23832 Federal Register / Vol. 72, No. 83 / Tuesday, May 1, 2007 / Notices 

Federal Register notice. Following the 

SACATM meeting, summary minutes 

will be prepared and available on NTP 

Web site or upon request. 

Preliminary Agenda 

Scientific Advisory Committee on 

Alternative Toxicological Methods 

June 12, 2007 

Marriott Bethesda North Hotel & 

Conference Center, 5701 Marinelli Road, 

Bethesda, Maryland 20852 

8:30 a.m. 

<bullet≤ Call to Order and 

Introductions 

<bullet≤ NICEATM–ICCVAM Update <bullet≤ Draft NICEATM–ICCVAM 5- 

Year Plan 

[cir] Public Comment 

Noon LUNCH 

1 p.m. <bullet≤ ICCVAM Evaluation of In 

Vitro Pyrogenicity Test Methods [cir] Public Comment 

<bullet≤ Nominations to ICCVAM 

[cir] Public Comment 

<bullet≤ NTP High Throughput 

Screening Initiative [cir] Public Comment 

<bullet≤ Update from the European 

Center for the Evaluation of 

Alternative Methods 

<bullet≤ Update from the Japanese 

Center for the Validation of 

Alternative Methods 

<bullet≤ Other Business 

5 p.m. ADJOURN 

Request for Comments 

Public input is invited and time is setaside at the meeting for presentation of 

oral comments. Each organization is 

allowed one time slot per public 

comment period. At least 7 minutes will 

be allotted for each speaker, and if time 

permits, may be extended up to 10 

minutes at the discretion of the chair. 

Registration for oral comments will also 

be available on-site, although time 

allowed for presentation by on-site 

registrants may be less than for preregistered speakers and will be 

determined by the number of persons 

who register at the meeting. Persons registering to make oral 

comments are asked to do so through 

the online registration form (http:// 

ntp.niehs.nih.gov/go/7441) and to send 

a copy of their statement to Dr. Wolfe 

(see ADDRESSES above) by June 4 to 

enable review by SACATM and NIEHS/ 

NTP staff prior to the meeting. Written 

statements can supplement and may 

expand the oral presentation. If 

registering on-site and reading from 

written text, please bring 40 copies of 

the statement for distribution and to 

supplement the record. Written 

comments received in response to this 

notice will be posted on the NTP Web 

site. Persons submitting written 

comments should include their name, 

affiliation (if applicable), and 

sponsoring organization (if any) with 

the document. 

Background Information on SACATM 

SACATM was established in response 

to the ICCVAM Authorization Act [42 

U.S.C. 285l–3(d)] and is composed of 

scientists from the public and private 

sectors. SACATM advises ICCVAM, 

NICEATM, and the Director of the 

NIEHS and NTP regarding statutorily 

mandated duties of ICCVAM and 

activities of NICEATM. SACATM 

provides advice on priorities and 

activities related to the development, 

validation, scientific review, regulatory 

acceptance, implementation, and 

national and international 

harmonization of new, revised, and 

alternative toxicological test methods. 

Additional information about SACATM, 

including the charter, roster, and 

records of past meetings, can be found 

at http://ntp.niehs.nih.gov/go/167. 

Information about NICEATM and 

ICCVAM is available at http:// 

iccvam.niehs.nih.gov or by contacting 

the NICEATM Director, Dr. William 

Stokes (telephone: 919–541–2384 or email: niceatm@niehs.nih.gov). 

Dated: April 17, 2007. 

Samuel H. Wilson, 

Deputy Director, National Institute of 

Environmental Health Sciences and National 

Toxicology Program. 

[FR Doc. E7–8289 Filed 4–30–07; 8:45 am] 

BILLING CODE 4140–01–P 

DEPARTMENT OF HEALTH AND 

HUMAN SERVICES 

National Institute of Environmental 

Health Sciences (NIEHS); National 

Toxicology Program (NTP); NTP 

Interagency Center for the Evaluation 

of Alternative Toxicological Methods 

(NICEATM); Availability of Draft 

NICEATM–ICCVAM 5-Year Plan and 

Request for Public Comments; 

Announcement of a Town Meeting on 

the Draft NICEATM–ICCVAM 5-Year 

Plan 

AGENCY: National Institute of 

Environmental Health Sciences 

(NIEHS), National Institutes of Health 

(NIH). 

ACTION: Meeting announcement and 

request for comments. 

SUMMARY: The NIEHS and NICEATM 

request public comments that can be 

considered by NICEATM, the 

Interagency Coordinating Committee on 

the Validation of Alternative Methods 

(ICCVAM), and relevant program offices 

on the draft NICEATM–ICCVAM 5-Year 

Plan. The draft plan addresses: (a) 

Research, development, translation, and 

validation of new and revised nonanimal and other alternatives assays for 

integration of relevant and reliable 

methods into federal agency testing 

programs and (b) identification of areas 

of high priority for new and revised 

non-animal and alternative assays for 

the replacement, reduction, and 

refinement (less pain and distress) of 

animal tests. The draft plan will be 

available on or before May 7, 2007, at 

the NICEATM–ICCVAM 5-Year Plan 

Web site (http://iccvam.niehs.nih.gov/ 

docs/5yearplan.htm). Copies of the draft 

plan may also be obtained by contacting 

NICEATM (see ADDRESSES below). 

NICEATM and ICCVAM will hold a 

public Town Meeting at the National 

Institutes of Health, Bethesda, Maryland 

on June 11, 2007, beginning at 1 p.m. to 

adjournment (5 p.m.) to receive oral 

comments on the draft NICEATM– 

ICCVAM 5-Year Plan. 

DATES: The draft NICEATM–ICCVAM 5- 

Year Plan will be available by May 7, 

2007. Registration to attend the meeting 

and written comments on the draft 

NICEATM–ICCVAM 5-Year Plan should 

be received by June 7, 2007. The Town 

Meeting will be held June 11, 2007. 

ADDRESSES: The Town Meeting will be 

held at the William H. Natcher 

Conference Center, Room E, NIH, 9000 

Rockville Pike, Bethesda, Maryland. 

Persons needing special assistance, such 

as sign language interpretation or other 

reasonable accommodation in order to 

attend, should contact 919–541–2475 

voice, 919–541–4644 TTY (text 

telephone), through the Federal TTY 

Relay System at 800–877–8339, or send 

e-mail to niehsoeeo@niehs.nih.gov. 

Requests should be made at least 7 days 

in advance of the meeting. Written 

comments should be submitted 

preferably electronically at the 

NICEATM–ICCVAM 5-Year Plan Web 

site: http://iccvam.niehs.nih.gov/docs/ 

5yearplan.htm. Comments can also be 

submitted by e-mail to 

5yearplan@niehs.nih.gov. 

FOR FURTHER INFORMATION CONTACT: 

Other correspondence should be 

directed to Dr. William S. Stokes, 

NICEATM Director (NIH/NIEHS, P.O. 

Box 12233, MD EC–17, Research 

Triangle Park, NC 27709; telephone: 

919–541–2384, fax: 919–541–0947 or email: niceatm@niehs.nih.gov. Courier 

address: NICEATM, 79 T.W. Alexander 

Drive, Building 4401, Room 3128, 

Research Triangle Park, NC 27709). 


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Federal Register / Vol. 72, No. 83 / Tuesday, May 1, 2007 / Notices 23833 

SUPPLEMENTARY INFORMATION: 

Background 

Congress established ICCVAM to 

promote development, validation, and 

regulatory acceptance of new or revised 

alternative toxicological test methods 

that protect human and animal health 

and the environment while reducing, 

refining, or replacing animal tests and 

ensuring human safety and product 

effectiveness (42 U.S.C. 285l–3). 

Congress has requested that NICEATM 

and ICCVAM, in partnership with 

relevant federal agencies, develop a fiveyear plan that addresses (1) research, 

development, translation, and 

validation of new and revised nonanimal and other alternative assays for 

integration into federal agency testing 

programs and (2) identification of areas 

of high priority for new and revised 

non-animal and alternative assays for 

replacement, reduction, and refinement 

(less pain and distress) of animal tests. 

At this time, the NIEHS and NICEATM 

seek public comments on the draft plan. 

NICEATM and ICCVAM in partnership 

with relevant agency program offices 

will consider these comments in 

development of the final plan. A Town 

Meeting on June 11 will provide the 

public an opportunity to present oral 

comments on the draft plan (see below) 

to NICEATM staff, ICCVAM Agency 

Representatives, and other agency 

program staff. In addition, some 

members of the Scientific Advisory 

Committee on Alternative Toxicological 

Methods (SACATM) will also attend. 

On June 12, 2007, SACATM will meet 

at the Marriott Bethesda North Hotel 

and Conference Center in Bethesda, 

Maryland, where the agenda also 

includes discussion of the draft plan 

(http://ntp.niehs.nih.gov/go/7441) and 

opportunity for oral comments. The 

SACATM meeting will be announced in 

a separate Federal Register notice. 

Registration for the Town Meeting 

The Town Meeting will be held on 

June 11, 2007, at the William H. Natcher 

Conference Center, National Institutes of 

Health, Bethesda, Maryland. Persons 

planning to attend are asked to register 

by June 7, 2007 by completing the 

online registration at the NICEATM– 

ICCVAM Web site (http:// 

iccvam.niehs.nih.gov/meetings/ 

5YPlanTM/townmtg.htm) or by 

contacting NICEATM (see ADDRESSES

above). The agenda is available on the 

NICEATM–ICCVAM Web site (http:// 

iccvam.niehs.nih.gov/meetings/ 

5YPlanTM/townmtg.htm) or can be 

obtained by contacting NICEATM (see 

ADDRESSES above). 

Request for Comments 

The NIEHS and NICEATM invite 

public comments on the draft 

NICEATM–ICCVAM 5-Year Plan. 

Written comments should be submitted 

preferably electronically at the 

NICEATM–ICCVAM 5-Year Plan Web 

site (http://iccvam.niehs.nih.gov/docs/ 

5yearplan.htm). Comments can also be 

submitted by e-mail to 

5yearplan@niehs.nih.gov. Individuals 

submitting comments are asked to 

include appropriate contact information 

(name, affiliation, mailing address, 

phone, fax, e-mail, and sponsoring 

organization, if applicable). All 

comments received by June 7, 2007, will 

be posted on the ICCVAM–NICEATM 

Web site (http://iccvam.niehs.nih.gov/ 

docs/5yearplan.htm) and identified by 

the individual’s name, affiliation (if 

applicable), and/or sponsoring 

organization (if any). 

Persons registering to make oral 

comments at the Town Meeting are 

asked to contact NICEATM (see 

ADDRESSES above) and send a copy of 

their statement by June 7. Written 

statements can supplement and may 

expand the oral presentation. Each 

organization is allowed one speaker. At 

least 7 minutes will be allotted for each 

speaker, and if time permits, may be 

extended up to 10 minutes at the 

discretion of the moderator. Registration 

for oral comments will also be available 

on-site, although time allowed for 

presentation by on-site registrants may 

be less than for pre-registered speakers 

and will be determined by the number 

of persons who register at the meeting. 

If registering on-site and reading from 

written text, please bring 40 copies of 

the statement for distribution and to 

supplement the record. 

Background Information on ICCVAM 

and NICEATM 

ICCVAM is an interagency committee 

composed of representatives from 15 

federal regulatory and research agencies 

that use, generate, or disseminate 

toxicological information. ICCVAM 

conducts technical evaluations of new, 

revised, and alternative methods with 

regulatory applicability and promotes 

scientific validation and regulatory 

acceptance of toxicological test methods 

that more accurately assess safety and 

hazards of chemicals and products and 

that refine, reduce, and replace animal 

use. The ICCVAM Authorization Act of 

2000 (42 U.S.C. 285l–3, available at 

http://iccvam.niehs.nih.gov/docs/ 

about—docs/PL106545.pdf) establishes 

ICCVAM as a permanent interagency 

committee of the NIEHS under 

NICEATM. NICEATM administers 

ICCVAM and provides scientific and 

operational support for ICCVAM-related 

activities. NICEATM and ICCVAM work 

collaboratively to evaluate new and 

improved test methods applicable to the 

needs of federal agencies. SACATM is a 

federally chartered advisory committee 

that provides advice to NICEATM, 

ICCVAM, and NIEHS on ICCVAM and 

NICEATM activities. Additional 

information about ICCVAM and 

NICEATM can be found at the following 

Web site: http://iccvam.niehs.nih.gov. 

Information about SACATM is available 

at http://ntp.niehs.nih.gov/go/167. 

Dated: April 20, 2007. 

Samuel H. Wilson, 

Deputy Director, National Institute of 

Environmental Health Sciences and National 

Toxicology Program. 

[FR Doc. E7–8290 Filed 4–30–07; 8:45 am] 

BILLING CODE 4140–01–P 

DEPARTMENT OF HEALTH AND 

HUMAN SERVICES 

National Toxicology Program (NTP); 

Center for the Evaluation of Risks to 

Human Reproduction (CERHR); 

Second Bisphenol A Expert Panel 

Meeting and Interim Draft Expert Panel 

Report on Bisphenol A: 

Announcement of Postponed Meeting 

and Extension of Public Comment 

Period 

AGENCY: National Institute of 

Environmental Health Sciences 

(NIEHS); National Institutes of Health. 

ACTION: Announcement of postponed 

meeting and extension of public 

comment period. 

SUMMARY: The second meeting of the 

expert panel on bisphenol A originally 

scheduled for May 21–23, 2007 [Federal 

Register, April 2, 2007 (Vol. 72, No. 62, 

page 15695–15696)] is postponed. The 

new date for the meeting will be 

announced in a future Federal Register 

notice. During this time, NTP will 

conduct an independent audit of all 

materials used in the bisphenol-A 

review. Also, the deadline for 

submission of written public comments 

on the interim draft expert panel report 

on bisphenol A is extended until June 

20, 2007. The interim draft report is 

posted on the CERHR Web site (http:// 

cerhr.niehs.nih.gov/chemicals/ 

bisphenol/bisphenol.html) and available 

in printed text from CERHR (see FOR

FURTHER INFORMATION CONTACT below). 

Persons submitting written comments 

are asked to include their name and 

contact information [affiliation (if 

applicable), mailing address, telephone, 

e-mail, and sponsoring organization (if 


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