Exhibit 10.3

 

Confidential Treatment Requested Under 17 C.F.R. §§ 200.80(b)(4) and 240-24b-2

 

WORK ORDER NO. 12

 

THIS WORK ORDER NO. 12 is by and between RADIUS HEALTH, INC. (“RADIUS”) and LONZA Sales Ltd, a Swiss company having an address at Muenchensteinerstrasse 38, CH-4002 Basel, Switzerland (together with its Affiliates, “Manufacturer”), and upon execution will be incorporated into the Development and Manufacturing Services Agreement between RADIUS and Manufacturer dated October 16, 2007 (the “Agreement”). Capitalized terms in this Work Order will have the same meanings as set forth in the Agreement.

 

RADIUS hereby engages Manufacturer to provide Services, as follows:

 

1.                                      API/Drug Substance and Product.

 

BA058

 

Peptide Sequence:  H-Ala-Val-Ser-Glu-His-Gln-Leu-Leu-His-Asp-Lys-Gly-Lys-Ser-Ile-Gln-Asp-Leu-Arg-Arg-Arg-Glu-Leu-Leu-Glu-Lys-Leu-Leu-Aib-Lys-Leu-His-Thr-Ala-NH2

 

2.                                      Services.  Manufacturer will render to RADIUS the following Services:

 

Activity 1:

 

	
·
    	
Report on development of analytical   methods FG2/TG2:
    	
Price : [*]€
    


 

Activity 2:

 

	
·
    	
Update of DP CoA with additional   specifications :
    	
Price: [*]€
    


 

Activity 3:

 

	
·
    	
Test of Phenol impact on API content by   FG2
    	
Price: [*]€
    


 

Activity 4:

 

	
·
    	
Manufacturing of a new reference standard   starting from
    	
 
    
	
 
    	
11.8g of lot 7ALI   (VAL1) – aliquots of 100mg (100 to 118 vials)
    	
Price: [*]€
    


 

Radius shall place purchase orders with Manufacturer in accordance with Work Order 12 and shall not be permitted to terminate the Services covered by such purchase orders.

 

3.                                      Facilities.  The Services described above will be rendered at the Facility unless another facility of Manufacturer is indicated below:

 

N/A

 

4.                                      RADIUS Materials.  RADIUS will provide to Manufacturer the following materials to be used by Manufacturer to perform the Services:

 

None

 

5.                                      RADIUS Equipment.

 

None

 











 

Confidential Treatment Requested Under 17 C.F.R. §§ 200.80(b)(4) and 240-24b-2

 

6.                                      Manufacturer Representative.

 

Richard W. Coombs,, Sales Manager, Lonza

 

7.                                      RADIUS Representative.

 

David Hanley, Executive Director, Technical Operations

 

8.                          Compensation.

 

Radius will be invoiced 100% upon execution of this Work Order [*]€.

 

The total compensation due Manufacturer for Services under this Work Order is not expected to exceed [*]€

 

9.                          General: RADIUS and Manufacturer must agree in advance of either party making any change in the compensation due hereunder. Manufacturer will invoice RADIUS to the attention of David Hanley, for Services rendered under this Work Order.  Manufacturer will invoice RADIUS for all amounts due under this Work Order.  All undisputed payments will be made by RADIUS within thirty (30) days of receipt of invoice.

 

All other terms and conditions of the Agreement will apply to this Work Order.

 

WORK ORDER AGREED TO AND ACCEPTED BY:

 

	
RADIUS HEALTH, INC.
    	
LONZA SALES LTD
    
	
 
    	
 
    
	
 
    	
 
    
	
By 
    	
/s/ Gregory C. Williams
    	
 
    	
By 
    	
/s/ Fabrice Gachot
    
	
 
    	
 
    	
 
    	
 
    	
 
    
	
 
    	
 
    	
 
    	
 
    	
 
    
	
Print Name 
    	
Gregory C. Williams
    	
 
    	
Print Name 
    	
Fabrice Gachot
    
	
Title 
    	
Chief Development   Officer
    	
 
    	
Title 
    	
Director / Key Account   Management
    
	
Date 
    	
13 August 2015
    	
 
    	
Date 
    	
24 Aug. 2015
    
	
 
    	
 
    
	
 
    	
 
    
	
 
    	
By 
    	
/s/ Nadia Zieger
    
	
 
    	
Print Name 
    	
Nadia Zieger
    
	
 
    	
Title 
    	
Senior Legal Counsel
    
	
 
    	
Date 
    	
24 Aug 2015
    
	
 
    	
 
    
	
 
    	
 
    
	
 
    	
Approve by LONZA Legal   Dept.
    
	
 
    	
 
    
	
 
    	
/s/ BGL