Exhibit






Exhibit 10.1
	
																			
	 	AMENDMENT OF SOLICITATION/MODIFICATION OF CONTRACT
	1.  CONTRACT ID CODE
	PAGE OF PAGES

	 	1
	1

	 	2.  AMENDMENT/MODIFICATION NO.
0021
	3.  EFFECTIVE DATE
See Block 16C
	4.  REQUISITION/PURCHASE REQ. NO.
	5.  PROJECT NO. (If applicable)

	 	6.  ISSUED BY                                                     CODE
	ASPR-BARDA
	7.  ADMINISTERED BY (If other than Item 6)                    CODE
	ASPR-BARDA

	 	

ASPR-BARDA
200 Independence Ave., S.W.
Room 640-G
Washington DC  20201
	

ASPR-BARDA
200 Independence Ave., S.W.
Room 638-G
Washington DC  20201

	 	8.  NAME AND ADDRESS OF CONTRACTOR (No., street, county, State and ZIP Code)
	(X)
	9A.  AMENDMENT OF SOLICITATION NO.

	 	ACHAOGEN, INC. 1361331
ACHAOGEN, INC.            7000 SHORELINE
7000 SHORELINE CT STE 371
SOUTH SAN FRANCISCO CA  940801957
	 

	 	9B.  DATED (SEE ITEM 11)

	 
	 	X
	10A.  MODIFICATION OF CONTRACT/ORDER NO.
HHSO100201000046C

	 	CODE     1361331
	FACILITY CODE
	10B.  DATED (SEE ITEM 13)
09/01/2010

	 	11.  THIS ITEM ONLY APPLIES TO AMENDMENTS OF SOLICITATIONS

	 	o 
	The above numbered solicitation is amended as set forth in Item 14.  The hour and date specified for receipt of Offers
	o is extended
	o is not extended

	 	 
	Offers must acknowledge receipt of this amendment prior to the hour and date specified in the solicitation or as amended, by one of the following methods:  (a) By completing
Items 8 and 15, and returning _______________ copies of the amendment; (b) By acknowledging receipt of this amendment on each copy of the offer submitted; or (c) By
separate letter or telegram which includes a reference to the solicitation and amendment numbers.  FAILURE OF YOUR ACKNOWLEDGEMENT TO BE RECEIVED AT
THE PLACE DESIGNATED FOR THE RECEIPT OF OFFERS PRIOR TO THE HOUR AND DATE SPECIFIED MAY RESULT IN REJECTION OF YOUR OFFER.  If by
virtue of this amendment you desire to change an offer already submitted, such change may be made by telegram or letter, provided each telegram or letter makes
reference to the solicitation and this amendment, and is received prior to the opening hour and date specified.

	 	12.  ACCOUNTING AND APPROPRIATION DATA (If required)
See Schedule

	 	13.  THIS ITEM ONLY APPLIES TO MODIFICATION OF CONTRACTS/ORDERS.  IT MODIFIES THE CONTRACT/ORDER NO. AS DESCRIBED IN ITEM 14.

	 	CHECK ONE
	A.    THIS CHANGE ORDER IS ISSUED PURSUANT TO:  (Specify authority) THE CHANGES SET FORTH IN ITEM 14 ARE MADE IN THE CONTRACT 
ORDER NO. IN ITEM 10A.

	 	 

	 	 
	B.    THE ABOVE NUMBERED CONTRACT/ORDER IS MODIFIED TO REFLECT THE ADMINISTRATIVE CHANGES (such as changes in paying office, 
appropriation date. etc.) SET FORTH IN ITEM 14, PURSUANT TO THE AUTHORITY OF FAR 43.103(b).

	 	 
	C.    THIS SUPPLEMENTAL AGREEMENT IS ENTERED INTO PURSUANT TO AUTHORITY OF:

	 	X
	D.    OTHER (Specify type of modification and authority)


Bilateral:  Mutual Agreement of the Parties.

	 	E.  IMPORTANT:
	Contractor
	o is not
	ý   is required to sign this document and return      2      copies to the issuing office.

	 	14.  DESCRIPTION OF AMENDMENT/MODIFICATION (Organized by UCF section headings, including solicitation/contract subject matter where feasible.)
Tax ID Number:  68-0533693
DUNS Number:  167293153
A. The purpose of this bilateral no cost modification is to incorporate the following change into the contract:
1.     Under Article G.3., Key Personnel, the BARDA Liaison is hereby changed from [***] to [***].
B.    This is a bi-lateral, no cost modification. The total amount and all other terms and
conditions of contract number HHSO100201000046C remain unchanged.
Period of Performance: 09/19/2010 to 11/15/2017

	 	Except as provided herein, all terms and conditions of the document referenced in Item 9A or 10A, as heretofore changed, remains unchanged and in full force and effect.

	 	15A.  NAME AND TITLE OF SIGNER (Type or print)
Michael Conway, Director of Finance
	16A.  NAME AND TITLE OF CONTRACTING OFFICER (Type or print)
THOMAS P. HASTINGS

	 	15B.  CONTRACTOR/OFFEROR
/s/ Michael Conway                       
(Signature of person authorized to sign)
	15C.  DATE SIGNED
7/7/15
	16B.  UNITED STATES OF AMERICA
/s/Thomas P. Hastings              
(Signature of Contracting Officer)
	16C.  DATE SIGNED


 7/8/15

	 	

NSN 7540-01-152-8070
Previous edition unusable/
	 
	STANDARD FORM 30 (REV. 10-83)
Prescribed by GSA
FAR (48 CFR) 53.243











[***]    Certain information in this document has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been requested with respect to the omitted portions.