Exhibit
12.1
 
 Computation
of
 Ratio of
Earnings to Fixed Charges
 
 Year Ended December 31,(amounts in thousands)
                      
                      2009
                      
                      
                      2008
                      
                      
                      2007
                      
                      
                      2006
                      
                      
                      2005Loss
      before income taxes$
                      (11,166
                      )
                      
                      $
                      (16,556
                      )
                      
                      $
                      (19,429
                      )
                      
                      $
                      (10,742
                      )
                      
                      $
                      (23,445
                      )Plus
      fixed charges:Interest
      expense
                      
                      
                      577
                      
                      
                      
                      1,374
                      
                      
                      
                      2,070
                      
                      
                      
                      2,047
                      
                      
                      
                      4,623Amortization
      of costs related to indebtedness
                      
                      
                      210
                      
                      
                      
                      567
                      
                      
                      
                      1,536
                      
                      
                      
                      2,308
                      
                      
                      
                      5,521Estimated
      interest factor in rent expense (1)
                      
                      
                      501
                      
                      
                      
                      660
                      
                      
                      
                      512
                      
                      
                      
                      482
                      
                      
                      
                      391Total
      Fixed Charges
                      
                      
                      1,288
                      
                      
                      
                      2,601
                      
                      
                      
                      4,118
                      
                      
                      
                      4,837
                      
                      
                      
                      10,535Adjusted
      loss
                      
                      
                      (9,878
                      )
                      
                      
                      (13,955
                      )
                      
                      
                      (15,311
                      )
                      
                      
                      (5,905
                      )
                      
                      
                      (12,910
                      )Fixed
      charges
                      
                      
                      1,288
                      
                      
                      
                      2,601
                      
                      
                      
                      4,118
                      
                      
                      
                      4,837
                      
                      
                      
                      10,535Deficiency
      in earnings to cover fixed charges
                      
                      $
                      (11,166
                      )
                      
                      $
                      (16,556
                      )
                      
                      $
                      (19,429
                      )
                      
                      $
                      (10,742
                      )
                      
                      $
                      (23,445
                      )Ratio
      of earnings to fixed charges
                      
                      
                      *
                      
                      
                      
                      *
                      
                      
                      
                      *
                      
                      
                      
                      *
                      
                      
                      
                      *
 
 *
Calculation not meaningful as ratio is less than 1.
 (1) The
interest factor in rent expense is estimated as one-third of rental
expense.