**EXHIBIT 31.1**

 

**CERTIFICATIONPURSUANT TO SECTION 302**

**OF THESARBANES-OXLEY ACT OF 2002**

 

I, Stanislaw R. Burzynski, certify that:

 

1.             Ihave reviewed this annual report on Form 10-KSB of Burzynski ResearchInstitute, Inc. (“BRI”);

 

2.             Basedon my knowledge, this report does not contain any untrue statement of amaterial fact or omit to state a material fact necessary to make the statementsmade, in light of the circumstances under which such statements were made, notmisleading with respect to the period covered by this report;

 

3.             Basedon my knowledge, the financial statements, and other financial informationincluded in this report, fairly present in all material respects the financialcondition, results of operations and cash flows of BRI as of, and for, theperiods presented in this report;

 

4.             Iam responsible for establishing and maintaining disclosure controls andprocedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e))for BRI and have:

 

### **(a)           Designed such disclosure controls andprocedures, or caused such disclosure controls and procedures to be designedunder my supervision, to ensure that material information relating to BRI,including its consolidated subsidiaries, is made known to me by others withinthose entities, particularly during the period in which this report is beingprepared;**

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### **(b)           Evaluated the effectiveness of BRI’sdisclosure controls and procedures and presented in this report my conclusionsabout the effectiveness of the disclosure controls and procedures, as of theend of the period covered by this report based on such evaluation; and**

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### **(c)           Disclosed in this report any changein BRI’s internal control over financial reporting that occurred during BRI’smost recent fiscal quarter (BRI’s fourth fiscal quarter in the case of anannual report) that has materially affected, or is reasonably likely tomaterially affect, BRI’s internal control over financial reporting;**

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5.             Ihave disclosed, based on my most recent evaluation of internal control overfinancial reporting, to BRI’s auditors and BRI’s board of directors (or personsperforming the equivalent functions of an audit committee):

 

### **(a)           All significant deficiencies andmaterial weaknesses in the design or operation of internal control overfinancial reporting which are reasonably likely to adversely affect BRI’s**abilityto record, process, summarize and report financial information; and

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### **(b)           Any fraud, whether or not material,that involves management or other employees who have a significant role in BRI’sinternal control over financial reporting.**

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| Date:  May 28, 2008 |   | /s/ Stanislaw R.  Burzynski           |
|--------------------------|--------|---------------------------------------|
|                     |   | Stanislaw R.  Burzynski,              |
|                     |   | President,  Secretary, Treasurer, and |
|                     |   | Chairman of the  Board of Directors   |
|                     |   | (Chief Executive  Officer and         |
|                     |   | Principal  Financial Officer)         |

 

 

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