UNITED STATES ENVIRONMENTAL PROTECTION AGENCY 

WASHINGTON D.C., 20460 

OFFICE OF 

PREVENTION, PESTICIDES AND 

TOXIC SUBSTANCES

 PC Code: 080818 

DP Barcodes: 356140, 367446 

 Date: March 11, 2010 

MEMORANDUM 

SUBJECT: Transmittal Memorandum for: Environmental Fate and Ecological Risk 

Assessment in Support of the Section 3 Registration of the New Chemical 

Indaziflam (BCS AA10717) 

TO: Erik Kraft, Chemical Review Manager 

 Jim Tompkins, Risk Manager 

 Registration Division (7505P) 

FROM: Reuben Baris, Physical Scientist 

 Alicia Korol, Biologist 

 Environmental Risk Branch IV 

 Environmental Fate and Effects Division (7507P) 

REVIEWED 

BY: Thomas M. Steeger, Ph.D., Senior Biologist 

 Marietta Echeverria, Risk Assessment Process Leader 

Environmental Risk Branch IV 

 Environmental Fate and Effects Division (7507P) 

APPROVED 

BY: Elizabeth Behl, Branch Chief 

 Environmental Risk Branch IV 

 Environmental Fate and Effects Division (7507P) 

 The Environmental Fate and Effects Division (EFED) has completed the environmental 

fate and ecological risk assessment in support of the Section 3 registration decision on the new 

herbicide indaziflam (BCS AA10717). The results of this screening-level risk assessment 

indicate that the proposed uses of indaziflam at a single maximum application rate of 0.125 lb 

a.i./acre and maximum annual application rate of 0.134 lb a.i./L pose risk to listed and nonlisted 

species of terrestrial plants and aquatic vascular plants; RQs for these taxa for each use pattern 

exceeded the listed and nonlisted species LOC. Based on an analysis of risk to terrestrial plants 

from spray drift, buffers of ~350 feet and buffers of ~550 feet for broadcast applications of 

indaziflam would reduce RQs below the nonlisted and listed species LOCs, respectively, for all 

Page 1 of 12
turf and food uses. These buffers would not be protective of all listed and nonlisted species for 

the other proposed broadcast uses of indaziflam, but they are expected to reduce the number of 

species ultimately affected. Proposed uses of indaziflam also pose risk to listed nonvascular 

plants, with RQs only slightly exceeding the LOC for home lawn and ornamental uses. Based on 

lack of data or inadequacy of data, chronic risk to estuarine/marine invertebrates and birds 

resulting from indaziflam use is presumed. Details regarding the environmental fate, ecological 

effects and ecological risks associated with the proposed uses of indaziflam can be found in the 

executive summary of the attached document. 

Data Gaps 

 The available environmental fate and transport data for indaziflam are considered 

complete and adequate for risk assessment purposes. The submitted toxicity studies for 

evaluation of environmental effects are considered adequate for risk assessment purposes, 

however the suite of data is incomplete with one identified data gap. An estuarine/marine 

invertebrate life cycle toxicity study, OPPTS 850.1350, was not submitted but is required since 

indaziflam was demonstrated to be “highly toxic” to estuarine/marine organisms, EC50 = 0.1-1 

mg/L. Given the proposed turf uses of indaziflam, it is reasonable to assume that indaziflam 

could move into an estuarine/marine environment. Chronic ecological risk to this taxon is 

unknown and thus risk is presumed. The remaining toxicity studies with their classifications are 

presented in Table 1, which identifies the status of ecological effects study requirements, and

Table 2, which identifies the status of environmental fate and transport study requirements. 

 

Uncertainties 

 An area of considerable uncertainty surrounds the potential ecological chronic risk to 

birds. Current data on Mallard duck were inadequate to derive a definitive NOAEC or make a 

definitive determination of risk. At the lowest levels tested from reproductive studies on Mallard 

duck, effects were observed on male body weight, female body weight, and food consumption. 

An additional avian reproduction study on Mallard duck (OPPTS 850.2300) would reduce 

uncertainty and may obviate the need to assume risk to this taxon. 

There is also considerable uncertainty associated with the modeled aquatic exposure 

resulting from hardscape and residential (home lawns and ornamental) uses. A number of 

assumptions were made in the modeling of these uses and may not represent actual use patterns. 

For example, the use on hardscapes and lawns may be a spot treatment and all lawns in a 

watershed may not be simultaneously treated. To the extent that actual use patterns differ from 

modeling assumptions, actual environmental concentrations could be lower. Proposed label 

language is ambiguous and can be misinterpreted leading to misapplications. For example, label 

instructions that require use only as a spot treatment in cracks and crevices of hardscapes 

(driveways, sidewalks, patios), as opposed to broadcast applications would reduce the potential 

aquatic exposure estimates. Further, adding label language that specifies the definition of 

hardscapes on the BCS AA10717 20WSP label would also reduce uncertainty in exposure 

estimates. 

Page 2 of 12
 Additionally, degradates of indaziflam, specifically fluoroethyldiaminotriazine, are much 

more mobile than the parent, and data show that they persist in the environment under aerobic 

and anaerobic conditions. Field studies indicate that degradates of indaziflam residues may leach 

to ground water; fluoroethyldiaminotriazine was detected at deeper depths in the field studies 

compared to the other degradates. A prospective ground water study (PGW) would help to 

characterize the magnitude and extent of the potential ground water contamination. 

Labeling Recommendations 

 The following recommendations are relevant to the Lawn 3FL formulation and the BCSAA10717 20WSP labels. 

• On all Lawn 3FL formulations, proposed labels state, “Use on established southern lawns 

only.” This label language is vague and ambiguous regarding the potential use sites. 

Specifying states that permit use of indaziflam will spatially reduce the potential 

exposure. 

• On the Lawn 3FL Herbicide Concentrate formulation (PART C: Ornamentals & 

Hardscapes), label language that specifies use only as a spot treatment in cracks and 

crevices of hardscapes (driveways, sidewalks, patios), as opposed to broadcast 

applications would reduce the potential aquatic exposure estimates. We recommend 

replacing existing text in the “where to use” box under the “quick facts”: 

Use only as a spot treatment in cracks and crevices of hardscapes such as patios, 

sidewalks, driveways, pathways, gravel areas, and along fence lines. Do not apply 

as broadcast application. 

• On the BCS AA10717 20WSP formulation: 

o In the Non-selective Non-Crop Uses section, label language that specifies use 

only as a spot treatment in cracks and crevices of hardscapes (driveways, 

sidewalks, patios), as opposed to broadcast applications, would reduce the 

potential aquatic exposure estimates. For example: 

 For long term control of annual weeds in non crop areas including patios, 

 walkways, and other hardscapes, use spot treatments of BCSAA10717 20 

 WSP Herbicide at 3.5-7.1 oz per A...For difficult-to-control weeds, more 

 extended control, use 7.1 oz of BCS-AA10717 20 WSP Herbicide per A. 

 Do not exceed 7.1 oz per A in a contiguous 12 months. 

o In the Non-selective Non-Crop Uses section, we recommend that reference to 

“other hardscapes” be removed, or explicitly defined.

Page 3 of 12
o Label language on spray drift management for broadcast ground applications 

would reduce potential exposure to terrestrial and aquatic plants from off-field 

spray drift deposition. For consistency, we recommend inserting the identical 

language as provided for Esplanade 200 SC, Indaziflam 200 SC, and Indaziflam 

500 SC formulations. 

Table 1. Ecological Effects Studies for Indaziflam 

Guideline MRID Study Title Issues Study 

Classification

850.1010 47443226 Indaziflam - Acute Toxicity to Daphnia magna 

in a 48 Hour Static Test 

Test media was not 

centrifuged to 

determine dissolved 

test substance 

concentration. 

Supplemental 

850.1035 47443227 Indaziflam Technical - 96-hr Static Acute 

Toxicity Test with the Saltwater Mysid 

(Americamysis bahia) 

None Acceptable 

850.1025 47443228 Indaziflam Technical - 96-hr Shell Deposition 

Test with the Eastern Oyster (Crassostrea 

virginica) under Flow-through Conditions 

Test media was not 

centrifuged to 

determine dissolved 

test substance 

concentration. 

Supplemental 

850.1075 47443229 Indaziflam Technical - Acute Toxicity Study on 

the Fathead Minnow (Pimephales promelas) in 

a Static System over 96 hours 

Test media was not 

centrifuged to 

determine dissolved 

test substance 

concentration. 

Supplemental 

850.1075 47443230 Fluoroethyldiaminotriazine - Acute Toxicity 

Study on the Fathead Minnow (Pimephales 

promelas) in a Static System Over 96 Hours 

None Acceptable 

850.1075 47443231 Indaziflam-carboxylic Acid - Acute Toxicity 

Study on the Fathead Minnow (Pimephales 

promelas) in a Static System Over 96 Hours 

None Acceptable 

850.1075 47443232 Indaziflam Technical – 96-h Acute Toxicity 

Study on Sheepshead Minnow (Cyprinodon 

variegates) under Static Conditions 

Test media was not 

centrifuged to 

determine dissolved 

test substance 

concentration. 

Supplemental 

850.1075 47443233 Indaziflam Technical - A 96-Hour Static Acute 

Toxicity Test with the Bluegill Sunfish 

(Lepomis macrochirus) 

Test media was not 

centrifuged to 

determine dissolved 

test substance 

concentration. 

Supplemental 

850.1075 47443234 Indaziflam Technical - Acute Toxicity Study on 

the Rainbow Trout (Oncorhynchus mykiss) in a 

Static System Over 96 Hours 

Test media was not 

centrifuged to 

determine dissolved 

test substance 

concentration. 

Supplemental 

Page 4 of 12
850.1300 47443235 Indaziflam Technical – 21-day Chronic 

Toxicity to Daphnia magna under Staticrenewal Conditions 

Effects to offspring 

were not measured & 

test media was not 

centrifuged to 

determine dissolved 

test substance 

concentration. 

Supplemental 

850.1400 47443236 Indaziflam Technical – 35-day Early Life Stage 

Toxicity test on the Fathead Minnow 

(Pimephales promelas) under Flow-through 

Conditions 

Statistically 

significant difference 

between negative and 

solvent controls for 

mean dry weight & 

test media was not 

centrifuged to 

determine dissolved 

test substance 

concentration. 

Supplemental 

850.1735 47443238 Indaziflam Technical – 10-day Acute Whole 

Sediment Toxicity Study with Freshwater 

Midge (Chironomus tetans) 

Overlying water 

concentrations were 

not centrifugedto 

determine dissolved 

test substance 

concentration 

Supplemental 

850.1740 47443239 Indaziflam Technical – 10-day Acute Whole 

Sediment Test with Marine Amphipod 

Leptocheirus plumulosus under Static 

Conditions 

Overlying water 

concentrations were 

not centrifuged to 

determine dissolved 

test substance 

concentration 

Supplemental 

850.2100 47443240 Indaziflam Technical – Acute Toxicity in the 

Bobwhite Quail (Colinus virginiamus) After 

Single Oral Administration (LD50) 

None Acceptable 

850.2200 47443241 Indaziflam Technical – Subacute Dietary LC50 

with Northern Bobwhite Quail (Colinus 

virginiamus) 

None Acceptable 

850.2200 47443242 Indaziflam Technical – Subacute Dietary LC50 

with Mallard Duck (Anas platyrhnchos) 

None Acceptable 

850.2300 47443243 Indaziflam Technical – One Generation 

Reproduction Study on the Bobwhite Quail 

(Colinus virginiamus) 

by Administration in the Diet 

None Acceptable 

850.2300 47443244 Indaziflam Technical – One Generation 

Reproduction Study on the Mallard Duck (Anas 

platyrhnchos) by Administration in the Diet 

Non-definitive 

NOAEC 

Supplemental 

850.3020 47443245 Indaziflam Technical - Acute Contact Toxicity 

Study with the Honey Bee 

None Acceptable 

Page 5 of 12
850.4225 47443246 BCS-AA10717 20WSP - Toxicity Test to 

Determine the Effects of the Test Substance on 

Seedling Emergence of Terrestrial Plant Species

None Acceptable 

850.4225 47443247 Indaziflam 500 SC - Toxicity Test to Determine 

the Effects of the Test Substance on Seedling 

Emergence of Terrestrial Plant Species 

None Acceptable 

850.4250 47443248 BCS-AA10717 20WSP - Toxicity Test to 

Determine the Effects of the Test Substance on 

Vegetative Vigor of Terrestrial Plant Species 

An associated 

NOAEC/EC05 could 

not be determined for 

the lowest EC50

Supplemental 

850.4250 47443249 BCS-AA10717 20WSP - Toxicity Test to 

Determine the Effects of the Test Substance on 

Vegetative Vigor of Terrestrial Plant Species 

Study failed to define 

a NOAEC or EC05 

corresponding to the 

lowest EC25 for 

dicots. 

Supplemental 

850.4400 47443250 Indaziflam Technical – Tier II 7-day Aquatic 

Plant Test on the Growth of Lemna gibba 

None Acceptable 

850.4400 47443251 Triazine-Indanone – Tier II 7-Day Toxicity Test 

with Duckweed (Lemna gibba G3) 

None Acceptable 

850.4400 47443252 Fluoroethyldiaminotriazine – Tier II 7-Day 

Toxicity Test with Duckweed (Lemna gibba 

G3) 

Failed to determine 

most sensitive 

endpoint 

Supplemental 

850.4400 47443253 Indaziflam-carboxylic Acid – Tier II 7-Day 

Toxicity Test with Duckweed (Lemna gibba 

G3) 

None Acceptable 

850.4400 47443254 Indaziflam-hydroxyethyl – Tier II 7-Day 

Toxicity Test with Duckweed (Lemna gibba 

G3) 

None Acceptable 

850.4400 47443255 Indaziflam-olefine – Tier II 7-Day Toxicity 

Test with Duckweed (Lemna gibba G3) 

None Acceptable 

Nonguideline 47443256 Indaziflam Technical – Growth Inhibition Test 

in a Water/Sediment System using Spiked 

Water with Duckweed (Lemna gibba) under 

Static Conditions 

Non-guideline Supplemental 

850.4450 47443257 BCS-AA10717 SC 500 G/L – Tier III 

Ecological Effects Test in Outdoor 

Experimental Ponds Inhabited with 

Macrophytes 

Multiple deviations 

from guideline; was 

submitted as 

supplemental data 

Supplemental 

Nonguideline 47443258 Indaziflam Technical – Non-guideline 

Screening Test on Effects to Aquatic 

Macrophytes in Outdoor Simulated Ponds 

Non-guideline Supplemental 

Nonguideline 47443259 Analysis of AE 1170437 concentrations in 

sediment samples of ALTERRA Study No. 

ALT.SC.2007.1 

Non-guideline Extraneous Data -

No study 

classification 

given. 

Nonguideline 47443260 Analysis of AE 1170437 concentrations in 

water samples of ALTERRA Study No. 

ALT.SC.2007.1 

Non-guideline Extraneous Data -

No study 

classification 

given. 

Page 6 of 12
850.5400 47443261 Indaziflam Technical – 96-hr Test on the 

Growth of the Green Alga Pseudokirchneriella 

subcapitata 

None Acceptable 

850.5400 47443262 Fluoroethyldiaminotriazine - 72-Hour Toxicity 

Test with the Freshwater Green Alga 

(Pseudokirchneriella subcapitata) 

Study length 72 hours Supplemental 

850.5400 47443263 Indaziflam - carboxylic Acid - 72-Hour 

Toxicity Test with the Freshwater Green Alga 

(Pseudokirchneriella subcapitata) 

Study length 72 hours Supplemental 

850.5400 47443264 Indaziflam - hydroxyethyl - 72-Hour Toxicity 

Test with the Freshwater Green Alga 

(Pseudokirchneriella subcapitata) 

Study length 72 hours Supplemental 

850.5400 47443265 Indaziflam - olefine - 72-Hour Toxicity Test 

with the Freshwater Green Alga 

(Pseudokirchneriella subcapitata) 

Study length 72 hours Supplemental 

850.5400 47443266 Indaziflam Technical - 96-Hour Toxicity Test 

with the Freshwater Alga (Navicula pelliculosa)

Test media was not 

centrifuged to 

determine dissolved 

test substance 

concentration. 

Supplemental 

850.5400 47443267 Indaziflam Technical - 96-Hour Toxicity Test 

with the Saltwater Diatom (Skeletonema 

costatum) 

None Acceptable 

850.5400 47443268 Indaziflam Technical - 96-Hour Toxicity Test 

with the Freshwater Cyanobacteria (Anabaena 

flos-aquae) 

Test media was not 

centrifuged to 

determine dissolved 

test substance 

concentration. 

Supplemental 

Nonguideline 

47443269 Indaziflam Technical – Acute Toxicity Study 

on Earthworms (Eisenia fetida andrei) 

A 14-day test instead 

of a 28-day test was 

conducted. 

Supplemental 

850.1010 47743303 Indaziflam 500 SC – Acute toxicity to Daphnia 

magna in a 48 Hour Static Test 

Test media was not 

centrifuged to 

determine dissolved 

test substance 

concentration. 

Supplemental 

850.1010 47743304 Indaziflam 200 SC – Acute toxicity to Daphnia 

magna in a 48 Hour Static Test 

Test media was not 

centrifuged to 

determine dissolved 

test substance 

concentration. 

Supplemental 

850.1075 47743305 Indaziflam 500 SC – Acute toxicity to Bluegill 

Sunfish (Lepomis macrochirus) over 96 hrs 

Test media was not 

centrifuged to 

determine dissolved 

test substance 

concentration. 

Supplemental 

850.2100 47743306 Indaziflam Technical – An Acute Oral Toxicity 

Study with the Zebra Finch 

None Acceptable 

Page 7 of 12
850.3020 47743307 Indaziflam 500 SC – Acute Toxicity Study to 

the honeybee (Apic melifera L.) under 

laboratory conditions 

None Acceptable 

850.4400 47743308 Indaziflam 500 SC – Tier II 7-day Aquatic 

Plant Test on the Growth of Lemna gibba 

None Acceptable 

850.5400 47743309 Indaziflam Technical - 96-hr Test on the 

Growth of the Green Alga Pseudokirchneriella 

subcapitata 

None Acceteptable 

850.5400 47743310 Indaziflam 500 SC - 72-Hour Toxicity Test 

with the Freshwater Green Alga 

(Pseudokirchneriella subcapitata) 

Study length 72 hours Supplemental 

850.5400 47743311 Indaziflam 200 SC - 72-Hour Toxicity Test 

with the Freshwater Green Alga 

(Pseudokirchneriella subcapitata) 

Study length 72 hours; 

light intensities two 

times recommended 

levels 

Supplemental 

Nonguideline 47743312 Fluoroethyldiaminotriazine - Acute Toxicity 

Study on Earthworms (Eisenia fetida andrei) 

A 14-day test instead 

of a 28-day test was 

conducted 

Supplemental 

Nonguideline 47743313 Triazine-indanone - Acute Toxicity Study on 

Earthworms (Eisenia fetida andrei) 

A 14-day test instead 

of a 28-day test was 

conducted 

Supplemental 

Nonguideline 47743314 Indaziflam – carboxylic acid - Acute Toxicity 

Study on Earthworms (Eisenia fetida andrei) 

A 14-day test instead 

of a 28-day test was 

conducted 

Supplemental 

Nonguideline 47743315 Indaziflam 500 SC - Acute Toxicity Study on 

Earthworms (Eisenia fetida andrei) 

A 14-day test instead 

of a 28-day test was 

conducted 

Supplemental 

860.6200 47743316 Indaziflam 500 SC – Survival, Growth, and 

Reproduction toxicity test on Earthworms 

(Eisenia fetida andrei) 

Did not test 

concentrations to 

guideline limit to 

dervive an LC50

Supplemental 

Page 8 of 12
Table 2. Environmental Fate Studies for Indaziflam 

Guideline Study Title MRID Classification Comments 

Are data 

adequate for 

Risk 

Assessment? 

Current 

Additional Data 

Need 

835.2120 Hydrolysis 47443207 Acceptable No significant issues affecting the 

acceptability of the study were noted. Yes None 

835.2240 Photodegradation 

in Water 47443208 Supplemental 

Study duration not sufficient. 

Concentrations of the 2 major 

transformation products were still 

increasing at the study termination, 

precluding the determination of the 

patterns of formation and decline for 

each. 

Yes None 

835.2410 Photodegradation 

on Soil 47443209 Supplemental 

Study duration not sufficient. 

There was a decline in the dark controls

(11%), material balances are 

acceptable. No explainable reason for 

decline in dark controls (e.g., stable to 

hydrolysis) 

Yes None 

47443210 Supplemental 

Application rate was 4x the maximum 

proposed application rate to achieve 

appropriate sensitivity. Kinetics may 

not be accurately represented at the 

higher application mass. 

Overall recoveries of C14 residues 

from decreased during the study 

duration. 

Authors did not demonstrate that 

volatile trapping method was efficient 

at trapping high concentrations of 

volatile gases (e.g., CO2) 

Yes None 

47443211 Supplemental 

Application rate was 4x the maximum 

proposed application rate to achieve 

appropriate sensitivity. Kinetics may 

not be accurately represented at the 

higher application mass. 

In the California sandy loam, 

increasing % of AR for diaminotriazine 

was observed at the termination of the 

study precluding the determination of 

the patterns of formation and decline. 

Yes None. 

835.4100 Aerobic Soil 

Metabolism 

47443212 Supplemental 

Study duration not sufficient. This may 

not be sufficient to accurately establish 

the pattern of decline of the major 

transformation products. 

Replicates were not collected for three 

of the four soils tested, except for time 

0. 

Moisture content was higher than 

recommended in study guidelines (55% 

of max holding capacity vs 75% of 1/3 

bar soil moisture content) 

Yes None 

Page 9 of 12
Are data Current adequate for Guideline Study Title MRID Classification Comments Additional Data Risk Need Assessment? 

47443213 Supplemental 

Study duration not sufficient. This may 

not be sufficient to accurately establish 

the pattern of decline of the major 

transformation products. 

Replicates were not collected for three 

of the four soils tested, except for time 

0. 

Moisture content was higher than 

recommended in study guideline (55% 

of max holding capacity vs 75% of 1/3 

bar soil moisture content) 

Yes None 

47443214 Supplemental 

Study was conducted using 

diaminotraizine (a degradate) as the 

starting material 

Study duration not sufficient. This may 

not be sufficient to accurately establish 

the pattern of decline of the major 

transformation products. 

Moisture content was higher than 

recommended in study guideline (55% 

of max holding capacity vs 75% of 1/3 

bar) 

Yes None 

47443215 Supplemental 

A comparison of the behavior of the 

two active isomers. Samples were 

analyzed only for the parent 

compounds. 

This study does not provide 

quantitative data for the risk 

assessment, it shows the behavior of 

the two active isomers (diastereomers) 

of indaziflam (BCS AA10717). 

Used only for 

qualitative 

purposes. 

None 

835.4200 Anaerobic Soil 

Metabolism 47443216 Acceptable 

Moisture content during the aerobic 

phase was higher than recommended in 

study guidelines (55% of max holding 

capacity vs 75% of 1/3 bar) 

Yes None 

835.4300 Aerobic Aquatic 

Metabolism 47443217 Supplemental 

Study duration not sufficient. Duration 

not be sufficient to accurately establish 

the pattern of decline of the major 

transformation products. 

Yes None 

47443218 Acceptable Study conducted on Indane labeled 

compound. Yes None 

835.4400 

Anaerobic 

Aquatic 

Metabolism 47443219 Acceptable Study conducted on Triazine labeled 

compound. Yes None 

47443203 Acceptable No significant issues affecting the 

acceptability of the study were noted. 

835.1230 Yes None Mobility - 

Adsorption / 

Desorption 

47443204 Supplemental 

The test compound was triazineindanone a transformation product of 

AE 1170437. 

Yes None 

Page 10 of 12
Are data Current adequate for Guideline Study Title MRID Classification Comments Additional Data Risk Need Assessment? 

47443205 Supplemental 

The test compound was diaminotriazine

a transformation product of AE 

1170437. 

Yes None 

47443206 Supplemental 

The test compound was AE 1170437-

carboxylic acid a transformation 

product of AE 1170437. 

Yes None 

47443220 Supplemental 

Study conducted on CA Porterville 

sandy loam cropped with turf. 

Storage stability study showed slow 

degradation of degradate over the 

period of frozen storage. 

Yes None 

47443221 Supplemental 

Study conducted on FL Monticello 

loamy sand cropped with turf. 

Storage stability study showed slow 

degradation of degradate over the 

period of frozen storage. 

Yes None 

47443222 Supplemental 

Study conducted on NC Wayne County 

loamy sand cropped with turf. 

Storage stability study showed slow 

degradation of degradate over the 

period of frozen storage. 

Yes None 

47443223 Supplemental 

Study conducted on CA Porterville 

sandy loam, bare soil. 

Storage stability study showed slow 

degradation of degradate over the 

period of frozen storage. 

Yes None 

47443224 Supplemental 

Study conducted on FL Jefferson 

County sand/loamy sand, bare soil. 

Storage stability study showed slow 

degradation of degradate over the 

period of frozen storage. 

Yes None 

47443225 Supplemental 

Study conducted on NC Wayne County 

loamy sand, bare soil. 

Storage stability study showed slow 

degradation of degradate over the 

period of frozen storage. 

Yes None 

835.6100 Terrestrial Field 

Dissipation 

47743301 Supplemental 

Study conducted on Quincy loamy 

sand, bare soil, in Ephrata, Washington.

Storage stability study showed slow 

degradation of degradate over the 

period of frozen storage. 

Yes None 

Page 11 of 12
Are data Current adequate for Guideline Study Title MRID Classification Comments Additional Data Risk Need Assessment? 

47743302 Supplemental 

Study was conducted on Oakville 

loamy sand, bare soil, in North Rose, 

New York. 

Storage stability study showed slow 

degradation of degradate over the 

period of frozen storage. 

Yes None 

850.1730 Fish 

Accumulation 47443237 Acceptable No significant issues affecting the 

acceptability of the study were noted. Yes None 

47443279 Supplemental 

Samples fortified with olefin degraded 

slowly, (corrected mean recoveries 65-

88% following 427-433 days). 

Samples were not stored for a sufficient 

duration. 

N/A None 

860.1380 Storage stability 

47743328 Supplemental 

Study upgrades MRID 47443279; 

conducted for sufficient duration. 

Samples fortified with olefin degraded 

slowly, mean corrected recoveries 

ranging from 65 to 88% following 427 

to 433 days and from 47 to 67% 

following 732 to 736 days of storage 

N/A None 

Non-guideline 

Supplemental 

Information on 

Foreign Soils 

47793401 Supplemental 

Comparison of foreign (German) soils 

to location and soil taxonomy of US 

soil series. 

Yes None 

Page 12 of 12