24324 Federal Register / Vol. 72, No. 84 / Wednesday, May 2, 2007 / Notices 

with prostate cancer each year and the 

disease accounts for nearly one quarter 

of all new cancer diagnoses of all new 

male cancer diagnoses. Worldwide, 

about 395,000 men are diagnosed with 

prostate cancer each year and the 

incidence is on the increase. The total 

direct medical cost of prostate cancer in 

the U.S. is $ 5 billion per year. It is 

estimated that prostate cancer 

therapeutics in the U.S., Europe and 

Japan will cost $ 7.3 billion in 2011. 

The global annual cancer market is 

estimated at $35 billion with breast, 

lung and prostate cancers being the 

most significant contributors. 

Incidences of lung, breast and stomach 

cancers were found to be 351,344, 

220,000, and 25,000 respectively in the 

U.S. The current market size of drugs 

used for the treatment of lung cancer is 

$ 25 billion, while that of breast cancer 

is $3.3 billion. 

Current Competitive Product(s) 

Currently there are no genetic markers 

available to assess the responsiveness of 

an AIPC-patient to therapy before 

starting the treatment. Knowing 

CYP1B1*3 genetic status saves time and 

money of patients and prevents 

ineffective treatments. 

Value Proposition 

The FDA approved dose and schedule 

for docetaxel in combination with 

prednisone in the treatment of 

androgen-independent (hormonerefractory) metastatic prostate cancer is 

75 mg/m2 IV infusion for 1 hour every 

3 weeks with 5 mg prednisone 

continuously and average cost per cycle 

of therapy is $ 4,298. The use of 

docetaxel has been recently shown to 

prolong survival and improve rates of 

response and quality of life, but it is 

unclear which patient would benefit 

from treatment with this drug given that 

high variability in clinical response has 

been observed. A consequence of such 

variability is that a docetaxal treatment 

may be effective in one subject and 

ineffective or poorly tolerated in another 

subject. Thus, administration of such a 

drug to a subject in whom the drug 

would be ineffective would result in 

wasted cost and time during which the 

patient’s condition may significantly 

worsen. Also, administration of a drug 

to subject in whom the drug would not 

be tolerated could result in a direct 

worsening of the patient’s condition and 

could even result in death. This 

technology identifies the polymorphism 

of CYP1B1*3 gene which modulates the 

therapeutic response to docetaxel 

treatment. This genetic marker can be 

measured in DNA obtained from a blood 

sample to predict overall survival in 

patients with prostate cancer prior to 

treatment with docetaxel. Genetic 

markers with predictive power to assess 

inter-subject differences resulting in 

clinical outcome prior to docetaxel 

administration have profound clinical 

importance. 

Intellectual Property Status 

A PCT patent application was filed 09 

September 2006. 

Partnering Opportunity 

Licensing opportunities are available. 

In addition to licensing, the technology 

is available for further development 

through collaborative research 

opportunities with the inventors. 

Licensing Contact: Mojdeh Bahar; 

(301) 435–2950; baharm@mail.nih.gov. 

Collaborative Contact: John D. Hewes, 

Ph.D.; (301) 435–3121; 

hewesj@mail.nih.gov. 

Next Step: Teleconference 

There will be a teleconference where 

the principal investigator will explain 

this technology. Licensing and 

collaborative research opportunities will 

also be discussed. If you are interested 

in participating in this teleconference 

please call or email Mojdeh Bahar; (301) 

435–2950; baharm@mail.nih.gov. OTT 

will then email you the date, time and 

number for the teleconference. 

Dated: April 25, 2007. 

Steven M. Ferguson, 

Director, Division of Technology Development 

and Transfer, Office of Technology Transfer, 

National Institutes of Health. 

[FR Doc. E7–8355 Filed 5–1–07; 8:45 am] 

BILLING CODE 4140–01–P 

DEPARTMENT OF HOUSING AND 

URBAN DEVELOPMENT 

[Docket No. FR–5121–N–14] 

Notice of Proposed Information 

Collection: Comment Request; Section 

202 Supportive Housing for the Elderly 

Application Submission Requirements 

AGENCY: Office of the Assistant 

Secretary for Housing—Federal Housing 

Commissioner, HUD. 

ACTION: Notice. 

SUMMARY: The proposed information 

collection requirement described below 

will be submitted to the Office of 

Management and Budget (OMB) for 

review, as required by the Paperwork 

Reduction Act. The Department is 

soliciting public comments on the 

subject proposal. 

DATES: Comments Due Date: July 2, 

2007. 

ADDRESSES: Interested persons are 

invited to submit comments regarding 

this proposal. Comments should refer to 

the proposal by name and/or OMB 

Control Number and should be sent to: 

Lillian Deitzer, Reports Management 

Officer, Department of Housing and 

Urban Development, 451 7th Street, 

SW., Room 4178, Washington, DC 

20410, or Lillian—L—Deitzer@HUD.gov. 

FOR FURTHER INFORMATION CONTACT: 

Willie Spearmon, Director, Office of 

Housing Assistance and Grant 

Administration, Department of Housing 

and Urban Development, 451 7th Street, 

SW., Washington, DC 20410, telephone 

(202) 708–3000 (this is not a toll free 

number) for copies of the proposed 

forms and other available information. 

SUPPLEMENTARY INFORMATION: The 

Department is submitting the proposed 

information collection to OMB for 

review, as required by the Paperwork 

Reduction Act of 1995 (44 U.S.C. 

Chapter 35, as amended). 

This Notice is soliciting comments 

from members of the public and affected 

agencies concerning the proposed 

collection of information to: (1) Evaluate 

whether the proposed collection is 

necessary for the proper performance of 

the functions of the agency, including 

whether the information will have 

practical utility; (2) Evaluate the 

accuracy of the agency’s estimate of the 

burden of the proposed collection of 

information; (3) Enhance the quality, 

utility, and clarity of the information to 

be collected; and (4) Minimize the 

burden of the collection of information 

on those who are to respond, including 

the use of appropriate automated 

collection techniques or other forms of 

information technology, e.g., permitting 

electronic submission of responses. 

This Notice also lists the following 

information: 

Title of Proposal: Section 202 

Supportive Housing for the Elderly 

Application Submission Requirement. 

OMB Control Number, if applicable: 

2502–0267. 

Description of the need for the 

information and proposed use: The 

collection of this information is 

necessary to the Department to assist 

HUD in determining applicant 

eligibility and ability to develop 

housing for the elderly within statutory 

and program criteria. A thorough 

evaluation of an applicant’s submission 

is necessary to protect the Government’s 

financial interest. 

Agency form numbers, if applicable: 

HUD–92015–CA, HUD–96010, HUD 

92041, SF–424, SF–424–Supplemental, 

SF–LLL, HUD–2880, HUD–2990, HUD– 

2991, HUD–92042, HUD–96010, HUD 

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Federal Register / Vol. 72, No. 84 / Wednesday, May 2, 2007 / Notices 24325 

424B, HUD–27300, HUD–96011, & 

HUD–2994–A. 

Estimation of the total numbers of 

hours needed to prepare the information 

collection including number of 

respondents, frequency of response, and 

hours of response: The estimated 

number of burden hours needed to 

prepare the information collection is 

12,001 the number of respondents is 300 

generating approximately 300 annual 

responses; the frequency of response is 

on occasion; and the estimated time 

needed to prepare the response varies 

from 30 minutes to 21.5 hours. 

Status of the proposed information 

collection: Extension of a currently 

approved collection. 

Authority: The Paperwork Reduction Act 

of 1995, 44 U.S.C., Chapter 35, as amended. 

Dated: April 26, 2007. 

Frank L. Davis, 

General Deputy Assistant Secretary for 

Housing—Deputy Federal Housing 

Commissioner. 

[FR Doc. E7–8327 Filed 5–1–07; 8:45 am] 

BILLING CODE 4210–67–P 

DEPARTMENT OF HOUSING AND 

URBAN DEVELOPMENT 

[Docket No. FR–5121–15] 

Notice of Submission of Proposed 

Information Collection to OMB; 

Application for Insurance of Advance 

of Mortgage Proceeds 

AGENCY: Office of the Assistant 

Secretary for Housing—Federal Housing 

Commissioner, HUD. 

ACTION: Notice. 

SUMMARY: The proposed information 

collection requirement described below 

has been submitted to the Office of 

Management and Budget (OMB) for 

review, as required by the Paperwork 

Reduction Act. The Department is 

soliciting public comments on the 

subject proposal. 

DATES: Comments Due Date: June 1, 

2007. 

ADDRESSES: Interested persons are 

invited to submit comments regarding 

this proposal. Comments should refer to 

the proposal by name and/or OMB 

approval Number (2502–0097) and 

should be sent to: Lillian Deitzer, 

Reports Management Officer, 

Department of Housing and Urban 

Development, 451 7th Street, SW., 

Room 4178, Washington, DC 20401 or 

Lillian—Deitzer@hud.gov. 

FOR FURTHER INFORMATION CONTACT: 

Richard Shearin, Appraiser, Office of 

Multifamily Housing Development, 

Department of Housing and Urban 

Development, 451 Seventh Street, SW., 

Washington, DC 20410; e-mail 

Richard—R.—Shearin@hud.gov; 

telephone (202) 402–2585. This is not a 

toll-free number. 

SUPPLEMENTARY INFORMATION: This 

Notice informs the public that the U.S. 

Department of Housing and Urban 

Development (HUD) has submitted to 

OMB, for emergency processing, a 

survey instrument to obtain information 

from faith based and community 

organizations on their likelihood and 

success at applying for various funding 

programs. This Notice is soliciting 

comments from members of the public 

and affecting agencies concerning the 

proposed collection of information to: 

(1) Evaluate whether the proposed 

collection of information is necessary 

for the proper performance of the 

functions of the agency, including 

whether the information will have 

practical utility; (2) Evaluate the 

accuracy of the agency’s estimate of the 

burden of the proposed collection of 

information; (3) Enhance the quality, 

utility, and clarity of the information to 

be collected; and (4) Minimize the 

burden of the collection of information 

on those who are to respond; including 

through the use of appropriate 

automated collection techniques or 

other forms of information technology, 

e.g., permitting electronic submission of 

responses. 

Title of Proposal: Application for 

Insurance of Advance of Mortgage 

Proceeds. 

OMB Approval Number: 2502–0097. 

Form Numbers: HUD–92403. 

Description of the Need for the 

Information and Its Proposed Use: The 

application for Insurance of Advance of 

Mortgage Proceeds, is submitted by 

mortgagors to request the advance of 

mortgage proceeds to reimburse the 

mortgagor for funds expended or 

obligated for construction related items; 

and by mortgagees to request mortgage 

insurance for funds so advanced. HUD 

transmits the form as its certificate for 

mortgage insurance for funds it 

approves for advance. 

Frequency of Submission: Quarterly. 

I Number of 

respondents 

Annual 

responses x Hours per response = Burden hours 

Reporting Burden ............................................................................. 33,600 16,800 .... 0.2 .... 3,360 

Total Estimated Burden Hours: 3,360. 

Status: Request for extension of an 

existing information collection. 

Authority: The Paperwork Reduction Act 

of 1995, 44 U.S.C. 35, as amended. 

Dated: April 26, 2007. 

Frank L. Davis, 

General Deputy Assistant Secretary for 

Housing, Deputy Federal Housing 

Commissioner. 

[FR Doc. E7–8328 Filed 5–1–07; 8:45 am] 

BILLING CODE 4210–67–P 

DEPARTMENT OF THE INTERIOR 

Fish and Wildlife Service 

Sporting Conservation Council 

AGENCY: Fish and Wildlife Service, 

Interior. 

ACTION: Notice of meeting. 

SUMMARY: This notice announces a 

meeting of the Sporting Conservation 

Council (Council). This meeting is 

designed to review wildlife 

conservation endeavors that benefit 

recreational hunting and wildlife 

resources and that encourage 

partnerships among the public, the 

sporting conservation community, 

wildlife conservation groups, and State 

and Federal governments. This meeting 

is open to the public, and will include 

a session for the public to comment. 

DATES: We will hold the meeting on 

May 23, from 8:30 a.m. to 4:30 p.m. and 

on May 24, from 8:30 a.m. to 4:30 p.m. 

From 1 p.m. to 2 p.m. on May 23, we 

will host a public comment session. 

ADDRESSES: On May 23, the meeting 

will be held in Room 5160 at the 

Department of the Interior, 1849 C 

Street, NW., Washington, DC 20240. On 

May 24, the meeting will be held in 

Room 108–A at the Department of 

Agriculture, 12th and Jefferson Drive, 

SW., Washington, DC 20250. 

FOR FURTHER INFORMATION CONTACT: 

Phyllis T. Seitts, 9828 North 31st 

Avenue, Phoenix, Arizona 85051–2517; 

602–906–5603 (phone); or 

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