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Summary Minutes of the

U.S. Environmental Protection Agency (EPA)

Clean Air Scientific Advisory Committee (CASAC)

Lead Review Panel

Public Teleconference

May 5, 2011

Date and Time: Tuesday, May 5, 2011, 1:00 PM – 5:00 PM ET

Location: Teleconference Only

Purpose: The purpose of the teleconference was to provide consultative advice on EPA's 

Draft Integrated Review Plan for the National Ambient Air Quality Standards 

for Lead (Draft IRP).

Participants: CASAC Lead Panel

Dr. H. Christopher Frey, Chair

(for full roster, see Attachment A)

Mr. George Allen

Dr. Herbert Allen

Dr. Richard Canfield

Dr. Deborah Cory-Slechta

Dr. Cliff Davidson

Dr. Philip Goodrum

Dr. Chris Johnson

Dr. Susan Korrick

Dr. Michael Kosnett

Dr. Roman Lanno

Mr. Richard Poirot

Dr. Joel Pounds

Dr. William Stubblefield

Dr. Ian von Lindern

Dr. Gail Wasserman

Dr. Michael Weitzman

Mr. Aaron Yeow, Designated Federal Officer (DFO)

Dr. John Vandenberg, EPA National Center for Environmental Assessment (NCEA)

Dr. Ellen Kirrane, EPA NCEA

Dr. Deirdre Murphy, EPA Office of Air Quality and Planning Standards 

Other Attendees (See Attachment B)
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Thursday, May 5, 2011

Opening Remarks

Mr. Aaron Yeow, the DFO for the CASAC Lead Review Panel, opened the meeting. He noted 

that as required under the Federal Advisory Committee Act (FACA), the Panel’s deliberations 

are held in public with advanced notice given in the Federal Register1, and the meeting minutes 

will be made publicly available after the meeting. He noted that the Panel received one request 

from the public to present oral comments, and received one set of written comments from the 

public. He also noted that the Panel members are all in compliance with federal ethics 

regulations and conflict-of-interest laws that pertain to them. He then turned the meeting over to 

Dr. Chris Frey, Chair of the CASAC Lead Review Panel.

Dr. Frey welcomed everyone, introduced the Panel, described what a consultation was, and 

described the review schedule. He indicated that the purpose of the meeting was to provide 

consultative advice on EPA's Draft Integrated Review Plan for the National Ambient Air Quality 

Standards for Lead (Draft IRP)2

. He reviewed the Agenda for the meeting3, and introduced Dr. 

John Vandenberg, from EPA’s National Center for Environmental Assessment (NCEA) for his

presentation.

EPA Presentation

Dr. John Vandenberg, EPA NCEA, made a presentation4 to the Panel. He introduced the Lead 

National Ambient Air Quality Standards (NAAQS) team, consisting of staff from EPA’s NCEA 

and OAQPS and provided an overview of the NAAQS review process and the schedule for the 

current Lead NAAQS review. He then turned it over to Dr. Deirdre Murphy for the remainder of 

the presentation.

Dr. Deirdre Murphy, OAQPS, presented the Panel with two overarching questions for the Lead 

NAAQS review: in light of newly available information, is the current primary standard 

requisite to protect public health with an adequate margin of safety and in light of newly 

available information, is the current secondary standard protective of public welfare from

any known or anticipated adverse effects? She provided an overview of the science policy 

workshop held in May 2010 and gave an outline of the Draft IRP document.

Public Comment

Mr. Richard Watson, Richard Watson & Associates, Inc., registered to provide oral comments, 

but was not present on the call.

Chapter 3 - Key Policy-Relevant Issues

The Panel members generally believed that overall it was a good start. Most of the policyrelevant questions were identified. One member stated that EPA need to consider the effects of 

lead on reactive oxygen, whether it is a real effect, or just a measure of exposure. The member 

also stated that EPA should consider the Agency’s Metals Framework document and to include 
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more information about the chemistry of lead, bioavailability, and bioaccumulation. Another 

member indicated that one missing policy-relevant issue is cumulative risk, that lead may 

enhance other risk factors.

Chapter 4 - Science Assessment

The Panel was generally please with the chapter and believed that the plan was strong and 

complete. Several members commented that they would have like to see what the criteria for 

selection of studies were. One member indicated that examining critical loads was a promising 

way to look at ecosystems. Several members commented that other human health outcomes 

besides neurocogntive measures should be expanded upon in the document, particularly 

emerging outcomes such as behavioral outcomes. One member commented that focusing too 

much on early development may cause the missing out of other important time frames such as 

adolescence. 

Chapter 5 - Quantitative Risk and Exposure Assessment

One member commented that even though air is the indicator, the primary exposure route for 

lead is not inhalation. Several Panel members mentioned consideration of an incremental risk 

assessment approach. One member indicated that although chemistry matters, bioavailability 

matters as well. He applauded EPA for wanted to use existing approaches, but noted that some 

of those approaches are quite outdated. He noted that the Agency’s Metals Framework 

document should guide the risk assessment.

Chapter 6 - Ambient Air Monitoring

Several members criticized the TSP high-volume sampler. It was designed in the 1940s and if 

introduced as a new sampler today, it would not pass as a Federal Reference Method (FRM). 

The members encouraged EPA to consider what particle sizes they are after and develop or 

evaluate other sampling methods to capture those size cuts.

Dr. Frey discussed next steps and action items.

With the business concluded, the Designated Federal Officer adjourned the meeting at 4:00 PM 

ET.

Respectfully Submitted: Certified as Accurate:

/signed/ /signed/

Mr. Aaron Yeow Dr. H. Christopher Frey

Designated Federal Officer Chair

EPA SAB Staff Office CASAC Lead Review Panel
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NOTE AND DISCLAIMER: The minutes of this public meeting reflect diverse ideas and 

suggestions offered by Panel members during the course of deliberations within the meeting. Such 

ideas, suggestions and deliberations do not necessarily reflect consensus advice from the Panel 

members. The reader is cautioned to not rely on the minutes to represent final, approved, consensus 

advice and recommendations offered to the Agency. Such advice and recommendations may be 

found in the final advisories, commentaries, letters or reports prepared and transmitted to the EPA 

Administrator following the public meetings.
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Materials Cited

The following meeting materials are available on the CASAC website: 

http://www.epa.gov/casac, at the May 5, 2011 CASAC Lead Review Panel Meeting page:

 1 Federal Register Notice Announcing the Meeting

2 Integrated Review Plan for the National Ambient Air Quality Standards for Lead - External Review Draft (March 

2011)

3 Agenda for May 5, 2011 Public Meeting

4 Review of the National Ambient Air Quality Standards for Lead - Draft Integrated Review Plan
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ATTACHMENT A - ROSTER

U.S. Environmental Protection Agency

Clean Air Scientific Advisory Committee

CASAC Lead Review Panel (2010-2013)

CHAIR

Dr. H. Christopher Frey, Professor, Department of Civil, Construction and Environmental 

Engineering, College of Engineering, North Carolina State University, Raleigh, NC

MEMBERS

Mr. George A. Allen, Senior Scientist, Northeast States for Coordinated Air Use Management 

(NESCAUM), Boston, MA

Dr. Herbert Allen, Professor Emeritus, Department of Civil and Environmental Engineering, 

University of Delaware, Newark, DE

Dr. Richard Canfield, Senior Research Associate, Division of Nutritional Sciences, Cornell 

University, Ithaca, NY

Dr. Deborah Cory-Slechta, Professor, Department of Environmental Medicine, School of 

Medicine and Dentistry, University of Rochester, Rochester, NY

Dr. Cliff Davidson, Professor, Civil and Environmental Engineering, Syracuse University, 

Syracuse, NY

Dr. Philip E. Goodrum, Senior Project Manager, Environmental Resources Management 

(ERM), Dewitt, NY

Dr. Sean Hays*, President, Summit Toxicology, Allenspark, CO

Dr. Philip Hopke, Bayard D. Clarkson Distinguished Professor, Department of Chemical and 

Biomolecular Engineering, Clarkson University, Potsdam, NY

Dr. Chris Johnson, Professor, Department of Civil and Environmental Engineering , Syracuse 

University, Syracuse, NY

Dr. Susan Korrick, Assistant Professor of Medicine , Department of Medicine, Brigham and 

Women's Hospital, Channing Laboratory, Harvard Medical School, Boston, MA
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Dr. Michael Kosnett, Associate Clinical Professor, Division of Clinical Pharmacology and 

Toxicology, Department of Medicine, University of Colorado Health Sciences Center, Denver, 

CO

Dr. Roman Lanno, Associate Professor and Associate Chair, Department of Evolution, 

Ecology, and Organismal Biology, Ohio State University, Columbus, OH

Mr. Richard L. Poirot, Environmental Analyst, Air Pollution Control Division, Department of 

Environmental Conservation, Vermont Agency of Natural Resources, Waterbury, VT

Dr. Joel Pounds, Scientist, Cell Biology & Biochemistry, Biological Sciences Division, Battelle 

- Pacific Northwest National Laboratory, Richland, WA

Dr. Michael Rabinowitz*, Geochemist, Clinical Instructor in Neurology, Harvard University, 

Newport, RI

Dr. William Stubblefield, Senior Research Professor, Department of Molecular and 

Environmental Toxicology, Oregon State University, Corvallis, OR

Dr. Ian von Lindern, President, TerraGraphics Environmental Engineering, Inc., Moscow, ID

Dr. Gail Wasserman, Professor of Clinical Psychology in Child Psychiatry, Division of Child 

and Adolescent Psychiatry, College of Physicians and Surgeons, Columbia University, New 

York, NY

Dr. Michael Weitzman, Professor, Pediatrics; Psychiatry, New York University School of 

Medicine, New York, NY

*Did not participate in this review.

SCIENCE ADVISORY BOARD STAFF

Mr. Aaron Yeow, Designated Federal Officer, U.S. Environmental Protection Agency, Science 

Advisory Board (1400R), 1200 Pennsylvania Avenue, NW, Washington, DC, Phone: 202-564-

2050, Fax: 202-565-2098, (yeow.aaron@epa.gov)
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ATTACHMENT B – Other Attendees

CASAC Lead Panel Public Teleconference

May 5, 2011

Name Affiliation

Bertrand, Charlotte EPA

Bowers, Terri Gradient

Bryant, Christopher Bergeson & Campbell, P.C.

Flynn, Thomas J. III SC Department of Health and Environmental Control

Gouze, Steve CalEPA Air Resources Board

Kurtz, Katharine US Navy

Ross, Mary EPA

Volpe, Rosalind International Lead Zinc Research Org

Wilson, Linda NYS Office of the Attorney General