanut NCpeanutSTD_+140 32.4 

### 2600 278 0.01 0.12

Pome Fruits NCappleSTD_+35 19.3 

### 2600 278 0.01 0.07

Potato, Tuberous/Corm Vegies MEpotatoSTD_+120 50.2 

### 2600 278 0.02 0.18

Small Berries CAWineGrapesRLF_V2_+150 13.3 

### 2600 278 0.01 0.05

Stone Fruits MICherriesSTD_+80 20.2 

### 2600 278 0.01 0.07

Strawberry CAStrawberrynonplasticRLF_V2_+5 40.7 

### 2600 278 0.02 0.15

Sugar beet MNsugarbeetSTD_+10 34.1 

### 2600 278 0.01 0.12

Sunflower CAcornOP_+140 18.1 

### 2600 278 0.01 0.07

Tree nuts GAPecansSTD_+75 21.2 

### 2600 278 0.01 0.08

Turf PAturfSTD_+60 16.5 

### 2600 278 0.01 0.06

### 45

Chronic FW

RQs EECs (ug/L) Endpoints Chronic

Porewater

Freshwater

Invert Chronic

Porewater

Saltwater

Inver



### Crop Group/Crops Scenario Giving the Highest EECs Porewater FW Sed

Invert SW Sed

Invert Chronic RQ

Artichoke Artichoke 

### 19.9 3800 7500 0.01 0.00

Beans & Peeas ILbeansNMC_+65 44.4 

### 3800 7500 0.01 0.01

Brassica Leafy
Vegetables CAColeCropRLF_V2_+65 34.6 

### 3800 7500 0.01 0.00

Bulb Vegetables GAOnion_WirrigSTD_+210 21.5 

### 3800 7500 0.01 0.00

Canola NDcanolaSTD_+95 

### 30.3 3800 7500 0.01 0.00

Carrot FLcarrotSTD_+0 

### 32.6 3800 7500 0.01 0.00

Cereals: Corn and Sorghum MScornSTD_+135 &
KSCornStd_+160 46.4 

### 3800 7500 0.01 0.01

Cereals: Wheat

& others TXwheatOP_+235 44.9 

### 3800 7500 0.01 0.01

Christmas

Trees Christmas Trees 

### 6.4 3800 7500 0.00 0.00

Citrus FLcitrusSTD_+145 17.4 

### 3800 7500 0.00 0.00

Cotton STXcottonNMC_+160 &

NCcottonSTD_+75 29.8



### 3800 7500 0.01 0.00

Cucurbits STXmelonNMC_+9 &

FLcucumberSTD_+0 32.5



### 3800 7500 0.01 0.00

Fruiting Vegetables STXvegetableNMC_+170 &

FLpeppersSTD_+10 34.8



### 3800 7500 0.01 0.00

Ginseng MNsugarbeetSTD_+10 

### 32.2 3800 7500 0.01 0.00

Grapes & Small

Vine Fruits NYGrapesSTD_+90 19.0 

### 3800 7500 0.01 0.00

Grasses for Forage/Seeds ORgrassseedSTD_+160 19.4 

### 3800 7500 0.01 0.00

Herbs & Spices CAColeCropRLF_V2_+60 34.1 

### 3800 7500 0.01 0.00

Hops ORhopsSTD_+140 

### 22.9 3800 7500 0.01 0.00

Leafy Vegetables +

Petiole CAlettuceSTD_+95 38.1



### 3800 7500 0.01 0.01

### 46 Legume Vegetables W/Soybeans MSsoybeanSTD_+165 35.4 

### 3800 7500 0.01 0.00

Ornamentals:

Residential CApervious/imperviousRLF 

### 3800 7500 0.00 0.00

Ornamentals:

Nurseries MInurserySTD_V2_+230 28.4 

### 3800 7500 0.01 0.00

Peanut NCpeanutSTD_+140 

### 29.8 3800 7500 0.01 0.00

Pome Fruits NCappleSTD_+35 15.4 

### 3800 7500 0.00 0.00

Potato,

Tuberous/Corm Vegies MEpotatoSTD_+120 49.0



### 3800 7500 0.01 0.01

Small Berries CAWineGrapesRLF_V2_+150 12.5 

### 3800 7500 0.00 0.00

Stone Fruits MICherriesSTD_+80 19.5 

### 3800 7500 0.01 0.00

Strawberry CAStrawberrynonplasticRLF_V2_+5 36.3 

### 3800 7500 0.01 0.00

Sugar beet MNsugarbeetSTD_+10 32.2 

### 3800 7500 0.01 0.00

Sunflower CAcornOP_+140 

### 16.9 3800 7500 0.00 0.00

Tree nuts GAPecansSTD_+75 21.1 

### 3800 7500 0.01 0.00

Turf PAturfSTD_+60 15.6 

### 3800 7500 0.00 0.00

Chronic FW

RQs Endpoints Chronic

Sediment

Freshwater

Invert Chronic

Sediment

Saltwater

Inver



### Crop Group/Crops Scenario Giving the Highest EECs Sediment FW Sed

Invert SW Sed

Invert Chronic RQs

Artichoke Artichoke 

### 356 26000 100000 0.01 0.00

Beans & Peeas ILbeansNMC_+65 795 

### 26000 100000 0.03 0.01

Brassica Leafy
Vegetables CAColeCropRLF_V2_+65 619 

### 26000 100000 0.02 0.01

Bulb Vegetables GAOnion_WirrigSTD_+210 385 

### 26000 100000 0.01 0.00

Canola NDcanolaSTD_+95 

### 542 26000 100000 0.02 0.01

Carrot FLcarrotSTD_+0 

### 584 26000 100000 0.02 0.01

Cereals: Corn and Sorghum MScornSTD_+135 &
KSCornStd_+160 831 

### 26000 100000 0.03 0.01

Cereals: Wheat

& others TXwheatOP_+235 804 

### 26000 100000 0.03 0.01

### 47

Christmas

Trees Christmas Trees 

### 115 26000 100000 0.00 0.00

Citrus FLcitrusSTD_+145 311 

### 26000 100000 0.01 0.00

Cotton STXcottonNMC_+160 &

NCcottonSTD_+75 533



### 26000 100000 0.02 0.01

Cucurbits STXmelonNMC_+9 &

FLcucumberSTD_+0 582



### 26000 100000 0.02 0.01

Fruiting
Vegetables STXvegetableNMC_+170 &

FLpeppersSTD_+10 623



### 26000 100000 0.02 0.01

Ginseng MNsugarbeetSTD_+10 

### 576 26000 100000 0.02 0.01

Grapes & Small

Vine Fruits NYGrapesSTD_+90 340 

### 26000 100000 0.01 0.00

Grasses for Forage/Seeds ORgrassseedSTD_+160 347 

### 26000 100000 0.01 0.00

Herbs & Spices CAColeCropRLF_V2_+60 610 

### 26000 100000 0.02 0.01

Hops ORhopsSTD_+140 

### 410 26000 100000 0.02 0.00

Leafy
Vegetables +

Petiole CAlettuceSTD_+95 682



### 26000 100000 0.03 0.01

Legume Vegetables W/Soybeans MSsoybeanSTD_+165 634 

### 26000 100000 0.02 0.01

Ornamentals:

Residential CApervious/imperviousRLF 

### 26000 100000 0.00 0.00

Ornamentals:

Nurseries MInurserySTD_V2_+230 508 

### 26000 100000 0.02 0.01

Peanut NCpeanutSTD_+140 

### 533 26000 100000 0.02 0.01

Pome Fruits NCappleSTD_+35 276 

### 26000 100000 0.01 0.00

Potato,

Tuberous/Corm Vegies MEpotatoSTD_+120 877



### 26000 100000 0.03 0.01

Small Berries CAWineGrapesRLF_V2_+150 224 

### 26000 100000 0.01 0.00

Stone Fruits MICherriesSTD_+80 349 

### 26000 100000 0.01 0.00

Strawberry CAStrawberrynonplasticRLF_V2_+5 650 

### 26000 100000 0.02 0.01

Sugar beet MNsugarbeetSTD_+10 576 

### 26000 100000 0.02 0.01

Sunflower CAcornOP_+140 

### 303 26000 100000 0.01 0.00

Tree nuts GAPecansSTD_+75 378 

### 26000 100000 0.01 0.00

### 48 Turf PAturfSTD_+60 279 

### 26000 100000 0.01 0.00



# Appendix 3 : Calculation of the Seed Treatment Applciation rates and an Example T

- Rex Run for Peanut Seed

- Treatment

Chemical Name: Fluopyram ST Application Rate (lb ai/acre)

Seed Treatment? (Check if yes) TRUE Seeding Rate (lbs/acre)

Use: 5 18.9

Product name and

form: Fluopyram ST % A.I. (leading zero

must be entered for formulations <1% a.i.): 100.00% Application rate (fl

oz/cwt) 

### 3.83

Half

- life (days): 

### 35

Application Interval

(days): 

### 0

Number of Applications: 

### 1

Are you assessing applications with

variable rates or

intervals? 

### no



## Endpoints Reported Tested Body Adjusted LD50 Size class for adjusted LD50 Weight (g)

Avian LD50: 2000.00 178 1440.86 Small (20g) Avian repro.

NOAEC: 46.70 1834.29 Medium (100g)

2591.00 Large (1000g)

Mammalian

LD50: 2000.00 350 4395.66 Small (15g)

Mammalian

NOAEL: 260.00 3556.56 Medium (35g)

1538.32 Large (1000g)

Adjusted NOAEL for Mammals

Small (15g) 28.57
Medium (35g) 23.12

### 49 Large (1000g) 10.00

Maximum Application

Rate Maximum Seed

Application

Rate Avian Nagy

Dose Mammalian

Nagy Dose Available

AI

(lbs ai/A) (mg ai/kg seed) (mg ai/kg

bw/day) (mg ai/kg

bw/day) (mg ai ft

- 2)

0.03 1496.09 378.64 316.98

0.29 215.92 219.08

96.67 50.79

Risk Quotients†

Avian (20 g) Mammalian (15 g)

Acute (# 1) Acute (# 2) Chronic Acute (# 1) Acute (# 2) Chronic

0.26 0.01 32.04 0.07 0.00 11.09

Avian (100 g) Mammalian (35 g)

Acute (# 1) Acute (# 2) Chronic Acute (# 1) Acute (# 2) Chronic

0.12 0.00 32.04 0.06 0.00 9.48

Avian (1000 g) Mammalian (1000 g)

Acute (# 1) Acute (# 2) Chronic Acute (# 1) Acute (# 2) Chronic

0.04 0.00 32.04 0.03 0.00 5.08

### 50



# Appendix 4 : Calculation of the EECs and RQs from Spray Treatment Appl ic ation rates and an Example T

- Rex Run for the maximum application rate

Chemical Name: Fluopyram ST

Use 0

Formulation Privelege

Application Rate 0.25 lbs a.i./acre

Half

- life 35 days

Application Interval 5 days

Maximum # Apps./Year 2

Length of Simulation 1 year
Variable application rates? no



## Endpoints



# Avian Bobwhite quail LD50 (mg/kg

- bw) 2000.00

Mallard duck) LC50 (mg/kg

- diet) 4604.00

Bobwhite quail NOAEL(mg/kg

- bw) 0.00

Bobwhite quail NOAEC (mg/kg

- diet) 46.70



# Mammals LD50 (mg/kg

- bw) 2000.00
LC50 (mg/kg

- diet) 0.00
NOAEL (mg/kg

- bw) 13.00

NOAEC (mg/kg

- diet) 260.00



# Dietary

- based EECs

(ppm) Kenaga

Values

Short Grass 114.34

Tall Grass 52.41
Broadleaf plants 64.32 Fruits/pods/seeds 7.15

Arthropods 44.78

### 51 Avian Body Ingestion (Fdry) Ingestion

(Fwet) % body wgt FI

Class Weight (g) (g bw/day) (g/day) consumed (kg

- diet/day)

Small 20 5 23 114 2.28E

- 02

Mid 100 13 65 65 6.49E

- 02

Large 1000 58 291 29 2.91E

- 01

20 5 5 25 5.06E

- 03

Granivores 100 13 14 14 1.44E

- 02

1000 58 65 6 6.46E

- 02

Avian Body Adjusted LD50

Weight (g) (mg/kg

- bw)

20 1440.86

100 1834.29

1000 2591.00



# Dose

- based EECs

(mg/kg

- bw) Avian Classes and Body Weights (grams)

small mid large

20 100 1000

Short Grass 130.23 74.26 33.25

Tall Grass 59.69 34.04 15.24
Broadleaf plants 73.25 41.77 18.70
Fruits/pods 8.14 4.64 2.08
Arthropods 51.01 29.09 13.02

Seeds 1.81 1.03 0.46



# Dose

- based RQs

(Dose

- based EEC/adjusted LD50) Avian Acute RQs Size Class (grams)

20 100 1000

Short Grass 0.09 0.04 0.01

Tall Grass 0.04 0.02 0.01
Broadleaf plants 0.05 0.02 0.01
Fruits/pods 0.01 0.00 0.00
Arthropods 0.04 0.02 0.01

Seeds 0.00 0.00 0.00

### 52



# Dietary

- based RQs

(Dietary

- based EEC/LC50 or NOAEC) RQs

Acute Chronic

Short Grass 0.02 2.45

Tall Grass 0.01 1.12
Broadleaf plants 0.01 1.38
Fruits/pods/seeds 0.00 0.15

Arthropods 0.01 0.96

Mammalian Body Ingestion (Fdry) Ingestion

(Fwet) % body wgt FI

Class Weight (g bwt/day) (g/day) consumed (kg

- diet/day)

15 3 14 95 1.43E

- 02

Herbivores/ 35 5 23 66 2.31E

- 02

insectivores 1000 31 153 15 1.53E

- 01

15 3 3 21 3.18E

- 03

Grainvores 35 5 5 15 5.13E

- 03

1000 31 34 3 3.40E

- 02

Mammalian Body Adjusted Adjusted

Class Weight LD50 NOAEL

15 4395.66 28.57

Herbivores/ 35 3556.56 23.12

insectivores 1000 1538.32 10.00

15 4395.66 28.57

Granivores 35 3556.56 23.12

1000 1538.32 10.00



# Dose

- Based EECs

(mg/kg

- bw) Mammalian Classes and Body weight

(grams)

15 35 1000

Short Grass 109.02 75.35 17.47

Tall Grass 49.97 34.53 8.01
Broadleaf plants 61.32 42.38 9.83
Fruits/pods 6.81 4.71 1.09
Arthropods 42.70 29.51 6.84

Seeds 1.51 1.05 0.24

### 53 

# Dose

based

RQs

(Dose

- based

EEC/LD50 or NOAEL) Small mammal Medium mammal Large mammal

15 grams 35 grams 1000 grams

Acute Chro nic Acute Chronic Acute Chronic

Short Grass 0.02 3.82 0.02 3.26 0.01 1.75

Tall Grass 0.01 1.75 0.01 1.49 0.01 0.80
Broadleaf plants 0.01 2.15 0.01 1.83 0.01 0.98 Fruits/pods 0.00 0.24 0.00 0.20 0.00 0.11
Arthropods 0.01 1.49 0.01 1.28 0.00 0.68

Seeds 0.00 0.05 0.00 0.05 0.00 0.02



# Dietary

- based RQs

(Dietary

- based EEC/LC50 or NOAEC) Mammal RQs

Acute Chronic

Short Grass #DIV/0! 0.44

Tall Grass #DIV/0! 0.20
Broadleaf plants #DIV/0! 0.25
Fruits/pods/seeds #DIV/0! 0.03

Arthropods #DIV/0! 0.17