II 

109TH CONGRESS 

1ST SESSION S. 2115 

To amend the Public Health Service Act to improve provisions relating to 

Parkinson’s disease research. 

IN THE SENATE OF THE UNITED STATES 

DECEMBER 15, 2005 

Ms. STABENOW (for herself, Mr. SMITH, Mr. LAUTENBERG, Mrs. MURRAY, 

Mr. MCCAIN, Mr. COLEMAN, and Mr. DAYTON) introduced the following 

bill; which was read twice and referred to the Committee on Health, Education, Labor, and Pensions 

A BILL 

To amend the Public Health Service Act to improve 

provisions relating to Parkinson’s disease research. 

1 Be it enacted by the Senate and House of Representa2 tives of the United States of America in Congress assembled, 

3 SECTION 1. SHORT TITLE. 

4 This Act may be cited as the ‘‘Morris K. Udall Par5 kinson’s Disease Research Act Amendments of 2005’’. 

6 SEC. 2. MORRIS K. UDALL PARKINSON’S DISEASE RE7 SEARCH ACT OF 1997. 

8 (a) FINDINGS.—Subsection (b) of section 603 of the 

9 Morris K. Udall Parkinson’s Disease Research Act of 
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1 1977 (42 U.S.C. 284f note) is amended by striking para2 graph (1) and inserting the following: 

3 ‘‘(1) FINDING.—Congress finds that, to take 

4 full advantage of the tremendous potential for find5 ing a cure or effective treatment, the Federal invest6 ment in Parkinson’s must be expanded, as well as 

7 the coordination strengthened among the National 

8 Institutes of Health research institutes.’’. 

9 (b) PUBLIC HEALTH SERVICE ACT.—Section 409B 

10 of the Public Health Service Act (42 U.S.C. 284f) is 

11 amended— 

12 (1) in subsection (b), by striking paragraph (2) 

13 and inserting the following: 

14 ‘‘(2) CONFERENCE.— 

15 ‘‘(A) IN GENERAL.—The Director of NIH 

16 shall convene a coordinating and planning con17 ference every 2 years with relevant institutes 

18 and non-governmental organizations to conduct 

19 a thorough investigation of all Parkinson’s re20 search that is funded in whole or in part by the 

21 National Institutes of Health and to identify 

22 shortcomings and opportunities for more effec23 tive treatments and a cure for Parkinson’s dis24 ease. The Director shall report to Congress on 
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1 the coordination among the institutes in car2 rying out such research. 

3 ‘‘(B) RESEARCH INVESTMENT PLAN.— 

4 ‘‘(i) IN GENERAL.—The results of 

5 each conference convened under subpara6 graph (A) shall be included in a research 

7 investment plan that provides for measur8 able results with the goals of better treat9 ments and a cure for Parkinson’s disease 

10 being the determining factors in the alloca11 tion of Parkinson’s disease research dol12 lars. The plan shall include an outline of 

13 the manner in which to fully utilize the 

14 Udall Center program to ensure the con15 tinuation of a particular focus on 

16 translational research, including a clinical 

17 component. 

18 ‘‘(ii) BUDGET AND IMPLEMENTATION

19 STRATEGY.—The plan submitted under 

20 clause (i) shall include a budget (that in21 cludes both programmatic and dollar line 

22 items) and implementation strategy (that 

23 incorporates the use of special initiatives 

24 such as Requests for Applications, Pro25 gram Announcements with set-asides or 
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1 similar directed research mechanisms) to2 gether with results to be reported back to 

3 Congress. 

4 ‘‘(C) SUBMISSIONS TO CONGRESS.—The 

5 plan under subparagraph (B) (including the 

6 budget and implementation strategy) and the 

7 expected results of plan implementation shall be 

8 submitted to Congress not later than 3 months 

9 after the conference is convened under subpara10 graph (A). Reports on the outcomes of the plan, 

11 including actual spending and actual results, 

12 shall be submitted to Congress on an annual 

13 basis. 

14 ‘‘(D) FUNDING.—The Secretary shall en15 sure that adequate funding is available under 

16 this section to carry out the activities described 

17 in the investment plan under subparagraph 

18 (B).’’; 

19 (2) in subsection (c)— 

20 (A) in paragraph (1)— 

21 (i) by striking ‘‘not more than 10’’; 

22 and 

23 (ii) by adding at the end the fol24 lowing: ‘‘The Director shall ensure that an 

25 additional center shall be funded under 
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1 this paragraph to serve as the coordinating 

2 center to coordinate the activities con3 ducted by each of the centers funded under 

4 this paragraph to further focus and man5 age the interdisciplinary efforts of such 

6 centers.’’; 

7 (B) in paragraph (2)(A)(ii), by striking 

8 ‘‘conduct basic and clinical research’’ and in9 serting ‘‘in carrying out research, ensure that a 

10 significant clinical component is provided for in 

11 addition to ongoing basic research’’; and 

12 (C) by adding at the end the following: 

13 ‘‘(5) REVIEW PROCESS.—The Director of NIH 

14 shall establish a review process with respect to appli15 cations received for grants under paragraph (1). 

16 Such process shall provide for the evaluation of ap17 plicants in a manner that recognizes the unique as18 pects of the clinical, coordination, and multidisci19 plinary components of the applicants.’’; 

20 (3) in subsection (d)— 

21 (A) by striking ‘‘is authorized to establish 

22 a grant program’’ and inserting ‘‘shall award 

23 grants’’; and 

24 (B) by inserting before the period at the 

25 end the following: ‘‘and shall be awarded in a 
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1 manner consistent with the research investment 

2 plan under subsection (b)(2)(B)’’; and 

3 (4) by striking subsection (e) and inserting the 

4 following: 

5 ‘‘(e) REPORT.—The Director of NIH, in consultation 

6 with the Director of the Centers for Disease Control and 

7 Prevention, shall conduct an investigation, and prepare 

8 and submit to the appropriate committees of Congress a 

9 report, on the incidence of Parkinson’s disease, including 

10 age, occupation, and geographic population clusters, and 

11 related environmental factors relating to such disease. 

12 ‘‘(f) AUTHORIZATION OF APPROPRIATIONS.—For the 

13 purposes of carrying out this section, section 301, and this 

14 title with respect to research focused on Parkinson’s dis15 ease, there are authorized to be appropriated not to exceed 

16 such sums as may be necessary for each of fiscal years 

17 2007 through 2012.’’. 

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