[Federal Register Volume 72, Number 81 (Friday, April 27, 2007)]
[Notices]
[Pages 21021-21022]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: E7-8073]


-----------------------------------------------------------------------

DEPARTMENT OF HEALTH AND HUMAN SERVICES

Centers for Disease Control and Prevention

[60Day-07-07AW]


Proposed Data Collections Submitted for Public Comment and 
Recommendations

    In compliance with the requirement of Section 3506(c)(2)(A) of the 
Paperwork Reduction Act of 1995 for opportunity for public comment on 
proposed data collection projects, the Centers for Disease Control and 
Prevention (CDC) will publish periodic summaries of proposed projects. 
To request more information on the proposed projects or to obtain a 
copy of the data collection plans and instruments, call 404-639-5960 
and send comments to Joan Karr, CDC Acting Reports Clearance Officer, 
1600 Clifton Road, MS-D74, Atlanta, GA 30333 or send an e-mail to 
<a href="/cdn-cgi/l/email-protection#93fcfef1d3f0f7f0bdf4fce5"><span class="__cf_email__" data-cfemail="f897959ab89b9c9bd69f978e">[email protected]</span></a>.
    Comments are invited on: (a) Whether the proposed collection of 
information is necessary for the proper performance of the functions of 
the agency, including whether the information shall have practical 
utility; (b) the accuracy of the agency's estimate of the burden of the 
proposed collection of information; (c) ways to enhance the quality, 
utility, and clarity of the information to be collected; and (d) ways 
to minimize the burden of the collection of information on respondents, 
including through the use of automated collection techniques or other 
forms of information technology. Written comments should be received 
within 60 days of this notice.

Proposed Project

    Experimental and Theoretical Study of Early Detection and Isolation 
of Influenza--NEW--The National Institute for Occupational Safety and 
Health (NIOSH), Centers for Disease Control and Prevention (CDC).

Background and Brief Description

    The Federal Occupational Safety and Health Act of 1970, section 
501, enables NIOSH to carry out research relevant to the health and 
safety of workers. Some diseases like influenza and Severe Acute 
Respiratory Syndrome (SARS) can be spread when people produce clouds of 
droplets (called aerosols) by coughing or sneezing. Aerosol 
transmission of infectious diseases is of particular interest today 
because of increased concern over a possible global influenza pandemic. 
The possible airborne spread of influenza is especially important to 
health-care workers and emergency responders, who face a much greater 
risk of exposure than does the general public. However, substantial 
gaps exist in our understanding of the generation and spread of 
infectious aerosols containing influenza. This lack of information 
hampers the ability of health scientists to model and predict the 
transmission of influenza by airborne particles and to understand 
whether or not aerosols are likely to be an important route of 
transmission of influenza during a pandemic.
    The purpose of this study is to gain a better understanding of the 
production and dissemination of aerosols containing the influenza 
virus. The results of this research will give scientists and health 
professional's greater insight into the airborne transmission of 
influenza and allow them to better assess the potential effectiveness 
of preventive measures.
    The first part of this study will measure the quantity and size 
distribution of aerosol droplets produced by people with influenza when 
they cough. To accomplish this, volunteers with influenza-like illness 
will be asked to provide an oral swab for influenza testing, and then 
will cough into a spirometer. The aerosol produced by each person will 
be measured using commercially-available instrumentation. The oral 
swabs will be processed after the aerosol experiments are completed.
    The second part of this study will determine the amount and size of 
airborne particles containing influenza virus that are present in a 
hospital emergency department during influenza season. Health care 
workers will be recruited to wear small aerosol collection devices as 
they go about their normal duties. The collected samples will then be 
analyzed for influenza virus. Adult patients in the emergency 
department with influenza-like illness will be asked to provide an oral 
swab to test for the flu virus in order to estimate the number of 
potential sources of viral-laden airborne particles. There will be no 
costs to study participants other than their time.

                                        Estimated Annualized Burden Hours
----------------------------------------------------------------------------------------------------------------
                                                                                     Average
                                                    Number of       Number of      burden per      Total burden
                  Respondents                      respondents    responses per   response (in      (in hours)
                                                                   respondent        hours)
----------------------------------------------------------------------------------------------------------------
Part 1 participants............................              40               2               1             80
Part 2 health care workers.....................              30               1               1             30
Part 2 patients................................              15               1             0.5              8.0
                                                ----------------------------------------------------------------
    Total......................................  ..............  ..............  ..............            118
----------------------------------------------------------------------------------------------------------------



[[Page 21022]]

    Dated: April 23, 2007.
Joan F. Karr,
Acting Reports Clearance Officer, Centers for Disease Control and 
Prevention.
[FR Doc. E7-8073 Filed 4-26-07; 8:45 am]
BILLING CODE 4163-18-P


</pre><script data-cfasync="false" src="/cdn-cgi/scripts/5c5dd728/cloudflare-static/email-decode.min.js"></script></body>
</html>