### Publically **available information on diisocyanates** 

1. In fall 2009, EPA hosted a webinar presentation on "What You Need to Know a bout the Safe Use of Spray

Pol yurethane Foam (SPF)", with participants from OSHA, NIOSH, CPSC, and industry available online at: http://www.epa.gov/dfe/spf_presentation_2009_epa_osha_niosh_cpsc.pdf 2. The Design for the Environment Program has a history of development of best p ractices working with isocy anates in the automotive refinishing industry . Isoc yanates are also a key component of SPF. Please see EPA's Design fo r the Environment Program site available online at: h ttp://www.epa.gov/dfe/best_practices.html for links to additional publically available resources. The DfE Program hopes to provide a similar information page for SPF and other isocy anate uses. 3. Health and safet y information: CPSC - an incident repo rt on SPF available online at: http://www.saferproducts.gov/ViewIncident/1193994

- NI OSH Health & Saf

ety Topic Page on Isocy anates available online at: http://www.cdc.gov/niosh/topics/isocy anates/

- OSHA Safet y & Hea lth Topic page on Isocy anates available online at: http://www.osha.gov/ SL TC/isocy anates/index.html

- NI OSH ALERT, NIOSH Publication No. 2006 - 149 Preventing Asthma and Death from MDI Exposure During Spray - on Truck Bed Liner and Related Applications available online at: http://www.cdc.gov/niosh/docs/2006 - 149/default.html

- NI OSH ALERT 1996: Preventing Asthma and Death from Diisocy anates Exposure available online at: http://www.cdc.gov/niosh/asthma.html

- Method for measuring volatile chemicals is the standard method under California Section 01350 .

- ASTM International, an organization that sets standards for products and mater ials, has initiated development of a standard (D22.05) to determine volatile organic compounds, diisocy anates, oligomeric isocy anates, and amine cataly sts emitted from SPF insulation pro ducts designed for on - site application in buildings (ASTM WK30960) .

- Manufacturer's Material Safety Data Sheets - ava ilable from the manufacturers. Some are available online at the US Department of Health and Human Services’ Household Products Database .- Integrated Risk Information Sy stem (I RI S) report on Methy lene Diphenyl Diisocy anate

(monomeric MDI) and poly meric MDI (PMDI); CASRN 101 - 68 - 8, 9 016 - 87 - 9 (02/07/1998) available online at: http://www.epa.gov/iris/subst/0529.htm

- EPA's New Chemical Program C hemical Category on Isocy anates available online at: http://www.epa.gov/dfe/pubs/auto/profile/appa.pdf

- Toxic Substances Control Act Section 8(e) Notices of Substantial Risk & FYI Notices: Poly meric MDI

– Resul ts of a modified local l ymph node assay in mice (PDF) (28 pp., 839 KB, about PDF ) Blocked Aromatic Isocy anate (PDF) ( 1 pp, 38 KB, about PDF ) 4,4' - Methy lenedianiline (MDA) (PDF) (80 pp, 2.28 MB, about PDF ) Isocy anates (Emissions from fires) (PDF) (130 pp, 10 MB, about PDF ) “Fatalities L inked to Diisocy anates” (PDF) (16 pp, 1.42MB, about PDF ) Dipheny lmethane - 4,4' - diisocy anate (Pol ym eric MDI) (PDF) (47 pp, 3.56MB, about PDF ) 4. Industry

Resources:

- Ba ye r Material Science Residential SPF Survey available online at: http://www.spray foam.org/uploads/pages/4507/SPFA - CPI %20Emissions.pdf

- Ba ye r Material Science study entitled "A Proposed Methodology for Development of Building Re - Occupancy

Guidelines Following Installation of Spray Poly urethane Foam Insulation" available online at: http://www.bay careonline.com/ums/import - export/nafta_479.pdf