UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

 

FORM 10-K/A

(Amendment No. 1)

 

(Mark One)

| ☒ | ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 |
|---------|------------------------------------------------------------------------------------------------|

For the fiscal year ended December 31, 2017

OR

| ☐ | TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM                      TO                      |
|---------|---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

Commission File Number 001-37746

 

APTEVO THERAPEUTICS INC.

(Exact name of Registrant as specified in its Charter)

 

 

| Delaware                                                        | 81-1567056                            |
|-----------------------------------------------------------------|---------------------------------------|
| (State or other jurisdiction of

incorporation or organization) | (I.R.S. Employer

Identification No.) |
| 2401 4th Avenue, Suite 1050

Seattle, Washington                | 98121                                 |
| (Address of principal executive offices)                        | (Zip Code)                            |

 

Registrant’s telephone number, including area code: (206) 838-0500

 

Securities registered pursuant to Section 12(b) of the Act: 

 

| Title of Each Class            | Name of Each Exchange on Which Registered |
|--------------------------------|-------------------------------------------|
| Common Stock, $0.001 par value | The Nasdaq Stock Market LLC               |

Securities registered pursuant to Section 12(g) of the Act: 

None

Indicate by check mark if the Registrant is a well-known seasoned issuer, as defined in Rule 405 of the Securities Act. YES ☐ NO ☒

Indicate by check mark if the Registrant is not required to file reports pursuant to Section 13 or 15(d) of the Act. YES ☐ NO ☒

Indicate by check mark whether the Registrant: (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the Registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days. YES ☒ NO ☐

Indicate by check mark whether the Registrant has submitted electronically and posted on its corporate Web site, if any, every Interactive Data File required to be submitted and posted pursuant to Rule 405 of Regulation S-T (§232.405 of this chapter) during the preceding 12 months (or for such shorter period that the Registrant was required to submit and post such files). YES ☒ NO ☐

Indicate by check mark if disclosure of delinquent filers pursuant to Item 405 of Regulation S-K (§229.405) is not contained herein, and will not be contained, to the best of Registrant’s knowledge, in definitive proxy or information statements incorporated by reference in Part III of this Form 10-K or any amendment to this Form 10-K. ☐

Indicate by check mark whether the Registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company or emerging growth company. See the definition of “large accelerated filer”, “accelerated filer”, “smaller reporting company” and “emerging growth company” in Rule 12b-2 of the Exchange Act. (Check one):

 

| Large accelerated filer |   | ☐                                                        |         | Accelerated filer              |   | ☐ |
|-----------------------------------|--------|----------------------------------------------------------------|--------------|-------------------------------------|--------|---------|
|                              |   |                                                           |         |                                |   |    |
| Non-accelerated filer             |   | ☐  (Do not check if a small reporting company) |    | Smaller reporting company |   | ☒ |
|                              |   |                                                           |    | Emerging growth company        |   | ☒ |

 

 

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act.☒

The aggregate market value of common stock held by non-affiliates of the Registrant as of June 30, 2017, the last business day of the registrants most recently completed second fiscal quarter, was $35.8 million, based upon the closing price of the Registrant’s common stock on the Nasdaq Stock Market LLC on such date.  Excludes an aggregate of 4,033,743 shares of the Registrant’s common stock held as of such date by officers, directors, and stockholders that the registrant has concluded are or were affiliates of the Registrant. Exclusion of such shares should not be construed to indicate that the holder of any such shares possesses the power, direct or indirect, to direct or cause the direction of the management or policies of the Registrant or that such person is controlled by or under common control with the Registrant.

 

As of March 9, 2018, the number of shares of Registrant’s common stock outstanding was 21,112,605.

 

DOCUMENTS INCORPORATED BY REFERENCE

Portions of the Registrant’s definitive proxy statement to be filed with the Securities and Exchange Commission pursuant to Regulation 14A, not later than 120 days after the end of the fiscal year covered by this Annual Report on Form 10-K, relating to the Registrant’s 2018 Annual Meeting of Stockholders are incorporated by reference into Part III of this Report.

 

 

 

----

Table of Contents

 

|          |   |                                    |   | Page   |
|---------------|--------|-----------------------------------------|--------|--------|
|          |   |                                    |   |   |
| PART II  |   |                                    |   |   |
| Item 9A. |   | Controls and Procedures                 |   | 4      |
|          |   |                                    |   |   |
| PART IV  |   |                                    |   |   |
| Item 15. |   | Exhibits, Financial Statement Schedules |   | 5      |

 

In this Annual Report on Form 10-K, “we,” “our,” “us,” “Aptevo,” and the “Company” refer to Aptevo Therapeutics Inc. and, where appropriate, its consolidated subsidiaries.

 

 

 

ii

----

EXPLANATORY NOTE

We are filing this Amendment No. 1 to Annual Report on Form 10-K/A (this “Amendment”) to amend our Annual Report on Form 10-K for the fiscal year ended December 31, 2017, as filed with the Securities and Exchange Commission (the “SEC”) on March 13, 2018 (the “10-K”). This Amendment is being filed solely to (1) amend Item 9A and (2) refile the certifications of our principal executive officer and principal financial officer as exhibits to this Amendment as required Pursuant to Rules 13a-14(a) and 15d-14(a) under the Securities Exchange Act of 1934 and pursuant to 18 U.S.C. Section 1350.

No attempt has been made in this Amendment to otherwise modify or update the other disclosures presented in the 10-K. This Amendment does not reflect events occurring after the filing of the original 10-K (i.e., those events occurring after March 13, 2018) or modify or update those disclosures that may be affected by subsequent events. Such subsequent matters are addressed in subsequent reports filed with the SEC. Accordingly, this Amendment should be read in conjunction with the 10-K and our other filings with the SEC.

3

----

PART II

Item 9A. Controls and Procedures.

Evaluation of Disclosure Controls and Procedures

As of December 31, 2017, management, with the participation of our Chief Executive Officer and Chief Financial Officer, performed an evaluation of the effectiveness of the design and operation of our disclosure controls and procedures as defined in Rules 13a- 15(e) and 15d-15(e) of the Exchange Act. Based on this evaluation, our Chief Executive Officer and Chief Financial Officer concluded that, as of December 31, 2017, the design and operation of our disclosure controls and procedures were effective to provide reasonable assurance that information we are required to disclose in reports that we file or submit under the Exchange Act is recorded, processed, summarized, and reported within the time periods specified in the SEC’s rules and forms and to provide reasonable assurance that such information is accumulated and communicated to our management, including our Chief Executive Officer and Chief Financial Officer, as appropriate to allow timely decisions regarding required disclosure. 

 

Management’s Report on Internal Control over Financial Reporting

Management is responsible for establishing and maintaining adequate internal control over financial reporting, as defined in Rule 13a-15(f) of the 1934 Act. Management has assessed the effectiveness of our internal control over financial reporting as of December 31, 2017 based on criteria established in Internal Control—Integrated Framework (2013) issued by the Committee of Sponsoring Organizations of the Treadway Commission. As a result of this assessment, management concluded that, as of December 31, 2017, our internal control over financial reporting was effective in providing reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles.

 

Change in Internal Control over Financial Reporting

There have been no changes in our internal control over financial reporting (as defined in Rules 13a-15(f) and 15d-15(f) under the Exchange Act) during the quarter ended December 31, 2017, that have materially affected, or are reasonably likely to materially affect, our internal control over financial reporting.

 

Limitations on Controls

Because of inherent limitations, disclosure controls and internal control over financial reporting may not prevent or detect misstatements. Also, projections of any evaluation of effectiveness to future periods are subject to the risk that controls may become inadequate because of changes in conditions, or that the degree of compliance with the policies or procedures may deteriorate.

 

4

----

PART IV

Item 15. Exhibits, Financial Statement Schedules.

|   | (a) | The following documents are filed as part of this report (i) the registrant’s Annual Report on Form 10-K filed with the SEC on March 13, 2018 or (ii) this Amendment No. 1 to Annual Report on Form 10-K/A: |
|--------|-----|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|   | 1. | Consolidated Financial Statements |
|--------|----|-----------------------------------|

See Index to Consolidated Financial Statements at Item 8 herein.

|   | 2. | Consolidated Financial Statement Schedules |
|--------|----|--------------------------------------------|

All schedules are omitted because they are not applicable or the required information is shown in the consolidated financial statements or notes thereto.

|   | 3. | Exhibits |
|--------|----|----------|

Exhibit Index

 

| Exhibit

Number |   | Description                                                                                                                                                                                   | Form        | Exhibit     | Filing Date            | File No.          | Filed

Herewith |
|-----------------|--------|-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|-------------|-------------|------------------------|-------------------|-----------------|
|            |   |                                                                                                                                                                                          |        |        |                   |              |            |
| 2.1             |   | Contribution Agreement, dated July 29, 2016, by and among Emergent BioSolutions Inc., Aptevo Therapeutics Inc., Aptevo Research and Development LLC and Aptevo BioTherapeutics LLC            | 8-K         | 2.1         | August 2, 2016         | 001-37746         |            |
|            |   |                                                                                                                                                                                          |        |        |                   |              |            |
| +2.2            |   | Separation and Distribution Agreement, dated July 29, 2016, by and between Emergent BioSolutions Inc. and Aptevo Therapeutics Inc.                                                            | 8-K

  | 2.2

  | August 2, 2016

  | 001-37746

  |            |
|            |   |                                                                                                                                                                                          |        |        |                   |              |            |
| †+2.3     |   | LLC Purchase Agreement, dated as of August 31, 2017, by and among Aptevo BioTherapeutics LLC, Aptevo Therapeutics Inc., Venus Bio Therapeutics Sub LLC, and Saol International Limited.  | 10-Q        | 2.1

  | November 13, 2017      | 001-37746

  |            |
|            |   |                                                                                                                                                                                          |        |        |                   |              |            |
| 3.1             |   | Amended and Restated Certificate of Incorporation of Aptevo Therapeutics Inc.                                                                                                            | 8-K         | 3.1         | August 2, 2016         | 001-37746         |            |
|            |   |                                                                                                                                                                                          |        |        |                   |              |            |
| 3.2             |   | Amended and Restated Bylaws of Aptevo Therapeutics Inc.                                                                                                                                  | 8-K         | 3.2         | August 2, 2016         | 001-37746         |            |
|            |   |                                                                                                                                                                                          |        |        |                   |              |            |
| 4.1             |   | Form of Common Stock Certificate                                                                                                                                                              | 10          | 4.1         | June 29, 2016          | 001-37746         |            |
|            |   |                                                                                                                                                                                          |        |        |                   |              |            |
| 4.2             |   | Registration Rights Agreement, dated as of August 1, 2016, by and among Aptevo Therapeutics Inc. and certain of its stockholders                                                         | 8-K         | 4           | August 2, 2016         | 001-37746         |            |
|            |   |                                                                                                                                                                                          |        |        |                   |              |            |
| 10.1            |   | Promissory Note, dated July 29, 2016, made by Emergent BioSolutions Inc. in favor of Aptevo Therapeutics Inc.                                                                                 | 8-K         | 10.1        | August 2, 2016         | 001-37746         |            |
|            |   |                                                                                                                                                                                          |        |        |                   |              |            |
| 10.2            |   | Transition Services Agreement, dated July 29, 2016, by and between Emergent BioSolutions Inc. and Aptevo Therapeutics Inc.                                                                    | 8-K         | 10.2        | August 2, 2016         | 001-37746         |            |
|            |   |                                                                                                                                                                                          |        |        |                   |              |            |
| 10.3            |   | Tax Matters Agreement, dated July 29, 2016, by and between Emergent BioSolutions Inc. and Aptevo Therapeutics Inc.                                                                            | 8-K         | 10.3        | August 2, 2016         | 001-37746         |            |
|            |   |                                                                                                                                                                                          |        |        |                   |              |            |

5

----

| 10.4    |   | Employee Matters Agreement, dated July 29, 2016, by and between Emergent BioSolutions Inc. and Aptevo Therapeutics Inc.                                                                                                                                                         | 8-K        | 10.4   | August 2, 2016             | 001-37746       |   |
|---------|--------|---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|------------|--------|----------------------------|-----------------|--------|
|    |   |                                                                                                                                                                                                                                                                            |       |   |                       |            |   |
| 10.5    |   | Amended and Restated Manufacturing Services Agreement, dated September 28, 2017, by and between Emergent BioSolutions Inc. and Aptevo Therapeutics Inc.                                                                                                                         | 10-K  | 10.5   | March 12, 2018        | 001-37746  |   |
|    |   |                                                                                                                                                                                                                                                                            |       |   |                       |            |   |
| 10.6    |   | Canadian Distributor Agreement, dated July 29, 2016, by and between Emergent BioSolutions Inc. and Aptevo Therapeutics Inc.                                                                                                                                                     | 8-K        | 10.6   | August 2, 2016             | 001-37746       |   |
|    |   |                                                                                                                                                                                                                                                                            |       |   |                       |            |   |
| 10.7    |   | Amended and Restated Trademark License Agreement, dated September 28, 2017, by and between Emergent BioSolutions Inc. and Aptevo Therapeutics Inc.                                                                                                                              | 10-K  | 10.7   | March 12, 2018   | 001-37746  |   |
|    |   |                                                                                                                                                                                                                                                                            |       |   |                       |            |   |
| 10.8    |   | Product License Agreement, dated July 29, 2016, by and between Emergent BioSolutions Inc. and Aptevo Therapeutics Inc.                                                                                                                                                          | 8-K        | 10.8   | August 2, 2016             | 001-37746       |   |
|    |   |                                                                                                                                                                                                                                                                            |       |   |                       |            |   |
| C 10.9  |   | Aptevo Therapeutics Inc. Amended and Restated 2016 Stock Incentive Plan.                                                                                                                                                                                                        | 10-Q       | 4.1    | August 10, 2017            | 001-37746       |   |
|    |   |                                                                                                                                                                                                                                                                            |       |   |                       |            |   |
| C 10.10 |   | Aptevo Therapeutics Inc. Converted Equity Awards Incentive Plan                                                                                                                                                                                                                 | 8-K        | 10.10  | August 2, 2016             | 001-37746       |   |
|    |   |                                                                                                                                                                                                                                                                            |       |   |                       |            |   |
| C 10.11 |   | Aptevo Therapeutics Inc. Senior Management Severance Plan                                                                                                                                                                                                                       | 8-K        | 10.11  | August 2, 2016             | 001-37746       |   |
|    |   |                                                                                                                                                                                                                                                                            |       |   |                       |            |   |
| C 10.12 |   | Form of Indemnity Agreement for directors and senior officers                                                                                                                                                                                                                   | 10         | 10.9   | April 15, 2016             | 001-37746       |   |
|    |   |                                                                                                                                                                                                                                                                            |       |   |                       |            |   |
| 10.13   |   | Fourth and Battery Office Lease, dated as of April 28, 2003, by and between Emergent Product Development Seattle, LLC (as successor-in-interest to Trubion Pharmaceuticals, Inc. and Genecraft, Inc.) and Selig Real Estate Holdings Eight L.L.C. , or the Seattle Office Lease | 10         | 10.12  | April 15, 2016             | 001-37746       |   |
|    |   |                                                                                                                                                                                                                                                                            |       |   |                       |            |   |
| 10.14   |   | Seattle Office Lease Amendment, dated December 8, 2004                                                                                                                                                                                                                          | 10         | 10.13  | April 15, 2016             | 001-37746       |   |
|    |   |                                                                                                                                                                                                                                                                            |       |   |                       |            |   |
| 10.15   |   | Seattle Office Lease Amendment, dated February 1, 2006                                                                                                                                                                                                                          | 10         | 10.14  | April 15, 2016             | 001-37746       |   |
|    |   |                                                                                                                                                                                                                                                                            |       |   |                       |            |   |
| 10.16   |   | Seattle Office Lease Amendment, dated February 2, 2007                                                                                                                                                                                                                          | 10         | 10.15  | April 15, 2016             | 001-37746       |   |
|    |   |                                                                                                                                                                                                                                                                            |       |   |                       |            |   |
| 10.17   |   | Seattle Office Lease Amendment, dated June 7, 2010                                                                                                                                                                                                                              | 10         | 10.16  | April 15, 2016             | 001-37746       |   |
|    |   |                                                                                                                                                                                                                                                                            |       |   |                       |            |   |
| 10.18   |   | Seattle Office Lease Amendment, dated December 21, 2010                                                                                                                                                                                                                         | 10         | 10.17  | April 15, 2016             | 001-37746       |   |
|    |   |                                                                                                                                                                                                                                                                            |       |   |                       |            |   |
| 10.19   |   | Seattle Office Lease Amendment, dated July 17, 2012                                                                                                                                                                                                                             | 10         | 10.18  | April 15, 2016             | 001-37746       |   |
|    |   |                                                                                                                                                                                                                                                                            |       |   |                       |            |   |
| 10.20   |   | Seventh Amendment to Seattle Office Lease, dated December 5, 2014                                                                                                                                                                                                               | 10         | 10.19  | April 15, 2016             | 001-37746       |   |
|    |   |                                                                                                                                                                                                                                                                            |       |   |                       |            |   |

6

----

| †10.21  |   | License and Co-Development Agreement, dated as of August 19, 2014, by and between Emergent Product Development Seattle, LLC and MorphoSys AG, or the MorphoSys Collaboration Agreement                                                                        | 10          | 10.20        | June 29, 2016              | 001-37746         |   |
|---------------|--------|---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|-------------|--------------|----------------------------|-------------------|--------|
|          |   |                                                                                                                                                                                                                                                          |        |         |                       |              |   |
| †10.22  |   | First Amendment to MorphoSys Collaboration Agreement, dated June 19, 2015                                                                                                                                                                                     | 10          | 10.21        | April 15, 2016             | 001-37746         |   |
|          |   |                                                                                                                                                                                                                                                          |        |         |                       |              |   |
| †10.23  |   | Second Amendment to MorphoSys Collaboration Agreement, dated December 7, 2015                                                                                                                                                                                 | 10          | 10.22        | April 15, 2016             | 001-37746         |   |
|          |   |                                                                                                                                                                                                                                                          |        |         |                       |              |   |
| 10.24         |   | Third Amendment to MorphoSys Collaboration Agreement, dated December 12, 2016                                                                                                                                                                                 | 8-K         | 10.1         | December 15, 2016          | 001-37746         |   |
|          |   |                                                                                                                                                                                                                                                          |        |         |                       |              |   |
| 10.25

  |   | Fourth Amendment MorphoSys Collaboration Agreement, dated June 19, 2017.                                                                                                                                                                                      | 10          | 10.3         | August 10, 2017       | 001-37746         |   |
|          |   |                                                                                                                                                                                                                                                          |        |         |                       |              |   |
| †10.26  |   | Amended and Restated License Agreement, dated as of November 28, 2008, by and between Cangene Corporation (as successor-in-interest to Inspiration Biopharmaceuticals, Inc.) and The University of North Carolina at Chapel Hill, as amended on June 14, 2012 | 10          | 10.23        | April 15, 2016             | 001-37746         |   |
|          |   |                                                                                                                                                                                                                                                          |        |         |                       |              |   |
| †10.27  |   | CMC Commercial Supply (Manufacturing Services) Agreement, dated June 17, 2011, between CMC ICOS Biologics, Inc. and Aptevo BioTherapeutics LLC (as successor-in-interest to Inspiration Biopharmaceuticals, Inc.)                                             | 10          | 10.24        | May 31, 2016               | 001-37746         |   |
|          |   |                                                                                                                                                                                                                                                          |        |         |                       |              |   |
| †10.28  |   | Amended and Restated Commercial Supply Agreement, dated as of June 16, 2017, between CMC ICOS Biologics, Inc. and Aptevo BioTherapeutics LLC.                                                                                                            | 10          | 10.2         | August 10, 2017            | 001-37746         |   |
|          |   |                                                                                                                                                                                                                                                          |        |         |                       |              |   |
| †10.29  |   | Supply Agreement, dated April 29, 2014, between Aptevo BioTherapeutics LLC and Rovi Contract Manufacturing, S.L.                                                                                                                                              | 10          | 10.26        | May 31, 2016               | 001-37746         |   |
|          |   |                                                                                                                                                                                                                                                          |        |         |                       |              |   |
| †10.30  |   | Manufacturing Services Agreement, dated May 27, 2015, Aptevo BioTherapeutics LLC and Patheon UK Limited                                                                                                                                                       | 10          | 10.27        | May 31, 2016               | 001-37746         |   |
|          |   |                                                                                                                                                                                                                                                          |        |         |                       |              |   |
| 10.31         |   | Credit and Security Agreement, dated August 4, 2016 by and among Aptevo Therapeutics Inc., Aptevo Biotherapeutics LLC, Aptevo Research and Development LLC and MidCap Financial Trust, as agent, and the lenders from time to time party thereto.             | 8-K         | 10.1         | August 5, 2016             | 001-37746         |   |
|          |   |                                                                                                                                                                                                                                                          |        |         |                       |              |   |
| 10.32         |   | Fee Letter dated August 4, 2016 by and among Aptevo Therapeutics Inc., Aptevo Biotherapeutics LLC, Aptevo Research and Development LLC and MidCap Financial Trust, as agent.                                                                                  | 8-K         | 10.2         | August 5, 2016             | 001-37746         |   |
|          |   |                                                                                                                                                                                                                                                          |        |         |                       |              |   |
| 10.33

  |   | Third Amendment to License and Co-Development Agreement, dated as of December 12, 2016 by and between Aptevo Research and Development LLC and MorphoSys AG.                                                                                                   | 8-K

  | 10.1

  | December 15,

2016

  | 001-37746

  |   |
|          |   |                                                                                                                                                                                                                                                          |        |         |                       |              |   |
| 10.34         |   | Amendment No.1 to the Credit and Security Agreement, dated May 11, 2017, by and among Aptevo Therapeutics Inc., Aptevo Biotherapeutics LLC and MidCap Financial Trust, as agent and the lenders from time to time thereto                                     | 10-Q        | 10.1         | May 12, 2017               | 001-37746         |   |
|          |   |                                                                                                                                                                                                                                                          |        |         |                       |              |   |

7

----

| 10.35

  |   | Amendment No. 2 to Credit and Security Agreement, dated as of September 28, 2017, by and among Aptevo Therapeutics Inc. and certain of its subsidiaries and Midcap Financial Trust (incorporated by reference to Exhibit 10.1 to the Company’s Current Report on Form 8-K filed on September 29, 2017). | 8-K

  | 1.01

  | September 28, 2017

  | 001-37746

  |   |
|---------------|--------|---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|-------------|--------------|----------------------------|-------------------|--------|
|          |   |                                                                                                                                                                                                                                                                                                          |        |         |                       |              |   |
| 10.36         |   | Equity Distribution Agreement, dated November 9, 2017, between Aptevo Therapeutics, Inc. and Piper Jaffray and Company LLC.                                                                                                                                                                                   | 8-K

  | 1.1

   | November 9, 2017

    | 001-37746         |   |
|          |   |                                                                                                                                                                                                                                                                                                          |        |         |                       |              |   |
| 10.37         |   | Collaboration and Option Agreement, dated as of July 20, 2017, by and between Aptevo Research and Development LLC, and Alligator Bioscience AB.                                                                                                                                                               | 10-Q        | 10.2         | November 13, 2017

   | 001-37746         |   |
|          |   |                                                                                                                                                                                                                                                                                                          |        |         |                       |              |   |
| 10.38         |   | Amendment No. 3 to Credit and Security Agreement, dated as of February 23, 2018, by and among Aptevo Therapeutics Inc. and certain of its subsidiaries and Midcap Financial Trust.                                                                                                                       | 10-K   | 10.38   | March 12, 2018   | 001-37746    |   |
|          |   |                                                                                                                                                                                                                                                                                                          |        |         |                       |              |   |
| 21.1          |   | Subsidiaries of Aptevo Therapeutics Inc.                                                                                                                                                                                                                                                                      | 10          | 21           | June 29, 2016              | 001-37746         |   |
|          |   |                                                                                                                                                                                                                                                                                                          |        |         |                       |              |   |
| 23.1          |   | Consent of Ernst & Young LLP, Independent Registered Public Accounting Firm                                                                                                                                                                                                                               | 10-K   | 23.1         | March 12, 2018   |  001-37746   |   |
|          |   |                                                                                                                                                                                                                                                                                                          |        |         |                       |              |   |
| 31.1          |   | Certification of Principal Executive Officer Pursuant to Rules 13a-14(a) and 15d-14(a) under the Securities Exchange Act of 1934, as Adopted Pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.                                                                                                       |        |         |                       |              | X      |
|          |   |                                                                                                                                                                                                                                                                                                          |        |         |                       |              |   |
| 31.2          |   | Certification of Principal Financial Officer Pursuant to Rules 13a-14(a) and 15d-14(a) under the Securities Exchange Act of 1934, as Adopted Pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.                                                                                                       |        |         |                       |              | X      |
|          |   |                                                                                                                                                                                                                                                                                                          |        |         |                       |              |   |
| 32.1*         |   | Certification of Principal Executive Officer Pursuant to 18 U.S.C. Section 1350, as Adopted Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.                                                                                                                                                        |        |         |                       |              | X      |
|          |   |                                                                                                                                                                                                                                                                                                          |        |         |                       |              |   |
| 32.2*         |   | Certification of Principal Financial Officer Pursuant to 18 U.S.C. Section 1350, as Adopted Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.                                                                                                                                                        |        |         |                       |              | X      |
|          |   |                                                                                                                                                                                                                                                                                                          |        |         |                       |              |   |
| 101.INS       |   | XBRL Instance Document                                                                                                                                                                                                                                                                                        |  10-K  |  101    |  March 12, 2018  |  001-37746   |   |
|          |   |                                                                                                                                                                                                                                                                                                          |        |         |                       |              |   |
| 101.SCH       |   | XBRL Taxonomy Extension Schema Document                                                                                                                                                                                                                                                                       | 10-K   | 101          | March 12, 2018   |  001-37746   |   |
|          |   |                                                                                                                                                                                                                                                                                                          |        |         |                       |              |   |
| 101.CAL       |   | XBRL Taxonomy Extension Calculation Linkbase Document                                                                                                                                                                                                                                                         |  10-K  |  101    | March 12, 2018   |  001-37746   |   |
|          |   |                                                                                                                                                                                                                                                                                                          |        |         |                       |              |   |

8

----

 

| 101.DEF |   | XBRL Taxonomy Extension Definition Linkbase Document   | 10-K  | 101  | March 12, 2018   |  001-37746 |   |
|---------|--------|--------------------------------------------------------|------------|-----------|----------------------------|-----------------|--------|
|    |   |                                                   |       |      |                       |            |   |
| 101.LAB |   | XBRL Taxonomy Extension Label Linkbase Document        | 10-K  | 101  | March 12, 2018   |  001-37746 |   |
|    |   |                                                   |       |      |                       |            |   |
| 101.PRE |   | XBRL Taxonomy Extension Presentation Linkbase Document | 10-K  | 101  | March 12, 2018   |  001-37746 |   |

 

| * | Document has been furnished, is not deemed filed and is not to be incorporated by reference into any of the Company's filings under the Securities Act of 1933, as amended, or the Securities Exchange Act of 1934, as amended, irrespective of any general incorporation language contained in any such filing. |
|---|------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| † | Confidential treatment granted from the Securities and Exchange Commission as to certain portions, which portions have been omitted and filed separately with the Securities and Exchange Commission. |
|---------|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| C | Management contract or compensatory plan. |
|---|-------------------------------------------|

| + | Schedules have been omitted pursuant to Item 601(b)(2) of Regulation S-K. Aptevo will furnish copies of any such schedules to the Securities and Exchange Commission upon request.  |
|---|------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

9

----

SIGNATURES

Pursuant to the requirements of Section 13 or 15(d) of the Securities Exchange Act of 1934, as amended, the Registrant has duly caused this Report to be signed on its behalf by the undersigned, thereunto duly authorized.

 

|                |   | Aptevo Therapeutics, Inc. |
|---------------------|--------|---------------------------|
|                |   |                      |   |   |
| Date: July 27, 2018 |   | By:                       |   | /s/ Marvin L. White |
|                |   |                      |   | Marvin L. White |
|                |   |                      |   | President and Chief Executive Officer |

 

 

10