Exhibit 10.22


 





 


March 24, 2022


 


Felix Karim, Ph.D.

732 Laurel Drive


Walnut Creek, CA 94596


 


Re: Proposed Compensation Adjustments


 


Dear Felix:


 


Blade Therapeutics, Inc. (the
“Company”) would like to amend the terms of your employment (and your underlying offer letter dated September 30, 2016 (the
“Offer Letter”)) as set forth in this letter (this “Agreement”) to reflect the following adjustments to your compensation,
which will be subject to the consummation of the transactions currently contemplated involving the acquisition of the Company by a special
purpose acquisition company in order to complete a public offering of its common stock, following such transaction the Company or its
successor (a) is required to file periodic reports pursuant to Section 12 of the Securities Exchange Act of 1934, as amended, and (b)
the Company’s common stock (or the successors common stock) is listed on one or more national securities exchanges or is quoted
on NASDAQ or a successor quotation system (the “SPAC Transaction”) and shall be deemed effective upon January 1, 2022 (the
“Effective Date”) following the consummation of the SPAC Transaction (the “Closing”). For purposes hereof, all
references to the Company shall include references to any successor of the Company following the Closing.


 


		1.	Subject to the occurrence of the Closing and your continued employment with the Company from the date
hereof through the Closing, effective as of the Effective Date, your Offer Letter will be deemed amended to provide that your annual base
salary will increase to the monthly rate of $29,166.67 (equivalent to an annualized base salary of $350,000, less applicable taxes and
withholdings to be paid in accordance with the Company’s regular payroll practices.



 


		2.	In addition, subject to the occurrence of the Closing and your continued employment with the Company from
the date hereof through the Closing, effective as of the Effective Date for the full calendar year 2022, your Offer Letter will be deemed
amended to provide that you will be eligible for an annual performance bonus up to 35% of your annual base salary (as adjsuted hereby).
Such annual performance bonus shall otherwise remain subject to the terms and conditions of the Offer Letter (including applicable performance
conditions and timing for payment).



 


		3.	Finally, subject to the occurrence of the Closing and your continued employment with the Company from
the date hereof through the Company’s registration of its shares on a Form S-8 following the Closing, the Company’s board
of directors (or applicable sub-committee) will grant you an option to purchase additional shares of the Company’s common stock
thereby adjusting your overall equity ownership to the seventy fifth (75%), percentile or .67%, with an exercise price per share equal
to the fair market value of the common stock of the Company (or its successor) on the date of grant (the “Option”). The number
of shares subject to the Option shall be adjusted in accordance with the transaction documents evidencing the SPAC Transaction, as if
the Option was outstanding as of the date hereof. The Option shall vest as to 1/48th of the shares subject to the Option on
each monthly anniversary of the effectvie date as determined by the board, subject to your continuing service with the Company hrough
each relevant vesting date. The Option shall be subject to the terms and conditions of the Company’s equity plan to be approved
in connection with the SPAC Transaction and an individual Option agreement between you and the Company.



 


This Agreement, collectively
with your Offer Letter (as amended by this Agreement) and the other documents referenced herein, constitutes the entire agreement between
you and the Company with respect to the subject matter hereof and supersedes and merges all prior agreements or understandings, whether
written or oral. You understand that the amendment to your Offer Letter to reflect the terms of this Agreement will become effective only
upon the Closing (subject to your continued employment through such date), and in the event the Closing does not occur or your employment
with the Company is termianted for any reason prior to the Closing, this Agreement shall be no further force or effect. You acknowledge
that, except as provided in this Agreement, your Offer Letter shall remain in full force and effect.


 





 






     


     


    

 





 


If the foregoing accurately reflects our agreement, please sign this
Agreement and return a copy to me by April 8, 2022.


 


	 	 	 	 	Very truly yours,
	 	 	 	 	Blade Therapeutics, Inc.
	 	 	 	 	 
	 	 	 	 	 
	 	 	 	 	By:	Wendye Robbins, M.D.
	 	 	 	 	Title:	President & CEO
	 	 	 	 	 	 
	Accepted and Agreed to by:	 	 	 
	 	 	 	 	 	 
	 	 	 	 	 	 
	Felix Karim, Ph.D.	 	Date